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Conserved domains on  [gi|489933515|ref|WP_003836829|]
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MULTISPECIES: iron ABC transporter permease [Citrobacter]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 36-351 2.36e-101

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 301.22  E-value: 2.36e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  36 GISIGETFIPWRHVLSTLanhlfdTHYPVDALDAGIVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLLGISA 115
Cdd:COG0609    1 SLSLGAVPISLSDVLRAL------LGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 116 GASTGAVLIALTGLGAGIISMSLGAFIGALTAFLFVALLAmaagGKQGGGITTQIILAGIASSQLFNAITSLIITRsANA 195
Cdd:COG0609   75 GAALGAVLAIVLGGGLSALGLPLAAFLGALLAALLVYLLA----RRGGGLSPLRLVLAGVAVSALFSALTSLLLLL-ADP 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 196 EQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIMVS 275
Cdd:COG0609  150 EQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVA 229

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489933515 276 IVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLLPGQVLPIGVITALVGAPAFSIILIRG 351
Cdd:COG0609  230 VAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 36-351 2.36e-101

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 301.22  E-value: 2.36e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  36 GISIGETFIPWRHVLSTLanhlfdTHYPVDALDAGIVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLLGISA 115
Cdd:COG0609    1 SLSLGAVPISLSDVLRAL------LGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 116 GASTGAVLIALTGLGAGIISMSLGAFIGALTAFLFVALLAmaagGKQGGGITTQIILAGIASSQLFNAITSLIITRsANA 195
Cdd:COG0609   75 GAALGAVLAIVLGGGLSALGLPLAAFLGALLAALLVYLLA----RRGGGLSPLRLVLAGVAVSALFSALTSLLLLL-ADP 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 196 EQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIMVS 275
Cdd:COG0609  150 EQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVA 229

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489933515 276 IVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLLPGQVLPIGVITALVGAPAFSIILIRG 351
Cdd:COG0609  230 VAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 32-350 5.34e-77

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 239.35  E-value: 5.34e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515   32 VLLAGISIGETFIPWRHVLSTLANhlfdthyPVDALDAGIVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLL 111
Cdd:pfam01032   5 LILLSLFIGAVKISPSDVFSALLG-------GDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSIL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  112 GISAGASTGAVLIALTGLGAGIISMSLGAFIGALTAFLFVALLAmaagGKQGGGITTQIILAGIASSQLFNAITSLIITR 191
Cdd:pfam01032  78 GISSGAALGAVLAILLGGSLSLFALPLAAFIGALLAALLVYFLS----RGRGGASPLRLILAGIAVSALLSALTSLLLLL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  192 sANAEQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTA 271
Cdd:pfam01032 154 -LNPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTA 232

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489933515  272 IMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLLPGQVLPIGVITALVGAPAFSIILIR 350
Cdd:pfam01032 233 ASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 35-351 1.11e-69

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 220.88  E-value: 1.11e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515   35 AGISIGETfipWRHVLSTLANHLFDTHYPVDALDAGIVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLLGIS 114
Cdd:TIGR03869  15 ADISVGEV---WRSVAAHLGRGEGFPGVALSRLQDAIVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  115 AGASTGAVLIALTGLGagiISMSLGAFIGALTAflFVALLAMAaggKQGGGIT-TQIILAGIASSQLFNAITSLIITRSA 193
Cdd:TIGR03869  92 SGASLGAVAVLVLGVA---VLLPVAAFAGALLA--LAATLGLA---RTLGTLTpTRTILAGLAVSQLCAAVTSFVIFWSA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  194 NAEQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIM 273
Cdd:TIGR03869 164 TGDSYREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLASGRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGAL 243

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489933515  274 VSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLLPGQVLPIGVITALVGAPAFSIILIRG 351
Cdd:TIGR03869 244 VSVSGAIGFVGLILPHAVRLLTGPRHRLLLPVSALAGAVFLVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRS 321
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
4-352 3.71e-60

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 204.69  E-value: 3.71e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515   4 SRRMRRAVGQLAVRVGGHAVWVSALMCCVLLAGISIGETFIPWRHVlstlanhlfdthypvDALDAGIVWNYRLTRALVS 83
Cdd:PRK10577 340 AMSAGDRVAARRRRVLAWLLALGLLLLLALVVALSFGRDAHGWNWL---------------SGQLLDALLPLRLPRLLAA 404

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  84 ASCGACLAVSGVVLQSLLRNALAEPYLLGISAGASTGAVLIALTGLGAGIISMSLGAFIGALTAFLFVALLAmaaggKQG 163
Cdd:PRK10577 405 LLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALAALALILLLA-----RRG 479

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 164 GGITTQIILAGIASSQLFNAITSLIITRSAnaEQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSF 243
Cdd:PRK10577 480 GFAPERLLLTGIALSALFTALIQLLLASGD--PRAAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPL 557

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 244 GAESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRT 323
Cdd:PRK10577 558 GDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRT 637

                        330       340
                 ....*....|....*....|....*....
gi 489933515 324 LLPGQVLPIGVITALVGAPAFSIILIRGN 352
Cdd:PRK10577 638 LLFPYQIPAGLLAALIGAPYFLWLLRRSR 666
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 86-348 1.50e-46

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 158.87  E-value: 1.50e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  86 CGACLAVSGVVLQSLLRNALAEPYLLGISAGASTGAVLIALTGLGAGIISMSLGAFIGALTAFLFVALLAmaaggKQGGG 165
Cdd:cd06550    7 VGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLA-----SRGGL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 166 ITTQIILAGIASSQLFNAITSLIITRSANAEQArgIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGA 245
Cdd:cd06550   82 SPSKLILIGIVLSAFFSAGVILISLLSDDSLQD--LNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 246 ESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLL 325
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239

                        250       260
                 ....*....|....*....|...
gi 489933515 326 PGQvLPIGVITALVGAPAFSIIL 348
Cdd:cd06550  240 PSE-LPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 36-351 2.36e-101

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 301.22  E-value: 2.36e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  36 GISIGETFIPWRHVLSTLanhlfdTHYPVDALDAGIVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLLGISA 115
Cdd:COG0609    1 SLSLGAVPISLSDVLRAL------LGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 116 GASTGAVLIALTGLGAGIISMSLGAFIGALTAFLFVALLAmaagGKQGGGITTQIILAGIASSQLFNAITSLIITRsANA 195
Cdd:COG0609   75 GAALGAVLAIVLGGGLSALGLPLAAFLGALLAALLVYLLA----RRGGGLSPLRLVLAGVAVSALFSALTSLLLLL-ADP 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 196 EQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIMVS 275
Cdd:COG0609  150 EQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVA 229

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489933515 276 IVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLLPGQVLPIGVITALVGAPAFSIILIRG 351
Cdd:COG0609  230 VAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 32-350 5.34e-77

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 239.35  E-value: 5.34e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515   32 VLLAGISIGETFIPWRHVLSTLANhlfdthyPVDALDAGIVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLL 111
Cdd:pfam01032   5 LILLSLFIGAVKISPSDVFSALLG-------GDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSIL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  112 GISAGASTGAVLIALTGLGAGIISMSLGAFIGALTAFLFVALLAmaagGKQGGGITTQIILAGIASSQLFNAITSLIITR 191
Cdd:pfam01032  78 GISSGAALGAVLAILLGGSLSLFALPLAAFIGALLAALLVYFLS----RGRGGASPLRLILAGIAVSALLSALTSLLLLL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  192 sANAEQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTA 271
Cdd:pfam01032 154 -LNPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTA 232

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489933515  272 IMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLLPGQVLPIGVITALVGAPAFSIILIR 350
Cdd:pfam01032 233 ASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 35-351 1.11e-69

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 220.88  E-value: 1.11e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515   35 AGISIGETfipWRHVLSTLANHLFDTHYPVDALDAGIVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLLGIS 114
Cdd:TIGR03869  15 ADISVGEV---WRSVAAHLGRGEGFPGVALSRLQDAIVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  115 AGASTGAVLIALTGLGagiISMSLGAFIGALTAflFVALLAMAaggKQGGGIT-TQIILAGIASSQLFNAITSLIITRSA 193
Cdd:TIGR03869  92 SGASLGAVAVLVLGVA---VLLPVAAFAGALLA--LAATLGLA---RTLGTLTpTRTILAGLAVSQLCAAVTSFVIFWSA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  194 NAEQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIM 273
Cdd:TIGR03869 164 TGDSYREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLASGRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGAL 243

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489933515  274 VSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLLPGQVLPIGVITALVGAPAFSIILIRG 351
Cdd:TIGR03869 244 VSVSGAIGFVGLILPHAVRLLTGPRHRLLLPVSALAGAVFLVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRS 321
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 24-350 2.13e-62

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 202.01  E-value: 2.13e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  24 WVSALMCCVLLA---GISIGETFIPWRHVLSTLANHlfdthypvdaldagIVWNYRLTRALVSASCGACLAVSGVVLQSL 100
Cdd:COG4139   14 WLLLLLLLLLLLfvlSLCAGEVWIPPTQWLSEAWQL--------------FVWQLRLPRTLAAVLVGASLAVSGAVMQAL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 101 LRNALAEPYLLGISAGASTGAVLIALTGLGA-GIISMSLGAFIGALTAFLFvaLLAMAAGGKQgggiTTQIILAGIASSQ 179
Cdd:COG4139   80 FENPLAEPGLLGISNGAGVGLVLVVLLGGGLlPPWLLSLAAIAGALLVTLL--LLAFARRRLS----NARLLLIGVALGI 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 180 LFNAITSLIITRSaNAEQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCfCYARHLDAFSFGAESAASLGIPVKRTR 259
Cdd:COG4139  154 ICSAIMTWAVYFS-SSLDLRQLMYWMMGSFGGVDWRQLWLLLALLPVLLWLC-LQGKPLNLLLLGENQARQLGLSVHRWR 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 260 AVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLLPGQVLPIGVITALV 339
Cdd:COG4139  232 NLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALLLLADIIARLALSSAELPIGVVTATL 311

                        330
                 ....*....|.
gi 489933515 340 GAPAFSIILIR 350
Cdd:COG4139  312 GAPVFIWLLLR 322
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
4-352 3.71e-60

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 204.69  E-value: 3.71e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515   4 SRRMRRAVGQLAVRVGGHAVWVSALMCCVLLAGISIGETFIPWRHVlstlanhlfdthypvDALDAGIVWNYRLTRALVS 83
Cdd:PRK10577 340 AMSAGDRVAARRRRVLAWLLALGLLLLLALVVALSFGRDAHGWNWL---------------SGQLLDALLPLRLPRLLAA 404

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  84 ASCGACLAVSGVVLQSLLRNALAEPYLLGISAGASTGAVLIALTGLGAGIISMSLGAFIGALTAFLFVALLAmaaggKQG 163
Cdd:PRK10577 405 LLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALAALALILLLA-----RRG 479

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 164 GGITTQIILAGIASSQLFNAITSLIITRSAnaEQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSF 243
Cdd:PRK10577 480 GFAPERLLLTGIALSALFTALIQLLLASGD--PRAAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPL 557

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 244 GAESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRT 323
Cdd:PRK10577 558 GDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRT 637

                        330       340
                 ....*....|....*....|....*....
gi 489933515 324 LLPGQVLPIGVITALVGAPAFSIILIRGN 352
Cdd:PRK10577 638 LLFPYQIPAGLLAALIGAPYFLWLLRRSR 666
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 24-350 1.09e-55

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 184.77  E-value: 1.09e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  24 WVSALMCCVLLA---GISIGETFIPWRHVLSTLAnHLFdthypvdaldagiVWNYRLTRALVSASCGACLAVSGVVLQSL 100
Cdd:PRK03784  17 WLLGLSVLLLLAlllSLCAGEQWISPGDWLSPRG-ELF-------------VWQLRLPRTLAVLLVGAALAVSGAVMQAL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 101 LRNALAEPYLLGISAGASTGAVLIALTGLGA-GIISMSLGAFIGALTAFLFvaLLAMAAGGKQGggiTTQIILAGIASSQ 179
Cdd:PRK03784  83 FENPLAEPGLLGVSNGAGVALVAAVLLGQGLlPPWALSLCAIAGALLITLI--LLRFARRHRLS---TSRLLLAGVALGI 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 180 LFNAITSLIITRSANAEqARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCfCYARHLDAFSFGAESAASLGIPVKRTR 259
Cdd:PRK03784 158 ICSALMTWAVYFSTSLD-LRQLMYWMMGGFGGVDWRQSWLMLALLPVLIWLC-CQGRPLNMLALGEISARQLGLPLWFWR 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 260 AVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLLPGQVLPIGVITALV 339
Cdd:PRK03784 236 NLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLADIVARLALASAELPIGVVTATL 315

                        330
                 ....*....|.
gi 489933515 340 GAPAFSIILIR 350
Cdd:PRK03784 316 GAPVFIWLLLR 326
btuC PRK09535
cobalamin ABC transporter permease BtuC;
62-350 9.39e-54

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 181.10  E-value: 9.39e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  62 YPVDALDAGIVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLLGISAGASTGAVlIALTGLGAGIISMSLGAF 141
Cdd:PRK09535  81 FAVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAV-AAIVLPLAVPFGLQAAAF 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 142 IGALTAFLFVALLAMaaggKQGGGITTQIILAGIASSQLFNAITSLIITRSAnaEQARGIMFWLLGNLSGVRWPDVVLAI 221
Cdd:PRK09535 160 AGALVAAFGVYAIAT----ENGRTPVATLLLAGVAVQTFLGAVISYLLLHSG--ESLRRAVYWLMGHLHGSTWSDVEVAL 233

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 222 PTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHR 301
Cdd:PRK09535 234 PVVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRI 313

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 489933515 302 LLPVSALTGAIFLIVADVISRTllPGQVLPIGVITALVGAPAFSIILIR 350
Cdd:PRK09535 314 LLPTSALAGASFLVATDTVARS--GPAEVPVGIVTAALGAPFFLYLLRT 360
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
64-343 2.10e-51

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 181.19  E-value: 2.10e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  64 VDALDAGIVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLLGISAGASTGAVLIALTGLGAGIISMSLGAFIG 143
Cdd:PRK10577  50 ADDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQQVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASQLAAFAG 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 144 ALTAFLFVALLAmaaGGKQGGGITtqIILAGIASSQLFNAITSLIItrSANAEQARGIMFWLLGNLSGVRWPDVVLAIPT 223
Cdd:PRK10577 130 GLLAAALVFALA---GGKRLSPLR--LVLAGMVVSLYLGALTTLLL--LFNEQYLQGLFLWGAGSLAQNDWSGVQRLLPR 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 224 ALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLL 303
Cdd:PRK10577 203 LLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARL 282

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 489933515 304 PVSALTGAIFLIVADVISRTLLP--GQVLPIGVITALVGAPA 343
Cdd:PRK10577 283 PLSPLIGALLLLLTDQLVRLLAGvgGELLPTGAVTALIGAPL 324
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
27-350 2.20e-51

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 173.31  E-value: 2.20e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  27 ALMCCVLLAgISIGETFIPWRHVLStlANHLFDTHYPVdaldagiVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALA 106
Cdd:PRK09777  12 ALAGCALLS-LRMGVIPLPWRALLT--DWQAGDEHYYV-------LMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 107 EPYLLGISAGASTGAVLIALTGLGAGIISMSLGAFIGALTAFLfvaLLAMAAGGKQgggiTTQIILAGIASSQLFNAITS 186
Cdd:PRK09777  82 SPDILGVNHAASLASVGALLLFPSLPVMWLPLLAFIGGMAGLI---LLKMLAGTHQ----PMKLALTGVALSALWASLTD 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 187 -LIITRSANAEQArgiMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAA 265
Cdd:PRK09777 155 yLMLSRPQDINNA---LLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 266 VTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLLPGQVLPIGVITALVGAPAFS 345
Cdd:PRK09777 232 AVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFF 311


                 ....*
gi 489933515 346 IILIR 350
Cdd:PRK09777 312 WLLVR 316
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
64-351 4.80e-47

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 162.17  E-value: 4.80e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  64 VDALDAGIVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLLGISAGASTGAVLIalTGLGAGIISMSLGAFIG 143
Cdd:PRK11228  39 TPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALT--SALSPTPFAGYSLAFIA 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 144 ALTAFLFVALLAMAAGGKQGGGITTQIILAGIASSQLFNAITSLIITRSAnaEQARGIMFWLLGNLSGVRWPDVVLAIPT 223
Cdd:PRK11228 117 ACGGGLSWLLVMTAGGGWRHTHDRNRLILAGIALSALCMALTRITLLLAE--DHAYGIFYWLAGGVSHARWQEVWQLLPF 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 224 ALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLL 303
Cdd:PRK11228 195 VVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVL 274

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 489933515 304 PVSALTGAIFLIVADVISRTLLPGQVLPIGVITALVGAPAFsIILIRG 351
Cdd:PRK11228 275 PMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCF-VWLARR 321
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 86-348 1.50e-46

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 158.87  E-value: 1.50e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  86 CGACLAVSGVVLQSLLRNALAEPYLLGISAGASTGAVLIALTGLGAGIISMSLGAFIGALTAFLFVALLAmaaggKQGGG 165
Cdd:cd06550    7 VGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLA-----SRGGL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 166 ITTQIILAGIASSQLFNAITSLIITRSANAEQArgIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGA 245
Cdd:cd06550   82 SPSKLILIGIVLSAFFSAGVILISLLSDDSLQD--LNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 246 ESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVISRTLL 325
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239

                        250       260
                 ....*....|....*....|...
gi 489933515 326 PGQvLPIGVITALVGAPAFSIIL 348
Cdd:cd06550  240 PSE-LPVGPVTALLGAPYFLYLL 261
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
1-354 5.23e-36

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 133.29  E-value: 5.23e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515   1 MSDSRRMRRAVGQLAVRVgghavwvsaLMCCVLLAGISIGETFIPwrhvLSTLANHLFDTHYPVDALdagIVWNYRLTRA 80
Cdd:PRK10441   1 MSGSVAVTRAIAVPGLLL---------LLIIATALSLLIGAKSLP----ASVVLEALSGTCQSADCT---IVLDARLPRT 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  81 LVSASCGACLAVSGVVLQSLLRNALAEPYLLGISAGASTGAVL-IALTGLGAGIISMSLgAFIGALTAFLFVALLamaag 159
Cdd:PRK10441  65 LAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLgAALFGYSSAQEQLAM-AFAGALVASLIVAFT----- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 160 GKQGGGITT--QIILAGIASSQLFNAITSLIITrsANAEQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARH 237
Cdd:PRK10441 139 GSQGGGQLSpvRLTLAGVALAAVLEGLTSGIAL--LNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRA 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 238 LDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLPVSALTGAIFLIVA 317
Cdd:PRK10441 217 LNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFA 296

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 489933515 318 DVISRTLLPGQvLPIGVITALVGAPAFsIILIRGNQN 354
Cdd:PRK10441 297 DIIGRLLVPGE-LRVSVVSAFIGAPVL-IFLVRRKTR 331
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
71-355 3.26e-30

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 117.50  E-value: 3.26e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  71 IVWNYRLTRALVSASCGACLAVSGVVLQSLLRNALAEPYLLGISAGASTGaVLIALTGLGAGIISMSLGAFIGALTAFLF 150
Cdd:PRK10440  54 VVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSG-VLVAMVLFGQDLTAIALAAMAGGIVTSLL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 151 VALLAMAAGGKqgggiTTQIILAGIASSQLFNAITSLIITrSANAEQARGIMFWLLGNLSGVRWPDVVLAIPTALVGIAL 230
Cdd:PRK10440 133 VWLLAWRNGID-----TFRLIIIGIGVRAMLVAFNTWLLL-KASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIA 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 231 CFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAIGFVGLVIPHAARLLVGNQHHRLLpVSALTG 310
Cdd:PRK10440 207 AALLVRRMRLLEMGDDTACALGVSVERSRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLT-QAALCG 285

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 489933515 311 AIFLIVADVISRTLLPGQVLPIGVITALVGAPAFSIILIRGNQNK 355
Cdd:PRK10440 286 ALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK 330
ZnuB COG1108
ABC-type Mn2+/Zn2+ transport system, permease component [Inorganic ion transport and ...
 124-321 4.07e-09

ABC-type Mn2+/Zn2+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440725  Cd Length: 260  Bit Score: 56.59  E-value: 4.07e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 124 IALTGLGAGI---ISMSLGAFIGALTAFLFVALLamaaggKQGGGITTQIILAGIASSQLfnAITSLIITRSANAeqARG 200
Cdd:COG1108   40 AALPGVALAFllgLSPLLGALVAGLLAALLIGLL------RRRSRLKEDTAIGIVFSGGF--ALGVLLISLVPGS--AVD 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515 201 IMFWLLGNLSGVRWPDVVLAIPTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAI 280
Cdd:COG1108  110 LMSYLFGSILAVSRSDLLLLAVLAAVVLLLLLLFYRELLLVSFDPELARASGLPVRLLHLLLLVLLALTVVAALQAVGAL 189

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 489933515 281 GFVGL-VIPHAARLLVGNQHHRLLPVSALTGAIFLIVADVIS 321
Cdd:COG1108  190 LVSALlIIPAATARLLTRSLRRMLLLAVLIGVLSSVLGLYLS 231
ABC-3 pfam00950
ABC 3 transport family;
134-351 1.09e-03

ABC 3 transport family;


Pssm-ID: 334323  Cd Length: 258  Bit Score: 40.29  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  134 ISMSLGAFIGALTAFLFVALLAMAAGGKQGGGIttqiilaGIASSQLFnAITSLIITRSANAEQarGIMFWLLGNLSGVR 213
Cdd:pfam00950  54 INPAIGAFVFGLIAAVAMGYLKRKTRLKEDTAI-------GIVFSTFL-ALGLVLISLIPGSAV--DLDSYLFGNILTIS 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489933515  214 WPDVVLAIPTALVGIALCFCYARHLDAFSFGAESAASLGIPVKRTRAVLIAAVTGMTAIMVSIVGAIGFVG-LVIPHAAR 292
Cdd:pfam00950 124 QQDLIQIAIITAVILILLLLFWKELLLITFDPDHAKVIGLPVQFLYLLLLALIALTIVVALQAVGAILVIAlLIIPAATA 203

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 489933515  293 LLVGNQHHRLLPVSALTGAIFLIVADVISRTLlpgqVLPIGVITALVGAPAFSIILIRG 351
Cdd:pfam00950 204 RRLTRSFDSMLIIAILIGMVSCVAGLYLSYYF----DTSTGPVIVLIATLLFLISLAFA 258
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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