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Conserved domains on  [gi|489910839|ref|WP_003814252|]
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MULTISPECIES: cell division topological specificity factor MinE [Bordetella]

Protein Classification

cell division topological specificity factor MinE( domain architecture ID 10014521)

cell division topological specificity factor MinE prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites

CATH:  3.30.1070.10
Gene Symbol:  minE
Gene Ontology:  GO:0051301
PubMed:  9393861|11062554
SCOP:  4001444

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK13989 PRK13989
cell division topological specificity factor MinE; Provisional
 1-82 1.27e-46

cell division topological specificity factor MinE; Provisional


:

Pssm-ID: 184442  Cd Length: 84  Bit Score: 143.30  E-value: 1.27e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489910839  1 MSFLSFLLGQKKSSASVAKERLQIILAHER-GRGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVLEVKIE 79
Cdd:PRK13989  1 MSILSFLLGEKKKTASVAKERLQIIIAHERvGGRQPPDYLPALQKELVAVISKYVKISPDDIRVSLERQDNLEVLEVKIE 80


                ...
gi 489910839 80 MPQ 82
Cdd:PRK13989 81 LPQ 83
 
Name Accession Description Interval E-value
PRK13989 PRK13989
cell division topological specificity factor MinE; Provisional
 1-82 1.27e-46

cell division topological specificity factor MinE; Provisional


Pssm-ID: 184442  Cd Length: 84  Bit Score: 143.30  E-value: 1.27e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489910839  1 MSFLSFLLGQKKSSASVAKERLQIILAHER-GRGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVLEVKIE 79
Cdd:PRK13989  1 MSILSFLLGEKKKTASVAKERLQIIIAHERvGGRQPPDYLPALQKELVAVISKYVKISPDDIRVSLERQDNLEVLEVKIE 80


                ...
gi 489910839 80 MPQ 82
Cdd:PRK13989 81 LPQ 83
MinE COG0851
Septum formation topological specificity factor MinE [Cell cycle control, cell division, ...
 1-82 3.85e-41

Septum formation topological specificity factor MinE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440612  Cd Length: 84  Bit Score: 129.45  E-value: 3.85e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489910839  1 MSFLSFLLGQKKSSASVAKERLQIILAHERgRGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVLEVKIEM 80
Cdd:COG0851   1 MSLLDFFRGRKKSSADVAKERLQLVLAHDR-AGLSPDYLEQLKKEILEVISKYVEIDEDAVEVSLEREDDLSALEANIPL 79


                ..
gi 489910839 81 PQ 82
Cdd:COG0851  80 PR 81
MinE pfam03776
Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to ...
 14-80 1.70e-27

Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to code for three gene products (MinC, MinD, and MinE) whose coordinate action is required for proper placement of the division septum. The minE gene codes for a topological specificity factor that, in wild-type cells, prevents the division inhibitor from acting at internal division sites while permitting it to block septation at polar sites.


Pssm-ID: 461046  Cd Length: 67  Bit Score: 94.37  E-value: 1.70e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489910839  14 SASVAKERLQIILAHERGRGdSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQD-TLEVLEVKIEM 80
Cdd:pfam03776  1 SANVAKERLQLILAHDRADL-SPDYLEQLKNEILEVISKYVEIDEEKVEVQLEQDDgDVSVLEANIPL 67
minE TIGR01215
cell division topological specificity factor MinE; This protein is involved in the process of ...
 1-81 4.93e-27

cell division topological specificity factor MinE; This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division]


Pssm-ID: 188120  Cd Length: 81  Bit Score: 93.58  E-value: 4.93e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489910839   1 MSFLSFLLGQKKSSASVAKERLQIILAHERGrGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVLEVKIEM 80
Cdd:TIGR01215  1 MSLLEFFKSRKKNSAEVAKDRLKLILAHERA-QLAPEYLEELRKEILEVISKYVEIDPEMVEVSLESQGDMSVLELNITL 79


                 .
gi 489910839  81 P 81
Cdd:TIGR01215 80 P 80
 
Name Accession Description Interval E-value
PRK13989 PRK13989
cell division topological specificity factor MinE; Provisional
 1-82 1.27e-46

cell division topological specificity factor MinE; Provisional


Pssm-ID: 184442  Cd Length: 84  Bit Score: 143.30  E-value: 1.27e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489910839  1 MSFLSFLLGQKKSSASVAKERLQIILAHER-GRGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVLEVKIE 79
Cdd:PRK13989  1 MSILSFLLGEKKKTASVAKERLQIIIAHERvGGRQPPDYLPALQKELVAVISKYVKISPDDIRVSLERQDNLEVLEVKIE 80


                ...
gi 489910839 80 MPQ 82
Cdd:PRK13989 81 LPQ 83
MinE COG0851
Septum formation topological specificity factor MinE [Cell cycle control, cell division, ...
 1-82 3.85e-41

Septum formation topological specificity factor MinE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440612  Cd Length: 84  Bit Score: 129.45  E-value: 3.85e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489910839  1 MSFLSFLLGQKKSSASVAKERLQIILAHERgRGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVLEVKIEM 80
Cdd:COG0851   1 MSLLDFFRGRKKSSADVAKERLQLVLAHDR-AGLSPDYLEQLKKEILEVISKYVEIDEDAVEVSLEREDDLSALEANIPL 79


                ..
gi 489910839 81 PQ 82
Cdd:COG0851  80 PR 81
minE PRK00296
cell division topological specificity factor MinE; Reviewed
 1-83 2.28e-38

cell division topological specificity factor MinE; Reviewed


Pssm-ID: 234718  Cd Length: 86  Bit Score: 122.27  E-value: 2.28e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489910839  1 MSFLSFLLGQKKSSASVAKERLQIILAHERGRGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVLEVKIEM 80
Cdd:PRK00296  1 MSLLDFFRSRKKSTANVAKERLQIIVAHERSSRGEPDYLPQLRKEILEVIAKYVQIDPDKVSVQLDKDGDISTLELNVTL 80


                ...
gi 489910839 81 PQN 83
Cdd:PRK00296 81 PEA 83
MinE pfam03776
Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to ...
 14-80 1.70e-27

Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to code for three gene products (MinC, MinD, and MinE) whose coordinate action is required for proper placement of the division septum. The minE gene codes for a topological specificity factor that, in wild-type cells, prevents the division inhibitor from acting at internal division sites while permitting it to block septation at polar sites.


Pssm-ID: 461046  Cd Length: 67  Bit Score: 94.37  E-value: 1.70e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489910839  14 SASVAKERLQIILAHERGRGdSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQD-TLEVLEVKIEM 80
Cdd:pfam03776  1 SANVAKERLQLILAHDRADL-SPDYLEQLKNEILEVISKYVEIDEEKVEVQLEQDDgDVSVLEANIPL 67
minE TIGR01215
cell division topological specificity factor MinE; This protein is involved in the process of ...
 1-81 4.93e-27

cell division topological specificity factor MinE; This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division]


Pssm-ID: 188120  Cd Length: 81  Bit Score: 93.58  E-value: 4.93e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489910839   1 MSFLSFLLGQKKSSASVAKERLQIILAHERGrGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVLEVKIEM 80
Cdd:TIGR01215  1 MSLLEFFKSRKKNSAEVAKDRLKLILAHERA-QLAPEYLEELRKEILEVISKYVEIDPEMVEVSLESQGDMSVLELNITL 79


                 .
gi 489910839  81 P 81
Cdd:TIGR01215 80 P 80
PRK13988 PRK13988
cell division topological specificity factor MinE; Provisional
 3-74 5.66e-16

cell division topological specificity factor MinE; Provisional


Pssm-ID: 184441  Cd Length: 97  Bit Score: 66.33  E-value: 5.66e-16
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489910839  3 FLSFLLGQKKSSASVAKERLQIILAHERGrGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVL 74
Cdd:PRK13988  6 LLEKLFGRQPASASTARERLQLVLAHDRA-DLSPELLEQMRKEILEVVARYVEIDPEEGEVSLETEDRMTAL 76
PRK13987 PRK13987
cell division topological specificity factor MinE; Provisional
 1-65 3.76e-13

cell division topological specificity factor MinE; Provisional


Pssm-ID: 237579  Cd Length: 91  Bit Score: 58.91  E-value: 3.76e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489910839  1 MSFLSFLlGQKKSSASVAKERLQIILAHERGRGdSPDYLPQLQQELVAVISKYVKIDPEDIKVHL 65
Cdd:PRK13987  1 MDLFKFF-SKKPTSKDVAKERLKLILIHDRGDI-SPDVLEMIKEDILKVISKYVEIDNEDVDIKM 63
PRK13991 PRK13991
cell division topological specificity factor MinE; Provisional
 1-80 8.50e-12

cell division topological specificity factor MinE; Provisional


Pssm-ID: 172493  Cd Length: 87  Bit Score: 55.27  E-value: 8.50e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489910839  1 MSFLSFLLGQKK-SSASVAKERLQIILAHERGRgDSPDYLPQLQQELVAVISKYVK-IDPEDIKVHLERQDTLEVLEVKI 78
Cdd:PRK13991  1 MSFLDGLFGRKRdSSSELAKQRLLTVLVHDRVK-LTPEMMEQMKADLAEVIKRYVPaIDAEAIEVTLSRGEAHDHLKADI 79


                ..
gi 489910839 79 EM 80
Cdd:PRK13991 80 PL 81
PRK13990 PRK13990
cell division topological specificity factor MinE; Provisional
 6-83 3.55e-08

cell division topological specificity factor MinE; Provisional


Pssm-ID: 172492  Cd Length: 90  Bit Score: 46.27  E-value: 3.55e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489910839  6 FLLGQKKSSASVAKERLQIILAHERGR------GDSPDYLPQLQQELVAVISKYVKIDPEDIK-VHLERQDTLEVLEVKI 78
Cdd:PRK13990  6 FGLSKKQQSASVAKERLQIIVAHQRSElhprssKISSHLLAELKDEIIEVVKKYVALSEENIRdIDLKVEDSSKNSTIEV 85


                ....*
gi 489910839 79 EMPQN 83
Cdd:PRK13990 86 NIPFN 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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