|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
1-390 |
0e+00 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 691.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 1 MANEYAQDTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMA 80
Cdd:PRK08064 1 MAMSYSIDTLLLHNQYKHDKQTGAVNVPIYHASTFHQFDFDTFGKYDYSRSGNPTREALEDIIAELEGGTKGFAFASGMA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 81 AVSAALFTLSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTV 160
Cdd:PRK08064 81 AISTAFLLLSKGDHVLISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 161 AKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSW 240
Cdd:PRK08064 161 VKLAKAIGCLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKDEELAQKLYFLQNSFGAVLGVQDCW 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 241 LLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDLGSEEAVRELVTHLEL 320
Cdd:PRK08064 241 LVLRGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTLQSEEAVRQFVSHVKL 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 321 PVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALSFIKKGSVAK 390
Cdd:PRK08064 321 PVFAVSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYVEEPVNAK 390
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
8-381 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 561.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 8 DTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHA--------YDYARSGNPTREKVEQAIAELEGGTNGFAFASGM 79
Cdd:COG0626 4 ATRAVHAGRDPDPQTGAVSPPIYLTSTFVFPSAEALAArfageeggYIYSRYGNPTRRALEEALAALEGGEAALAFASGM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 80 AAVSAALFT-LSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIR 158
Cdd:COG0626 84 AAISAVLLAlLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVVDIA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 159 TVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQD 238
Cdd:COG0626 164 AIAAIAHAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNALGAVLSPFD 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 239 SWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTH 317
Cdd:COG0626 244 AWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELkGGREAARRFLDA 323
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489822298 318 LELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:COG0626 324 LKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQALA 387
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
8-380 |
0e+00 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 516.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 8 DTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALF 87
Cdd:pfam01053 1 DTLAVHAGQRPDPQTGAVSVPIYLTSTYVFDFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGMAAITAAIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 88 TLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKA 166
Cdd:pfam01053 81 ALLKaGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIEAIAKLAKK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 167 NGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGL 246
Cdd:pfam01053 161 HGILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATGAVLSPFDAWLLLRGL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 247 KTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDLGSE-EAVRELVTHLELPVFSV 325
Cdd:pfam01053 241 KTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKGGlEAAKKFLDNLKLFSLAV 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 489822298 326 SLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQAL 380
Cdd:pfam01053 321 SLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQAL 375
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
9-381 |
3.68e-170 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 479.99 E-value: 3.68e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 9 TAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFT 88
Cdd:PRK07671 5 TKLIHGGIIGDPSTGAVSVPIYQVSTYKQEAVGKHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAVMML 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 89 LSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANG 168
Cdd:PRK07671 85 FSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIAKEKG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 169 CYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKT 248
Cdd:PRK07671 165 LLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRGLKT 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 249 LSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDLGSEEAVRELVTHLELPVFSVSLG 328
Cdd:PRK07671 245 LGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDVGSEETANKVLERLQYFTLAESLG 324
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 489822298 329 AVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK07671 325 AVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
23-381 |
4.43e-169 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 477.08 E-value: 4.43e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 23 GALNTPIHLSSTFHQHDFDNYHA--------YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTL-SKGD 93
Cdd:cd00614 1 GAVAPPIYQTSTFVFPSPAEAADlfalreggYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLLALlKAGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 94 HFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFV 173
Cdd:cd00614 81 HVVASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHGALLVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 174 DNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKTLSVRM 253
Cdd:cd00614 161 DNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 254 KAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVES 332
Cdd:cd00614 241 ERHSENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELkGGLEAAKKFLNALKLFSLAVSLGGVES 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 489822298 333 ILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:cd00614 321 LVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
3-384 |
2.70e-148 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 424.11 E-value: 2.70e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 3 NEYAQDTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAV 82
Cdd:PRK08247 1 QMSTIETKLAQIGNRSDERTGTVNPPVYFSTAYRHEGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQGFACSSGMAAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 83 SAALFTLSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAK 162
Cdd:PRK08247 81 QLVMSLFRSGDELIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQETDIAAIAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 163 LAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLL 242
Cdd:PRK08247 161 IAKKHGLLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQELCERLAYYQNAAGAVLSPFDSWLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 243 LRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGlpshagydiqveqatsGGAVLSFDLGSEEAVRELVTHLELPV 322
Cdd:PRK08247 241 IRGMKTLALRMRQHEENAKAIAAFLNEQPGVTDVLYPG----------------RGGMLSFRLQDEEWVNPFLKSLKLIT 304
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489822298 323 FSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALSFIK 384
Cdd:PRK08247 305 FAESLGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAFKQVK 366
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
8-381 |
4.43e-147 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 422.13 E-value: 4.43e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 8 DTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHA-YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAAL 86
Cdd:PRK07811 14 ATRAIHAGYEPDPATGAVNPPIYASSTFAQDGVGGLRGgYEYARTGNPTRTALEEQLAALEGGAYGRAFSSGMAATDCLL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 87 FTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAK 165
Cdd:PRK07811 94 RAVLRpGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNPLLSITDIAALAELAH 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 166 ANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRG 245
Cdd:PRK07811 174 DAGAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNGAGAVPGPFDAYLTLRG 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 246 LKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFS 324
Cdd:PRK07811 254 LKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLaGGEEAARDFCARTKVFTLA 333
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489822298 325 VSLGAVESILSYPAKMSHA-------AVPEEerlaqgitpgLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK07811 334 ESLGGVESLIEHPSAMTHAstagsqlEVPDD----------LVRLSVGIEDVADLLADLEQALG 387
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
9-381 |
1.09e-146 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 420.84 E-value: 1.09e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 9 TAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFT 88
Cdd:PRK06176 5 TKLIHGGISEDTTTGAVSVPIYQTSTYRQDAIGRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHAVFSL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 89 LSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANG 168
Cdd:PRK06176 85 FQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKDHG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 169 CYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKT 248
Cdd:PRK06176 165 LLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQRGIKT 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 249 LSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDLGSEEAVRELVTHLELPVFSVSLG 328
Cdd:PRK06176 245 LGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFILGESLG 324
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 489822298 329 AVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK06176 325 GVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFA 377
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
23-380 |
2.80e-135 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 391.50 E-value: 2.80e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 23 GALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTLSKGDHFIIAKDVY 102
Cdd:TIGR01329 16 DASSMPIYQTATFKQPLAIENGPYDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAALDVITRLLNNGDEIIAGDDLY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 103 GGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLI 182
Cdd:TIGR01329 96 GGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRKISEMAHAQNALVVVDNTMMSPLL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 183 QKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEK 262
Cdd:TIGR01329 176 CNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTGSGLAPFDCWLLLRGIKTLAIRIEKQQENARA 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 263 IALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDLGSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSH 342
Cdd:TIGR01329 256 IAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKGAGSVLSFETGSVALSKRLVEATKLFSITVSFGSVNSLISMPCFMSH 335
|
330 340 350
....*....|....*....|....*....|....*...
gi 489822298 343 AAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQAL 380
Cdd:TIGR01329 336 ASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAF 373
|
|
| O_succ_thio_ly |
TIGR02080 |
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, ... |
7-380 |
5.92e-129 |
|
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 131135 Cd Length: 382 Bit Score: 375.68 E-value: 5.92e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 7 QDTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAAL 86
Cdd:TIGR02080 4 QATIAVRSGLNSDTQYGCVVPPIYLSTTYNFTGFNEPRAYDYSRSGNPTRDLLQQALAELEGGAGAVVTNTGMSAIHLVT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 87 FTLSKGDHFIIA-KDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAK 165
Cdd:TIGR02080 84 TALLGPDDLLVApHDCYGGTYRLLNALAKKGCFRVLFVDQGDEQALRAALAQKPKLVLIETPSNPLLRVVDIAKICHLAK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 166 ANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRG 245
Cdd:TIGR02080 164 AVGAVVVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVIAGAVIAKDPQVAEELAWWANNLGVTGGAFDSYLTLRG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 246 LKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFS 324
Cdd:TIGR02080 244 LRTLVARMRLQQRNAQAIVEYLQTQPLVKKIYYPGLPDHPGHEIAARQQKGFGAMLSFELkGGEQTVRRFLGGLSLFTLA 323
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 489822298 325 VSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQAL 380
Cdd:TIGR02080 324 ESLGGVESLIAHPATMTHAAMGPEARAEAGISDTLLRLSVGLEDADDLIADLEQGL 379
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
24-380 |
5.23e-128 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 376.29 E-value: 5.23e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 24 ALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTLSKGDHFIIAKDVYG 103
Cdd:PLN02509 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYG 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 104 GTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQ 183
Cdd:PLN02509 183 GSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHAQGALVLVDNSIMSPVLS 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 184 KPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKI 263
Cdd:PLN02509 263 RPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKI 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 264 ALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDLGSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHA 343
Cdd:PLN02509 343 AMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHA 422
|
330 340 350
....*....|....*....|....*....|....*..
gi 489822298 344 AVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQAL 380
Cdd:PLN02509 423 SIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
9-385 |
4.63e-127 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 371.47 E-value: 4.63e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 9 TAVIKASLGIDKETGALNTPIHLSSTFhqhDFDNYH-----------AYDYARSGNPTREKVEQAIAELEGGTNGFAFAS 77
Cdd:PRK06234 11 TKAIHGGHIGDKQFGSLATPIYQTSTF---IFDSAEqggrrfageesGYIYSRLGNPTSTEVENKLALLEGGEAAVVAAS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 78 GMAAVSAALFT-LSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTD 156
Cdd:PRK06234 88 GMGAISSSLWSaLKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVTD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 157 IRTVAKLAKAN--GCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNpNLAEAVYF--LQNSTGG 232
Cdd:PRK06234 168 IKAISNIAHENnkECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKE-EFINQVKLfgIKDMTGS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 233 VLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAV 311
Cdd:PRK06234 247 VIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELkGGVEEG 326
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489822298 312 RELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALSFIKK 385
Cdd:PRK06234 327 KVVMNNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQALDLIVK 400
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
3-380 |
1.94e-123 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 363.20 E-value: 1.94e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 3 NEYAQDTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDnyHAYD----------YARSGNPTREKVEQAIAELEGGTNG 72
Cdd:COG2873 4 KKYGFETLALHAGQEPDPTTGARAVPIYQTTSYVFDDAE--HAADlfalkepgniYTRIMNPTTDVLEKRIAALEGGVAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 73 FAFASGMAAVSAALFTL-SKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPL 151
Cdd:COG2873 82 LATASGQAAITLAILNLaEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 152 LHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIV-------TNN---PNLAE 221
Cdd:COG2873 162 LDVLDIEAIAEIAHEHGVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIVdggnfdwAANgkfPELTE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 222 -------AVYF---------------LQNSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYP 279
Cdd:COG2873 242 pdpsyhgLVYTeafgnaafitkarvqLLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWVNYP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 280 GLPSHAGYDIQVEQATSG-GAVLSFDL-GSEEAVRELVTHLELpvFS--VSLGAVESILSYPAKMSHAAVPEEERLAQGI 355
Cdd:COG2873 322 GLPSHPYHELAQKYLPKGaGGVLTFGLkGGREAGKKFIDSLKL--FShlANIGDAKSLVIHPASTTHSQLSEEEQAAAGV 399
|
410 420
....*....|....*....|....*
gi 489822298 356 TPGLLRFSAGLEDADDLIADLKQAL 380
Cdd:COG2873 400 TPDLIRLSVGIEDIDDIIADLDQAL 424
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
9-380 |
6.73e-121 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 355.35 E-value: 6.73e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 9 TAVIKASLGIDKETGALNTPIHLSSTFhqhDFDNYHA-----------YDYARSGNPTREKVEQAIAELEGGTNGFAFAS 77
Cdd:TIGR01328 6 TRAIHAGYPPKDQFGALTPPIYQTSTF---VFDSCEQggnrfagqesgYIYSRLGNPTVSNLEGRIAFLEGTEAAVATSS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 78 GMAAVSAALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTD 156
Cdd:TIGR01328 83 GMGAIAATLLTILKaGDHLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKLID 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 157 IRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEA-VYFLQNSTGGVLG 235
Cdd:TIGR01328 163 MERVCRDAHSQGVKVIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQIrMVGIKDMTGSVIS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 236 VQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVREL 314
Cdd:TIGR01328 243 PFDAWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMITFELkGGFAGAKKL 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489822298 315 VTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQAL 380
Cdd:TIGR01328 323 LNNLKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQAL 388
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
23-384 |
4.32e-118 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 348.65 E-value: 4.32e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 23 GALNTPIHLSSTFHQHDFDNYH--------AYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFT-LSKGD 93
Cdd:PRK08249 25 GATQVPVVLSVAYGYDDIDEWYdvalgkkpGHIYSRNTNPTVQAFEEKVRILEGAEAATAFSTGMAAISNTLYTfLKPGD 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 94 HFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFV 173
Cdd:PRK08249 105 RVVSIKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVDIERLAAAAKKVGALVVV 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 174 DNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGlIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKTLSVRM 253
Cdd:PRK08249 185 DNTFATPINQNPLALGADLVIHSATKFLSGHADALGG-VVCGSKELMEQVYHYREINGATMDPMSAYLILRGMKTLKLRV 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 254 KAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVES 332
Cdd:PRK08249 264 RQQQESAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLkGGMDTVKRLLPKLRYAHRAANLGAVET 343
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 489822298 333 ILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALSFIK 384
Cdd:PRK08249 344 IYGPARTTSHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFAHLE 395
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
8-383 |
1.98e-115 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 341.44 E-value: 1.98e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 8 DTAVIKASLGIDKETGALNTPIHLSSTFhqhDFDNYH-----------AYDYARSGNPTREKVEQAIAELEGGTNGFAFA 76
Cdd:PRK06767 7 ETALIHHGYTSEEHKGSLTPPLFQTSTF---TFETAQqgeasfagvdpSYIYSRLGNPTVKLFEERMAVLEGGEEALAFG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 77 SGMAAVSAALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVT 155
Cdd:PRK06767 84 SGMAAISATLIGFLKaGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMKLI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 156 DIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLG 235
Cdd:PRK06767 164 DLKQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDIGGIMA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 236 VQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPglpshaGYDIQVEQATSGGAVLSFDL-GSEEAVREL 314
Cdd:PRK06767 244 PFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWYP------EGELASRQMKRGGGVISFSIkGGKEETQAF 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489822298 315 VTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALSFI 383
Cdd:PRK06767 318 INDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALKKI 386
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
46-380 |
6.33e-115 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 339.90 E-value: 6.33e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 46 YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTL-SKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVD 124
Cdd:TIGR01325 46 FVYSRYGNPTVSVFEERLALLEGAEAAVATASGMAAIFAALMALlGAGDHVVASRSLFGSCFVVCSEILPRFGVQTVFVD 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 125 TTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGH 204
Cdd:TIGR01325 126 GTDLSAWEAALKPNTKAVFVETPSNPLQELVDIAAVAELAHAAGAKVVVDNVFATPLLQQPLKLGADVVVYSATKHIDGQ 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 205 SDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSH 284
Cdd:TIGR01325 206 GRVLGGAILGSEEYMDEPVQKLLRHTGPAMSPFNAWVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVYYPGLPSH 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 285 AGYDIQVEQATSGGAVLSFDLGSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSA 364
Cdd:TIGR01325 286 PQHELAKRQMSGGGTVVTFDLDCRQAAFKVLDAMRLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDGLVRLSV 365
|
330
....*....|....*.
gi 489822298 365 GLEDADDLIADLKQAL 380
Cdd:TIGR01325 366 GLEDVDDLIADIDRAL 381
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
7-386 |
2.41e-112 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 333.40 E-value: 2.41e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 7 QDTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAAL 86
Cdd:PRK08045 5 QATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 87 FT-LSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAK 165
Cdd:PRK08045 85 TVfLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 166 ANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRG 245
Cdd:PRK08045 165 EAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRG 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 246 LKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFS 324
Cdd:PRK08045 245 LRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELdGDEQTLRRFLGGLSLFTLA 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489822298 325 VSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALSFIKKG 386
Cdd:PRK08045 325 ESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG 386
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
1-381 |
4.54e-111 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 329.47 E-value: 4.54e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 1 MANEYAQDTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMA 80
Cdd:PRK07269 1 MSKDLHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGQSTGFDYTRTKNPTRAKLEETLAAIESADYALATSSGMS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 81 AVSAALFTLSKGDHFIIAKDVYGGTFRFVEQVLP--RFgithTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIR 158
Cdd:PRK07269 81 AIVLAFSVFPVGSKVVAVRDLYGGSFRWFNQQEKegRF----HFTYANTEEELIAAIEEDTDIVYIETPTNPLMVEFDIE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 159 TVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQD 238
Cdd:PRK07269 157 KVAKLAHAKGAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLELYEKLFYNLNTTGAVLSPFD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 239 SWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLpshagydiqveqatsgGAVLSFDLGSEEAVRELVTHL 318
Cdd:PRK07269 237 SYLLMRGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLYTGK----------------GGMISFKVADETRIPHILNSL 300
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489822298 319 ELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK07269 301 KVFTFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLKQALE 363
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
9-381 |
1.26e-109 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 326.64 E-value: 1.26e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 9 TAVIKASLGIDkETGALNTPIHLSSTFHQHD----FDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSA 84
Cdd:PRK08574 5 TDAVRGYRGSD-PYGSLQPPIYLTALFRQEGeaypSDRGFDLKYSREENPTLRPLEEALAKLEGGVDALAFNSGMAAIST 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 85 ALF-TLSKGDHFIIAKDVYGGTFRFVEQvLPRFG--ITHTFVDTTNIDEVAKAfqANTKLVYLETPSNPLLHVTDIRTVA 161
Cdd:PRK08574 84 LFFsLLKAGDRVVLPMEAYGTTLRLLKS-LEKFGvkVVLAYPSTEDIIEAIKE--GRTKLVFIETMTNPTLKVIDVPEVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 162 KLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWL 241
Cdd:PRK08574 161 KAAKELGAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVAWSGEFLEELWEWRRRLGTIMQPFEAYL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 242 LLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSG--GAVLSFDL-GSEEAVRELVTHL 318
Cdd:PRK08574 241 VLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKRLFGKDlyGGVVSFRVkGGRDAVLKFLRSL 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489822298 319 ELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK08574 321 KLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQALG 383
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
9-380 |
4.67e-109 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 325.79 E-value: 4.67e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 9 TAVIKAslGIDKET--GALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAAL 86
Cdd:PRK08776 15 TAAVRA--GIDRDTayGAVTPPIVLSSNFSFDGFGNKRQYDYTRSGNPTRDLLGEALAELEGGAGGVITATGMGAINLVL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 87 FTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAK 165
Cdd:PRK08776 93 NALLQpGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDLRFVIEAAH 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 166 ANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRG 245
Cdd:PRK08776 173 KVGALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWANALGLTGSPFDAFLTLRG 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 246 LKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFS 324
Cdd:PRK08776 253 LRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELeGGEAAVRAFVDGLRYFTLA 332
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 489822298 325 VSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQAL 380
Cdd:PRK08776 333 ESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGL 388
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
48-381 |
1.71e-107 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 321.18 E-value: 1.71e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 48 YARSGNPTREKVEQAIAELEGGTNGFAFASGMAAV-SAALFTLSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTT 126
Cdd:PRK08133 55 YSRFTNPTVTMFQERLAALEGAEACVATASGMAAIlAVVMALLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFVDLT 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 127 NIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSD 206
Cdd:PRK08133 135 DLDAWRAAVRPNTKLFFLETPSNPLTELADIAALAEIAHAAGALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGR 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 207 ILAGLIVTNNPNLAEAVYFLQnSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAG 286
Cdd:PRK08133 215 VLGGAVVGSKELMEEVFGFLR-TAGPTLSPFNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQ 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 287 YDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAG 365
Cdd:PRK08133 294 HELAKRQQKGGGAIVSFEVkGGREAAWRVIDATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVG 373
|
330
....*....|....*.
gi 489822298 366 LEDADDLIADLKQALS 381
Cdd:PRK08133 374 LEDVADIKADLARGLA 389
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
21-381 |
3.43e-106 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 318.28 E-value: 3.43e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 21 ETGALNTPIHLSSTFHqhdFDNYHA-----------YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFT- 88
Cdd:PRK07503 24 HGGALVPPVYLTATFA---FPTAEYgaecfageeegHFYSRISNPTLALLEQRMASLEGGEAAVALASGMGAITATLWTl 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 89 LSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANG 168
Cdd:PRK07503 101 LRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVDIAAVAEIAHGAG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 169 CYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEA-VYFLQNSTGGVLGVQDSWLLLRGLK 247
Cdd:PRK07503 181 AKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRIrLEGLKDMTGAVMSPFDAFLLMRGLK 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 248 TLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFSVS 326
Cdd:PRK07503 261 TLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELkGGIAAGRRFMNALQLFARAVS 340
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 489822298 327 LGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK07503 341 LGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALD 395
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
8-380 |
8.34e-102 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 307.75 E-value: 8.34e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 8 DTAVIKASLGIDKETGALNTPIHLSSTFhqhDFDNY-HA----------YDYARSGNPTREKVEQAIAELEGGTNGFAFA 76
Cdd:TIGR01326 3 ETLQLHAGQEPDPTTGSRAVPIYQTTSY---VFDSTeHAaalfglqepgNIYSRLMNPTTDVLEQRIAALEGGVAALAVA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 77 SGMAAVSAALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVT 155
Cdd:TIGR01326 80 SGQAAITYAILNLAGaGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 156 DIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVT--------------NNPN--- 218
Cdd:TIGR01326 160 DIEAIAEVAHRHGIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVDggkfdwnngrfplfTTPDpsy 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 219 --------LAEAVYFLQ------NSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSH 284
Cdd:TIGR01326 240 hglvftetLGNPAFILKarvqllRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGLASH 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 285 AGYDIQVEQATSG-GAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRF 362
Cdd:TIGR01326 320 PHHALAKKYLPKGfGAVLSFEIkGGREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGLIRL 399
|
410
....*....|....*...
gi 489822298 363 SAGLEDADDLIADLKQAL 380
Cdd:TIGR01326 400 SVGIENIDDIIADLEQAL 417
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
10-381 |
1.13e-100 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 303.74 E-value: 1.13e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 10 AVIKASLGIDKET--GALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALF 87
Cdd:PRK08861 7 ATIAVRTGIESDSqyHAVVPPIYLSTNYGFPAFGEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSALNLWVS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 88 TLSKGDHFIIA-KDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKA 166
Cdd:PRK08861 87 ALLGPDDLIVApHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDIAELCQKAKA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 167 NGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGL 246
Cdd:PRK08861 167 VGALVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTKEHAEELAWWGNCIGATGTPFDSYMTLRGI 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 247 KTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFSV 325
Cdd:PRK08861 247 RTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFaGSFEQLKVFVKALALFSLAE 326
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 489822298 326 SLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK08861 327 SLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQAFA 382
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
17-381 |
1.47e-100 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 302.91 E-value: 1.47e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 17 GIDKETGALNTPIHLSSTFHqhdFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTLSK-GDHF 95
Cdd:PRK06460 11 DIDEATGAITTPIYQTTAYH---YPEGEKYRYSREANPTVLELTKKIVELENAEMGVAFSSGMGAISTTALALLKpGNSV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 96 IIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDN 175
Cdd:PRK06460 88 LVHRDMFGRSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKSKRYDVVFVENITNPLLRVVDITELSKVCKENGSILIVDA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 176 TFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNpNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKTLSVRMKA 255
Cdd:PRK06460 168 TFSTPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYG-KLLNVIDQMRRTLGTSLDPHAAYLTLRGIKTLKIRMDV 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 256 GTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVESIL 334
Cdd:PRK06460 247 INRNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVnGGQESALKVMKSLKLIIPAQTLGGVNSVI 326
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 489822298 335 SYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK06460 327 SHPATMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRALS 373
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
28-381 |
7.60e-97 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 293.06 E-value: 7.60e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 28 PIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTnGFAFASGMAAVSAALFTLSK-GDHFIIAKDVYGGTF 106
Cdd:PRK07582 25 GPVFAAPYHLSPGEPTGPDTYGRASNPTWRALEAALGELEGAE-ALVFPSGMAAITAVLRALLRpGDTVVVPADGYYQVR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 107 RFVEQVLPRFGIThtfVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQKPL 186
Cdd:PRK07582 104 ALAREYLAPLGVT---VREAPTAGMAEAALAGADLVLAETPSNPGLDVCDLAALAAAAHAAGALLVVDNTTATPLGQRPL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 187 ELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALF 266
Cdd:PRK07582 181 ELGADLVVASDTKALTGHSDLLLGYVAGRDPELMAAVERWRLLAGAIPGPFEAWLAHRSLGTLGLRFARQCANALAVAEL 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 267 LNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDLGSEEAVRELVTHLELPVFSVSLGAVesilsypakmsHAAVP 346
Cdd:PRK07582 261 LAGHPAVRGVRYPGLPGDPAHEVAARQMRRFGGLVSFELADAAAAERFVAASRLVVAATSFGGV-----------HTSAD 329
|
330 340 350
....*....|....*....|....*....|....*
gi 489822298 347 EEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK07582 330 RRARWGDAVPEGFVRLSCGIEDTDDLVADLERALD 364
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
46-380 |
1.85e-94 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 288.19 E-value: 1.85e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 46 YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFT-LSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVD 124
Cdd:PRK07504 57 FIYSRYSNPTVDMFEKRMCALEGAEDARATASGMAAVTAAILCqVKAGDHVVAARALFGSCRYVVETLLPRYGIESTLVD 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 125 TTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGH 204
Cdd:PRK07504 137 GLDLDNWEKAVRPNTKVFFLESPTNPTLEVIDIAAVAKIANQAGAKLVVDNVFATPLFQKPLELGAHIVVYSATKHIDGQ 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 205 SDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSH 284
Cdd:PRK07504 217 GRCLGGVVLSDKAWIEEHLQDYFRHTGPSLSPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVIYPGRADH 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 285 AGYDIQVEQATSGGAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFS 363
Cdd:PRK07504 297 PQADIIAKQMTGGSTLVAFELkGGKEAAFRFLNALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGISEGFLRLS 376
|
330
....*....|....*..
gi 489822298 364 AGLEDADDLIADLKQAL 380
Cdd:PRK07504 377 AGLEDTDDLIEDLAAAL 393
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
1-387 |
2.45e-92 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 283.95 E-value: 2.45e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 1 MANEYAQDTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDnyHAYD----------YARSGNPTREKVEQAIAELEGGT 70
Cdd:PRK07812 8 PTANWSFETKQIHAGQTPDPATNARALPIYQTTSYTFDDTD--HAAAlfglaepgniYTRIMNPTQDVVEQRIAALEGGV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 71 NGFAFASGMAAVSAALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFV-DTTNIDEVAKAFQANTKLVYLETPS 148
Cdd:PRK07812 86 AALLLASGQAAETFAILNLAGaGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFVeDPDDLDAWRAAVRPNTKAFFAETIS 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 149 NPLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIV--------------- 213
Cdd:PRK07812 166 NPQIDVLDIPGVAEVAHEAGVPLIVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIVdggtfdwtqgrfpgf 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 214 -TNNPNLAEAVYF--------------LQNSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHY 278
Cdd:PRK07812 246 tTPDPSYHGVVFAelgppayalkarvqLLRDLGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNY 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 279 PGLPSHAGYDIQVEQATSG-GAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGIT 356
Cdd:PRK07812 326 AGLPSSPWYERAKRLAPKGtGAVLSFELaGGVEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVT 405
|
410 420 430
....*....|....*....|....*....|.
gi 489822298 357 PGLLRFSAGLEDADDLIADLKQALSFIKKGS 387
Cdd:PRK07812 406 PGLVRLAVGIEGIDDILADLEAGFAAAKAFS 436
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
19-381 |
5.12e-90 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 276.40 E-value: 5.12e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 19 DKETGALNTPIHLSSTF--------HQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTL- 89
Cdd:PRK06434 21 DPRFGNVTTPIFETSTFvypnsekeAYMDSTRGMPYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSGMGAITSAILSLi 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 90 SKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAkaFQA-NTKLVYLETPSNPLLHVTDIRTVAKLAKANg 168
Cdd:PRK06434 101 KKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDTDRLNSLD--FDPsNYDLIYAESITNPTLKVPDIKNVSSFCHEN- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 169 cYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKT 248
Cdd:PRK06434 178 -DVIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERRKTLGSNPDPIQAYLALRGLKT 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 249 LSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLpshagyDIQVEQATSGGAVLSFDLGSEEAVRELVTHLELPVFSVSLG 328
Cdd:PRK06434 257 LGLRMEKHNKNGMELARFLRDSKKISNVYYPDT------EIGKKVLRGFGGMLSFELRSMEDVHKFIRNLEIPMVAASLG 330
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 489822298 329 AVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK06434 331 GVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENALS 383
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
8-386 |
3.04e-87 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 270.84 E-value: 3.04e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 8 DTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDnyHA----------YDYARSGNPTREKVEQAIAELEGGTNGFAFAS 77
Cdd:PRK08134 10 DTLALHAGAAPDPATGARAVPIHLTTSFVFRDSD--HAaalfnleragHVYSRISNPTVAVLEERVAALEGGVGAIATAS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 78 GMAAVSAALFTL-SKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTD 156
Cdd:PRK08134 88 GQAALHLAIATLmGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 157 IRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNN----------PNLAEA---- 222
Cdd:PRK08134 168 IPTVAAIAHEAGVPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLVDGGrfdweasgkfPELTEPyagf 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 223 --VYFLQNST----------------GGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSH 284
Cdd:PRK08134 248 hgMVFAEESTvaafllrarreglrdfGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELESH 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 285 AGYDIQVEQATSG-GAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRF 362
Cdd:PRK08134 328 PDHALAKRLLPRGaGSVFSFDLkGGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIGEGTIRL 407
|
410 420
....*....|....*....|....
gi 489822298 363 SAGLEDADDLIADLKQALSFIKKG 386
Cdd:PRK08134 408 SIGLEDADDLIDDLKRALKAAEKA 431
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
46-381 |
1.35e-86 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 268.14 E-value: 1.35e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 46 YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVD 124
Cdd:PRK07810 62 FVYSRYGNPTVSMFEERLRLIEGAEACFATASGMSAVFTALGALLGaGDRLVAARSLFGSCFVVCNEILPRWGVETVFVD 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 125 TTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGH 204
Cdd:PRK07810 142 GEDLSQWEEALSVPTQAVFFETPSNPMQSLVDIAAVSELAHAAGAKVVLDNVFATPLLQRGLPLGADVVVYSGTKHIDGQ 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 205 SDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSH 284
Cdd:PRK07810 222 GRVLGGAILGDREYIDGPVQKLMRHTGPALSAFNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLPSH 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 285 AGYDIQVEQATSGGAVLSFDL-GSEEAVR----ELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGL 359
Cdd:PRK07810 302 PQYDLAKRQMSGGGTVVTFELdAPEDAAKkrafEVLDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLGDGV 381
|
330 340
....*....|....*....|..
gi 489822298 360 LRFSAGLEDADDLIADLKQALS 381
Cdd:PRK07810 382 VRLSVGLEDTDDLIADLDRALG 403
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
23-381 |
1.35e-82 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 257.32 E-value: 1.35e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 23 GALNTPIHLSSTFhqhDFDNY-----------HAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTL-S 90
Cdd:PRK05968 24 DAVVPPIFQTSLF---TFDSYdemedvyagekVRPIYSRGDNPTVRAFEEMLAKLEGAEDARGFASGMAAISSTVLSFvE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 91 KGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQAnTKLVYLETPSNPLLHVTDIRTVAKLAKANGCY 170
Cdd:PRK05968 101 PGDRIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKALPG-AKLLYLESPTSWVFELQDVAALAALAKRHGVV 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 171 TFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNnpnlAEAVYFLQNST----GGVLGVQDSWLLLRGL 246
Cdd:PRK05968 180 TMIDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGS----KEHIARINAEAypylGAKLSPFEAWLLLRGL 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 247 KTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSH--AGYdiqveQATSGgaVLSFDLGSEEAVRELVTHLELPVFS 324
Cdd:PRK05968 256 RTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHppAGL-----SGTSG--LFSFIFREGIDVRAFADALKLFRLG 328
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 489822298 325 VSLGAVESiLSYPAKMSHAAVPEEERLAQ-GITPGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK05968 329 VSWGGHES-LVVPAEVVLQQKAQPNSAARfGVSPRSVRLHVGLEGTEALWADLEQALA 385
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
23-380 |
9.56e-81 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 253.83 E-value: 9.56e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 23 GALNTPIHLSSTFHQH------DFDNYHA------------YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSA 84
Cdd:PRK07049 34 GAVKPPVFLTSTFVFRsaedgrDFFDYVSgrkeppagegagLVYSRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIAT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 85 ALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGIT-HTFVDTTNIDEVAKAFQA-----NTKLVYLETPSNP---LLHV 154
Cdd:PRK07049 114 TLLAFVRpGDVILHSQPLYGGTETLLAKTFRNFGVGaVGFADGLSEAAIGAAAEAaaakgRVSLILIETPANPtnsLVDV 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 155 TDIRTVAKLAKANGCYTFV---DNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGlIVTNNPNLAEAVYFLQNSTG 231
Cdd:PRK07049 194 AAVRRVADAIEARQGHRPIiacDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAG-AVLGRKALIRQVRALRSAIG 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 232 GVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGL--PSHAGYDIQVEQATSGGAVLSFDL--GS 307
Cdd:PRK07049 273 TQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYLPFldPDSAYGAVYKRQCTGAGSTFSFDIkgGQ 352
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489822298 308 EEAVRELvTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQAL 380
Cdd:PRK07049 353 AAAFRFL-NALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHPDDLIADLAQAL 424
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
3-380 |
9.91e-81 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 254.00 E-value: 9.91e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 3 NEYAQDTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDnyHA----------YDYARSGNPTREKVEQAIAELEGGTNG 72
Cdd:PRK08248 5 RTFRLETLAIHAGQEIDPTTGSRAVPIYQTTSYGFRDSE--HAanlfslkefgNIYTRIMNPTTDVFEKRIAALEGGIGA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 73 FAFASGMAAVSAALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPL 151
Cdd:PRK08248 83 LAVSSGQAAITYSILNIASaGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNPK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 152 LHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIV-----------------T 214
Cdd:PRK08248 163 GDVLDIEAVAAIAHEHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVdsgkfdwkgsgkfpgltE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 215 NNPN---------LAEAVYFLQ------NSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYP 279
Cdd:PRK08248 243 PDPSyhglvytdaVGEAAYITKarvqllRDLGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSYP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 280 GLPSHAGYDIQVEQATSG-GAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITP 357
Cdd:PRK08248 323 GLPSHPSYELAKKYLPKGqGAILTFGIkGGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVTP 402
|
410 420
....*....|....*....|...
gi 489822298 358 GLLRFSAGLEDADDLIADLKQAL 380
Cdd:PRK08248 403 GLVRLSVGTEAIDDILDDLRQAI 425
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
21-383 |
6.88e-78 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 245.75 E-value: 6.88e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 21 ETGALNTPIHLSSTFHQHD-------FDNYHA-YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTLSK- 91
Cdd:PRK05939 6 EHGAVHKPIHTSVTYGYEDardlidvFQGKKPgFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFLTLLRa 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 92 GDHFIIAKDVYGGTfRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYT 171
Cdd:PRK05939 86 GDHLVSSQFLFGNT-NSLFGTLRGLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERGLLY 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 172 FVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIV-------TNNPNLAEAvY---------FLQ------NS 229
Cdd:PRK05939 165 VVDNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTdtglfdwSAYPNIFPA-YrkgdpqqwgLTQirkkglRD 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 230 TGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDLGSEE 309
Cdd:PRK05939 244 MGATLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFELADGI 323
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489822298 310 AVRELVTHLELPVFSVSLGAVESiLSYPAkmSHAAVPE---EERLAQGITPGLLRFSAGLEDADDLIADLKQALSFI 383
Cdd:PRK05939 324 DCFDFLNRLKLVIKATHLGDTRT-LVIPV--APTIYYEmgaERRASMGIADSLIRVSVGIEDEADLIADFEQALDAT 397
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
8-381 |
5.93e-77 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 244.24 E-value: 5.93e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 8 DTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDnyHAYD----------YARSGNPTREKVEQAIAELEGGTNGFAFAS 77
Cdd:PRK05994 9 ATLAVHAGAQPDPTTGARATPIYQTTSFVFNDAD--HAASlfglqafgniYTRITNPTNAVLEERVAALEGGTAALAVAS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 78 GMAAVSAALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTD 156
Cdd:PRK05994 87 GHAAQFLVFHTLLQpGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVTD 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 157 IRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVT----------NNPNLAE--AVY 224
Cdd:PRK05994 167 IAAIAEVAHRAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIIVDggtfdwsksgKYPMLSEprPEY 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 225 ---FLQNSTGG--------VLGVQD---------SWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSH 284
Cdd:PRK05994 247 hglVLHETFGNfafaiaarVLGLRDlgpaispfnAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGLPDD 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 285 AGYDIQVEQATSG-GAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRF 362
Cdd:PRK05994 327 PYHALAQKYSPKGaGAVFTFGLkGGYEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVVRL 406
|
410
....*....|....*....
gi 489822298 363 SAGLEDADDLIADLKQALS 381
Cdd:PRK05994 407 SIGIEDVDDIIADLEQALA 425
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
2-383 |
4.38e-72 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 231.68 E-value: 4.38e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 2 ANEYAQDTAVIKASLGIDKETGALNTPIHLSSTF----HQHDFDNYHAYD----YARSGNPTREKVEQAIAELEGGTNGF 73
Cdd:PRK05613 9 ADQWGFETRSIHAGQSVDSDTSARNLPIYQTTSYvfdsAEHAKQRFALEDlgpiYSRLTNPTVEALENRIASLEGGVHAV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 74 AFASGMAAVSAALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDttNIDEVAK---AFQANTKLVYLETPSN 149
Cdd:PRK05613 89 AFASGQAAETAAILNLAGaGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVE--NPDDPESwqaAVQPNTKAFFGETFAN 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 150 PLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLI----------------- 212
Cdd:PRK05613 167 PQADVLDIPAVAEVAHRNQVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLidggkfdwtverdgkpv 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 213 ----VTNNP--------NLAEAVYFLQ------NSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVV 274
Cdd:PRK05613 247 fpyfVTPDPayhglkyaDLGAPAFGLKaragllRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVA 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 275 AVHYPGLPSHAGYDIQVEQATS-GGAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLA 352
Cdd:PRK05613 327 KVNFAGLKDSPWYATKEKLGLKyTGSVLSFDIkGGKDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLAR 406
|
410 420 430
....*....|....*....|....*....|.
gi 489822298 353 QGITPGLLRFSAGLEDADDLIADLKQALSFI 383
Cdd:PRK05613 407 AGITQATVRLSVGIEDIDDIIADLEGGFAAI 437
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
8-381 |
2.03e-71 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 229.79 E-value: 2.03e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 8 DTAVIKASLGIDKETGALNTPIHLSSTFHqhdFDN-YHAYD----------YARSGNPTREKVEQAIAELEGGTNGFAFA 76
Cdd:PRK06084 4 ETLAIHAGYSPDPTTKAVAVPIYQTTSYA---FDDtQHGADlfdlkvpgniYTRIMNPTNDVLEQRVAALEGGVGALAVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 77 SGMAAVSAALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVT 155
Cdd:PRK06084 81 SGMAAITYAIQTIAEaGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNII 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 156 DIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIV------------------TNNP 217
Cdd:PRK06084 161 DIQALADAAHRHGVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVdsgkfpwaehkerfallnTPDP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 218 NLAEAVYFLQ---------------NSTGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLP 282
Cdd:PRK06084 241 SYHGVTYTEAfgpaafigrcrvvplRNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 283 SHAGYDIQVeQATSG--GAVLSFDL-GSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGL 359
Cdd:PRK06084 321 DHPEHELAR-RYMGGkpASILSFGIkGGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAGVSRDM 399
|
410 420
....*....|....*....|..
gi 489822298 360 LRFSAGLEDADDLIADLKQALS 381
Cdd:PRK06084 400 VRLSIGIEHIDDIIADLAQALD 421
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
23-380 |
1.45e-69 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 223.60 E-value: 1.45e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 23 GALNTPIHLSSTFHqhdFDNYHA-------YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFT-LSKGDH 94
Cdd:TIGR01324 15 GSVNPPLQRASTVL---FDSHAAqrrakgeLTYGRRGTLTHFALQDAMCELEGGAGCYLYPSGLAAVTNSILAfVKAGDH 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 95 FIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVD 174
Cdd:TIGR01324 92 VLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITFEIQDIPAIAKAARNPGIVIMID 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 175 NTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNN---PNLAEAVYFLqnstGGVLGVQDSWLLLRGLKTLSV 251
Cdd:TIGR01324 172 NTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIGTVVANArtwDQLREHSYLM----GQMVDADDAYTTLRGLRTLGV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 252 RMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL--GSEEAVRELVTHLELPVFSVSLGA 329
Cdd:TIGR01324 248 RLKQHQESSLAIAKWLSEQPEVARVLHPALPSCPGHEFWKRDFSGSSGLFSFVLqrLTQKQVHAFLDHLQLFGLGYSWGG 327
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 489822298 330 VES-ILSYPAKMSHAAVpeeerLAQGITPGLLRFSAGLEDADDLIADLKQAL 380
Cdd:TIGR01324 328 YESlALCNQPELGHRPN-----IKRNLEGPLIRVHIGLENVDDLKADLKAGF 374
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
6-384 |
1.50e-63 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 209.24 E-value: 1.50e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 6 AQDTAVIKASLGidkETGALNTPIHLSSTFHQHDFDNYHA------------YDYARSGNPTREKVEQAIAELEGGTNGF 73
Cdd:PLN02242 19 AAALASARHEFG---EHGGVNMSIEASATFTVMEPDTMRRmfsgelgpdrdfYIYSRHFNPTVLNLGRQMAALEGTEAAY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 74 AFASGMAAVSAALFTL-SKGDHFIIAKDVYGGTFRFVEQVLPR-FGITHTFVDTTNIDEVAKAFQAN-TKLVYLETPSNP 150
Cdd:PLN02242 96 CTASGMSAISSVLLQLcSSGGHVVASNTLYGGTHALLAHFLPRkCNITTTFVDITDLEAVKKAVVPGkTKVLYFESISNP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 151 LLHVTDIRTVAKLAKANGCYTFVDNTFlTPLIQKPLELGADLVIHSATKFLGGHSDILAGlivtnnpnlaeAVYFLQNST 230
Cdd:PLN02242 176 TLTVADIPELARIAHEKGVTVVVDNTF-APMVLSPARLGADVVVHSISKFISGGADIIAG-----------AVCGPAELV 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 231 GGVLGVQDSWLLLRG--------------LKTLSVRMKAGTETAEKIALFLnaEPDVVAVHYPGLPSHAGYDIQVEQATS 296
Cdd:PLN02242 244 NSMMDLHHGALMLLGptmnpkvafelserLPHLSLRMKEHCRRAMEYAKRM--KELGLKVIYPGLEDHPQHALLKSMANK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 297 G---GAVLSFDLGSEEAVRELVTHLE----LPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAG-LED 368
Cdd:PLN02242 322 GygfGGLLCLDMDTEERANRLMRYLQnstqFGFMAVSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVGyTGT 401
|
410
....*....|....*.
gi 489822298 369 ADDLIADLKQALSFIK 384
Cdd:PLN02242 402 LEQRWSQFEKALSAMK 417
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
46-381 |
3.15e-63 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 207.74 E-value: 3.15e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 46 YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFT-LSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVD 124
Cdd:PRK05967 56 YTYGTRGTPTTDALCKAIDALEGSAGTILVPSGLAAVTVPFLGfLSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYD 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 125 TTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGH 204
Cdd:PRK05967 136 PEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIPAIAEAAHRHGAIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGH 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 205 SDILAGLIVTNN---PNLAEAvyflqNSTGGVLGV-QDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPG 280
Cdd:PRK05967 216 SDILLGTVSANEkcwPQLLEA-----HGTLGLCAGpDDTYQILRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPA 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 281 LPSHAGYDIQVEQATSGGAVLSFDLGSEEAVRELVTHLELPVFSV-----SLGAVESiLSYPAKMShaavpeEERLAQGI 355
Cdd:PRK05967 291 LPSFPGHEIWKRDFSGASGIFSFVLAAGPEKGKAKAHAFLDALEIfglgySWGGYES-LALHVKLG------DRTVAKAP 363
|
330 340
....*....|....*....|....*..
gi 489822298 356 TPG-LLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK05967 364 YAGpVIRLQIGLEDVPDLKADLERGFA 390
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
24-380 |
2.40e-59 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 197.25 E-value: 2.40e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 24 ALNTPIHLSST--------FHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTLSK-GDH 94
Cdd:PRK07050 27 SFVTPVARASTvvfpdlatMRALDWRQDVQWRYGLHATPTSLALAQRLAEIEGGRHALLQPSGLAAISLVYFGLVKaGDD 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 95 FIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVD 174
Cdd:PRK07050 107 VLIPDNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEVPDVPAITAAARARGVVTAID 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 175 NTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSWLLLRGLKTLSVRMK 254
Cdd:PRK07050 187 NTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARMRLGIGVSADDCSLVLRGLPSLQVRLA 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 255 AGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDLGSE---EAVRELVTHLELPVFSVSLGAVE 331
Cdd:PRK07050 267 AHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSVVFDERyspAQVDAFVEALELFAIGWSWGGAC 346
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 489822298 332 SI-LSYP-AKMSHAAVPEEERlaqgitpgLLRFSAGLEDADDLIADLKQAL 380
Cdd:PRK07050 347 SLaMPYDvASMRTAKWPHRGT--------LVRLYIGLEDEADLIADLEQAL 389
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
7-381 |
4.43e-56 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 188.79 E-value: 4.43e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 7 QDTAVIkaSLGIDKE--TGALNTPIHLSST--FHQHDFDNYHAYD-------YARSGNPTREKVEQAIAELEGGTNGFAF 75
Cdd:PRK09028 5 KATKIV--SAGRDKKwtKGVINPPVFRASTvvFDTVAEMRHAAKNrangemfYGRRGTPTHFAFQAAIVELEGGAGTALY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 76 ASGMAAVSAALFTLSK-GDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHV 154
Cdd:PRK09028 83 PSGAAAISNALLSFLKaGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITMEV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 155 TDIRTVAKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNN---PNLAEAVYFLqnstG 231
Cdd:PRK09028 163 QDVPTLSRIAHEHDIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLGTATANEkhwDQLREHSYLM----G 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 232 GVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDL--GSEE 309
Cdd:PRK09028 239 QCTSPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLkqGDPK 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489822298 310 AVRELVTHLELPVFSVSLGAVES-ILSYPA--KMSHAAVPEEERlaqgitpGLLRFSAGLEDADDLIADLKQALS 381
Cdd:PRK09028 319 AVTALVEGMQHFKMGFSWGGFESlILGVFGinKLRTATNWDFSK-------PLIRLHIGLEDVDDLIADLEAGFE 386
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
48-384 |
8.30e-53 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 180.28 E-value: 8.30e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 48 YARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFT-LSKGDHFIIAKDVYGGTFRFVEQVLPRFGITHTFVDTT 126
Cdd:PRK08114 56 YGRRGTLTHFSLQEAMCELEGGAGCALYPCGAAAVANAILAfVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 127 NIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLA--KANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGH 204
Cdd:PRK08114 136 IGADIAKLIQPNTKVVFLESPGSITMEVHDVPAIVAAVrsVNPDAVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGH 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 205 SDILAGLIVTNN---PNLAEAVYFLqnstGGVLGVQDSWLLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGL 281
Cdd:PRK08114 216 SDAMIGTAVANArcwEQLRENSYLM----GQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPAL 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 282 PSHAGYDIQVEQATSGGAVLSFDLG---SEEAVRELVTHLELPVFSVSLGAVES-ILSYPAKMSHAAVPEEERlaqGITP 357
Cdd:PRK08114 292 PGCKGHEFWKRDFTGSSGLFSFVLKkklTDEQLANYLDNFSLFSMAYSWGGFESlILANQPEEIAAIRPAGEV---DFTG 368
|
330 340
....*....|....*....|....*..
gi 489822298 358 GLLRFSAGLEDADDLIADLKQALSFIK 384
Cdd:PRK08114 369 TLIRLHIGLEDVDDLIADLAAGFARIV 395
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
28-380 |
2.35e-52 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 180.25 E-value: 2.35e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 28 PIHLSSTFHQHDFDNYHA--------YDYARSGNPTREKVEQAIAELEGGTNGFAFASGMAAVSAALFTL-SKGDHFIIA 98
Cdd:PRK06702 27 PLYQSTTYKYDTSDDLAAlfnleaegYIYTRIGNPTLAAFEQKLAELEGGVGAVATASGQAAIMLAVLNIcSSGDHLLCS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 99 KDVYGGTFRFVEQVLPRFGITHTFVDTT-NIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDNTF 177
Cdd:PRK06702 107 STVYGGTFNLFGVSLRKLGIDVTFFNPNlTADEIVALANDKTKLVYAESLGNPAMNVLNFKEFSDAAKELEVPFIVDNTL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 178 LTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIV-------TNN--PNLAE------AVYFLQNSTGGVLGVQDSWLL 242
Cdd:PRK06702 187 ATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdggnfdwTNGkyPELVEpdpsyhGVSYVQNFGAAAYIVKARVQL 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 243 LR----------------GLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGA-VLSFDL 305
Cdd:PRK06702 267 LRdygncmspfnayisniGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSNENYSLAQKYLKKGASgVLTFGI 346
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489822298 306 -GSEEAVRELVTHLELPVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQAL 380
Cdd:PRK06702 347 kGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIRLSVGIEDVSDIIADLEAAL 422
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
61-223 |
6.80e-07 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 50.80 E-value: 6.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 61 QAIAELEGGTNGFA--------FASGMAAVSAAL-FTLSKGDHFIIAKDVYGGTFRFVEQvlprFGITHTFVDTT----- 126
Cdd:cd00609 43 EAIAEWLGRRGGVDvppeeivvTNGAQEALSLLLrALLNPGDEVLVPDPTYPGYEAAARL----AGAEVVPVPLDeeggf 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 127 --NIDEVAKAFQANTKLVYLETPSNP---LLHVTDIRTVAKLAKANGCYTFVDNTFL----TPLIQKPLELGAD----LV 193
Cdd:cd00609 119 llDLELLEAAKTPKTKLLYLNNPNNPtgaVLSEEELEELAELAKKHGILIISDEAYAelvyDGEPPPALALLDAyervIV 198
|
170 180 190
....*....|....*....|....*....|....
gi 489822298 194 IHSATKFLGghsdiLAGL----IVTNNPNLAEAV 223
Cdd:cd00609 199 LRSFSKTFG-----LPGLrigyLIAPPEELLERL 227
|
|
| YnbB |
COG4100 |
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion ... |
35-203 |
8.48e-07 |
|
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 443276 Cd Length: 409 Bit Score: 50.49 E-value: 8.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 35 FHQHDFDNYH-----AYDYARSGnptREKVEQAIAELEGGTNGF---AFASGMAAVSAALF-TLSKGDHFIIA------- 98
Cdd:COG4100 36 FQKNRVSDSHfagttGYGYDDIG---RDTLERVYADVFGAEDALvrpQIVSGTHAIALALFgVLRPGDELLSItgkpydt 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 99 -KDVYG------GTfrfveqvLPRFGITHTFVDTT-----NIDEVAKAFQANTKLV-------YLETPSnplLHVTDIRT 159
Cdd:COG4100 113 lEEVIGirgegqGS-------LKEFGISYRQVPLTedgkiDLEAIKKAINEKTKMVliqrsrgYSWRPS---LTIEEIGE 182
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 489822298 160 VAKLAKAN--GCYTFVDNT---FLTplIQKPLELGADLVIHSATKFLGG 203
Cdd:COG4100 183 IIKFVKSInpDVICFVDNCygeFVE--TREPTEVGADLMAGSLIKNPGG 229
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
56-203 |
1.12e-06 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 48.15 E-value: 1.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 56 REKVEQAIAELEGGTN--GFAFASGMAAVSAALFTL-SKGDHFIIAKDVYGGTfRFVEQVLPRFGITHTFVD-----TTN 127
Cdd:cd01494 2 LEELEEKLARLLQPGNdkAVFVPSGTGANEAALLALlGPGDEVIVDANGHGSR-YWVAAELAGAKPVPVPVDdagygGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 128 IDEV-AKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVDNTFLTPLI----QKPLELGADLVIHSATKFLG 202
Cdd:cd01494 81 VAILeELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGASpapgVLIPEGGADVVTFSLHKNLG 160
|
.
gi 489822298 203 G 203
Cdd:cd01494 161 G 161
|
|
| SelA |
COG1921 |
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis]; |
57-213 |
1.24e-04 |
|
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441524 Cd Length: 399 Bit Score: 43.96 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 57 EKVEQAIAELEGGTNGFAFASGMAAVSAALFTLSKGDHFIIAK--DV-YGGTFRfVEQVLPRFGITHTFVDTTN---IDE 130
Cdd:COG1921 68 DHVEELLCELTGAEAALVVNNNAAAVLLALAALAAGKEVIVSRgeLVeIGGSFR-IPDVMALSGAKLVEVGTTNrthLRD 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 131 VAKAFQANTKLvyletpsnpLLHV-------------TDIRTVAKLAKANG--CY------TFVDNTFL----TPLIQKP 185
Cdd:COG1921 147 YEAAITENTAA---------LLKVhtsnyrivgfteeVSLAELAELAHEHGlpVIvdlgsgSLVDLSKYglphEPTVQEY 217
|
170 180
....*....|....*....|....*...
gi 489822298 186 LELGADLVIHSATKFLGGHSdilAGLIV 213
Cdd:COG1921 218 LAAGADLVTFSGDKLLGGPQ---AGIIV 242
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
2-174 |
3.08e-04 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 42.29 E-value: 3.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 2 ANEYAQDT--AVIKASlgidKETGAlNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAeleggtngfaFASGM 79
Cdd:pfam00155 8 SNEYLGDTlpAVAKAE----KDALA-GGTRNLYGPTDGHPELREALAKFLGRSPVLKLDREAAVV----------FGSGA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 80 AAVSAALFTLS--KGDHFIIAKDVY----------GGTFRFVE-QVLPRFGIThtfvdttnIDEVAKAFQANTKLVYLET 146
Cdd:pfam00155 73 GANIEALIFLLanPGDAILVPAPTYasyiriarlaGGEVVRYPlYDSNDFHLD--------FDALEAALKEKPKVVLHTS 144
|
170 180 190
....*....|....*....|....*....|.
gi 489822298 147 PSNP---LLHVTDIRTVAKLAKANGCYTFVD 174
Cdd:pfam00155 145 PHNPtgtVATLEELEKLLDLAKEHNILLLVD 175
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
41-175 |
2.75e-03 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 39.34 E-value: 2.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 41 DNYHAYDYARsGNP-TREkveqAIAELEGGTNGFAF--------ASGMAAVSAALFTL-SKGDHFIIAK---DVYGGTFR 107
Cdd:COG0436 58 DGVTGYTPSA-GIPeLRE----AIAAYYKRRYGVDLdpdeilvtNGAKEALALALLALlNPGDEVLVPDpgyPSYRAAVR 132
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489822298 108 FveqvlprFGITHTFVDTT-------NIDEVAKAFQANTKLVYLETPSNP---LLHVTDIRTVAKLAKANGCYTFVDN 175
Cdd:COG0436 133 L-------AGGKPVPVPLDeengflpDPEALEAAITPRTKAIVLNSPNNPtgaVYSREELEALAELAREHDLLVISDE 203
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
35-174 |
2.84e-03 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 39.35 E-value: 2.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489822298 35 FHQHDFDNYHAYDYARSGNPT--REKVEQAIAELEGG--TNGFAFASGM----AAVSAALFTLSKGDHFIIAKDVYGG-- 104
Cdd:COG0520 38 YYEPYNANVHRGAHELSAEATdaYEAAREKVARFIGAasPDEIIFTRGTteaiNLVAYGLGRLKPGDEILITEMEHHSni 117
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489822298 105 -TFRFVEQvlpRFGITHTFVDTT-----NIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTVAKLAKANGCYTFVD 174
Cdd:COG0520 118 vPWQELAE---RTGAEVRVIPLDedgelDLEALEALLTPRTKLVAVTHVSNVTGTVNPVKEIAALAHAHGALVLVD 190
|
|
| |
