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Conserved domains on  [gi|489820073|ref|WP_003723881|]
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MULTISPECIES: recombination regulator RecX [Listeria]

Protein Classification

regulatory protein RecX( domain architecture ID 10014591)

regulatory protein RecX modulates RecA activities (both recombinase and coprotease) through direct physical interaction

CATH:  1.10.10.10
Gene Ontology:  GO:0006282
PubMed:  18650935

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
3-259 1.22e-115

recombination regulator RecX; Provisional


:

Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 332.56  E-value: 1.22e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073   3 ITSISVQQKNKERYNIFIDEKYNFSVDEEVLARYQLMKGKVLTEADIEEIKQADMVRKGLNKAINFLSHRVRSEKEIRDY 82
Cdd:PRK14135   1 ITKITVQKKNKERYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073  83 LRKQEMEPFAIDEILKKLANMDYINDFEFAELYTKTQIKTTLKGPRTIERELVEKGLTREIISRVIEEYSDEAQLENATK 162
Cdd:PRK14135  81 LKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073 163 QAMKIMKRNNKSAKKMLQQKIITDLIQKGFTSELAKAAATEATSELDVADEAEILQKQIEKTMRKNKRYKPSIAKQKTIT 242
Cdd:PRK14135 161 LAEKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQKLKQ 240
                        250
                 ....*....|....*..
gi 489820073 243 SLMQKGFSYDTIQSYLT 259
Cdd:PRK14135 241 ALYRKGFSYDDIDSFLR 257
 
Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
3-259 1.22e-115

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 332.56  E-value: 1.22e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073   3 ITSISVQQKNKERYNIFIDEKYNFSVDEEVLARYQLMKGKVLTEADIEEIKQADMVRKGLNKAINFLSHRVRSEKEIRDY 82
Cdd:PRK14135   1 ITKITVQKKNKERYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073  83 LRKQEMEPFAIDEILKKLANMDYINDFEFAELYTKTQIKTTLKGPRTIERELVEKGLTREIISRVIEEYSDEAQLENATK 162
Cdd:PRK14135  81 LKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073 163 QAMKIMKRNNKSAKKMLQQKIITDLIQKGFTSELAKAAATEATSELDVADEAEILQKQIEKTMRKNKRYKPSIAKQKTIT 242
Cdd:PRK14135 161 LAEKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQKLKQ 240
                        250
                 ....*....|....*..
gi 489820073 243 SLMQKGFSYDTIQSYLT 259
Cdd:PRK14135 241 ALYRKGFSYDDIDSFLR 257
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
54-207 1.98e-35

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 124.13  E-value: 1.98e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073  54 QADMVRKGLNKAINFLSHRVRSEKEIRDYLRKQEMEPFAIDEILKKLANMDYINDFEFAELYTKTQIKTTLKGPRTIERE 133
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQE 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489820073 134 LVEKGLTREIISRVIEEYSDEAQLENATKQAMKIMKRNNKSAKKMLQQKIITDLIQKGFTSELAKAAATEATSE 207
Cdd:COG2137   81 LRQKGIDEELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELLEE 154
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
83-207 5.61e-28

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 103.82  E-value: 5.61e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073   83 LRKQEMEPFAIDEILKKLANMDYINDFEFAELYTKTQIKTTLKGPRTIERELVEKGLTREIISRVIEEYSDEAQleNATK 162
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQ--IARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 489820073  163 QAMKIMKRNNKSAKKMLQQKIITDLIQKGFTSELAKAAATEATSE 207
Cdd:pfam02631  79 LAEKKFKRYPAESDRKLKQKLIRFLARRGFSSEVIRAALQEEDED 123
 
Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
3-259 1.22e-115

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 332.56  E-value: 1.22e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073   3 ITSISVQQKNKERYNIFIDEKYNFSVDEEVLARYQLMKGKVLTEADIEEIKQADMVRKGLNKAINFLSHRVRSEKEIRDY 82
Cdd:PRK14135   1 ITKITVQKKNKERYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073  83 LRKQEMEPFAIDEILKKLANMDYINDFEFAELYTKTQIKTTLKGPRTIERELVEKGLTREIISRVIEEYSDEAQLENATK 162
Cdd:PRK14135  81 LKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073 163 QAMKIMKRNNKSAKKMLQQKIITDLIQKGFTSELAKAAATEATSELDVADEAEILQKQIEKTMRKNKRYKPSIAKQKTIT 242
Cdd:PRK14135 161 LAEKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQKLKQ 240
                        250
                 ....*....|....*..
gi 489820073 243 SLMQKGFSYDTIQSYLT 259
Cdd:PRK14135 241 ALYRKGFSYDDIDSFLR 257
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
54-207 1.98e-35

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 124.13  E-value: 1.98e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073  54 QADMVRKGLNKAINFLSHRVRSEKEIRDYLRKQEMEPFAIDEILKKLANMDYINDFEFAELYTKTQIKTTLKGPRTIERE 133
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQE 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489820073 134 LVEKGLTREIISRVIEEYSDEAQLENATKQAMKIMKRNNKSAKKMLQQKIITDLIQKGFTSELAKAAATEATSE 207
Cdd:COG2137   81 LRQKGIDEELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELLEE 154
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
83-207 5.61e-28

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 103.82  E-value: 5.61e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073   83 LRKQEMEPFAIDEILKKLANMDYINDFEFAELYTKTQIKTTLKGPRTIERELVEKGLTREIISRVIEEYSDEAQleNATK 162
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQ--IARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 489820073  163 QAMKIMKRNNKSAKKMLQQKIITDLIQKGFTSELAKAAATEATSE 207
Cdd:pfam02631  79 LAEKKFKRYPAESDRKLKQKLIRFLARRGFSSEVIRAALQEEDED 123
recX PRK14134
recombination regulator RecX; Provisional
1-258 5.86e-21

recombination regulator RecX; Provisional


Pssm-ID: 184530 [Multi-domain]  Cd Length: 283  Bit Score: 89.48  E-value: 5.86e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073   1 MKITSISVQQKNKERYNIFIDEKYNFSVDEEVLARYQLMKGKVLTEADIEEIKQADMVRKGLNKAINFLSHRVRSEKEIR 80
Cdd:PRK14134   3 NIITKIEVQKRNKDRVNVYIDEEFAFACSAELVYYHNLKKGKVIDVNSLNDIIKEDNYIKCKGYALKYIEKSYKTEKQIK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073  81 DYLRKQEMEPFAIDEILKKLANMDYINDFEFAELYTKTQIktTLKGPRTIERELVEKGLTREIISRVIEEYSDEAQLENA 160
Cdd:PRK14134  83 EKLYLKEYDEDAVNRVIRFLKEYNFIDDDKYCDMYIREKI--NSYGRNKIKYTLLNKGIKENIIIEKINNIDEEKEKKVA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073 161 TKQAMK---IMKRNNKSAKKMLqQKIITDLIQKGFTSELAKAAATEATSELDVADE--AEILQKQIEKTMRKN------K 229
Cdd:PRK14134 161 YKLAEKkykILILSEKNKFKIY-KKLGPYLISRGYSSNIAEWILNELIKNEALYKDnnSQNIENNIKDENIEElhnlarK 239
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 489820073 230 RYKPSIAKQ--------KTITSLMQKGFSYDTIQSYL 258
Cdd:PRK14134 240 RYDIIIKSEddknkiyrRLSNYLLRRGYSWEEVKKSL 276
recX PRK00117
recombination regulator RecX; Reviewed
50-207 1.65e-18

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 79.93  E-value: 1.65e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820073  50 EEIKQADMVRKGLNKAINFLSHRVRSEKEIRDYLRKQEMEPFAIDEILKKLANMDYINDFEFAELYTKTQIKTTlKGPRT 129
Cdd:PRK00117   2 EDTARRRMYASARARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRARKG-YGPRR 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489820073 130 IERELVEKGLTREIISRVIEEYsDEAQLENATKQAMKIMKRNNKSAKKMLqQKIITDLIQKGFTSELAKAAATEATSE 207
Cdd:PRK00117  81 IRQELRQKGVDREIIEEALAEL-DIDWEELARELARKKFRRPLPDDAKEK-AKLVRFLARRGFSMDVIQRVLRNALDD 156
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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