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Conserved domains on  [gi|489736871|ref|WP_003640966|]
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MULTISPECIES: DNA polymerase III subunit delta' [Lactiplantibacillus]

Protein Classification

DNA polymerase III subunit delta'( domain architecture ID 11483073)

DNA polymerase III subunit delta' interacts with the delta and gamma subunits and is part of the clamp-loading complex, which assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
 5-334 1.14e-169

DNA polymerase III subunit delta'; Validated


:

Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 474.80  E-value: 1.14e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   5 ESFAQTLAAKQPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDI 84
Cdd:PRK08058   1 MMTWEQLTALQPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  85 VTVAPEGQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISR 164
Cdd:PRK08058  81 HLVAPDGQSIKKDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 165 TQVIEFPPLNAQALQQTFEQAGIAPNQAQMLRGLTNSVTQAQALLADDWLPQAAQALWRWFDQAVKGDPRSFVAVQVNLV 244
Cdd:PRK08058 161 CQVVEFRPLPPESLIQRLQEEGISESLATLLAGLTNSVEEALALSEDDWFAQARALVIKLYEALHEKDLQSFVFVQEKWM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 245 GLAKDADHQLVMLDLIAALFQDLLQLHFEVATTALTFGQYQkELAGLTAEVSDEQLIAATELALTAKRQLASNISFQNVL 324
Cdd:PRK08058 241 PLFKEKDQQQLGLDLLLLIYRDLLYLQLGEEDRLVFREQKE-MLQQLALSYSQQQIVAALELILEAKRRLNSNVNFQLVM 319

                        330
                 ....*....|
gi 489736871 325 EGLTLKLWPI 334
Cdd:PRK08058 320 EQLVLRLQEG 329
 
Name Accession Description Interval E-value
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
 5-334 1.14e-169

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 474.80  E-value: 1.14e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   5 ESFAQTLAAKQPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDI 84
Cdd:PRK08058   1 MMTWEQLTALQPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  85 VTVAPEGQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISR 164
Cdd:PRK08058  81 HLVAPDGQSIKKDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 165 TQVIEFPPLNAQALQQTFEQAGIAPNQAQMLRGLTNSVTQAQALLADDWLPQAAQALWRWFDQAVKGDPRSFVAVQVNLV 244
Cdd:PRK08058 161 CQVVEFRPLPPESLIQRLQEEGISESLATLLAGLTNSVEEALALSEDDWFAQARALVIKLYEALHEKDLQSFVFVQEKWM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 245 GLAKDADHQLVMLDLIAALFQDLLQLHFEVATTALTFGQYQkELAGLTAEVSDEQLIAATELALTAKRQLASNISFQNVL 324
Cdd:PRK08058 241 PLFKEKDQQQLGLDLLLLIYRDLLYLQLGEEDRLVFREQKE-MLQQLALSYSQQQIVAALELILEAKRRLNSNVNFQLVM 319

                        330
                 ....*....|
gi 489736871 325 EGLTLKLWPI 334
Cdd:PRK08058 320 EQLVLRLQEG 329
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 14-174 3.74e-85

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 254.06  E-value: 3.74e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   14 KQPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPEGQR 93
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   94 IHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPL 173
Cdd:pfam13177  81 IKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160


                  .
gi 489736871  174 N 174
Cdd:pfam13177 161 S 161
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
15-331 1.24e-84

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 258.97  E-value: 1.24e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPEGQRI 94
Cdd:COG2812   15 QEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVIEIDAEASNI 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  95 HVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPLN 174
Cdd:COG2812   95 GVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFRRLP 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 175 ----AQALQQTFEQAGIA--PNQAQMLRGLTN-SVTQAQALLADDW---LPQAAQALWRWFDQAVKGDPRSFVAVQVNLV 244
Cdd:COG2812  175 peeiAEHLAKIAEREGIEiePEALALIARAADgSMRDALSLLDQAIafgLLDRRELLLDLLEALLAGDVAALLALAEELA 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 245 GLAKDadhQLVMLDLIAALFQDLLQLHFEVATTALTFGQYQKELAGLTAEVSDEQLIAATELALTAKRQLASNISFQNVL 324
Cdd:COG2812  255 KRGRD---LKRFLDDLLSLLRDLLLLKLGPDAELLVNEDERERLQELARRLSPERLLRAIQILLEARRELERNVNPRLAL 331


                 ....*..
gi 489736871 325 EGLTLKL 331
Cdd:COG2812  332 EMLLLRL 338
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 19-205 1.78e-78

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 237.91  E-value: 1.78e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   19 LAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPEGQRIHVDQ 98
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSIKVDQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   99 VRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPLNAQAL 178
Cdd:TIGR00678  81 VRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEAL 160

                         170       180
                  ....*....|....*....|....*..
gi 489736871  179 QQTFEQAGIAPNQAQMLRGLTNSVTQA 205
Cdd:TIGR00678 161 LQWLIRQGISEEAAELLLALAGGSPGR 187
 
Name Accession Description Interval E-value
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
 5-334 1.14e-169

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 474.80  E-value: 1.14e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   5 ESFAQTLAAKQPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDI 84
Cdd:PRK08058   1 MMTWEQLTALQPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  85 VTVAPEGQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISR 164
Cdd:PRK08058  81 HLVAPDGQSIKKDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 165 TQVIEFPPLNAQALQQTFEQAGIAPNQAQMLRGLTNSVTQAQALLADDWLPQAAQALWRWFDQAVKGDPRSFVAVQVNLV 244
Cdd:PRK08058 161 CQVVEFRPLPPESLIQRLQEEGISESLATLLAGLTNSVEEALALSEDDWFAQARALVIKLYEALHEKDLQSFVFVQEKWM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 245 GLAKDADHQLVMLDLIAALFQDLLQLHFEVATTALTFGQYQkELAGLTAEVSDEQLIAATELALTAKRQLASNISFQNVL 324
Cdd:PRK08058 241 PLFKEKDQQQLGLDLLLLIYRDLLYLQLGEEDRLVFREQKE-MLQQLALSYSQQQIVAALELILEAKRRLNSNVNFQLVM 319

                        330
                 ....*....|
gi 489736871 325 EGLTLKLWPI 334
Cdd:PRK08058 320 EQLVLRLQEG 329
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 14-174 3.74e-85

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 254.06  E-value: 3.74e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   14 KQPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPEGQR 93
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   94 IHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPL 173
Cdd:pfam13177  81 IKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160


                  .
gi 489736871  174 N 174
Cdd:pfam13177 161 S 161
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
15-331 1.24e-84

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 258.97  E-value: 1.24e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPEGQRI 94
Cdd:COG2812   15 QEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVIEIDAEASNI 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  95 HVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPLN 174
Cdd:COG2812   95 GVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFRRLP 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 175 ----AQALQQTFEQAGIA--PNQAQMLRGLTN-SVTQAQALLADDW---LPQAAQALWRWFDQAVKGDPRSFVAVQVNLV 244
Cdd:COG2812  175 peeiAEHLAKIAEREGIEiePEALALIARAADgSMRDALSLLDQAIafgLLDRRELLLDLLEALLAGDVAALLALAEELA 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 245 GLAKDadhQLVMLDLIAALFQDLLQLHFEVATTALTFGQYQKELAGLTAEVSDEQLIAATELALTAKRQLASNISFQNVL 324
Cdd:COG2812  255 KRGRD---LKRFLDDLLSLLRDLLLLKLGPDAELLVNEDERERLQELARRLSPERLLRAIQILLEARRELERNVNPRLAL 331


                 ....*..
gi 489736871 325 EGLTLKL 331
Cdd:COG2812  332 EMLLLRL 338
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 19-205 1.78e-78

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 237.91  E-value: 1.78e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   19 LAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPEGQRIHVDQ 98
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSIKVDQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   99 VRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPLNAQAL 178
Cdd:TIGR00678  81 VRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEAL 160

                         170       180
                  ....*....|....*....|....*..
gi 489736871  179 QQTFEQAGIAPNQAQMLRGLTNSVTQA 205
Cdd:TIGR00678 161 LQWLIRQGISEEAAELLLALAGGSPGR 187
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
 10-329 6.69e-67

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 212.18  E-value: 6.69e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  10 TLAAKQPRLLAAFKHIIAQNHLAHAYLFAGmeGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAP 89
Cdd:PRK07276   2 DLKQKQPKVFQRFQTILEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVIEP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  90 EGQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIE 169
Cdd:PRK07276  80 QGQVIKTDTIRELVKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFH 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 170 FPPlNAQALQQTFEQAGIAPNQAQMLRGLTNSVTQAQALLADDWLPQAAQALWRWFDQAVKGDPRSFVAVQvNLVGLAKD 249
Cdd:PRK07276 160 FPK-NEAYLIQLLEQKGLLKTQAELLAKLAQSTSEAEKLAQNKKFLELIDQAERFVTILLKDKDEAYLQVA-RLVQLADE 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 250 ADHQlvmlDLIaalFQDLLQLhfevattaltfgqyqkelagLTAEVSDEQLIAATELALTAKRQLASNISFQNVLEGLTL 329
Cdd:PRK07276 238 KEEQ----DQV---LTLLTLL--------------------LAQERMQVNVRTQLEAVYQARKMWQSNVSFQNALEYMVL 290
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
15-331 1.20e-55

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 182.87  E-value: 1.20e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEeCVRIANGSHPDIVTVAPE--GQ 92
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELNPEekSD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  93 RIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPP 172
Cdd:COG0470   80 QIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 173 LNAQALQQTFEQAGIAPNQAQM-LRGLTNSVTQAQALLADDwlpQAAQALWRWFDQAVKGDPRSFVAVQVNlvglakdAD 251
Cdd:COG0470  160 PSEEEALAWLREEGVDEDALEAiLRLAGGDPRAAINLLQAL---AGRKELLEDLAALLSRDRALELLDALL-------KA 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 252 HQLVMLDLIAALFQDLLQLHFevattaltfgqyqkelagltaevSDEQLIAATELALTAKRQLASNISFQNVLEGLTLKL 331
Cdd:COG0470  230 EALELLDWLLKWLLDNLPLEY-----------------------AGEDLARAYEALSEADRRLGRYANDRLLLEALLAKL 286
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
 20-331 2.20e-36

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 133.67  E-value: 2.20e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  20 AAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPE--GQRIHVD 97
Cdd:PRK05707  10 SLWQQLAGRGRHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNFVLEPEeaDKTIKVD 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  98 QVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPLNAQA 177
Cdd:PRK05707  90 QVRELVSFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEE 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 178 LQQTFEQA---GIAPNQAQMLRGLTNSVTQAQALLADDWLPQAAQALwrwfdQAVKgdprSFVAVQVNLVGLAKD--ADH 252
Cdd:PRK05707 170 SLQWLQQAlpeSDERERIELLTLAGGSPLRALQLHEQGVREQRARVL-----DGVK----KLLKQQQSASQLAESwlKVP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 253 QLVMLDLIAALFQDLLQLHFEVATTALTFGQYQKELAGLTAEVSDEQLIAATELALTAKRQLAS--NISFQNVLEGLTLK 330
Cdd:PRK05707 241 LLLLFDWFCDWAHDILRYQLTQDEEGLGLADMRKVLQYLAQKSPQAKVLALQDWLLEQRQKVLGkaNLNRQLLLEALLVQ 320


                 .
gi 489736871 331 L 331
Cdd:PRK05707 321 W 321
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
 15-187 6.60e-33

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 124.24  E-value: 6.60e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFClhinDGEPDGTCEEcvRIANGSHPDIVTVAP----E 90
Cdd:PRK07399   9 QPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGLLS----QGSPSKNIRR--RLEEGNHPDLLWVEPtyqhQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  91 GQR------------------IHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPsGNVTALLLTT 152
Cdd:PRK07399  83 GKLitaseaeeaglkrkappqIRLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEEP-GNGTLILIAP 161

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 489736871 153 NKQLMLPTIISRTQVIEFPPLNAQALQQTFEQAGI 187
Cdd:PRK07399 162 SPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGD 196
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
 16-225 4.61e-30

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 116.76  E-value: 4.61e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  16 PRLLAAFKHIIA---QNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAP-EG 91
Cdd:PRK06871   5 PWLQPTYQQITQafqQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILEPiDN 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  92 QRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQV-IEF 170
Cdd:PRK06871  85 KDIGVDQVREINEKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQTwLIH 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 489736871 171 PPLNAQALQQTFEQAGIAPNQAQM-LRGLTNSVTQAQALLADDWLPQAA---QALWRWF 225
Cdd:PRK06871 165 PPEEQQALDWLQAQSSAEISEILTaLRINYGRPLLALTFLEQGLLEQRKtflRQFWLFY 223
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
 21-170 5.72e-30

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 119.10  E-value: 5.72e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  21 AFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPEGQRiHVDQVR 100
Cdd:PRK14962  25 LIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSIDEGTFMDVIELDAASNR-GIDEIR 103

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 101 YLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEF 170
Cdd:PRK14962 104 KIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTIISRCQVIEF 173
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
 22-229 1.90e-28

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 114.92  E-value: 1.90e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  22 FKHIIAQNH-------------LAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVA 88
Cdd:PRK14953  15 FKEVIGQEIvvrilknavklqrVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCVEIDKGSFPDLIEID 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  89 PEGQRiHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVI 168
Cdd:PRK14953  95 AASNR-GIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTILSRCQRF 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489736871 169 EFPPLNA----QALQQTFEQAGIaPNQAQMLRGLtnsvtqaqALLADDWLPQAAQALwrwfDQAV 229
Cdd:PRK14953 174 IFSKPTKeqikEYLKRICNEEKI-EYEEKALDLL--------AQASEGGMRDAASLL----DQAS 225
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 9-179 1.53e-27

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 113.24  E-value: 1.53e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   9 QTLA--AKQPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVT 86
Cdd:PRK14959  13 QTFAevAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCRKVTQGMHVDVVE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  87 VAPEGQRiHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQ 166
Cdd:PRK14959  93 IDGASNR-GIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPVTIVSRCQ 171

                        170
                 ....*....|...
gi 489736871 167 VIEFPPLNAQALQ 179
Cdd:PRK14959 172 HFTFTRLSEAGLE 184
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
 18-186 4.16e-26

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 108.39  E-value: 4.16e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  18 LLAAfkhiIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHiNDGEPDGTCEECVRIANGSHPDIVTVAPEGQRiHVD 97
Cdd:PRK14963  26 LLAA----LRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNCSG-EDPKPCGECESCLAVRRGAHPDVLEIDAASNN-SVE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  98 QVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPLN--- 174
Cdd:PRK14963 100 DVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTILSRTQHFRFRRLTeee 179

                        170
                 ....*....|...
gi 489736871 175 -AQALQQTFEQAG 186
Cdd:PRK14963 180 iAGKLRRLLEAEG 192
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
 34-275 9.39e-26

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 104.89  E-value: 9.39e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  34 AYLFAGMEGAGQPELAHWIAQRLFCLHINDgEPDGTCEECVRIANGSHPDIVTVAPE--GQRIHVDQVRYLKAEFSKSAV 111
Cdd:PRK06090  27 ALLLQSDEGLGVESLVELFSRALLCQNYQS-EACGFCHSCELMQSGNHPDLHVIKPEkeGKSITVEQIRQCNRLAQESSQ 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 112 EGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQ--VIEfPPLNAQALQQTFEQAGIAP 189
Cdd:PRK06090 106 LNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQqwVVT-PPSTAQAMQWLKGQGITVP 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 190 nqAQMLRGLTNSVTQAQALLADDWLpQAAQALWRWFDQAVKGDprsfVAVQVNLVGL-AKDADHQlvmLDLIAALFQDLL 268
Cdd:PRK06090 185 --AYALKLNMGSPLKTLAMMKEGGL-EKYHKLERQLVDALSGP----VSDQLKCASLiAADPLTH---LSWLWLLLTDAQ 254


                 ....*..
gi 489736871 269 QLHFEVA 275
Cdd:PRK06090 255 KVHFGVQ 261
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
 22-174 8.76e-24

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 99.34  E-value: 8.76e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  22 FKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDgepdgtceecvriangSHPDIVTVAPEGQR-IHVDQVR 100
Cdd:PRK05564  16 IKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIALKILGKSQQR----------------EYVDIIEFKPINKKsIGVDDIR 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489736871 101 YLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPLN 174
Cdd:PRK05564  80 NIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLS 153
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
15-170 2.39e-22

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 97.92  E-value: 2.39e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHIN-DGEPDGTCEECVRI--------------ANG 79
Cdd:PRK14971  22 QEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQNLTaDGEACNECESCVAFneqrsyniheldaaSNN 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  80 SHPDIvtvapegqRIHVDQVRYlkaefskSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLP 159
Cdd:PRK14971 102 SVDDI--------RNLIEQVRI-------PPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILP 166

                        170
                 ....*....|.
gi 489736871 160 TIISRTQVIEF 170
Cdd:PRK14971 167 TILSRCQIFDF 177
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 9-170 6.42e-22

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 96.42  E-value: 6.42e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   9 QTLA--AKQPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHiND--GEPDGTCEECVRIANGSHPDI 84
Cdd:PRK14950  13 QTFAelVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTT-NDpkGRPCGTCEMCRAIAEGSAVDV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  85 VTVaPEGQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISR 164
Cdd:PRK14950  92 IEM-DAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPATILSR 170


                 ....*.
gi 489736871 165 TQVIEF 170
Cdd:PRK14950 171 CQRFDF 176
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
 31-193 1.20e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 94.59  E-value: 1.20e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  31 LAHAYLFAGMEGAGQPELAHWIAQRLFClhINDGEPD-GTCEECVRIANGSHPDIVTVAPEGQRIHVDQVRYLKAEFSKS 109
Cdd:PRK07940  35 MTHAWLFTGPPGSGRSVAARAFAAALQC--TDPDEPGcGECRACRTVLAGTHPDVRVVAPEGLSIGVDEVRELVTIAARR 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 110 AVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFP-PLNAQALQQTFEQAGIA 188
Cdd:PRK07940 113 PSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRCRHVALRtPSVEAVAEVLVRRDGVD 192


                 ....*
gi 489736871 189 PNQAQ 193
Cdd:PRK07940 193 PETAR 197
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
 18-214 1.45e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 93.94  E-value: 1.45e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  18 LLAAFkhiiAQNHLAHAYLFAGMEGAGQPELAHWIAQrlFCLHINDGEPDGTCEE------------CVRIANGSHPDIV 85
Cdd:PRK07471  31 LLDAY----RSGRLHHAWLIGGPQGIGKATLAYRMAR--FLLATPPPGGDGAVPPptslaidpdhpvARRIAAGAHGGLL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  86 TV----APEGQR----IHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLM 157
Cdd:PRK07471 105 TLerswNEKGKRlrtvITVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARL 184

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 158 LPTIISRTQVIEFPPLNAQALQQTFEQAG--IAPNQAQMLRGLTN-SVTQAQALLADDWL 214
Cdd:PRK07471 185 LPTIRSRCRKLRLRPLAPEDVIDALAAAGpdLPDDPRAALAALAEgSVGRALRLAGGDGL 244
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
 34-194 3.21e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 92.63  E-value: 3.21e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  34 AYLFAGMEGAGQPELAHWIAQRLFCLH-INDGEPDGTCEECVRIANGSHPDIVTVAPEGQ---------RIHVDQVRYLK 103
Cdd:PRK08699  23 AWLFAGKKGIGKTAFARFAAQALLCETpAPGHKPCGECMSCHLFGQGSHPDFYEITPLSDepengrkllQIKIDAVREII 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 104 AEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPLNAQALQQTFE 183
Cdd:PRK08699 103 DNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAPSHEEALAYLR 182

                        170
                 ....*....|.
gi 489736871 184 QAGIAPNQAQM 194
Cdd:PRK08699 183 ERGVAEPEERL 193
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
 22-180 6.66e-21

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 93.37  E-value: 6.66e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  22 FKHIIAQNH-------------LAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVA 88
Cdd:PRK05896  15 FKQIIGQELikkilvnailnnkLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCESINTNQSVDIVELD 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  89 PEGQ------RIHVDQVRYLKAEFSKsavegnrKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTII 162
Cdd:PRK05896  95 AASNngvdeiRNIIDNINYLPTTFKY-------KVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKIPLTII 167

                        170
                 ....*....|....*...
gi 489736871 163 SRTQVIEFPPLNAQALQQ 180
Cdd:PRK05896 168 SRCQRYNFKKLNNSELQE 185
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
 15-170 4.96e-20

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 91.03  E-value: 4.96e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHIND-GEPdgtCEECVRIANGSHpDIVTV---APE 90
Cdd:PRK07133  23 QDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSHKTDlLEP---CQECIENVNNSL-DIIEMdaaSNN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  91 GqrihVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEF 170
Cdd:PRK07133  99 G----VDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKIPLTILSRVQRFNF 174
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
 23-170 6.46e-20

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 90.31  E-value: 6.46e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  23 KHI-------IAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVtvapE----- 90
Cdd:PRK05563  22 EHItktlknaIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICKAITNGSLMDVI----Eidaas 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  91 --GqrihVDQVRYL--KAEFSKSavEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQ 166
Cdd:PRK05563  98 nnG----VDEIRDIrdKVKYAPS--EAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPHKIPATILSRCQ 171


                 ....
gi 489736871 167 VIEF 170
Cdd:PRK05563 172 RFDF 175
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
 5-170 6.56e-20

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 90.48  E-value: 6.56e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   5 ESFAQTLaakqprllaafKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDI 84
Cdd:PRK08451  20 ESVSKTL-----------SLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSALENRHIDI 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  85 VTVAPEGQRiHVDQVRYLkAEFSKSAVEGNR-KLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKqLMLP-TII 162
Cdd:PRK08451  89 IEMDAASNR-GIDDIREL-IEQTKYKPSMARfKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDP-LKLPaTIL 165


                 ....*...
gi 489736871 163 SRTQVIEF 170
Cdd:PRK08451 166 SRTQHFRF 173
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
 5-166 8.59e-20

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 89.83  E-value: 8.59e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   5 ESFAQTLAakQPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHI-NDGEPDGTCEECVRIANGSHPD 83
Cdd:PRK06305  14 QTFSEILG--QDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNPtEDQEPCNQCASCKEISSGTSLD 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  84 IVTVAPEGQRiHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIIS 163
Cdd:PRK06305  92 VLEIDGASHR-GIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIPGTILS 170


                 ...
gi 489736871 164 RTQ 166
Cdd:PRK06305 171 RCQ 173
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
 19-184 1.70e-19

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 88.85  E-value: 1.70e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  19 LAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPEGQRiHVDQ 98
Cdd:PRK14956  27 IGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLEITKGISSDVLEIDAASNR-GIEN 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  99 VRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPLNAQAL 178
Cdd:PRK14956 106 IRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPETILSRCQDFIFKKVPLSVL 185


                 ....*.
gi 489736871 179 QQTFEQ 184
Cdd:PRK14956 186 QDYSEK 191
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 15-209 2.88e-19

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 88.61  E-value: 2.88e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVaPEGQRI 94
Cdd:PRK08691  21 QEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQIDAGRYVDLLEI-DAASNT 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  95 HVDQVRYL--KAEFSKSAveGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPP 172
Cdd:PRK08691 100 GIDNIREVleNAQYAPTA--GKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVTVLSRCLQFVLRN 177

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 489736871 173 LNAQA----LQQTFEQAGIA--PNQAQML-RGLTNSVTQAQALL 209
Cdd:PRK08691 178 MTAQQvadhLAHVLDSEKIAyePPALQLLgRAAAGSMRDALSLL 221
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
 24-210 2.99e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 87.40  E-value: 2.99e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  24 HIIAQNH----LAHAYLFAGMEGAGQPELAHWIAQRLFC--------LHINDGEPDGTCEEcvRIANGSHPDIVTVA-PE 90
Cdd:PRK09112  33 AFLAQAYregkLHHALLFEGPEGIGKATLAFHLANHILShpdpaeapETLADPDPASPVWR--QIAQGAHPNLLHITrPF 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  91 GQR-------IHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIIS 163
Cdd:PRK09112 111 DEKtgkfktaITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRS 190

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489736871 164 RTQVIEFPPLNAQALQQTFEQAGIAPNQAQMLRGL-----TNSVTQAQALLA 210
Cdd:PRK09112 191 RCQPISLKPLDDDELKKALSHLGSSQGSDGEITEAllqrsKGSVRKALLLLN 242
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
 9-301 9.39e-19

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 87.11  E-value: 9.39e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   9 QTLAAK-QPRLLA----------AFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIA 77
Cdd:PRK14969   4 QVLARKwRPKSFSelvgqehvvrALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACLEID 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  78 NGSHPDIVTVAPEGQRiHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLM 157
Cdd:PRK14969  84 SGRFVDLIEVDAASNT-QVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKI 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 158 LPTIISRtqVIEF------PPLNAQALQQTFEQAGIAPNQAqmlrgltnsvtqAQALLAddwlpQAAQALWR----WFDQ 227
Cdd:PRK14969 163 PVTVLSR--CLQFnlkqmpPPLIVSHLQHILEQENIPFDAT------------ALQLLA-----RAAAGSMRdalsLLDQ 223

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489736871 228 AVKGDPRSFVAVQVNLVGLAKDADHQLVMLDLIAAlfQD---LLQLHFEVATTALTFGQYQKELAGLTAEVSDEQLI 301
Cdd:PRK14969 224 AIAYGGGTVNESEVRAMLGAIDQDYLFALLEALLA--QDgaaLLAIADAMEERSLSFDAALQDLAALLHRLAIAQTV 298
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
 30-251 1.50e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 85.20  E-value: 1.50e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  30 HLAHAYLFAGMEGAGQPELAHWIAQRLFCLHIN-DGEPDGTCEECVRIANGSHPDIVTVAPE------------------ 90
Cdd:PRK06964  19 RLPHALLLHGQAGIGKLDFAQHLAQGLLCETPQpDGEPCGTCAACNWFAQGNHPDYRIVRPEalaaeapgaadeakeada 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  91 ----------GQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPT 160
Cdd:PRK06964  99 deggkktkapSKEIKIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLLPT 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 161 IISRTQVIEFPPLNAQALQQTFEQAGIAPNQAQM-------LRGLTNSVTQAQALLaDDWLPQAAQA------------- 220
Cdd:PRK06964 179 ILSRCRQFPMTVPAPEAAAAWLAAQGVADADALLaeaggapLAALALASDENRPLR-DWTLGQLAAGaacdafacaetlq 257

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 489736871 221 ----------LWRW-FD---QAVKGDPRSFVAVQVNLVGLAKDAD 251
Cdd:PRK06964 258 klpvpavlgwLQRWlYDllaQRLAGAPRYFPAQRAALARCAAAVD 302
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
 15-185 8.91e-18

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 84.05  E-value: 8.91e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVapEG-QR 93
Cdd:PRK06647  21 QDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCKSIDNDNSLDVIEI--DGaSN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  94 IHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPL 173
Cdd:PRK06647  99 TSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKSRCQHFNFRLL 178

                        170
                 ....*....|..
gi 489736871 174 NAQALQQTFEQA 185
Cdd:PRK06647 179 SLEKIYNMLKKV 190
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
 15-166 2.82e-17

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 82.60  E-value: 2.82e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLH-INDGEPDGTCEEC---VRIANGSHPDIVTVaPE 90
Cdd:PRK06645  26 QEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSAlITENTTIKTCEQCtncISFNNHNHPDIIEI-DA 104

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489736871  91 GQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQ 166
Cdd:PRK06645 105 ASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTEVQKIPATIISRCQ 180
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
 15-209 1.26e-16

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 80.54  E-value: 1.26e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVaPEGQRI 94
Cdd:PRK14958  21 QAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCREIDEGRFPDLFEV-DAASRT 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  95 HVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRT---QVIEFP 171
Cdd:PRK14958 100 KVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTVLSRClqfHLAQLP 179

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 489736871 172 PLNAQA-LQQTFEQAGIAPNQAQ---MLRGLTNSVTQAQALL 209
Cdd:PRK14958 180 PLQIAAhCQHLLKEENVEFENAAldlLARAANGSVRDALSLL 221
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
 69-164 1.66e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 77.95  E-value: 1.66e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  69 TCEECVRIANGSHPDIVTVAPEGQRIHVDQVRYLKAEFSKSAVEGN-RKLFIINDAEKMTASAANSLLKFIEEPSGNVTA 147
Cdd:PRK05818  42 TCESCLKILNGKYNDFYLIFDQKNPIKKEDALSIINKLNRPSVESNgKKIYIIYGIEKLNKQSANSLLKLIEEPPKNTYG 121

                         90
                 ....*....|....*..
gi 489736871 148 LLLTTNKQLMLPTIISR 164
Cdd:PRK05818 122 IFTTRNENNILNTILSR 138
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
 5-331 4.59e-16

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 78.97  E-value: 4.59e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   5 ESFAQTlaAKQPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDI 84
Cdd:PRK14957  13 QSFAEV--AGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCVAINNNSFIDL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  85 VTVaPEGQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISR 164
Cdd:PRK14957  91 IEI-DAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVTILSR 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 165 TQVIEFPPL----------------NAQALQQTFEQagIAPNQAQMLRGLTNSVTQAQALLADDwLPQA----------A 218
Cdd:PRK14957 170 CIQLHLKHIsqadikdqlkiilakeNINSDEQSLEY--IAYHAKGSLRDALSLLDQAISFCGGE-LKQAqikqmlgiidS 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 219 QALWRWFDQAVKGDPRSFVAVQVNLVGLAKDADhqlVMLDLIAALFQDLLQLHFEVATTALTFGQYQKeLAGLTAEVSDE 298
Cdd:PRK14957 247 EEVYSIINAIIDNDPKAILPAIKNLALTESSAD---AVLDRIAEIWFACCIYSFTQSLDAVNDIDVDI-INNILAKISIE 322

                        330       340       350
                 ....*....|....*....|....*....|...
gi 489736871 299 QLIAATELALTAKRQLASNISFQNVLEGLTLKL 331
Cdd:PRK14957 323 QAHFLYQLTITAKKDIALAPNFETGVTMAILRL 355
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
20-179 5.24e-16

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 78.77  E-value: 5.24e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  20 AAFKHIIAQNH-------------LAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIA-NG-SHPDI 84
Cdd:PRK14952  10 ATFAEVVGQEHvteplssaldagrINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVALApNGpGSIDV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  85 VTV--APEGQrihVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTII 162
Cdd:PRK14952  90 VELdaASHGG---VDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIR 166

                        170
                 ....*....|....*..
gi 489736871 163 SRTQVIEFPPLNAQALQ 179
Cdd:PRK14952 167 SRTHHYPFRLLPPRTMR 183
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
 15-191 6.46e-16

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 77.61  E-value: 6.46e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGT--CEECVRIANGSHPDIvtvapegq 92
Cdd:PRK14970  22 QSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDDPNEDFSfnIFELDAASNNSVDDI-------- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  93 RIHVDQVRYlkaefskSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPP 172
Cdd:PRK14970  94 RNLIDQVRI-------PPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDFKR 166

                        170
                 ....*....|....*....
gi 489736871 173 LNAQALQQTFeqAGIAPNQ 191
Cdd:PRK14970 167 ITIKDIKEHL--AGIAVKE 183
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
5-187 4.07e-15

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 76.15  E-value: 4.07e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   5 ESFAQTLaakqprllaafKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHiNDG---EPDGTCEECVRIANGSH 81
Cdd:PRK14948  22 EAIATTL-----------KNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNCLN-SDKptpEPCGKCELCRAIAAGNA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  82 PDIVtvapegqRIH------VDQVRYL--KAEFSksAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTN 153
Cdd:PRK14948  90 LDVI-------EIDaasntgVDNIRELieRAQFA--PVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTD 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 489736871 154 KQLMLPTIISRTQVIEFP--PLNA--QALQQTFEQAGI 187
Cdd:PRK14948 161 PQRVLPTIISRCQRFDFRriPLEAmvQHLSEIAEKESI 198
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
 29-170 4.57e-15

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 75.98  E-value: 4.57e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  29 NHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVaPEGQRIHVDQVRYLKAEFSK 108
Cdd:PRK14964  32 NKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKNSNHPDVIEI-DAASNTSVDDIKVILENSCY 110

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489736871 109 SAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEF 170
Cdd:PRK14964 111 LPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVTIISRCQRFDL 172
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
 75-332 9.77e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 73.29  E-value: 9.77e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  75 RIANGSHPDIVTVAPEGQ-RIH-VDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTT 152
Cdd:PRK05917  54 KISQKIHPDIHEFSPQGKgRLHsIETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSA 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 153 NKQLMLPTIISRTQVIEFPplnaqalqqtfEQAGIAPNQAQM--LRGLTN---SVTQAqalladdwlpqaaqalwrwfDQ 227
Cdd:PRK05917 134 KPQRLPPTIRSRSLSIHIP-----------MEEKTLVSKEDIayLIGYAQgkeSVTEV--------------------GQ 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 228 AVKGDPrsfvavqvnlvglakDADHQL------VMLDLIAALFQDLLQLHFEVATTALTFGQYQKELAGLTAEVSDEQLI 301
Cdd:PRK05917 183 IVKGSA---------------DTDKQVlrdktkAMLEVLLQLFRDRFLLALKVPASALAYPDLLKEILTLPVLPLEKVLS 247

                        250       260       270
                 ....*....|....*....|....*....|.
gi 489736871 302 AATElaltAKRQLASNISFQNVLEGLTLKLW 332
Cdd:PRK05917 248 IIER----AVQALDNSSSAPSCLEWVALQLW 274
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
 108-178 1.27e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 73.22  E-value: 1.27e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489736871 108 KSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFPPLNAQAL 178
Cdd:PRK07132  84 SSFVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKI 154
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
9-173 2.75e-14

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 73.93  E-value: 2.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   9 QTLAAK-QPRllaAFKHIIAQNH-------------LAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECV 74
Cdd:PRK14960   3 QVLARKyRPR---NFNELVGQNHvsralssalergrLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  75 RIANGSHPDIVTVaPEGQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNK 154
Cdd:PRK14960  80 AVNEGRFIDLIEI-DAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDP 158

                        170
                 ....*....|....*....
gi 489736871 155 QLMLPTIISRTQVIEFPPL 173
Cdd:PRK14960 159 QKLPITVISRCLQFTLRPL 177
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 31-192 3.38e-14

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 73.24  E-value: 3.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  31 LAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTV------APEGQRIHVDQVRYLKa 104
Cdd:PRK14965  37 VAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCVEITEGRSVDVFEIdgasntGVDDIRELRENVKYLP- 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 105 efSKSavegNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEFP----PLNAQALQQ 180
Cdd:PRK14965 116 --SRS----RYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKVPITILSRCQRFDFRriplQKIVDRLRY 189

                        170
                 ....*....|..
gi 489736871 181 TFEQAGIAPNQA 192
Cdd:PRK14965 190 IADQEGISISDA 201
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
 20-209 1.40e-13

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 71.08  E-value: 1.40e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  20 AAFKHIIAQNH-------------LAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDG--------EPDGTCEECVRIAN 78
Cdd:PRK14955  13 KKFADITAQEHitrtiqnslrmgrVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDadylqevtEPCGECESCRDFDA 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  79 GSHPDIVTVAPEGQRiHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLML 158
Cdd:PRK14955  93 GTSLNISEFDAASNN-SVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIP 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489736871 159 PTIISRTQVIEFP--PLNA--QALQQTFEQAGIA--PNQAQML-RGLTNSVTQAQALL 209
Cdd:PRK14955 172 ATIASRCQRFNFKriPLEEiqQQLQGICEAEGISvdADALQLIgRKAQGSMRDAQSIL 229
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
15-303 1.81e-13

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 71.06  E-value: 1.81e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHiNDG------EPDGTCEECVRIANGSHPDIVTVA 88
Cdd:PRK12323  21 QEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCTG-ADGeggitaQPCGQCRACTEIDAGRFVDYIEMD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  89 PEGQRiHVDQVRYL--KAEFSKSAveGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRtq 166
Cdd:PRK12323 100 AASNR-GVDEMAQLldKAVYAPTA--GRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSR-- 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 167 VIEF------PPLNAQALQQTFEQAGIApNQAQMLRgltnsvtqaqaLLAddwlpQAAQALWR----WFDQAVkgdprSF 236
Cdd:PRK12323 175 CLQFnlkqmpPGHIVSHLDAILGEEGIA-HEVNALR-----------LLA-----QAAQGSMRdalsLTDQAI-----AY 232

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489736871 237 VAVQVN------LVGlAKDADHQLVMLDLIAAlfQD---LLQLHFEVATTALTFGQYQKELAGLTAEVSDEQLIAA 303
Cdd:PRK12323 233 SAGNVSeeavrgMLG-AIDQSYLVRLLDALAA--EDgaaLLAIADEMAGRSLSFAGALQDLASLLQKIALAQVVPA 305
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
 22-174 1.24e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 67.91  E-value: 1.24e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  22 FKHIIAQNHLA-------------HAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVa 88
Cdd:PRK14961  15 FRDIIGQKHIVtaisnglslgrihHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICKEIEKGLCLDLIEI- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  89 PEGQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVI 168
Cdd:PRK14961  94 DAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKTILSRCLQF 173


                 ....*.
gi 489736871 169 EFPPLN 174
Cdd:PRK14961 174 KLKIIS 179
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
 16-232 1.79e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 67.40  E-value: 1.79e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  16 PRLLAAFKHIIAQnHLA----HAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPEG 91
Cdd:PRK07993   5 PWLRPDYEQLVGS-YQAgrghHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLTPEK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  92 --QRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIE 169
Cdd:PRK07993  84 gkSSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCRLHY 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489736871 170 F-PPLNAQALQQTFEQAGIAPNQAQM-LRGLTNSVTQAQALL-ADDWlpQAAQALWRWFDQAV-KGD 232
Cdd:PRK07993 164 LaPPPEQYALTWLSREVTMSQDALLAaLRLSAGAPGAALALLqPERW--QQREALCQALAYALpSGD 228
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 15-164 2.39e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 67.82  E-value: 2.39e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHInDG------EPDGTCEECVRIANGSHPDIVTVA 88
Cdd:PRK14951  21 QEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCQGP-DGqggitaTPCGVCQACRDIDSGRFVDYTELD 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489736871  89 PEGQRiHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISR 164
Cdd:PRK14951 100 AASNR-GVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQKVPVTVLSR 174
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 15-164 2.54e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 67.83  E-value: 2.54e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVaPEGQRI 94
Cdd:PRK14949  21 QSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCVEIAQGRFVDLIEV-DAASRT 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  95 HVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISR 164
Cdd:PRK14949 100 KVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLPVTVLSR 169
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 20-209 3.67e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 67.28  E-value: 3.67e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  20 AAFKHIIAQNHL-------------AHAYLFAGMEGAGQPELAHWIAQRLFCLHINDG--------EPDGTCEECVRIAN 78
Cdd:PRK14954  13 SKFADITAQEHIthtiqnslrmdrvGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDpvylqevtEPCGECESCRDFDA 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  79 GSHPDIVTVAPEGQRiHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLML 158
Cdd:PRK14954  93 GTSLNISEFDAASNN-SVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTELHKIP 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489736871 159 PTIISRTQVIEFP--PLNA--QALQQTFEQAGIAPNQAQML---RGLTNSVTQAQALL 209
Cdd:PRK14954 172 ATIASRCQRFNFKriPLDEiqSQLQMICRAEGIQIDADALQliaRKAQGSMRDAQSIL 229
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
15-164 5.09e-11

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 63.72  E-value: 5.09e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANGSHPDIVTVAPEGQRi 94
Cdd:PRK07003  21 QEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNR- 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  95 HVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISR 164
Cdd:PRK07003 100 GVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSR 169
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
 6-248 2.45e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 60.74  E-value: 2.45e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871   6 SFAQTLAAkqprllaafkhiIAQNHLAHAYLFAGMEGAGQPELAHWIAQrlfclHINDGEPDGTCEECVR--IANGSHPD 83
Cdd:PRK08769  12 AYDQTVAA------------LDAGRLGHGLLICGPEGLGKRAVALALAE-----HVLASGPDPAAAQRTRqlIAAGTHPD 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  84 IVTVAPEGQR--------IHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQ 155
Cdd:PRK08769  75 LQLVSFIPNRtgdklrteIVIEQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871 156 LMLPTIISRTQVIEF--PPLNaQALQQTFEQaGIAPNQAQmlRGLtnSVTQAQALLADDWLPQAAQALWRwfdqAVKGDP 233
Cdd:PRK08769 155 RLPATIRSRCQRLEFklPPAH-EALAWLLAQ-GVSERAAQ--EAL--DAARGHPGLAAQWLREDGLALRR----AVAQDL 224

                        250
                 ....*....|....*
gi 489736871 234 RSFVAVQVNLVGLAK 248
Cdd:PRK08769 225 EQIASGRAGAVDVAQ 239
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 29-165 1.45e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 56.15  E-value: 1.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  29 NHLAHAYLFAGMEGAGQPELAHWIAQRLFCLHINDGEPDGTCEECVRIANG-------------SHpdivtvapEGqrih 95
Cdd:PRK07764  34 GRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCVALAPGgpgsldvteidaaSH--------GG---- 101

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489736871  96 VDQVRYL--KAEFSksAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRT 165
Cdd:PRK07764 102 VDDARELreRAFFA--PAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDKVIGTIRSRT 171
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
 26-166 6.71e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 54.14  E-value: 6.71e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  26 IAQNHLAHAYLFAGMEGAGQPELAHWIAQRLFCL--HINDG---EPDGTCEECVRIANGSHPDIV-------TVAPEGQR 93
Cdd:PRK09111  40 FETGRIAQAFMLTGVRGVGKTTTARILARALNYEgpDGDGGptiDLCGVGEHCQAIMEGRHVDVLemdaashTGVDDIRE 119

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489736871  94 IhVDQVRYlkaefskSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTT--NKqlmLP-TIISRTQ 166
Cdd:PRK09111 120 I-IESVRY-------RPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATTeiRK---VPvTVLSRCQ 184
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
 116-170 2.73e-07

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 50.42  E-value: 2.73e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489736871 116 KLFIINdAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEF 170
Cdd:PRK08485  57 KIIVIA-APSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKR 110
44 PHA02544
clamp loader, small subunit; Provisional
 96-170 1.47e-06

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 49.22  E-value: 1.47e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489736871  96 VDQVRYLKAEFSKSA-VEGNRKLFIINDAEKM-TASAANSLLKFIEEPSGNVTALLLTTNKQLMLPTIISRTQVIEF 170
Cdd:PHA02544  81 IDFVRNRLTRFASTVsLTGGGKVIIIDEFDRLgLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCRVIDF 157
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
 82-164 1.65e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 48.69  E-value: 1.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  82 PDIVTVAPE------GQRIHVDQVRYLKAEFSKSAVEGNRKLFIINDAEKMTASAANSLLKFIEEPSGNVTALLLTTNKQ 155
Cdd:PRK06581  51 PDYHFIAREtsatsnAKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAA 130


                 ....*....
gi 489736871 156 LMLPTIISR 164
Cdd:PRK06581 131 SIISTIRSR 139
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 15-164 1.42e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 40.23  E-value: 1.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  15 QPRLLAAFKHIIAQNHLAHAYLFAGMEGAGQPELAhwiaqRLF--CLHINDG---EPDGTCEECVRIANGSHPDIvtvap 89
Cdd:PRK07994  21 QEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIA-----RLLakGLNCETGitaTPCGECDNCREIEQGRFVDL----- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489736871  90 egqrIHVDQVrylkaefSKSAVEGNR---------------KLFIInDAEKMTASAA-NSLLKFIEEPSGNVTALLLTTN 153
Cdd:PRK07994  91 ----IEIDAA-------SRTKVEDTRelldnvqyapargrfKVYLI-DEVHMLSRHSfNALLKTLEEPPEHVKFLLATTD 158

                        170
                 ....*....|..
gi 489736871 154 KQlMLP-TIISR 164
Cdd:PRK07994 159 PQ-KLPvTILSR 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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