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Conserved domains on  [gi|489516690|ref|WP_003421518|]
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MULTISPECIES: tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG [Pseudomonas syringae group]

Protein Classification

tRNA uridine-5-carboxymethylaminomethyl modification enzyme MnmG/GidA( domain architecture ID 11418560)

tRNA uridine-5-carboxymethylaminomethyl modification enzyme MnmG/GidA such as tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG, which is involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

CATH:  1.10.10.1800
EC:  2.1.1.-
Gene Ontology:  GO:0050660|GO:0002098|GO:0030488|GO:0008033
PubMed:  18565343|19801413|19767610|11544186
SCOP:  4006485

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MnmG COG0445
tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA [Translation, ribosomal ...
 1-625 0e+00

tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA [Translation, ribosomal structure and biogenesis]; tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA is part of the Pathway/BioSystem: tRNA modification


:

Pssm-ID: 440214 [Multi-domain]  Cd Length: 626  Bit Score: 1275.32  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   1 MDFPSRFEVIVIGGGHAGTEAALASARMGVKTLLLTHNVETLGQMSCNPAIGGIGKSHLVKEIDALGGAMAMATDKGGIQ 80
Cdd:COG0445    1 MYYPKEYDVIVVGGGHAGCEAALAAARMGAKTLLLTHNLDTIGQMSCNPAIGGIAKGHLVREIDALGGEMGRAADKTGIQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  81 FRVLNSRKGPAVRATRAQADRVLYKAAIRETLENQPNLWIFQQACDDLIVEQDQVRGVVTQMGMRIFADSVVLTTGTFLG 160
Cdd:COG0445   81 FRMLNTSKGPAVRAPRAQADRKLYRAAMRETLENQPNLDLIQGEVEDLIVEDGRVTGVVTADGIEFRAKAVVLTTGTFLN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 161 GLIHIGMQNYSGGRAGDPPSIALAQRLRELPLRVGRLKTGTPPRIDGRSVDFSVMTEQPGDTPIPVMSFLgNKEQHPPQV 240
Cdd:COG0445  161 GLIHIGEKSYPGGRAGEPPSVGLSESLRELGFELGRLKTGTPPRIDGRSIDFSKLEEQPGDEPPPPFSFL-TEKIHPPQI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 241 SCWITHTNARTHEIIASNLDRSPMYSGVIEGIGPRYCPSIEDKIHRFADKESHQVFIEPEGLTTHELYPNGISTSLPFDV 320
Cdd:COG0445  240 PCWITYTNEETHEIIRENLHRSPMYSGVIEGVGPRYCPSIEDKIVRFADKDRHQIFLEPEGLDTNEVYPNGISTSLPEDV 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 321 QLQIVQSIRGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRDS 400
Cdd:COG0445  320 QLAMLRSIPGLENAEILRPGYAIEYDYVDPTQLKPTLETKKIEGLFFAGQINGTTGYEEAAAQGLMAGINAALKAQGKEP 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 401 WCPRRDEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKGRELGLVDDARWAAFCTKRESIELEEQRL 480
Cdd:COG0445  400 FILDRSEAYIGVLIDDLVTKGTDEPYRMFTSRAEYRLLLRQDNADLRLTEKGYELGLVSDERYERFEEKKEAIEEEIERL 479

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 481 KSTWVRPGTEQGDAIAAHFGTPLTHEYNLLNLLTRPEIDYASLISITGQG-CIDPQVAEQVEIKTKYAGYIDRQQDEIAR 559
Cdd:COG0445  480 KSTRVTPNEEVNEGLEELGSSPLKRGVSLFDLLRRPEITYEDLAELDPELpDLDPEVAEQVEIEIKYEGYIERQEEEIEK 559

                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489516690 560 LRASEDTGLPEDIDYAAISGLSKEIQSKLGITRPQTLGQASRIPGVTPAAISLLMIHLKKRGAGRQ 625
Cdd:COG0445  560 LKRLENLKIPEDFDYDAIPGLSNEAREKLKKIRPETLGQASRISGVTPADISLLLVYLKRRRRRKK 625
 
Name Accession Description Interval E-value
MnmG COG0445
tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA [Translation, ribosomal ...
 1-625 0e+00

tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA [Translation, ribosomal structure and biogenesis]; tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440214 [Multi-domain]  Cd Length: 626  Bit Score: 1275.32  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   1 MDFPSRFEVIVIGGGHAGTEAALASARMGVKTLLLTHNVETLGQMSCNPAIGGIGKSHLVKEIDALGGAMAMATDKGGIQ 80
Cdd:COG0445    1 MYYPKEYDVIVVGGGHAGCEAALAAARMGAKTLLLTHNLDTIGQMSCNPAIGGIAKGHLVREIDALGGEMGRAADKTGIQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  81 FRVLNSRKGPAVRATRAQADRVLYKAAIRETLENQPNLWIFQQACDDLIVEQDQVRGVVTQMGMRIFADSVVLTTGTFLG 160
Cdd:COG0445   81 FRMLNTSKGPAVRAPRAQADRKLYRAAMRETLENQPNLDLIQGEVEDLIVEDGRVTGVVTADGIEFRAKAVVLTTGTFLN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 161 GLIHIGMQNYSGGRAGDPPSIALAQRLRELPLRVGRLKTGTPPRIDGRSVDFSVMTEQPGDTPIPVMSFLgNKEQHPPQV 240
Cdd:COG0445  161 GLIHIGEKSYPGGRAGEPPSVGLSESLRELGFELGRLKTGTPPRIDGRSIDFSKLEEQPGDEPPPPFSFL-TEKIHPPQI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 241 SCWITHTNARTHEIIASNLDRSPMYSGVIEGIGPRYCPSIEDKIHRFADKESHQVFIEPEGLTTHELYPNGISTSLPFDV 320
Cdd:COG0445  240 PCWITYTNEETHEIIRENLHRSPMYSGVIEGVGPRYCPSIEDKIVRFADKDRHQIFLEPEGLDTNEVYPNGISTSLPEDV 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 321 QLQIVQSIRGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRDS 400
Cdd:COG0445  320 QLAMLRSIPGLENAEILRPGYAIEYDYVDPTQLKPTLETKKIEGLFFAGQINGTTGYEEAAAQGLMAGINAALKAQGKEP 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 401 WCPRRDEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKGRELGLVDDARWAAFCTKRESIELEEQRL 480
Cdd:COG0445  400 FILDRSEAYIGVLIDDLVTKGTDEPYRMFTSRAEYRLLLRQDNADLRLTEKGYELGLVSDERYERFEEKKEAIEEEIERL 479

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 481 KSTWVRPGTEQGDAIAAHFGTPLTHEYNLLNLLTRPEIDYASLISITGQG-CIDPQVAEQVEIKTKYAGYIDRQQDEIAR 559
Cdd:COG0445  480 KSTRVTPNEEVNEGLEELGSSPLKRGVSLFDLLRRPEITYEDLAELDPELpDLDPEVAEQVEIEIKYEGYIERQEEEIEK 559

                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489516690 560 LRASEDTGLPEDIDYAAISGLSKEIQSKLGITRPQTLGQASRIPGVTPAAISLLMIHLKKRGAGRQ 625
Cdd:COG0445  560 LKRLENLKIPEDFDYDAIPGLSNEAREKLKKIRPETLGQASRISGVTPADISLLLVYLKRRRRRKK 625
gidA TIGR00136
glucose-inhibited division protein A; GidA, the longer of two forms of GidA-related proteins, ...
 7-621 0e+00

glucose-inhibited division protein A; GidA, the longer of two forms of GidA-related proteins, appears to be present in all complete eubacterial genomes so far, as well as Saccharomyces cerevisiae. A subset of these organisms have a closely related protein. GidA is absent in the Archaea. It appears to act with MnmE, in an alpha2/beta2 heterotetramer, in the 5-carboxymethylaminomethyl modification of uridine 34 in certain tRNAs. The shorter, related protein, previously called gid or gidA(S), is now called TrmFO (see model TIGR00137). [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 272927 [Multi-domain]  Cd Length: 616  Bit Score: 997.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690    7 FEVIVIGGGHAGTEAALASARMGVKTLLLTHNVETLGQMSCNPAIGGIGKSHLVKEIDALGGAMAMATDKGGIQFRVLNS 86
Cdd:TIGR00136   1 FDVIVIGGGHAGCEAALAAARLGAKTLLLTLNLDTIGKCSCNPAIGGPAKGILVKEIDALGGEMGKAADKTGLQFRVLNS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   87 RKGPAVRATRAQADRVLYKAAIRETLENQPNLWIFQQACDDLIVEQ-DQVRGVVTQMGMRIFADSVVLTTGTFLGGLIHI 165
Cdd:TIGR00136  81 SKGPAVRATRAQIDKILYQKWMRNQLENQPNLSLFQGEVEDLILEDnDEIKGVVTKDGNEFRAKAVIITTGTFLRGKIHI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  166 GMQNYSGGRAGDPPSIALAQRLRELPLRVGRLKTGTPPRIDGRSVDFSVMTEQPGDTPIPVMSFLgNKEQHPPQVSCWIT 245
Cdd:TIGR00136 161 GDKSYEAGRAGEQASYGLSTTLRELGFKTGRLKTGTPPRIDKRSIDFSKLEVQFGDTQPPAFSFT-NKNFLPQQLPCYLT 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  246 HTNARTHEIIASNLDRSPMYSGVIEGIGPRYCPSIEDKIHRFADKESHQVFIEPEGLTTHELYPNGISTSLPFDVQLQIV 325
Cdd:TIGR00136 240 HTNPKTHQIIRDNLHRSPMYSGSIEGNGPRYCPSIEDKVVRFADKERHQIFLEPEGLNSDEIYLNGLSTSLPEDVQLKII 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  326 QSIRGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRDSWCPRR 405
Cdd:TIGR00136 320 RSIPGLENAEILRPGYAIEYDYFDPTQLKPTLETKLIKGLFFAGQINGTTGYEEAAAQGLMAGINAALKLQNKEPFILKR 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  406 DEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKGRELGLVDDARWAAFCTKRESIELEEQRLKSTWV 485
Cdd:TIGR00136 400 NEAYIGVLIDDLVTKGTKEPYRMFTSRAEYRLLLREDNADFRLTEIGRELGLIDEDRYARFLKKKQNIEEEIERLKSTRL 479

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  486 RPGTEQGDAIAAHFGTPLTHEYNLLNLLTRPEIDYASLISIT-GQGCIDPQVAEQVEIKTKYAGYIDRQQDEIARLRASE 564
Cdd:TIGR00136 480 SPSKEVKEELKNLAQSPLKDEVSGYDLLKRPEMNLDKLTKLLpFLPPLDEEVLEQVEIEIKYEGYIKKQQQYIKKLDRLE 559

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 489516690  565 DTGLPEDIDYAAISGLSKEIQSKLGITRPQTLGQASRIPGVTPAAISLLMIHLKKRG 621
Cdd:TIGR00136 560 NVKIPADFDYRKIPGLSTEAREKLSKFRPLSLGQASRISGINPADISALLVYLKKQK 616
GIDA pfam01134
Glucose inhibited division protein A;
9-399 0e+00

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 693.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690    9 VIVIGGGHAGTEAALASARMGVKTLLLTHNVETLGQMSCNPAIGGIGKSHLVKEIDALGGAMAMATDKGGIQFRVLNSRK 88
Cdd:pfam01134   2 VIVIGGGHAGCEAALAAARMGAKVLLITHNTDTIAELSCNPSIGGIAKGHLVREIDALGGLMGKAADKTGIQFRMLNTSK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   89 GPAVRATRAQADRVLYKAAIRETLENQPNLWIFQQACDDLIVEQDQVRGVVTQMGMRIFADSVVLTTGTFLGGLIHIGMQ 168
Cdd:pfam01134  82 GPAVRALRAQVDRDLYSKEMTETLENHPNLTLIQGEVTDLIPENGKVKGVVTEDGEEYKAKAVVLATGTFLNGKIHIGLK 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  169 NYSGGRAGDPPSIALAQRLRELPLRVGRLKTGTPPRIDGRSVDFSVMTEQPGDTPIPVMSFLgNKEQHPPQVSCWITHTN 248
Cdd:pfam01134 162 CYPAGRLGELTSEGLSESLKELGFELGRFKTGTPPRIDKDSIDFSKLEEQPGDKPGPPFSYL-NCPMNKEQYPCFLTYTN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  249 ARTHEIIASNLDRSPMYSGVIEGIGPRYCPSIEDKIHRFADKESHQVFIEPEGLTTHELYPNGISTSLPFDVQLQIVQSI 328
Cdd:pfam01134 241 EATHEIIRDNLHRSPMFEGCIEGIGPRYCPSIEDKPVRFADKPYHQVFLEPEGLDTDEYYLVGFSTSLPEDVQKRVLRTI 320

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489516690  329 RGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRD 399
Cdd:pfam01134 321 PGLENAEIVRPGYAIEYDYIDPPQLLPTLETKKIPGLFFAGQINGTEGYEEAAAQGLLAGINAARKALGKE 391
PRK05335 PRK05335
tRNA (uracil-5-)-methyltransferase Gid; Reviewed
 8-399 4.47e-14

tRNA (uracil-5-)-methyltransferase Gid; Reviewed


Pssm-ID: 235416  Cd Length: 436  Bit Score: 74.80  E-value: 4.47e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   8 EVIVIGGGHAGTEAALASARMGVKTLL-------LT--HNVETLGQMSCNPAIGGIGKSH----LVKEIDALGGA-MAMA 73
Cdd:PRK05335   4 PVNVIGAGLAGSEAAWQLAKRGVPVELyemrpvkKTpaHHTDGFAELVCSNSFRSDSLTNavglLKEEMRRLGSLiMEAA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  74 tDKGgiqfrvlnsrkgpAVRATRAQA-DRVLYKAAIRETLENQPNLWIfqqacddliveqdqVRGVVTQmgmrIFADSVV 152
Cdd:PRK05335  84 -DAH-------------RVPAGGALAvDREGFSEYVTEALENHPLITV--------------IREEVTE----IPEDITI 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 153 LTTGtflgglihigmqnysggragdpP--SIALAQRLRELplrvgrlkTGTP---------PRIDGRSVDFSVmteqpgd 221
Cdd:PRK05335 132 IATG----------------------PltSDALAEAIKAL--------TGEDylyffdaaaPIVDKDSIDMDK------- 174

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 222 tpipvmsflgnkeqhppqvsCWIthtnartheiiASNLDRS-------PM----YSGVIEGIgprycpsIEDKIHRFADK 290
Cdd:PRK05335 175 --------------------VYL-----------ASRYDKGeadylncPMtkeeYEAFYEAL-------IAAEKAELKDF 216

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 291 ESHQVF-----IE----------------PEGLT---THE----------------LYpN--GISTSLPFDVQLQIVQSI 328
Cdd:PRK05335 217 EKEKYFegcmpIEvmaergretlrfgpmkPVGLTdprTGKrpyavvqlrqdnaagtLY-NivGFQTKLKWGEQKRVFRMI 295

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489516690 329 RGMENAHIVRPGYAIEYDYFD-PRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRD 399
Cdd:PRK05335 296 PGLENAEFVRYGVMHRNTFINsPKLLDPTLQLKKRPNLFFAGQITGVEGYVESAASGLLAGINAARLALGKE 367
 
Name Accession Description Interval E-value
MnmG COG0445
tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA [Translation, ribosomal ...
 1-625 0e+00

tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA [Translation, ribosomal structure and biogenesis]; tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440214 [Multi-domain]  Cd Length: 626  Bit Score: 1275.32  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   1 MDFPSRFEVIVIGGGHAGTEAALASARMGVKTLLLTHNVETLGQMSCNPAIGGIGKSHLVKEIDALGGAMAMATDKGGIQ 80
Cdd:COG0445    1 MYYPKEYDVIVVGGGHAGCEAALAAARMGAKTLLLTHNLDTIGQMSCNPAIGGIAKGHLVREIDALGGEMGRAADKTGIQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  81 FRVLNSRKGPAVRATRAQADRVLYKAAIRETLENQPNLWIFQQACDDLIVEQDQVRGVVTQMGMRIFADSVVLTTGTFLG 160
Cdd:COG0445   81 FRMLNTSKGPAVRAPRAQADRKLYRAAMRETLENQPNLDLIQGEVEDLIVEDGRVTGVVTADGIEFRAKAVVLTTGTFLN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 161 GLIHIGMQNYSGGRAGDPPSIALAQRLRELPLRVGRLKTGTPPRIDGRSVDFSVMTEQPGDTPIPVMSFLgNKEQHPPQV 240
Cdd:COG0445  161 GLIHIGEKSYPGGRAGEPPSVGLSESLRELGFELGRLKTGTPPRIDGRSIDFSKLEEQPGDEPPPPFSFL-TEKIHPPQI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 241 SCWITHTNARTHEIIASNLDRSPMYSGVIEGIGPRYCPSIEDKIHRFADKESHQVFIEPEGLTTHELYPNGISTSLPFDV 320
Cdd:COG0445  240 PCWITYTNEETHEIIRENLHRSPMYSGVIEGVGPRYCPSIEDKIVRFADKDRHQIFLEPEGLDTNEVYPNGISTSLPEDV 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 321 QLQIVQSIRGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRDS 400
Cdd:COG0445  320 QLAMLRSIPGLENAEILRPGYAIEYDYVDPTQLKPTLETKKIEGLFFAGQINGTTGYEEAAAQGLMAGINAALKAQGKEP 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 401 WCPRRDEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKGRELGLVDDARWAAFCTKRESIELEEQRL 480
Cdd:COG0445  400 FILDRSEAYIGVLIDDLVTKGTDEPYRMFTSRAEYRLLLRQDNADLRLTEKGYELGLVSDERYERFEEKKEAIEEEIERL 479

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 481 KSTWVRPGTEQGDAIAAHFGTPLTHEYNLLNLLTRPEIDYASLISITGQG-CIDPQVAEQVEIKTKYAGYIDRQQDEIAR 559
Cdd:COG0445  480 KSTRVTPNEEVNEGLEELGSSPLKRGVSLFDLLRRPEITYEDLAELDPELpDLDPEVAEQVEIEIKYEGYIERQEEEIEK 559

                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489516690 560 LRASEDTGLPEDIDYAAISGLSKEIQSKLGITRPQTLGQASRIPGVTPAAISLLMIHLKKRGAGRQ 625
Cdd:COG0445  560 LKRLENLKIPEDFDYDAIPGLSNEAREKLKKIRPETLGQASRISGVTPADISLLLVYLKRRRRRKK 625
gidA TIGR00136
glucose-inhibited division protein A; GidA, the longer of two forms of GidA-related proteins, ...
 7-621 0e+00

glucose-inhibited division protein A; GidA, the longer of two forms of GidA-related proteins, appears to be present in all complete eubacterial genomes so far, as well as Saccharomyces cerevisiae. A subset of these organisms have a closely related protein. GidA is absent in the Archaea. It appears to act with MnmE, in an alpha2/beta2 heterotetramer, in the 5-carboxymethylaminomethyl modification of uridine 34 in certain tRNAs. The shorter, related protein, previously called gid or gidA(S), is now called TrmFO (see model TIGR00137). [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 272927 [Multi-domain]  Cd Length: 616  Bit Score: 997.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690    7 FEVIVIGGGHAGTEAALASARMGVKTLLLTHNVETLGQMSCNPAIGGIGKSHLVKEIDALGGAMAMATDKGGIQFRVLNS 86
Cdd:TIGR00136   1 FDVIVIGGGHAGCEAALAAARLGAKTLLLTLNLDTIGKCSCNPAIGGPAKGILVKEIDALGGEMGKAADKTGLQFRVLNS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   87 RKGPAVRATRAQADRVLYKAAIRETLENQPNLWIFQQACDDLIVEQ-DQVRGVVTQMGMRIFADSVVLTTGTFLGGLIHI 165
Cdd:TIGR00136  81 SKGPAVRATRAQIDKILYQKWMRNQLENQPNLSLFQGEVEDLILEDnDEIKGVVTKDGNEFRAKAVIITTGTFLRGKIHI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  166 GMQNYSGGRAGDPPSIALAQRLRELPLRVGRLKTGTPPRIDGRSVDFSVMTEQPGDTPIPVMSFLgNKEQHPPQVSCWIT 245
Cdd:TIGR00136 161 GDKSYEAGRAGEQASYGLSTTLRELGFKTGRLKTGTPPRIDKRSIDFSKLEVQFGDTQPPAFSFT-NKNFLPQQLPCYLT 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  246 HTNARTHEIIASNLDRSPMYSGVIEGIGPRYCPSIEDKIHRFADKESHQVFIEPEGLTTHELYPNGISTSLPFDVQLQIV 325
Cdd:TIGR00136 240 HTNPKTHQIIRDNLHRSPMYSGSIEGNGPRYCPSIEDKVVRFADKERHQIFLEPEGLNSDEIYLNGLSTSLPEDVQLKII 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  326 QSIRGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRDSWCPRR 405
Cdd:TIGR00136 320 RSIPGLENAEILRPGYAIEYDYFDPTQLKPTLETKLIKGLFFAGQINGTTGYEEAAAQGLMAGINAALKLQNKEPFILKR 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  406 DEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKGRELGLVDDARWAAFCTKRESIELEEQRLKSTWV 485
Cdd:TIGR00136 400 NEAYIGVLIDDLVTKGTKEPYRMFTSRAEYRLLLREDNADFRLTEIGRELGLIDEDRYARFLKKKQNIEEEIERLKSTRL 479

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  486 RPGTEQGDAIAAHFGTPLTHEYNLLNLLTRPEIDYASLISIT-GQGCIDPQVAEQVEIKTKYAGYIDRQQDEIARLRASE 564
Cdd:TIGR00136 480 SPSKEVKEELKNLAQSPLKDEVSGYDLLKRPEMNLDKLTKLLpFLPPLDEEVLEQVEIEIKYEGYIKKQQQYIKKLDRLE 559

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 489516690  565 DTGLPEDIDYAAISGLSKEIQSKLGITRPQTLGQASRIPGVTPAAISLLMIHLKKRG 621
Cdd:TIGR00136 560 NVKIPADFDYRKIPGLSTEAREKLSKFRPLSLGQASRISGINPADISALLVYLKKQK 616
GIDA pfam01134
Glucose inhibited division protein A;
9-399 0e+00

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 693.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690    9 VIVIGGGHAGTEAALASARMGVKTLLLTHNVETLGQMSCNPAIGGIGKSHLVKEIDALGGAMAMATDKGGIQFRVLNSRK 88
Cdd:pfam01134   2 VIVIGGGHAGCEAALAAARMGAKVLLITHNTDTIAELSCNPSIGGIAKGHLVREIDALGGLMGKAADKTGIQFRMLNTSK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   89 GPAVRATRAQADRVLYKAAIRETLENQPNLWIFQQACDDLIVEQDQVRGVVTQMGMRIFADSVVLTTGTFLGGLIHIGMQ 168
Cdd:pfam01134  82 GPAVRALRAQVDRDLYSKEMTETLENHPNLTLIQGEVTDLIPENGKVKGVVTEDGEEYKAKAVVLATGTFLNGKIHIGLK 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  169 NYSGGRAGDPPSIALAQRLRELPLRVGRLKTGTPPRIDGRSVDFSVMTEQPGDTPIPVMSFLgNKEQHPPQVSCWITHTN 248
Cdd:pfam01134 162 CYPAGRLGELTSEGLSESLKELGFELGRFKTGTPPRIDKDSIDFSKLEEQPGDKPGPPFSYL-NCPMNKEQYPCFLTYTN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  249 ARTHEIIASNLDRSPMYSGVIEGIGPRYCPSIEDKIHRFADKESHQVFIEPEGLTTHELYPNGISTSLPFDVQLQIVQSI 328
Cdd:pfam01134 241 EATHEIIRDNLHRSPMFEGCIEGIGPRYCPSIEDKPVRFADKPYHQVFLEPEGLDTDEYYLVGFSTSLPEDVQKRVLRTI 320

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489516690  329 RGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRD 399
Cdd:pfam01134 321 PGLENAEIVRPGYAIEYDYIDPPQLLPTLETKKIPGLFFAGQINGTEGYEEAAAQGLLAGINAARKALGKE 391
GIDA_C pfam13932
tRNA modifying enzyme MnmG/GidA C-terminal domain; The GidA associated domain is a domain that ...
 401-614 1.99e-119

tRNA modifying enzyme MnmG/GidA C-terminal domain; The GidA associated domain is a domain that has been identified at the C-terminus of protein GidA. It consists of several helices, the last three being rather short and forming small bundle. GidA is an tRNA modification enzyme found in bacteria and mitochondrial. Based on mutational analysis this domain has been suggested to be implicated in binding of the D-stem of tRNA and to be responsible for the interaction with protein MnmE. Structures of GidA in complex with either tRNA or MnmE are missing. Reported to bind to Pfam family MnmE, pfam12631.


Pssm-ID: 464049 [Multi-domain]  Cd Length: 214  Bit Score: 353.61  E-value: 1.99e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  401 WCPRRDEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKGRELGLVDDARWAAFCTKRESIELEEQRL 480
Cdd:pfam13932   1 LILSRSEAYIGVLIDDLVTKGTSEPYRMFTSRAEYRLLLRQDNADLRLTEKGRELGLVSDERYERFEEKKEAIEEEIERL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  481 KSTWVRPGTEQGDAIAAHfGTPLTHEYNLLNLLTRPEIDYASLIS-ITGQGCIDPQVAEQVEIKTKYAGYIDRQQDEIAR 559
Cdd:pfam13932  81 KSTRLSPSEWNNALLELG-SAPLGTGRSAFDLLRRPEVTYEDLAAlIPELAPLDPEVLEQVEIEAKYEGYIERQEAEIEK 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 489516690  560 LRASEDTGLPEDIDYAAISGLSKEIQSKLGITRPQTLGQASRIPGVTPAAISLLM 614
Cdd:pfam13932 160 FKRLENLKIPEDLDYDAIPGLSNEAREKLNKIRPETIGQASRISGVTPADISVLL 214
PRK05335 PRK05335
tRNA (uracil-5-)-methyltransferase Gid; Reviewed
 8-399 4.47e-14

tRNA (uracil-5-)-methyltransferase Gid; Reviewed


Pssm-ID: 235416  Cd Length: 436  Bit Score: 74.80  E-value: 4.47e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   8 EVIVIGGGHAGTEAALASARMGVKTLL-------LT--HNVETLGQMSCNPAIGGIGKSH----LVKEIDALGGA-MAMA 73
Cdd:PRK05335   4 PVNVIGAGLAGSEAAWQLAKRGVPVELyemrpvkKTpaHHTDGFAELVCSNSFRSDSLTNavglLKEEMRRLGSLiMEAA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  74 tDKGgiqfrvlnsrkgpAVRATRAQA-DRVLYKAAIRETLENQPNLWIfqqacddliveqdqVRGVVTQmgmrIFADSVV 152
Cdd:PRK05335  84 -DAH-------------RVPAGGALAvDREGFSEYVTEALENHPLITV--------------IREEVTE----IPEDITI 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 153 LTTGtflgglihigmqnysggragdpP--SIALAQRLRELplrvgrlkTGTP---------PRIDGRSVDFSVmteqpgd 221
Cdd:PRK05335 132 IATG----------------------PltSDALAEAIKAL--------TGEDylyffdaaaPIVDKDSIDMDK------- 174

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 222 tpipvmsflgnkeqhppqvsCWIthtnartheiiASNLDRS-------PM----YSGVIEGIgprycpsIEDKIHRFADK 290
Cdd:PRK05335 175 --------------------VYL-----------ASRYDKGeadylncPMtkeeYEAFYEAL-------IAAEKAELKDF 216

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 291 ESHQVF-----IE----------------PEGLT---THE----------------LYpN--GISTSLPFDVQLQIVQSI 328
Cdd:PRK05335 217 EKEKYFegcmpIEvmaergretlrfgpmkPVGLTdprTGKrpyavvqlrqdnaagtLY-NivGFQTKLKWGEQKRVFRMI 295

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489516690 329 RGMENAHIVRPGYAIEYDYFD-PRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRD 399
Cdd:PRK05335 296 PGLENAEFVRYGVMHRNTFINsPKLLDPTLQLKKRPNLFFAGQITGVEGYVESAASGLLAGINAARLALGKE 367
TrmFO COG1206
Folate-dependent tRNA-U54 methylase TrmFO/GidA [Translation, ribosomal structure and ...
 8-399 1.43e-12

Folate-dependent tRNA-U54 methylase TrmFO/GidA [Translation, ribosomal structure and biogenesis]; Folate-dependent tRNA-U54 methylase TrmFO/GidA is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440819  Cd Length: 436  Bit Score: 70.09  E-value: 1.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   8 EVIVIGGGHAGTEAALASARMGVKTLL-------LT--HNVETLGQMSC---------NPAIGgigkshLVK-EIDALGG 68
Cdd:COG1206    3 PVTVIGGGLAGSEAAWQLAERGVPVRLyemrpvkMTpaHKTDGFAELVCsnslrsddlTNAVG------LLKeEMRRLGS 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  69 ---AMAMATdkggiqfrvlnsrkgpAVRATRAQA-DRVLYKAAIRETLENQPNLWIfqqacddliveqdqVRGVVTQmgm 144
Cdd:COG1206   77 limAAADAH----------------RVPAGGALAvDREGFSAAVTEKLENHPNITV--------------VREEVTE--- 123

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 145 rIFAD-SVVLTTGtflgglihigmqnysggragdpP--SIALAQRLRELplrvgrlkTGTP---------PRIDGRSVDF 212
Cdd:COG1206  124 -IPEDgPVIIATG----------------------PltSDALAEAIQEL--------TGEEylyfydaiaPIVDADSIDM 172

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 213 SVmteqpgdtpipvmsflgnkeqhppqvsCWIthtnartheiiASnldrspmysgviegigpRY---------CPSIEDK 283
Cdd:COG1206  173 DK---------------------------AFR-----------AS-----------------RYdkgeadylnCPMTKEE 197

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 284 IHRF------ADK------ESHQVF-----IE----------------PEGLT---THE----------------LYpN- 310
Cdd:COG1206  198 YEAFyeallaAEKvelkdfEKEKYFegclpIEvmarrgrdtlrfgpmkPVGLTdprTGKrpyavvqlrqenaegtLY-Nl 276

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690 311 -GISTSLPFDVQLQIVQSIRGMENAHIVRPGyAIEYDYF--DPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLA 387
Cdd:COG1206  277 vGFQTKLKWGEQKRVFRMIPGLENAEFVRYG-VMHRNTFinSPKLLDPTLQLKARPNLFFAGQITGVEGYVESAASGLLA 355

                        490
                 ....*....|..
gi 489516690 388 GTNAALRAQGRD 399
Cdd:COG1206  356 GINAARLLLGKE 367
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 9-156 6.52e-08

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 55.31  E-value: 6.52e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690    9 VIVIGGGHAGTEAALASARMGVKTLLlthnVETlgqmscNPAIGGIGKShlvkeidALGGAMAMATDK-----GGI--QF 81
Cdd:pfam12831   2 VVVVGGGPAGVAAAIAAARAGAKVLL----VER------RGFLGGMLTS-------GLVGPDMGFYLNkeqvvGGIarEF 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   82 RVLNSRKGPAVRATRAQADRVLY-----KAAIRETLEnQPNL-WIFQQACDDLIVEQDQVRGVVTQM---GMRIFADSVV 152
Cdd:pfam12831  65 RQRLRARGGLPGPYGLRGGWVPFdpevaKAVLDEMLA-EAGVtVLLHTRVVGVVKEGGRITGVTVETkggRITIRAKVFI 143


                  ....
gi 489516690  153 LTTG 156
Cdd:pfam12831 144 DATG 147
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
6-46 7.11e-04

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 42.53  E-value: 7.11e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 489516690   6 RFEVIVIGGGHAGTEAALASARMGVKTLLLTHNVETLGQMS 46
Cdd:PRK05329   2 KFDVLVIGGGLAGLTAALAAAEAGKRVALVAKGQGALHFSS 42
GlpB COG3075
Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];
6-42 9.91e-04

Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];


Pssm-ID: 442309  Cd Length: 415  Bit Score: 42.09  E-value: 9.91e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 489516690   6 RFEVIVIGGGHAGTEAALASARMGVKTLLLTHNVETL 42
Cdd:COG3075    2 KFDVVVIGGGLAGLTAAIRAAEAGLRVAIVSAGQSAL 38
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 7-156 9.93e-04

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 42.13  E-value: 9.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   7 FEVIVIGGGHAGTEAALASARMGVKTLLLTHnVETLG----------QMSCNPAIGGIGK----SH---LVKEIDALG-- 67
Cdd:COG1053    4 YDVVVVGSGGAGLRAALEAAEAGLKVLVLEK-VPPRGghtaaaqggiNAAGTNVQKAAGEdspeEHfydTVKGGDGLAdq 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690  68 --------GAMAMA--TDKGGIQFRV-----LNSRKGPAVRATRAQADRV-------LYKAAIRETLEnqpnlwIFQQA- 124
Cdd:COG1053   83 dlvealaeEAPEAIdwLEAQGVPFSRtpdgrLPQFGGHSVGRTCYAGDGTghallatLYQAALRLGVE------IFTETe 156

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 489516690 125 CDDLIVEQDQVRGVVTQMG----MRIFADSVVLTTG 156
Cdd:COG1053  157 VLDLIVDDGRVVGVVARDRtgeiVRIRAKAVVLATG 192
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 7-35 2.26e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 40.38  E-value: 2.26e-03
                          10        20
                  ....*....|....*....|....*....
gi 489516690    7 FEVIVIGGGHAGTEAALASARMGVKTLLL 35
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLI 29
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
9-53 2.90e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 40.61  E-value: 2.90e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 489516690   9 VIVIGGGHAGTEAALASARMGVKTLLlthnVETlgqmscNPAIGG 53
Cdd:COG1148  143 ALVIGGGIAGMTAALELAEQGYEVYL----VEK------EPELGG 177
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
7-156 3.05e-03

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 40.10  E-value: 3.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489516690   7 FEVIVIGGGHAGTEAALASARMGVKTLLLthnvetlgqmscnpaiggigkshlvkEIDALGGAMAMATD-------KGGI 79
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIYAARAGLKTLVI--------------------------EGGEPGGQLATTKEienypgfPEGI 54

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489516690  80 QfrvlnsrkGPA-VRATRAQADRvlYKAAIR-ETLENqpnlwifqqacddlIVEQDQVRGVVTQMGMRIFADSVVLTTG 156
Cdd:COG0492   55 S--------GPElAERLREQAER--FGAEILlEEVTS--------------VDKDDGPFRVTTDDGTEYEAKAVIIATG 109
HI0933_like pfam03486
HI0933-like protein;
7-38 5.83e-03

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 39.49  E-value: 5.83e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 489516690    7 FEVIVIGGGHAGTEAALASARMGVKTLLLTHN 38
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEKG 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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