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Conserved domains on  [gi|489497937|ref|WP_003402848|]
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MULTISPECIES: cytochrome c biogenesis protein ResB [Mycobacterium]

Protein Classification

cytochrome c biogenesis protein ResB( domain architecture ID 10003552)

cytochrome c biogenesis protein ResB (also called CcsB and Ccs1) is essential for the biogenesis of c-type cytochromes, and may be required at the heme attachment step

Gene Ontology:  GO:0017004|GO:0016020
PubMed:  9395519

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ResB COG1333
Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational ...
2-509 3.30e-171

Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440944  Cd Length: 479  Bit Score: 492.09  E-value: 3.30e-171
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937   2 WRSLTSMGTALVLLFLLALAAIPGALLPQRGLNAAKVDDYLAAH-PLIGPWLDELQAFDVFSSFWFTAIYVLLFVSLVGC 80
Cdd:COG1333   15 WRQLTSMRTALFLLLLLAVAAIPGTLLPQRSPDPAGVTQYLADYgPTLGPILDRLGLFDVYSSWWFSAIYLLLFISLIGC 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  81 LAPRTIEHARSLRATPVAAPRN-LARLPKHAHARLAGEPAALAATITGRLR--GWRSITRQQGDSVEVSAEKGYLREFGN 157
Cdd:COG1333   95 SIPRLPPHWKALRAQPPRTPRRfLKRLPHHAELTVDASPDEVLERAAALLRkrGYRVREREDDGGVSVSAEKGYLRELGN 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 158 LVFHFALLGLLVAVAVGKLFGYEGNVIVIAdgGPGFCSasPAAFDSFragntvDGTSLHPICVRVNNFQAHYLPSGQATS 237
Cdd:COG1333  175 LVFHLSLLGILIGVALGSLFGYRGQVIVVE--GETFAT--LVGYDSF------DGDQLLPFSVRLDDFTVEYYDNGQPKD 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 238 FAADIDYQADPATAdliansWRPYRLQVNHPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTST-VQWRPDNpqtllsagv 316
Cdd:COG1333  245 FQSDVTVTEGGGGE------VKEATIRVNHPLRYDGYRVYQSGYGYAPSVTVRDKDGGVVFGGpVPFLPQD--------- 309
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 317 vridppaGSYPNPDERRKHQIAIQgLLAPTEQLDGT-LLSSRFPALNAPAVAIDIYRGDTGLDSGRPqslftldhrlieq 395
Cdd:COG1333  310 -------SSIKVPDNGLPEQLGLE-FFLPTAALDGDgVPTSKSPDPNNPALVLKVYRGDLGLDTGVP------------- 368
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 396 grlvkeKRVNLRAGQQVRIDQGPaagTVVRFD--GAVPFVNLQVSHDPGQSWVLVFAITMMAGLLVSLLVRRRRVWARIT 473
Cdd:COG1333  369 ------ARSFLAPGQTVELPDGL---GTITFDgfGVKRFTGLQVSKDPGQPLVLLGAILLLLGLILSLYVRRRRVWVRVT 439
                        490       500       510
                 ....*....|....*....|....*....|....*.
gi 489497937 474 PTTAGTVNVELGGLTRTDNSGWGAEFERLTGRLLAG 509
Cdd:COG1333  440 PDGDGGTVVEVAGLARKNDAGLEKEFDRLAAALDQA 475
 
Name Accession Description Interval E-value
ResB COG1333
Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational ...
2-509 3.30e-171

Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440944  Cd Length: 479  Bit Score: 492.09  E-value: 3.30e-171
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937   2 WRSLTSMGTALVLLFLLALAAIPGALLPQRGLNAAKVDDYLAAH-PLIGPWLDELQAFDVFSSFWFTAIYVLLFVSLVGC 80
Cdd:COG1333   15 WRQLTSMRTALFLLLLLAVAAIPGTLLPQRSPDPAGVTQYLADYgPTLGPILDRLGLFDVYSSWWFSAIYLLLFISLIGC 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  81 LAPRTIEHARSLRATPVAAPRN-LARLPKHAHARLAGEPAALAATITGRLR--GWRSITRQQGDSVEVSAEKGYLREFGN 157
Cdd:COG1333   95 SIPRLPPHWKALRAQPPRTPRRfLKRLPHHAELTVDASPDEVLERAAALLRkrGYRVREREDDGGVSVSAEKGYLRELGN 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 158 LVFHFALLGLLVAVAVGKLFGYEGNVIVIAdgGPGFCSasPAAFDSFragntvDGTSLHPICVRVNNFQAHYLPSGQATS 237
Cdd:COG1333  175 LVFHLSLLGILIGVALGSLFGYRGQVIVVE--GETFAT--LVGYDSF------DGDQLLPFSVRLDDFTVEYYDNGQPKD 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 238 FAADIDYQADPATAdliansWRPYRLQVNHPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTST-VQWRPDNpqtllsagv 316
Cdd:COG1333  245 FQSDVTVTEGGGGE------VKEATIRVNHPLRYDGYRVYQSGYGYAPSVTVRDKDGGVVFGGpVPFLPQD--------- 309
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 317 vridppaGSYPNPDERRKHQIAIQgLLAPTEQLDGT-LLSSRFPALNAPAVAIDIYRGDTGLDSGRPqslftldhrlieq 395
Cdd:COG1333  310 -------SSIKVPDNGLPEQLGLE-FFLPTAALDGDgVPTSKSPDPNNPALVLKVYRGDLGLDTGVP------------- 368
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 396 grlvkeKRVNLRAGQQVRIDQGPaagTVVRFD--GAVPFVNLQVSHDPGQSWVLVFAITMMAGLLVSLLVRRRRVWARIT 473
Cdd:COG1333  369 ------ARSFLAPGQTVELPDGL---GTITFDgfGVKRFTGLQVSKDPGQPLVLLGAILLLLGLILSLYVRRRRVWVRVT 439
                        490       500       510
                 ....*....|....*....|....*....|....*.
gi 489497937 474 PTTAGTVNVELGGLTRTDNSGWGAEFERLTGRLLAG 509
Cdd:COG1333  440 PDGDGGTVVEVAGLARKNDAGLEKEFDRLAAALDQA 475
ResB pfam05140
ResB-like family; This family includes both ResB and cytochrome c biogenesis proteins. ...
23-500 4.18e-171

ResB-like family; This family includes both ResB and cytochrome c biogenesis proteins. Mutations in ResB indicate that they are essential for growth. ResB is predicted to be a transmembrane protein.


Pssm-ID: 428331  Cd Length: 445  Bit Score: 490.57  E-value: 4.18e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937   23 IPGALLPQRGLNAAKVDDYLAAHPLIGPWLDELQAFDVFSSFWFTAIYVLLFVSLVGCLAPRTIEHARSLRAT-PVAAPR 101
Cdd:pfam05140  16 IPGTVLPQRQPSLNYVAQYIADGPFWAPWFDRLGLFDVYSSWWFLAIYLLLFVSLVGCILPRLPPHLRALRSQrPPRAPR 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  102 NLARLPKHAHARLAGEPAALAATITGRL--RGWRSITRQQGDSveVSAEKGYLREFGNLVFHFALLGLLVAVAVGKLFGY 179
Cdd:pfam05140  96 RLKRLPHHAEFEVADAPEEAAERAAALLkrRGYRVRVEEGGGS--LAAEKGYLRRLGNLVFHLALLVILVGGLLGSLFGY 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  180 EGNVIVIAdgGPGFCSASPAafdSFRAGNTVDGTslhPICVRVNNFQAHYLPSGQATSFAADIDYQADPATAdliansWR 259
Cdd:pfam05140 174 RGNVIVPE--GQGFCNTFLA---SFRDGALVDPL---PFSVRLDKFTVEYYDTGQPKSFESDVTVTDGGKGE------VR 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  260 PYRLQVNHPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTSTVqwrpDNPQTLLSAGVvridppagsypnpderRKHQIAI 339
Cdd:pfam05140 240 EATIRVNHPLRYDGVRVYQSSYGPAPVFTVRDPDGEVRTGPV----PQDGNFTSSGV----------------RKPQLAF 299
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  340 QGLLAPTEQLDGTLLSSrFPALNAPAVAIDIYRGDTGLDSGRPQSLFTLDHRLIEQGRLVKEKRVnlragqqvridqGPA 419
Cdd:pfam05140 300 QGLFLPTAALGEGFLSL-FPALNDPALALDAYRGDLGLDAGGPQSVYSLDTTLFELGQLNADRYG------------APY 366
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  420 AGTVVRFDgAVPFVNLQVSHDPGQSWVLVFAITMMAGLLVSLLVRRRRVWARITPTTAGTVnVELGGLTRTDNSGWGAEF 499
Cdd:pfam05140 367 LLPLDDFD-VKQFSGLQVSRDPGQPLVLVGAVLLVLGLFLSLYVRHRRVWVRVTPGDGGTV-VEVAGLARKNWAGFGEEF 444

                  .
gi 489497937  500 E 500
Cdd:pfam05140 445 D 445
 
Name Accession Description Interval E-value
ResB COG1333
Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational ...
2-509 3.30e-171

Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440944  Cd Length: 479  Bit Score: 492.09  E-value: 3.30e-171
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937   2 WRSLTSMGTALVLLFLLALAAIPGALLPQRGLNAAKVDDYLAAH-PLIGPWLDELQAFDVFSSFWFTAIYVLLFVSLVGC 80
Cdd:COG1333   15 WRQLTSMRTALFLLLLLAVAAIPGTLLPQRSPDPAGVTQYLADYgPTLGPILDRLGLFDVYSSWWFSAIYLLLFISLIGC 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  81 LAPRTIEHARSLRATPVAAPRN-LARLPKHAHARLAGEPAALAATITGRLR--GWRSITRQQGDSVEVSAEKGYLREFGN 157
Cdd:COG1333   95 SIPRLPPHWKALRAQPPRTPRRfLKRLPHHAELTVDASPDEVLERAAALLRkrGYRVREREDDGGVSVSAEKGYLRELGN 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 158 LVFHFALLGLLVAVAVGKLFGYEGNVIVIAdgGPGFCSasPAAFDSFragntvDGTSLHPICVRVNNFQAHYLPSGQATS 237
Cdd:COG1333  175 LVFHLSLLGILIGVALGSLFGYRGQVIVVE--GETFAT--LVGYDSF------DGDQLLPFSVRLDDFTVEYYDNGQPKD 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 238 FAADIDYQADPATAdliansWRPYRLQVNHPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTST-VQWRPDNpqtllsagv 316
Cdd:COG1333  245 FQSDVTVTEGGGGE------VKEATIRVNHPLRYDGYRVYQSGYGYAPSVTVRDKDGGVVFGGpVPFLPQD--------- 309
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 317 vridppaGSYPNPDERRKHQIAIQgLLAPTEQLDGT-LLSSRFPALNAPAVAIDIYRGDTGLDSGRPqslftldhrlieq 395
Cdd:COG1333  310 -------SSIKVPDNGLPEQLGLE-FFLPTAALDGDgVPTSKSPDPNNPALVLKVYRGDLGLDTGVP------------- 368
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937 396 grlvkeKRVNLRAGQQVRIDQGPaagTVVRFD--GAVPFVNLQVSHDPGQSWVLVFAITMMAGLLVSLLVRRRRVWARIT 473
Cdd:COG1333  369 ------ARSFLAPGQTVELPDGL---GTITFDgfGVKRFTGLQVSKDPGQPLVLLGAILLLLGLILSLYVRRRRVWVRVT 439
                        490       500       510
                 ....*....|....*....|....*....|....*.
gi 489497937 474 PTTAGTVNVELGGLTRTDNSGWGAEFERLTGRLLAG 509
Cdd:COG1333  440 PDGDGGTVVEVAGLARKNDAGLEKEFDRLAAALDQA 475
ResB pfam05140
ResB-like family; This family includes both ResB and cytochrome c biogenesis proteins. ...
23-500 4.18e-171

ResB-like family; This family includes both ResB and cytochrome c biogenesis proteins. Mutations in ResB indicate that they are essential for growth. ResB is predicted to be a transmembrane protein.


Pssm-ID: 428331  Cd Length: 445  Bit Score: 490.57  E-value: 4.18e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937   23 IPGALLPQRGLNAAKVDDYLAAHPLIGPWLDELQAFDVFSSFWFTAIYVLLFVSLVGCLAPRTIEHARSLRAT-PVAAPR 101
Cdd:pfam05140  16 IPGTVLPQRQPSLNYVAQYIADGPFWAPWFDRLGLFDVYSSWWFLAIYLLLFVSLVGCILPRLPPHLRALRSQrPPRAPR 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  102 NLARLPKHAHARLAGEPAALAATITGRL--RGWRSITRQQGDSveVSAEKGYLREFGNLVFHFALLGLLVAVAVGKLFGY 179
Cdd:pfam05140  96 RLKRLPHHAEFEVADAPEEAAERAAALLkrRGYRVRVEEGGGS--LAAEKGYLRRLGNLVFHLALLVILVGGLLGSLFGY 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  180 EGNVIVIAdgGPGFCSASPAafdSFRAGNTVDGTslhPICVRVNNFQAHYLPSGQATSFAADIDYQADPATAdliansWR 259
Cdd:pfam05140 174 RGNVIVPE--GQGFCNTFLA---SFRDGALVDPL---PFSVRLDKFTVEYYDTGQPKSFESDVTVTDGGKGE------VR 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  260 PYRLQVNHPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTSTVqwrpDNPQTLLSAGVvridppagsypnpderRKHQIAI 339
Cdd:pfam05140 240 EATIRVNHPLRYDGVRVYQSSYGPAPVFTVRDPDGEVRTGPV----PQDGNFTSSGV----------------RKPQLAF 299
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  340 QGLLAPTEQLDGTLLSSrFPALNAPAVAIDIYRGDTGLDSGRPQSLFTLDHRLIEQGRLVKEKRVnlragqqvridqGPA 419
Cdd:pfam05140 300 QGLFLPTAALGEGFLSL-FPALNDPALALDAYRGDLGLDAGGPQSVYSLDTTLFELGQLNADRYG------------APY 366
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489497937  420 AGTVVRFDgAVPFVNLQVSHDPGQSWVLVFAITMMAGLLVSLLVRRRRVWARITPTTAGTVnVELGGLTRTDNSGWGAEF 499
Cdd:pfam05140 367 LLPLDDFD-VKQFSGLQVSRDPGQPLVLVGAVLLVLGLFLSLYVRHRRVWVRVTPGDGGTV-VEVAGLARKNWAGFGEEF 444

                  .
gi 489497937  500 E 500
Cdd:pfam05140 445 D 445
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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