NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|489350042|ref|WP_003257130|]
View 

MULTISPECIES: NAD(P)/FAD-dependent oxidoreductase [Bacillus]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11441266)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; belongs to the pyridine nucleotide-disulfide oxidoreductase superfamily

CATH:  3.30.390.30
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0000166
PubMed:  38537870
SCOP:  4000121

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
3-394 2.98e-128

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


:

Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 375.25  E-value: 2.98e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   3 KNFVIIGSGVAAVNAAKTIREYDKGSNIFIFGEEPLLPYKRIKLSKDLYSDLHSEKVLIKKKKWYQDNHISFFINTKVVK 82
Cdd:COG1251    2 MRIVIIGAGMAGVRAAEELRKLDPDGEITVIGAEPHPPYNRPPLSKVLAGETDEEDLLLRPADFYEENGIDLRLGTRVTA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  83 INTDEQFIVTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLEDKESVVTIGGGVQGLETAWSI 162
Cdd:COG1251   82 IDRAARTVTLADGETLPYDKLVLATGSRPRVPPIPGADLPGVFTLRTLDDADALRAALAPGKRVVVIGGGLIGLEAAAAL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 163 LKAGKKVSIVEVAPLLMRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQINCDSIVYSIGVTPN 242
Cdd:COG1251  162 RKRGLEVTVVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGTGVTEIEGDDRVTGVRLADGEELPADLVVVAIGVRPN 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 243 TKLVHDTAIKLNRGIVVDEKMRTNIDSVYAAGDVAEVNNEIEG-----LWGTALEQGRVAGSNMVSKTAIYKKEIPTTIF 317
Cdd:COG1251  242 TELARAAGLAVDRGIVVDDYLRTSDPDIYAAGDCAEHPGPVYGrrvleLVAPAYEQARVAAANLAGGPAAYEGSVPSTKL 321

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489350042 318 NAFNVSLFSIGVVNKEqcDTTIVEED-GKEKYTRLFIKDNKIVGVISLEGVAASIPYKSAIEKHVSLEGIDLLNTNIS 394
Cdd:COG1251  322 KVFGVDVASAGDAEGD--EEVVVRGDpARGVYKKLVLRDGRLVGAVLVGDTSDAGALRQLIKNGRPLPPRALLDAALP 397
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
3-394 2.98e-128

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 375.25  E-value: 2.98e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   3 KNFVIIGSGVAAVNAAKTIREYDKGSNIFIFGEEPLLPYKRIKLSKDLYSDLHSEKVLIKKKKWYQDNHISFFINTKVVK 82
Cdd:COG1251    2 MRIVIIGAGMAGVRAAEELRKLDPDGEITVIGAEPHPPYNRPPLSKVLAGETDEEDLLLRPADFYEENGIDLRLGTRVTA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  83 INTDEQFIVTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLEDKESVVTIGGGVQGLETAWSI 162
Cdd:COG1251   82 IDRAARTVTLADGETLPYDKLVLATGSRPRVPPIPGADLPGVFTLRTLDDADALRAALAPGKRVVVIGGGLIGLEAAAAL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 163 LKAGKKVSIVEVAPLLMRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQINCDSIVYSIGVTPN 242
Cdd:COG1251  162 RKRGLEVTVVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGTGVTEIEGDDRVTGVRLADGEELPADLVVVAIGVRPN 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 243 TKLVHDTAIKLNRGIVVDEKMRTNIDSVYAAGDVAEVNNEIEG-----LWGTALEQGRVAGSNMVSKTAIYKKEIPTTIF 317
Cdd:COG1251  242 TELARAAGLAVDRGIVVDDYLRTSDPDIYAAGDCAEHPGPVYGrrvleLVAPAYEQARVAAANLAGGPAAYEGSVPSTKL 321

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489350042 318 NAFNVSLFSIGVVNKEqcDTTIVEED-GKEKYTRLFIKDNKIVGVISLEGVAASIPYKSAIEKHVSLEGIDLLNTNIS 394
Cdd:COG1251  322 KVFGVDVASAGDAEGD--EEVVVRGDpARGVYKKLVLRDGRLVGAVLVGDTSDAGALRQLIKNGRPLPPRALLDAALP 397
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 6-379 4.37e-72

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 240.50  E-value: 4.37e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042    6 VIIGSGVAAVNAAKTIREYDKGS-NIFIFGEEPLLPYKRIKLSKDLYSDLHSEKVLIKKKKWYQDNHISFFINTKVVKIN 84
Cdd:TIGR02374   2 VLVGNGMAGHRCIEEVLKLNRHMfEITIFGEEPHPNYNRILLSSVLQGEADLDDITLNSKDWYEKHGITLYTGETVIQID 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   85 TDEQFIVTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLEDKESVVTIGGGVQGLETAWSILK 164
Cdd:TIGR02374  82 TDQKQVITDAGRTLSYDKLILATGSYPFILPIPGADKKGVYVFRTIEDLDAIMAMAQRFKKAAVIGGGLLGLEAAVGLQN 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  165 AGKKVSIVEVAPLLMRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQINCDSIVYSIGVTPNTK 244
Cdd:TIGR02374 162 LGMDVSVIHHAPGLMAKQLDQTAGRLLQRELEQKGLTFLLEKDTVEIVGATKADRIRFKDGSSLEADLIVMAAGIRPNDE 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  245 LVHDTAIKLNRGIVVDEKMRTNIDSVYAAGDVAEVNNEIEGLWGTALEQGRVAGSNMV-SKTAIYKKEIPTTIFNAFNVS 323
Cdd:TIGR02374 242 LAVSAGIKVNRGIIVNDSMQTSDPDIYAVGECAEHNGRVYGLVAPLYEQAKVLADHICgVECEEYEGSDLSAKLKLLGVD 321

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489350042  324 LFSIGVVNK-EQCDTTIVEEDGKEKYTRLFIKDNKIVGVI------------SLEGVAASIPYKSAIEK 379
Cdd:TIGR02374 322 VWSAGDAQEtERTTSIKIYDEQKGIYKKLVLSDDKLLGAVlfgdtsdygrllDMVLKQADISEDPAIIK 390
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 6-294 3.25e-55

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 184.44  E-value: 3.25e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042    6 VIIGSGVAAVNAAKTIREYdkGSNIFIFGEEPLLPYKRIKLSKDLYSDLHSEKVLIKKKKWYQD---------NHISFFI 76
Cdd:pfam07992   4 VVIGGGPAGLAAALTLAQL--GGKVTLIEDEGTCPYGGCVLSKALLGAAEAPEIASLWADLYKRkeevvkklnNGIEVLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   77 NTKVVKINTDEQFI-----VTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKgHLEDKESVVTIGG 151
Cdd:pfam07992  82 GTEVVSIDPGAKKVvleelVDGDGETITYDRLVIATGARPRLPPIPGVELNVGFLVRTLDSAEALR-LKLLPKRVVVVGG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  152 GVQGLETAWSILKAGKKVSIVEVAPLLMRrQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQINCD 231
Cdd:pfam07992 161 GYIGVELAAALAKLGKEVTLIEALDRLLR-AFDEEISAALEKALEKNGVEVRLGTSVKEIIGDGDGVEVILKDGTEIDAD 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489350042  232 SIVYSIGVTPNTKLVHDTAIKLNR--GIVVDEKMRTNIDSVYAAGDVAEVnneIEGLWGTALEQG 294
Cdd:pfam07992 240 LVVVAIGRRPNTELLEAAGLELDErgGIVVDEYLRTSVPGIYAAGDCRVG---GPELAQNAVAQG 301
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 2-302 1.13e-46

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 164.71  E-value: 1.13e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   2 EKNFVIIGSGVAAVNAAKTIREYDKGSNIFIFGEEPLLPYKRIKLSKDLYSDLHSEKVLIKKKKWYQDNHISFFINTKVV 81
Cdd:PRK09754   3 EKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYERPPLSKSMLLEDSPQLQQVLPANWWQENNVHLHSGVTIK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  82 KINTDEQFIVTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLEDKESVVTIGGGVQGLETAWS 161
Cdd:PRK09754  83 TLGRDTRELVLTNGESWHWDQLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELAAS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 162 ILKAGKKVSIVEVAPLLMRRQLDTK-SSLLLKRKIEKeGVKVYLNTSIDSILGKESVTgIKMNDNSQINCDSIVYSIGVT 240
Cdd:PRK09754 163 ATQRRCKVTVIELAATVMGRNAPPPvQRYLLQRHQQA-GVRILLNNAIEHVVDGEKVE-LTLQSGETLQADVVIYGIGIS 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489350042 241 PNTKLVHDTAIKLNRGIVVDEKMRTNIDSVYAAGDVA---EVNNEIE--GLWGTALEQGRVAGSNMV 302
Cdd:PRK09754 241 ANDQLAREANLDTANGIVIDEACRTCDPAIFAGGDVAitrLDNGALHrcESWENANNQAQIAAAAML 307
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
3-394 2.98e-128

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 375.25  E-value: 2.98e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   3 KNFVIIGSGVAAVNAAKTIREYDKGSNIFIFGEEPLLPYKRIKLSKDLYSDLHSEKVLIKKKKWYQDNHISFFINTKVVK 82
Cdd:COG1251    2 MRIVIIGAGMAGVRAAEELRKLDPDGEITVIGAEPHPPYNRPPLSKVLAGETDEEDLLLRPADFYEENGIDLRLGTRVTA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  83 INTDEQFIVTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLEDKESVVTIGGGVQGLETAWSI 162
Cdd:COG1251   82 IDRAARTVTLADGETLPYDKLVLATGSRPRVPPIPGADLPGVFTLRTLDDADALRAALAPGKRVVVIGGGLIGLEAAAAL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 163 LKAGKKVSIVEVAPLLMRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQINCDSIVYSIGVTPN 242
Cdd:COG1251  162 RKRGLEVTVVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGTGVTEIEGDDRVTGVRLADGEELPADLVVVAIGVRPN 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 243 TKLVHDTAIKLNRGIVVDEKMRTNIDSVYAAGDVAEVNNEIEG-----LWGTALEQGRVAGSNMVSKTAIYKKEIPTTIF 317
Cdd:COG1251  242 TELARAAGLAVDRGIVVDDYLRTSDPDIYAAGDCAEHPGPVYGrrvleLVAPAYEQARVAAANLAGGPAAYEGSVPSTKL 321

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489350042 318 NAFNVSLFSIGVVNKEqcDTTIVEED-GKEKYTRLFIKDNKIVGVISLEGVAASIPYKSAIEKHVSLEGIDLLNTNIS 394
Cdd:COG1251  322 KVFGVDVASAGDAEGD--EEVVVRGDpARGVYKKLVLRDGRLVGAVLVGDTSDAGALRQLIKNGRPLPPRALLDAALP 397
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 6-379 4.37e-72

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 240.50  E-value: 4.37e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042    6 VIIGSGVAAVNAAKTIREYDKGS-NIFIFGEEPLLPYKRIKLSKDLYSDLHSEKVLIKKKKWYQDNHISFFINTKVVKIN 84
Cdd:TIGR02374   2 VLVGNGMAGHRCIEEVLKLNRHMfEITIFGEEPHPNYNRILLSSVLQGEADLDDITLNSKDWYEKHGITLYTGETVIQID 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   85 TDEQFIVTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLEDKESVVTIGGGVQGLETAWSILK 164
Cdd:TIGR02374  82 TDQKQVITDAGRTLSYDKLILATGSYPFILPIPGADKKGVYVFRTIEDLDAIMAMAQRFKKAAVIGGGLLGLEAAVGLQN 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  165 AGKKVSIVEVAPLLMRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQINCDSIVYSIGVTPNTK 244
Cdd:TIGR02374 162 LGMDVSVIHHAPGLMAKQLDQTAGRLLQRELEQKGLTFLLEKDTVEIVGATKADRIRFKDGSSLEADLIVMAAGIRPNDE 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  245 LVHDTAIKLNRGIVVDEKMRTNIDSVYAAGDVAEVNNEIEGLWGTALEQGRVAGSNMV-SKTAIYKKEIPTTIFNAFNVS 323
Cdd:TIGR02374 242 LAVSAGIKVNRGIIVNDSMQTSDPDIYAVGECAEHNGRVYGLVAPLYEQAKVLADHICgVECEEYEGSDLSAKLKLLGVD 321

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489350042  324 LFSIGVVNK-EQCDTTIVEEDGKEKYTRLFIKDNKIVGVI------------SLEGVAASIPYKSAIEK 379
Cdd:TIGR02374 322 VWSAGDAQEtERTTSIKIYDEQKGIYKKLVLSDDKLLGAVlfgdtsdygrllDMVLKQADISEDPAIIK 390
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 25-328 1.38e-69

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 221.99  E-value: 1.38e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  25 DKGSNIFIFGEEPLLPYKRIKLSKDLYSDLHS-EKVLIKKKKWYQDNHISFFINTKVVKINTDEQFIVTSNEAVFSYHKL 103
Cdd:COG0446    3 GPDAEITVIEKGPHHSYQPCGLPYYVGGGIKDpEDLLVRTPESFERKGIDVRTGTEVTAIDPEAKTVTLRDGETLSYDKL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 104 LICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLEDKE--SVVTIGGGVQGLETAWSILKAGKKVSIVEVAPLLMRR 181
Cdd:COG0446   83 VLATGARPRPPPIPGLDLPGVFTLRTLDDADALREALKEFKgkRAVVIGGGPIGLELAEALRKRGLKVTLVERAPRLLGV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 182 qLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTgIKMNDNSQINCDSIVYSIGVTPNTKLVHDTAIKLNR--GIVV 259
Cdd:COG0446  163 -LDPEMAALLEEELREHGVELRLGETVVAIDGDDKVA-VTLTDGEEIPADLVVVAPGVRPNTELAKDAGLALGErgWIKV 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489350042 260 DEKMRTNIDSVYAAGDVAEVNNEIEG------LWGTALEQGRVAGSNMVSKTAIYkKEIPTTIFNAFNVSLFSIG 328
Cdd:COG0446  241 DETLQTSDPDVYAAGDCAEVPHPVTGktvyipLASAANKQGRVAAENILGGPAPF-PGLGTFISKVFDLCIASTG 314
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 6-294 3.25e-55

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 184.44  E-value: 3.25e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042    6 VIIGSGVAAVNAAKTIREYdkGSNIFIFGEEPLLPYKRIKLSKDLYSDLHSEKVLIKKKKWYQD---------NHISFFI 76
Cdd:pfam07992   4 VVIGGGPAGLAAALTLAQL--GGKVTLIEDEGTCPYGGCVLSKALLGAAEAPEIASLWADLYKRkeevvkklnNGIEVLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   77 NTKVVKINTDEQFI-----VTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKgHLEDKESVVTIGG 151
Cdd:pfam07992  82 GTEVVSIDPGAKKVvleelVDGDGETITYDRLVIATGARPRLPPIPGVELNVGFLVRTLDSAEALR-LKLLPKRVVVVGG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  152 GVQGLETAWSILKAGKKVSIVEVAPLLMRrQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQINCD 231
Cdd:pfam07992 161 GYIGVELAAALAKLGKEVTLIEALDRLLR-AFDEEISAALEKALEKNGVEVRLGTSVKEIIGDGDGVEVILKDGTEIDAD 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489350042  232 SIVYSIGVTPNTKLVHDTAIKLNR--GIVVDEKMRTNIDSVYAAGDVAEVnneIEGLWGTALEQG 294
Cdd:pfam07992 240 LVVVAIGRRPNTELLEAAGLELDErgGIVVDEYLRTSVPGIYAAGDCRVG---GPELAQNAVAQG 301
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 2-302 1.13e-46

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 164.71  E-value: 1.13e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   2 EKNFVIIGSGVAAVNAAKTIREYDKGSNIFIFGEEPLLPYKRIKLSKDLYSDLHSEKVLIKKKKWYQDNHISFFINTKVV 81
Cdd:PRK09754   3 EKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYERPPLSKSMLLEDSPQLQQVLPANWWQENNVHLHSGVTIK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  82 KINTDEQFIVTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLEDKESVVTIGGGVQGLETAWS 161
Cdd:PRK09754  83 TLGRDTRELVLTNGESWHWDQLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELAAS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 162 ILKAGKKVSIVEVAPLLMRRQLDTK-SSLLLKRKIEKeGVKVYLNTSIDSILGKESVTgIKMNDNSQINCDSIVYSIGVT 240
Cdd:PRK09754 163 ATQRRCKVTVIELAATVMGRNAPPPvQRYLLQRHQQA-GVRILLNNAIEHVVDGEKVE-LTLQSGETLQADVVIYGIGIS 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489350042 241 PNTKLVHDTAIKLNRGIVVDEKMRTNIDSVYAAGDVA---EVNNEIE--GLWGTALEQGRVAGSNMV 302
Cdd:PRK09754 241 ANDQLAREANLDTANGIVIDEACRTCDPAIFAGGDVAitrLDNGALHrcESWENANNQAQIAAAAML 307
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 6-355 3.03e-45

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 161.75  E-value: 3.03e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   6 VIIGSGVAAVNAAKTIREYDKGSNIFIFGEEPL-------LPYkrikLSKDLYSDlhSEKVLIKKKKWYQDNHISFFINT 78
Cdd:PRK09564   4 IIIGGTAAGMSAAAKAKRLNKELEITVYEKTDIvsfgacgLPY----FVGGFFDD--PNTMIARTPEEFIKSGIDVKTEH 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  79 KVVKINTDEQFIVTSN---EAVF--SYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLEDKE--SVVTIGG 151
Cdd:PRK09564  78 EVVKVDAKNKTITVKNlktGSIFndTYDKLMIATGARPIIPPIKNINLENVYTLKSMEDGLALKELLKDEEikNIVIIGA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 152 GVQGLETAWSILKAGKKVSIVEVAPLLMRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKmNDNSQINCD 231
Cdd:PRK09564 158 GFIGLEAVEAAKHLGKNVRIIQLEDRILPDSFDKEITDVMEEELRENGVELHLNEFVKSLIGEDKVEGVV-TDKGEYEAD 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 232 SIVYSIGVTPNTKLVHDTAIKL--NRGIVVDEKMRTNIDSVYAAGDVAEVNNEIEG------LWGTALEQGRVAGSNMVS 303
Cdd:PRK09564 237 VVIVATGVKPNTEFLEDTGLKTlkNGAIIVDEYGETSIENIYAAGDCATIYNIVSNknvyvpLATTANKLGRMVGENLAG 316

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489350042 304 KtaiyKKEIPTTIFNAfnvslfSIGVVNKEQCDTTIVEEDGKE---KYTRLFIKD 355
Cdd:PRK09564 317 R----HVSFKGTLGSA------CIKVLDLEAARTGLTEEEAKKlgiDYKTVFIKD 361
PRK14989 PRK14989
nitrite reductase subunit NirD; Provisional
 6-357 1.12e-36

nitrite reductase subunit NirD; Provisional


Pssm-ID: 184951 [Multi-domain]  Cd Length: 847  Bit Score: 142.18  E-value: 1.12e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   6 VIIGSGVAAvnaAKTIREY-DKGS----NIFIFGEEPLLPYKRIKLSKdLYSDLHSEKVLIKKKKWYQDNHISFFINTKV 80
Cdd:PRK14989   7 AIIGNGMVG---HRFIEDLlDKADaanfDITVFCEEPRIAYDRVHLSS-YFSHHTAEELSLVREGFYEKHGIKVLVGERA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  81 VKINTDEQFIVTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLEDKESVVTIGGGVQGLETAW 160
Cdd:PRK14989  83 ITINRQEKVIHSSAGRTVFYDKLIMATGSYPWIPPIKGSETQDCFVYRTIEDLNAIEACARRSKRGAVVGGGLLGLEAAG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 161 SILKAGKKVSIVEVAPLLMRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSIL--GKESVTGIKMNDNSQINCDSIVYSIG 238
Cdd:PRK14989 163 ALKNLGVETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVqeGVEARKTMRFADGSELEVDFIVFSTG 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 239 VTPNTKLVHDTAIKLNR--GIVVDEKMRTNIDSVYAAGDVAEVNNEIEGLWGTALEQGRVAGSNMVSKTAIYKKEIPTTI 316
Cdd:PRK14989 243 IRPQDKLATQCGLAVAPrgGIVINDSCQTSDPDIYAIGECASWNNRVFGLVAPGYKMAQVAVDHLLGSENAFEGADLSAK 322

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 489350042 317 FNAFNVSLFSIGVVN--KEQCDTTIVEEDGKEKYTRLFI-KDNK 357
Cdd:PRK14989 323 LKLLGVDVGGIGDAHgrTPGARSYVYLDESKEIYKRLIVsEDNK 366
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
1-280 1.76e-36

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 136.59  E-value: 1.76e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   1 MEKNFVIIGSGVAAVNAAKTIREYDKGSNIFIF----GEEpllpYKRIKLSKdLYSDLHSEKVLIKKK--KWYQDNHISF 74
Cdd:PRK04965   1 MSNGIVIIGSGFAARQLVKNIRKQDAHIPITLItadsGDE----YNKPDLSH-VFSQGQRADDLTRQSagEFAEQFNLRL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  75 FINTKVVKINTDEQfIVTSNEAVFSYHKLLICTGANNRRLEINGinKKNIFTIRDMKEADELKGHLEDKESVVTIGGGVQ 154
Cdd:PRK04965  76 FPHTWVTDIDAEAQ-VVKSQGNQWQYDKLVLATGASAFVPPIPG--RELMLTLNSQQEYRAAETQLRDAQRVLVVGGGLI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 155 GLETAWSILKAGKKVSIVEVAPLLMRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQINCDSIV 234
Cdd:PRK04965 153 GTELAMDLCRAGKAVTLVDNAASLLASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGIRATLDSGRSIEVDAVI 232

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 489350042 235 YSIGVTPNTKLVHDTAIKLNRGIVVDEKMRTNIDSVYAAGDVAEVN 280
Cdd:PRK04965 233 AAAGLRPNTALARRAGLAVNRGIVVDSYLQTSAPDIYALGDCAEIN 278
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 90-317 6.94e-30

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 119.81  E-value: 6.94e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  90 IVTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLedkesVVtIGGGVQGLETAwSILKA-GKK 168
Cdd:COG1249  121 VEVTGGETLTADHIVIATGSRPRVPPIPGLDEVRVLTSDEALELEELPKSL-----VV-IGGGYIGLEFA-QIFARlGSE 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 169 VSIVEVAPLLMRRqLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNS---QINCDSIVYSIGVTPNTKL 245
Cdd:COG1249  194 VTLVERGDRLLPG-EDPEISEALEKALEKEGIDILTGAKVTSVEKTGDGVTVTLEDGGgeeAVEADKVLVATGRRPNTDG 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 246 VH-DTA-IKLNR--GIVVDEKMRTNIDSVYAAGDVAevnneieglwG------TALEQGRVAGSNMV---SKTAIYKKeI 312
Cdd:COG1249  273 LGlEAAgVELDErgGIKVDEYLRTSVPGIYAIGDVT----------GgpqlahVASAEGRVAAENILgkkPRPVDYRA-I 341


                 ....*
gi 489350042 313 PTTIF 317
Cdd:COG1249  342 PSVVF 346
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
75-277 9.87e-29

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 114.06  E-value: 9.87e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  75 FINTKVVKIN-TDEQFIV-TSNEAVFSYHKLLICTGANNRRLEINGInkkniftirdmkeaDELKGH------------L 140
Cdd:COG0492   74 ILLEEVTSVDkDDGPFRVtTDDGTEYEAKAVIIATGAGPRKLGLPGE--------------EEFEGRgvsycatcdgffF 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 141 EDKEsVVTIGGGVQGLETAWSILKAGKKVSIVevapllMRRQlDTKSSLLLKRKIEK-EGVKVYLNTSIDSILGKESVTG 219
Cdd:COG0492  140 RGKD-VVVVGGGDSALEEALYLTKFASKVTLI------HRRD-ELRASKILVERLRAnPKIEVLWNTEVTEIEGDGRVEG 211

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489350042 220 IKMNDN-----SQINCDSIVYSIGVTPNTKLVHDTAIKLNRG--IVVDEKMRTNIDSVYAAGDVA 277
Cdd:COG0492  212 VTLKNVktgeeKELEVDGVFVAIGLKPNTELLKGLGLELDEDgyIVVDEDMETSVPGVFAAGDVR 276
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
6-300 4.85e-24

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 102.52  E-value: 4.85e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   6 VIIGSGVAAVNAAKTIREYDKG---------SNIFIFGeePLLPY---KRIKLSKDLYsDLhsEKVLikkkkwyQDNHIS 73
Cdd:COG1252    5 VIVGGGFAGLEAARRLRKKLGGdaevtlidpNPYHLFQ--PLLPEvaaGTLSPDDIAI-PL--RELL-------RRAGVR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  74 FfINTKVVKINTDEQFIVTSNEAVFSYHKLLICTGANNRRLEINGInKKNIFTIRDMKEADELKGHLED---------KE 144
Cdd:COG1252   73 F-IQGEVTGIDPEARTVTLADGRTLSYDYLVIATGSVTNFFGIPGL-AEHALPLKTLEDALALRERLLAaferaerrrLL 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 145 SVVTIGGGVQGLETA------------WSILKAGK-KVSIVEVAPLLMRRqLDTKSSLLLKRKIEKEGVKVYLNTSIDSI 211
Cdd:COG1252  151 TIVVVGGGPTGVELAgelaellrkllrYPGIDPDKvRITLVEAGPRILPG-LGEKLSEAAEKELEKRGVEVHTGTRVTEV 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 212 LGkesvTGIKMNDNSQINCDSIVYSIGVTPNtKLVHDTAIKLNRG--IVVDEKMRT-NIDSVYAAGDVAEVNNEIEGLWG 288
Cdd:COG1252  230 DA----DGVTLEDGEEIPADTVIWAAGVKAP-PLLADLGLPTDRRgrVLVDPTLQVpGHPNVFAIGDCAAVPDPDGKPVP 304

                        330
                 ....*....|....*.
gi 489350042 289 ----TALEQGRVAGSN 300
Cdd:COG1252  305 ktaqAAVQQAKVLAKN 320
lipoamide_DH TIGR01350
dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a ...
 75-317 6.39e-22

dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.


Pssm-ID: 273568 [Multi-domain]  Cd Length: 460  Bit Score: 96.94  E-value: 6.39e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   75 FINTKVVKINTdeqfivTSNEAVFSYHKLLICTGANNRrlEINGINKKNIFTIRDMKEADELKghlEDKESVVTIGGGVQ 154
Cdd:TIGR01350 113 FLDPGTVSVTG------ENGEETLEAKNIIIATGSRPR--SLPGPFDFDGKVVITSTGALNLE---EVPESLVIIGGGVI 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  155 GLETAWSILKAGKKVSIVEVAPLLMRrQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQ--INCDS 232
Cdd:TIGR01350 182 GIEFASIFASLGSKVTVIEMLDRILP-GEDAEVSKVLQKALKKKGVKILTNTKVTAVEKNDDQVTYENKGGETetLTGEK 260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  233 IVYSIGVTPNTKL--VHDTAIKLN-RG-IVVDEKMRTNIDSVYAAGDVaevnneIEG--LWGTALEQGRVAGSNMV--SK 304
Cdd:TIGR01350 261 VLVAVGRKPNTEGlgLEKLGVELDeRGrIVVDEYMRTNVPGIYAIGDV------IGGpmLAHVASHEGIVAAENIAgkEP 334

                         250
                  ....*....|...
gi 489350042  305 TAIYKKEIPTTIF 317
Cdd:TIGR01350 335 AHIDYDAVPSVIY 347
TRX_reduct TIGR01292
thioredoxin-disulfide reductase; This model describes thioredoxin-disulfide reductase, a ...
 75-276 1.04e-21

thioredoxin-disulfide reductase; This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport]


Pssm-ID: 273540 [Multi-domain]  Cd Length: 299  Bit Score: 94.23  E-value: 1.04e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   75 FINTKVVKI-NTDEQFIV-TSNEAVFSYHKLLICTGANNRRLEINGINKkniFTIRDMKEADELKGHL-EDKEsVVTIGG 151
Cdd:TIGR01292  73 IIYEEVIKVdKSDRPFKVyTGDGKEYTAKAVIIATGASARKLGIPGEDE---FWGRGVSYCATCDGPFfKNKE-VAVVGG 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  152 GVQGLETAWSILKAGKKVSIVEvapllmRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDN-----S 226
Cdd:TIGR01292 149 GDSAIEEALYLTRIAKKVTLVH------RRDKFRAEKILLDRLKKNPKIEFLWNSTVEEIVGDNKVEGVKIKNTvtgeeE 222

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 489350042  227 QINCDSIVYSIGVTPNTKLVHDtAIKLNRG--IVVDEKMRTNIDSVYAAGDV 276
Cdd:TIGR01292 223 ELEVDGVFIAIGHEPNTELLKG-LLELDENgyIVTDEGMRTSVPGVFAAGDV 273
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 75-317 1.18e-21

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 96.40  E-value: 1.18e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  75 FINTKVVKINtdEQFIVTSNeavfsyhkLLICTGAnnRRLEING---INKKNIFTIRDMKEADELKghledkESVVTIGG 151
Cdd:PRK06292 116 FVDPNTVEVN--GERIEAKN--------IVIATGS--RVPPIPGvwlILGDRLLTSDDAFELDKLP------KSLAVIGG 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 152 GVQGLETA--WSILkaGKKVSIVEVAPLLMRRQlDTKSSLLLKRKIEKEgVKVYLNTSIDSI--LGKESVTGIKMNDNSQ 227
Cdd:PRK06292 178 GVIGLELGqaLSRL--GVKVTVFERGDRILPLE-DPEVSKQAQKILSKE-FKIKLGAKVTSVekSGDEKVEELEKGGKTE 253

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 228 -INCDSIVYSIGVTPNTKLVH--DTAIKL-NRG-IVVDEKMRTNIDSVYAAGDvaeVNNEIEgLWGTALEQGRVAGSNMV 302
Cdd:PRK06292 254 tIEADYVLVATGRRPNTDGLGleNTGIELdERGrPVVDEHTQTSVPGIYAAGD---VNGKPP-LLHEAADEGRIAAENAA 329

                        250
                 ....*....|....*..
gi 489350042 303 SKTAIY--KKEIPTTIF 317
Cdd:PRK06292 330 GDVAGGvrYHPIPSVVF 346
PRK13512 PRK13512
coenzyme A disulfide reductase; Provisional
 6-347 1.61e-19

coenzyme A disulfide reductase; Provisional


Pssm-ID: 184103 [Multi-domain]  Cd Length: 438  Bit Score: 89.84  E-value: 1.61e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   6 VIIGSGVAAVNAAKTIREYDKGSNIFIFGEEPLLPYKRIKLSKDLYSDLHSEK--VLIKKKKWYQDNHISFFINTKVVKI 83
Cdd:PRK13512   5 IVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYYIGEVVEDRKyaLAYTPEKFYDRKQITVKTYHEVIAI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  84 NTDEQFIVTSN---EAVF--SYHKLLICTGANNRRLeinGINKKNIFTIRDMKEADELKGHLE--DKESVVTIGGGVQGL 156
Cdd:PRK13512  85 NDERQTVTVLNrktNEQFeeSYDKLILSPGASANSL---GFESDITFTLRNLEDTDAIDQFIKanQVDKALVVGAGYISL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 157 ETAWSILKAGKKVSIVEVAPLLMRrQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKEsvtgIKMNDNSQINCDSIVYS 236
Cdd:PRK13512 162 EVLENLYERGLHPTLIHRSDKINK-LMDADMNQPILDELDKREIPYRLNEEIDAINGNE----VTFKSGKVEHYDMIIEG 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 237 IGVTPNTKLVHDTAIKLNRG--IVVDEKMRTNIDSVYAAGDVAE-------VNNEIEGLWGTALEQGRVAGSNMVSKTAI 307
Cdd:PRK13512 237 VGTHPNSKFIESSNIKLDDKgfIPVNDKFETNVPNIYAIGDIITshyrhvdLPASVPLAWGAHRAASIVAEQIAGNDTIE 316

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 489350042 308 YKKEIPTTIFNAFNVSLFSIGVVNKE--QCDTTIVEEDGKEK 347
Cdd:PRK13512 317 FKGFLGNNIVKFFDYTFASVGVKPNElkQFDYKMVEVTQGAH 358
PRK06370 PRK06370
FAD-containing oxidoreductase;
91-276 4.91e-19

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 88.72  E-value: 4.91e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  91 VTSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLedkesvVTIGGGVQGLETAWSILKAGKKVS 170
Cdd:PRK06370 125 VRVGGETLRAKRIFINTGARAAIPPIPGLDEVGYLTNETIFSLDELPEHL------VIIGGGYIGLEFAQMFRRFGSEVT 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 171 IVEVAPLLMRRQlDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMN---DNSQINCDSIVYSIGVTPNT-KLV 246
Cdd:PRK06370 199 VIERGPRLLPRE-DEDVAAAVREILEREGIDVRLNAECIRVERDGDGIAVGLDcngGAPEITGSHILVAVGRVPNTdDLG 277

                        170       180       190
                 ....*....|....*....|....*....|...
gi 489350042 247 HDTA-IKLNR--GIVVDEKMRTNIDSVYAAGDV 276
Cdd:PRK06370 278 LEAAgVETDArgYIKVDDQLRTTNPGIYAAGDC 310
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 103-277 1.99e-18

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 86.74  E-value: 1.99e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 103 LLICTGANNRrlEINGIN--KKNIFTIRDMKEADELKghledkESVVTIGGGVQGLE--TAWSILkaGKKVSIVEVAPLL 178
Cdd:PRK06416 138 IILATGSRPR--ELPGIEidGRVIWTSDEALNLDEVP------KSLVVIGGGYIGVEfaSAYASL--GAEVTIVEALPRI 207

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 179 MRRQlDTKSSLLLKRKIEKEGVKVYLNTSIDSIlgKESVTGIKMND-----NSQINCDSIVYSIGVTPNTKLV--HDTAI 251
Cdd:PRK06416 208 LPGE-DKEISKLAERALKKRGIKIKTGAKAKKV--EQTDDGVTVTLedggkEETLEADYVLVAVGRRPNTENLglEELGV 284

                        170       180
                 ....*....|....*....|....*..
gi 489350042 252 KLNRG-IVVDEKMRTNIDSVYAAGDVA 277
Cdd:PRK06416 285 KTDRGfIEVDEQLRTNVPNIYAIGDIV 311
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
6-317 2.24e-18

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 86.36  E-value: 2.24e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   6 VIIGSGV----AAVNAA---------------------------KTIREydKGSNIFIFGEEPLlpYKRIKLSKDL-YSD 53
Cdd:PRK05249   9 VVIGSGPagegAAMQAAklgkrvavieryrnvgggcthtgtipsKALRE--AVLRLIGFNQNPL--YSSYRVKLRItFAD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  54 L--HSEKVLIK----KKKWYQDNHISFFI--------NTKVVKINTDEQFIVTSNeavfsyhKLLICTGANNRRLEINGI 119
Cdd:PRK05249  85 LlaRADHVINKqvevRRGQYERNRVDLIQgrarfvdpHTVEVECPDGEVETLTAD-------KIVIATGSRPYRPPDVDF 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 120 NKKNIF---TIRDMKEadelkghleDKESVVTIGGGVQGLETAwSILKA-GKKVSIVEvapllmRRQ-----LDTKSSLL 190
Cdd:PRK05249 158 DHPRIYdsdSILSLDH---------LPRSLIIYGAGVIGCEYA-SIFAAlGVKVTLIN------TRDrllsfLDDEISDA 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 191 LKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQINCDSIVYSIGVTPNTKLVHDTAIKL---NRG-IVVDEKMRTN 266
Cdd:PRK05249 222 LSYHLRDSGVTIRHNEEVEKVEGGDDGVIVHLKSGKKIKADCLLYANGRTGNTDGLNLENAGLeadSRGqLKVNENYQTA 301

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 489350042 267 IDSVYAAGDVaevnneI--EGLWGTALEQGRVAGSNMV-SKTAIYKKEIPTTIF 317
Cdd:PRK05249 302 VPHIYAVGDV------IgfPSLASASMDQGRIAAQHAVgEATAHLIEDIPTGIY 349
MerA TIGR02053
mercury(II) reductase; This model represents the mercuric reductase found in the mer operon ...
 75-361 5.59e-17

mercury(II) reductase; This model represents the mercuric reductase found in the mer operon for the detoxification of mercury compounds. MerA is a FAD-containing flavoprotein which reduces Hg(II) to Hg(0) utilizing NADPH. [Cellular processes, Detoxification]


Pssm-ID: 273944 [Multi-domain]  Cd Length: 463  Bit Score: 82.47  E-value: 5.59e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   75 FINTKVVKINtdeqfivtSNEAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKghledkESVVTIGGGVQ 154
Cdd:TIGR02053 112 FKDPKTVKVD--------LGREVRGAKRFLIATGARPAIPPIPGLKEAGYLTSEEALALDRIP------ESLAVIGGGAI 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  155 GLETAWSILKAGKKVSIVEVAPLLMRRQlDTKSSLLLKRKIEKEGVKVYLNTSIDSI---LGKESVTGIKMNDNSQINCD 231
Cdd:TIGR02053 178 GVELAQAFARLGSEVTILQRSDRLLPRE-EPEISAAVEEALAEEGIEVVTSAQVKAVsvrGGGKIITVEKPGGQGEVEAD 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  232 SIVYSIGVTPNTKLVH--DTAIKLNR--GIVVDEKMRTNIDSVYAAGDVAEvNNEIEGLwgtALEQGRVAGSNMV--SKT 305
Cdd:TIGR02053 257 ELLVATGRRPNTDGLGleKAGVKLDErgGILVDETLRTSNPGIYAAGDVTG-GLQLEYV---AAKEGVVAAENALggANA 332

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489350042  306 AIYKKEIPTTIFNAFNVSlfSIGVVNKE------QCDTTIVEEDGKEK-----YTRLFIKDN------KIVGV 361
Cdd:TIGR02053 333 KLDLLVIPRVVFTDPAVA--SVGLTEAEaqkagiECDCRTLPLTNVPRarinrDTRGFIKLVaepgtgKVLGV 403
PRK07251 PRK07251
FAD-containing oxidoreductase;
75-333 8.47e-15

FAD-containing oxidoreductase;


Pssm-ID: 180907 [Multi-domain]  Cd Length: 438  Bit Score: 75.56  E-value: 8.47e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  75 FINTKVVKINTDEQFIVTSNEAVfsyhklLICTGANNRRLEINGI-NKKNIFTIRDMKEADELKGHLEdkesvvTIGGGV 153
Cdd:PRK07251 100 FVSNKVIEVQAGDEKIELTAETI------VINTGAVSNVLPIPGLaDSKHVYDSTGIQSLETLPERLG------IIGGGN 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 154 QGLETAWSILKAGKKVSIVEVAPLLMRRQLDTKSSLLlKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQInCDSI 233
Cdd:PRK07251 168 IGLEFAGLYNKLGSKVTVLDAASTILPREEPSVAALA-KQYMEEDGITFLLNAHTTEVKNDGDQVLVVTEDETYR-FDAL 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 234 VYSIGVTPNTKLVH--DTAIKLN-RG-IVVDEKMRTNIDSVYAAGDvaeVNNEIEGLWgTALEQGRVAGSNMV---SKTA 306
Cdd:PRK07251 246 LYATGRKPNTEPLGleNTDIELTeRGaIKVDDYCQTSVPGVFAVGD---VNGGPQFTY-ISLDDFRIVFGYLTgdgSYTL 321

                        250       260
                 ....*....|....*....|....*..
gi 489350042 307 IYKKEIPTTIFnaFNVSLFSIGVVNKE 333
Cdd:PRK07251 322 EDRGNVPTTMF--ITPPLSQVGLTEKE 346
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
 72-297 4.39e-13

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 70.02  E-value: 4.39e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  72 ISFFINTKVV------KINTDE--QFIVTSNEAVFSYHKLLICTGA-NNRRLEINGINKKNI-------FTIRDMKeade 135
Cdd:PRK12770  83 VVFHTRTKVCcgeplhEEEGDEfvERIVSLEELVKKYDAVLIATGTwKSRKLGIPGEDLPGVysaleylFRIRAAK---- 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 136 lKGHLeDKES--------VVTIGGGVQGLETAWSILKAGkkvsiVEVAPLLMRRQLD----TKSSLllkRKIEKEGVKVY 203
Cdd:PRK12770 159 -LGYL-PWEKvppvegkkVVVVGAGLTAVDAALEAVLLG-----AEKVYLAYRRTINeapaGKYEI---ERLIARGVEFL 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 204 LNTSIDSILGKESVTGIKM--------------------NDNSQINCDSIVYSIGVTPNTKL-VHDTAIKLNRG--IVVD 260
Cdd:PRK12770 229 ELVTPVRIIGEGRVEGVELakmrlgepdesgrprpvpipGSEFVLEADTVVFAIGEIPTPPFaKECLGIELNRKgeIVVD 308

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 489350042 261 EKMRTNIDSVYAAGDVAEVNNEIeglwGTALEQGRVA 297
Cdd:PRK12770 309 EKHMTSREGVFAAGDVVTGPSKI----GKAIKSGLRA 341
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 75-281 4.75e-13

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 70.18  E-value: 4.75e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  75 FINTKVVKINTDEQFI----------VTSNEAVFSYHKLLICTGANNRRLEINGInKKNIFTIRDMKEADELKGHL---- 140
Cdd:PTZ00318  79 YLRAVVYDVDFEEKRVkcgvvsksnnANVNTFSVPYDKLVVAHGARPNTFNIPGV-EERAFFLKEVNHARGIRKRIvqci 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 141 ----------EDKE---SVVTIGGGVQGLETAWSI--------------LKAGKKVSIVEVAPLLMRrQLDTKSSLLLKR 193
Cdd:PTZ00318 158 eraslpttsvEERKrllHFVVVGGGPTGVEFAAELadffrddvrnlnpeLVEECKVTVLEAGSEVLG-SFDQALRKYGQR 236

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 194 KIEKEGVKVYLNTSIDSILGKESVTgikmNDNSQINCDSIVYSIGVTPNTKLVHDTAIKLNRG-IVVDEKMRT-NIDSVY 271
Cdd:PTZ00318 237 RLRRLGVDIRTKTAVKEVLDKEVVL----KDGEVIPTGLVVWSTGVGPGPLTKQLKVDKTSRGrISVDDHLRVkPIPNVF 312

                        250
                 ....*....|
gi 489350042 272 AAGDVAEVNN 281
Cdd:PTZ00318 313 ALGDCAANEE 322
PRK08010 PRK08010
pyridine nucleotide-disulfide oxidoreductase; Provisional
 75-276 1.36e-12

pyridine nucleotide-disulfide oxidoreductase; Provisional


Pssm-ID: 181196 [Multi-domain]  Cd Length: 441  Bit Score: 68.89  E-value: 1.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  75 FINTKVVKINTDEQFIVTSNEAVFsyhkllICTGANNRRLEINGINKK-NIFTIRDMKEADELKGHLEdkesvvTIGGGV 153
Cdd:PRK08010 101 FINNHSLRVHRPEGNLEIHGEKIF------INTGAQTVVPPIPGITTTpGVYDSTGLLNLKELPGHLG------ILGGGY 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 154 QGLETAWSILKAGKKVSIVEVAPLLMRRQlDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKmNDNSQINCDSI 233
Cdd:PRK08010 169 IGVEFASMFANFGSKVTILEAASLFLPRE-DRDIADNIATILRDQGVDIILNAHVERISHHENQVQVH-SEHAQLAVDAL 246

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 489350042 234 VYSIGVTPNTKLVH--DTAIKLNR--GIVVDEKMRTNIDSVYAAGDV 276
Cdd:PRK08010 247 LIASGRQPATASLHpeNAGIAVNErgAIVVDKYLHTTADNIWAMGDV 293
PRK06327 PRK06327
dihydrolipoamide dehydrogenase; Validated
 60-317 3.42e-12

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235779 [Multi-domain]  Cd Length: 475  Bit Score: 67.64  E-value: 3.42e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  60 LIKKkkwyqdNHISFFINTKVVKINTDEQFIV----TSNEAVFSYHkLLICTGANNRRLEINGINKKNIFTIRDMKEADE 135
Cdd:PRK06327 109 LFKK------NKITVLKGRGSFVGKTDAGYEIkvtgEDETVITAKH-VIIATGSEPRHLPGVPFDNKIILDNTGALNFTE 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 136 LKGHLedkesvVTIGGGVQGLETA--WSILkaGKKVSIVEVAPLLMRRQLDTKSSLLLKrKIEKEGVKVYLNTSIDSI-L 212
Cdd:PRK06327 182 VPKKL------AVIGAGVIGLELGsvWRRL--GAEVTILEALPAFLAAADEQVAKEAAK-AFTKQGLDIHLGVKIGEIkT 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 213 GKESVTgIKMND---NSQ-INCDSIVYSIGVTPNTK-LVHDTA-IKLN-RG-IVVDEKMRTNIDSVYAAGDVaevnneIE 284
Cdd:PRK06327 253 GGKGVS-VAYTDadgEAQtLEVDKLIVSIGRVPNTDgLGLEAVgLKLDeRGfIPVDDHCRTNVPNVYAIGDV------VR 325

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 489350042 285 G--LWGTALEQGRVAGSNMVSKTA-IYKKEIPTTIF 317
Cdd:PRK06327 326 GpmLAHKAEEEGVAVAERIAGQKGhIDYNTIPWVIY 361
Rubredoxin_C pfam18267
Rubredoxin NAD+ reductase C-terminal domain; This is the C-terminal domain of NADH rubredoxin ...
 313-379 1.21e-11

Rubredoxin NAD+ reductase C-terminal domain; This is the C-terminal domain of NADH rubredoxin oxidoreductase present in Clostridium acetobutylicum. The majority of obligatory anaerobes detoxify micro-aerobic environments by consuming O2 via H2O-forming NADH oxidase. This enzyme offers an alternate reaction pathway for scavenging of O2 and reactive oxygen species, wherein the reducing equivalent is obtained from NADH.


Pssm-ID: 408082 [Multi-domain]  Cd Length: 70  Bit Score: 59.88  E-value: 1.21e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489350042  313 PTTIFNAFNVSLFSIGVVNK-EQCDTTIVEEDGKEKYTRLFIKDNKIVGVISLEGVAASIPYKSAIEK 379
Cdd:pfam18267   1 PSTILKVFGIDLFSMGDIEEnDNAEEIVKVDASNGIYKKLFIRDGKLVGAILIGDTSESPKLKKAIEK 68
PRK06116 PRK06116
glutathione reductase; Validated
 102-354 1.45e-11

glutathione reductase; Validated


Pssm-ID: 235701 [Multi-domain]  Cd Length: 450  Bit Score: 65.56  E-value: 1.45e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 102 KLLICTGANNRRLEINGINkkniFTIrDMKEADELKghlEDKESVVTIGGGVQGLETAwSILKA-GKKVSivevapLLMR 180
Cdd:PRK06116 134 HILIATGGRPSIPDIPGAE----YGI-TSDGFFALE---ELPKRVAVVGAGYIAVEFA-GVLNGlGSETH------LFVR 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 181 RQL-----DTKSSLLLKRKIEKEGVKVYLNTSIDSI--LGKESVTgIKMNDNSQINCDSIVYSIGVTPNTKLV--HDTAI 251
Cdd:PRK06116 199 GDAplrgfDPDIRETLVEEMEKKGIRLHTNAVPKAVekNADGSLT-LTLEDGETLTVDCLIWAIGREPNTDGLglENAGV 277

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 252 KLN-RG-IVVDEKMRTNIDSVYAAGDvaeVNNEIEgLWGTALEQGRVagsnmVSKTAIYKKE--------IPTTIFnafn 321
Cdd:PRK06116 278 KLNeKGyIIVDEYQNTNVPGIYAVGD---VTGRVE-LTPVAIAAGRR-----LSERLFNNKPdekldysnIPTVVF---- 344

                        250       260       270
                 ....*....|....*....|....*....|...
gi 489350042 322 vSLFSIGVVNkeqcdttIVEEDGKEKYTRLFIK 354
Cdd:PRK06116 345 -SHPPIGTVG-------LTEEEAREQYGEDNVK 369
PRK15317 PRK15317
alkyl hydroperoxide reductase subunit F; Provisional
 146-279 4.94e-11

alkyl hydroperoxide reductase subunit F; Provisional


Pssm-ID: 237942 [Multi-domain]  Cd Length: 517  Bit Score: 64.02  E-value: 4.94e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 146 VVTIGGGVQGLETAwsILKAG--KKVSIVEVAPLLmrrqldtKSSLLLKRKIEK-EGVKVYLNTSIDSILGKES-VTGIK 221
Cdd:PRK15317 354 VAVIGGGNSGVEAA--IDLAGivKHVTVLEFAPEL-------KADQVLQDKLRSlPNVTIITNAQTTEVTGDGDkVTGLT 424

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489350042 222 MNDNS-----QINCDSIVYSIGVTPNTKLVHDTaIKLN-RG-IVVDEKMRTNIDSVYAAGDVAEV 279
Cdd:PRK15317 425 YKDRTtgeehHLELEGVFVQIGLVPNTEWLKGT-VELNrRGeIIVDARGATSVPGVFAAGDCTTV 488
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 145-224 7.58e-11

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 57.98  E-value: 7.58e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  145 SVVTIGGGVQGLETAWSILKAGKKVSIVEVAPLLMrRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMND 224
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGSKVTVVERRDRLL-PGFDPEIAKILQEKLEKNGIEFLLNTTVEAIEGNGDGVVVVLTD 79
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 72-277 9.57e-11

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 63.23  E-value: 9.57e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  72 ISFFINTKVVK-INTDE---QFivtsnEAVFsyhkllICTGA-NNRRLEINGINKKNIFT----IRDMKEADELKGHLED 142
Cdd:COG0493  186 VEFRTNVEVGKdITLDElleEF-----DAVF------LATGAgKPRDLGIPGEDLKGVHSamdfLTAVNLGEAPDTILAV 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 143 KESVVTIGGGVQGLETAWSILKAG-KKVSIVEvapllMRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKES--VTG 219
Cdd:COG0493  255 GKRVVVIGGGNTAMDCARTALRLGaESVTIVY-----RRTREEMPASKEEVEEALEEGVEFLFLVAPVEIIGDENgrVTG 329

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 220 IKM-------NDNS-------------QINCDSIVYSIGVTPNTKLVHDTA-IKLNRG--IVVDEK-MRTNIDSVYAAGD 275
Cdd:COG0493  330 LECvrmelgePDESgrrrpvpiegsefTLPADLVILAIGQTPDPSGLEEELgLELDKRgtIVVDEEtYQTSLPGVFAGGD 409


                 ..
gi 489350042 276 VA 277
Cdd:COG0493  410 AV 411
PRK13748 PRK13748
putative mercuric reductase; Provisional
 95-275 1.10e-10

putative mercuric reductase; Provisional


Pssm-ID: 184298 [Multi-domain]  Cd Length: 561  Bit Score: 63.25  E-value: 1.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  95 EAVFSYHKLLICTGANNRRLEINGINKKNIFTIRDMKEADELKGHLedkesvVTIGGGVQGLETAWSILKAGKKVSIVEV 174
Cdd:PRK13748 228 ERVVAFDRCLIATGASPAVPPIPGLKETPYWTSTEALVSDTIPERL------AVIGSSVVALELAQAFARLGSKVTILAR 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 175 APLLMRRqlDTKSSLLLKRKIEKEGVKVYLNTSIDSI--LGKESV--TGikmndNSQINCDSIVYSIGVTPNT-KLVHDT 249
Cdd:PRK13748 302 STLFFRE--DPAIGEAVTAAFRAEGIEVLEHTQASQVahVDGEFVltTG-----HGELRADKLLVATGRAPNTrSLALDA 374

                        170       180
                 ....*....|....*....|....*....
gi 489350042 250 A-IKLN-RG-IVVDEKMRTNIDSVYAAGD 275
Cdd:PRK13748 375 AgVTVNaQGaIVIDQGMRTSVPHIYAAGD 403
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 96-277 7.26e-10

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 60.58  E-value: 7.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  96 AVFsyhkllICTGANN-RRLEINGINKKNIF-------TIRDMKEADEL-KGhledkESVVTIGGGvqglETAW-----S 161
Cdd:PRK11749 228 AVF------IGTGAGLpRFLGIPGENLGGVYsavdfltRVNQAVADYDLpVG-----KRVVVIGGG----NTAMdaartA 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 162 ILKAGKKVSIVevapllMRRQLD--TKSslllKRKIE---KEGVKVYLNTSIDSILGKE----SVTGIKMNDNSQ----- 227
Cdd:PRK11749 293 KRLGAESVTIV------YRRGREemPAS----EEEVEhakEEGVEFEWLAAPVEILGDEgrvtGVEFVRMELGEPdasgr 362

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489350042 228 -----------INCDSIVYSIGVTPNTKLVHDT-AIKLNR--GIVVDEK-MRTNIDSVYAAGDVA 277
Cdd:PRK11749 363 rrvpiegseftLPADLVIKAIGQTPNPLILSTTpGLELNRwgTIIADDEtGRTSLPGVFAGGDIV 427
PRK07846 PRK07846
mycothione reductase; Reviewed
 144-276 7.53e-10

mycothione reductase; Reviewed


Pssm-ID: 181142 [Multi-domain]  Cd Length: 451  Bit Score: 60.35  E-value: 7.53e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 144 ESVVTIGGGVQGLETAWSILKAGKKVSIVEVAPLLMRRQLDTKSSLLLKrkIEKEGVKVYLNTSIDSILGKESVTGIKMN 223
Cdd:PRK07846 167 ESLVIVGGGFIAAEFAHVFSALGVRVTVVNRSGRLLRHLDDDISERFTE--LASKRWDVRLGRNVVGVSQDGSGVTLRLD 244

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489350042 224 DNSQINCDSIVYSIGVTPNTKL--VHDTAIKLNRG--IVVDEKMRTNIDSVYAAGDV 276
Cdd:PRK07846 245 DGSTVEADVLLVATGRVPNGDLldAAAAGVDVDEDgrVVVDEYQRTSAEGVFALGDV 301
PLN02507 PLN02507
glutathione reductase
 79-276 3.14e-09

glutathione reductase


Pssm-ID: 215281 [Multi-domain]  Cd Length: 499  Bit Score: 58.67  E-value: 3.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  79 KVVKINTDEQFIVTSNEAVFSYHKLLICTGANNRRLEINGinkKNIFTIRDmkEADELKghlEDKESVVTIGGGVQGLET 158
Cdd:PLN02507 147 KIVGPNEVEVTQLDGTKLRYTAKHILIATGSRAQRPNIPG---KELAITSD--EALSLE---ELPKRAVVLGGGYIAVEF 218

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 159 AwSILKA-GKKVSIVEVAPLLMRrQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESVTGIKMNDNSQINCDSIVYSI 237
Cdd:PLN02507 219 A-SIWRGmGATVDLFFRKELPLR-GFDDEMRAVVARNLEGRGINLHPRTNLTQLTKTEGGIKVITDHGEEFVADVVLFAT 296

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 489350042 238 GVTPNTKLVH--DTAIKLNR--GIVVDEKMRTNIDSVYAAGDV 276
Cdd:PLN02507 297 GRAPNTKRLNleAVGVELDKagAVKVDEYSRTNIPSIWAIGDV 339
TGR TIGR01438
thioredoxin and glutathione reductase selenoprotein; This homodimeric, FAD-containing member ...
 58-317 2.01e-08

thioredoxin and glutathione reductase selenoprotein; This homodimeric, FAD-containing member of the pyridine nucleotide disulfide oxidoreductase family contains a C-terminal motif Cys-SeCys-Gly, where SeCys is selenocysteine encoded by TGA (in some sequence reports interpreted as a stop codon). In some members of this subfamily, Cys-SeCys-Gly is replaced by Cys-Cys-Gly. The reach of the selenium atom at the C-term arm of the protein is proposed to allow broad substrate specificity.


Pssm-ID: 273624 [Multi-domain]  Cd Length: 484  Bit Score: 56.01  E-value: 2.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   58 KVLIKKKKWYQDNHISFFINTKVVKiNTDEQfivtSNEAVFSYHKLLICTGANNRRLEINGINKKNIftirdmkEADELK 137
Cdd:TIGR01438 107 RVALREKKVKYENAYAEFVDKHRIK-ATNKK----GKEKIYSAERFLIATGERPRYPGIPGAKELCI-------TSDDLF 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  138 GHLEDKESVVTIGGGVQGLETAWSILKAGKKVSIVEVAPLLmrRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKESV 217
Cdd:TIGR01438 175 SLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILL--RGFDQDCANKVGEHMEEHGVKFKRQFVPIKVEQIEAK 252

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  218 TGIKMNDNSQINC---DSIVYSIGVTPNTKLVH--DTAIKLNRG---IVVDEKMRTNIDSVYAAGDVAEVNNEIEGLwgt 289
Cdd:TIGR01438 253 VLVEFTDSTNGIEeeyDTVLLAIGRDACTRKLNleNVGVKINKKtgkIPADEEEQTNVPYIYAVGDILEDKPELTPV--- 329

                         250       260       270
                  ....*....|....*....|....*....|
gi 489350042  290 ALEQGRVAGSNMV--SKTAIYKKEIPTTIF 317
Cdd:TIGR01438 330 AIQAGRLLAQRLFkgSTVICDYENVPTTVF 359
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
70-274 2.40e-08

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 54.92  E-value: 2.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042   70 NHISFFINTKVVKIN-TDEQFIVTSNEAVFSYHKLLICTG--ANNRRLEINGINKKNiftiRDMKEADELKGhledkESV 146
Cdd:pfam13738  88 FELPINLFEEVTSVKkEDDGFVVTTSKGTYQARYVIIATGefDFPNKLGVPELPKHY----SYVKDFHPYAG-----QKV 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  147 VTIGGGVQGLETAWSILKAGKKVSIVEVAPLLMRRQLDTKSSL------LLKRKIEKEGVKVYLNTSIDSILGKESVTGI 220
Cdd:pfam13738 159 VVIGGYNSAVDAALELVRKGARVTVLYRGSEWEDRDSDPSYSLspdtlnRLEELVKNGKIKAHFNAEVKEITEVDVSYKV 238

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 489350042  221 KMNDNSQINCDSI-VYSIGVTPNTKLVHDTAIKLNR-GIVV--DEKMRTNIDSVYAAG 274
Cdd:pfam13738 239 HTEDGRKVTSNDDpILATGYHPDLSFLKKGLFELDEdGRPVltEETESTNVPGLFLAG 296
PRK07845 PRK07845
flavoprotein disulfide reductase; Reviewed
 104-297 9.86e-07

flavoprotein disulfide reductase; Reviewed


Pssm-ID: 236112 [Multi-domain]  Cd Length: 466  Bit Score: 50.63  E-value: 9.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 104 LICTGANNRRL---EINGinkKNIFTIRDMKEADELKGHLedkesvVTIGGGVQGLETAWSILKAGKKVSIV----EVAP 176
Cdd:PRK07845 144 LIATGASPRILptaEPDG---ERILTWRQLYDLDELPEHL------IVVGSGVTGAEFASAYTELGVKVTLVssrdRVLP 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 177 llmrrQLDTKSSLLLKRKIEKEGVKVYLNTSIDSIlgkeSVTG----IKMNDNSQINCDSIVYSIGVTPNTK-LVHDTA- 250
Cdd:PRK07845 215 -----GEDADAAEVLEEVFARRGMTVLKRSRAESV----ERTGdgvvVTLTDGRTVEGSHALMAVGSVPNTAgLGLEEAg 285

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 489350042 251 IKLNRG--IVVDEKMRTNIDSVYAAGDVAEVNneieGLWGTALEQGRVA 297
Cdd:PRK07845 286 VELTPSghITVDRVSRTSVPGIYAAGDCTGVL----PLASVAAMQGRIA 330
PRK12831 PRK12831
putative oxidoreductase; Provisional
 76-275 5.95e-06

putative oxidoreductase; Provisional


Pssm-ID: 183780 [Multi-domain]  Cd Length: 464  Bit Score: 48.09  E-value: 5.95e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  76 INTKVV---KINTDEQFIVTSNEAVFsyhkllICTGANNRR-LEINGINKKNIFTirdmkeADE-------LKGHLEDKE 144
Cdd:PRK12831 208 IETNVVvgkTVTIDELLEEEGFDAVF------IGSGAGLPKfMGIPGENLNGVFS------ANEfltrvnlMKAYKPEYD 275

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 145 S-------VVTIGGGVQGLETAWSILKAGKKVSIVevapllMRRqldTKSSLLLKRK----IEKEGVKVYLNTSIDSILG 213
Cdd:PRK12831 276 TpikvgkkVAVVGGGNVAMDAARTALRLGAEVHIV------YRR---SEEELPARVEevhhAKEEGVIFDLLTNPVEILG 346

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 214 KES--VTG---IKMN----DNS-------------QINCDSIVYSIGVTPNtKLVHDTA--IKLNRG--IVVDEKM-RTN 266
Cdd:PRK12831 347 DENgwVKGmkcIKMElgepDASgrrrpveiegsefVLEVDTVIMSLGTSPN-PLISSTTkgLKINKRgcIVADEETgLTS 425


                 ....*....
gi 489350042 267 IDSVYAAGD 275
Cdd:PRK12831 426 KEGVFAGGD 434
PRK12778 PRK12778
bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate ...
 117-276 7.19e-06

bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate synthase;


Pssm-ID: 237200 [Multi-domain]  Cd Length: 752  Bit Score: 48.20  E-value: 7.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 117 NGINKKNIFTIRD--MKEADEL-KGHLEDKESVVTIGGGVQGLETAWSILKAGkkvsiVEVAPLLMRRQLDTKSSLLLKR 193
Cdd:PRK12778 541 NGVMSSNEYLTRVnlMDAASPDsDTPIKFGKKVAVVGGGNTAMDSARTAKRLG-----AERVTIVYRRSEEEMPARLEEV 615

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 194 K-IEKEGVKVYLNTSIDSILGKE-----SVTGIKMN----DNS-------------QINCDSIVYSIGVTPNtKLVHDT- 249
Cdd:PRK12778 616 KhAKEEGIEFLTLHNPIEYLADEkgwvkQVVLQKMElgepDASgrrrpvaipgstfTVDVDLVIVSVGVSPN-PLVPSSi 694

                        170       180       190
                 ....*....|....*....|....*....|
gi 489350042 250 -AIKLNR--GIVVDEKMRTNIDSVYAAGDV 276
Cdd:PRK12778 695 pGLELNRkgTIVVDEEMQSSIPGIYAGGDI 724
PTZ00052 PTZ00052
thioredoxin reductase; Provisional
 149-317 3.02e-05

thioredoxin reductase; Provisional


Pssm-ID: 185416 [Multi-domain]  Cd Length: 499  Bit Score: 45.97  E-value: 3.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 149 IGGGVQGLETAWSILKAGKKVSI-VEVAPLlmrRQLDTKSSLLLKRKIEKEGVKvYLNTSIDSILGK-ESVTGIKMNDNS 226
Cdd:PTZ00052 188 VGASYIGLETAGFLNELGFDVTVaVRSIPL---RGFDRQCSEKVVEYMKEQGTL-FLEGVVPINIEKmDDKIKVLFSDGT 263

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 227 QINCDSIVYSIGVTPNTKLVHDTAIKL-----NRGIVVDEKmrTNIDSVYAAGDVAEVNNEiegLWGTALEQGRVAGSNM 301
Cdd:PTZ00052 264 TELFDTVLYATGRKPDIKGLNLNAIGVhvnksNKIIAPNDC--TNIPNIFAVGDVVEGRPE---LTPVAIKAGILLARRL 338

                        170
                 ....*....|....*...
gi 489350042 302 V--SKTAIYKKEIPTTIF 317
Cdd:PTZ00052 339 FkqSNEFIDYTFIPTTIF 356
PTZ00058 PTZ00058
glutathione reductase; Provisional
 140-286 5.28e-05

glutathione reductase; Provisional


Pssm-ID: 185420 [Multi-domain]  Cd Length: 561  Bit Score: 45.38  E-value: 5.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 140 LEDKESVVTIGGGVQGLETAwSILKAGKKVSIVEVAPLLMRRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSILGKES--V 217
Cdd:PTZ00058 234 IKEAKRIGIAGSGYIAVELI-NVVNRLGAESYIFARGNRLLRKFDETIINELENDMKKNNINIITHANVEEIEKVKEknL 312

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489350042 218 TGIKMNDNSQINCDSIVYSIGVTPNTKLVHDTAI--KLNRG-IVVDEKMRTNIDSVYAAGDVAEV--NNEIEGL 286
Cdd:PTZ00058 313 TIYLSDGRKYEHFDYVIYCVGRSPNTEDLNLKALniKTPKGyIKVDDNQRTSVKHIYAVGDCCMVkkNQEIEDL 386
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
145-241 8.99e-05

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 44.47  E-value: 8.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 145 SVVTIGGGVQGLETAWSILKAGKKVSIVEVAPLL--MRRQLDTK------SSLLLKRKIEK----EGVKVYLNTSIDSIL 212
Cdd:COG1148  142 RALVIGGGIAGMTAALELAEQGYEVYLVEKEPELggRAAQLHKTfpgldcPQCILEPLIAEveanPNITVYTGAEVEEVS 221

                         90       100       110
                 ....*....|....*....|....*....|....
gi 489350042 213 GKE---SVTgIKMNDNS--QINCDSIVYSIGVTP 241
Cdd:COG1148  222 GYVgnfTVT-IKKGPREeiEIEVGAIVLATGFKP 254
trypano_reduc TIGR01423
trypanothione-disulfide reductase; Trypanothione, a glutathione-modified derivative of ...
 141-278 9.91e-05

trypanothione-disulfide reductase; Trypanothione, a glutathione-modified derivative of spermidine, is (in its reduced form) an important antioxidant found in trypanosomatids (Crithidia, Leishmania, Trypanosoma). This model describes trypanothione reductase, a possible antitrypanosomal drug target closely related to some forms of glutathione reductase.


Pssm-ID: 200098 [Multi-domain]  Cd Length: 486  Bit Score: 44.19  E-value: 9.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042  141 EDKESVVTIGGGVQGLETAwSILKA----GKKVSIVEVAPLLMRrQLDTKSSLLLKRKIEKEGVKVYLNTSIDSI-LGKE 215
Cdd:TIGR01423 185 EPPRRVLTVGGGFISVEFA-GIFNAykprGGKVTLCYRNNMILR-GFDSTLRKELTKQLRANGINIMTNENPAKVtLNAD 262

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489350042  216 SVTGIKMNDNSQINCDSIVYSIGVTPNTKLVH--DTAIKL--NRGIVVDEKMRTNIDSVYAAGDVAE 278
Cdd:TIGR01423 263 GSKHVTFESGKTLDVDVVMMAIGRVPRTQTLQldKVGVELtkKGAIQVDEFSRTNVPNIYAIGDVTD 329
PLN02546 PLN02546
glutathione reductase
 144-278 2.94e-04

glutathione reductase


Pssm-ID: 215301 [Multi-domain]  Cd Length: 558  Bit Score: 42.94  E-value: 2.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489350042 144 ESVVTIGGGVQGLETA--WSILKAGKKVSIVEVAPLlmrRQLDTKSSLLLKRKIEKEGVKVYLNTSIDSIL-GKESVTGI 220
Cdd:PLN02546 253 EKIAIVGGGYIALEFAgiFNGLKSDVHVFIRQKKVL---RGFDEEVRDFVAEQMSLRGIEFHTEESPQAIIkSADGSLSL 329

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489350042 221 KMNDNSQINCDSIVYSIGVTPNTKLV--HDTAIKLNR--GIVVDEKMRTNIDSVYAAGDVAE 278
Cdd:PLN02546 330 KTNKGTVEGFSHVMFATGRKPNTKNLglEEVGVKMDKngAIEVDEYSRTSVPSIWAVGDVTD 391
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH