|
Name |
Accession |
Description |
Interval |
E-value |
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
180-523 |
1.37e-69 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 229.08 E-value: 1.37e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 180 TETLAEERAEtVANLEELNALILQRMRTGILVVDSRQAILLANQAALGLLRQD--DVQGASLGRHSPMLMHCMKQWRLNP 257
Cdd:COG5000 75 TDQLKEQREE-LEERRRYLETILENLPAGVIVLDADGRITLANPAAERLLGIPleELIGKPLEELLPELDLAELLREALE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 258 SLRPPTLKVVPDGPtvQPSFISLNREDDQHVLIFLEDISQIAQQAqqmKLAGLGRLTAGIAHEIRNPLGAISHAAQLLQ- 336
Cdd:COG5000 154 RGWQEEIELTRDGR--RTLLVRASPLRDDGYVIVFDDITELLRAE---RLAAWGELARRIAHEIKNPLTPIQLSAERLRr 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 337 ----ESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEWLQRFVDEY-PGRLRNDSQLHLQLGAGD 411
Cdd:COG5000 229 kladKLEEDREDLERALDTIIRQVDRLKRIVDEFLDFARLPEPQLEPVDLNELLREVLALYePALKEKDIRLELDLDPDL 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 412 IQTRMDPHQLNQVLSNLVQNglrySAQA-HGRGQVWLSLARDPESdlPVLEIIDDGPGVPADKLNNLFEPFFTTESKGTG 490
Cdd:COG5000 309 PEVLADRDQLEQVLINLLKN----AIEAiEEGGEIEVSTRREDGR--VRIEVSDNGPGIPEEVLERIFEPFFTTKPKGTG 382
|
330 340 350
....*....|....*....|....*....|...
gi 489214700 491 LGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG5000 383 LGLAIVKKIVEEHGGTIELESRPGGGTTFTIRL 415
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
190-523 |
2.49e-61 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 205.47 E-value: 2.49e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 190 TVANLEELNALILQRMRTGILVVDSRQAILLANQAALGLLRQ--DDVQGASLGR---HSPMLMHCMKQWRLN--PSLRPP 262
Cdd:COG3852 1 ALRESEELLRAILDSLPDAVIVLDADGRITYVNPAAERLLGLsaEELLGRPLAElfpEDSPLRELLERALAEgqPVTERE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 263 TLKVVPDGP------TVQPSFislNREDDQHVLIFLEDISQIAQQAQQM----KLAGLGRLTAGIAHEIRNPLGAISHAA 332
Cdd:COG3852 81 VTLRRKDGEerpvdvSVSPLR---DAEGEGGVLLVLRDITERKRLERELrraeKLAAVGELAAGLAHEIRNPLTGIRGAA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 333 QLLQESEElDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEWLQRFVD----EYPGRLRndsqLHLQLG 408
Cdd:COG3852 158 QLLERELP-DDELREYTQLIIEEADRLNNLVDRLLSFSRPRPPEREPVNLHEVLERVLEllraEAPKNIR----IVRDYD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 409 AGDIQTRMDPHQLNQVLSNLVQNGlrysAQA-HGRGQVWLSLARDPESDLP--------VLEIIDDGPGVPADKLNNLFE 479
Cdd:COG3852 233 PSLPEVLGDPDQLIQVLLNLVRNA----AEAmPEGGTITIRTRVERQVTLGglrprlyvRIEVIDNGPGIPEEILDRIFE 308
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 489214700 480 PFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG3852 309 PFFTTKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYL 352
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
306-523 |
3.82e-52 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 181.53 E-value: 3.82e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 306 KLAGLGRLTAGIAHEIRNPLGAISHAAQLLQE--SEELDAPD-RRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDL 382
Cdd:COG4191 138 KLAALGELAAGIAHEINNPLAAILGNAELLRRrlEDEPDPEElREALERILEGAERAAEIVRSLRAFSRRDEEEREPVDL 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 383 KEWLQRFVDEYPGRLRNDS-QLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGlRYSAQAHGRGQVWLSLARDPESdlPVLE 461
Cdd:COG4191 218 NELIDEALELLRPRLKARGiEVELDLPPDLPPVLGDPGQLEQVLLNLLINA-IDAMEEGEGGRITISTRREGDY--VVIS 294
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489214700 462 IIDDGPGVPADKLNNLFEPFFTT--ESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG4191 295 VRDNGPGIPPEVLERIFEPFFTTkpVGKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITL 358
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
312-523 |
2.28e-51 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 175.48 E-value: 2.28e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 312 RLTAGIAHEIRNPLGAISHAAQLLQESEELDAPDRR-LTQIIQDQSKRMNLVIENVLQLSR----RRQAEPQQLDLKEWL 386
Cdd:COG2205 18 EFLANVSHELRTPLTSILGAAELLLDEEDLSPEERReLLEIIRESAERLLRLIEDLLDLSRlesgKLSLELEPVDLAELL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 387 QRFVDEYPGRL-RNDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQAhgrGQVWLSLARDPESdlPVLEIIDD 465
Cdd:COG2205 98 EEAVEELRPLAeEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPG---GTITISARREGDG--VRISVSDN 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489214700 466 GPGVPADKLNNLFEPFFTTES----KGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG2205 173 GPGIPEEELERIFERFYRGDNsrgeGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTL 234
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
310-523 |
2.64e-47 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 167.39 E-value: 2.64e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 310 LGRLTAGIAHEIRNPLGAISHAAQLLQEseELDAPDRRLTQIIQDQSKRMNLVIENVLQLSR----RRQAEPQQLDLKEW 385
Cdd:COG0642 110 KSRFLANVSHELRTPLTAIRGYLELLLE--ELDEEQREYLETILRSADRLLRLINDLLDLSRleagKLELEPEPVDLAEL 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 386 LQRFVDEYPGRLRNDS-QLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQAhgrGQVWLSLARdpESDLPVLEIID 464
Cdd:COG0642 188 LEEVVELFRPLAEEKGiELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEG---GTVTVSVRR--EGDRVRISVED 262
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489214700 465 DGPGVPADKLNNLFEPFFTTES----KGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG0642 263 TGPGIPPEDLERIFEPFFRTDPsrrgGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTL 325
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
312-523 |
3.22e-44 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 160.87 E-value: 3.22e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 312 RLTAGIAHEIRNPLGAISHAAQLLQESEELDAPD-RRLTQIIQDQSKRMNLVIENVLQLSR----RRQAEPQQLDLKEWL 386
Cdd:COG5002 167 EFVANVSHELRTPLTSIRGYLELLLDGAADDPEErREYLEIILEEAERLSRLVNDLLDLSRlesgELKLEKEPVDLAELL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 387 QRFVDEYPGRL-RNDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQahgRGQVWLSLARDPESdlPVLEIIDD 465
Cdd:COG5002 247 EEVVEELRPLAeEKGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPE---GGTITVSLREEDDQ--VRISVRDT 321
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489214700 466 GPGVPADKLNNLFEPFFTT------ESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG5002 322 GIGIPEEDLPRIFERFYRVdksrsrETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITL 385
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
188-523 |
5.78e-42 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 158.98 E-value: 5.78e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 188 AETVANLEELNALILQRMRTGILVVDSRQAILLANQAA---LGLLRQDdvqgaSLGRHSPMLmhcmkqWRLNPSLRPPTL 264
Cdd:PRK11360 254 AQALRETRSLNELILESIADGVIAIDRQGKITTMNPAAeviTGLQRHE-----LVGKPYSEL------FPPNTPFASPLL 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 265 KVVPDGPTVQPSFISLNRED-------------DQH-----VLIFLEDISQIAQQAQQM----KLAGLGRLTAGIAHEIR 322
Cdd:PRK11360 323 DTLEHGTEHVDLEISFPGRDrtielsvstsllhNTHgemigALVIFSDLTERKRLQRRVarqeRLAALGELVAGVAHEIR 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 323 NPLGAISHAAQLLQESEElDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEWLQR---FVDEYPGRLRN 399
Cdd:PRK11360 403 NPLTAIRGYVQIWRQQTS-DPPSQEYLSVVLREVDRLNKVIDQLLEFSRPRESQWQPVSLNALVEEvlqLFQTAGVQARV 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 400 DSQLHLQlgaGDIQTRM-DPHQLNQVLSNLVQNGLrysaQA-HGRGQVWLSLARDPESDLpVLEIIDDGPGVPADKLNNL 477
Cdd:PRK11360 482 DFETELD---NELPPIWaDPELLKQVLLNILINAV----QAiSARGKIRIRTWQYSDGQV-AVSIEDNGCGIDPELLKKI 553
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 489214700 478 FEPFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:PRK11360 554 FDPFFTTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYL 599
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
185-525 |
2.12e-40 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 149.55 E-value: 2.12e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 185 EERAETVANLEELNALIlQRMRTGILVVDSRQAILLANQAALGL--LRQDDVQGASLGRHSPMLMHcMKQWRLNPSLRPP 262
Cdd:COG5807 17 QEFKLTEDSEFKFKQLF-DSILEFVFFIDSKGEILECNDFAEDLygLSQNEYIGKTFVEEKCILKD-EQLYNKEAFDRIE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 263 TLKVVPDGP--TVQPSFISLNREDDQHVLIFL---EDISQIAQQAQQMKLAGLGRLTAGIAHEIRNPLGAISHAAQLLQE 337
Cdd:COG5807 95 ISYLTKNGEfdEIIYPIYYKDGVILGLITVYRditKRKEAEDKLLRSEKLSVAGELAAGIAHEIRNPLTSIKGFLQLLQE 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 338 SEELDAPDRRLtQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEWLQRFVD--EYPGRLRNdSQLHLQLGAGDIQTR 415
Cdd:COG5807 175 SREDSEREEYF-NIIISEIDRINTIITELLVLSKPKKFNFKKLNLNDVLEDVIAllSTEAILKN-ISIKYDLADDEPVIN 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 416 MDPHQLNQVLSNLVQNGLrySAQAHGrGQVWLSLARdpESDLPVLEIIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYL 495
Cdd:COG5807 253 GDKNQLKQVFINLIKNAI--EAMETG-GNITIKTYV--EGDFVVISVKDEGIGIPEEVLEKIGEPFFTTKEEGTGLGLSI 327
|
330 340 350
....*....|....*....|....*....|
gi 489214700 496 SRELCESNQARIDYRNREEGGGCFRITFAH 525
Cdd:COG5807 328 CKKIIEEHNGTIEVESKPGKGTTFTIYLPL 357
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
306-523 |
2.39e-37 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 143.96 E-value: 2.39e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 306 KLAGLGRLTAGIAHEIRNPLGAISHAAQLLQESEELDapDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEW 385
Cdd:COG5809 266 KLSVVGELAAGIAHEIRNPLTSLKGFIQLLKDTIDEE--QKTYLDIMLSELDRIESIISEFLVLAKPQAIKYEPKDLNTL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 386 LQRFVDEY-PGRLRNDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRysAQAHGrGQVWLSLARDPESDLpVLEIID 464
Cdd:COG5809 344 IEEVIPLLqPQALLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIE--AMPEG-GNITIETKAEDDDKV-VISVTD 419
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 489214700 465 DGPGVPADKLNNLFEPFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG5809 420 EGCGIPEERLKKLGEPFYTTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITL 478
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
306-528 |
3.60e-35 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 137.19 E-value: 3.60e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 306 KLAGLGRLTAGIAHEIRNPLGAISHAAQLLQEsEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEW 385
Cdd:COG5808 237 KLELIGTFAASTAHEIRNPLTSIKGFIQLLQE-KYPELEDQKYFDIIQEEIQRINQIVSEFLVLGKPTAKKLELDDLNEL 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 386 LQRFVD--EYPGRLRNdSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQahgRGQVWLSLARDPESdlPVLEII 463
Cdd:COG5808 316 IEEILSiiDSEANLKN-IRVEKQSLDEPLHIKCDKDRIKQVLLNLIKNAIEAMKE---GGKLTISIENDDEK--AVIEVI 389
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489214700 464 DDGPGVPADKLNNLFEPFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITFahPRK 528
Cdd:COG5808 390 DNGEGIPEDIIDEIFEPFVTTKEGGTGLGLSVCKRIVEMHGGEIDIESEEGKGTTFTIRL--PLK 452
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
195-523 |
6.31e-35 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 137.17 E-value: 6.31e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 195 EELNALIlQRMRTGILVVDSRQAILLANQAALGLLR--QDDVQGASLGRHSPMLMHCMKQWRLNPSLRPPTLKVV----- 267
Cdd:COG5805 157 ERLQTLI-ENSPDLICVIDTDGRILFINESIERLFGapREELIGKNLLELLHPCDKEEFKERIESITEVWQEFIIereii 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 268 -PDGP------TVQPSFISLNREddQHVLIFLEDISQIAQQAQQM----KLAGLGRLTAGIAHEIRNPLGAISHAAQLLQ 336
Cdd:COG5805 236 tKDGRiryfeaVIVPLIDTDGSV--KGILVILRDITEKKEAEELMarseKLSIAGQLAAGIAHEIRNPLTSIKGFLQLLQ 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 337 ESEEldaPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEWLQRFVD--EYPGRLRNdSQLHLQLGAGDIQT 414
Cdd:COG5805 314 PGIE---DKEEYFDIMLSELDRIESIISEFLALAKPQAVNKEKENINELIQDVVTllETEAILHN-IQIRLELLDEDPFI 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 415 RMDPHQLNQVLSNLVQNGLrySAQAHGrGQVWLSLArdPESDLPVLEIIDDGPGVPADKLNNLFEPFFTTESKGTGLGLY 494
Cdd:COG5805 390 YCDENQIKQVFINLIKNAI--EAMPNG-GTITIHTE--EEDNSVIIRVIDEGIGIPEERLKKLGEPFFTTKEKGTGLGLM 464
|
330 340
....*....|....*....|....*....
gi 489214700 495 LSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG5805 465 VSYKIIENHNGTIDIDSKVGKGTTFTITL 493
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
318-523 |
1.30e-31 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 127.27 E-value: 1.30e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 318 AHEIRNPLGAISHAAQLLQEseELDAPDR-RLTQIIQDQSKRMNLVIENVLQLS----RRRQAEPQQLDLKEWLQRFVDE 392
Cdd:PRK11100 264 THELKSPLAAIRGAAELLQE--DPPPEDRaRFTGNILTQSARLQQLIDRLLELArleqRQELEVLEPVALAALLEELVEA 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 393 YPGRLRNdSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQAhgrGQVWLSLARDpeSDLPVLEIIDDGPGVPAD 472
Cdd:PRK11100 342 REAQAAA-KGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEG---GTITLSAEVD--GEQVALSVEDQGPGIPDY 415
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 489214700 473 KLNNLFEPFFT-----TESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:PRK11100 416 ALPRIFERFYSlprpaNGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTL 471
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
416-523 |
9.66e-27 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 104.27 E-value: 9.66e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 416 MDPHQLNQVLSNLVQNGLRYSAQahgRGQVWLSLARDPEsDLpVLEIIDDGPGVPADKLNNLFEPFFTT-----ESKGTG 490
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPE---GGRITVTLERDGD-HV-EITVEDNGPGIPPEDLEKIFEPFFRTdkrsrKIGGTG 75
|
90 100 110
....*....|....*....|....*....|...
gi 489214700 491 LGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:smart00387 76 LGLSIVKKLVELHGGEISVESEPGGGTTFTITL 108
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
306-521 |
6.35e-25 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 107.56 E-value: 6.35e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 306 KLAGLGRLTAGIAHEIRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRrrqaePQQLDLKew 385
Cdd:PRK10364 233 KLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVK-----PTHLALQ-- 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 386 lqrfvdeyPGRLRNDSQLHLQLGAGDIQTR----------------MDPHQLNQVLSNLVQNGLrysaQAHGRGQVwLSL 449
Cdd:PRK10364 306 --------AVDLNDLINHSLQLVSQDANSReiqlrftandtlpeiqADPDRLTQVLLNLYLNAI----QAIGQHGV-ISV 372
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489214700 450 ARDPESDLPVLEIIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRI 521
Cdd:PRK10364 373 TASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTL 444
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
112-523 |
7.73e-25 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 106.47 E-value: 7.73e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 112 VAIANILLRGRIGLVIAAAASLGLLYLTFFLSLSSPDATNHYVQAGGLGTLCFAAALVIQALVRRQEQTETLAEeraetV 191
Cdd:COG3290 5 LLLLLLLLILLILILILLLLLLIILLLILLLVLLLLLFLLFVIILLLLLLILLLILLLLLLLLLAALLLKLLEE-----I 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 192 ANLEELNALILQRMRTGILVVDSRQAILLANQAALGLLRQDDV--QGASLGRHSPMLMHCMKQWRLNPSLRPPTLKVVPD 269
Cdd:COG3290 80 ARLVEEREAVLESIREGVIAVDRDGRITLINDAARRLLGLDAIgrPIDEVLAEVLETGERDEEILLNGRVLVVNRVPIRD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 270 GPTVQPSFISLNREDDQHVLIfledisqiaqqaqqMKLAGLGRLTA---GIAHEIRNPLGAISHAAQLLQESEELDapdr 346
Cdd:COG3290 160 DGRVVGAVATFRDRTELERLE--------------EELEGVKELAEalrAQRHDFRNHLHTISGLLQLGEYDEALE---- 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 347 RLTQIIQDQSKRMNLVIENV-------LQLSRRRQAEPQQLDLkewlqrfvdeypgRLRNDSQLHlqlgagdiQTRMDPH 419
Cdd:COG3290 222 YIDEISEELQELIDSLLSRIgnpvlaaLLLGKAARARERGIDL-------------TIDIDSDLP--------DLPLSDT 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 420 QLNQVLSNLVQNGLRYSA-QAHGRGQVWLSLaRDPESDLpVLEIIDDGPGVPADKLNNLFEPFFTT-ESKGTGLGLYLSR 497
Cdd:COG3290 281 DLVTILGNLLDNAIEAVEkLPEEERRVELSI-RDDGDEL-VIEVEDSGPGIPEELLEKIFERGFSTkLGEGRGLGLALVK 358
|
410 420
....*....|....*....|....*.
gi 489214700 498 ELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG3290 359 QIVEKYGGTIEVESEEGEGTVFTVRL 384
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
310-523 |
1.07e-23 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 104.48 E-value: 1.07e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 310 LGRLTAGIAHEIRNPLGAISHAAQLLQE--SEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSR--RRQAEPQQLDLKEW 385
Cdd:COG4251 282 LEQFAYVASHDLREPLRKISGFSQLLEEdyGDKLDEEGREYLERIRDAAERMQALIDDLLAYSRvgRQELEFEPVDLNEL 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 386 LQRFVDEYPGRLRnDSQLHLQLGAGdIQTRMDPHQLNQVLSNLVQNGLRYSAQAHgRGQVWLSLARDPesDLPVLEIIDD 465
Cdd:COG4251 362 LEEVLEDLEPRIE-ERGAEIEVGPL-PTVRGDPTLLRQVFQNLISNAIKYSRPGE-PPRIEIGAEREG--GEWVFSVRDN 436
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489214700 466 GPGVPADKLNNLFEPFFT----TESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG4251 437 GIGIDPEYAEKIFEIFQRlhsrDEYEGTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTL 498
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
416-523 |
1.52e-23 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 95.13 E-value: 1.52e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 416 MDPHQLNQVLSNLVQNGLRYSAQAhgrGQVWLSLARDpesDLPVLEIIDDGPGVPADKLNNLFEPFFT---TESKGTGLG 492
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKA---GEITVTLSEG---GELTLTVEDNGIGIPPEDLPRIFEPFSTadkRGGGGTGLG 74
|
90 100 110
....*....|....*....|....*....|.
gi 489214700 493 LYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:pfam02518 75 LSIVRKLVELLGGTITVESEPGGGTTVTLTL 105
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
306-523 |
1.10e-22 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 100.33 E-value: 1.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 306 KLAGLGRLTAGIAHEIRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEW 385
Cdd:COG5806 197 KLEVVSELAASIAHEVRNPLTVVRGFIQLLQEPELSDEKRKQYIRIALEELDRAEAIITDYLTFAKPQPEKLEKIDVSEE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 386 LQRFVDEY-PGRLRNDSQLHLQLgAGDIQTRMDPHQLNQVLSNLVQNGLRysAQAHGrGQVWLSLARDPESdlPVLEIID 464
Cdd:COG5806 277 LEHVIDVLsPYANMNNVEIQTEL-EPGLYIEGDRQKLQQCLINIIKNGIE--AMPNG-GTLTIDVSIDKNK--VIISIKD 350
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 489214700 465 DGPGVPADKLNNLFEPFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:COG5806 351 TGVGMTKEQLERLGEPYFSTKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTTFTITL 409
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
306-521 |
2.56e-21 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 97.83 E-value: 2.56e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 306 KLAGLGRLTAGIAHEIRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEW 385
Cdd:PRK13837 446 RLEAVGTLASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGARARLIIDQILAFGRKGERNTKPFDLSEL 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 386 LQRFVDEYPGRLRNDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNglrySAQA-HGRGQVWLSLARD------------ 452
Cdd:PRK13837 526 VTEIAPLLRVSLPPGVELDFDQDQEPAVVEGNPAELQQVLMNLCSN----AAQAmDGAGRVDISLSRAklrapkvlshgv 601
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 453 -PESDLPVLEIIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRI 521
Cdd:PRK13837 602 lPPGRYVLLRVSDTGAGIDEAVLPHIFEPFFTTRAGGTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDV 671
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
417-523 |
5.93e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 87.98 E-value: 5.93e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 417 DPHQLNQVLSNLVQNGLR-YSAQAHGRGQVWLSLARDPESDLpVLEIIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYL 495
Cdd:cd16944 1 DTTQISQVLTNILKNAAEaIEGRPSDVGEVRIRVEADQDGRI-VLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGLAI 79
|
90 100
....*....|....*....|....*...
gi 489214700 496 SRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:cd16944 80 VKKIMEEHGGRISLSNREAGGACIRIIL 107
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
313-527 |
9.42e-20 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 91.90 E-value: 9.42e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 313 LTAGIAHEIRNPLGAISHAAQLLqeSEEldapDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEP-QQLDLKEWLQRFVD 391
Cdd:PRK09467 232 LMAGVSHDLRTPLTRIRLATEMM--SEE----DGYLAESINKDIEECNAIIEQFIDYLRTGQEMPmEMADLNALLGEVIA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 392 EYPGRLRndsQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYsaqahGRGQVWLSLARDpeSDLPVLEIIDDGPGVPA 471
Cdd:PRK09467 306 AESGYER---EIETALQPGPIEVPMNPIAIKRALANLVVNAARY-----GNGWIKVSSGTE--GKRAWFQVEDDGPGIPP 375
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 472 DKLNNLFEPFFTTE----SKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITFAHPR 527
Cdd:PRK09467 376 EQLKHLFQPFTRGDsargSSGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLPLTT 435
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
421-522 |
3.54e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 82.83 E-value: 3.54e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRysAQAHG---RGQVWLSLARDpESDLPVLEIIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYLSR 497
Cdd:cd16920 1 IQQVLINLVRNGIE--AMSEGgceRRELTIRTSPA-DDRAVTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICR 77
|
90 100
....*....|....*....|....*
gi 489214700 498 ELCESNQARIDYRNREEGGGCFRIT 522
Cdd:cd16920 78 SIIEAHGGRLSVESPAGGGATFQFT 102
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
421-521 |
4.10e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 82.50 E-value: 4.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLrysAQAHGRGQVWLSLARDPESDLPVLEIIDDGPGVPADKLNNLFEPFFTTE--SKGTGLGLYLSRE 498
Cdd:cd16976 1 IQQVLMNLLQNAL---DAMGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKpvGKGTGLGLSISYG 77
|
90 100
....*....|....*....|...
gi 489214700 499 LCESNQARIDYRNREEGGGCFRI 521
Cdd:cd16976 78 IVEEHGGRLSVANEEGAGARFTF 100
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
313-509 |
6.48e-19 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 88.21 E-value: 6.48e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 313 LTAGIAHEIRNPLGAISHAAQLLQESeeldAPDRRL---TQIIQDQSKRM-NLVienvlqlsrRRQAEPQQLDLKEWLQ- 387
Cdd:PRK11073 133 LVRGLAHEIKNPLGGLRGAAQLLSKA----LPDPALteyTKVIIEQADRLrNLV---------DRLLGPQRPGTHVTESi 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 388 RFVDEYPGRLrndsqLHLQLGAGDIQTR----------MDPHQLNQVLSNLVQNGLRYSAQAHG--------------RG 443
Cdd:PRK11073 200 HKVAERVVQL-----VSLELPDNVRLIRdydpslpelaHDPDQIEQVLLNIVRNALQALGPEGGtitlrtrtafqltlHG 274
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489214700 444 QVWLSLARdpesdlpvLEIIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYLSRELCESNQARIDY 509
Cdd:PRK11073 275 ERYRLAAR--------IDIEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEF 332
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
313-520 |
1.22e-18 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 88.12 E-value: 1.22e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 313 LTAGIAHEIRNPLgaishaAQL---LQESEELDAPDRrltQIIQDQSKRMNLVIENVLQLSR--RRQAE--PQQLDLKEW 385
Cdd:PRK10604 215 LIDGIAHELRTPL------VRLryrLEMSDNLSAAES---QALNRDIGQLEALIEELLTYARldRPQNElhLSEPDLPAW 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 386 LQRFVDEYPGrLRNDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSaqahgRGQVWLSLARDpeSDLPVLEIIDD 465
Cdd:PRK10604 286 LSTHLADIQA-VTPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRYA-----HSRVRVSLLLD--GNQACLIVEDD 357
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489214700 466 GPGVPADKLNNLFEPFFTTE------SKGTGLGLYLSRELCESNQARIDYRNREEGGGCFR 520
Cdd:PRK10604 358 GPGIPPEERERVFEPFVRLDpsrdraTGGCGLGLAIVHSIALAMGGSVNCDESELGGARFS 418
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
421-522 |
2.60e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 77.37 E-value: 2.60e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRYSaqahgRGQVWLSLARDpeSDLPVLEIIDDGPGVPADKLNNLFEPFF------TTESKGTGLGLY 494
Cdd:cd16949 1 LARALENVLRNALRYS-----PSKILLDISQD--GDQWTITITDDGPGVPEDQLEQIFLPFYrvdsarDRESGGTGLGLA 73
|
90 100
....*....|....*....|....*...
gi 489214700 495 LSRELCESNQARIDYRNREEGGGCFRIT 522
Cdd:cd16949 74 IAERAIEQHGGKIKASNRKPGGLRVRIW 101
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
421-522 |
3.17e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 77.53 E-value: 3.17e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRYSAqahgRGQVWLSLARDPESDLPVL---EIIDDGPGVPADKLNNLFEPFFTTES------KGTGL 491
Cdd:cd16922 1 LRQILLNLLGNAIKFTE----EGEVTLRVSLEEEEEDGVQlrfSVEDTGIGIPEEQQARLFEPFSQADSsttrkyGGTGL 76
|
90 100 110
....*....|....*....|....*....|.
gi 489214700 492 GLYLSRELCESNQARIDYRNREEGGGCFRIT 522
Cdd:cd16922 77 GLAISKKLVELMGGDISVESEPGQGSTFTFT 107
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
418-525 |
2.28e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 74.77 E-value: 2.28e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 418 PHQLNQVLSNLVQNglrySAQA-HGRGQVWLSLARDPESDLpvLEIIDDGPGVPADKLNNLFEPFFTTE--SKGTGLGLY 494
Cdd:cd16943 1 PSQLNQVLLNLLVN----AAQAmEGRGRITIRTWAHVDQVL--IEVEDTGSGIDPEILGRIFDPFFTTKpvGEGTGLGLS 74
|
90 100 110
....*....|....*....|....*....|.
gi 489214700 495 LSRELCESNQARIDYRNREEGGGCFRITFAH 525
Cdd:cd16943 75 LSYRIIQKHGGTIRVASVPGGGTRFTIILPI 105
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
421-521 |
2.57e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 71.71 E-value: 2.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRYsaqahgrGQVWLSLARDPESDLPVLEIIDDGPGVPADKLNNLFEPFFTTES----KGTGLGLYLS 496
Cdd:cd16950 1 LKRVLSNLVDNALRY-------GGGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNargtSGTGLGLAIV 73
|
90 100
....*....|....*....|....*
gi 489214700 497 RELCESNQARIDYRNREEGGGCFRI 521
Cdd:cd16950 74 QRISDAHGGSLTLANRAGGGLCARI 98
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
312-522 |
3.09e-15 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 77.30 E-value: 3.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 312 RLTAGIAHEIRNPLGAISHAAQLLQ-----ESEELDAPDR-RLTQIIQDQSKRMNLVIENVLQLSRRRQAE----PQQLD 381
Cdd:PRK09303 153 RVLAMLAHDLRTPLTAASLALETLElgqidEDTELKPALIeQLQDQARRQLEEIERLITDLLEVGRTRWEAlrfnPQKLD 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 382 LKEWLQRFVDEYPGRLRNDSQlHLQLgagDIQTRM-----DPHQLNQVLSNLVQNGLRYSAQAhgrGQVWLSLARDPESD 456
Cdd:PRK09303 233 LGSLCQEVILELEKRWLAKSL-EIQT---DIPSDLpsvyaDQERIRQVLLNLLDNAIKYTPEG---GTITLSMLHRTTQK 305
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489214700 457 LPVlEIIDDGPGVPADKLNNLFEPFF------TTEskGTGLGLYLSRELCESNQARIDYRNREEGGGCFRIT 522
Cdd:PRK09303 306 VQV-SICDTGPGIPEEEQERIFEDRVrlprdeGTE--GYGIGLSVCRRIVRVHYGQIWVDSEPGQGSCFHFT 374
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-524 |
3.38e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 68.85 E-value: 3.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 424 VLSNLVQNGLRYSAQAhgrGQVWLSLARDPESdlPVLEIIDDGPGVPADKLNNLFEPFFT-----TESKGTGLGLYLSRE 498
Cdd:cd16948 9 IIGQIVSNALKYSKQG---GKIEIYSETNEQG--VVLSIKDFGIGIPEEDLPRVFDKGFTgengrNFQESTGMGLYLVKK 83
|
90 100
....*....|....*....|....*..
gi 489214700 499 LCESNQARIDYRNrEEGGGC-FRITFA 524
Cdd:cd16948 84 LCDKLGHKIDVES-EVGEGTtFTITFP 109
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
312-516 |
3.65e-14 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 74.69 E-value: 3.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 312 RLTAGIAHEIRNPLGAI---SHAAQLLQESEEldAPDRRLTQIIQ--DQSKRMnlvIENVLQLSR----RRQAEPQQLDL 382
Cdd:PRK10337 239 RFTSDAAHELRSPLAALkvqTEVAQLSDDDPQ--ARKKALLQLHAgiDRATRL---VDQLLTLSRldslDNLQDVAEIPL 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 383 KEWLQRFV-DEYPGRLRNDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQAhgrGQVWLSLARDpesdlpVLE 461
Cdd:PRK10337 314 EDLLQSAVmDIYHTAQQAGIDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQG---SVVDVTLNAR------NFT 384
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 489214700 462 IIDDGPGVPADKLNNLFEPFFT---TESKGTGLGLYLSRELCESNQARIDYRNREEGG 516
Cdd:PRK10337 385 VRDNGPGVTPEALARIGERFYRppgQEATGSGLGLSIVRRIAKLHGMNVSFGNAPEGG 442
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
310-371 |
5.27e-14 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 66.85 E-value: 5.27e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489214700 310 LGRLTAGIAHEIRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSR 371
Cdd:cd00082 4 KGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
417-523 |
5.62e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 68.26 E-value: 5.62e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 417 DPHQLNQVLSNLVQNGLRYSaqaHGRGQVWLSLARDPesDLPVLEIIDDGPGVPADKLNNLFEPFFTTESK------GTG 490
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYT---DTGGKLRIRAAQTP--QEVRLDVEDSAPGVSDDQLARLFERFYRVESSrnrasgGSG 75
|
90 100 110
....*....|....*....|....*....|...
gi 489214700 491 LGLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:cd16946 76 LGLAICHNIALAHGGTISAEHSPLGGLRLVLTL 108
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
310-374 |
2.41e-13 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 64.89 E-value: 2.41e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489214700 310 LGRLTAGIAHEIRNPLGAISHAAQLLQESeELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQ 374
Cdd:smart00388 2 KREFLANLSHELRTPLTAIRGYLELLLDT-ELSEEQREYLETILREAERLLRLINDLLDLSRIEA 65
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
314-518 |
3.65e-13 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 70.77 E-value: 3.65e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 314 TAGIAHEIRNPLGAISHAAQLLQESEELDAPDrrLTQIIqDQskrMNLVIENVLQLSRRRQA----------------EP 377
Cdd:PRK10755 141 TADVAHELRTPLAGIRLHLELLEKQHHIDVAP--LIARL-DQ---MMHTVEQLLQLARAGQSfssghyqtvklledviLP 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 378 QQLDLKEWLQrfvdeypgrLRnDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQAhgrGQVWLSLARDPESdl 457
Cdd:PRK10755 215 SQDELSEMLE---------QR-QQTLLLPESAADITVQGDATLLRLLLRNLVENAHRYSPEG---STITIKLSQEDGG-- 279
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489214700 458 PVLEIIDDGPGVPADKLNNLFEPFFTTESK--GTGLGLYLSRELCESNQARIDYRNREEGGGC 518
Cdd:PRK10755 280 AVLAVEDEGPGIDESKCGELSKAFVRMDSRygGIGLGLSIVSRITQLHHGQFFLQNRQERSGT 342
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
306-493 |
3.97e-13 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 71.63 E-value: 3.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 306 KLAGLGRLTAGIAHEIRNPLGAISHAAQLLQ---ESEELDAPD-RRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLD 381
Cdd:PRK13557 159 KMEALGQLTGGIAHDFNNLLQVMSGYLDVIQaalSHPDADRGRmARSVENIRAAAERAATLTQQLLAFARKQRLEGRVLN 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 382 LKEWLQRFVDEYPGRLRNDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGlrYSAQAHG-------RGQVWLSLARDPE 454
Cdd:PRK13557 239 LNGLVSGMGELAERTLGDAVTIETDLAPDLWNCRIDPTQAEVALLNVLINA--RDAMPEGgrvtirtRNVEIEDEDLAMY 316
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 489214700 455 SDLP-----VLEIIDDGPGVPADKLNNLFEPFFTTES--KGTGLGL 493
Cdd:PRK13557 317 HGLPpgryvSIAVTDTGSGMPPEILARVMDPFFTTKEegKGTGLGL 362
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
310-374 |
5.58e-13 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 63.77 E-value: 5.58e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489214700 310 LGRLTAGIAHEIRNPLGAISHAAQLLQEsEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQ 374
Cdd:pfam00512 2 KSEFLANLSHELRTPLTAIRGYLELLRD-EKLDEEQREYLETILRSAERLLRLINDLLDLSRIEA 65
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
306-507 |
7.93e-13 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 70.87 E-value: 7.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 306 KLAGLGRLTAGIAHEIRNPLGAIS---HAAQLLQESEELDAPDRRLTQIIQdQSKRMNLVIENVLQLSRRRQAEPQQLDL 382
Cdd:COG4192 429 KMAVVGQTMTSLAHELNQPLNAMSmylFSAKKALEQENYAQLPTSLDKIEG-LIERMDKIIKSLRQFSRKSDTPLQPVDL 507
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 383 KEWLQRFVDEYPGRL-RNDSQLHLQlgaGDIQTRMDPHQLNQVLSNLVQNGLRYSAqahgrGQVWLSLARDPESDLPVLE 461
Cdd:COG4192 508 RQVIEQAWELVESRAkPQQITLHIP---DDLMVQGDQVLLEQVLVNLLVNALDAVA-----TQPQISVDLLSNAENLRVA 579
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 489214700 462 IIDDGPGVP-ADKLnnlFEPFFTTESKGTGLGLYLSRELCESNQARI 507
Cdd:COG4192 580 ISDNGNGWPlVDKL---FTPFTTTKEVGLGLGLSICRSIMQQFGGDL 623
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
421-521 |
8.45e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 64.90 E-value: 8.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRYSAQAHGRgqvwLSLARDPESDLPVLEIIDDGPGVPADKLNNLFEPFFTTESKG------TGLGLY 494
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDTGR----ITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANeafgqhSGLGLS 76
|
90 100 110
....*....|....*....|....*....|.
gi 489214700 495 LSRELCESNQARIDYRNREEG----GGCFRI 521
Cdd:cd16953 77 ISRQIIEAHGGISVAENHNQPgqviGARFTV 107
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
421-508 |
9.28e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 64.73 E-value: 9.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRYSAQAHG------RGQVWLSLARdPESDLPV-LEIIDDGPGVPADKLNNLFEPFFTTESKGTGLGL 493
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSGGeiilrtRTQRQVTLGH-PRHRLALrVSVIDNGPGIPPDLQDTIFYPMVSGRENGTGLGL 79
|
90
....*....|....*
gi 489214700 494 YLSRELCESNQARID 508
Cdd:cd16918 80 AIAQNIVSQHGGVIE 94
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
315-521 |
8.45e-12 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 68.01 E-value: 8.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 315 AGIAHEIRNPLGAISHAAQLLQEsEELDAPDRRLTQIIQDQSKRMNLVIENVLQLS-----------RRRQAEPQQLdLK 383
Cdd:PRK11466 449 AAMSHEIRTPLYGILGTAQLLAD-NPALNAQRDDLRAITDSGESLLTILNDILDYSaieaggknvsvSDEPFEPRPL-LE 526
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 384 EWLQRF---VDEYPGRLRNDSqlhlqlgAGDIQTRM--DPHQLNQVLSNLVQNGLRYSAqahgRGQVWLSLARDPESDLp 458
Cdd:PRK11466 527 STLQLMsgrVKGRPIRLATDI-------ADDLPTALmgDPRRIRQVITNLLSNALRFTD----EGSIVLRSRTDGEQWL- 594
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489214700 459 vLEIIDDGPGVPADKLNNLFEPFFTTESK--GTGLGLYLSRELCESNQARIDYRNREEGGGCFRI 521
Cdd:PRK11466 595 -VEVEDSGCGIDPAKLAEIFQPFVQVSGKrgGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCL 658
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
313-522 |
6.32e-11 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 65.06 E-value: 6.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 313 LTAGIAHEIRNPLGAISHAAQLLQE--SEELDAPDRRLTQIIQDQSKRMNLViENVLQLSRRrQAEPQQLDlKEWLQrfV 390
Cdd:PRK10490 667 LLAALSHDLRTPLTVLFGQAEILTLdlASEGSPHARQASEIRQQVLNTTRLV-NNLLDMARI-QSGGFNLR-KEWLT--L 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 391 DEYPGR-LR------NDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQahgrgQVWLSLARDPESDLPVLEII 463
Cdd:PRK10490 742 EEVVGSaLQmlepglSGHPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGA-----QAEIGIDAHVEGERLQLDVW 816
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489214700 464 DDGPGVPADKLNNLFEPFF--TTESK--GTGLGLYLSRELCESNQARIDYRNREEGGGCFRIT 522
Cdd:PRK10490 817 DNGPGIPPGQEQLIFDKFArgNKESAipGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVT 879
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
424-522 |
1.09e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 58.45 E-value: 1.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 424 VLSNLVQNGLRYSA-QAHGRGQVWLSLaRDPESDLpVLEIIDDGPGVPADKLNNLFEPFFTT-ESKGTGLGLYLSRELCE 501
Cdd:cd16915 4 IVGNLIDNALDALAaTGAPNKQVEVFL-RDEGDDL-VIEVRDTGPGIAPELRDKVFERGVSTkGQGERGIGLALVRQSVE 81
|
90 100
....*....|....*....|.
gi 489214700 502 SNQARIDYRNREEGGGCFRIT 522
Cdd:cd16915 82 RLGGSITVESEPGGGTTFSIR 102
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
416-523 |
1.40e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 59.18 E-value: 1.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 416 MDPHQLNQVLSNLVQNGLRYSAqahgrGQVWLSLARDPESdlpvLEII--DDGPGVPADKLNNLFE--PFFTTESKGTGL 491
Cdd:cd16954 33 GERNDLMELLGNLLDNACKWCL-----EFVEVTARQTDGG----LHLIvdDDGPGVPESQRSKIFQrgQRLDEQRPGQGL 103
|
90 100 110
....*....|....*....|....*....|..
gi 489214700 492 GLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:cd16954 104 GLAIAKEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
409-522 |
2.34e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 57.80 E-value: 2.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 409 AGDIQTRMDPHQLNQVLSNLVQNGLRYSAQAhgrGQVWLSLArdpESDLPVLEIIDDGPGVPADKLNNLFEPFF---TTE 485
Cdd:cd16940 2 AADIQVQGDALLLFLLLRNLVDNAVRYSPQG---SRVEIKLS---ADDGAVIRVEDNGPGIDEEELEALFERFYrsdGQN 75
|
90 100 110
....*....|....*....|....*....|....*..
gi 489214700 486 SKGTGLGLYLSRELCESNQARIDYRNREEGGgcFRIT 522
Cdd:cd16940 76 YGGSGLGLSIVKRIVELHGGQIFLGNAQGGG--LEAW 110
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
315-507 |
2.44e-10 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 62.73 E-value: 2.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 315 AGIAHEIRNPLgaishaAQLLQESEELDAPDRRLT--QIIQDQSKRMNL--VIENVLQLS-RRRQA---EPQQLDLKEWL 386
Cdd:PRK10549 245 ADISHELRTPL------AVLRGELEAIQDGVRKFTpeSVASLQAEVGTLtkLVDDLHQLSlSDEGAlayRKTPVDLVPLL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 387 QRFVDEYPGRLRnDSQLHLQLGAGDIQTRM-DPHQLNQVLSNLVQNGLRYSAQAhgrGQVWLSLARDPESDlpVLEIIDD 465
Cdd:PRK10549 319 EVAGGAFRERFA-SRGLTLQLSLPDSATVFgDPDRLMQLFNNLLENSLRYTDSG---GSLHISAEQRDKTL--RLTFADS 392
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 489214700 466 GPGVPADKLNNLFEPFFTTE------SKGTGLGLYLSRELCESNQARI 507
Cdd:PRK10549 393 APGVSDEQLQKLFERFYRTEgsrnraSGGSGLGLAICLNIVEAHNGRI 440
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
421-522 |
4.12e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 57.05 E-value: 4.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRYSAQahgrgQVWLSLARDPESdlPVLEIIDDGPGVPADKLNNLFEPFF------TTESKGTGLGLY 494
Cdd:cd16939 1 MARALDNLLRNALRYAHR-----TVRIALLVSGGR--LTLIVEDDGPGIPAAARERVFEPFVrldpsrDRATGGFGLGLA 73
|
90 100
....*....|....*....|....*...
gi 489214700 495 LSRELCESNQARIDYRNREEGGGCFRIT 522
Cdd:cd16939 74 IVHRVALWHGGHVECDDSELGGACFRLT 101
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
417-519 |
8.07e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 56.31 E-value: 8.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 417 DPHQLNQVLSNLVQNGLRYSAQAhgrGQVWLSLARDPESdlPVLEIIDDGPGVPADKLNNLFEPFFT-----TESKGTGL 491
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEG---GLIALQLEADTEG--IELLVFDEGSGIPDYALNRVFERFYSlprphSGQKSTGL 75
|
90 100
....*....|....*....|....*...
gi 489214700 492 GLYLSRELCESNQARIDYRNREEGGGCF 519
Cdd:cd16945 76 GLAFVQEVAQLHGGRITLRNRPDGVLAF 103
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
315-529 |
9.39e-10 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 60.79 E-value: 9.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 315 AGIAHEIRNPLGAISHAAQLLQEsEELDAPDR-RLTQIIQDQSKRMNLVIENVLQLSrRRQAEPqQLDLKEwlqrFVDeY 393
Cdd:PRK11006 209 ANVSHELRTPLTVLQGYLEMMQD-QPLEGALReKALHTMREQTQRMEGLVKQLLTLS-KIEAAP-TIDLNE----KVD-V 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 394 PGRLRNDSQLHLQLGAG--DIQTRMDPH--------QLNQVLSNLVQNGLRYSAQAHGRGQVWLSLARDPEsdlpvLEII 463
Cdd:PRK11006 281 PMMLRVLEREAQTLSQGkhTITFEVDNSlkvfgnedQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGAE-----FSVE 355
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489214700 464 DDGPGVPADKLNNLFEPFF------TTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFriTFAHPRKL 529
Cdd:PRK11006 356 DNGPGIAPEHIPRLTERFYrvdkarSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGKGTRF--SFVLPERL 425
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
317-499 |
2.51e-09 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 60.04 E-value: 2.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 317 IAHEIRNPLGAISHAAQLLQESEeLDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRR--QAE--PQQLDLKEWLQRFVDE 392
Cdd:PRK15347 405 ISHEIRTPLNGVLGALELLQNTP-LTAEQMDLADTARQCTLSLLAIINNLLDFSRIEsgQMTlsLEETALLPLLDQAMLT 483
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 393 YPGRLRNDS-QLHLQLGAGDIQT-RMDPHQLNQVLSNLVQNGLRYSAQahgrGQVWLSLARdpESDLPVLEIIDDGPGVP 470
Cdd:PRK15347 484 IQGPAQSKSlTLRTFVGAHVPLYlHLDSLRLRQILVNLLGNAVKFTET----GGIRLRVKR--HEQQLCFTVEDTGCGID 557
|
170 180 190
....*....|....*....|....*....|.
gi 489214700 471 ADKLNNLFEPFFTTE--SKGTGLGLYLSREL 499
Cdd:PRK15347 558 IQQQQQIFTPFYQADthSQGTGLGLTIASSL 588
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
312-522 |
5.13e-09 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 58.98 E-value: 5.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 312 RLTAGIAHEIRNPLGAISHAAQLLQESEEldAPDRRLTQIIQDQSKRMNLV--IENVLQLSR----RRQAEPQQLDLKEW 385
Cdd:PRK09959 714 QFLATMSHEIRTPISSIMGFLELLSGSGL--SKEQRVEAISLAYATGQSLLglIGEILDVDKiesgNYQLQPQWVDIPTL 791
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 386 LQRFVDEYpGRLRNDSQLHLQLGA---GDIQTRMDPHQLNQVLSNLVQNGLRYSAQahGRGQVWLSLAR-DPESDLPVLE 461
Cdd:PRK09959 792 VQNTCHSF-GAIAASKSIALSCSStfpDHYLVKIDPQAFKQVLSNLLSNALKFTTE--GAVKITTSLGHiDDNHAVIKMT 868
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489214700 462 IIDDGPGVPADKLNNLFEPFFTT----ESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRIT 522
Cdd:PRK09959 869 IMDSGSGLSQEEQQQLFKRYSQTsagrQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTIT 933
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
312-493 |
6.70e-09 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 58.02 E-value: 6.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 312 RLTAGIAHEIRNPLGAISHAAQLLQ----ESEELdapdrrltQIIQDQSKRMNLVIENVLQLSRrrqaepQQLDLKEWLQ 387
Cdd:PRK09470 245 RLLSDISHELRTPLTRLQLATALLRrrqgESKEL--------ERIETEAQRLDSMINDLLVLSR------NQQKNHLERE 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 388 RF-VDEYPGRLRNDS-----QLHLQLGAGDIQTRM----DPHQLNQVLSNLVQNGLRYSAQahgrgQVWLSLARDpESDL 457
Cdd:PRK09470 311 TFkANSLWSEVLEDAkfeaeQMGKSLTVSAPPGPWpingNPNALASALENIVRNALRYSHT-----KIEVAFSVD-KDGL 384
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 489214700 458 PVLeIIDDGPGVPADKLNNLFEPFFTT------ESKGTGLGL 493
Cdd:PRK09470 385 TIT-VDDDGPGVPEEEREQIFRPFYRVdeardrESGGTGLGL 425
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
317-522 |
1.21e-08 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 57.64 E-value: 1.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 317 IAHEIRNPLGAISHAAQLLqeseeLDapdrrlTQIIQDQSKRMNLV-------------IENVLQLSRRR-QAEPQQLDL 382
Cdd:PRK11091 290 ISHELRTPLNGIVGLSRIL-----LD------TELTAEQRKYLKTIhvsaitlgnifndIIDMDKMERRKlQLDNQPIDF 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 383 KEwlqrFVDEypgrLRNDSQLHLQ----------LGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQahgrGQVWLSLARD 452
Cdd:PRK11091 359 TD----FLAD----LENLSGLQAEqkglrfdlepLLPLPHKVITDGTRLRQILWNLISNAVKFTQQ----GGVTVRVRYE 426
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489214700 453 PESDLpVLEIIDDGPGVPADKLNNLFEPFF-------TTESKGTGLGLYLSRELCESNQARIdYRNREEG-GGCFRIT 522
Cdd:PRK11091 427 EGDML-TFEVEDSGIGIPEDELDKIFAMYYqvkdshgGKPATGTGIGLAVSKRLAQAMGGDI-TVTSEEGkGSCFTLT 502
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
453-493 |
7.71e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 50.84 E-value: 7.71e-08
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 489214700 453 PESDLPVLEIIDDGPGVPADKLNNLFEPFFTT--ESKGTGLGL 493
Cdd:cd16919 43 IPGNYVCLEVSDTGSGMPAEVLRRAFEPFFTTkeVGKGTGLGL 85
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
421-522 |
1.03e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 50.02 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRYsaqAHGRGQVWLSLARDPESDLPVLEIIDDGPGVPADKLNNLFEPF----FTTESKGTGLGLYLS 496
Cdd:cd16921 1 LGQVLTNLLGNAIKF---RRPRRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFqrlhSREEYEGTGVGLAIV 77
|
90 100
....*....|....*....|....*.
gi 489214700 497 RELCESNQARIDYRNREEGGGCFRIT 522
Cdd:cd16921 78 RKIIERHGGRIWLESEPGEGTTFYFT 103
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
306-516 |
1.52e-07 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 53.75 E-value: 1.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 306 KLAGLGRLTAGIAHEIRNPLGAISHAAQLLQESEElDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQ-LDLKE 384
Cdd:TIGR02938 272 RLEAIRETLSAAIHRLQGPMNLISAAISVLQRRGD-DAGNPASAAMLQQALSAGREHMEALRQVIPQSPQEIVVpVNLNQ 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 385 WLQRFVDEYPGRLRN-----DSQLHLQLGAgdiqTRMDPHQLNQVLSNLVQNGLRYSAQAHGRGQVwLSLARDPESDLPV 459
Cdd:TIGR02938 351 ILRDVITLSTPRLLAagivvDWQPAATLPA----ILGRELQLRSLFKALVDNAIEAMNIKGWKRRE-LSITTALNGDLIV 425
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 460 LEIIDDGPGVPADKLNNLFEPFFTTES---KGTGLGLYLSRELCESNQARIDYRNREEGG 516
Cdd:TIGR02938 426 VSILDSGPGIPQDLRYKVFEPFFTTKGgsrKHIGMGLSVAQEIVADHGGIIDLDDDYSEG 485
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
417-523 |
1.05e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 47.46 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 417 DPHQLNQVLSNLVQNGLRYSaqahgRGQVWLSLARDPESDLPVLEIIDDGPGVPADKLNNLFEPFFTTE----SKG-TGL 491
Cdd:cd16975 1 DTLLLSRALINIISNACQYA-----PEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDtsrrSGGhYGM 75
|
90 100 110
....*....|....*....|....*....|..
gi 489214700 492 GLYLSRELCESNQARIDYRNREEGGGCFRITF 523
Cdd:cd16975 76 GLYIAKNLVEKHGGSLIIENSQKGGAEVTVKI 107
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
419-523 |
1.08e-06 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 47.99 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 419 HQLNQVLSNLVQNGLRYSAQAHGRGQVWLSLARDPESdLpVLEIIDDGPGVPADKLNnlfEPFftTESKGTGLGLYLSRE 498
Cdd:COG2172 33 DDLVLAVSEAVTNAVRHAYGGDPDGPVEVELELDPDG-L-EIEVRDEGPGFDPEDLP---DPY--STLAEGGRGLFLIRR 105
|
90 100
....*....|....*....|....*
gi 489214700 499 LCEsnqaRIDYRnREEGGGCFRITF 523
Cdd:COG2172 106 LMD----EVEYE-SDPGGTTVRLVK 125
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
417-521 |
2.26e-06 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 46.33 E-value: 2.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 417 DPHQLNQVLSNLVQNGLRYSAQAhGRGQVWLSLARDPESdlpVLEIIDDGPGVPADKLNNLFEPF------FTTESKGTG 490
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDG-GRIRCILEKFRLNRF---LLTVSDSGPGIPPNLREEIFERFrqgdgsSTRAHGGTG 76
|
90 100 110
....*....|....*....|....*....|.
gi 489214700 491 LGLYLSRELCESNQARIDYRNREEGGGCFRI 521
Cdd:cd16925 77 LGLSIVKEFVELHGGTVTVSDAPGGGALFQV 107
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
419-509 |
3.20e-06 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 49.91 E-value: 3.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 419 HQLNQVLSNLVQNGLRYSAQAHGrGQVWLSLA-RDPESDLpvlEIIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYLSR 497
Cdd:PRK11086 432 HELITILGNLIENALEAVGGEEG-GEISVSLHyRNGWLHC---EVSDDGPGIAPDEIDAIFDKGYSTKGSNRGVGLYLVK 507
|
90
....*....|..
gi 489214700 498 ELCESNQARIDY 509
Cdd:PRK11086 508 QSVENLGGSIAV 519
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
417-501 |
9.05e-06 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 48.43 E-value: 9.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 417 DPHQLNQVLSNLVQNGLRYSAQahgrGQVWLSLARDpeSDLPVLEIIDDGPGVPADKLNNLFEPFFT------TESKGTG 490
Cdd:PRK10841 559 DPMRLQQVISNLLSNAIKFTDT----GCIVLHVRVD--GDYLSFRVRDTGVGIPAKEVVRLFDPFFQvgtgvqRNFQGTG 632
|
90
....*....|.
gi 489214700 491 LGLylsrELCE 501
Cdd:PRK10841 633 LGL----AICE 639
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
421-527 |
7.81e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 42.19 E-value: 7.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRYSAQAhgrGQVWLSLARDPESdlPVLEIIDDGPGVPADKLNNLFEPFFTTESK------GTGLGLY 494
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPS---DTITVRWSQEESG--ARLSVEDTGPGIPPEHIPRLTERFYRVDIErcrntgGTGLGLA 75
|
90 100 110
....*....|....*....|....*....|...
gi 489214700 495 LSRELCESNQARIDYRNREEGGGCFRITFAHPR 527
Cdd:cd16952 76 IVKHVMSRHDARLLIASELGKGSRFTCLFPSSR 108
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
314-507 |
1.16e-04 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 44.76 E-value: 1.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 314 TAGIAHEIRNPLgaishaAQLLQESEELDAPDR---RLTQIIQ---DQSKRMNLVIENVLQLSrrrQAEPQQL------- 380
Cdd:PRK09835 266 SADIAHEIRTPI------TNLITQTEIALSQSRsqkELEDVLYsnlEELTRMAKMVSDMLFLA---QADNNQLipekkml 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 381 DLKEWLQRFVDEYPGrLRNDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQAHgrgQVWLSLArdpESDLPVL 460
Cdd:PRK09835 337 DLADEVGKVFDFFEA-WAEERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALRYTPAGE---AITVRCQ---EVDHQVQ 409
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 489214700 461 EIIDDgPGVP--ADKLNNLFEPFFTTE------SKGTGLGLYLSRELCESNQARI 507
Cdd:PRK09835 410 LVVEN-PGTPiaPEHLPRLFDRFYRVDpsrqrkGEGSGIGLAIVKSIVVAHKGTV 463
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
428-523 |
2.57e-04 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 43.74 E-value: 2.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 428 LVQNGLRYSAQAHGRGQVWLSLARDPEsDLpVLEIIDDGPGVPADklnnlfepffTTESKGTGLGLYLSRELCESNQARI 507
Cdd:COG3920 407 LVTNALKHAFLSGEGGRIRVSWRREDG-RL-RLTVSDNGVGLPED----------VDPPARKGLGLRLIRALVRQLGGTL 474
|
90
....*....|....*.
gi 489214700 508 DYRNREegGGCFRITF 523
Cdd:COG3920 475 ELDRPE--GTRVRITF 488
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
424-523 |
2.74e-04 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 43.47 E-value: 2.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 424 VLSNLVQNGLRYSAQAH-GRGQVWLSLARDpESDLpVLEIIDDGPGVPADKLNNLFEPfFTTESKGTGLGLYLSRE---L 499
Cdd:COG2972 340 ILQPLVENAIEHGIEPKeGGGTIRISIRKE-GDRL-VITVEDNGVGMPEEKLEKLLEE-LSSKGEGRGIGLRNVRErlkL 416
|
90 100
....*....|....*....|....
gi 489214700 500 CESNQARIDYRNREEGGGCFRITF 523
Cdd:COG2972 417 YYGEEYGLEIESEPGEGTTVTIRI 440
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
402-522 |
2.92e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 40.96 E-value: 2.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 402 QLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQAHGRGqvwLSLaRDPESDLpVLEIIDDGPGVPADKLNNLFEPF 481
Cdd:cd16947 2 QVEINIPDRPIYANANTEALQRILKNLISNAIKYGSDGKFLG---MTL-REDEKHV-YIDIWDKGKGISETEKDHVFERL 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 489214700 482 FTTES------KGTGLGLYLSRELCESNQARIDYRNREEGGGCFRIT 522
Cdd:cd16947 77 YTLEDsrnsakQGNGLGLTITKRLAESMGGSIYVNSKPYEKTVFTVT 123
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
312-522 |
4.64e-04 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 43.00 E-value: 4.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 312 RLTAGIAHEIRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQlsrrrqaepQQLDLKEW------ 385
Cdd:PRK10618 452 AFLQNIGDELKQPLQSLAQLAAQLRQTSDEEQQQPELDQLAEQSDVLVRLVDNIQLL---------NMLETQDWkpeqel 522
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 386 --LQRFVDE-YPGRLRNDSQLHLQLGagdIQTRMDPHQ--------LNQVLSNLVQnglrYSAQAHGRGQVWLSLARDPE 454
Cdd:PRK10618 523 fsLQDLIDEvLPEVLPAIKRKGLQLL---IHNHLKAEQlrigdrdaLRKILLLLLN----YAITTTAYGKITLEVDQDES 595
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489214700 455 -SDLPVLEIIDDGPGVPADKLNNLFEPFFTTES-----KGTGLGLYLSRELCESNQARIDYRNREEGGGCFRIT 522
Cdd:PRK10618 596 sPDRLTIRILDTGAGVSIKELDNLHFPFLNQTQgdrygKASGLTFFLCNQLCRKLGGHLTIKSREGLGTRYSIH 669
|
|
| RhaT |
COG0697 |
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ... |
67-184 |
7.16e-04 |
|
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];
Pssm-ID: 440461 [Multi-domain] Cd Length: 290 Bit Score: 41.75 E-value: 7.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 67 ALFLPPSRQLLPIFILALTD-VLMLCGLFYAGGGVPSGIGSLL-----VVAVAIANILLRGRIGLVIAAAASLGLL--YL 138
Cdd:COG0697 56 RLPPLSRRDWLLLLLRGLLGlALAFLLFFLALQYTPAALAALLlalapLFVALLAALLLGERLSRRRWLGLLLGFAgvLL 135
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 489214700 139 TFFLSLSSPDATNHYVQAGGLGTLCFAAALVIQALVRRQEQTETLA 184
Cdd:COG0697 136 IVGPGGGGGGGSLLGDLLALLAALSWALYTVLTRRLSRRLDPLTLT 181
|
|
| HATPase_Phy-like |
cd16932 |
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana ... |
421-522 |
1.30e-03 |
|
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana Phytochrome A, B, C, D and E; This family includes the histidine kinase-like ATPase (HATPase) domains of plant red/far-red photoreceptors, the phytochromes, and includes the Arabidopsis thaliana phytochrome family phyA-phyE. Following red light absorption, biologically inactive forms of phytochromes convert to active forms, which rapidly convert back to inactive forms upon far-red light irradiation. Phytochromes can be considered as having an N-terminal photosensory region to which a bilin chromophore is bound, and a C-terminal output region, which includes the HATPase domain represented here, and is involved in dimerization and presumably contributes to relaying the light signal to downstream signaling events.
Pssm-ID: 340409 [Multi-domain] Cd Length: 113 Bit Score: 38.79 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRYSAQAHGRGQVWLSLARDPESD---LPVLE--IIDDGPGVPADKLNNLFEpffttESKGT---GLG 492
Cdd:cd16932 7 LQQVLADFLLNAVRFTPSPGGWVEIKVSPTKKQIGDgvhVIHLEfrITHPGQGLPEELVQEMFE-----ENQWTtqeGLG 81
|
90 100 110
....*....|....*....|....*....|
gi 489214700 493 LYLSRELCESNQARIDYRnREEGGGCFRIT 522
Cdd:cd16932 82 LSISRKLVKLMNGDVRYL-REAGRSYFLIT 110
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
401-495 |
3.69e-03 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 39.82 E-value: 3.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 401 SQLHlQLGAGdiqtrMDPHQLNQVLSNLVQNGLRYSAQ-AHGRGQVWLSLArdPESDLPVLEIIDDGPGVPADKLNNLFE 479
Cdd:PRK15053 419 SQLS-QLPPG-----LDSTEFAAIVGNLLDNAFEASLRsDEGNKIVELFLS--DEGDDVVIEVADQGCGVPESLRDKIFE 490
|
90
....*....|....*....
gi 489214700 480 PFFTTESKGT---GLGLYL 495
Cdd:PRK15053 491 QGVSTRADEPgehGIGLYL 509
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
421-522 |
6.28e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 36.60 E-value: 6.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 421 LNQVLSNLVQNGLRYSAQahgrgQVWLSLARDPESDLPVLEIIDDGPGVPADKLNNLFEPFF----TTESKGTGLGLYLS 496
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPE-----NTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYrgdnSRNTEGAGLGLSIA 75
|
90 100
....*....|....*....|....*.
gi 489214700 497 RELCESNQARIDYRNrEEGGGCFRIT 522
Cdd:cd16923 76 KAIIELHGGSASAEY-DDNHDLFKVR 100
|
|
| PAS |
smart00091 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
196-260 |
6.72e-03 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels.
Pssm-ID: 214512 Cd Length: 67 Bit Score: 35.45 E-value: 6.72e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489214700 196 ELNALILQRMRTGILVVDSRQAILLANQAALGLL--RQDDVQGASLGRHSPMLMHCMKQWRLNPSLR 260
Cdd:smart00091 1 ERLRAILESLPDGIFVLDLDGRILYANPAAEELLgySPEELIGKSLLELIHPEDRERVQEALQRLLS 67
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
424-515 |
8.81e-03 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 35.71 E-value: 8.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489214700 424 VLSNLVQNGLRYSAQAHGRGQVWLSLARDPESdLpVLEIIDDGPGVPADKlnnLFEPffTTESKGTGLGLYLSRELCEsn 503
Cdd:cd16936 4 AVSEAVTNAVRHAYRHDGPGPVRLELDLDPDR-L-RVEVTDSGPGFDPLR---PADP--DAGLREGGRGLALIRALMD-- 74
|
90
....*....|..
gi 489214700 504 qaRIDYRNREEG 515
Cdd:cd16936 75 --EVGYRRTPGG 84
|
|
| |
