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Conserved domains on  [gi|489190565|ref|WP_003099931|]
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MULTISPECIES: ATP-dependent zinc protease [Gammaproteobacteria]

Protein Classification

ATP-dependent zinc protease( domain architecture ID 10528944)

ATP-dependent zinc protease such as retroviral-like aspartic protease, which contains a conserved active site motif (Asp-Thr/Ser-Gly-Ser) and belongs to a family that includes both cellular and retroviral pepsin-like aspartate proteases

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Zn_protease pfam05618
Putative ATP-dependant zinc protease; Proteins in this family are annotated as being ...
 30-167 1.67e-57

Putative ATP-dependant zinc protease; Proteins in this family are annotated as being ATP-dependant zinc proteases.


:

Pssm-ID: 283308  Cd Length: 138  Bit Score: 176.57  E-value: 1.67e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489190565   30 HWGWIEQSWLMPERMQAKAKLDTGALTSSLDARNIHRYRKDGERWVRFDVvlPTADSKAPVSVTFERKVLRLIKVRGAGG 109
Cdd:pfam05618   1 VVGWIEELFLPGLKIQLKAKIDTGALTSSLSAGDIWSFERDGESWVRFKE--TRLDTKNQRGYTLEAPVLRIVKIRQSGG 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489190565  110 -SDSRPVVAMDICLGAKLLREQFSLRDRGNMNYPVLLG-RRTLEHLGAVDVSRTFTRKPT 167
Cdd:pfam05618  79 dAERRPVIKLYLCLGPKIERIEFTLTDRSLMKYPVLLGsRALRKHLAEVDPSRKYIRIKE 138
 
Name Accession Description Interval E-value
Zn_protease pfam05618
Putative ATP-dependant zinc protease; Proteins in this family are annotated as being ...
 30-167 1.67e-57

Putative ATP-dependant zinc protease; Proteins in this family are annotated as being ATP-dependant zinc proteases.


Pssm-ID: 283308  Cd Length: 138  Bit Score: 176.57  E-value: 1.67e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489190565   30 HWGWIEQSWLMPERMQAKAKLDTGALTSSLDARNIHRYRKDGERWVRFDVvlPTADSKAPVSVTFERKVLRLIKVRGAGG 109
Cdd:pfam05618   1 VVGWIEELFLPGLKIQLKAKIDTGALTSSLSAGDIWSFERDGESWVRFKE--TRLDTKNQRGYTLEAPVLRIVKIRQSGG 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489190565  110 -SDSRPVVAMDICLGAKLLREQFSLRDRGNMNYPVLLG-RRTLEHLGAVDVSRTFTRKPT 167
Cdd:pfam05618  79 dAERRPVIKLYLCLGPKIERIEFTLTDRSLMKYPVLLGsRALRKHLAEVDPSRKYIRIKE 138
COG4067 COG4067
Uncharacterized conserved protein [Function unknown];
32-168 1.42e-53

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443244  Cd Length: 150  Bit Score: 166.90  E-value: 1.42e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489190565  32 GWIEQSWLMP-ERMQAKAKLDTGALTSSLDARNIHRYRKDGERWVRFDVVLPTADSKapVSVTFERKVLRLIKVRGAGG- 109
Cdd:COG4067   14 GWREWVALPElGIPAIKAKIDTGARTSSLHAFNIEEFERDGEDWVRFTVHPPQGDTD--TEVECEAPVVRRRKIKSSGGh 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 489190565 110 SDSRPVVAMDICLGAKLLREQFSLRDRGNMNYPVLLGRRTLEHLGAVDVSRTFTRKPTC 168
Cdd:COG4067   92 AERRPVVETPLCLGGQTWEIEFTLTDRSDMNYPMLLGRTALRGRFLVDPSRSFLQGKPC 150
 
Name Accession Description Interval E-value
Zn_protease pfam05618
Putative ATP-dependant zinc protease; Proteins in this family are annotated as being ...
 30-167 1.67e-57

Putative ATP-dependant zinc protease; Proteins in this family are annotated as being ATP-dependant zinc proteases.


Pssm-ID: 283308  Cd Length: 138  Bit Score: 176.57  E-value: 1.67e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489190565   30 HWGWIEQSWLMPERMQAKAKLDTGALTSSLDARNIHRYRKDGERWVRFDVvlPTADSKAPVSVTFERKVLRLIKVRGAGG 109
Cdd:pfam05618   1 VVGWIEELFLPGLKIQLKAKIDTGALTSSLSAGDIWSFERDGESWVRFKE--TRLDTKNQRGYTLEAPVLRIVKIRQSGG 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489190565  110 -SDSRPVVAMDICLGAKLLREQFSLRDRGNMNYPVLLG-RRTLEHLGAVDVSRTFTRKPT 167
Cdd:pfam05618  79 dAERRPVIKLYLCLGPKIERIEFTLTDRSLMKYPVLLGsRALRKHLAEVDPSRKYIRIKE 138
COG4067 COG4067
Uncharacterized conserved protein [Function unknown];
32-168 1.42e-53

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443244  Cd Length: 150  Bit Score: 166.90  E-value: 1.42e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489190565  32 GWIEQSWLMP-ERMQAKAKLDTGALTSSLDARNIHRYRKDGERWVRFDVVLPTADSKapVSVTFERKVLRLIKVRGAGG- 109
Cdd:COG4067   14 GWREWVALPElGIPAIKAKIDTGARTSSLHAFNIEEFERDGEDWVRFTVHPPQGDTD--TEVECEAPVVRRRKIKSSGGh 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 489190565 110 SDSRPVVAMDICLGAKLLREQFSLRDRGNMNYPVLLGRRTLEHLGAVDVSRTFTRKPTC 168
Cdd:COG4067   92 AERRPVVETPLCLGGQTWEIEFTLTDRSDMNYPMLLGRTALRGRFLVDPSRSFLQGKPC 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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