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Conserved domains on  [gi|489185305|ref|WP_003094728|]
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MULTISPECIES: signal peptidase II [Proteobacteria]

Protein Classification

signal peptidase II( domain architecture ID 10001765)

signal peptidase II specifically catalyzes the removal of signal peptides from membrane prolipoproteins; it belongs to the peptidase family A8

EC:  3.4.23.36
Gene Ontology:  GO:0004190|GO:0006508
MEROPS:  A8
PubMed:  31214988

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 10-165 4.67e-62

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 188.39  E-value: 4.67e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  10 LPWLWITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADssgwQRWLFALIAIVVSAILVVWLK 89
Cdd:COG0597    1 LLFLLLALLVLLLDQLTKLWVVANLALGESIPVIGGFFNLTYVENTGAAFGLLAG----AGWLLIILALVVLVGLLYYLR 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489185305  90 RLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrWYFPAFNLADSAITVGAVMLALDMFRSKKSGE 165
Cdd:COG0597   77 RLKKRSKLLALALGLILGGALGNLIDRLFYGYVVDFIDFHIGG-WHWPIFNVADIAITIGVILLLLDSLFGKKKKK 151
 
Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 10-165 4.67e-62

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 188.39  E-value: 4.67e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  10 LPWLWITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADssgwQRWLFALIAIVVSAILVVWLK 89
Cdd:COG0597    1 LLFLLLALLVLLLDQLTKLWVVANLALGESIPVIGGFFNLTYVENTGAAFGLLAG----AGWLLIILALVVLVGLLYYLR 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489185305  90 RLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrWYFPAFNLADSAITVGAVMLALDMFRSKKSGE 165
Cdd:COG0597   77 RLKKRSKLLALALGLILGGALGNLIDRLFYGYVVDFIDFHIGG-WHWPIFNVADIAITIGVILLLLDSLFGKKKKK 151
Peptidase_A8 pfam01252
Signal peptidase (SPase) II;
15-159 2.81e-50

Signal peptidase (SPase) II;


Pssm-ID: 460136 [Multi-domain]  Cd Length: 140  Bit Score: 158.01  E-value: 2.81e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305   15 ITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADssgwQRWLFALIAIVVSAILVVWLKRLKKG 94
Cdd:pfam01252   1 IALLLLLLDQLTKLLIVKNLKLGEPIEVIPGFFNLTYVENTGAAFGLLAG----QRWLLIILTLVAIILLIYLLLKLKKK 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489185305   95 ETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrWYFPAFNLADSAITVGAVMLALDMFR 159
Cdd:pfam01252  77 SRLLRIALALILGGALGNLIDRLFYGYVVDFIDFHIGF-INFPVFNVADIAITVGVILLIIDLLF 140
PRK14785 PRK14785
lipoprotein signal peptidase; Provisional
 10-157 3.81e-44

lipoprotein signal peptidase; Provisional


Pssm-ID: 184820  Cd Length: 171  Bit Score: 143.42  E-value: 3.81e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  10 LPWLWITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSGWQRWLFALIAIVVSAILVVWLK 89
Cdd:PRK14785  15 LNWYLLSLVVLILDQWTKWLAETKLTFLEPVPVIEPFLNWTLAYNYGAAFSFLADAGGWQKWFFAGLALIMSLFLIVYLK 94

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489185305  90 RLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNRWYFPAFNLADSAITVGAVMLALDM 157
Cdd:PRK14785  95 KAPRQAKLLSLGLALVLGGAIGNLIDRLLHGHVIDFIHVHYADVWHYPIFNIADIGICVGVALIVIDM 162
lspA TIGR00077
lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, ...
 10-163 4.85e-33

lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 272893 [Multi-domain]  Cd Length: 166  Bit Score: 115.15  E-value: 4.85e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305   10 LPWLWITVLVFV-LDQLSKAFFQAELSMYQ-QIVVIPDLFSWTLAYNTGAAFSFLADSSGwQRWLFALIAIVVSAILVVW 87
Cdd:TIGR00077   9 LLLYWLVAILFIgFDQLSKYLVLQNFDLGEtYFVAFSGVFNITYVRNTGAAFSLLADQGG-QVYFLKGLAIAISLGLFVF 87

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489185305   88 LKRLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrWYFPAFNLADSAITVGAVMLALDMFRSKKS 163
Cdd:TIGR00077  88 LLRYKELFKITNIAFGLIFGGALGNFIDRLVRGGVVDFFDFYFGN-YHFPIFNFADSSICIGVILLLLYFFFPKRK 162
 
Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 10-165 4.67e-62

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 188.39  E-value: 4.67e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  10 LPWLWITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADssgwQRWLFALIAIVVSAILVVWLK 89
Cdd:COG0597    1 LLFLLLALLVLLLDQLTKLWVVANLALGESIPVIGGFFNLTYVENTGAAFGLLAG----AGWLLIILALVVLVGLLYYLR 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489185305  90 RLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrWYFPAFNLADSAITVGAVMLALDMFRSKKSGE 165
Cdd:COG0597   77 RLKKRSKLLALALGLILGGALGNLIDRLFYGYVVDFIDFHIGG-WHWPIFNVADIAITIGVILLLLDSLFGKKKKK 151
Peptidase_A8 pfam01252
Signal peptidase (SPase) II;
15-159 2.81e-50

Signal peptidase (SPase) II;


Pssm-ID: 460136 [Multi-domain]  Cd Length: 140  Bit Score: 158.01  E-value: 2.81e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305   15 ITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADssgwQRWLFALIAIVVSAILVVWLKRLKKG 94
Cdd:pfam01252   1 IALLLLLLDQLTKLLIVKNLKLGEPIEVIPGFFNLTYVENTGAAFGLLAG----QRWLLIILTLVAIILLIYLLLKLKKK 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489185305   95 ETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrWYFPAFNLADSAITVGAVMLALDMFR 159
Cdd:pfam01252  77 SRLLRIALALILGGALGNLIDRLFYGYVVDFIDFHIGF-INFPVFNVADIAITVGVILLIIDLLF 140
PRK14785 PRK14785
lipoprotein signal peptidase; Provisional
 10-157 3.81e-44

lipoprotein signal peptidase; Provisional


Pssm-ID: 184820  Cd Length: 171  Bit Score: 143.42  E-value: 3.81e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  10 LPWLWITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSGWQRWLFALIAIVVSAILVVWLK 89
Cdd:PRK14785  15 LNWYLLSLVVLILDQWTKWLAETKLTFLEPVPVIEPFLNWTLAYNYGAAFSFLADAGGWQKWFFAGLALIMSLFLIVYLK 94

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489185305  90 RLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNRWYFPAFNLADSAITVGAVMLALDM 157
Cdd:PRK14785  95 KAPRQAKLLSLGLALVLGGAIGNLIDRLLHGHVIDFIHVHYADVWHYPIFNIADIGICVGVALIVIDM 162
PRK14791 PRK14791
lipoprotein signal peptidase; Provisional
 12-154 1.76e-36

lipoprotein signal peptidase; Provisional


Pssm-ID: 237817 [Multi-domain]  Cd Length: 146  Bit Score: 123.13  E-value: 1.76e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  12 WLWITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADssgwQRWLFALIAIVVSAILVVWLKRL 91
Cdd:PRK14791   2 EIIIIILGIFLDQLTKIWALKNLASGGDIPVIKNFFSLTYVENRGAAFGILQN----KTLFLILITIIVILGLIYYIIKY 77

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489185305  92 KKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrWYFPAFNLADSAITVGAVMLA 154
Cdd:PRK14791  78 KPTSKLYKISLSLIISGAIGNLIDRIRYGYVVDFIDFHFKD-YYFPVFNVADILVVVGTILLA 139
lspA TIGR00077
lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, ...
 10-163 4.85e-33

lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 272893 [Multi-domain]  Cd Length: 166  Bit Score: 115.15  E-value: 4.85e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305   10 LPWLWITVLVFV-LDQLSKAFFQAELSMYQ-QIVVIPDLFSWTLAYNTGAAFSFLADSSGwQRWLFALIAIVVSAILVVW 87
Cdd:TIGR00077   9 LLLYWLVAILFIgFDQLSKYLVLQNFDLGEtYFVAFSGVFNITYVRNTGAAFSLLADQGG-QVYFLKGLAIAISLGLFVF 87

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489185305   88 LKRLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrWYFPAFNLADSAITVGAVMLALDMFRSKKS 163
Cdd:TIGR00077  88 LLRYKELFKITNIAFGLIFGGALGNFIDRLVRGGVVDFFDFYFGN-YHFPIFNFADSSICIGVILLLLYFFFPKRK 162
PRK14776 PRK14776
lipoprotein signal peptidase; Provisional
 13-167 1.33e-31

lipoprotein signal peptidase; Provisional


Pssm-ID: 173237  Cd Length: 170  Bit Score: 111.57  E-value: 1.33e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  13 LWITVLVFVLDQLSKAFFQAELSMYQQIVVIPdLFSWTLAYNTGAAFSFLADSSGWQRWLFALIAIVVSAILV-VWLKRL 91
Cdd:PRK14776  14 LSISGLLAASDQAVKWLVQQSMAYGEYVSVTP-FFNWVHLWNTGAAFSLFANGGGWQRYFFIGIAVVVSIFLIkLILENR 92

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489185305  92 KKGEtwlAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrWYFPAFNLADSAITVGAVMLALDMFRSKKSGEAA 167
Cdd:PRK14776  93 HKGE---AIAYSLILGGAMGNLIDRVFRGYVVDSFDFYWRD-WHWPAFNLADIAIVLGALLFVSSSLLGKKANTNA 164
PRK14779 PRK14779
lipoprotein signal peptidase; Provisional
 10-164 2.06e-25

lipoprotein signal peptidase; Provisional


Pssm-ID: 184818  Cd Length: 159  Bit Score: 95.16  E-value: 2.06e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  10 LPWLWITVLVFVLDQLSKaFFQAELSMYQQIVVIPdLFSWTLAYNTGAAFSFLADSSGWQRWLFALIAIVVSAILVVwLK 89
Cdd:PRK14779   6 LAYLGTFFLVLVLDLITK-YLAEKYLFDKDISVIP-FLDLVLVYNKGVAFGLLSEAPDFIRLPILLLTPIIALIITF-LY 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489185305  90 RLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWqNRWYFPAFNLADSAITVGAVMLALDMFRSKKSG 164
Cdd:PRK14779  83 ALKSNDKLSNLSMGLIGGGALGNLYDRFFLGQVRDFIDIYI-GDFHWPAFNIADASISIGIALFILYEHFFKKRK 156
PRK14772 PRK14772
lipoprotein signal peptidase; Provisional
 6-159 4.11e-24

lipoprotein signal peptidase; Provisional


Pssm-ID: 237812 [Multi-domain]  Cd Length: 190  Bit Score: 93.01  E-value: 4.11e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305   6 RFGRLPWLW--ITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSgwqrWLFALIAIVVSAI 83
Cdd:PRK14772  20 RRWRLLILFagFAVFAYVFDQLTKLWVTSTMVEGERIPVLPPLLHWYYIRNSGAAFSIGENVT----WVFSIIMAAVAVA 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  84 LVVWLKRLkkGETWLAIALALVLGGALGNLYDRMV------LGHVVDFILVHwqnrwYFPAFNLADSAITVGAVMLALDM 157
Cdd:PRK14772  96 ILVQLRKL--GSAWWALALGLLLGGALGNLTDRLFrepsfgMGHVVDFIQLP-----NFAIFNIADSAVVSGVVIICLLT 168


                 ..
gi 489185305 158 FR 159
Cdd:PRK14772 169 LR 170
PRK14773 PRK14773
lipoprotein signal peptidase; Provisional
 49-166 7.97e-24

lipoprotein signal peptidase; Provisional


Pssm-ID: 173234  Cd Length: 192  Bit Score: 92.22  E-value: 7.97e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  49 WTLAY--NTGAAFSFLAD-SSGWQRWLFALIAIVVSAILVVWLKRLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDF 125
Cdd:PRK14773  70 WRMNYveNPGAAWGLFRGhSEEFRNAFFTLVSLAAVAFILHYYRKLRQEQRYLQVALALVLGGAVGNFVDRLARGYVIDF 149

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 489185305 126 ILVHWQNR--WYFPAFNLADSAITVGAVMLALDMFRSKKSGEA 166
Cdd:PRK14773 150 IEWYWWNRpdIRWPTFNVADSLIVVGVAMLVLHPGSRKEAPRA 192
PRK14787 PRK14787
lipoprotein signal peptidase; Provisional
 15-155 2.36e-23

lipoprotein signal peptidase; Provisional


Pssm-ID: 173248  Cd Length: 159  Bit Score: 90.06  E-value: 2.36e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  15 ITVLVFVLDQLSKAFFQAEL-SMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSGwqrwLFALIAIVVSAILVVWLKRLKK 93
Cdd:PRK14787   7 LALAVIVLDQFTKKLAITFLrDGPQSITIIPDWFKLTYAENRGIAFGLEFAPPE----VLLLLTGAISAGVLWYVLRSKN 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489185305  94 GETWLAIALALVLGGALGNLYDRMVLGHVVDFILV---------HWQNRWyfPAFNLADSAITVGAVMLAL 155
Cdd:PRK14787  83 RTPLFLLAFGLILGGGIGNLIDRITSGRVVDFIYFdlyqgyifgIWVSLW--PIFNIADSAITIGACMLLL 151
PRK14770 PRK14770
lipoprotein signal peptidase; Provisional
 17-163 3.85e-22

lipoprotein signal peptidase; Provisional


Pssm-ID: 173231  Cd Length: 167  Bit Score: 87.18  E-value: 3.85e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  17 VLVFVLDQLSKAF--FQAELSMYQQIVVIPDLfSWTLAYNTGAAFSFLADSSGWQRWLFALIAIVVSAILVVWLKRLKKg 94
Cdd:PRK14770  18 VAVLLLDQASKYWilYGLDLPDRGSVPVLPFL-NFTMVWNHAVTFGMLGGLGGIGRVVFSAVSLAAVLLLGVWLTRTPR- 95

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489185305  95 eTWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrWYFPAFNLADSAITVGAVMLALDMFRSKKS 163
Cdd:PRK14770  96 -PLVAAALGAIMGGAIGNVIDRMRYGAVVDFLHAHAFG-WSWYVFNLADAAIDCGVAVLLIDSLLARRQ 162
PRK14790 PRK14790
lipoprotein signal peptidase; Provisional
 15-155 8.96e-22

lipoprotein signal peptidase; Provisional


Pssm-ID: 173251  Cd Length: 169  Bit Score: 86.07  E-value: 8.96e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  15 ITVLVFVLDQLSKAFFQAELS---MYQQIVVIPDLFSWTLAYNTGAAFSFLadsSGWQRWLFALIAIVVSAILVVWLKRL 91
Cdd:PRK14790  15 VAATILALDQASKRWILATLGpvpMTKFIPLIGEDIRLAYSHNTGIAFSLF---DGKSDILTVVALVISLGAIYLYRTQL 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489185305  92 KKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWqnrwyFPAFNLADSAITVGAVMLAL 155
Cdd:PRK14790  92 PNRRLLIQVAMGLILGGALGNVIDRIRLGYVVDFIQVGW-----FPIFNLADSAITVGAALLML 150
PRK14767 PRK14767
lipoprotein signal peptidase; Provisional
 15-155 2.50e-18

lipoprotein signal peptidase; Provisional


Pssm-ID: 237811  Cd Length: 174  Bit Score: 77.44  E-value: 2.50e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  15 ITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADssgwQRWLFALIAIVVSAILVVWLKRLKKG 94
Cdd:PRK14767  16 LFVILVILDQITKYLAVSHLADKPSFVIIPGVFELIYLENSGAAFGMLSG----KAVFFLVITVAVVIIMAFVFFKLPAT 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489185305  95 ETWLAIALALVL--GGALGNLYDRMVLGHVVDFILVHWQNrwyFPAFNLADSAITVGAVMLAL 155
Cdd:PRK14767  92 KKYNPLHIILVFivAGAAGNLIDRILNGYVVDFIYFKLIN---FPIFNVADIYVTVSTFLFII 151
PRK14789 PRK14789
lipoprotein signal peptidase; Provisional
 13-155 3.61e-18

lipoprotein signal peptidase; Provisional


Pssm-ID: 173250  Cd Length: 191  Bit Score: 77.38  E-value: 3.61e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  13 LWITVLVFVLDQLSKAFFQAELSMYQQIVVIpdLFSWT-LAY--NTGAAFSFLADSSGwqrwLFALIAIVVSAILVVWLK 89
Cdd:PRK14789   9 VLVAIPVFVIDQLSKVWLSDVLLRYNRPIPL--LFDWVqLAYheNTGVAFGLFPDQGG----VLSVGAGLVLLLLALTYQ 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489185305  90 RLKKGET-WLAIALALVLGGALGNLYDRMVLGHVVDFILVHWqnrwyFPAFNLADSAITVGAVMLAL 155
Cdd:PRK14789  83 YILPADSrWITVAVGMIFGGGLSNLVDRIRQGYVVDFIQFGW-----WPVFNLADSAITIGVAALAF 144
PRK14786 PRK14786
lipoprotein signal peptidase; Provisional
 15-169 9.76e-18

lipoprotein signal peptidase; Provisional


Pssm-ID: 173247  Cd Length: 154  Bit Score: 75.40  E-value: 9.76e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  15 ITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLadsSGWQRWLFALIAIVVSAILVVWLKRLKKG 94
Cdd:PRK14786   6 IITILTGIDQWTKYLIETQLKPIGAIPIVKDIFHLTYARNTGAAFSIL---RDKQAFLILVTTIVVGALIYYLIKILKTG 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489185305  95 ETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNrwyFPAFNLADSAITVGAVMLALDMFRSKKSGEAAHG 169
Cdd:PRK14786  83 EVAFKLSLAIIIGGALGNLIDRVRLNYVTDFLDFTLIN---YPIFNLADVFVVSGVVMLSYMLLFKGDMPKISKM 154
PRK14778 PRK14778
lipoprotein signal peptidase; Provisional
 14-165 1.50e-16

lipoprotein signal peptidase; Provisional


Pssm-ID: 173239  Cd Length: 186  Bit Score: 72.92  E-value: 1.50e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  14 WITvLVFVLDQLSKAFFQAelsMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSGWQRWLFALIAIVVSaiLVVWLKRLKK 93
Cdd:PRK14778   4 VIV-LTIVLDQLTKRIASE---IHGTFFIVPGFLRFVKATNRGVALGLFSNLSEQVLWTVLFVVVFLS--LLPYIFRFSR 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489185305  94 getWLAIALALVLGGALGNLYDRMVLGHVVDFIlvhwqNRWYFPA-FNLADSAITVGAVMLALDMFRSKKSGE 165
Cdd:PRK14778  78 ---LERMAMGFILGGALGNLLDRIRFGYVLDFL-----NLTFLPTiFNLADVFIIVGGALMILGVFRGGDNES 142
PRK14784 PRK14784
lipoprotein signal peptidase; Provisional
 21-164 1.88e-16

lipoprotein signal peptidase; Provisional


Pssm-ID: 184819 [Multi-domain]  Cd Length: 160  Bit Score: 72.19  E-value: 1.88e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  21 VLDQLSKAFFQAELSMYQQIVViPDLFSWTLAYNTGAAFSFLadsSGWQRWLFALIAIVVSAILVVWLKRLKKG--ETWL 98
Cdd:PRK14784  16 LADQLSKFIITANLTTGTSIPE-SGFFQIVHVHNTGAAFSIF---RGHIEWLIAASVLGVILAMTAFFIRKKLPflDTRP 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489185305  99 A-IALALVLGGALGNLYDRMVLGHVVDFILVHwqnrwYFPAFNLADSAITVGAVMLALDMFRSKKSG 164
Cdd:PRK14784  92 GlIALGVILAGTVGNLIDRVRLGYVTDFIRVG-----DFPTFNIADSCLTVGVIGLLLLYLVSSHVS 153
PRK14777 PRK14777
lipoprotein signal peptidase; Provisional
 10-159 9.52e-15

lipoprotein signal peptidase; Provisional


Pssm-ID: 237814 [Multi-domain]  Cd Length: 184  Bit Score: 68.34  E-value: 9.52e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  10 LPWLWITVLVfVLDQLSKAFFQAELSMYQQ-IVVIPDLFSWTLAYNTGAAFSFLADSSgwqrWLFALIAIVVSAILVVWL 88
Cdd:PRK14777  28 APLVLATLLI-VLDQALKAWALANLQLGAPaIPVLPGVLDWVLTFNTGAAWSLFSGSA----LPLALMRLLVGLGLLVYL 102

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489185305  89 KRLKKGeTWLAIALALVLGGALGNLYDRMVLGHVVDFILVHWQNRWY-------FPAFNLADSAITVGAVMLALDMFR 159
Cdd:PRK14777 103 LRRPQP-RFLTVVLSLIAAGAIGNAIDGLRFGRVTDMLHSPALSAVTralgqgdFPIFNLADMCVVGGTLLLLFASFQ 179
PRK14771 PRK14771
lipoprotein signal peptidase; Provisional
 15-130 1.79e-14

lipoprotein signal peptidase; Provisional


Pssm-ID: 184816  Cd Length: 165  Bit Score: 67.15  E-value: 1.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  15 ITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSgwqrWLFALIAIVVSAILVVWLKRlKKG 94
Cdd:PRK14771  18 IAIAALIVDQLTKAWAQAALSDGQTIRVIPGLLSLTLVRNPGASLGMGSGAT----WVISLLAIVACVALVVAAVR-TIS 92

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 489185305  95 ETWlAIALALVLGGALGNLYDRMVL------GHVVDFILVHW 130
Cdd:PRK14771  93 MKW-TVALALAFAGALGNLIDRVMYaqgflnGKVVDFLNYGW 133
PRK14775 PRK14775
lipoprotein signal peptidase; Provisional
 17-161 4.74e-14

lipoprotein signal peptidase; Provisional


Pssm-ID: 237813  Cd Length: 170  Bit Score: 66.07  E-value: 4.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  17 VLVFVLDQLSKAFFQAELSMYQQIVVIpDLFSWTLAYNTGAAFS-FLADSSGwqRWLFALIAIVVSAILVVWLKRLKKGE 95
Cdd:PRK14775  12 VLVFALDQVSKAYAIDWYSQSGATEVF-KFCSLVEVWNRGISFGmFGALESS--NLIFTYVSLGVILMLFVLFVQSKCNK 88

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489185305  96 TwlAIALALVLGGALGNLYDRMVLGHVVDFILVHwQNRWYFPAFNLADSAITVGA-VMLALD-MFRSK 161
Cdd:PRK14775  89 S--TICMGVVIGGALGNLADRLRFGAVYDFISLH-AGEFHWPAFNFADVCVTCGViCFLCLEvMYHAK 153
PRK14781 PRK14781
lipoprotein signal peptidase; Provisional
 31-165 3.36e-13

lipoprotein signal peptidase; Provisional


Pssm-ID: 237815  Cd Length: 153  Bit Score: 63.29  E-value: 3.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  31 QAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSGWqrwlfALIAI--VVSAILVVWLKRLKKGETWLAIALA-LVLG 107
Cdd:PRK14781  23 QAEAGLSRGEVIDLGLINIRLLYNTGVAFSLGAGLPTW-----FVIAGtgLIIAALLWYLTSSAPKMSRLSRAGAaLLLG 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489185305 108 GALGNLYDRMVLGHVVDFILVHWqnrwyFPAFNLADSAITVGAVMLALDMFRSKKSGE 165
Cdd:PRK14781  98 GAVGNFIDRLDGRGVVDYLHSGW-----FPTFNLADVFVTTGVALLVLGMLRPPKDPE 150
PRK14769 PRK14769
lipoprotein signal peptidase; Provisional
 51-167 2.62e-10

lipoprotein signal peptidase; Provisional


Pssm-ID: 173230  Cd Length: 156  Bit Score: 55.70  E-value: 2.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  51 LAYNTGAAFSfLADSSGwQRWLFALIAIVVSAILVVWLKRLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFILVHW 130
Cdd:PRK14769  44 LAFNSGVAFS-MGDTLP-VGVIVAVTAVIVVALAVYAWRRAPTAGWVERIAGGAVIGGALANVVDRARDGLVTDYLHTGW 121

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 489185305 131 qnrwyFPAFNLADSAITVGAVMLALDMFRSKKSGEAA 167
Cdd:PRK14769 122 -----WPTFNLADTFLVTGFAVIALLHARPERTADTA 153
PRK14774 PRK14774
lipoprotein signal peptidase; Provisional
 19-169 5.07e-10

lipoprotein signal peptidase; Provisional


Pssm-ID: 173235  Cd Length: 185  Bit Score: 55.41  E-value: 5.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  19 VFVLDQLSK--AFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSGWQRWLFALIAIVVSAILVVWLKRlkKGET 96
Cdd:PRK14774  11 VFVLDQLTKwlVVWGLDLANRGAIDLVAPWLTFRMAWNRGINFGIGSSDQEIVRWGLVIVSLAISAWVWRWVWR--STPT 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489185305  97 WLA-IALALVLGGALGNLYDRMVLGHVVDFILVHWQNRWYFPAFNLADSAITVGAVMLALDMFRSKKSGEAAHG 169
Cdd:PRK14774  89 RLArISGGLLIGGALGNVVDRVLYGAVADFLNMSCCGIENPYAFNVADIAIFAGAFGLVLFTRETKPEPEKPKG 162
PRK14768 PRK14768
lipoprotein signal peptidase; Provisional
 12-155 1.21e-09

lipoprotein signal peptidase; Provisional


Pssm-ID: 173229  Cd Length: 148  Bit Score: 53.76  E-value: 1.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  12 WLWITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADSsgwqRWLFALIAIVVSAILVVWLKRl 91
Cdd:PRK14768   3 YILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVENRGAAFGLLQNN----QWIFIIVALLATVFGLYYLNT- 77

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489185305  92 KKGETWLAIALALVLGGALGNLYDRMVLGHVVDFIlvHWQNRWYFpAFNLADSAITVGAVMLAL 155
Cdd:PRK14768  78 RKVHIFGRLGIILIISGALGNLIDRVRLGFVVDYF--DFRVIWEY-VFNVADVFVVVGTVFLCI 138
PRK14788 PRK14788
lipoprotein signal peptidase; Provisional
 15-161 6.86e-08

lipoprotein signal peptidase; Provisional


Pssm-ID: 237816  Cd Length: 200  Bit Score: 49.96  E-value: 6.86e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  15 ITVLVFVLDQLSKAFFQAELSMyQQIVVIPDLFSWTLAYNTGAAFSF-LADSSGwqRWLFALIAIVVSAILVVWLKRL-- 91
Cdd:PRK14788   7 IILLVLLIDQISKIYVKTHFVL-GQSVLVFDWFKIHFVENPGMAFGMeLGGEYG--KLFLTLFRIVAVGGIGYYLWKLvk 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  92 KKGETWLAIALALVLGGALGNLYDRMVLG---------------------------HVVDFILVH-WQNRW--------- 134
Cdd:PRK14788  84 KNSSKGLIICISLILAGAIGNIIDSVFYGvifdngsygqiatffpegggystwfhgKVVDMFYFPiIDGYLpewvpfwgg 163

                        170       180       190
                 ....*....|....*....|....*....|..
gi 489185305 135 -YF----PAFNLADSAITVGAVMLALdmFRSK 161
Cdd:PRK14788 164 eHFvffkPVFNIADSAISIGVILLLL--FNKK 193
PRK14783 PRK14783
lipoprotein signal peptidase; Provisional
 12-157 4.04e-07

lipoprotein signal peptidase; Provisional


Pssm-ID: 173244  Cd Length: 182  Bit Score: 47.55  E-value: 4.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  12 WLWITVLVFVLDQLSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSgwqrwLFALIAIVVSAILVVWLkRL 91
Cdd:PRK14783  16 YLGVIFLGIFLDLVTKFLVILYFYPHRYLEVLGSFFRMTLTFNTGFVFGAFQDNA-----IPSLIATGFAIVFLIGY-RW 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489185305  92 KKGETWLAIALALVLGGALGNLYDRMVLG------------------HVVDFILVHWQN-----RWyfPAFNLADSAITV 148
Cdd:PRK14783  90 KNSDLGNPWGWNLVMAGAFGNFLDKFFVKipgtgfrfgfqpnkgeyiGVVDFLDFDWPDfllfsRW--PAFNVADSCVTI 167


                 ....*....
gi 489185305 149 GAVMLALDM 157
Cdd:PRK14783 168 GLTILIFTM 176
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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