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Conserved domains on  [gi|489183905|ref|WP_003093343|]
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MULTISPECIES: transcriptional regulator FeaR [Pseudomonas]

Protein Classification

transcriptional regulator FeaR( domain architecture ID 11484456)

HTH-type transcriptional regulator FeaR is a positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 2-314 4.27e-156

DNA-binding transcriptional activator FeaR; Provisional


:

Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 438.31  E-value: 4.27e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905   2 HTLSSAHNSFEAWNQALRQVCGRFESQPALNRtlFIGDISRQDLGGLELAQIRTNAGRIARQATHADHDDDRHCFLVVQR 81
Cdd:PRK09685   1 HTNPSADNEFQQWLSQINQVCGRFDGRPLTNR--FIGELSTHDAGGLKLSTVTTNAVNLSRTWQEIKHSDDAHFFTVFQL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905  82 SGHAQLRQGGDSIELAPGEMALMDSAGGCEIIPHGLIEHTSFHLSRDQVCRHLPPSQRA-FGKLSPNCASGRLLGLLVQQ 160
Cdd:PRK09685  79 SGHAIIEQDDRQVQLAAGDITLIDASRPCSIYPQGLSEQISLLLPRELVEQYFPGQKPAcAGRLSASLPMVQLSHRLLQQ 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 161 VCAGELQPWavaDEGGALQEALIALLGPALQHAGEELEGPLAGLYgyslrrHAERLIEQSLQEPRLSPDMLAGRLRISVR 240
Cdd:PRK09685 159 SMNGPALSE---TESEALLEALIALLRPALHQRESVQPRRERQFQ------KVVALIDQSIQEEILRPEWIAGELGISVR 229

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489183905 241 QLYRLFEEQGDSVCRYILRQRLSRSAADLgNPRLRGESITSIAFKWGFSDSAHFSRAFKKQFEVSPKDYRAGAL 314
Cdd:PRK09685 230 SLYRLFAEQGLVVAQYIRNRRLDRCADDL-RPAADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRRKFR 302
 
Name Accession Description Interval E-value
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 2-314 4.27e-156

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 438.31  E-value: 4.27e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905   2 HTLSSAHNSFEAWNQALRQVCGRFESQPALNRtlFIGDISRQDLGGLELAQIRTNAGRIARQATHADHDDDRHCFLVVQR 81
Cdd:PRK09685   1 HTNPSADNEFQQWLSQINQVCGRFDGRPLTNR--FIGELSTHDAGGLKLSTVTTNAVNLSRTWQEIKHSDDAHFFTVFQL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905  82 SGHAQLRQGGDSIELAPGEMALMDSAGGCEIIPHGLIEHTSFHLSRDQVCRHLPPSQRA-FGKLSPNCASGRLLGLLVQQ 160
Cdd:PRK09685  79 SGHAIIEQDDRQVQLAAGDITLIDASRPCSIYPQGLSEQISLLLPRELVEQYFPGQKPAcAGRLSASLPMVQLSHRLLQQ 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 161 VCAGELQPWavaDEGGALQEALIALLGPALQHAGEELEGPLAGLYgyslrrHAERLIEQSLQEPRLSPDMLAGRLRISVR 240
Cdd:PRK09685 159 SMNGPALSE---TESEALLEALIALLRPALHQRESVQPRRERQFQ------KVVALIDQSIQEEILRPEWIAGELGISVR 229

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489183905 241 QLYRLFEEQGDSVCRYILRQRLSRSAADLgNPRLRGESITSIAFKWGFSDSAHFSRAFKKQFEVSPKDYRAGAL 314
Cdd:PRK09685 230 SLYRLFAEQGLVVAQYIRNRRLDRCADDL-RPAADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRRKFR 302
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
225-310 3.16e-24

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 93.77  E-value: 3.16e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905   225 RLSPDMLAGRLRISVRQLYRLF-EEQGDSVCRYILRQRLSRSAADLgnpRLRGESITSIAFKWGFSDSAHFSRAFKKQFE 303
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFkKETGTTPKQYLRDRRLERARRLL---RDTDLSVTEIALRVGFSSQSYFSRAFKKLFG 77


                   ....*..
gi 489183905   304 VSPKDYR 310
Cdd:smart00342  78 VTPSEYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
100-316 1.95e-19

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 85.99  E-value: 1.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 100 EMALMDSAGGCEIIPHGLIEHTSFHLSRDQVCRHLPPSQRAFGKLSPNCASGRLLGLLVQQVCAGELQPWAVADEGGALQ 179
Cdd:COG2207   43 LLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 180 EALIALLGPALQHAGEELEGPLAGLYGYSLRRHAERLIEQSLQEPRLSPDMLAGRLRISVRQLYRLFEEQ-GDSVCRYIL 258
Cdd:COG2207  123 LLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEEtGTSPKQYLR 202

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489183905 259 RQRLSRSAADLGNPRLrgeSITSIAFKWGFSDSAHFSRAFKKQFEVSPKDYRAGALPA 316
Cdd:COG2207  203 ELRLERAKRLLAETDL---SISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRAR 257
HTH_18 pfam12833
Helix-turn-helix domain;
231-311 1.68e-18

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 78.40  E-value: 1.68e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905  231 LAGRLRISVRQLYRLFEEQ-GDSVCRYILRQRLSRSAADLgnPRLRGESITSIAFKWGFSDSAHFSRAFKKQFEVSPKDY 309
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLL--LEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEY 78


                  ..
gi 489183905  310 RA 311
Cdd:pfam12833  79 RR 80
adjacent_YSIRK TIGR04094
YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only ...
 215-310 4.84e-09

YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only one protein with the YSIRK variant form of signal peptide (TIGR01168) were examined for conserved genes near that one tagged protein. This protein is found adjacent to at various classes of repetitive or low-complexity YSIRK proteins (whether unique in genome or not), in a range of species (Enterococcus faecalis X98, Ruminococcus torques, Coprobacillus sp. D7, Lysinibacillus fusiformis ZC1, Streptococcus equi subsp. equi 4047, etc). The affliated YSIRK proteins include Streptococcal protective antigen (see ) and proteins with the Rib/alpha/Esp surface antigen repeat (see TIGR02331). The last quarter of this protein has an AraC family helix-turn-helix (HTH)transcriptional regulator domain.


Pssm-ID: 274977 [Multi-domain]  Cd Length: 383  Bit Score: 56.99  E-value: 4.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905  215 RLIEQSLQEPRLSPDmLAGRLRISVRQLYRLF-EEQGDSVCRYILRQRLSRSAADLGNprlrGESITSIAFKWGFSDSAH 293
Cdd:TIGR04094 292 QYINLNLYDPLKVEE-IAKQFFMSESKLRKLFkKEMGISIQEYISKRKIEEAKYLLRS----QIPVSEVSNELGFYDLSH 366

                          90
                  ....*....|....*..
gi 489183905  294 FSRAFKKQFEVSPKDYR 310
Cdd:TIGR04094 367 FSRTFKKHTGVSPKQYQ 383
 
Name Accession Description Interval E-value
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 2-314 4.27e-156

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 438.31  E-value: 4.27e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905   2 HTLSSAHNSFEAWNQALRQVCGRFESQPALNRtlFIGDISRQDLGGLELAQIRTNAGRIARQATHADHDDDRHCFLVVQR 81
Cdd:PRK09685   1 HTNPSADNEFQQWLSQINQVCGRFDGRPLTNR--FIGELSTHDAGGLKLSTVTTNAVNLSRTWQEIKHSDDAHFFTVFQL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905  82 SGHAQLRQGGDSIELAPGEMALMDSAGGCEIIPHGLIEHTSFHLSRDQVCRHLPPSQRA-FGKLSPNCASGRLLGLLVQQ 160
Cdd:PRK09685  79 SGHAIIEQDDRQVQLAAGDITLIDASRPCSIYPQGLSEQISLLLPRELVEQYFPGQKPAcAGRLSASLPMVQLSHRLLQQ 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 161 VCAGELQPWavaDEGGALQEALIALLGPALQHAGEELEGPLAGLYgyslrrHAERLIEQSLQEPRLSPDMLAGRLRISVR 240
Cdd:PRK09685 159 SMNGPALSE---TESEALLEALIALLRPALHQRESVQPRRERQFQ------KVVALIDQSIQEEILRPEWIAGELGISVR 229

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489183905 241 QLYRLFEEQGDSVCRYILRQRLSRSAADLgNPRLRGESITSIAFKWGFSDSAHFSRAFKKQFEVSPKDYRAGAL 314
Cdd:PRK09685 230 SLYRLFAEQGLVVAQYIRNRRLDRCADDL-RPAADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRRKFR 302
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
225-310 3.16e-24

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 93.77  E-value: 3.16e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905   225 RLSPDMLAGRLRISVRQLYRLF-EEQGDSVCRYILRQRLSRSAADLgnpRLRGESITSIAFKWGFSDSAHFSRAFKKQFE 303
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFkKETGTTPKQYLRDRRLERARRLL---RDTDLSVTEIALRVGFSSQSYFSRAFKKLFG 77


                   ....*..
gi 489183905   304 VSPKDYR 310
Cdd:smart00342  78 VTPSEYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
100-316 1.95e-19

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 85.99  E-value: 1.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 100 EMALMDSAGGCEIIPHGLIEHTSFHLSRDQVCRHLPPSQRAFGKLSPNCASGRLLGLLVQQVCAGELQPWAVADEGGALQ 179
Cdd:COG2207   43 LLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 180 EALIALLGPALQHAGEELEGPLAGLYGYSLRRHAERLIEQSLQEPRLSPDMLAGRLRISVRQLYRLFEEQ-GDSVCRYIL 258
Cdd:COG2207  123 LLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEEtGTSPKQYLR 202

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489183905 259 RQRLSRSAADLGNPRLrgeSITSIAFKWGFSDSAHFSRAFKKQFEVSPKDYRAGALPA 316
Cdd:COG2207  203 ELRLERAKRLLAETDL---SISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRAR 257
HTH_18 pfam12833
Helix-turn-helix domain;
231-311 1.68e-18

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 78.40  E-value: 1.68e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905  231 LAGRLRISVRQLYRLFEEQ-GDSVCRYILRQRLSRSAADLgnPRLRGESITSIAFKWGFSDSAHFSRAFKKQFEVSPKDY 309
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLL--LEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEY 78


                  ..
gi 489183905  310 RA 311
Cdd:pfam12833  79 RR 80
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 211-311 2.80e-18

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 83.67  E-value: 2.80e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 211 RHAERLIEQSLQEPrLSPDMLAGRLRISVRQLYRLFEEQ-GDSVCRYILRQRLSRSAADLGNPRLrgeSITSIAFKWGFS 289
Cdd:COG4977  213 ARAQAWMEANLEEP-LSVDELARRAGMSPRTLERRFRAAtGTTPARYLQRLRLERARRLLETTDL---SIEEIAAACGFG 288

                         90       100
                 ....*....|....*....|..
gi 489183905 290 DSAHFSRAFKKQFEVSPKDYRA 311
Cdd:COG4977  289 SASHFRRAFRRRFGVSPSAYRR 310
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
231-314 1.12e-10

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 61.23  E-value: 1.12e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 231 LAGRLRISVRQLYRLFEEQ-GDSVCRYILRQRLSRSAADLgnpRLRGESITSIAFKWGFSDSAHFSRAFKKQFEVSPKDY 309
Cdd:PRK13503 193 LADQFSLSLRTLHRQLKQQtGLTPQRYLNRLRLLKARHLL---RHSDASVTDIAYRCGFGDSNHFSTLFRREFSWSPRDI 269


                 ....*
gi 489183905 310 RAGAL 314
Cdd:PRK13503 270 RQGRD 274
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 211-316 1.07e-09

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 58.91  E-value: 1.07e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 211 RHAERLIEQSLQEpRLSPDMLAGRLRISVRQLYRLFEEQ-GDSVCRYILRQRLSRSAADLGnprlRGESITSIAFKWGFS 289
Cdd:COG2169   87 ARACRLIEAGAED-RPSLEDLAARLGLSPRHLRRLFKAHtGVTPKAYARARRLLRARQLLQ----TGLSVTDAAYAAGFG 161

                         90       100
                 ....*....|....*....|....*..
gi 489183905 290 DSAHFSRAFKKQFEVSPKDYRAGALPA 316
Cdd:COG2169  162 SLSRFYEAFKKLLGMTPSAYRRGGAGA 188
adjacent_YSIRK TIGR04094
YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only ...
 215-310 4.84e-09

YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only one protein with the YSIRK variant form of signal peptide (TIGR01168) were examined for conserved genes near that one tagged protein. This protein is found adjacent to at various classes of repetitive or low-complexity YSIRK proteins (whether unique in genome or not), in a range of species (Enterococcus faecalis X98, Ruminococcus torques, Coprobacillus sp. D7, Lysinibacillus fusiformis ZC1, Streptococcus equi subsp. equi 4047, etc). The affliated YSIRK proteins include Streptococcal protective antigen (see ) and proteins with the Rib/alpha/Esp surface antigen repeat (see TIGR02331). The last quarter of this protein has an AraC family helix-turn-helix (HTH)transcriptional regulator domain.


Pssm-ID: 274977 [Multi-domain]  Cd Length: 383  Bit Score: 56.99  E-value: 4.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905  215 RLIEQSLQEPRLSPDmLAGRLRISVRQLYRLF-EEQGDSVCRYILRQRLSRSAADLGNprlrGESITSIAFKWGFSDSAH 293
Cdd:TIGR04094 292 QYINLNLYDPLKVEE-IAKQFFMSESKLRKLFkKEMGISIQEYISKRKIEEAKYLLRS----QIPVSEVSNELGFYDLSH 366

                          90
                  ....*....|....*..
gi 489183905  294 FSRAFKKQFEVSPKDYR 310
Cdd:TIGR04094 367 FSRTFKKHTGVSPKQYQ 383
PRK15121 PRK15121
MDR efflux pump AcrAB transcriptional activator RobA;
217-310 5.58e-09

MDR efflux pump AcrAB transcriptional activator RobA;


Pssm-ID: 185076 [Multi-domain]  Cd Length: 289  Bit Score: 56.17  E-value: 5.58e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 217 IEQSLQEPrLSPDMLAGRLRISVRQLYRLFEE-QGDSVCRYILRQRLSRSAADLgnpRLRGESITSIAFKWGFSDSAHFS 295
Cdd:PRK15121  14 LEGHLDQP-LSLDNVAAKAGYSKWHLQRMFKDvTGHAIGAYIRARRLSKAAVAL---RLTSRPILDIALQYRFDSQQTFT 89

                         90
                 ....*....|....*
gi 489183905 296 RAFKKQFEVSPKDYR 310
Cdd:PRK15121  90 RAFKKQFAQTPALYR 104
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
226-316 2.25e-08

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 54.21  E-value: 2.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 226 LSPDMLAGRLRISVRQLYRLFEEQ-GDSVCRYILRQRLSRSAADLGNPRlrgESITSIAFKWGFSDSAHFSRAFKKQFEV 304
Cdd:PRK10572 200 FDIESVAQHVCLSPSRLAHLFRQQlGISVLRWREDQRISRAKLLLQTTR---MPIATIGRNVGYDDQLYFSRVFKKCTGA 276

                         90
                 ....*....|..
gi 489183905 305 SPKDYRAGALPA 316
Cdd:PRK10572 277 SPSEFRARCEEK 288
PRK11511 PRK11511
MDR efflux pump AcrAB transcriptional activator MarA;
217-316 1.29e-07

MDR efflux pump AcrAB transcriptional activator MarA;


Pssm-ID: 236920 [Multi-domain]  Cd Length: 127  Bit Score: 49.72  E-value: 1.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 217 IEQSLQEPrLSPDMLAGRLRISVRQLYRLFE-EQGDSVCRYILRQRLSRSAADLgnpRLRGESITSIAFKWGFSDSAHFS 295
Cdd:PRK11511  18 IEDNLESP-LSLEKVSERSGYSKWHLQRMFKkETGHSLGQYIRSRKMTEIAQKL---KESNEPILYLAERYGFESQQTLT 93

                         90       100
                 ....*....|....*....|.
gi 489183905 296 RAFKKQFEVSPKDYRAGALPA 316
Cdd:PRK11511  94 RTFKNYFDVPPHKYRMTNMQG 114
AraC_binding_2 pfam14525
AraC-binding-like domain; This domain is related to the AraC ligand binding domain pfam02311.
 14-190 3.10e-07

AraC-binding-like domain; This domain is related to the AraC ligand binding domain pfam02311.


Pssm-ID: 434015  Cd Length: 173  Bit Score: 49.61  E-value: 3.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905   14 WNQALRQVCGRFESQPaLNRTLFIGDISRQDLGGLELAQIRTNAGRIARQathadHDDDRHCFLVVQRSGHAQLRQGGDS 93
Cdd:pfam14525   1 WREAVSRAFGPHRLRP-LGPDRFDARLRGVRLGGLSLGRLRYGAAVHIRP-----PELDDFYLLQLPLSGSAEIEQGGRE 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905   94 IELAPGEMALMDSAGGCEIIPHGLIEHTSFHLSRDQVCRHLPPSQRAFG-KLSPNCASGRLLGLLVQQVCAGELQPWAVA 172
Cdd:pfam14525  75 VVLGPGDAVLLDPGRPYRLRWSEDCEQLVLRIPLRALLGRPLRRPLRFApRLDLDSGLGALWLRLLRLLAAELAALGPAL 154

                         170
                  ....*....|....*...
gi 489183905  173 DEGGALQEALIALLGPAL 190
Cdd:pfam14525 155 ASSPLVAAQLEELLASLL 172
ftrA PRK09393
transcriptional activator FtrA; Provisional
 217-311 4.66e-07

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 50.73  E-value: 4.66e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 217 IEQSLQEPrLSPDMLAGRLRISVRQLYRLFEE-QGDSVCRYILRQRLSRSAADLGNPRLrgeSITSIAFKWGFSDSAHFS 295
Cdd:PRK09393 227 MRAHLAEP-HTVASLAARAAMSPRTFLRRFEAaTGMTPAEWLLRERLARARDLLESSAL---SIDQIAERAGFGSEESLR 302

                         90
                 ....*....|....*.
gi 489183905 296 RAFKKQFEVSPKDYRA 311
Cdd:PRK09393 303 HHFRRRAATSPAAYRK 318
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 275-310 6.20e-07

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 45.22  E-value: 6.20e-07
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 489183905  275 RGESITSIAFKWGFSdSAHFSRAFKKQFEVSPKDYR 310
Cdd:pfam00165   7 TNLTIADIADELGFS-RSYFSRLFKKYTGVTPSQYR 41
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
217-310 8.57e-07

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 46.84  E-value: 8.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 217 IEQSLQEPrLSPDMLAGRLRISVRQLYRLFEE-QGDSVCRYILRQRLSRSAADLgnpRLRGESITSIAFKWGFSDSAHFS 295
Cdd:PRK10219  14 IDEHIDQP-LNIDVVAKKSGYSKWYLQRMFRTvTHQTLGDYIRQRRLLLAAVEL---RTTERPIFDIAMDLGYVSQQTFS 89

                         90
                 ....*....|....*
gi 489183905 296 RAFKKQFEVSPKDYR 310
Cdd:PRK10219  90 RVFRRQFDRTPSDYR 104
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
236-310 1.32e-03

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 39.89  E-value: 1.32e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489183905 236 RISVRQLYRLFEEQ-GDSVCRYILRQRLSRSAADLgnpRLRGESITSIAFKWGFSDSAHFSRAFKKQFEVSPKDYR 310
Cdd:PRK13501 203 QLVERSLKQLFRQQtGMSISHYLRQIRLCHAKCLL---RGSEHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYR 275
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 229-309 1.51e-03

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 39.59  E-value: 1.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 229 DMLAGRLRISVRQLYRLFEEQGDSVCRYILRQRLSRSAADLgnpRLRGESITSIAFKWGFSDSAHFSRAFKKQFEVSPKD 308
Cdd:PRK15185 226 TDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAAKLL---RIGNHNVNAVALKCGYDSTSYFIQCFKKYFKTTPST 302


                 .
gi 489183905 309 Y 309
Cdd:PRK15185 303 F 303
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 231-311 2.90e-03

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 38.89  E-value: 2.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489183905 231 LAGRLRISVRQLYRLFEEQGDSVCRYILRQRLSRSAADLGNPRLrgeSITSIAFKWGFSDSAHFSRAFKKQFEVSPKDYR 310
Cdd:PRK15186 203 ISDSLYMSCSTLKRKLKQENTSFSEVYLNARMNKATKLLRNSEY---NITRVAYMCGYDSASYFTCVFKKHFKTTPSEFL 279


                 .
gi 489183905 311 A 311
Cdd:PRK15186 280 A 280
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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