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Conserved domains on  [gi|489176414|ref|WP_003085936|]
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MULTISPECIES: ABC transporter permease [Pseudomonas]

Protein Classification

ABC transporter permease( domain architecture ID 11467922)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter, which may be involved in the transport of one or more from a variety of substrates such as nopaline and octopine

Gene Ontology:  GO:0140359|GO:0042626|GO:0043190|GO:0016020
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 3-231 2.36e-114

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 326.28  E-value: 2.36e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   3 FDFSVIWDSLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFD 82
Cdd:COG4160    1 MDLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYGLGQFE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  83 AVRESALWPWLSNASFCACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEV 162
Cdd:COG4160   81 WVRESWLWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALPAYSNEV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489176414 163 IMMLQTTSLASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERRWLAYLAPRK 231
Cdd:COG4160  161 ILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLLRHLRPRR 229
 
Name Accession Description Interval E-value
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 3-231 2.36e-114

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 326.28  E-value: 2.36e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   3 FDFSVIWDSLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFD 82
Cdd:COG4160    1 MDLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYGLGQFE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  83 AVRESALWPWLSNASFCACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEV 162
Cdd:COG4160   81 WVRESWLWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALPAYSNEV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489176414 163 IMMLQTTSLASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERRWLAYLAPRK 231
Cdd:COG4160  161 ILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLLRHLRPRR 229
PRK15069 PRK15069
histidine ABC transporter permease HisM;
16-229 7.67e-80

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 239.18  E-value: 7.67e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  16 FDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFDAVRESALW-PWLS 94
Cdd:PRK15069  20 FTGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYTGMYSLEIVRGTDLLdAFFR 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  95 NASFCACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEVIMMLQTTSLASI 174
Cdd:PRK15069 100 SGLNCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTLAFT 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489176414 175 VTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERRWLAYLAP 229
Cdd:PRK15069 180 ATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERRWLAHLKP 234
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 3-222 8.55e-30

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 110.33  E-value: 8.55e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414    3 FDFSVIWDSLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFd 82
Cdd:TIGR03003   1 WDWEFVRQILPTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDI- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   83 AVRESALwpwlsnasFCACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEV 162
Cdd:TIGR03003  80 GIRLPAL--------VAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYL 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  163 IMMLQTTSLASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERR 222
Cdd:TIGR03003 152 VAMFKETPVLSAITVLELMNQAKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEAR 211
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 37-213 2.12e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 68.84  E-value: 2.12e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  37 AVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFdavresALWPWLSNASFCACLAFAINTSAYTAEIL 116
Cdd:cd06261   19 GLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVL------LGWGILPGLGLPALILALLLIAPFARLIR 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414 117 AGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEVIMMLQTTSLASIVTLVDITGAARTVYSQYYLPFE 196
Cdd:cd06261   93 RAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGLLLIFAILFP 172

                        170
                 ....*....|....*..
gi 489176414 197 AFITAGLFYLCLTFILV 213
Cdd:cd06261  173 GDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 58-222 1.12e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 53.07  E-value: 1.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   58 YTYVIRGTPMLVQLFLIYYGLaqFDAVRESALWPWLsnasfcacLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMS 137
Cdd:pfam00528  23 LIDLLQALPSFVLAILLVVIA--ILSILGHGILPAI--------ILALLGWAGYARLIRRAALRSLPSDLVEAARALGAS 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  138 RLKMYRRILLPSALRRALPQYSNEVIMMLQTTSLASIVTLVDITGAARTV---YSQYYLPFEAFITAGLFYLCLTFILVR 214
Cdd:pfam00528  93 RWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEailGYDYPEIQGPVLAAALILLLLNLLVDI 172


                  ....*...
gi 489176414  215 LFKLAERR 222
Cdd:pfam00528 173 LQRLLDPR 180
 
Name Accession Description Interval E-value
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 3-231 2.36e-114

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 326.28  E-value: 2.36e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   3 FDFSVIWDSLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFD 82
Cdd:COG4160    1 MDLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYGLGQFE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  83 AVRESALWPWLSNASFCACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEV 162
Cdd:COG4160   81 WVRESWLWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALPAYSNEV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489176414 163 IMMLQTTSLASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERRWLAYLAPRK 231
Cdd:COG4160  161 ILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLLRHLRPRR 229
PRK15069 PRK15069
histidine ABC transporter permease HisM;
16-229 7.67e-80

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 239.18  E-value: 7.67e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  16 FDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFDAVRESALW-PWLS 94
Cdd:PRK15069  20 FTGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYTGMYSLEIVRGTDLLdAFFR 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  95 NASFCACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEVIMMLQTTSLASI 174
Cdd:PRK15069 100 SGLNCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTLAFT 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489176414 175 VTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERRWLAYLAP 229
Cdd:PRK15069 180 ATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERRWLAHLKP 234
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 1-223 5.71e-68

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 208.39  E-value: 5.71e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   1 MIFDFSVIWDSLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQ 80
Cdd:COG0765    1 MFFDFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  81 FDaVRESALWpwlsnasfCACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSN 160
Cdd:COG0765   81 LG-IDLSPFV--------AAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGN 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489176414 161 EVIMMLQTTSLASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERRW 223
Cdd:COG0765  152 EFISLLKDTSLVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRL 214
artM PRK11122
arginine ABC transporter permease ArtM;
47-226 1.51e-52

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 168.98  E-value: 1.51e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  47 KQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFDAVRE-SALWPWLSNASFCACLAFAINTSAYTAEILAGSLKATPH 125
Cdd:PRK11122  40 KTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPWLQEyPWLWHLLSQPWLCAMLALALNSAAYSTQLFYGAVRAIPE 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414 126 GEIEAAKAMGMSRLKMYRrILLPSALRRALPQYSNEVIMMLQTTSLASIVTLVDITGAARTVYSQYYlPFEAFITAGLFY 205
Cdd:PRK11122 120 GQWQSCAALGMSKKQTLR-ILLPYAFKRALSSYSNEVVLVFKSTSLAYTITLMDVMGYSQLLYGRTY-DVMVFGAAGIIY 197

                        170       180
                 ....*....|....*....|.
gi 489176414 206 LCLTFILVRLFKLAERRWLAY 226
Cdd:PRK11122 198 LVVNGLLTLLMRLIERKALAF 218
ArtQ COG4215
ABC-type arginine transport system, permease component [Amino acid transport and metabolism];
41-222 3.15e-39

ABC-type arginine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443361 [Multi-domain]  Cd Length: 238  Bit Score: 135.25  E-value: 3.15e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  41 ALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQ-FDAVRESALWPWLSNAS--FCACLAFAINTSAYTAEILA 117
Cdd:COG4215   44 ALAKLSGNRPLRWLATGYTTVVRGVPDLLLILLLYFGGQIlLNALADLFGYDGFIEINpfVAGVLALGFVFGAYATEVFR 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414 118 GSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEVIMMLQTTSLASIVTLVDITGAARTVYSQYYLPFEA 197
Cdd:COG4215  124 GAFLAVPKGQIEAARAYGMSRWQVFRRILLPQMWRYALPGLGNNWLVLLKDTALVSVIGLVDLVRQAQEAAGSTREPFTF 203

                        170       180
                 ....*....|....*....|....*
gi 489176414 198 FITAGLFYLCLTFILVRLFKLAERR 222
Cdd:COG4215  204 YLAAALIYLALTTVSELVLARLERR 228
PRK15100 PRK15100
cystine ABC transporter permease;
5-222 5.49e-32

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 116.00  E-value: 5.49e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   5 FSVIWDSLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFDAv 84
Cdd:PRK15100   5 IQLVIDSAPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLPQFGI- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  85 resALWPWLSnasfcACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEVIM 164
Cdd:PRK15100  84 ---ELDPIPA-----AMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFIS 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489176414 165 MLQTTSLASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERR 222
Cdd:PRK15100 156 LVKDTSLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSALQNRFENQ 213
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 1-222 4.93e-31

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 113.61  E-value: 4.93e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   1 MIFDFSVIWDSLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQ 80
Cdd:PRK09494   1 MQFDWSAIWPAIPLLLEGAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVFIELIRGTPIVVQVMFIYFALPM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  81 -FDAVRESALWpwlsnasfCACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYS 159
Cdd:PRK09494  81 aFNDLRIDPFT--------AAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLG 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489176414 160 NEVIMMLQTTSLASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERR 222
Cdd:PRK09494 153 NQWIISIKDTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVIYLIITLVLSFILRRLERR 215
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 3-222 8.55e-30

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 110.33  E-value: 8.55e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414    3 FDFSVIWDSLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFd 82
Cdd:TIGR03003   1 WDWEFVRQILPTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDI- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   83 AVRESALwpwlsnasFCACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEV 162
Cdd:TIGR03003  80 GIRLPAL--------VAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYL 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  163 IMMLQTTSLASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERR 222
Cdd:TIGR03003 152 VAMFKETPVLSAITVLELMNQAKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEAR 211
ectoine_ehuC TIGR03004
ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are ...
 10-222 1.64e-23

ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons. Permease subunits EhuC and EhuD are homologous.


Pssm-ID: 132049 [Multi-domain]  Cd Length: 214  Bit Score: 93.76  E-value: 1.64e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   10 DSLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFDAvresAL 89
Cdd:TIGR03004   2 AYLPLLLQGAWVTMQITLAGSVLATVLAFFAGLGRVSGGPILRTVALCYIEVFRGTSLLVQLFWFYFVLPLIGL----SL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   90 WPWLSnasfcACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEVIMMLQTT 169
Cdd:TIGR03004  78 DPVTT-----GVMVLGLHAGAYGAEIVRGALSSVSVQQLEACRALNFTRFQTLRRISLPQALVEMMPAFGNLAIELLKLT 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 489176414  170 SLASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERR 222
Cdd:TIGR03004 153 SLVSLISLADLTFAAQSIRNLTLDTLSIFAITLLCYFVMALIIMLIMRVLERV 205
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
37-222 1.15e-20

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 87.04  E-value: 1.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  37 AVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQ--------FDAVRESALWPWLSNASF-------CAC 101
Cdd:PRK11123  29 AMLFAVWESAKWRPVAWPGTALVTLLRGLPEILVVLFIYFGSSQllltlsdgFTLNLGFVQIPVQMDIENfevspflCGV 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414 102 LAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEVIMMLQTTSLASIVTLVDIT 181
Cdd:PRK11123 109 IALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLGNQWLVLLKDTALVSLISVNDLM 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 489176414 182 GAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERR 222
Cdd:PRK11123 189 LQTKSIATRTQEPFTWYIIAAAIYLVITLISQYILKRIELR 229
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
14-223 8.22e-18

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 79.07  E-value: 8.22e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  14 LYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLA-QFDAVRESALWPW 92
Cdd:PRK15135   8 VILQGALVTLELALSSVVLAVIIGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPDLVLMLLIFYGLQiALNSVTEALGVGQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  93 LSNASFCA-CLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEVIMMLQTTSL 171
Cdd:PRK15135  88 IDIDPMVAgIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQVILKATAL 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489176414 172 ASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTFILVRLFKLAERRW 223
Cdd:PRK15135 168 VSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLWLERRY 219
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 11-118 6.64e-17

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 73.34  E-value: 6.64e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   11 SLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFdAVRESALW 90
Cdd:TIGR01726   1 NLPFLLKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLI-GIRLSPLT 79

                          90       100
                  ....*....|....*....|....*...
gi 489176414   91 pwlsnasfCACLAFAINTSAYTAEILAG 118
Cdd:TIGR01726  80 --------AAVIALTLFYGAYLAEIFRG 99
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 37-213 2.12e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 68.84  E-value: 2.12e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  37 AVPLALMRVSKQPLVNFPAWLYTYVIRGTPMLVQLFLIYYGLAQFdavresALWPWLSNASFCACLAFAINTSAYTAEIL 116
Cdd:cd06261   19 GLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVL------LGWGILPGLGLPALILALLLIAPFARLIR 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414 117 AGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEVIMMLQTTSLASIVTLVDITGAARTVYSQYYLPFE 196
Cdd:cd06261   93 RAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGLLLIFAILFP 172

                        170
                 ....*....|....*..
gi 489176414 197 AFITAGLFYLCLTFILV 213
Cdd:cd06261  173 GDLGVAAAVALILLLLS 189
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
3-210 2.93e-14

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 69.09  E-value: 2.93e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   3 FDFSVIWDSLPLYFDGLLVTLKLLSISLLIGLLLAVPLALMRVSKQPLVNFPAWLYTYVIRGTPmLVQLFLIYYGLAQFD 82
Cdd:PRK15107   4 FDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIP-LVMVLLWFYLIVPGF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  83 AVRESALWPWLSNASFCACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALPQYSNEV 162
Cdd:PRK15107  83 LQNVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQG 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 489176414 163 IMMLQTTSLASIVTLVDITGAARTVYSQYYLPFEAFITAGLFYLCLTF 210
Cdd:PRK15107 163 IVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISL 210
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 58-222 1.12e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 53.07  E-value: 1.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414   58 YTYVIRGTPMLVQLFLIYYGLaqFDAVRESALWPWLsnasfcacLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMS 137
Cdd:pfam00528  23 LIDLLQALPSFVLAILLVVIA--ILSILGHGILPAI--------ILALLGWAGYARLIRRAALRSLPSDLVEAARALGAS 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414  138 RLKMYRRILLPSALRRALPQYSNEVIMMLQTTSLASIVTLVDITGAARTV---YSQYYLPFEAFITAGLFYLCLTFILVR 214
Cdd:pfam00528  93 RWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEailGYDYPEIQGPVLAAALILLLLNLLVDI 172


                  ....*...
gi 489176414  215 LFKLAERR 222
Cdd:pfam00528 173 LQRLLDPR 180
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 97-160 5.45e-08

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 52.46  E-value: 5.45e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489176414  97 SFCAC-LAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSALRRALP----QYSN 160
Cdd:COG4597  264 EFVALlLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIPpltsQYLN 332
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 100-151 1.33e-04

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 41.58  E-value: 1.33e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489176414 100 ACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSAL 151
Cdd:COG2011   95 AIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEAL 146
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
100-151 2.23e-03

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 38.18  E-value: 2.23e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489176414 100 ACLAFAINTSAYTAEILAGSLKATPHGEIEAAKAMGMSRLKMYRRILLPSAL 151
Cdd:PRK10782  92 AIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEAL 143
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 120-222 7.55e-03

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 36.19  E-value: 7.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489176414 120 LKATPHGEIEAAKAMGMSRLKMYRRILLPSALRralpqysneVIM------MLQTTSLASIVTLVDITGAARTVYSQYYL 193
Cdd:COG1174  105 LRSVDPAVVEAARGMGMTPWQRLWRVELPLALP---------VILagirtaAVQNIGTATLAALIGAGGLGDLIFDGLQL 175

                         90       100       110
                 ....*....|....*....|....*....|
gi 489176414 194 PFEAFITAG-LFYLCLTFILVRLFKLAERR 222
Cdd:COG1174  176 NNTALILAGaILVALLALLVDLLLALLERL 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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