MULTISPECIES: M48 family metallopeptidase [Pseudomonas]
Protein Classification
M48 family metallopeptidase( domain architecture ID 11574951)
M48 family metallopeptidase, a member of a zinc metalloprotease family, which typically contains an HExxH motif characteristic of zinc metallopeptidases, and proteolytically removes the C-terminal three residues of farnesylated proteins
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| M48_yhfN_like | cd07344 | Peptidase M48 YhfN-like, a novel minigluzincin; M48 YhfN-like protease is considered as a CaaX ... |
110-150 | 5.99e-10 | ||
Peptidase M48 YhfN-like, a novel minigluzincin; M48 YhfN-like protease is considered as a CaaX prenyl protease 1 homolog, with most of the sequences in this family as yet uncharacterized. It contains the zinc metalloprotease motif (HEXXH), likely exposed on the cytoplasmic side. It is probably associated with the endoplasmic reticulum (ER), regardless of whether its genes possess the conventional signal motif (KKXX) in the C-terminal. Proteins in this family proteolytically remove the C-terminal three residues of farnesylated proteins. This novel family of related proteins consist of the soluble minimal scaffold similar to the catalytic domains of the integral-membrane metallopeptidase M48 and M56, thus called minigluzincins. : Pssm-ID: 320703 Cd Length: 96 Bit Score: 53.22 E-value: 5.99e-10
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| Name | Accession | Description | Interval | E-value | ||
| M48_yhfN_like | cd07344 | Peptidase M48 YhfN-like, a novel minigluzincin; M48 YhfN-like protease is considered as a CaaX ... |
110-150 | 5.99e-10 | ||
Peptidase M48 YhfN-like, a novel minigluzincin; M48 YhfN-like protease is considered as a CaaX prenyl protease 1 homolog, with most of the sequences in this family as yet uncharacterized. It contains the zinc metalloprotease motif (HEXXH), likely exposed on the cytoplasmic side. It is probably associated with the endoplasmic reticulum (ER), regardless of whether its genes possess the conventional signal motif (KKXX) in the C-terminal. Proteins in this family proteolytically remove the C-terminal three residues of farnesylated proteins. This novel family of related proteins consist of the soluble minimal scaffold similar to the catalytic domains of the integral-membrane metallopeptidase M48 and M56, thus called minigluzincins. Pssm-ID: 320703 Cd Length: 96 Bit Score: 53.22 E-value: 5.99e-10
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| YgjP | COG1451 | UTP pyrophosphatase, metal-dependent hydrolase family [General function prediction only]; |
110-156 | 4.66e-09 | ||
UTP pyrophosphatase, metal-dependent hydrolase family [General function prediction only]; Pssm-ID: 441060 Cd Length: 236 Bit Score: 53.35 E-value: 4.66e-09
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| YgjP-like | pfam01863 | YgjP-like, metallopeptidase domain; This is a conserved domain containing the catalytic ... |
110-146 | 1.17e-08 | ||
YgjP-like, metallopeptidase domain; This is a conserved domain containing the catalytic zinc-metallopeptidase (HExxH) catalytic motif. Proteins containing this domain are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C terminus being the most conserved region, containing three conserved histidines. This domain is found in YgjP from E. coli, a predicted metal-dependent hydrolase that hydrolyses UTP to UMP and diphosphate in vitro; and in MJ0123 from Methanocaldococcus jannaschii (also referred to as projannalysin). Pssm-ID: 396437 Cd Length: 207 Bit Score: 51.91 E-value: 1.17e-08
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| Name | Accession | Description | Interval | E-value | ||
| M48_yhfN_like | cd07344 | Peptidase M48 YhfN-like, a novel minigluzincin; M48 YhfN-like protease is considered as a CaaX ... |
110-150 | 5.99e-10 | ||
Peptidase M48 YhfN-like, a novel minigluzincin; M48 YhfN-like protease is considered as a CaaX prenyl protease 1 homolog, with most of the sequences in this family as yet uncharacterized. It contains the zinc metalloprotease motif (HEXXH), likely exposed on the cytoplasmic side. It is probably associated with the endoplasmic reticulum (ER), regardless of whether its genes possess the conventional signal motif (KKXX) in the C-terminal. Proteins in this family proteolytically remove the C-terminal three residues of farnesylated proteins. This novel family of related proteins consist of the soluble minimal scaffold similar to the catalytic domains of the integral-membrane metallopeptidase M48 and M56, thus called minigluzincins. Pssm-ID: 320703 Cd Length: 96 Bit Score: 53.22 E-value: 5.99e-10
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| YgjP | COG1451 | UTP pyrophosphatase, metal-dependent hydrolase family [General function prediction only]; |
110-156 | 4.66e-09 | ||
UTP pyrophosphatase, metal-dependent hydrolase family [General function prediction only]; Pssm-ID: 441060 Cd Length: 236 Bit Score: 53.35 E-value: 4.66e-09
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| YgjP-like | pfam01863 | YgjP-like, metallopeptidase domain; This is a conserved domain containing the catalytic ... |
110-146 | 1.17e-08 | ||
YgjP-like, metallopeptidase domain; This is a conserved domain containing the catalytic zinc-metallopeptidase (HExxH) catalytic motif. Proteins containing this domain are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C terminus being the most conserved region, containing three conserved histidines. This domain is found in YgjP from E. coli, a predicted metal-dependent hydrolase that hydrolyses UTP to UMP and diphosphate in vitro; and in MJ0123 from Methanocaldococcus jannaschii (also referred to as projannalysin). Pssm-ID: 396437 Cd Length: 207 Bit Score: 51.91 E-value: 1.17e-08
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