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Conserved domains on  [gi|489126294|ref|WP_003036091|]
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MULTISPECIES: biofilm master transcriptional regulator CsgD [Citrobacter]

Protein Classification

LuxR family transcriptional regulator( domain architecture ID 11484577)

LuxR family transcriptional regulator similar to HTH-type transcriptional regulator EcpR, which regulates the expression of the ecp operon that is involved in early-stage biofilm development and host cell recognition

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10100 PRK10100
transcriptional regulator CsgD;
1-216 1.42e-152

transcriptional regulator CsgD;


:

Pssm-ID: 182241 [Multi-domain]  Cd Length: 216  Bit Score: 421.97  E-value: 1.42e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294   1 MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLALTGKLHNIQRSLDDISSSCIVLLDMMEADKKLIHYWQDNLSRKNN 80
Cdd:PRK10100   1 MFNEVHSSHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294  81 NIKTLLLNTPDDYPYRDIENWPHINGVFYATEDEQRVVSGLQGVLRGECYFSQKLASYLITHSGNYRYNSTESALLTHRE 160
Cdd:PRK10100  81 NIKILLLNTPEDYPYREIENWPHINGVFYAMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 489126294 161 KEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR 216
Cdd:PRK10100 161 KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR 216
 
Name Accession Description Interval E-value
PRK10100 PRK10100
transcriptional regulator CsgD;
1-216 1.42e-152

transcriptional regulator CsgD;


Pssm-ID: 182241 [Multi-domain]  Cd Length: 216  Bit Score: 421.97  E-value: 1.42e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294   1 MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLALTGKLHNIQRSLDDISSSCIVLLDMMEADKKLIHYWQDNLSRKNN 80
Cdd:PRK10100   1 MFNEVHSSHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294  81 NIKTLLLNTPDDYPYRDIENWPHINGVFYATEDEQRVVSGLQGVLRGECYFSQKLASYLITHSGNYRYNSTESALLTHRE 160
Cdd:PRK10100  81 NIKILLLNTPEDYPYREIENWPHINGVFYAMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 489126294 161 KEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR 216
Cdd:PRK10100 161 KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR 216
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 153-213 7.73e-22

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 86.87  E-value: 7.73e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489126294 153 SALLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDN 213
Cdd:COG2197   67 RRLLTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELVLLALRL 127
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 154-210 7.74e-21

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 81.80  E-value: 7.74e-21
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 489126294   154 ALLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
Cdd:smart00421   2 ASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 156-212 5.98e-19

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 76.80  E-value: 5.98e-19
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489126294 156 LTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWAND 212
Cdd:cd06170    1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYAIR 57
GerE pfam00196
Bacterial regulatory proteins, luxR family;
156-210 8.52e-18

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 73.77  E-value: 8.52e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 489126294  156 LTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
Cdd:pfam00196   3 LSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
 
Name Accession Description Interval E-value
PRK10100 PRK10100
transcriptional regulator CsgD;
1-216 1.42e-152

transcriptional regulator CsgD;


Pssm-ID: 182241 [Multi-domain]  Cd Length: 216  Bit Score: 421.97  E-value: 1.42e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294   1 MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLALTGKLHNIQRSLDDISSSCIVLLDMMEADKKLIHYWQDNLSRKNN 80
Cdd:PRK10100   1 MFNEVHSSHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294  81 NIKTLLLNTPDDYPYRDIENWPHINGVFYATEDEQRVVSGLQGVLRGECYFSQKLASYLITHSGNYRYNSTESALLTHRE 160
Cdd:PRK10100  81 NIKILLLNTPEDYPYREIENWPHINGVFYAMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 489126294 161 KEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR 216
Cdd:PRK10100 161 KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR 216
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 153-213 7.73e-22

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 86.87  E-value: 7.73e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489126294 153 SALLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDN 213
Cdd:COG2197   67 RRLLTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELVLLALRL 127
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 150-210 4.82e-21

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 83.09  E-value: 4.82e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489126294 150 STESALLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
Cdd:COG5905    7 TSHPSLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAVVWA 67
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 154-210 7.74e-21

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 81.80  E-value: 7.74e-21
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 489126294   154 ALLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
Cdd:smart00421   2 ASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 156-212 5.98e-19

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 76.80  E-value: 5.98e-19
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489126294 156 LTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWAND 212
Cdd:cd06170    1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYAIR 57
GerE pfam00196
Bacterial regulatory proteins, luxR family;
156-210 8.52e-18

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 73.77  E-value: 8.52e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 489126294  156 LTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
Cdd:pfam00196   3 LSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
156-210 1.67e-15

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 71.71  E-value: 1.67e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489126294 156 LTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
Cdd:COG2771  128 LTPREREVLRLLAEGLTLKEIARILGISERTVRTHLKRIYRKLGVSSRAELVALA 182
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
170-210 1.04e-13

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 66.65  E-value: 1.04e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 489126294 170 GASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
Cdd:COG2909  137 GLSNKEIAERLFISVNTVKTHLRNIYRKLGVRSRTEAVARA 177
PRK10651 PRK10651
transcriptional regulator NarL; Provisional
 115-215 1.64e-13

transcriptional regulator NarL; Provisional


Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 66.59  E-value: 1.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294 115 QRVVSGLQGVLRGECYFSQKLASYLITH-SGNYRYNSTESALLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYN 193
Cdd:PRK10651 114 EDLLKALQQAAAGEMVLSEALTPVLAASlRANRATTERDVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKH 193

                         90       100
                 ....*....|....*....|..
gi 489126294 194 LFKKIAVKNRTQAVSWANDNLR 215
Cdd:PRK10651 194 MLKKMKLKSRVEAAVWVHQERI 215
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
131-206 2.46e-10

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 57.94  E-value: 2.46e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489126294 131 FSQKLASYLITHSgnyRYNSTES--ALLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQA 206
Cdd:PRK10403 130 FSERVNQYLRERE---MFGAEEDpfSVLTERELDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAA 204
PRK15369 PRK15369
two component system response regulator;
114-210 1.02e-08

two component system response regulator;


Pssm-ID: 185267 [Multi-domain]  Cd Length: 211  Bit Score: 53.16  E-value: 1.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294 114 EQRVVSGLQGVLRGECYFSQKLASYLITHSGNYryNSTESALLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYN 193
Cdd:PRK15369 110 QQILLAAIQTVAVGKRYIDPALNREAILALLNA--DDTNPPLLTPRERQILKLITEGYTNRDIAEQLSISIKTVETHRLN 187

                         90
                 ....*....|....*..
gi 489126294 194 LFKKIAVKNRTQAVSWA 210
Cdd:PRK15369 188 MMRKLDVHKVAELLNWA 204
FixJ COG4566
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ...
 154-210 1.15e-08

DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 443623 [Multi-domain]  Cd Length: 196  Bit Score: 52.80  E-value: 1.15e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489126294 154 ALLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
Cdd:COG4566  136 ASLTPREREVLDLVVAGLSNKQIARELGISPRTVEVHRANVMEKLGARSLAELVRLA 192
PRK04841 PRK04841
HTH-type transcriptional regulator MalT;
156-215 1.15e-07

HTH-type transcriptional regulator MalT;


Pssm-ID: 235315 [Multi-domain]  Cd Length: 903  Bit Score: 51.48  E-value: 1.15e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294 156 LTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLR 215
Cdd:PRK04841 839 LTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQKLGIAHRQEAVQHAQDLLK 898
PRK09935 PRK09935
fimbriae biosynthesis transcriptional regulator FimZ;
79-210 1.36e-06

fimbriae biosynthesis transcriptional regulator FimZ;


Pssm-ID: 182154 [Multi-domain]  Cd Length: 210  Bit Score: 47.18  E-value: 1.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294  79 NNNIKTLLLNTPDDYPYRDIENWPHINGVFYATEDEQRVVSGLQGVLRGECYFSQKLASYlITHSGNYRyNSTESALLTH 158
Cdd:PRK09935  75 QSTVKVLFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMILSGYTFFPSETLNY-IKSNKCST-NSSTDTVLSN 152

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489126294 159 REKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
Cdd:PRK09935 153 REVTILRYLVSGLSNKEIADQLLLSNKTVSAHKSNIYGKLGLHSIVELIDYA 204
PRK10188 PRK10188
transcriptional regulator SdiA;
156-210 1.68e-06

transcriptional regulator SdiA;


Pssm-ID: 182292 [Multi-domain]  Cd Length: 240  Bit Score: 47.09  E-value: 1.68e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489126294 156 LTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWA 210
Cdd:PRK10188 180 FSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQKNMQKKFNAPNKTQIACYA 234
PRK10360 PRK10360
transcriptional regulator UhpA;
117-202 6.91e-05

transcriptional regulator UhpA;


Pssm-ID: 182408 [Multi-domain]  Cd Length: 196  Bit Score: 42.27  E-value: 6.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489126294 117 VVSGLQGVLRGECYFSQKLASYLITHSGNyrynstesaLLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFK 196
Cdd:PRK10360 108 LIAAVHTVATGGCYLTPDIAIKLASGRQD---------PLTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLME 178


                 ....*.
gi 489126294 197 KIAVKN 202
Cdd:PRK10360 179 KLGVSN 184
fixJ PRK09390
response regulator FixJ; Provisional
 154-202 6.60e-03

response regulator FixJ; Provisional


Pssm-ID: 181815 [Multi-domain]  Cd Length: 202  Bit Score: 36.52  E-value: 6.60e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 489126294 154 ALLTHREKEILNKLRIGASNIEIARSLFISENTVKTHLYNLFKKIAVKN 202
Cdd:PRK09390 140 ASLSERERQVMDGLVAGLSNKVIARDLDISPRTVEVYRANVMTKMQAGS 188
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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