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Conserved domains on  [gi|489124052|ref|WP_003033852|]
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MULTISPECIES: GNAT family N-acetyltransferase [Citrobacter]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11441181)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-163 7.57e-59

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


:

Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 180.96  E-value: 7.57e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   1 MKIVNAEEKHIPAIRDIYAHHVLHGTGSFETDPPDAHQMFARLEKIRSLGLPWVVALQEDKVIGYCYLTRYRERYAYRYT 80
Cdd:COG1247    2 MTIRPATPEDAPAIAAIYNEAIAEGTATFETEPPSEEEREAWFAAILAPGRPVLVAEEDGEVVGFASLGPFRPRPAYRGT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052  81 LEDSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVGDSnNQGSLKVHQQAGFTEIGTLKNIGFKHGLWLDTVLLQ 160
Cdd:COG1247   82 AEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLAD-NEASIALYEKLGFEEVGTLPEVGFKFGRWLDLVLMQ 160


                 ...
gi 489124052 161 RNL 163
Cdd:COG1247  161 KRL 163
 
Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-163 7.57e-59

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 180.96  E-value: 7.57e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   1 MKIVNAEEKHIPAIRDIYAHHVLHGTGSFETDPPDAHQMFARLEKIRSLGLPWVVALQEDKVIGYCYLTRYRERYAYRYT 80
Cdd:COG1247    2 MTIRPATPEDAPAIAAIYNEAIAEGTATFETEPPSEEEREAWFAAILAPGRPVLVAEEDGEVVGFASLGPFRPRPAYRGT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052  81 LEDSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVGDSnNQGSLKVHQQAGFTEIGTLKNIGFKHGLWLDTVLLQ 160
Cdd:COG1247   82 AEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLAD-NEASIALYEKLGFEEVGTLPEVGFKFGRWLDLVLMQ 160


                 ...
gi 489124052 161 RNL 163
Cdd:COG1247  161 KRL 163
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 14-137 3.48e-14

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 65.23  E-value: 3.48e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   14 IRDIYAHHVLHGTGSFETDPPDAHQMFARLEKIRSLglpwvVALQEDKVIGYCYLTRYRERYAYRYtlEDSIYIAPTAQR 93
Cdd:pfam00583   1 LEALYELLSEEFPEPWPDEPLDLLEDWDEDASEGFF-----VAEEDGELVGFASLSIIDDEPPVGE--IEGLAVAPEYRG 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 489124052   94 QGVGKALLRHVIGWAEAQGYRQLIAIVgDSNNQGSLKVHQQAGF 137
Cdd:pfam00583  74 KGIGTALLQALLEWARERGCERIFLEV-AADNLAAIALYEKLGF 116
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 53-117 3.67e-10

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 53.43  E-value: 3.67e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489124052  53 WVVALQEDKVIGYCYLTRYRERYAyryTLE-DSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLI 117
Cdd:cd04301    1 FLVAEDDGEIVGFASLSPDGSGGD---TAYiGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLR 63
rimI PRK09491
ribosomal-protein-alanine N-acetyltransferase; Provisional
 85-145 1.62e-05

ribosomal-protein-alanine N-acetyltransferase; Provisional


Pssm-ID: 181904 [Multi-domain]  Cd Length: 146  Bit Score: 42.61  E-value: 1.62e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489124052  85 IYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVGDSnNQGSLKVHQQAGFTEIGTLKN 145
Cdd:PRK09491  69 IAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRAS-NAAAIALYESLGFNEVTIRRN 128
 
Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-163 7.57e-59

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 180.96  E-value: 7.57e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   1 MKIVNAEEKHIPAIRDIYAHHVLHGTGSFETDPPDAHQMFARLEKIRSLGLPWVVALQEDKVIGYCYLTRYRERYAYRYT 80
Cdd:COG1247    2 MTIRPATPEDAPAIAAIYNEAIAEGTATFETEPPSEEEREAWFAAILAPGRPVLVAEEDGEVVGFASLGPFRPRPAYRGT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052  81 LEDSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVGDSnNQGSLKVHQQAGFTEIGTLKNIGFKHGLWLDTVLLQ 160
Cdd:COG1247   82 AEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLAD-NEASIALYEKLGFEEVGTLPEVGFKFGRWLDLVLMQ 160


                 ...
gi 489124052 161 RNL 163
Cdd:COG1247  161 KRL 163
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 6-161 7.34e-22

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 86.98  E-value: 7.34e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   6 AEEKHIPAIRDIYAH-HVLHGTGSFETDPPDAHQMFARLEKIRSLG--LPWVVALQED-KVIGYCYLTRYRERYAyryTL 81
Cdd:COG1670   13 LRPEDAEALAELLNDpEVARYLPGPPYSLEEARAWLERLLADWADGgaLPFAIEDKEDgELIGVVGLYDIDRANR---SA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052  82 EDSIYIAPTAQRQGVGKALLRHVIGWA-EAQGYRQLIAIVgDSNNQGSLKVHQQAGFTEIGTLKNIGFKHGLWLDTVLLQ 160
Cdd:COG1670   90 EIGYWLAPAYWGKGYATEALRALLDYAfEELGLHRVEAEV-DPDNTASIRVLEKLGFRLEGTLRDALVIDGRYRDHVLYS 168


                 .
gi 489124052 161 R 161
Cdd:COG1670  169 L 169
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
3-143 7.47e-16

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 70.50  E-value: 7.47e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   3 IVNAEEKHIPAIRDIYAHhvlhgtgSFetDPPDAHQMFARLEKIRSLGLPWVvALQEDKVIGYCYLTRYRERYAYRYTLE 82
Cdd:COG3153    1 IRPATPEDAEAIAALLRA-------AF--GPGREAELVDRLREDPAAGLSLV-AEDDGEIVGHVALSPVDIDGEGPALLL 70

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489124052  83 DSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRqLIAIVGDSNNQGslkVHQQAGFTEIGTL 143
Cdd:COG3153   71 GPLAVDPEYRGQGIGRALMRAALEAARERGAR-AVVLLGDPSLLP---FYERFGFRPAGEL 127
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 14-137 3.48e-14

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 65.23  E-value: 3.48e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   14 IRDIYAHHVLHGTGSFETDPPDAHQMFARLEKIRSLglpwvVALQEDKVIGYCYLTRYRERYAYRYtlEDSIYIAPTAQR 93
Cdd:pfam00583   1 LEALYELLSEEFPEPWPDEPLDLLEDWDEDASEGFF-----VAEEDGELVGFASLSIIDDEPPVGE--IEGLAVAPEYRG 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 489124052   94 QGVGKALLRHVIGWAEAQGYRQLIAIVgDSNNQGSLKVHQQAGF 137
Cdd:pfam00583  74 KGIGTALLQALLEWARERGCERIFLEV-AADNLAAIALYEKLGF 116
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 83-154 7.04e-13

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 61.21  E-value: 7.04e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489124052  83 DSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVgDSNNQGSLKVHQQAGFTEIGTLKNIGFKHGLWL 154
Cdd:COG0456   17 EDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEV-REDNEAAIALYEKLGFEEVGERPNYYGDDALVM 87
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 1-141 3.33e-12

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 60.39  E-value: 3.33e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   1 MKIVNAEEKHIPAIRDIYAHHVLHgtgsfetdppDAHQMFarlekirslglpwVVALQEDKVIGYCYLTRYRERyayryT 80
Cdd:COG1246    1 MTIRPATPDDVPAILELIRPYALE----------EEIGEF-------------WVAEEDGEIVGCAALHPLDED-----L 52

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489124052  81 LE-DSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVgdsnNQGSLKVHQQAGFTEIG 141
Cdd:COG1246   53 AElRSLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLT----TSAAIHFYEKLGFEEID 110
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 1-145 6.38e-12

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 59.68  E-value: 6.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   1 MKIVNAEEKHIPAIRDIyahhvlhgtgsfetdppdaHQMFARLEKIRSL--GLPWVVALQEDKVIGYCYLTRYRERyayr 78
Cdd:COG0454    1 MSIRKATPEDINFILLI-------------------EALDAELKAMEGSlaGAEFIAVDDKGEPIGFAGLRRLDDK---- 57

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489124052  79 yTLE-DSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVGDsNNQGSLKVHQQAGFTEIGTLKN 145
Cdd:COG0454   58 -VLElKRLYVLPEYRGKGIGKALLEALLEWARERGCTALELDTLD-GNPAAIRFYERLGFKEIERYVA 123
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 7-138 2.52e-10

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 55.81  E-value: 2.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052    7 EEKHIPAIRDIYAH-HVLHGTGSFETDPPDAHQMFAR--LEKIRSLGLPWVVALQEDKVIGYCYLTRYRERYAyryTLED 83
Cdd:pfam13302   8 TEEDAEALFELLSDpEVMRYGVPWPLTLEEAREWLARiwAADEAERGYGWAIELKDTGFIGSIGLYDIDGEPE---RAEL 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 489124052   84 SIYIAPTAQRQGVG----KALLRHvigWAEAQGYRQLIAIVgDSNNQGSLKVHQQAGFT 138
Cdd:pfam13302  85 GYWLGPDYWGKGYAteavRALLEY---AFEELGLPRLVARI-DPENTASRRVLEKLGFK 139
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 53-117 3.67e-10

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 53.43  E-value: 3.67e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489124052  53 WVVALQEDKVIGYCYLTRYRERYAyryTLE-DSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLI 117
Cdd:cd04301    1 FLVAEDDGEIVGFASLSPDGSGGD---TAYiGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLR 63
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 54-139 4.90e-09

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 50.92  E-value: 4.90e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   54 VVALQEDKVIGYCYLTRYRERYAYrytLEDSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAivgdSNNQGSLKVHQ 133
Cdd:pfam13508   6 FVAEDDGKIVGFAALLPLDDEGAL---AELRLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLEL----ETTNRAAAFYE 78


                  ....*.
gi 489124052  134 QAGFTE 139
Cdd:pfam13508  79 KLGFEE 84
COG3818 COG3818
Predicted N-acetyltransferase, GNAT superfamily [General function prediction only];
83-143 9.52e-09

Predicted N-acetyltransferase, GNAT superfamily [General function prediction only];


Pssm-ID: 443030 [Multi-domain]  Cd Length: 168  Bit Score: 51.86  E-value: 9.52e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489124052  83 DSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVG-DSNNQGSLKVHQQAGFTEIGTL 143
Cdd:COG3818   88 DRIVVAPSARGRGLGRALYADVFSYARARGVPRVTCEVNlEPPNPGSLAFHARLGFREVGQQ 149
rimI PRK09491
ribosomal-protein-alanine N-acetyltransferase; Provisional
 85-145 1.62e-05

ribosomal-protein-alanine N-acetyltransferase; Provisional


Pssm-ID: 181904 [Multi-domain]  Cd Length: 146  Bit Score: 42.61  E-value: 1.62e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489124052  85 IYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVGDSnNQGSLKVHQQAGFTEIGTLKN 145
Cdd:PRK09491  69 IAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRAS-NAAAIALYESLGFNEVTIRRN 128
PRK10140 PRK10140
N-acetyltransferase;
3-161 3.11e-05

N-acetyltransferase;


Pssm-ID: 182263 [Multi-domain]  Cd Length: 162  Bit Score: 42.28  E-value: 3.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   3 IVNAEEKHIPAIRDIYAH-HVLHGTgsFETDPPDAHQMFARLEKirSLGLPWVVALQEDKVIGycYLTRYRERYAYRYTL 81
Cdd:PRK10140   6 IRHAETRDYEAIRQIHAQpEVYHNT--LQVPHPSDHMWQERLAD--RPGIKQLVACIDGDVVG--HLTIDVQQRPRRSHV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052  82 ED-SIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVGDSNNQGSLKVHQQAGFTEIGTLKNIGFKHGLWLDTVLLQ 160
Cdd:PRK10140  80 ADfGICVDSRWKNRGVASALMREMIEMCDNWLRVDRIELTVFVDNAPAIKVYKKYGFEIEGTGKKYALRNGEYVDAYYMA 159


                 .
gi 489124052 161 R 161
Cdd:PRK10140 160 R 160
PRK07757 PRK07757
N-acetyltransferase;
1-118 3.77e-05

N-acetyltransferase;


Pssm-ID: 236088 [Multi-domain]  Cd Length: 152  Bit Score: 41.72  E-value: 3.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   1 MKIVNAEEKHIPAIRDIYAHHVLHGtgsfetdppdahQMFAR-----LEKIRSLglpwVVALQEDKVIGYCYLTRYRery 75
Cdd:PRK07757   2 MEIRKARLSDVKAIHALINVYAKKG------------LMLPRsldelYENIRDF----YVAEEEGEIVGCCALHILW--- 62

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 489124052  76 ayrytlED-----SIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIA 118
Cdd:PRK07757  63 ------EDlaeirSLAVSEDYRGQGIGRMLVEACLEEARELGVKRVFA 104
Acetyltransf_4 pfam13420
Acetyltransferase (GNAT) domain;
3-158 5.52e-05

Acetyltransferase (GNAT) domain;


Pssm-ID: 433192 [Multi-domain]  Cd Length: 153  Bit Score: 41.20  E-value: 5.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052    3 IVNAEEKHIPAIRDIYAHHVLHGTGSFETDPPDAHQMFARLEKIRSLGLPWVVALQEDKVIGYCYLTRYRERYAYRYTLe 82
Cdd:pfam13420   1 IRALTQNDLKEIRRWYAEDRVNPAFTQEYAHSSIEEFETFLAAYLSPGEIVFGVAESDRLIGYATLRQFDYVKTHKAEL- 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489124052   83 dSIYIApTAQRQGVGKALLRHVIGWAEA-QGYRQLIAIVGdSNNQGSLKVHQQAGFTEIGTLKNIGFKHGLWLDTVL 158
Cdd:pfam13420  80 -SFYVV-KNNDEGINRELINAIIQYARKnQNIENLEACIA-SNNINAIVFLKAIGFEWLGIERNAIKKNGRWIDMMW 153
COG3981 COG3981
Predicted acetyltransferase [General function prediction only];
87-131 7.15e-04

Predicted acetyltransferase [General function prediction only];


Pssm-ID: 443180  Cd Length: 170  Bit Score: 38.35  E-value: 7.15e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 489124052  87 IAPTAQRQGVGKALLRHVIGWAEAQGYRQLIaIVGDSNNQGSLKV 131
Cdd:COG3981   99 VRPSERGKGYATEMLRLALEEARELGLDRVL-ITCDKDNIASRKV 142
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 44-141 1.70e-03

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 36.87  E-value: 1.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489124052   44 EKIRSLGLPWVVALQEDKVIGYCYLTRYRERyayrytleDSIYIAPTAQRQGVGKALLRHVIGWAEAQGYRQLIAIVGDS 123
Cdd:pfam13673  24 ERIDQGEYFFFVAFEGGQIVGVIALRDRGHI--------SLLFVDPDYQGQGIGKALLEAVEDYAEKDGIKLSELTVNAS 95

                          90
                  ....*....|....*...
gi 489124052  124 NNqgSLKVHQQAGFTEIG 141
Cdd:pfam13673  96 PY--AVPFYEKLGFRATG 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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