|
Name |
Accession |
Description |
Interval |
E-value |
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
1-323 |
0e+00 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 668.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 1 MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMI 80
Cdd:PRK02458 1 MTERYADKQIKLFSLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 81 DACKRASANTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER 160
Cdd:PRK02458 81 DACKRASANTVNVVLPYFGYARQDRIAKPREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 161 YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKI 240
Cdd:PRK02458 161 YCKKGLSGSDVVVVSPKNSGIKRARSLAEYLDAPIAIIDYAQDDSEREEGYIIGDVAGKKAILIDDILNTGKTFAEAAKI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 241 LERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQP 320
Cdd:PRK02458 241 VEREGATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSVATKERVPKNVTYLSASELIADAIIRIHERKPLSPLFAYNK 320
|
...
gi 489079890 321 KGK 323
Cdd:PRK02458 321 KGK 323
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
7-317 |
1.30e-165 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 463.38 E-value: 1.30e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 7 DKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRA 86
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 87 SANTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLGL 166
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 167 sgSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQD-DSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSG 245
Cdd:COG0462 161 --EDLVVVSPDVGGVKRARAFAKRLGAPLAIIDKRRPgANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAG 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489079890 246 ATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVK-TKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFS 317
Cdd:COG0462 239 AKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPlPEEKRCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
10-317 |
8.32e-126 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 362.37 E-value: 8.32e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 10 IKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYII-QSTSFPVNDNLWELLIMIDACKRASA 88
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 89 NTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLGLsg 168
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKIL-- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 169 SDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSER--EQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSGA 246
Cdd:TIGR01251 159 DNPVVVSPDAGGVERAKKVADALGCPLAIIDKRRISATNevEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489079890 247 TDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVKTKNRVPeNVTYLSASDLIAEAIIRIHERRPLSPLFS 317
Cdd:TIGR01251 239 KRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEKHKP-KVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
10-126 |
1.15e-70 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 214.98 E-value: 1.15e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 10 IKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASAN 89
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 489079890 90 TVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAG 126
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKPREPITAKLVADLLEAAG 117
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
154-279 |
3.68e-20 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 84.75 E-value: 3.68e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 154 VPLFAERYSKLGlsGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQG-------YIIGDVSGKKAILIDD 226
Cdd:cd06223 2 GRLLAEEIREDL--LEPDVVVGILRGGLPLAAALARALGLPLAFIRKERKGPGRTPSepyglelPLGGDVKGKRVLLVDD 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 489079890 227 ILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAAEvlETAPIKEIIVTDS 279
Cdd:cd06223 80 VIATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGARE--LASPGDPVYSLFT 130
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
1-323 |
0e+00 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 668.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 1 MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMI 80
Cdd:PRK02458 1 MTERYADKQIKLFSLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 81 DACKRASANTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER 160
Cdd:PRK02458 81 DACKRASANTVNVVLPYFGYARQDRIAKPREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 161 YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKI 240
Cdd:PRK02458 161 YCKKGLSGSDVVVVSPKNSGIKRARSLAEYLDAPIAIIDYAQDDSEREEGYIIGDVAGKKAILIDDILNTGKTFAEAAKI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 241 LERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQP 320
Cdd:PRK02458 241 VEREGATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSVATKERVPKNVTYLSASELIADAIIRIHERKPLSPLFAYNK 320
|
...
gi 489079890 321 KGK 323
Cdd:PRK02458 321 KGK 323
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
7-317 |
1.30e-165 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 463.38 E-value: 1.30e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 7 DKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRA 86
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 87 SANTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLGL 166
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 167 sgSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQD-DSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSG 245
Cdd:COG0462 161 --EDLVVVSPDVGGVKRARAFAKRLGAPLAIIDKRRPgANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAG 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489079890 246 ATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVK-TKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFS 317
Cdd:COG0462 239 AKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPlPEEKRCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
10-316 |
2.11e-150 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 424.53 E-value: 2.11e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 10 IKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASAN 89
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 90 TVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLGLsgS 169
Cdd:PRK01259 81 RITAVIPYFGYARQDRKARSRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQKNL--E 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 170 DVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQD-DSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSGATD 248
Cdd:PRK01259 159 NLVVVSPDVGGVVRARALAKRLDADLAIIDKRRPrANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKS 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 249 TYAVASHGLFAGGAAEVLETAPIKEIIVTDSVKTKNRV--PENVTYLSASDLIAEAIIRIHERRPLSPLF 316
Cdd:PRK01259 239 VYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAkkCDKIRVLSVAPLLAEAIRRISNEESVSSLF 308
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
10-319 |
1.77e-141 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 402.63 E-value: 1.77e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 10 IKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASAN 89
Cdd:PRK02269 6 LKLFALSSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 90 TVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLGLSGS 169
Cdd:PRK02269 86 SINVVMPYYGYARQDRKARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRGLVGD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 170 DVVVVSPKNSGIKRARSLAEYLDSPIAIIDY---AQDDSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSGA 246
Cdd:PRK02269 166 DVVVVSPDHGGVTRARKLAQFLKTPIAIIDKrrsVDKMNTSEVMNIIGNVKGKKCILIDDMIDTAGTICHAADALAEAGA 245
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489079890 247 TDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVKT-KNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQ 319
Cdd:PRK02269 246 TEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIYLpEERLIDKIEQISIADLLGEAIIRIHEKRPLSPLFEMG 319
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
10-317 |
8.32e-126 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 362.37 E-value: 8.32e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 10 IKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYII-QSTSFPVNDNLWELLIMIDACKRASA 88
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 89 NTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLGLsg 168
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKIL-- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 169 SDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSER--EQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSGA 246
Cdd:TIGR01251 159 DNPVVVSPDAGGVERAKKVADALGCPLAIIDKRRISATNevEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489079890 247 TDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVKTKNRVPeNVTYLSASDLIAEAIIRIHERRPLSPLFS 317
Cdd:TIGR01251 239 KRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEKHKP-KVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
7-316 |
1.14e-109 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 322.08 E-value: 1.14e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 7 DKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRA 86
Cdd:PRK02812 19 NNRLRLFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRRA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 87 SANTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLGL 166
Cdd:PRK02812 99 SARQITAVIPYYGYARADRKTAGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLASKNL 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 167 sgSDVVVVSPKNSGIKRARSLAEYL-DSPIAIIDyaqddsEREQGY-------IIGDVSGKKAILIDDILNTGKTFAEAA 238
Cdd:PRK02812 179 --EDIVVVSPDVGGVARARAFAKKLnDAPLAIID------KRRQAHnvaevlnVIGDVKGKTAILVDDMIDTGGTICEGA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 239 KILERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDS--VKTKNRVPEnVTYLSASDLIAEAIIRIHERRPLSPLF 316
Cdd:PRK02812 251 RLLRKEGAKQVYACATHAVFSPPAIERLSSGLFEEVIVTNTipVPEERRFPQ-LKVLSVANMLGEAIWRIHEESSVSSMF 329
|
|
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
20-316 |
3.17e-105 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 309.70 E-value: 3.17e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 20 PIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFG 99
Cdd:PLN02369 2 ALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYFG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 100 YSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLGLSGSDVVVVSPKNS 179
Cdd:PLN02369 82 YARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTISSPDLVVVSPDVG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 180 GIKRARSLAEYL-DSPIAIIDYA-QDDSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGL 257
Cdd:PLN02369 162 GVARARAFAKKLsDAPLAIVDKRrQGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYACATHAV 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 258 FAGGAAEVLETAPIKEIIVTDSVKTKN-RVPENVTYLSASDLIAEAIIRIHERRPLSPLF 316
Cdd:PLN02369 242 FSPPAIERLSSGLFQEVIVTNTIPVSEkNYFPQLTVLSVANLLGETIWRVHDDCSVSSIF 301
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
22-320 |
2.58e-93 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 279.53 E-value: 2.58e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 22 AEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYS 101
Cdd:PRK03092 2 AEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPYA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 102 RQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAErYSKLGLSGSDVVVVSPKNSGI 181
Cdd:PRK03092 82 RQDKKHRGREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLAD-YVRDKYDLDNVTVVSPDAGRV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 182 KRARSLAEYL-DSPIAIIDYAQDDSEREQGY---IIGDVSGKKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGL 257
Cdd:PRK03092 161 RVAEQWADRLgGAPLAFIHKTRDPTVPNQVVanrVVGDVEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVIIAATHGV 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489079890 258 FAGGAAEVLETAPIKEIIVTDSVK-TKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQP 320
Cdd:PRK03092 241 LSGPAAERLKNCGAREVVVTDTLPiPEEKRFDKLTVLSIAPLLARAIREVFEDGSVTSLFDGLA 304
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
12-320 |
3.48e-88 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 270.98 E-value: 3.48e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 12 LFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTV 91
Cdd:PTZ00145 122 LFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRASAKKI 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 92 NIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFD--IPVDNLFTVPLFAERYSKLGLSGS 169
Cdd:PTZ00145 202 TAVIPYYGYARQDRKLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGprVPVDNLEAQLIGLDYFTKKDLYKP 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 170 dvVVVSPKNSGIKRARSLAEYL------DSPIA-IIDYAQDDSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILE 242
Cdd:PTZ00145 282 --VIVSPDAGGVYRARKFQDGLnhrgisDCGIAmLIKQRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSGTLCEAAKQLK 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 243 RSGATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVKTKNRVPE--NVTYLSASDLIAEAIIRIHERRPLSPLFSYQP 320
Cdd:PTZ00145 360 KHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSNKNIDSckKITKLSVSVLVADAIRRIHQKESLNDLFNVKG 439
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
8-316 |
2.75e-87 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 264.87 E-value: 2.75e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 8 KQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRAS 87
Cdd:PRK04923 5 RNLLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 88 ANTVNIVLPYFGYSRQD-RVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVP-LFAERYSKLG 165
Cdd:PRK04923 85 AASVTAVIPYFGYSRQDrRMRSSRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPlLLADIWRAYG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 166 LsgSDVVVVSPKNSGIKRARSLAEYL-DSPIAIIDYAQDDSEREQGY-IIGDVSGKKAILIDDILNTGKTFAEAAKILER 243
Cdd:PRK04923 165 T--DNLIVVSPDVGGVVRARAVAKRLdDADLAIIDKRRPRANVATVMnIIGDVQGKTCVLVDDLVDTAGTLCAAAAALKQ 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489079890 244 SGATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSV--KTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLF 316
Cdd:PRK04923 243 RGALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIplSEAARACAKIRQLSVAELLAETIRRIAFGESVSSLY 317
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
12-288 |
2.47e-83 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 255.23 E-value: 2.47e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 12 LFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTV 91
Cdd:PRK00553 12 IFSLSKAKKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIAIDALKRGSAKSI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 92 NIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLgLSGSDV 171
Cdd:PRK00553 92 TAILPYYGYARQDRKTAGREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLSRVLEL-LGKKDL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 172 VVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSE-REQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSGATDTY 250
Cdd:PRK00553 171 VVVSPDYGGVKRARLIAESLELPLAIIDKRRPKHNvAESINVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQKAKKVC 250
|
250 260 270
....*....|....*....|....*....|....*...
gi 489079890 251 AVASHGLFAGGAAEVLETAPIKEIIvtDSVKTKNRVPE 288
Cdd:PRK00553 251 VMATHGLFNKNAIQLFDEAFKKKLI--DKLFVSNSIPQ 286
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
10-126 |
1.15e-70 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 214.98 E-value: 1.15e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 10 IKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASAN 89
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 489079890 90 TVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAG 126
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKPREPITAKLVADLLEAAG 117
|
|
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
21-303 |
1.30e-67 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 213.24 E-value: 1.30e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 21 IAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTsFPVNDNLWELLIMIDACKRASANTVNIVLPYFGY 100
Cdd:PRK00934 11 LASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIISTT-YPQDENLVELLLLIDALRDEGAKSITLVIPYLGY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 101 SRQDRVAKPREPITAKLVANMLTKAGiDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAErYSKLGLsgSDVVVVSPKNSG 180
Cdd:PRK00934 90 ARQDKRFKPGEPISARAIAKIISAYY-DRIITINIHEPSILEFFPIPFINLDAAPLIAE-YIGDKL--DDPLVLAPDKGA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 181 IKRARSLAEYLDspiaiIDYAQDDSEREQGYIIG------DVSGKKAILIDDILNTGKTFAEAAKILERSGATDTYAVAS 254
Cdd:PRK00934 166 LELAKEAAEILG-----CEYDYLEKTRISPTEVEiapknlDVKGKDVLIVDDIISTGGTMATAIKILKEQGAKKVYVACV 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 489079890 255 HGLFAGGAAEVLETAPIKEIIVTDSVKTKnrvpenVTYLSASDLIAEAI 303
Cdd:PRK00934 241 HPVLVGDAILKLYNAGVDEIIVTDTLESE------VSKISVAPLIADLL 283
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
9-305 |
3.62e-43 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 150.47 E-value: 3.62e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 9 QIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPvNDNLWELLIMIDACKRASA 88
Cdd:PRK07199 2 QPLLLALPGNEAAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLDRP-DEKLLPLLFAAEAARELGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 89 NTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTkAGIDRVVTLD--LHAV-QVQGFFDIPVDNLFTVPLFAerySKLG 165
Cdd:PRK07199 81 RRVGLVAPYLAYMRQDIAFHPGEAISQRHFARLLS-GSFDRLVTVDphLHRYpSLSEVYPIPAVVLSAAPAIA---AWIR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 166 LSGSDVVVVSPKNSGIKRARSLAEYLDSPIAI----------IDYAQDDSEReqgyiigdVSGKKAILIDDILNTGKTFA 235
Cdd:PRK07199 157 AHVPRPLLIGPDEESEQWVAAVAERAGAPHAVlrktrhgdrdVEISLPDAAP--------WAGRTPVLVDDIVSTGRTLI 228
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489079890 236 EAAKILERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVK-TKNRVpenvtylSASDLIAEAIIR 305
Cdd:PRK07199 229 EAARQLRAAGAASPDCVVVHALFAGDAYSALAAAGIARVVSTDTVPhPSNAI-------SLAPLLAEALRR 292
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
41-315 |
6.56e-39 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 141.24 E-value: 6.56e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 41 FSDGEIMINIEETVRGDDIYIIQSTS--------------FPVNDNLWELLIMIDACkRASANTVNIVLPYFGYSRQDRv 106
Cdd:PRK06827 62 FSNGEAKGEILESVRGKDIYILQDVGnysvtynmfgeknhMSPDDHFQDLKRTIDAI-RGKARRITVIMPFLYESRQHK- 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 107 AKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIP-VDNLFT----VPLFAERYSKLGLSGSDVVVVSPKNSGI 181
Cdd:PRK06827 140 RKGRESLDCALALQELEELGVDNIITFDAHDPRIENAIPLMgFENLYPsyqiIKALLKNEKDLEIDKDHLMVISPDTGAM 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 182 KRARSLAEYLDSPIAII----DYAQDDSER----EQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSGATDTYAVA 253
Cdd:PRK06827 220 DRAKYYASVLGVDLGLFykrrDYSRVVNGRnpivAHEFLGRDVEGKDVLIVDDMIASGGSMIDAAKELKSRGAKKIIVAA 299
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489079890 254 SHGLFAGGAA---EVLETAPIKEIIVTDSVKTKNRVPENVTYLSA--SDLIAEAIIRIHERRPLSPL 315
Cdd:PRK06827 300 TFGFFTNGLEkfdKAYEEGYFDRIIGTNLVYHPEELLSKPWYIEVdmSKLIARIIDALNHDVSLSKL 366
|
|
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
172-316 |
1.32e-22 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 92.96 E-value: 1.32e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 172 VVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQG-------------------------------YIIGDVSGKK 220
Cdd:pfam14572 6 VIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVdgrqspppyrsrtvsrslglpeiipkekppmTVVGDVGGRI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 221 AILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVKTKNRVPE--NVTYLSASDL 298
Cdd:pfam14572 86 AIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQchKIKTIDISQL 165
|
170
....*....|....*...
gi 489079890 299 IAEAIIRIHERRPLSPLF 316
Cdd:pfam14572 166 IAEAIRRIHNGESMSYLF 183
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
154-279 |
3.68e-20 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 84.75 E-value: 3.68e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 154 VPLFAERYSKLGlsGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQG-------YIIGDVSGKKAILIDD 226
Cdd:cd06223 2 GRLLAEEIREDL--LEPDVVVGILRGGLPLAAALARALGLPLAFIRKERKGPGRTPSepyglelPLGGDVKGKRVLLVDD 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 489079890 227 ILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAAEvlETAPIKEIIVTDS 279
Cdd:cd06223 80 VIATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGARE--LASPGDPVYSLFT 130
|
|
| PLN02297 |
PLN02297 |
ribose-phosphate pyrophosphokinase |
8-303 |
5.33e-20 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 177934 [Multi-domain] Cd Length: 326 Bit Score: 88.59 E-value: 5.33e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 8 KQIKLFSLTSNLPIAEKIAKAAG-IPLGKMSSRQFSDG--EIMINIEETVRGDDIYIIqsTSFPVNDNLWELLIMIDACK 84
Cdd:PLN02297 15 KQVHLFYCEETEELARKIAAESDaIELGSINWRKFPDGfpNLFINNAHGIRGQHVAFL--ASFSSPAVIFEQLSVIYALP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 85 RASANTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDR-----VVTLDLHAVQVQGFFDIPVDNLFT--VPLF 157
Cdd:PLN02297 93 KLFVASFTLVLPFFPTGTSERVEREGDVATAFTLARILSNIPISRggptsLVIFDIHALQERFYFGDNVLPCFEsgIPLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 158 AERYSKLglSGSDVVVVS-PKNSGIKRARSLAEylDSPIAIIDYAQDDSEReqgyII----GDVSGKKAILIDDILNTGK 232
Cdd:PLN02297 173 KKRLQQL--PDSDNIVIAfPDDGAWKRFHKQFE--HFPMVVCTKVREGDKR----IVrikeGNPAGRHVVIVDDLVQSGG 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 233 TFAEAAKILERSGATDTYAVASHGLF-----------AGGAAEVLEtapikEIIVTDS----VK-TKNRVPENVtyLSAS 296
Cdd:PLN02297 245 TLIECQKVLAAHGAAKVSAYVTHGVFpneswerfthdNGGPEAGFA-----YFWITDScpqtVKaVRGKAPFEV--LSLA 317
|
....*..
gi 489079890 297 DLIAEAI 303
Cdd:PLN02297 318 GSIADAL 324
|
|
| Pribosyltran |
pfam00156 |
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ... |
156-275 |
3.37e-07 |
|
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.
Pssm-ID: 425489 [Multi-domain] Cd Length: 150 Bit Score: 48.90 E-value: 3.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 156 LFAERYSKLGlsGSDVVVVSPKNSGIKRARSLAEYLDSPIAIID---YAQDDSErEQGYI--IGDVSGKKAILIDDILNT 230
Cdd:pfam00156 18 LAAQINEDYG--GKPDVVVGILRGGLPFAGILARRLDVPLAFVRkvsYNPDTSE-VMKTSsaLPDLKGKTVLIVDDILDT 94
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 489079890 231 GKTFAEAAKILERSGATDtyaVASHGLFAGGAAEVLETAPIKEII 275
Cdd:pfam00156 95 GGTLLKVLELLKNVGPKE---VKIAVLIDKPAGTEPKDKYDKRVD 136
|
|
| ComFC |
COG1040 |
DNA utilization protein ComFC/GntX, contains phosphoribosyltransferase domain [General ... |
214-253 |
4.82e-06 |
|
DNA utilization protein ComFC/GntX, contains phosphoribosyltransferase domain [General function prediction only];
Pssm-ID: 440662 [Multi-domain] Cd Length: 196 Bit Score: 46.35 E-value: 4.82e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 489079890 214 GDVSGKKAILIDDILNTGKTFAEAAKILERSGATDTYAVA 253
Cdd:COG1040 151 ARLAGKHVLLVDDVLTTGATLAEAARALKAAGAARVDVLV 190
|
|
| Hpt1 |
COG2236 |
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine ... |
170-248 |
1.11e-05 |
|
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage
Pssm-ID: 441837 [Multi-domain] Cd Length: 153 Bit Score: 44.84 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 170 DVVVvspknsGIKR-----ARSLAEYLD----SPIAIIDYAQDDSERE----QGYIIGDVSGKKAILIDDILNTGKTFAE 236
Cdd:COG2236 33 DVIV------AIARgglvpARILADALGvpdlASIRVSSYTGTAKRLEepvvKGPLDEDLAGKRVLIVDDVADTGRTLEA 106
|
90
....*....|..
gi 489079890 237 AAKILERSGATD 248
Cdd:COG2236 107 VRDLLKEAGPAE 118
|
|
| PRK02277 |
PRK02277 |
orotate phosphoribosyltransferase-like protein; Provisional |
172-247 |
5.79e-05 |
|
orotate phosphoribosyltransferase-like protein; Provisional
Pssm-ID: 235023 [Multi-domain] Cd Length: 200 Bit Score: 43.32 E-value: 5.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 172 VVVSPKNSGIKRARSLAEYLDSPIAII---DYAQDDSEREQGYI---IGDVSGKKAILIDDILNTGKTFAEAAKILERSG 245
Cdd:PRK02277 88 VVVGIAKSGVPLATLVADELGKDLAIYhpkKWDHGEGEKKTGSFsrnFASVEGKRCVIVDDVITSGTTMKETIEYLKEHG 167
|
..
gi 489079890 246 AT 247
Cdd:PRK02277 168 GK 169
|
|
| PyrE |
COG0461 |
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate ... |
208-272 |
1.65e-04 |
|
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440229 Cd Length: 201 Bit Score: 42.06 E-value: 1.65e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489079890 208 EQGYIIGDV-SGKKAILIDDILNTGKTFAEAAKILERSGATDTYAVAshgLF--AGGAAEVLETAPIK 272
Cdd:COG0461 101 TGGQIEGGLlPGERVLVVEDVITTGGSVLEAVEALREAGAEVVGVAV---IVdrEEGAAENLEEAGVP 165
|
|
| pyrE |
PRK00455 |
orotate phosphoribosyltransferase; Validated |
150-272 |
4.48e-04 |
|
orotate phosphoribosyltransferase; Validated
Pssm-ID: 234771 Cd Length: 202 Bit Score: 40.53 E-value: 4.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 150 NLFTVPLFAERYSKLGL--------SGSDV-VVVSPKNSGIKRARSLAEYLDSPIAIIdyaqddsERE------QGYIIG 214
Cdd:PRK00455 36 DCRKLLSYPEALALLGRflaeaikdSGIEFdVVAGPATGGIPLAAAVARALDLPAIFV-------RKEakdhgeGGQIEG 108
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489079890 215 -DVSGKKAILIDDILNTGKTFAEAAKILERSGATdtyaVAshGLFA-----GGAAEVLETAPIK 272
Cdd:PRK00455 109 rRLFGKRVLVVEDVITTGGSVLEAVEAIRAAGAE----VV--GVAVivdrqSAAQEVFADAGVP 166
|
|
| PRK11595 |
PRK11595 |
DNA utilization protein GntX; Provisional |
148-246 |
1.05e-03 |
|
DNA utilization protein GntX; Provisional
Pssm-ID: 183221 [Multi-domain] Cd Length: 227 Bit Score: 40.02 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 148 VDNLFTVPLFAERYSKLGLSGSDVVvvspknsgikrARSLAEYLDSpiaiiDYAQDDSER------EQGY---------- 211
Cdd:PRK11595 113 PDRIISVPLHQRRHWRRGFNQSDLL-----------CRPLARWLGC-----DYDSEALTRtratatQHFLsarlrkrnlk 176
|
90 100 110
....*....|....*....|....*....|....*....
gi 489079890 212 ----IIGDVSGKKAILIDDILNTGKTFAEAAKILERSGA 246
Cdd:PRK11595 177 nafrLELPVQGQHMAIVDDVVTTGSTVAEIAQLLLRNGA 215
|
|
| ComA-like_MBL-fold |
cd07731 |
Competence protein ComA, ComEC and related proteins; MBL-fold metallo hydrolase domain; This ... |
217-308 |
5.69e-03 |
|
Competence protein ComA, ComEC and related proteins; MBL-fold metallo hydrolase domain; This subgroup includes proteins required for natural transformation competence including Neisseria gonorrhoeae ComA, Pseudomonas stutzeri ComA, Bacillus subtilis ComEC (also known as ComE operon protein 3) and Haemophilus influenza ORF2 encoded by the rec-2 gene, as well as Escherichia coli YcaI which does not mediate spontaneous plasmid transformation on nutrient-containing agar plates. It also includes the phosphorylcholine esterase (Pce) domain of choline-binding protein e from streptococcus pneumonia. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.
Pssm-ID: 293817 [Multi-domain] Cd Length: 179 Bit Score: 37.11 E-value: 5.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079890 217 SGKKAILIDdilnTGKTFAEAAKI----LERSGATD-TYAVASHGLF--AGGAAEVLETAPIKEIIVTDSVKTknrvpeN 289
Cdd:cd07731 17 TPGKTILID----TGPRDSFGEDVvvpyLKARGIKKlDYLILTHPDAdhIGGLDAVLKNFPVKEVYMPGVTHT------T 86
|
90
....*....|....*....
gi 489079890 290 VTYLSASDLIAEAIIRIHE 308
Cdd:cd07731 87 KTYEDLLDAIKEKGIPVTP 105
|
|
| |
