|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12830 |
PRK12830 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed |
1-419 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed
Pssm-ID: 183779 Cd Length: 417 Bit Score: 740.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 1 MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQD 80
Cdd:PRK12830 1 MEKIVINGGKPLSGEVTISGAKNSAVALIPAAILADGPVTLDGVPDISDVHSLVDILEELGGKVKRDGDTLEIDPTGIQS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 81 IPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNgqKIHGAHIYM 160
Cdd:PRK12830 81 MPLPNGKVKSLRASYYFMGALLGRFKKAVVGLPGGCDLGPRPIDQHIKGFEALGAEVTNEGGAIYLKAD--ELKGAHIYL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 161 DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTY 240
Cdd:PRK12830 159 DVVSVGATINIMLAAVKAKGRTVIENAAKEPEIIDVATLLNNMGANIKGAGTDVIRIEGVDELHGCRHTVIPDRIEAGTY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 241 IALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADG 320
Cdd:PRK12830 239 MILAAACGGGVTINNVIPEHLESFIAKLEEMGVRVEVNEDSIFVEKQGNLKAVDIKTLPYPGFATDLQQPLTPLLLKANG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 321 RGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGY 400
Cdd:PRK12830 319 RSVVTDTIYEKRFKHVDELKRMGANIKVEGRSAIITGPSKLTGAKVKATDLRAGAALVIAGLMAEGVTEITNIEHIDRGY 398
|
410
....*....|....*....
gi 489079357 401 ASIIAKLTALGADIQLIED 419
Cdd:PRK12830 399 SNIIEKLKALGADIWREED 417
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
1-417 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 598.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 1 MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYH-GDTLEIDPRGVQ 79
Cdd:COG0766 1 MDKLIIEGGKPLSGEVRISGAKNAALPILAAALLTDGPVTLRNVPDLSDVRTMLELLESLGVKVERDdGGTLTIDASNIN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 80 DIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGqkIHGAHIY 159
Cdd:COG0766 81 STEAPYELVRKMRASILVLGPLLARFGEARVSLPGGCAIGARPIDLHLKGLEALGAEIEIEHGYIEARAGR--LKGARIY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 160 MDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGT 239
Cdd:COG0766 159 LDFPSVGATENIMMAAVLAEGTTVIENAAREPEIVDLANFLNAMGAKIEGAGTDTITIEGVEKLHGAEHTVIPDRIEAGT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 240 YIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKAD 319
Cdd:COG0766 239 FLVAAAITGGDVTVKNVIPEHLEAVLAKLREAGVEIEEGDDGIRVRGPGRLKAVDIKTAPYPGFPTDLQAQFMALLTQAE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 320 GRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRG 399
Cdd:COG0766 319 GTSVITETVFENRFMHVDELNRMGADIKLDGHTAIVRGVTKLSGAPVMATDLRAGAALVLAGLAAEGETVIDNIYHIDRG 398
|
410
....*....|....*...
gi 489079357 400 YASIIAKLTALGADIQLI 417
Cdd:COG0766 399 YENLEEKLRALGADIERV 416
|
|
| UdpNAET |
cd01555 |
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the ... |
12-410 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.
Pssm-ID: 238796 Cd Length: 400 Bit Score: 547.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 12 LSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHG-DTLEIDPRGVQDIPMPYGKINS 90
Cdd:cd01555 1 LSGEVRISGAKNAALPILAAALLTDEPVTLRNVPDLLDVETMIELLRSLGAKVEFEGeNTLVIDASNINSTEAPYELVRK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 91 LRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGqKIHGAHIYMDTVSVGATIN 170
Cdd:cd01555 81 MRASILVLGPLLARFGEARVSLPGGCAIGARPVDLHLKGLEALGAKIEIEDGYVEAKAAG-RLKGARIYLDFPSVGATEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 171 TMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKG 250
Cdd:cd01555 160 IMMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKIEGAGTDTIRIEGVERLHGAEHTVIPDRIEAGTFLVAAAITGGD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 251 VKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVE-KQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIY 329
Cdd:cd01555 240 ITVENVIPEHLEAVLAKLREMGAKIEIGEDGIRVDgDGGRLKAVDIETAPYPGFPTDLQAQFMALLTQAEGTSVITETIF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 330 EKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGYASIIAKLTA 409
Cdd:cd01555 320 ENRFMHVDELNRMGADIKVEGNTAIIRGVTKLSGAPVMATDLRAGAALVLAGLAAEGETIISNIYHIDRGYERIEEKLRA 399
|
.
gi 489079357 410 L 410
Cdd:cd01555 400 L 400
|
|
| murA |
TIGR01072 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and ... |
1-415 |
3.74e-174 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 162190 [Multi-domain] Cd Length: 416 Bit Score: 492.90 E-value: 3.74e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 1 MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQD 80
Cdd:TIGR01072 1 MDKLVVEGGKPLSGEVTISGAKNAALPIIAATLLTDEPVTLTNVPDLSDVKTTLDLLRNLGARVERDNNTLEINTPNINS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 81 IPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGqKIHGAHIYM 160
Cdd:TIGR01072 81 TEAPYELVRKMRASILVLGPLLARFGKAVVSLPGGCAIGARPVDLHLKGLKALGAEIVIEDGYVYASAKG-RLVGAHIVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 161 DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTY 240
Cdd:TIGR01072 160 DKVSVGATENIIMAAVLAEGTTVIENAAREPEIVDLCEFLNKMGAKITGAGSNTITIEGVEKLHGTEHSVIPDRIEAGTF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 241 IALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVE-KQESLKAITIKTSPYPGFATDLQQPLTPLLLKAD 319
Cdd:TIGR01072 240 LVAAAITGGEITIKNVRPDHLRAVLAKLREIGAEVEVDENGIRVDmRQKRLKAVDIETLPYPGFPTDLQAQFMALLSQAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 320 GRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRG 399
Cdd:TIGR01072 320 GTSVITETVFENRFMHVDELIRMGANIKLEGNTAVIHGVEQLSGAEVMATDLRAGAALVLAGLVAEGETIVHNVYHLDRG 399
|
410
....*....|....*.
gi 489079357 400 YASIIAKLTALGADIQ 415
Cdd:TIGR01072 400 YEDLEEKLRALGAKIE 415
|
|
| EPSP_synthase |
pfam00275 |
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); |
7-407 |
1.07e-87 |
|
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
Pssm-ID: 395213 Cd Length: 415 Bit Score: 272.25 E-value: 1.07e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 7 NGGKALSGEVAVSG-AKNSVVALIPAIILADDIVIlDGVPAISDVDSLIEIMELMGATVNYHGDTLE--IDPRGVQDIPM 83
Cdd:pfam00275 1 TGGSRLSGEVKIPGsKSNSHRALILAALAAGESTI-TNLLDSDDTLTMLEALRALGAEIIKLDDEKSvvIVEGLGGSFEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 84 PYGKINSLRASYYFYGSLLGRFGQAV--VGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLS--TNGQKIHGAHIY 159
Cdd:pfam00275 80 PEDLVLDMGNSGTALRPLTGRLALQSgeVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREGYNYAPlkVRGLRLGGIHID 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 160 MDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTD-IITIQGVQKLHGTRHQVIPDRIEAG 238
Cdd:pfam00275 160 GDVSSQFVTSLLMLAALLAEGTTTIENLASEPYIDDTENMLKKFGAKIEGSGTElSITVKGGEKLPGQEYRVEGDRSSAA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 239 TYIALAAAIGKGVKITNVLYEHL---ESFIAKLEEMGVRMTVEEDAIFVEKQ--ESLKAITIKTSPYPGFATDLQQPLTP 313
Cdd:pfam00275 240 YFLVAAAITGGTVTVENVGINSLqgdEALLEILEKMGAEITQEEDADIVVGPpgLRGKAVDIRTAPDPAPTTAVLAAFAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 314 LLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIG-GQIVYQGPSRLTGAQVKAT-DLRAGAALVTAGLIAEGKTEIT 391
Cdd:pfam00275 320 GTTRIEGISELRVKETDRLFAMATELRRLGADVEELPdGLIIIPAVKELKGAEVDSYgDHRIAMALALAGLVAEGETIID 399
|
410
....*....|....*.
gi 489079357 392 NIEFILRGYASIIAKL 407
Cdd:pfam00275 400 DIECTDRSFPDFEEKL 415
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12830 |
PRK12830 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed |
1-419 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed
Pssm-ID: 183779 Cd Length: 417 Bit Score: 740.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 1 MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQD 80
Cdd:PRK12830 1 MEKIVINGGKPLSGEVTISGAKNSAVALIPAAILADGPVTLDGVPDISDVHSLVDILEELGGKVKRDGDTLEIDPTGIQS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 81 IPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNgqKIHGAHIYM 160
Cdd:PRK12830 81 MPLPNGKVKSLRASYYFMGALLGRFKKAVVGLPGGCDLGPRPIDQHIKGFEALGAEVTNEGGAIYLKAD--ELKGAHIYL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 161 DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTY 240
Cdd:PRK12830 159 DVVSVGATINIMLAAVKAKGRTVIENAAKEPEIIDVATLLNNMGANIKGAGTDVIRIEGVDELHGCRHTVIPDRIEAGTY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 241 IALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADG 320
Cdd:PRK12830 239 MILAAACGGGVTINNVIPEHLESFIAKLEEMGVRVEVNEDSIFVEKQGNLKAVDIKTLPYPGFATDLQQPLTPLLLKANG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 321 RGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGY 400
Cdd:PRK12830 319 RSVVTDTIYEKRFKHVDELKRMGANIKVEGRSAIITGPSKLTGAKVKATDLRAGAALVIAGLMAEGVTEITNIEHIDRGY 398
|
410
....*....|....*....
gi 489079357 401 ASIIAKLTALGADIQLIED 419
Cdd:PRK12830 399 SNIIEKLKALGADIWREED 417
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
1-417 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 598.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 1 MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYH-GDTLEIDPRGVQ 79
Cdd:COG0766 1 MDKLIIEGGKPLSGEVRISGAKNAALPILAAALLTDGPVTLRNVPDLSDVRTMLELLESLGVKVERDdGGTLTIDASNIN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 80 DIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGqkIHGAHIY 159
Cdd:COG0766 81 STEAPYELVRKMRASILVLGPLLARFGEARVSLPGGCAIGARPIDLHLKGLEALGAEIEIEHGYIEARAGR--LKGARIY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 160 MDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGT 239
Cdd:COG0766 159 LDFPSVGATENIMMAAVLAEGTTVIENAAREPEIVDLANFLNAMGAKIEGAGTDTITIEGVEKLHGAEHTVIPDRIEAGT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 240 YIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKAD 319
Cdd:COG0766 239 FLVAAAITGGDVTVKNVIPEHLEAVLAKLREAGVEIEEGDDGIRVRGPGRLKAVDIKTAPYPGFPTDLQAQFMALLTQAE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 320 GRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRG 399
Cdd:COG0766 319 GTSVITETVFENRFMHVDELNRMGADIKLDGHTAIVRGVTKLSGAPVMATDLRAGAALVLAGLAAEGETVIDNIYHIDRG 398
|
410
....*....|....*...
gi 489079357 400 YASIIAKLTALGADIQLI 417
Cdd:COG0766 399 YENLEEKLRALGADIERV 416
|
|
| PRK09369 |
PRK09369 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated |
1-417 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated
Pssm-ID: 236486 Cd Length: 417 Bit Score: 571.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 1 MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGD-TLEIDPRGVQ 79
Cdd:PRK09369 1 MDKLVIEGGKPLSGEVTISGAKNAALPILAASLLAEEPVTLTNVPDLSDVRTMIELLRSLGAKVEFDGNgTVTIDASNIN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 80 DIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGqKIHGAHIY 159
Cdd:PRK09369 81 NTEAPYELVKKMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDLHLKGLEALGAEIEIEHGYVEAKADG-RLKGAHIV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 160 MDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGT 239
Cdd:PRK09369 160 LDFPSVGATENILMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKISGAGTDTITIEGVERLHGAEHTVIPDRIEAGT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 240 YIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKAD 319
Cdd:PRK09369 240 FLVAAAITGGDVTIRGARPEHLEAVLAKLREAGAEIEEGEDGIRVDMPGRLKAVDIKTAPYPGFPTDMQAQFMALLTQAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 320 GRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRG 399
Cdd:PRK09369 320 GTSVITETIFENRFMHVPELIRMGADIEVDGHTAVVRGVEKLSGAPVMATDLRASASLVLAGLVAEGTTIVDRIYHLDRG 399
|
410
....*....|....*...
gi 489079357 400 YASIIAKLTALGADIQLI 417
Cdd:PRK09369 400 YERIEEKLRALGADIERV 417
|
|
| UdpNAET |
cd01555 |
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the ... |
12-410 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.
Pssm-ID: 238796 Cd Length: 400 Bit Score: 547.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 12 LSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHG-DTLEIDPRGVQDIPMPYGKINS 90
Cdd:cd01555 1 LSGEVRISGAKNAALPILAAALLTDEPVTLRNVPDLLDVETMIELLRSLGAKVEFEGeNTLVIDASNINSTEAPYELVRK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 91 LRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGqKIHGAHIYMDTVSVGATIN 170
Cdd:cd01555 81 MRASILVLGPLLARFGEARVSLPGGCAIGARPVDLHLKGLEALGAKIEIEDGYVEAKAAG-RLKGARIYLDFPSVGATEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 171 TMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKG 250
Cdd:cd01555 160 IMMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKIEGAGTDTIRIEGVERLHGAEHTVIPDRIEAGTFLVAAAITGGD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 251 VKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVE-KQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIY 329
Cdd:cd01555 240 ITVENVIPEHLEAVLAKLREMGAKIEIGEDGIRVDgDGGRLKAVDIETAPYPGFPTDLQAQFMALLTQAEGTSVITETIF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 330 EKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGYASIIAKLTA 409
Cdd:cd01555 320 ENRFMHVDELNRMGADIKVEGNTAIIRGVTKLSGAPVMATDLRAGAALVLAGLAAEGETIISNIYHIDRGYERIEEKLRA 399
|
.
gi 489079357 410 L 410
Cdd:cd01555 400 L 400
|
|
| murA |
TIGR01072 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and ... |
1-415 |
3.74e-174 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 162190 [Multi-domain] Cd Length: 416 Bit Score: 492.90 E-value: 3.74e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 1 MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQD 80
Cdd:TIGR01072 1 MDKLVVEGGKPLSGEVTISGAKNAALPIIAATLLTDEPVTLTNVPDLSDVKTTLDLLRNLGARVERDNNTLEINTPNINS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 81 IPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGqKIHGAHIYM 160
Cdd:TIGR01072 81 TEAPYELVRKMRASILVLGPLLARFGKAVVSLPGGCAIGARPVDLHLKGLKALGAEIVIEDGYVYASAKG-RLVGAHIVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 161 DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTY 240
Cdd:TIGR01072 160 DKVSVGATENIIMAAVLAEGTTVIENAAREPEIVDLCEFLNKMGAKITGAGSNTITIEGVEKLHGTEHSVIPDRIEAGTF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 241 IALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVE-KQESLKAITIKTSPYPGFATDLQQPLTPLLLKAD 319
Cdd:TIGR01072 240 LVAAAITGGEITIKNVRPDHLRAVLAKLREIGAEVEVDENGIRVDmRQKRLKAVDIETLPYPGFPTDLQAQFMALLSQAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 320 GRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRG 399
Cdd:TIGR01072 320 GTSVITETVFENRFMHVDELIRMGANIKLEGNTAVIHGVEQLSGAEVMATDLRAGAALVLAGLVAEGETIVHNVYHLDRG 399
|
410
....*....|....*.
gi 489079357 400 YASIIAKLTALGADIQ 415
Cdd:TIGR01072 400 YEDLEEKLRALGAKIE 415
|
|
| EPSP_synthase |
pfam00275 |
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); |
7-407 |
1.07e-87 |
|
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
Pssm-ID: 395213 Cd Length: 415 Bit Score: 272.25 E-value: 1.07e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 7 NGGKALSGEVAVSG-AKNSVVALIPAIILADDIVIlDGVPAISDVDSLIEIMELMGATVNYHGDTLE--IDPRGVQDIPM 83
Cdd:pfam00275 1 TGGSRLSGEVKIPGsKSNSHRALILAALAAGESTI-TNLLDSDDTLTMLEALRALGAEIIKLDDEKSvvIVEGLGGSFEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 84 PYGKINSLRASYYFYGSLLGRFGQAV--VGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLS--TNGQKIHGAHIY 159
Cdd:pfam00275 80 PEDLVLDMGNSGTALRPLTGRLALQSgeVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREGYNYAPlkVRGLRLGGIHID 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 160 MDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTD-IITIQGVQKLHGTRHQVIPDRIEAG 238
Cdd:pfam00275 160 GDVSSQFVTSLLMLAALLAEGTTTIENLASEPYIDDTENMLKKFGAKIEGSGTElSITVKGGEKLPGQEYRVEGDRSSAA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 239 TYIALAAAIGKGVKITNVLYEHL---ESFIAKLEEMGVRMTVEEDAIFVEKQ--ESLKAITIKTSPYPGFATDLQQPLTP 313
Cdd:pfam00275 240 YFLVAAAITGGTVTVENVGINSLqgdEALLEILEKMGAEITQEEDADIVVGPpgLRGKAVDIRTAPDPAPTTAVLAAFAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 314 LLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIG-GQIVYQGPSRLTGAQVKAT-DLRAGAALVTAGLIAEGKTEIT 391
Cdd:pfam00275 320 GTTRIEGISELRVKETDRLFAMATELRRLGADVEELPdGLIIIPAVKELKGAEVDSYgDHRIAMALALAGLVAEGETIID 399
|
410
....*....|....*.
gi 489079357 392 NIEFILRGYASIIAKL 407
Cdd:pfam00275 400 DIECTDRSFPDFEEKL 415
|
|
| EPT-like |
cd01554 |
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine ... |
12-410 |
1.72e-77 |
|
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer.
Pssm-ID: 238795 Cd Length: 408 Bit Score: 245.98 E-value: 1.72e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 12 LSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGV---QDIPMPYGKI 88
Cdd:cd01554 1 LHGIIRVPGDKSISHRSLIFASLAEGETKVYNILRGEDVLSTMQVLRDLGVEIEDKDGVITIQGVGMaglKAPQNALNLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 89 NSLRASYYFYGSLLGRFGQavVGLPGGCDLGPRPIDLHLKAFEAMGVEVSY-EGENMNLSTNGQKIHGAHIYMD-TVSVG 166
Cdd:cd01554 81 NSGTAIRLISGVLAGADFE--VELFGDDSLSKRPMDRVTLPLKKMGASISGqEERDLPPLLKGGKNLGPIHYEDpIASAQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 167 ATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAA 246
Cdd:cd01554 159 VKSALMFAALLAKGETVIIEAAKEPTINHTENMLQTFGGHISVQGTKKIVVQGPQKLTGQKYVVPGDISSAAFFLVAAAI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 247 IGKGVKITNV-LYEHLESFIAKLEEMGVRMTVEEDAIFVEKQEsLKAITIKTSPYPgFATDLQQPLTPLLLKADGRGTII 325
Cdd:cd01554 239 APGRLVLQNVgINETRTGIIDVLRAMGAKIEIGEDTISVESSD-LKATEICGALIP-RLIDELPIIALLALQAQGTTVIK 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 326 DTIY------EKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKAT-DLRAGAALVTAGLIAEGKTEITNIEFILR 398
Cdd:cd01554 317 DAEElkvketDRIFVVADELNSMGADIEPTADGMIIKGKEKLHGARVNTFgDHRIGMMTALAALVADGEVELDRAEAINT 396
|
410
....*....|..
gi 489079357 399 GYASIIAKLTAL 410
Cdd:cd01554 397 SYPSFFDDLESL 408
|
|
| EPSP_synthase |
cd01556 |
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase ... |
12-396 |
1.56e-24 |
|
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshkimate-3-phosphate (EPSP), an intermediate in the shikimate pathway leading to aromatic amino acid biosynthesis. The reaction is phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. It is found in bacteria and plants but not animals. The enzyme is the target of the widely used herbicide glyphosate, which has been shown to occupy the active site. In bacteria and plants, it is a single domain protein, while in fungi, the domain is found as part of a multidomain protein with functions that are all part of the shikimate pathway.
Pssm-ID: 238797 Cd Length: 409 Bit Score: 104.56 E-value: 1.56e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 12 LSGEVAVSGAKN-SVVALIPAIiLADDIVILDGvPAIS-DVDSLIEIMELMGATVNYHGDTLEIDPRGVQdIPMPYGKI- 88
Cdd:cd01556 1 LSGEITVPGSKSiSHRALLLAA-LAEGESRIEN-LLDSdDTLATLEALRALGAKIEEEGGTVEIVGGGGL-GLPPEAVLd 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 89 --NSLRASYYFYGSLLGRFGQAVvgLPGGCDLGPRPIDLHLKAFEAMGVEVSY-EGENMNLSTNGQKIHGAHIYMDtVSV 165
Cdd:cd01556 78 cgNSGTTMRLLTGLLALQGGDSV--LTGDESLRKRPMGRLVDALRQLGAEIEGrEGGGYPPLIGGGGLKGGEVEIP-GAV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 166 GATINT--MVAATKAQGKTVIENAAREPEI-IDVaTL--LNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDrIEAGTY 240
Cdd:cd01556 155 SSQFKSalLLAAPLAEGPTTIIIGELESKPyIDH-TErmLRAFGAEVEVDGYRTITVKGGQKYKGPEYTVEGD-ASSAAF 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 241 IALAAAIGKG-VKITNVLYEHLESFIAK-LEEMGVRMTV-EEDAIFVEKQESLKAITIKTSPYPgfatDLQQPLTPLLLK 317
Cdd:cd01556 233 FLAAAAITGSeIVIKNVGLNSGDTGIIDvLKEMGADIEIgNEDTVVVESGGKLKGIDIDGNDIP----DEAPTLAVLAAF 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 318 ADGrGTIIDTIYEKRINH-------VPELMRMGADISVIG-GQIVYQGPSRLTGAQVKA-TDLRAGAALVTAGLIAEGKT 388
Cdd:cd01556 309 AEG-PTRIRNAAELRVKEsdriaamATELRKLGADVEETEdGLIIEGGPLKGAGVEVYTyGDHRIAMSFAIAGLVAEGGV 387
|
....*...
gi 489079357 389 EITNIEFI 396
Cdd:cd01556 388 TIEDPECV 395
|
|
| aroA |
TIGR01356 |
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents ... |
14-413 |
1.34e-22 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273574 Cd Length: 409 Bit Score: 98.89 E-value: 1.34e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 14 GEVAVSGAKN-SVVALIPAIiLADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQdipMPYGKIN--- 89
Cdd:TIGR01356 1 GEIRAPGSKSiTHRALILAA-LAEGETRVRNLLRSEDTLATLDALRALGAKIEDGGEVAVIEGVGGK---EPQAELDlgn 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 90 ---SLRasyyFYGSLLGRFGQAVVgLPGGCDLGPRPIDLHLKAFEAMGVEVSY--EGENMNLSTNGqKIHGAHIYMDTvS 164
Cdd:TIGR01356 77 sgtTAR----LLTGVLALADGEVV-LTGDESLRKRPMGRLVDALRQLGAEISSleGGGSLPLTISG-PLPGGIVYISG-S 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 165 VGATINT--MVAATKAQGKTVIENAAREPEIIDVATLLNNMGAH---IRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGT 239
Cdd:TIGR01356 150 ASSQYKSalLLAAPALQAVGITIVGEPLKSRPYIEITLDLLGSFgveVERSDGRKIVVPGGQKYGPQGYDVPGDYSSAAF 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 240 YIALAAAIGKGVKITNVLYEHLE---SFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPgfatDLQQPLTPLLL 316
Cdd:TIGR01356 230 FLAAAAITGGRVTLENLGINPTQgdkAIIIVLEEMGADIEVEEDDLIVEGASGLKGIKIDMDDMI----DELPTLAVLAA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 317 KADGRGTIIDtIYEKRINH-------VPELMRMGADISVIGGQIVYQGPSRLTGAQVKA-TDLRAGAALVTAGLIAEGKT 388
Cdd:TIGR01356 306 FAEGVTRITG-AEELRVKEsdriaaiAEELRKLGVDVEEFEDGLYIRGKKELKGAVVDTfGDHRIAMAFAVAGLVAEGEV 384
|
410 420
....*....|....*....|....*
gi 489079357 389 EITNIEFILRGYASIIAKLTALGAD 413
Cdd:TIGR01356 385 LIDDPECVAKSFPSFFDVLERLGAN 409
|
|
| AroA |
COG0128 |
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ... |
1-419 |
2.01e-18 |
|
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439898 Cd Length: 421 Bit Score: 86.68 E-value: 2.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 1 MRKIIINGGKALSGEVAVSGAKnSV---VALIPAiiLADDIVILDGVPAISDVDSLIEIMELMGATVNYH-GDTLEIDPR 76
Cdd:COG0128 1 MSSLTIAPPSPLKGTVRVPGSK-SIshrALLLAA--LAEGESTIRNLLESDDTLATLEALRALGAEIEELdGGTLRVTGV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 77 GVQdIPMPYGKI---NSlrasyyfyGSLLgRFGQAVVGLPGGC-----D--LGPRPIDLHLKAFEAMGVEVSYEGENMN- 145
Cdd:COG0128 78 GGG-LKEPDAVLdcgNS--------GTTM-RLLTGLLALQPGEvvltgDesLRKRPMGRLLDPLRQLGARIESRGGGYLp 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 146 LSTNGQKIHGAHIYMDTV-------SVgatintMVAATKAQGKTVIENAAREPEI--IDVaTL--LNNMGAHIRGAGTDI 214
Cdd:COG0128 148 LTIRGGPLKGGEYEIPGSassqfksAL------LLAGPLAEGGLEITVTGELESKpyRDH-TErmLRAFGVEVEVEGYRR 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 215 ITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLES---FIAKLEEMGVRMTVEEDAIFVEKQEsLK 291
Cdd:COG0128 221 FTVPGGQRYRPGDYTVPGDISSAAFFLAAAAITGSEVTVEGVGLNSTQGdtgILDILKEMGADIEIENDGITVRGSP-LK 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 292 AITIktspypgfatdlqqpltplllkaDGrgtiidtiyekriNHVPELMrmgadisviggqivyqgPsrltgaqvkatdl 371
Cdd:COG0128 300 GIDI-----------------------DL-------------SDIPDEA-----------------P------------- 313
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 489079357 372 ragaALVTAGLIAEGKTEITNIEfILRGY-----ASIIAKLTALGADIQLIED 419
Cdd:COG0128 314 ----TLAVLAAFAEGTTRIRGAA-ELRVKesdriAAMATELRKLGADVEETED 361
|
|
| PRK02427 |
PRK02427 |
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional |
1-419 |
3.94e-13 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 235037 [Multi-domain] Cd Length: 435 Bit Score: 70.56 E-value: 3.94e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 1 MRKIIINGGKALSGEVAVSGAKN-SVVALIPAIiLADDIVILDGvPAIS-DVDSLIEIMELMGATVnyHGDTLEIDPRGV 78
Cdd:PRK02427 2 MMMLLIIPPSPLSGTVRVPGSKSiSHRALLLAA-LAEGETTITN-LLRSeDTLATLNALRALGVEI--EDDEVVVEGVGG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 79 QDIPMPYGKIN------SLRasyyFYGSLLGRFGQAVVgLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGE-NMNLSTNGq 151
Cdd:PRK02427 78 GGLKEPEDVLDcgnsgtTMR----LLTGLLALQPGEVV-LTGDESLRKRPMGRLLDPLRQMGAKIEGRDEgYLPLTIRG- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 152 KIHGAHIYMDT-VS---VGATIntMVAATKAQGKTVIEnaAREPEI----IDV-ATLLNNMGAHIR---GAGTDIITIQG 219
Cdd:PRK02427 152 GKKGGPIEYDGpVSsqfVKSLL--LLAPLFAEGDTETT--VIEPLPsrphTEItLRMLRAFGVEVEnveGWGYRRIVIKG 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 220 VQKLHGTRHQVIPDrIEAGTYIALAAAIGKG--VKITNVLYEHL---ESFIAKLEEMGVRMTVEEDAIFVEKQESlkaIT 294
Cdd:PRK02427 228 GQRLRGQDITVPGD-PSSAAFFLAAAAITGGseVTITNVGLNSTqggKAIIDVLEKMGADIEIENEREGGEPVGD---IR 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 295 IKTSPYpgfatdlqqpltplllkadgRGTIIDtiyekrINHVPELMrmgadisviggqivyqgPsrltgaqvkatdlrag 374
Cdd:PRK02427 304 VRSSEL--------------------KGIDID------IPDIIDEA-----------------P---------------- 324
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 489079357 375 aALVTAGLIAEGKTEITNIEFiLRG-----YASIIAKLTALGADIQLIED 419
Cdd:PRK02427 325 -TLAVLAAFAEGTTVIRNAEE-LRVketdrIAAMATELRKLGAEVEETED 372
|
|
| AroA |
COG0128 |
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ... |
4-256 |
1.84e-08 |
|
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439898 Cd Length: 421 Bit Score: 55.86 E-value: 1.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 4 IIINGGKALSGEVAVSGAKNSVV--ALIPAIILADD---IVILDGVPAISDVDSLIEIMELMGATVNYHG-DTLEIDPRG 77
Cdd:COG0128 148 LTIRGGPLKGGEYEIPGSASSQFksALLLAGPLAEGgleITVTGELESKPYRDHTERMLRAFGVEVEVEGyRRFTVPGGQ 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 78 V---QDIPMPyGKINSlrASYYFYGSLLGrfGQAVVgLPGgcdLGPRPIDLH---LKAFEAMGVEVSYEGENmnLSTNGQ 151
Cdd:COG0128 228 RyrpGDYTVP-GDISS--AAFFLAAAAIT--GSEVT-VEG---VGLNSTQGDtgiLDILKEMGADIEIENDG--ITVRGS 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 152 KIHGAHIYMDTVSVGA-TIntMVAATKAQGKTVIENAA--REPE---IIDVATLLNNMGAHIRgAGTDIITIQGVQKLHG 225
Cdd:COG0128 297 PLKGIDIDLSDIPDEApTL--AVLAAFAEGTTRIRGAAelRVKEsdrIAAMATELRKLGADVE-ETEDGLIIEGGPKLKG 373
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 489079357 226 TrhqvipdRIEagTY----IALAAAI-----GKGVKITNV 256
Cdd:COG0128 374 A-------EVD--SYgdhrIAMAFAVaglraEGPVTIDDA 404
|
|
| AroA |
COG0128 |
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ... |
28-297 |
1.67e-07 |
|
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439898 Cd Length: 421 Bit Score: 53.17 E-value: 1.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 28 LIPAIILADDIVILDGVPAIS--DVDSLIEIMELMGATVNYHGDT---LEIDPRGVQ--DIPMPyGKINS-------LRA 93
Cdd:COG0128 100 LTGLLALQPGEVVLTGDESLRkrPMGRLLDPLRQLGARIESRGGGylpLTIRGGPLKggEYEIP-GSASSqfksallLAG 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 94 SYYFYGSLLgrfgqAVVGlpggcDLGPRP-IDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIymdTV----SVGAT 168
Cdd:COG0128 179 PLAEGGLEI-----TVTG-----ELESKPyRDHTERMLRAFGVEVEVEGYRRFTVPGGQRYRPGDY---TVpgdiSSAAF 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 169 IntMVAATKAQGKTVIENAAREP-----EIIDVatlLNNMGAHIRgAGTDIITIQGvQKLHGTR---HQvIPDriEAGTy 240
Cdd:COG0128 246 F--LAAAAITGSEVTVEGVGLNStqgdtGILDI---LKEMGADIE-IENDGITVRG-SPLKGIDidlSD-IPD--EAPT- 314
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489079357 241 IALAAAIGKGV-KITNVlyEHL---ES-----FIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKT 297
Cdd:COG0128 315 LAVLAAFAEGTtRIRGA--AELrvkESdriaaMATELRKLGADVEETEDGLIIEGGPKLKGAEVDS 378
|
|
| EPT_RTPC-like |
cd01553 |
This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate ... |
232-410 |
1.36e-06 |
|
This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats with a 4th slightly different domain inserted between the 2nd and 3rd repeat. They evidently share the same active site location, although the catalytic residues differ.
Pssm-ID: 238794 Cd Length: 211 Bit Score: 48.81 E-value: 1.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 232 PDRIEAGTYIALAAAIGKGVKITNV--------LYEHLESFIAKLEEMgVRMTVEE----DAIFVEKQESLKAITIKTSP 299
Cdd:cd01553 8 GGGQILRSFLVLAAISGGPITVTGIrpdrakpgLLRQHLTFLKALEKI-CGATVEGgelgSDRISFRPGTVRGGDVRFAI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 300 YP-GFATDLQQPLTPLLLKADGRGTIIDTIY----------EKRINHVPELMRMGA------------DISVIGGQIVYQ 356
Cdd:cd01553 87 GSaGSCTDVLQTILPLLLFAKGPTRLTVTGGtdnpsappadFIRFVLEPELAKIGAhqeetllrhgfyPAGGGVVATEVS 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 489079357 357 GPSRLTGAQVKATDLragaalvtaGLIAEGKTEITNIEFILRGYASIIAKLTAL 410
Cdd:cd01553 167 PVEKLNTAQLRQLVL---------PMLLASGAVEFTVAHPSCHLLTNFAVLEAL 211
|
|
| PRK14806 |
PRK14806 |
bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; ... |
112-303 |
5.20e-03 |
|
bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 237820 [Multi-domain] Cd Length: 735 Bit Score: 39.21 E-value: 5.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 112 LPGGCDLGPRPIDLHLKAFEAMG--VEVSYEGENMNLSTNGQKIHGAHIYMDTVSVGATINTMVAATKAQGKTVIenaaR 189
Cdd:PRK14806 414 LTGDASLSKRPMERVAKPLREMGavIETGEEGRPPLSIRGGQRLKGIHYDLPMASAQVKSCLLLAGLYAEGETSV----T 489
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079357 190 EPEIIDVAT--LLNNMGAHIRGAGtDIITIQGVQKLHGTrHQVIPDRIEAGTYIALAAAIGKGVKITnvlYEHL------ 261
Cdd:PRK14806 490 EPAPTRDHTerMLRGFGYPVKVEG-NTISVEGGGKLTAT-DIEVPADISSAAFFLVAASIAEGSELT---LEHVginptr 564
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 489079357 262 ESFIAKLEEMGVRMTVEEDAIFveKQESLKAITIKTSPYPGF 303
Cdd:PRK14806 565 TGVIDILKLMGADITLENEREV--GGEPVADIRVRGARLKGI 604
|
|
| |
