|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15083 |
PRK15083 |
PTS system mannitol-specific transporter subunit IICBA; Provisional |
1-634 |
0e+00 |
|
PTS system mannitol-specific transporter subunit IICBA; Provisional
Pssm-ID: 237905 [Multi-domain] Cd Length: 639 Bit Score: 1301.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 1 MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVV 80
Cdd:PRK15083 2 MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 81 GAITTMGVIVGADMPMFLGSMIAGPLGGYCIKKFDNWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKI 160
Cdd:PRK15083 82 GAITTMGVIVGADMPMFLGAMIAGPLGGWAIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 161 LAAGVNFMVAHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSAK 240
Cdd:PRK15083 162 LAAGVNFMVVHDLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSAK 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 241 QSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTILNGGLVSPASPGSILAVLAMTPKGAYFANIAAII 320
Cdd:PRK15083 242 QSAGGAAIIHFFGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTLLNGGLVSPASPGSILAVLAMTPKGAYFANIASVA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 321 AAMAVSFVVSAVLLKTSKVKEEDDIEAATRRMHDMKAESKGASPLAAGNVTNDLSHVRKIIVACDAGMGSSAMGAGVLRK 400
Cdd:PRK15083 322 AAMAVSFVVSAILLKTSKVKEEDDLEAATRRMQDMKAESKGASPLAAGDVTNDLSHVRKIIVACDAGMGSSAMGAGVLRK 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 401 KVQDAGLSNISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGLYTSLTERLVAAQRHIDNEVKVTD 480
Cdd:PRK15083 402 KVQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGLYTSLTERLVAAQRHTENEEKVKD 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 481 SLKDSFDDTNNNLFQLGADNIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAK 560
Cdd:PRK15083 482 SLKDSFEDSSANLFKLGAENIFLGLKAATKEEAIRFAGEQLVKGGYVEPEYVDAMLDREKLTSTYLGESIAVPHGTVEAK 561
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489011859 561 DRVLKTGVVFCQYPEGVRFGEEEDEVARLVIGIAARNNEHIQVITSLTNALDDETVIERLAKTTSVDEVLALLN 634
Cdd:PRK15083 562 DRVLKTGVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTTSVDEVLELLA 635
|
|
| MtlA |
COG2213 |
Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and ... |
2-470 |
0e+00 |
|
Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism];
Pssm-ID: 441815 [Multi-domain] Cd Length: 479 Bit Score: 830.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 2 SSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVG 81
Cdd:COG2213 6 KGSARAKVQKFGRFLSGMVMPNIGAFIAWGLITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKMVYGVRGGVVG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 82 AITTMGVIVGADMPMFLGSMIAGPLGGYCIKKFDNWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKIL 161
Cdd:COG2213 86 AIATMGVIVGADIPMFLGAMIMGPLGGWVIKKFDKLIEGKIKAGFEMLVNNFSAGILGMLLAILAFFAIGPVVEGLSNAL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 162 AAGVNFMVAHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSAKQ 241
Cdd:COG2213 166 AAGVEWLVNAGLLPLASIFIEPAKVLFLNNAINHGILTPLGIQQAAETGKSILFLLEANPGPGLGILLAYMFFGKGSAKQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 242 SAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTILNGGLVSPASPGSILAVLAMTPKGAYFANIAAIIA 321
Cdd:COG2213 246 SAPGAIIIHFFGGIHEIYFPYVLMKPLLILAVIAGGMTGVFTFVLFGAGLVAPASPGSIFAVLAMTPKGSYLGVILGVLV 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 322 AMAVSFVVSAVLLKTSKVKE-EDDIEAATRRMHDMKAESKGAS---PLAAGNVTNDLSHVRKIIVACDAGMGSSAMGAGV 397
Cdd:COG2213 326 AAAVSFLVASIILKRSKSKEdEDDLEAATAKMEAMKGKSSSVAsalTAAAAVGAADASNVKKIVFACDAGMGSSAMGASV 405
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489011859 398 LRKKVQDAGLsNISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGLYTSLTERLVAAQR 470
Cdd:COG2213 406 LRKKVKKAGL-DIEVTNTAINNLPDDADLVITHKDLTERAKQKAPNAQHISVDNFLNSPKYDELVEKLKKQND 477
|
|
| mtlA |
TIGR00851 |
PTS system, mannitol-specific IIC component; Bacterial PTS transporters transport and ... |
8-345 |
0e+00 |
|
PTS system, mannitol-specific IIC component; Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities.The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This family is specific for the IIC domain of the mannitol PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]
Pssm-ID: 129930 Cd Length: 338 Bit Score: 534.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 8 KVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMG 87
Cdd:TIGR00851 1 KVQRFGSFLSGMIMPNIGAFIAWGIITALFIPTGWFPNETLAKLVGPMITYLLPLLIAYTGGKLIYDLRGGVVGATATMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 88 VIVGADMPMFLGSMIAGPLGGYCIKKFDNWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKILAAGVNF 167
Cdd:TIGR00851 81 VIVGSDIPMFLGAMIMGPLGGWLIKKTDEFVQGKVKQGFEMLVNNFSAGIIGFILTILAFEGIGPIVKAISKILAAGVEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 168 MVAHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSAKQSAGGAA 247
Cdd:TIGR00851 161 IVHAHLLPLASIFVEPAKILFLNNAINHGIFSPLGIEQAAHTGKSILFLIEANPGPGLGVLLAYMFFGKGSAKQTAPGAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 248 IIHFLGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTILNGGLVSPASPGSILAVLAMTPKGAYFANIAAIIAAMAVSF 327
Cdd:TIGR00851 241 IIHFFGGIHEIYFPYVLMRPLLILAVILGGMTGVLTYTILDAGLVAPASPGSIIALLAMTPKGEYLGVLAGVLVAAAVSF 320
|
330
....*....|....*...
gi 489011859 328 VVSAVLLKTSKVKEEDDI 345
Cdd:TIGR00851 321 VVSAIILKSSKDPEEDLI 338
|
|
| PTS_IIA_fru |
cd00211 |
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: ... |
498-633 |
4.88e-44 |
|
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.
Pssm-ID: 238129 [Multi-domain] Cd Length: 136 Bit Score: 153.87 E-value: 4.88e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 498 ADNIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAkdrVLKTGVVFCQYPEGV 577
Cdd:cd00211 3 KENIRLNLKAKSKEEAIEELAQLLVAAGYVEEEYIEALLEREKEGSTGIGNGIAIPHAKSEA---VKKPGIAVLRLKEPV 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 489011859 578 RFGEEEDEVARLVIGIAARN-NEHIQVITSLTNALDDETVIERLAKTTSVDEVLALL 633
Cdd:cd00211 80 DFGSLDGQPVHLIFLLAAPDsNEHLKALSQLARLLSDEEFVEQLLNAQSKEEILALL 136
|
|
| PTS_EIIA_2 |
pfam00359 |
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; |
496-634 |
7.24e-37 |
|
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;
Pssm-ID: 459780 [Multi-domain] Cd Length: 139 Bit Score: 134.26 E-value: 7.24e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 496 LGADNIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAkdrVLKTGVVFCQYPE 575
Cdd:pfam00359 2 LDKELIFLNLEAKSKEEAIEFLADKLVEAGYVEPAYLEAILEREKEGSTGIGNGIAIPHARSEA---VKKPGIAVLTLKE 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489011859 576 GVRFGEEEDEVARLVIGIAARNNE--HIQVITSLTNALDDETVIERLAKTTSVDEVLALLN 634
Cdd:pfam00359 79 PVDFGSEDGKPVKLIFLLAAPDNEasHLKILSQLARLLQDEEFVEKLLKAKDPEEILEILK 139
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15083 |
PRK15083 |
PTS system mannitol-specific transporter subunit IICBA; Provisional |
1-634 |
0e+00 |
|
PTS system mannitol-specific transporter subunit IICBA; Provisional
Pssm-ID: 237905 [Multi-domain] Cd Length: 639 Bit Score: 1301.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 1 MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVV 80
Cdd:PRK15083 2 MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 81 GAITTMGVIVGADMPMFLGSMIAGPLGGYCIKKFDNWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKI 160
Cdd:PRK15083 82 GAITTMGVIVGADMPMFLGAMIAGPLGGWAIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 161 LAAGVNFMVAHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSAK 240
Cdd:PRK15083 162 LAAGVNFMVVHDLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSAK 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 241 QSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTILNGGLVSPASPGSILAVLAMTPKGAYFANIAAII 320
Cdd:PRK15083 242 QSAGGAAIIHFFGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTLLNGGLVSPASPGSILAVLAMTPKGAYFANIASVA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 321 AAMAVSFVVSAVLLKTSKVKEEDDIEAATRRMHDMKAESKGASPLAAGNVTNDLSHVRKIIVACDAGMGSSAMGAGVLRK 400
Cdd:PRK15083 322 AAMAVSFVVSAILLKTSKVKEEDDLEAATRRMQDMKAESKGASPLAAGDVTNDLSHVRKIIVACDAGMGSSAMGAGVLRK 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 401 KVQDAGLSNISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGLYTSLTERLVAAQRHIDNEVKVTD 480
Cdd:PRK15083 402 KVQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGLYTSLTERLVAAQRHTENEEKVKD 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 481 SLKDSFDDTNNNLFQLGADNIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAK 560
Cdd:PRK15083 482 SLKDSFEDSSANLFKLGAENIFLGLKAATKEEAIRFAGEQLVKGGYVEPEYVDAMLDREKLTSTYLGESIAVPHGTVEAK 561
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489011859 561 DRVLKTGVVFCQYPEGVRFGEEEDEVARLVIGIAARNNEHIQVITSLTNALDDETVIERLAKTTSVDEVLALLN 634
Cdd:PRK15083 562 DRVLKTGVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTTSVDEVLELLA 635
|
|
| MtlA |
COG2213 |
Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and ... |
2-470 |
0e+00 |
|
Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism];
Pssm-ID: 441815 [Multi-domain] Cd Length: 479 Bit Score: 830.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 2 SSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVG 81
Cdd:COG2213 6 KGSARAKVQKFGRFLSGMVMPNIGAFIAWGLITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKMVYGVRGGVVG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 82 AITTMGVIVGADMPMFLGSMIAGPLGGYCIKKFDNWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKIL 161
Cdd:COG2213 86 AIATMGVIVGADIPMFLGAMIMGPLGGWVIKKFDKLIEGKIKAGFEMLVNNFSAGILGMLLAILAFFAIGPVVEGLSNAL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 162 AAGVNFMVAHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSAKQ 241
Cdd:COG2213 166 AAGVEWLVNAGLLPLASIFIEPAKVLFLNNAINHGILTPLGIQQAAETGKSILFLLEANPGPGLGILLAYMFFGKGSAKQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 242 SAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTILNGGLVSPASPGSILAVLAMTPKGAYFANIAAIIA 321
Cdd:COG2213 246 SAPGAIIIHFFGGIHEIYFPYVLMKPLLILAVIAGGMTGVFTFVLFGAGLVAPASPGSIFAVLAMTPKGSYLGVILGVLV 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 322 AMAVSFVVSAVLLKTSKVKE-EDDIEAATRRMHDMKAESKGAS---PLAAGNVTNDLSHVRKIIVACDAGMGSSAMGAGV 397
Cdd:COG2213 326 AAAVSFLVASIILKRSKSKEdEDDLEAATAKMEAMKGKSSSVAsalTAAAAVGAADASNVKKIVFACDAGMGSSAMGASV 405
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489011859 398 LRKKVQDAGLsNISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGLYTSLTERLVAAQR 470
Cdd:COG2213 406 LRKKVKKAGL-DIEVTNTAINNLPDDADLVITHKDLTERAKQKAPNAQHISVDNFLNSPKYDELVEKLKKQND 477
|
|
| mtlA |
TIGR00851 |
PTS system, mannitol-specific IIC component; Bacterial PTS transporters transport and ... |
8-345 |
0e+00 |
|
PTS system, mannitol-specific IIC component; Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities.The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This family is specific for the IIC domain of the mannitol PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]
Pssm-ID: 129930 Cd Length: 338 Bit Score: 534.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 8 KVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMG 87
Cdd:TIGR00851 1 KVQRFGSFLSGMIMPNIGAFIAWGIITALFIPTGWFPNETLAKLVGPMITYLLPLLIAYTGGKLIYDLRGGVVGATATMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 88 VIVGADMPMFLGSMIAGPLGGYCIKKFDNWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKILAAGVNF 167
Cdd:TIGR00851 81 VIVGSDIPMFLGAMIMGPLGGWLIKKTDEFVQGKVKQGFEMLVNNFSAGIIGFILTILAFEGIGPIVKAISKILAAGVEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 168 MVAHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSAKQSAGGAA 247
Cdd:TIGR00851 161 IVHAHLLPLASIFVEPAKILFLNNAINHGIFSPLGIEQAAHTGKSILFLIEANPGPGLGVLLAYMFFGKGSAKQTAPGAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 248 IIHFLGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTILNGGLVSPASPGSILAVLAMTPKGAYFANIAAIIAAMAVSF 327
Cdd:TIGR00851 241 IIHFFGGIHEIYFPYVLMRPLLILAVILGGMTGVLTYTILDAGLVAPASPGSIIALLAMTPKGEYLGVLAGVLVAAAVSF 320
|
330
....*....|....*...
gi 489011859 328 VVSAVLLKTSKVKEEDDI 345
Cdd:TIGR00851 321 VVSAIILKSSKDPEEDLI 338
|
|
| MtlA2 |
COG4668 |
Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and ... |
494-635 |
2.05e-67 |
|
Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism];
Pssm-ID: 443705 [Multi-domain] Cd Length: 143 Bit Score: 216.56 E-value: 2.05e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 494 FQLGADNIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAKDRVLKTGVVFCQY 573
Cdd:COG4668 2 LILTKENIRLNASAANKEEAIRLAGQLLVEAGYVEPEYIDAMLEREAQVSTYLGNGIAIPHGTNEAKDLVLKTGISVLQF 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489011859 574 PEGVRFGeeEDEVARLVIGIAARNNEHIQVITSLTNALDDETVIERLAKTTSVDEVLALLNK 635
Cdd:COG4668 82 PDGVDWG--DGNTVYLVIGIAAKSDEHLEILRQLARVLSDEENVEKLAKATDAEEILALLTG 141
|
|
| PTS_IIA_fru |
cd00211 |
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: ... |
498-633 |
4.88e-44 |
|
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.
Pssm-ID: 238129 [Multi-domain] Cd Length: 136 Bit Score: 153.87 E-value: 4.88e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 498 ADNIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAkdrVLKTGVVFCQYPEGV 577
Cdd:cd00211 3 KENIRLNLKAKSKEEAIEELAQLLVAAGYVEEEYIEALLEREKEGSTGIGNGIAIPHAKSEA---VKKPGIAVLRLKEPV 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 489011859 578 RFGEEEDEVARLVIGIAARN-NEHIQVITSLTNALDDETVIERLAKTTSVDEVLALL 633
Cdd:cd00211 80 DFGSLDGQPVHLIFLLAAPDsNEHLKALSQLARLLSDEEFVEQLLNAQSKEEILALL 136
|
|
| PRK11109 |
PRK11109 |
fused PTS fructose transporter subunit IIA/HPr protein; |
493-634 |
5.14e-41 |
|
fused PTS fructose transporter subunit IIA/HPr protein;
Pssm-ID: 236849 [Multi-domain] Cd Length: 375 Bit Score: 153.18 E-value: 5.14e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 493 LFQLGADNIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAKDRVLKTGVVFCQ 572
Cdd:PRK11109 1 MFQLSVQDIHLGQQAGNKEEAIRQVAAALTQAGNVAEGYVDGMLAREQQTSTFLGNGIAIPHGTTDTRDLVLKTGVQVFQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489011859 573 YPEGVRFGeeEDEVARLVIGIAARNNEHIQVITSLTNALDDETVIERLAKTTSVDEVLALLN 634
Cdd:PRK11109 81 FPQGVTWG--DGQTAYVAIGIAAKSDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLM 140
|
|
| PTS_IIB_mannitol |
cd05567 |
PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate: ... |
378-465 |
4.17e-37 |
|
PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain. The IIA, IIB, and IIC domains are expressed from the mtlA gene as a single protein, also known as the mannitol PTS permease, the mtl transporter, or MtlA. MtlA is only functional as a dimer with the dimer contacts occuring between the IIC domains. MtlA takes up exogenous mannitol releasing the phosphate ester into the cytoplasm in preparation for oxidation to fructose-6-phosphate by the NAD-dependent mannitol-P dehydrogenase (MtlD). The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include mannitol, chitobiose/lichenan, ascorbate, lactose, galactitol, fructose, and a sensory system with similarity to the bacterial bgl system.
Pssm-ID: 99909 [Multi-domain] Cd Length: 87 Bit Score: 133.08 E-value: 4.17e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 378 RKIIVACDAGMGSSAMGAGVLRKKVQDAGLsNISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGL 457
Cdd:cd05567 1 KKIVFACDAGMGSSAMGASVLRKKLKKAGL-EIPVTNSAIDELPSDADLVVTHASLTDRAKKKAPQAQHLSVDNFLNTPE 79
|
....*...
gi 489011859 458 YTSLTERL 465
Cdd:cd05567 80 YDELIERL 87
|
|
| PTS_EIIA_2 |
pfam00359 |
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; |
496-634 |
7.24e-37 |
|
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;
Pssm-ID: 459780 [Multi-domain] Cd Length: 139 Bit Score: 134.26 E-value: 7.24e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 496 LGADNIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAkdrVLKTGVVFCQYPE 575
Cdd:pfam00359 2 LDKELIFLNLEAKSKEEAIEFLADKLVEAGYVEPAYLEAILEREKEGSTGIGNGIAIPHARSEA---VKKPGIAVLTLKE 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489011859 576 GVRFGEEEDEVARLVIGIAARNNE--HIQVITSLTNALDDETVIERLAKTTSVDEVLALLN 634
Cdd:pfam00359 79 PVDFGSEDGKPVKLIFLLAAPDNEasHLKILSQLARLLQDEEFVEKLLKAKDPEEILEILK 139
|
|
| PtsN |
COG1762 |
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ... |
496-635 |
1.35e-35 |
|
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 441368 [Multi-domain] Cd Length: 150 Bit Score: 131.13 E-value: 1.35e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 496 LGADNIFLGRKAATKEEAIRFAGEQLVKGGYV--EPEYVQAMLDREKLTSTYLGESIAVPHGTIEAkdrVLKTGVVFCQY 573
Cdd:COG1762 7 LTPELILLDLEASSKEEAIEELAELLAEKGYVldKEEYLEALLEREELGSTGIGPGIAIPHARPEG---VKKPGIAVARL 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489011859 574 PEGVRFGEEEDEVARLVIGIAA---RNNEHIQVITSLTNALDDETVIERLAKTTSVDEVLALLNK 635
Cdd:COG1762 84 KEPVDFGAMDGEPVDLVFLLAApedDSEEHLKLLAELARLLSDEEFREKLLNAKSPEEILELLKE 148
|
|
| PRK13779 |
PRK13779 |
bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional |
493-633 |
2.37e-34 |
|
bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional
Pssm-ID: 237502 [Multi-domain] Cd Length: 503 Bit Score: 136.93 E-value: 2.37e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 493 LFQLGADNIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAKDRVLKTGVVFCQ 572
Cdd:PRK13779 1 MLNLSESNIHLNAQAINKQQAIEMAAAALEQAGNVENGYLQGMLARELQTSTFLGNGIAIPHGTLDTRHMVKNTGVQIFQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489011859 573 YPEGVRFGeeEDEVARLVIGIAARNNEHIQVITSLTNALDDETVIERLAKTTSVDEVLALL 633
Cdd:PRK13779 81 FPQGIEWG--EGNIAYVVIGIAARSDEHLSLLRQLTHVLSDEDTAAKLATLTDVKEFRAIL 139
|
|
| PTS_EIIC |
pfam02378 |
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ... |
17-276 |
6.72e-23 |
|
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.
Pssm-ID: 367061 Cd Length: 315 Bit Score: 99.73 E-value: 6.72e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 17 SNMVMPNIGAFIAWGIITAL------------FIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGK-------------- 70
Cdd:pfam02378 1 GDGFMPPIPLLIAGGILLGLgnlpndttglpaGGFTGDSPLAEILKQAGSAAFGILPILFAIGIAYglaggdgvagaagl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 71 ---LVGGERGGVVGAITTMGVIVGADMP-------MFLGSMIAGPLGGYCIKKFDNWVDGKIKSGFEMLVnnfSAGIIGM 140
Cdd:pfam02378 81 iglLSFNLAAAISVALTAAGLSGGGNILgiglgatGVFGAIIPGLLAAYLYNRFEKNITIKLPDSLPFFV---GKRFVPI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 141 ILAILAFLGIGPAVEVLSKILAAGVNfmvahdmLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSI------- 213
Cdd:pfam02378 158 ITGFVTLLVIGPVLGLIWPAIQGGLN-------ALGLLLIIAGGILGGLIFGFLERLLWPFGLHGAFIAIFWFlpiggsn 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 214 -------------------FFLIEANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIY---FPYVLMNPRLIL 271
Cdd:pfam02378 231 pianqqaygagaahiltggFDVMFGGPGATLALYAAAFLFKKSKVKKLLGSAALTPFLFGITEPLefgFPFVLNPPFFIP 310
|
....*
gi 489011859 272 AVILG 276
Cdd:pfam02378 311 AILAG 315
|
|
| fruA |
TIGR00848 |
PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family ... |
496-620 |
2.52e-17 |
|
PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]
Pssm-ID: 273298 [Multi-domain] Cd Length: 129 Bit Score: 78.47 E-value: 2.52e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 496 LGADNIFLGRKAATKEEAIRFAGEQLVKGGYVE--PEYVQAMLDREKLTSTYLGESIAVPHGTIEAkdrVLKTGVVFCQY 573
Cdd:TIGR00848 2 LNKDLIFLDQQFTSKEDVIKFLANKLLENGYISdtEEFLEDLLKREEEGTTGIGDGVAIPHAKSAA---VKQPFVAIARL 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 489011859 574 PEGVRFGEEEDEVARLVIGIAA----RNNEHIQVITSLTNALDDETVIERL 620
Cdd:TIGR00848 79 VKGVDWQSLDGKPVKLIFLIAVpkdeAGNTHLKALSQLARLLLNDEFRAKL 129
|
|
| PRK09765 |
PRK09765 |
PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional |
499-634 |
3.29e-15 |
|
PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional
Pssm-ID: 182066 [Multi-domain] Cd Length: 631 Bit Score: 79.01 E-value: 3.29e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 499 DNIFLGRKAATKEEAIRFAGEQLVKGG--YVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAkdrVLKTGVVFCQYPEG 576
Cdd:PRK09765 10 DLLCLNARFTSREEAIHALAQRLAALGkiSSTEQFLEEVYRRESLGPTALGEGLAVPHGKTAA---VKEAAFAVATLSEP 86
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489011859 577 VRF-GEEEDEVARLVIGIAARNNE----HIQVITSLTNALDDETVIERLAKTTSVDEVLALLN 634
Cdd:PRK09765 87 LQWeGVDGPEAVDLIFLLAIPPNEagttHMQLLTALTTRLADDEIRARIQSATTPDELLSALD 149
|
|
| PRK10372 |
PRK10372 |
PTS ascorbate transporter subunit IIA; |
500-635 |
1.32e-13 |
|
PTS ascorbate transporter subunit IIA;
Pssm-ID: 182417 [Multi-domain] Cd Length: 154 Bit Score: 68.85 E-value: 1.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 500 NIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTY--LGESIAVPHGTIEakDRVLKTGVVFCQYPEGV 577
Cdd:PRK10372 12 SIRLQAEAETWQEAVKIGVDLLVAADVVEPRYYQAILDGVEQFGPYfvIAPGLAMPHGRPE--EGVKKTGFALVTLKKPL 89
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 578 RFGEEEDEVARLVIGIAARN-NEHIQV-ITSLTNALDDETVIERLAKTTSVDEVLALLNK 635
Cdd:PRK10372 90 EFNHEDNDPVDILITMAAVDaNTHQEVgIMQIVNLFEDEANFDRLRACRTEQEVLDLIDR 149
|
|
| cmtB |
PRK09854 |
PTS mannitol transporter subunit IIA; |
511-635 |
3.87e-10 |
|
PTS mannitol transporter subunit IIA;
Pssm-ID: 182114 [Multi-domain] Cd Length: 147 Bit Score: 58.46 E-value: 3.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 511 EEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTSTY--LGESIAVPHGTIEAKdrVLKTGVVFCQYPEGVRFGEEEDEVaR 588
Cdd:PRK09854 22 QEAIDFSMVSLLDKNYISENYIQAIKDSTINNGPYyiLAPGVAMPHARPECG--ALKTGMSLTLLEQGVYFPGNDEPI-K 98
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 489011859 589 LVIGI-AARNNEHIQVITSLTNALDDETVIERLAKTTSVDEVLALLNK 635
Cdd:PRK09854 99 LLIGLsAADADSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISR 146
|
|
| PTS_IIB |
pfam02302 |
PTS system, Lactose/Cellobiose specific IIB subunit; The bacterial phosphoenolpyruvate: sugar ... |
379-454 |
4.10e-08 |
|
PTS system, Lactose/Cellobiose specific IIB subunit; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The lactose/cellobiose-specific family are one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes. The fold of IIB cellobiose shows similar structure to mammalian tyrosine phosphatases. This family also contains the fructose specific IIB subunit.
Pssm-ID: 396744 Cd Length: 92 Bit Score: 51.18 E-value: 4.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 379 KIIVACDAGMGSSAMGAGVLRKKVQDAGLSNISVTNSA----INNLPPDVDLVITHRDLTERAMRQVP--QAQHISLTNF 452
Cdd:pfam02302 1 KILTACGAGMATSLMAAEALEKAAKELGIVEAQGAAGVneltAEDIADDADVVILAPDVAVEDLARFAgkPVYVIPVKDA 80
|
..
gi 489011859 453 LD 454
Cdd:pfam02302 81 LG 82
|
|
| nitro_reg_IIA |
TIGR01419 |
PTS IIA-like nitrogen-regulatory protein PtsN; This model describes a full-length protein of ... |
520-633 |
4.50e-08 |
|
PTS IIA-like nitrogen-regulatory protein PtsN; This model describes a full-length protein of about 160 residues closely related to the fructose-specific phosphotransferase (PTS) system IIA component. It is a regulatory protein found only in species with a phosphoenolpyruvate-protein phosphotransferase (enzyme I of PTS systems) and an HPr-like phosphocarrier protein, but not all species have a IIC-like permease. Members of this family are found in Proteobacteria, Chlamydia, and the spirochete Treponema pallidum. [Signal transduction, PTS]
Pssm-ID: 162350 [Multi-domain] Cd Length: 145 Bit Score: 52.41 E-value: 4.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 520 QLVKGGYVEPEYV--QAMLDREKLTSTYLGESIAVPHGTIEAKDRVLKtgvVFCQYPEGVRFGEEEDEVARLVIGI---A 594
Cdd:TIGR01419 29 LLAARELSLPEQDvfECLLAREKLGSTGVGNGIAIPHGRLSGLKQPVG---VFIRLDAPVDFDALDGKPVDLLFALlvpE 105
|
90 100 110
....*....|....*....|....*....|....*....
gi 489011859 595 ARNNEHIQVITSLTNALDDETVIERLAkTTSVDEVLALL 633
Cdd:TIGR01419 106 NATAEHLEALSRIARKLSDKTICRRLR-AASAEEIYQIL 143
|
|
| PTS_IIB |
cd00133 |
PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the ... |
379-436 |
1.87e-07 |
|
PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include chitobiose/lichenan, ascorbate, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system. The PTS is found only in bacteria, where it catalyzes the transport and phosphorylation of numerous monosaccharides, disaccharides, polyols, amino sugars, and other sugar derivatives. The four proteins (domains) forming the PTS phosphorylation cascade (EI, HPr, EIIA, and EIIB), can phosphorylate or interact with numerous non-PTS proteins thereby regulating their activity.
Pssm-ID: 99904 Cd Length: 84 Bit Score: 48.79 E-value: 1.87e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 379 KIIVACDAGMGSSAMGAGVLRKKVQDAGLsNISVTNSAINNL--PPDVDLVITHRDLTER 436
Cdd:cd00133 1 KILVVCGSGIGSSSMLAEKLEKAAKELGI-EVKVEAQGLSEVidLADADLIISTVPLAAR 59
|
|
| PRK09913 |
PRK09913 |
PTS fructose transporter subunit IIA; |
496-635 |
3.01e-07 |
|
PTS fructose transporter subunit IIA;
Pssm-ID: 182141 [Multi-domain] Cd Length: 148 Bit Score: 50.27 E-value: 3.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 496 LGADNIFLGRKAATKEEAIRFAGEQLVKGGYVE--PEYVQAMLDREKLTSTYLGESIAVPHGTieaKDRVLKTGVVFCQY 573
Cdd:PRK09913 4 LTASCIDLNIQGNGAYSILKQLATIALQNGFITdsHQFLQTLLLREKMHSTGFGSGVAVPHGK---SACVKQPFVLFARK 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489011859 574 PEGVRFGEEEDEVARLVIGI---AARNNEHIQVITSLTNALDDETVIERLaKTTSVDEVLALLNK 635
Cdd:PRK09913 81 AQAIDWQASDGEDVNCWICLgvpQSGEEDQVKIIGTLCRKIIHQDFIHQL-KQGDTDQVLALLNQ 144
|
|
| PRK10896 |
PRK10896 |
PTS IIA-like nitrogen regulatory protein PtsN; |
533-633 |
1.42e-04 |
|
PTS IIA-like nitrogen regulatory protein PtsN;
Pssm-ID: 182818 [Multi-domain] Cd Length: 154 Bit Score: 42.43 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 533 QAMLDREKLTSTYLGESIAVPHGTIEakDRVLKTGVVFCQYPEGVRFGEEEDEVARLVIGI---AARNNEHIQVITSLTN 609
Cdd:PRK10896 51 EAILTREKMGSTGIGNGIAIPHGKLE--EDTLRAVGVFVQLEQPIAFDAIDNQPVDLLFALlvpADQCKTHLHTLSLVAK 128
|
90 100
....*....|....*....|....
gi 489011859 610 ALDDETVIERLAKTTSVDEVLALL 633
Cdd:PRK10896 129 RLADKTICRRLRAAQSDEELYQII 152
|
|
| SgaB |
COG3414 |
Phosphotransferase system, galactitol-specific IIB component [Carbohydrate transport and ... |
379-454 |
2.92e-04 |
|
Phosphotransferase system, galactitol-specific IIB component [Carbohydrate transport and metabolism];
Pssm-ID: 442640 Cd Length: 94 Bit Score: 40.16 E-value: 2.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 379 KIIVACDAGMGSSAMgagvLRKKVQDA----GLsNISVTNSAINNLPP---DVDLVITHRDLTERAmrQVPQAQHISLTN 451
Cdd:COG3414 3 KILVVCGSGLGTSTM----LKMKIEKVlkelGI-DAEVEHCDVSSAKSkadDADLIVTTTDLAEEL--GIPVINVIPLLN 75
|
...
gi 489011859 452 FLD 454
Cdd:COG3414 76 GID 78
|
|
| PTS_IIB_ascorbate |
cd05563 |
PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific ... |
379-454 |
4.04e-03 |
|
PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.
Pssm-ID: 99905 Cd Length: 86 Bit Score: 36.74 E-value: 4.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011859 379 KIIVACDAGMGSSAMgagvLRKKVQDA----GLsNISVTNSAINNLPPD-VDLVITHRDLTERAmrQVPQAQHISLTNFL 453
Cdd:cd05563 1 KILAVCGSGLGSSLM----LKMNVEKVlkelGI-EAEVEHTDLGSAKASsADIIVTSKDLASLL--ADGGAKVIGLKNIM 73
|
.
gi 489011859 454 D 454
Cdd:cd05563 74 D 74
|
|
| |
