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Conserved domains on  [gi|489011585|ref|WP_002922127|]
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MULTISPECIES: glycine--tRNA ligase subunit beta [Klebsiella]

Protein Classification

glycine--tRNA ligase subunit beta( domain architecture ID 11433536)

glycine--tRNA ligase subunit beta is part of a class-II aminoacyl-tRNA synthetase that catalyzes the conversion from ATP, glycine, and tRNA(Gly) to AMP, diphosphate, and glycyl-tRNA(Gly)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GlyS COG0751
Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; ...
4-689 0e+00

Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; Glycyl-tRNA synthetase, beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


:

Pssm-ID: 440514 [Multi-domain]  Cd Length: 690  Bit Score: 1145.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585   4 NTFLVEIGTEELPPKALRSLAESFAANVTAELDNAGLAHGKVEWFAAPRRLALKVANLAAAQADREVEKRGPAIAQAFDA 83
Cdd:COG0751    3 KDLLLEIGTEELPAKFLPKLLEQLAELLAAGLKEARLSFGEVEVYATPRRLAVLVEGLAEKQPDREEEVKGPPVKAAFDA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  84 EGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMIASSLAKLPIPKLMRWGASDVHFVRPVHT 163
Cdd:COG0751   83 DGNPTKAALGFARSQGVDVDDLERRETDKGEYLFARKTIKGRPTAELLPEILPEAIAKLPFPKSMRWGDGDVRFVRPVRW 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 164 VTLLLGDKVIPATILGIPSDRVIRGHRFMGEPEFTIDHADQYPQILlERGKVIADYEQRKAKIKADAQEAARKIGGQADL 243
Cdd:COG0751  163 LVALLGDEVVPFEILGLKSGRTTRGHRFLGPGPIEIASADDYEETL-REGYVIADFEERRELIREQLEAAAAELGGTADI 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 244 SESLLEEVTSLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPQQIISGNEKVV 323
Cdd:COG0751  242 DEDLLDEVTNLVEWPTALLGSFDEEFLELPQEVLITTMKEHQRYFPVLDADGKLLPYFITVSNGESKDPENVIAGNERVL 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 324 RPRLADAEFFFNTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWIAEQIGAD--VNHATRAGLLSKCDLMTNM 401
Cdd:COG0751  322 RARLADAKFFYEEDLKKPLEDRVEKLKKVVFQEKLGTLADKVERIEALAAAIAEQLGLDeeAALAERAALLAKADLVTQM 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 402 VFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDALPSNPVACAVAIADKMDTLAGIFGIGQHPKGDKDPFALR 481
Cdd:COG0751  402 VGEFPELQGIMGRYYALHDGEPEEVALAIEEHYLPRFAGDALPSTLVGAIVALADKLDTLVGIFGIGLIPTGSKDPFALR 481
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 482 RAALGVLRIIVEKNLDLDLQTLTEEAVRLYGEKLTNANVVDDVIDFMLGRFRAWYQDEGYGVDTIQAVLARRPTRPADFD 561
Cdd:COG0751  482 RAALGILRILIEKGLPLDLSELLDAALALYGEQLDAEEVVEEVLDFFLERLRNLLQEEGISYDVVDAVLALGPDDPLDAD 561
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 562 ARMKAVSHFRTLEESSALAAANKRVSNILAKSDETLNDIVHASVLKEAAEIKLAGNLVVLRDKLQPYFAAGRYQDALIEL 641
Cdd:COG0751  562 ARAKALAAFRALPEFEALAAANKRVANILKKAEGEVSAEVDPALLEEPAEKALYEALEELEPEVEALLAAGDYEEALAAL 641
                        650       660       670       680
                 ....*....|....*....|....*....|....*....|....*...
gi 489011585 642 AALREPVDEFFENVMVNAEDKDVRINRLTLLSKLRELFLQVADISLLQ 689
Cdd:COG0751  642 AALRPPVDAFFDNVMVMAEDEALRANRLALLARLRALFLRVADISKLV 689
 
Name Accession Description Interval E-value
GlyS COG0751
Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; ...
4-689 0e+00

Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; Glycyl-tRNA synthetase, beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 440514 [Multi-domain]  Cd Length: 690  Bit Score: 1145.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585   4 NTFLVEIGTEELPPKALRSLAESFAANVTAELDNAGLAHGKVEWFAAPRRLALKVANLAAAQADREVEKRGPAIAQAFDA 83
Cdd:COG0751    3 KDLLLEIGTEELPAKFLPKLLEQLAELLAAGLKEARLSFGEVEVYATPRRLAVLVEGLAEKQPDREEEVKGPPVKAAFDA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  84 EGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMIASSLAKLPIPKLMRWGASDVHFVRPVHT 163
Cdd:COG0751   83 DGNPTKAALGFARSQGVDVDDLERRETDKGEYLFARKTIKGRPTAELLPEILPEAIAKLPFPKSMRWGDGDVRFVRPVRW 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 164 VTLLLGDKVIPATILGIPSDRVIRGHRFMGEPEFTIDHADQYPQILlERGKVIADYEQRKAKIKADAQEAARKIGGQADL 243
Cdd:COG0751  163 LVALLGDEVVPFEILGLKSGRTTRGHRFLGPGPIEIASADDYEETL-REGYVIADFEERRELIREQLEAAAAELGGTADI 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 244 SESLLEEVTSLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPQQIISGNEKVV 323
Cdd:COG0751  242 DEDLLDEVTNLVEWPTALLGSFDEEFLELPQEVLITTMKEHQRYFPVLDADGKLLPYFITVSNGESKDPENVIAGNERVL 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 324 RPRLADAEFFFNTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWIAEQIGAD--VNHATRAGLLSKCDLMTNM 401
Cdd:COG0751  322 RARLADAKFFYEEDLKKPLEDRVEKLKKVVFQEKLGTLADKVERIEALAAAIAEQLGLDeeAALAERAALLAKADLVTQM 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 402 VFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDALPSNPVACAVAIADKMDTLAGIFGIGQHPKGDKDPFALR 481
Cdd:COG0751  402 VGEFPELQGIMGRYYALHDGEPEEVALAIEEHYLPRFAGDALPSTLVGAIVALADKLDTLVGIFGIGLIPTGSKDPFALR 481
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 482 RAALGVLRIIVEKNLDLDLQTLTEEAVRLYGEKLTNANVVDDVIDFMLGRFRAWYQDEGYGVDTIQAVLARRPTRPADFD 561
Cdd:COG0751  482 RAALGILRILIEKGLPLDLSELLDAALALYGEQLDAEEVVEEVLDFFLERLRNLLQEEGISYDVVDAVLALGPDDPLDAD 561
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 562 ARMKAVSHFRTLEESSALAAANKRVSNILAKSDETLNDIVHASVLKEAAEIKLAGNLVVLRDKLQPYFAAGRYQDALIEL 641
Cdd:COG0751  562 ARAKALAAFRALPEFEALAAANKRVANILKKAEGEVSAEVDPALLEEPAEKALYEALEELEPEVEALLAAGDYEEALAAL 641
                        650       660       670       680
                 ....*....|....*....|....*....|....*....|....*...
gi 489011585 642 AALREPVDEFFENVMVNAEDKDVRINRLTLLSKLRELFLQVADISLLQ 689
Cdd:COG0751  642 AALRPPVDAFFDNVMVMAEDEALRANRLALLARLRALFLRVADISKLV 689
glyS TIGR00211
glycyl-tRNA synthetase, tetrameric type, beta subunit; The glycyl-tRNA synthetases differ even ...
1-689 0e+00

glycyl-tRNA synthetase, tetrameric type, beta subunit; The glycyl-tRNA synthetases differ even among the eubacteria in oligomeric structure. In Escherichia coli and most others, it is a heterodimer of two alpha chains and two beta chains, encoded by tandem genes. The genes are similar, but fused, in Chlamydia trachomatis. By contrast, the glycyl-tRNA synthetases of Thermus thermophilus and of archaea and eukaryotes differ considerably; they are homodimeric, mutually similar, and not detected by this model. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272962 [Multi-domain]  Cd Length: 691  Bit Score: 1097.54  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585    1 MSENTFLVEIGTEELPPKALRSLAESFAANVTAELDNAGLAHGKVEWFAAPRRLALKVANLAAAQADREVEKRGPAIAQA 80
Cdd:TIGR00211   1 MSSQTFLVEIGTEELPAKALRSLATQFADKLTAELNKAGLEHGNVEIFATPRRLAVLVKDLAELQPDRKEEKKGPAVKIA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585   81 FDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMIASSLAKLPIPKLMRWGASDVHFVRP 160
Cdd:TIGR00211  81 FDADGKPTKAALGFAKGQGINVEDAEIFQTDKGEWLFVRKIHEGQPTKDLLPPLVLEFLAKLPFPKSMRWGNVDVRFIRP 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  161 VHTVTLLLGDKVIPATILGIPSDRVIRGHRFMGEPEFTIDHADQYPQILLERGkVIADYEQRKAKIKADAQEAARKIGGQ 240
Cdd:TIGR00211 161 IHWIVVLLGDDVIPIEILNVKSDRTTRGHRFLGEDEVSIESPDAYPEQLKENH-VIADPKERKAMILQQIETLAAKLGGI 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  241 ADLSESLLEEVTSLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPQQIISGNE 320
Cdd:TIGR00211 240 ADIDEDLLDEVVSLVEYPTALLGKFEEEFLSLPAEVLVTTMKEHQRYFPVYDKDGKLLPHFITVSNGNSKDPQKIILGNE 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  321 KVVRPRLADAEFFFNTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVN---HATRAGLLSKCDL 397
Cdd:TIGR00211 320 KVLRARLSDAEFFYKTDLKKPLDDNLPRLETVVFQQELGTLKDKVDRISIIAGYIAQQLGADENmleHVKRAALLSKADL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  398 MTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDALPSNPVACAVAIADKMDTLAGIFGIGQHPKGDKDP 477
Cdd:TIGR00211 400 VTNMVYEFPELQGIMGEKYARHDGEDEAVAVAVNEQYLPRSAGDDLPSSLVGSVVAMADKLDTLASIFGIGQIPTGSKDP 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  478 FALRRAALGVLRIIVEKNLDLDLQTLTEEAVRLYGEKLTNANVVDDVIDFMLGRFRAWYQDEGYGVDTIQAVLARRPTRP 557
Cdd:TIGR00211 480 FALRRAALGVLRIIVEKNLEIDLEELLTNFVLLQGDKLTNSNVLEDLEDFFLQRFRALLQDEGIDVDVIQAVLARRETDP 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  558 ADFDARMKAVSHFRTLEESSALAAANKRVSNILAKSDETLNDIVHASVLKEAAEIKLAGNLVVLRDKLQPYFAAGRYQDA 637
Cdd:TIGR00211 560 ADFDARAQALSHFRDLPKAEALAAANKRVANILKKGNPVLSSEIQANLFKEPKEKALFEAVLAIKMNAQESFESGDYETA 639
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|..
gi 489011585  638 LIELAALREPVDEFFENVMVNAEDKDVRINRLTLLSKLRELFLQVADISLLQ 689
Cdd:TIGR00211 640 LEALAELRAPVDEFFDSVMVMADDIELRQNRLNFLWGLRQLFLEVADISALQ 691
tRNA_synt_2f pfam02092
Glycyl-tRNA synthetase beta subunit;
6-551 0e+00

Glycyl-tRNA synthetase beta subunit;


Pssm-ID: 460442  Cd Length: 536  Bit Score: 868.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585    6 FLVEIGTEELPPKALRSLAESFAANVTAELDNAGLAHGKVEWFAAPRRLALKVANLAAAQADREVEKRGPAIAQAFDAEG 85
Cdd:pfam02092   1 LLLEIGTEELPARFLPKALEQLAELITKLLKEARLSYGEVKVFATPRRLAVLVEGLAEKQPDREEEVKGPPVKAAFDADG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585   86 KPSKAAEGWARGCGITVDQAERLTTdKGEWLLYRAHVKGESTEALLPNMIASSLAKLPIPKLMRWGASDVHFVRPVHTVT 165
Cdd:pfam02092  81 NPTKAAEGFARSQGVSVEDLEIREK-KGEYLFARKTEPGRPTAELLPEILPEAIASLPFPKSMRWGDGDLRFVRPIRWLV 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  166 LLLGDKVIPATILGIPSDRVIRGHRFMGEPEFTIDHADQYPQILLERgKVIADYEQRKAKIKADAQEAARKIGGQADLSE 245
Cdd:pfam02092 160 ALLGDEVVPFEILGIKSGRTTRGHRFLGPGPIEIASADDYEEKLREA-FVIADPEERREIILEQIEALAAEAGGTVDIDE 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  246 SLLEEVTSLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPQQIISGNEKVVRP 325
Cdd:pfam02092 239 DLLDEVTNLVEYPTALLGSFDEEFLELPEEVLITSMKEHQRYFPVRDADGKLLPYFITVSNGDPDDPENVIAGNERVLRA 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  326 RLADAEFFFNTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWIAEQIGAdvnhATRAGLLSKCDLMTNMVFEF 405
Cdd:pfam02092 319 RLADAKFFYEEDLKKPLESRVEKLKKVVFQEKLGTLADKVERIEALAAYLAEQLGD----AERAALLAKADLVTEMVGEF 394
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  406 TDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDALPSNPVACAVAIADKMDTLAGIFGIGQHPKGDKDPFALRRAAL 485
Cdd:pfam02092 395 PELQGIMGRYYALADGEDEEVALAIEEHYLPRFAGDALPSTLVGAVVALADKLDTLVGIFGIGLIPTGSKDPFALRRAAL 474
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489011585  486 GVLRIIVEKNLDLDLQTLTEEAVRLYGEkltnANVVDDVIDFMLGRFRAWYQDEGYGVDTIQAVLA 551
Cdd:pfam02092 475 GIIRILLEKGLDLDLRELLEKALELYGD----EEVLADLLEFFLDRLKNLLREEGIRYDVVDAVLA 536
PRK14908 PRK14908
glycine--tRNA ligase;
5-688 2.79e-173

glycine--tRNA ligase;


Pssm-ID: 237859 [Multi-domain]  Cd Length: 1000  Bit Score: 521.50  E-value: 2.79e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585    5 TFLVEIGTEELPPKALRSLAESFAANVTAELDNAGLAHGKVEWFAAPRRLALKVANLAAAQADREVEKRGPAIAQAFDAE 84
Cdd:PRK14908  313 TLLFEIGSEELPATFVPIGIQQLESALRELLADTRLGYEKLEVLGTPRRLALLVEDVAPREPDAEREKRGPRLSAAFDAD 392
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585   85 GKPSKAAEGWARGCGITVDQAERLTTD---------KGEWLLYRAHVKGESTEALLPNMIASSLAKLPIPKLMRWGASDV 155
Cdd:PRK14908  393 GTPTPAGEGFFRSQGVDISHLSALDQDgaieireinGVEYLFLVRPEPGRDAAAILANELPELIQSLRFPKKMRWDDPGL 472
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  156 HFVRPVHTVTLLLGDKVIPATILGIPSDRVIRGHRFMGEPEFTIDHADQYPQILLERGkVIADYEQRKAKIKADAQEAAR 235
Cdd:PRK14908  473 SYARPIRWLVALYGDQIVPISVGTLASGRTTRGHRQLDPPPVEIPSADGYVETLRQAC-VILSPKERREIIVQGLQNLAA 551
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  236 KIGGQADLSESLLEEVTSLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDpqQI 315
Cdd:PRK14908  552 DVQIDAIAEPRLIDEVTNLVEHPFVILGQFDEKFLELPKELLIAEMVKHQRYFPVRDAQGTLLNHFVIVADGSPDD--EI 629
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  316 ISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWIAEQIG-ADVNHATRAGLLSK 394
Cdd:PRK14908  630 VRGNEKVLRARLTDGAFLFKADLKTPLETFVEKLKSVTYFEALGSLADKVERIKAHAEELAALLPlSARETLDRAAELCK 709
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  395 CDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDALPSNPVACAVAIADKMDTLAGIFGIGQHPKGD 474
Cdd:PRK14908  710 FDLVSQMVNEFPELQGIMGRYYAQRAGEPEAVAQALGEHELPRTAGDSLPASTTGALLSLADRLDNLLGCFALGLKPTSS 789
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  475 KDPFALRRAALGVLRIIVEKNLDLDLQTLTEEAVRLYGEKL--TNANVVDDVIDFMLGRFRAWYQDEGYGVDTIQAVLAR 552
Cdd:PRK14908  790 SDPYALRRQALGVLTLLRATPASLDLEDLLARLARHFPSTTvwVKEAVLDEVLEFVWGRLKTQLLDLGFDKDEIAAVLPD 869
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  553 RPTRPADFDARMKAVSHFRTLEESSALAAANKRVSNILAKSDETLNDivhASVLKEAAEIKLAGNLvvlrDKLQPYFAAG 632
Cdd:PRK14908  870 ACKNPAEADKTAQALQELKSTEIFAEIAAALNRLKRILASLSFSVTD---ASLLLEPAELNLKQAL----DAFREELTEL 942
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 489011585  633 --RYQDALIELAALREPVDEFFENVMVNAEDKDVRINRLTLLSKLRELFLQVADISLL 688
Cdd:PRK14908  943 piDLKDYVAAAAELPQAVNTFFDEVLVMADDEAIRNARLGLLAAIRDLKFGVLDWDAL 1000
 
Name Accession Description Interval E-value
GlyS COG0751
Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; ...
4-689 0e+00

Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; Glycyl-tRNA synthetase, beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 440514 [Multi-domain]  Cd Length: 690  Bit Score: 1145.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585   4 NTFLVEIGTEELPPKALRSLAESFAANVTAELDNAGLAHGKVEWFAAPRRLALKVANLAAAQADREVEKRGPAIAQAFDA 83
Cdd:COG0751    3 KDLLLEIGTEELPAKFLPKLLEQLAELLAAGLKEARLSFGEVEVYATPRRLAVLVEGLAEKQPDREEEVKGPPVKAAFDA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  84 EGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMIASSLAKLPIPKLMRWGASDVHFVRPVHT 163
Cdd:COG0751   83 DGNPTKAALGFARSQGVDVDDLERRETDKGEYLFARKTIKGRPTAELLPEILPEAIAKLPFPKSMRWGDGDVRFVRPVRW 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 164 VTLLLGDKVIPATILGIPSDRVIRGHRFMGEPEFTIDHADQYPQILlERGKVIADYEQRKAKIKADAQEAARKIGGQADL 243
Cdd:COG0751  163 LVALLGDEVVPFEILGLKSGRTTRGHRFLGPGPIEIASADDYEETL-REGYVIADFEERRELIREQLEAAAAELGGTADI 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 244 SESLLEEVTSLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPQQIISGNEKVV 323
Cdd:COG0751  242 DEDLLDEVTNLVEWPTALLGSFDEEFLELPQEVLITTMKEHQRYFPVLDADGKLLPYFITVSNGESKDPENVIAGNERVL 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 324 RPRLADAEFFFNTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWIAEQIGAD--VNHATRAGLLSKCDLMTNM 401
Cdd:COG0751  322 RARLADAKFFYEEDLKKPLEDRVEKLKKVVFQEKLGTLADKVERIEALAAAIAEQLGLDeeAALAERAALLAKADLVTQM 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 402 VFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDALPSNPVACAVAIADKMDTLAGIFGIGQHPKGDKDPFALR 481
Cdd:COG0751  402 VGEFPELQGIMGRYYALHDGEPEEVALAIEEHYLPRFAGDALPSTLVGAIVALADKLDTLVGIFGIGLIPTGSKDPFALR 481
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 482 RAALGVLRIIVEKNLDLDLQTLTEEAVRLYGEKLTNANVVDDVIDFMLGRFRAWYQDEGYGVDTIQAVLARRPTRPADFD 561
Cdd:COG0751  482 RAALGILRILIEKGLPLDLSELLDAALALYGEQLDAEEVVEEVLDFFLERLRNLLQEEGISYDVVDAVLALGPDDPLDAD 561
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585 562 ARMKAVSHFRTLEESSALAAANKRVSNILAKSDETLNDIVHASVLKEAAEIKLAGNLVVLRDKLQPYFAAGRYQDALIEL 641
Cdd:COG0751  562 ARAKALAAFRALPEFEALAAANKRVANILKKAEGEVSAEVDPALLEEPAEKALYEALEELEPEVEALLAAGDYEEALAAL 641
                        650       660       670       680
                 ....*....|....*....|....*....|....*....|....*...
gi 489011585 642 AALREPVDEFFENVMVNAEDKDVRINRLTLLSKLRELFLQVADISLLQ 689
Cdd:COG0751  642 AALRPPVDAFFDNVMVMAEDEALRANRLALLARLRALFLRVADISKLV 689
glyS TIGR00211
glycyl-tRNA synthetase, tetrameric type, beta subunit; The glycyl-tRNA synthetases differ even ...
1-689 0e+00

glycyl-tRNA synthetase, tetrameric type, beta subunit; The glycyl-tRNA synthetases differ even among the eubacteria in oligomeric structure. In Escherichia coli and most others, it is a heterodimer of two alpha chains and two beta chains, encoded by tandem genes. The genes are similar, but fused, in Chlamydia trachomatis. By contrast, the glycyl-tRNA synthetases of Thermus thermophilus and of archaea and eukaryotes differ considerably; they are homodimeric, mutually similar, and not detected by this model. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272962 [Multi-domain]  Cd Length: 691  Bit Score: 1097.54  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585    1 MSENTFLVEIGTEELPPKALRSLAESFAANVTAELDNAGLAHGKVEWFAAPRRLALKVANLAAAQADREVEKRGPAIAQA 80
Cdd:TIGR00211   1 MSSQTFLVEIGTEELPAKALRSLATQFADKLTAELNKAGLEHGNVEIFATPRRLAVLVKDLAELQPDRKEEKKGPAVKIA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585   81 FDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMIASSLAKLPIPKLMRWGASDVHFVRP 160
Cdd:TIGR00211  81 FDADGKPTKAALGFAKGQGINVEDAEIFQTDKGEWLFVRKIHEGQPTKDLLPPLVLEFLAKLPFPKSMRWGNVDVRFIRP 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  161 VHTVTLLLGDKVIPATILGIPSDRVIRGHRFMGEPEFTIDHADQYPQILLERGkVIADYEQRKAKIKADAQEAARKIGGQ 240
Cdd:TIGR00211 161 IHWIVVLLGDDVIPIEILNVKSDRTTRGHRFLGEDEVSIESPDAYPEQLKENH-VIADPKERKAMILQQIETLAAKLGGI 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  241 ADLSESLLEEVTSLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPQQIISGNE 320
Cdd:TIGR00211 240 ADIDEDLLDEVVSLVEYPTALLGKFEEEFLSLPAEVLVTTMKEHQRYFPVYDKDGKLLPHFITVSNGNSKDPQKIILGNE 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  321 KVVRPRLADAEFFFNTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVN---HATRAGLLSKCDL 397
Cdd:TIGR00211 320 KVLRARLSDAEFFYKTDLKKPLDDNLPRLETVVFQQELGTLKDKVDRISIIAGYIAQQLGADENmleHVKRAALLSKADL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  398 MTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDALPSNPVACAVAIADKMDTLAGIFGIGQHPKGDKDP 477
Cdd:TIGR00211 400 VTNMVYEFPELQGIMGEKYARHDGEDEAVAVAVNEQYLPRSAGDDLPSSLVGSVVAMADKLDTLASIFGIGQIPTGSKDP 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  478 FALRRAALGVLRIIVEKNLDLDLQTLTEEAVRLYGEKLTNANVVDDVIDFMLGRFRAWYQDEGYGVDTIQAVLARRPTRP 557
Cdd:TIGR00211 480 FALRRAALGVLRIIVEKNLEIDLEELLTNFVLLQGDKLTNSNVLEDLEDFFLQRFRALLQDEGIDVDVIQAVLARRETDP 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  558 ADFDARMKAVSHFRTLEESSALAAANKRVSNILAKSDETLNDIVHASVLKEAAEIKLAGNLVVLRDKLQPYFAAGRYQDA 637
Cdd:TIGR00211 560 ADFDARAQALSHFRDLPKAEALAAANKRVANILKKGNPVLSSEIQANLFKEPKEKALFEAVLAIKMNAQESFESGDYETA 639
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|..
gi 489011585  638 LIELAALREPVDEFFENVMVNAEDKDVRINRLTLLSKLRELFLQVADISLLQ 689
Cdd:TIGR00211 640 LEALAELRAPVDEFFDSVMVMADDIELRQNRLNFLWGLRQLFLEVADISALQ 691
tRNA_synt_2f pfam02092
Glycyl-tRNA synthetase beta subunit;
6-551 0e+00

Glycyl-tRNA synthetase beta subunit;


Pssm-ID: 460442  Cd Length: 536  Bit Score: 868.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585    6 FLVEIGTEELPPKALRSLAESFAANVTAELDNAGLAHGKVEWFAAPRRLALKVANLAAAQADREVEKRGPAIAQAFDAEG 85
Cdd:pfam02092   1 LLLEIGTEELPARFLPKALEQLAELITKLLKEARLSYGEVKVFATPRRLAVLVEGLAEKQPDREEEVKGPPVKAAFDADG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585   86 KPSKAAEGWARGCGITVDQAERLTTdKGEWLLYRAHVKGESTEALLPNMIASSLAKLPIPKLMRWGASDVHFVRPVHTVT 165
Cdd:pfam02092  81 NPTKAAEGFARSQGVSVEDLEIREK-KGEYLFARKTEPGRPTAELLPEILPEAIASLPFPKSMRWGDGDLRFVRPIRWLV 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  166 LLLGDKVIPATILGIPSDRVIRGHRFMGEPEFTIDHADQYPQILLERgKVIADYEQRKAKIKADAQEAARKIGGQADLSE 245
Cdd:pfam02092 160 ALLGDEVVPFEILGIKSGRTTRGHRFLGPGPIEIASADDYEEKLREA-FVIADPEERREIILEQIEALAAEAGGTVDIDE 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  246 SLLEEVTSLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPQQIISGNEKVVRP 325
Cdd:pfam02092 239 DLLDEVTNLVEYPTALLGSFDEEFLELPEEVLITSMKEHQRYFPVRDADGKLLPYFITVSNGDPDDPENVIAGNERVLRA 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  326 RLADAEFFFNTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWIAEQIGAdvnhATRAGLLSKCDLMTNMVFEF 405
Cdd:pfam02092 319 RLADAKFFYEEDLKKPLESRVEKLKKVVFQEKLGTLADKVERIEALAAYLAEQLGD----AERAALLAKADLVTEMVGEF 394
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  406 TDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDALPSNPVACAVAIADKMDTLAGIFGIGQHPKGDKDPFALRRAAL 485
Cdd:pfam02092 395 PELQGIMGRYYALADGEDEEVALAIEEHYLPRFAGDALPSTLVGAVVALADKLDTLVGIFGIGLIPTGSKDPFALRRAAL 474
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489011585  486 GVLRIIVEKNLDLDLQTLTEEAVRLYGEkltnANVVDDVIDFMLGRFRAWYQDEGYGVDTIQAVLA 551
Cdd:pfam02092 475 GIIRILLEKGLDLDLRELLEKALELYGD----EEVLADLLEFFLDRLKNLLREEGIRYDVVDAVLA 536
PRK14908 PRK14908
glycine--tRNA ligase;
5-688 2.79e-173

glycine--tRNA ligase;


Pssm-ID: 237859 [Multi-domain]  Cd Length: 1000  Bit Score: 521.50  E-value: 2.79e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585    5 TFLVEIGTEELPPKALRSLAESFAANVTAELDNAGLAHGKVEWFAAPRRLALKVANLAAAQADREVEKRGPAIAQAFDAE 84
Cdd:PRK14908  313 TLLFEIGSEELPATFVPIGIQQLESALRELLADTRLGYEKLEVLGTPRRLALLVEDVAPREPDAEREKRGPRLSAAFDAD 392
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585   85 GKPSKAAEGWARGCGITVDQAERLTTD---------KGEWLLYRAHVKGESTEALLPNMIASSLAKLPIPKLMRWGASDV 155
Cdd:PRK14908  393 GTPTPAGEGFFRSQGVDISHLSALDQDgaieireinGVEYLFLVRPEPGRDAAAILANELPELIQSLRFPKKMRWDDPGL 472
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  156 HFVRPVHTVTLLLGDKVIPATILGIPSDRVIRGHRFMGEPEFTIDHADQYPQILLERGkVIADYEQRKAKIKADAQEAAR 235
Cdd:PRK14908  473 SYARPIRWLVALYGDQIVPISVGTLASGRTTRGHRQLDPPPVEIPSADGYVETLRQAC-VILSPKERREIIVQGLQNLAA 551
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  236 KIGGQADLSESLLEEVTSLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDpqQI 315
Cdd:PRK14908  552 DVQIDAIAEPRLIDEVTNLVEHPFVILGQFDEKFLELPKELLIAEMVKHQRYFPVRDAQGTLLNHFVIVADGSPDD--EI 629
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  316 ISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWIAEQIG-ADVNHATRAGLLSK 394
Cdd:PRK14908  630 VRGNEKVLRARLTDGAFLFKADLKTPLETFVEKLKSVTYFEALGSLADKVERIKAHAEELAALLPlSARETLDRAAELCK 709
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  395 CDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDALPSNPVACAVAIADKMDTLAGIFGIGQHPKGD 474
Cdd:PRK14908  710 FDLVSQMVNEFPELQGIMGRYYAQRAGEPEAVAQALGEHELPRTAGDSLPASTTGALLSLADRLDNLLGCFALGLKPTSS 789
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  475 KDPFALRRAALGVLRIIVEKNLDLDLQTLTEEAVRLYGEKL--TNANVVDDVIDFMLGRFRAWYQDEGYGVDTIQAVLAR 552
Cdd:PRK14908  790 SDPYALRRQALGVLTLLRATPASLDLEDLLARLARHFPSTTvwVKEAVLDEVLEFVWGRLKTQLLDLGFDKDEIAAVLPD 869
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  553 RPTRPADFDARMKAVSHFRTLEESSALAAANKRVSNILAKSDETLNDivhASVLKEAAEIKLAGNLvvlrDKLQPYFAAG 632
Cdd:PRK14908  870 ACKNPAEADKTAQALQELKSTEIFAEIAAALNRLKRILASLSFSVTD---ASLLLEPAELNLKQAL----DAFREELTEL 942
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 489011585  633 --RYQDALIELAALREPVDEFFENVMVNAEDKDVRINRLTLLSKLRELFLQVADISLL 688
Cdd:PRK14908  943 piDLKDYVAAAAELPQAVNTFFDEVLVMADDEAIRNARLGLLAAIRDLKFGVLDWDAL 1000
DALR_1 pfam05746
DALR anticodon binding domain; This all alpha helical domain is the anticodon binding domain ...
582-679 3.71e-08

DALR anticodon binding domain; This all alpha helical domain is the anticodon binding domain in Arginyl and glycyl tRNA synthetase. This domain is known as the DALR domain after characteriztic conserved amino acids.


Pssm-ID: 399042 [Multi-domain]  Cd Length: 117  Bit Score: 52.27  E-value: 3.71e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011585  582 ANKRVSNILAKSDE-TLNDIVHASVLKEAAEIKLAGNL-----VVLR--DKLQPYFAAgryqDALIELAALrepVDEFFE 653
Cdd:pfam05746   4 AHARICSILRKAGElGINLDIDADLLTEEEEKELLKALlqfpeVLEEaaEELEPHRLA----NYLYELASA---FHSFYN 76
                          90       100
                  ....*....|....*....|....*.
gi 489011585  654 NVMVNAEDKDVRINRLTLLSKLRELF 679
Cdd:pfam05746  77 NCRVLDEDNEERNARLALLKAVRQVL 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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