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Conserved domains on  [gi|488992311|ref|WP_002903059|]
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MULTISPECIES: amino acid permease [Klebsiella]

Protein Classification

APC family permease( domain architecture ID 1903533)

APC (amino acid/polyamine/organocation) family permease is involved in the uptake of a specific amino acid and/or polyamine substrate with the concomitant import of a proton

Gene Ontology:  GO:0055085|GO:0022857
PubMed:  24038584|25043943|10931886
TCDB:  2.A.3

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
AA_permease_2 super family cl45918
Amino acid permease;
1-465 0e+00

Amino acid permease;


The actual alignment was detected with superfamily member PRK11049:

Pssm-ID: 459263  Cd Length: 469  Bit Score: 547.41  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   1 MTEHQHQASPAAGGEgaSQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLL 80
Cdd:PRK11049   1 VDQVKVVADDQAPAE--QSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  81 TRHDYRSFADFVGEYLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGE 160
Cdd:PRK11049  79 SNLEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 161 AEFWFALIKVITIIALIGTGGWMIATGWTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETR 240
Cdd:PRK11049 159 MEFWFAMIKIVAIVALIVVGLVMVAMHFQSPTGVEASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETK 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 241 DPQRILPKAINALPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSST 320
Cdd:PRK11049 239 DPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTS 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 321 RMLYGLSVEKHAHWQFRILSRSTrIPVRSLLFSCFCMLIGTLLLFLVPNVMTLFTIVSTLAAIMVVFSWGMILVAYLVYR 400
Cdd:PRK11049 319 RMLFGLAQEGVAPKAFAKLSKRA-VPAKGLTFSCICLLGGVVLLYVNPSVIGAFTLVTTVSAILFMFVWTIILCSYLVYR 397

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488992311 401 RQRPDLHAGSIFKMPAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASPLWFIAL-WGFWKLKQRR 465
Cdd:PRK11049 398 KQRPHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWFIALgLGYLFIGKKR 463
 
Name Accession Description Interval E-value
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
 1-465 0e+00

D-alanine/D-serine/glycine permease; Provisional


Pssm-ID: 236830  Cd Length: 469  Bit Score: 547.41  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   1 MTEHQHQASPAAGGEgaSQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLL 80
Cdd:PRK11049   1 VDQVKVVADDQAPAE--QSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  81 TRHDYRSFADFVGEYLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGE 160
Cdd:PRK11049  79 SNLEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 161 AEFWFALIKVITIIALIGTGGWMIATGWTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETR 240
Cdd:PRK11049 159 MEFWFAMIKIVAIVALIVVGLVMVAMHFQSPTGVEASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETK 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 241 DPQRILPKAINALPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSST 320
Cdd:PRK11049 239 DPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTS 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 321 RMLYGLSVEKHAHWQFRILSRSTrIPVRSLLFSCFCMLIGTLLLFLVPNVMTLFTIVSTLAAIMVVFSWGMILVAYLVYR 400
Cdd:PRK11049 319 RMLFGLAQEGVAPKAFAKLSKRA-VPAKGLTFSCICLLGGVVLLYVNPSVIGAFTLVTTVSAILFMFVWTIILCSYLVYR 397

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488992311 401 RQRPDLHAGSIFKMPAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASPLWFIAL-WGFWKLKQRR 465
Cdd:PRK11049 398 KQRPHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWFIALgLGYLFIGKKR 463
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
9-467 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 532.39  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   9 SPAAGGEGASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSF 88
Cdd:COG1113    2 STSAAASEEEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  89 ADFVGEYLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALI 168
Cdd:COG1113   82 SDYAREYLGPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 169 KVITIIALIGTGGWMIATGWTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPK 248
Cdd:COG1113  162 KVVAIVAFIVVGLLLIFFGFGLPGGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPK 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 249 AINALPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSV 328
Cdd:COG1113  242 AINSVIWRILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAE 321

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 329 EKHAHWQFRILSRStRIPVRSLLFSCFCMLIGTLLLFLVPNvmTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQRPDLHA 408
Cdd:COG1113  322 RGDAPKFFGKLSKR-GVPVRAILLSAVVLLIGVVLNYLLPE--KAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREGA 398

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 409 G-SIFKMPAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASPLWFIALWGFWKLKQRREG 467
Cdd:COG1113  399 AaLKFKMPGFPYTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFLVRRRRA 458
AA_permease pfam00324
Amino acid permease;
28-465 7.24e-74

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 240.30  E-value: 7.24e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   28 HIQMIALGGAIGTGLFMGAGRNIAVAG-TSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGEYLGPQASFYLGW 106
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGpAGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  107 TYWLSWVVTCIADVVVCGSYMQYW--FPELS-AWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITIIALIGTGGWM 183
Cdd:pfam00324  81 NYWLSWITVLALELTAASILIQFWelVPDIPyLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGIIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  184 IATGWTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINALPLRIIIFYLL 263
Cdd:pfam00324 161 LSGGNPNDGAIFRYLGDNGGKNNFPPGFGKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  264 SMVVIIAVASWPGVSAET------SPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHAHWQFR 337
Cdd:pfam00324 241 SLLAIGLLVPWNDPGLLNdsasaaSPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPKFLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  338 ILSRStRIPVRSLLFSCFCMLIGTLLLFLVPNvmTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQ---RPDLHAGSIFKM 414
Cdd:pfam00324 321 KVDKR-GVPLRAILVSMVISLLALLLASLNPA--IVFNFLLAISGLSGLIVWGLISLSHLRFRKAfkyQGRSIDELPFKA 397

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488992311  415 PAGVVMSWVSLLFFAFAIFIMIFDPDT-------------LLALLASPLWFIALWGFWKLKQRR 465
Cdd:pfam00324 398 PLGPLGVILGLAAIIIILIIQFLYAFLpvpggpknwgagsFAAAYLIVLLFLIILIGVKLHVKN 461
GABAperm TIGR01773
gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of ...
 17-450 4.21e-67

gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273797  Cd Length: 452  Bit Score: 222.05  E-value: 4.21e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   17 ASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGEYL 96
Cdd:TIGR01773   7 GLKLPNGLKTRHVTMLSIAGVIGAGLFVGSGSAIASAGPAALLAYLLAGLLVVFIMRMLGEMAVANPDTGSFSTYADDAI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   97 GPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITIIAL 176
Cdd:TIGR01773  87 GRWAGFTIGWLYWWFWVLVIPLEAIAAAGILQYWFPDIPLWLFSLILTIVLTLTNLYSVKSYGEFEFWFALIKVIAIIAF 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  177 IGTGGWMIATGWtsPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINALPLR 256
Cdd:TIGR01773 167 IILGAVAIFGFA--PGSEVSGFSNLTGKGGFFPNGIGAVLLAILVTMFSFMGTEIVTIAAAESSNPIKSITRATNSVIWR 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  257 IIIFYLLSMVVIIAVASW--PGVsAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHAHW 334
Cdd:TIGR01773 245 IIVFYLGSIFIVVALLPWnsPNL-LEVGSYVAVLELLGIPHAKLIMDFVVLTAVLSCLNSALYTTSRMLYSLAERGDAPR 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  335 QFRILSRStRIPVRSLLFSCFCMLIGTLLLFLVPNVMTLFTIVSTLAAIMVVFSwgMILVAYLVYRRQRPDLHAGSIFKM 414
Cdd:TIGR01773 324 VFMKLNKK-GVPVQAVLASTFFSFLTVVVNYFAPDKVFLFLVNSSGAIALLVYL--VIAVSQLRMRKKLKANGEAIKIRM 400

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 488992311  415 PAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASPL 450
Cdd:TIGR01773 401 WLYPWLTWLVIIFICGILVSMLFIPSMRDEVLLTGL 436
 
Name Accession Description Interval E-value
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
 1-465 0e+00

D-alanine/D-serine/glycine permease; Provisional


Pssm-ID: 236830  Cd Length: 469  Bit Score: 547.41  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   1 MTEHQHQASPAAGGEgaSQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLL 80
Cdd:PRK11049   1 VDQVKVVADDQAPAE--QSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  81 TRHDYRSFADFVGEYLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGE 160
Cdd:PRK11049  79 SNLEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 161 AEFWFALIKVITIIALIGTGGWMIATGWTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETR 240
Cdd:PRK11049 159 MEFWFAMIKIVAIVALIVVGLVMVAMHFQSPTGVEASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETK 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 241 DPQRILPKAINALPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSST 320
Cdd:PRK11049 239 DPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTS 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 321 RMLYGLSVEKHAHWQFRILSRSTrIPVRSLLFSCFCMLIGTLLLFLVPNVMTLFTIVSTLAAIMVVFSWGMILVAYLVYR 400
Cdd:PRK11049 319 RMLFGLAQEGVAPKAFAKLSKRA-VPAKGLTFSCICLLGGVVLLYVNPSVIGAFTLVTTVSAILFMFVWTIILCSYLVYR 397

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488992311 401 RQRPDLHAGSIFKMPAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASPLWFIAL-WGFWKLKQRR 465
Cdd:PRK11049 398 KQRPHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWFIALgLGYLFIGKKR 463
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
9-467 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 532.39  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   9 SPAAGGEGASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSF 88
Cdd:COG1113    2 STSAAASEEEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  89 ADFVGEYLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALI 168
Cdd:COG1113   82 SDYAREYLGPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 169 KVITIIALIGTGGWMIATGWTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPK 248
Cdd:COG1113  162 KVVAIVAFIVVGLLLIFFGFGLPGGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTIPK 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 249 AINALPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSV 328
Cdd:COG1113  242 AINSVIWRILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSLAE 321

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 329 EKHAHWQFRILSRStRIPVRSLLFSCFCMLIGTLLLFLVPNvmTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQRPDLHA 408
Cdd:COG1113  322 RGDAPKFFGKLSKR-GVPVRAILLSAVVLLIGVVLNYLLPE--KAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREGA 398

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 409 G-SIFKMPAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASPLWFIALWGFWKLKQRREG 467
Cdd:COG1113  399 AaLKFKMPGFPYTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFLVRRRRA 458
LysP COG0833
Amino acid permease [Amino acid transport and metabolism];
11-465 1.52e-103

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440595 [Multi-domain]  Cd Length: 467  Bit Score: 316.73  E-value: 1.52e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  11 AAGGEGASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAG-TSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFA 89
Cdd:COG0833    1 SSGSEKQNKLKRGLKSRHLSMIALGGVIGTGLFLASGYTISQAGpGGALLAYLLGGLMVYFLMTSLGELAVAMPVSGSFQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  90 DFVGEYLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIK 169
Cdd:COG0833   81 TYATRFIDPAFGFAVGWNYWLNWAITVAAELTAAGIIMQYWFPDVPVWIWSLLFLALIFLLNALSVKAFGESEFWFSLIK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 170 VITIIALIGTGGWMIAtGWTSpdGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKA 249
Cdd:COG0833  161 VITVIAFIIVGLLMIF-GIIG--GHAPGFSNFTTGDGPFPGGFLAILGVMMIVGFSFQGTELIGIAAGESENPEKTIPKA 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 250 INALPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVE 329
Cdd:COG0833  238 IRQVFWRILLFYILAIFVIAALIPYTDAGVAESPFTLVFERAGIPYAADIMNAVILTAVLSAGNSGLYASTRMLWSLAKE 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 330 KHAHwqfRILSRSTR--IPVRSLLFScfcMLIGTLLLFL-VPNVMTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQ---- 402
Cdd:COG0833  318 GMAP---KIFAKLNKrgVPLNALLAT---MAVGLLALLSsFFGAGTVYLWLLSISGLTGFIAWLGIAISHYRFRRAyvaq 391

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488992311 403 ---RPDLHagsiFKMPAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASPLWFIALWGFWKLKQRR 465
Cdd:COG0833  392 ggdLEDLK----YKAPLFPFGPIFAFILCLIVIIGQAFDPEQRIALYIGIPFFLACYLGYKLKKKT 453
PRK10238 PRK10238
aromatic amino acid transporter AroP;
13-464 5.73e-96

aromatic amino acid transporter AroP;


Pssm-ID: 182324 [Multi-domain]  Cd Length: 456  Bit Score: 297.25  E-value: 5.73e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  13 GGEGASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFV 92
Cdd:PRK10238   3 GQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  93 GEYLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVIT 172
Cdd:PRK10238  83 YKYWGSFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKVIA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 173 IIALIGTGGWMIATGWTSPDgvtASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINA 252
Cdd:PRK10238 163 VVAMIIFGGWLLFSGNGGPQ---ATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQ 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 253 LPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHA 332
Cdd:PRK10238 240 VIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNA 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 333 HWQFRILSRSTrIPVRSLLFSCFCMLIGTLLLFLVPNvmTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQRPdlHAGSIF 412
Cdd:PRK10238 320 PKALASVDKRG-VPVNTILVSALVTALCVLINYLAPE--SAFGLLMALVVSALVINWAMISLAHMKFRRAKQ--EQGVVT 394

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....
gi 488992311 413 KMPAGV--VMSWVSLLFFAFAIFIMIFDPDTLLALLASPLWFIALWGFWKLKQR 464
Cdd:PRK10238 395 RFPALLypLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEK 448
PRK10249 PRK10249
phenylalanine transporter; Provisional
 8-465 1.96e-90

phenylalanine transporter; Provisional


Pssm-ID: 236667  Cd Length: 458  Bit Score: 283.03  E-value: 1.96e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   8 ASPAAGGEGASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRS 87
Cdd:PRK10249   7 VSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLGIGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGS 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  88 FADFVGEYLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFAL 167
Cdd:PRK10249  87 FAHFAYKYWGPFAGFLSGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGETEFWFAL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 168 IKVITIIALIGTGGWMIATGwtsPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILP 247
Cdd:PRK10249 167 IKVLAIIGMIGFGLWLLFSG---HGGEKASIDNLWRYGGFFATGWNGLILSLAVIMFSFGGLELIGITAAEARDPEKSIP 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 248 KAINALPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLS 327
Cdd:PRK10249 244 KAVNQVVYRILLFYIGSLVVLLALYPWVEVKSNSSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLS 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 328 VEKHAHwqfRILSRSTR--IPVRSLLFSCFCMLIGTLLLFLVPNvmTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQRPD 405
Cdd:PRK10249 324 VQGNAP---KFLTRVSRrgVPINSLMLSGAITSLVVLINYLLPQ--KAFGLLMALVVATLLLNWIMICLAHLRFRAAMRR 398

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 406 LHAGSIFKMPAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASPLWFIALWGFWKLKQRR 465
Cdd:PRK10249 399 QGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFVAFKTLRRK 458
proY PRK10580
putative proline-specific permease; Provisional
 15-470 5.44e-90

putative proline-specific permease; Provisional


Pssm-ID: 182566 [Multi-domain]  Cd Length: 457  Bit Score: 281.71  E-value: 5.44e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  15 EGASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGE 94
Cdd:PRK10580   2 ESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGVAAYIIMRALGEMSVHNPAASSFSRYAQE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  95 YLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITII 174
Cdd:PRK10580  82 NLGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATII 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 175 ALIGTGGWMIATGwTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINALP 254
Cdd:PRK10580 162 IMIVAGIGIIIWG-IGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSVP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 255 LRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHAHW 334
Cdd:PRK10580 241 MRILVFYVGTLFVIMSIYPWNQVGTNGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPK 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 335 QFRILSRSTrIPVRSLLFSCFCMLIGTLLLFLVPNvmTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQRPDLHAGSI-FK 413
Cdd:PRK10580 321 IFSKTSRRG-IPWVTVLVMTTALLFAVYLNYIMPE--NVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALkFK 397

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 488992311 414 MPAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASPLWFIALWGFWKLKQRREGQLQ 470
Cdd:PRK10580 398 VPGGVATTIGGLIFLVFIIGLIGYHPDTRISLYVGFAWIVLLLIGWMFKRRHDRQLA 454
PRK10746 PRK10746
putative transport protein YifK; Provisional
 15-461 2.24e-82

putative transport protein YifK; Provisional


Pssm-ID: 182694  Cd Length: 461  Bit Score: 262.06  E-value: 2.24e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  15 EGASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGE 94
Cdd:PRK10746   3 DNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  95 YLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITII 174
Cdd:PRK10746  83 YMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTII 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 175 ALIGTGGWMIATGWTSpDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINALP 254
Cdd:PRK10746 163 VMIVIGLGVIFFGFGN-GGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKVL 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 255 LRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHAHW 334
Cdd:PRK10746 242 WRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPA 321

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 335 QFRILSRSTrIPVRSLLFSCFCMLIGTLLLFLVPNVMTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQRPDLHAGSIFKm 414
Cdd:PRK10746 322 AMAKVSRHG-VPVAGVAVSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFR- 399

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|
gi 488992311 415 paGVVMSWVSLLFFAFAIFIMI---FDPDTLLALLASPLWFIALWGFWKL 461
Cdd:PRK10746 400 --SILFPWANYLTMAFLICVLIgmyFNEDTRMSLFVGIIFLLAVTLIYKV 447
PRK15049 PRK15049
L-asparagine permease;
22-470 2.57e-76

L-asparagine permease;


Pssm-ID: 185009  Cd Length: 499  Bit Score: 247.61  E-value: 2.57e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  22 RGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGEYLGPQAS 101
Cdd:PRK15049  28 KAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 102 FYLGWTYWLSWVVTCIADVVVCGSYMQYW--FPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITIIALIGT 179
Cdd:PRK15049 108 YVAGWMYFINWAMTGIVDITAVALYMHYWgaFGGVPQWVFALAALTIVGTMNMIGVKWFAEMEFWFALIKVLAIVTFLVV 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 180 GGWMIATGwTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINALPLRIII 259
Cdd:PRK15049 188 GTVFLGSG-QPLDGNTTGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGL 266

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 260 FYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHAHWQFRIL 339
Cdd:PRK15049 267 FYVGSVVLLVMLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMAMGGSAPSFMAKM 346

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 340 SRStRIPVRSLLFSCFCMLIGTLLLFLVPNvmTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQRPDLHAGSI-FKMPAGV 418
Cdd:PRK15049 347 SRQ-HVPYAGILATLVVYVVGVFLNYLVPS--RVFEIVLNFASLGIIASWAFIIVCQMRLRKAIKEGKAADVsFKLPGAP 423

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|...
gi 488992311 419 VMSWVSLLFFAFAIFIMIFD-PDTLLALLASPLWFIALWGFWKLKQRREGQLQ 470
Cdd:PRK15049 424 FTSWLTLLFLLSVLVLMAFDyPNGTYTIAALPIIGILLVIGWFGVRKRVAEIH 476
AA_permease pfam00324
Amino acid permease;
28-465 7.24e-74

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 240.30  E-value: 7.24e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   28 HIQMIALGGAIGTGLFMGAGRNIAVAG-TSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGEYLGPQASFYLGW 106
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGpAGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  107 TYWLSWVVTCIADVVVCGSYMQYW--FPELS-AWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITIIALIGTGGWM 183
Cdd:pfam00324  81 NYWLSWITVLALELTAASILIQFWelVPDIPyLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGIIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  184 IATGWTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINALPLRIIIFYLL 263
Cdd:pfam00324 161 LSGGNPNDGAIFRYLGDNGGKNNFPPGFGKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  264 SMVVIIAVASWPGVSAET------SPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHAHWQFR 337
Cdd:pfam00324 241 SLLAIGLLVPWNDPGLLNdsasaaSPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPKFLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  338 ILSRStRIPVRSLLFSCFCMLIGTLLLFLVPNvmTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQ---RPDLHAGSIFKM 414
Cdd:pfam00324 321 KVDKR-GVPLRAILVSMVISLLALLLASLNPA--IVFNFLLAISGLSGLIVWGLISLSHLRFRKAfkyQGRSIDELPFKA 397

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488992311  415 PAGVVMSWVSLLFFAFAIFIMIFDPDT-------------LLALLASPLWFIALWGFWKLKQRR 465
Cdd:pfam00324 398 PLGPLGVILGLAAIIIILIIQFLYAFLpvpggpknwgagsFAAAYLIVLLFLIILIGVKLHVKN 461
GABAperm TIGR01773
gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of ...
 17-450 4.21e-67

gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273797  Cd Length: 452  Bit Score: 222.05  E-value: 4.21e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   17 ASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGEYL 96
Cdd:TIGR01773   7 GLKLPNGLKTRHVTMLSIAGVIGAGLFVGSGSAIASAGPAALLAYLLAGLLVVFIMRMLGEMAVANPDTGSFSTYADDAI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   97 GPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITIIAL 176
Cdd:TIGR01773  87 GRWAGFTIGWLYWWFWVLVIPLEAIAAAGILQYWFPDIPLWLFSLILTIVLTLTNLYSVKSYGEFEFWFALIKVIAIIAF 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  177 IGTGGWMIATGWtsPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINALPLR 256
Cdd:TIGR01773 167 IILGAVAIFGFA--PGSEVSGFSNLTGKGGFFPNGIGAVLLAILVTMFSFMGTEIVTIAAAESSNPIKSITRATNSVIWR 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  257 IIIFYLLSMVVIIAVASW--PGVsAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHAHW 334
Cdd:TIGR01773 245 IIVFYLGSIFIVVALLPWnsPNL-LEVGSYVAVLELLGIPHAKLIMDFVVLTAVLSCLNSALYTTSRMLYSLAERGDAPR 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  335 QFRILSRStRIPVRSLLFSCFCMLIGTLLLFLVPNVMTLFTIVSTLAAIMVVFSwgMILVAYLVYRRQRPDLHAGSIFKM 414
Cdd:TIGR01773 324 VFMKLNKK-GVPVQAVLASTFFSFLTVVVNYFAPDKVFLFLVNSSGAIALLVYL--VIAVSQLRMRKKLKANGEAIKIRM 400

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 488992311  415 PAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASPL 450
Cdd:TIGR01773 401 WLYPWLTWLVIIFICGILVSMLFIPSMRDEVLLTGL 436
2A0310 TIGR00913
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
 21-437 3.34e-63

amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273334  Cd Length: 478  Bit Score: 212.53  E-value: 3.34e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   21 KRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVI-YVLVGFFTYMVMRAMGEL-LLTRHDYRSFADFVGEYLGP 98
Cdd:TIGR00913   1 KKSLKQRHIQMIALGGTIGTGLLVGSGTALATGGPAGLLIgYAIMGSIIYCVMQSLGEMaTFYPVVSGSFATYASRFVDP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   99 QASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITIIALIG 178
Cdd:TIGR00913  81 AFGFAVGWNYWLQWLIVLPLELVTASMTIQYWTDKVNPAVWIAIFYVFIVIINLFGVKGYGEAEFWFSSIKILAIIGFII 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  179 TGGWMIATGWTSPDGVTASLSHltDPTAFMPHGITGFFAG----FQIAIFSFTGIELLGTMTAETRDPQRILPKAINALP 254
Cdd:TIGR00913 161 LSIILNCGGGPNHGYIGFRYWH--DPGAFAGGTIGGRFKGvcsvFVTAAFSFGGTELVALTAGEAANPRKSIPRAAKRTF 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  255 LRIIIFYLLSMVVIIA---------VASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYG 325
Cdd:TIGR00913 239 WRILVFYILTLFLIGFlvpyndprlLSSSSSSDSAASPFVIAIQNHGIKVLPHIFNAVILISVLSAANSSLYASSRTLYA 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  326 LSVEKHAHWQFRILSRSTRiPVRSLLFSCFCMLIGtlllFLV--PNVMTLFTIVSTLAAIMVVFSWGMILVAYLVYR--- 400
Cdd:TIGR00913 319 LAHQGLAPKIFAYVDRRGV-PYVAVIVSSLFGLLA----FLAvsKKEAEVFTWLLNISGLSGFFTWMCICLSHIRFRkam 393

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 488992311  401 ----RQRPDLhagsIFKMPAGVVMSWVSLLFFAFAIFIMIF 437
Cdd:TIGR00913 394 kaqgRSLDEL----PYKSQTGPYGSYYALFFNILILIAQGY 430
PRK11387 PRK11387
S-methylmethionine permease;
5-465 1.10e-60

S-methylmethionine permease;


Pssm-ID: 236904  Cd Length: 471  Bit Score: 205.86  E-value: 1.10e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   5 QHQASPAAGgegasQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTS-ILVIYVLVGFFTYMVMRAMGELLLTRH 83
Cdd:PRK11387   2 PEPTSQQAG-----QFKRTMKVRHLVMLSLGGVIGTGLFFNTGYIISTTGAAgTLLAYLIGALVVYLVMQCLGELSVAMP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  84 DYRSFADFVGEYLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEF 163
Cdd:PRK11387  77 ETGAFHVYAARYLGPATGYTVAWLYWLTWTVALGSSLTAAGFCMQYWFPQVPVWPWCLLFCALIFGLNVVSTRFFAEGEF 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 164 WFALIKVITIIALIGTGGWMIATGWTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQ 243
Cdd:PRK11387 157 WFSLIKVVTILAFIVLGGAAIFGFIPMQDGSPAPGLRNLTAEGWFPHGGLPILMTMVAVNFAFSGTELIGIAAGETENPA 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 244 RILPKAINALPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRML 323
Cdd:PRK11387 237 KVIPVAIRTTIARLVIFFVGTVLVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADIFNFVILTAILSAANSGLYASGRML 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 324 YGLSVEKHAHWQFRILSRSTrIPVRSLLFScfcMLIGTLLLFL-VPNVMTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQ 402
Cdd:PRK11387 317 WSLSNEGTLPACFARLTKRG-IPLTALSVS---MLGGLLALFSsVVAPDTVFVALSAISGFAVVAVWLSICASHFMFRRR 392

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488992311 403 R-------PDLHagsiFKMPAGVVMSWVSLLFFAFAIFIMIFDPDTLLALLASpLWFIAL-WGFWKLKQRR 465
Cdd:PRK11387 393 HlrdgkalSELA----YRAPWYPLTPILGFVLCLLACVGLAFDPSQRIALWCG-IPFVALcYGAYYLTQRL 458
PRK10836 PRK10836
lysine transporter; Provisional
 20-341 3.25e-54

lysine transporter; Provisional


Pssm-ID: 182767  Cd Length: 489  Bit Score: 188.87  E-value: 3.25e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  20 LKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTS-ILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGEYLGP 98
Cdd:PRK10836  13 LRRELKARHLTMIAIGGSIGTGLFVASGATISQAGPGgALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  99 QASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITIIALIG 178
Cdd:PRK10836  93 GFGFALGWNYWYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFSLIKVTTVIVFII 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 179 TGGWMIATGWTSPDGvtASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINALPLRII 258
Cdd:PRK10836 173 VGVLMIIGIFKGAEP--AGWSNWTIGDAPFAGGFAAMIGVAMIVGFSFQGTELIGIAAGESEDPAKNIPRAVRQVFWRIL 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 259 IFYLLSMVVIIAVASWPGVS--------AETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEK 330
Cdd:PRK10836 251 LFYVFAILIISLIIPYTDPSllrndvkdISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDG 330

                        330
                 ....*....|.
gi 488992311 331 HAHWQFRILSR 341
Cdd:PRK10836 331 KAPRIFAKLSR 341
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
15-469 2.05e-46

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 166.61  E-value: 2.05e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  15 EGASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGE 94
Cdd:COG0531    4 GESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYARR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  95 YLGPQASFYLGWTYWLSWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITII 174
Cdd:COG0531   84 ALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSVLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 175 ALIGTGGWMIATGWTSPdgvtaslshltdptaFMPH--GITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINA 252
Cdd:COG0531  164 LFIVVGLFAFDPANFTP---------------FLPAggGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIIL 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 253 LPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHA 332
Cdd:COG0531  229 SLLIVGVLYILVSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARDGLL 308

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 333 HWQFRILSRSTRIPVRSLLFSCFCMLIGTLLlflvpnVMTLFTIVSTLAAIMVVFSWGMILVAYLVYRRQRPDLHagSIF 412
Cdd:COG0531  309 PKVFAKVHPRFGTPVNAILLTGVIALLLLLL------GAASFTALASLASVGVLLAYLLVALAVIVLRRRRPDLP--RPF 380

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 488992311 413 KMPaGVVMSWVSLLFFAFAIFIMifdpdTLLALLASPLWFIALWGFWKLKQRREGQL 469
Cdd:COG0531  381 RVP-LPLIPILGILLCLFLLYLL-----GPGALLIGLVLLAIGLLLYLLYRRRHPKL 431
PRK10197 PRK10197
GABA permease;
31-450 9.31e-44

GABA permease;


Pssm-ID: 182297  Cd Length: 446  Bit Score: 159.79  E-value: 9.31e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  31 MIALGGAIGTGLFMGAGRNIAVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGEYLGPQASFYLGWTYWL 110
Cdd:PRK10197   1 MLSIAGVIGASLFVGSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 111 SWVVTCIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITIIALIGTGGWMIATGWts 190
Cdd:PRK10197  81 FWVLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKVIAILAFIFLGAVAISGFY-- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 191 PDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINALPLRIIIFYLLSMVVIIA 270
Cdd:PRK10197 159 PYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAEIVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVA 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 271 VASW--PGVSAETSpFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHAHWQFRILSRStRIPVR 348
Cdd:PRK10197 239 LIPWnmPGLKAVGS-YRSVLELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRS-KTPYV 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 349 SLLFSCFCMLIGTLLLFLVPNVMTLFTIVSTLAAIMVVFswgmILVAYLVYRRQRPDLHAGSIFKMPAGVV--MSWVSLL 426
Cdd:PRK10197 317 AVLLSTGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVY----LVIAVSQLRMRKILRAEGSEIRLRMWLYpwLTWLVIG 392

                        410       420
                 ....*....|....*....|....
gi 488992311 427 FFAFAIFIMIFDPDTLLALLASPL 450
Cdd:PRK10197 393 FITFVLVVMLFRPAQQLEVISTGL 416
AA_permease_2 pfam13520
Amino acid permease;
32-442 1.74e-23

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 102.39  E-value: 1.74e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   32 IALGGAIGTGLFMGAGrnIAVAGTSILVIYVLVGF-FTYMVMRAMGELLLTRHDYRSFADFVGEYLGPQASFYLGWTYWL 110
Cdd:pfam13520   9 LVIGSVIGSGIFVAPL--VASGGPALIVWGWIAAIiFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAFLAGWSNWF 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  111 SWVVTCIADVVVCGSYMQYWFPE------LSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKVITIIALIgtggwmI 184
Cdd:pfam13520  87 AYVLGLASSASVAASYLLSALGPdlvpttWLTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLLLPLILI------I 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  185 ATGWTSPDGVTASLSHLTDPTaFMPHGITGFFAGFQIAIFSFTGIELLGTMTAETrdPQRILPKAINALPLRIIIFYLLS 264
Cdd:pfam13520 161 ILGLVTADGGGFNLLSGEWHT-FFPDGWPGVFAGFLGVLWSFTGFESAANVSEEV--KKRNVPKAIFIGVIIVGVLYILV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  265 MVVIIAVASWPGVSAET---SPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHAHWQFRILSR 341
Cdd:pfam13520 238 NIAFFGVVPDDEIALSSglgQVAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKV 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  342 STR-IPVRSLLFSCFCMLIGTLLLFLVPNVmtlFTIVSTLAAIMVVFSWGMILVAYLVYRRQRPDLHagsifKMPAGVVM 420
Cdd:pfam13520 318 NKFgSPIRAIILTAILSLILLLLFLLSPAA---YNALLSLSAYGYLLSYLLPIIGLLILRKKRPDLG-----RIPGRWPV 389

                         410       420
                  ....*....|....*....|..
gi 488992311  421 SWVSLLFFAFAIFIMIFDPDTL 442
Cdd:pfam13520 390 AIFGILFSLFLIVALFFPPVGP 411
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 11-464 1.01e-11

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 66.69  E-value: 1.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   11 AAGGEGASQLKRGLSARHIQMIALGGAIGTGLFM---GAGRNIAVAGTSILV-----IYVLVGFFTYM-----VMRAMGE 77
Cdd:TIGR00911  31 TVDGGEAVALKKEITLLSGVGIIVGTIIGSGIFVspkGVLKNAGSVGLALIMwavcgIFSIVGALVYAelgttIPKSGGE 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   78 LLLTRHDYRSFADFVGEYLGPQAsFYLGWTYWLSWVvtcIADVVVCGSYMQYWFPELSAWMPALSMLAILFLLNLLSVKM 157
Cdd:TIGR00911 111 YNYILEVFGPLLAFLRLWIELLV-IRPGSQAVNALN---FAIYILTPVFPDCEVPEWAIRLVAVLCVLLLTLVNCLSVKW 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  158 FGEAEFWFALIKVITIIALIGTGGWMIATGWTSPDGVTASLSHlTDPTAFmphgitGFFAGFQIAIFSFTGIELLGTMTA 237
Cdd:TIGR00911 187 ATRVQDIFTACKLLALLLIIITGWVQLGKGGVESLNPKNAFEG-TETSAG------GIVLAFYSGIWAYGGWNYLNFVTE 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  238 ETRDPQRILPKAINALPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAKAGLPAAAAVINFVALtSAMSSANSGVF 317
Cdd:TIGR00911 260 EVKNPYRTLPIAIIISMPIVTFIYVLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPALVGL-SCFGSVNGSLF 338

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  318 SSTRMLYGLSVEKHAHWQFRILSRSTRIPVRSLLFSCFcmligTLLLFLVPNvmTLFTIVSTLAAIMVVFSwGMILVAYL 397
Cdd:TIGR00911 339 SSSRLFFVGGREGHLPSLLSMIHVKRLTPLPSLLIVCT-----LTLLMLFSG--DIYSLINLISFANWLFN-ALAVAGLL 410

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488992311  398 VYRRQRPDLHAGsiFKMPAgvvmsWVSLLFFAFAIFIMIF----DPDT-----LLALLASPLWFIALWgfWKLKQR 464
Cdd:TIGR00911 411 WLRYKRPEMNRP--IKVPL-----FFPVFFLLSCLFLIILslysPPVGcgvgfIIMLTGVPVYFFGVW--WQNKPK 477
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 18-402 6.93e-10

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 61.37  E-value: 6.93e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   18 SQLKRGLSARHIQMIALGGAIGTGLFMGAGRNI-AVAGTSILVIYVLVGFFTYMVMRAMGELLLTRHDYRSFADFVGEYL 96
Cdd:TIGR00906  24 SKMKRCLTTWDLMALGIGSTIGAGIYVLTGEVArNDSGPAIVLSFLISGLAAVLSGFCYAEFGARVPKAGSAYLYSYVTV 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311   97 GPQASFYLGWTYWLSWVvtcIADVVVCGSYMQYwFPELsawmpaLSMLAILFLLNLLSVKMFGEAE----FWFALIKVIT 172
Cdd:TIGR00906 104 GELWAFITGWNLILEYV---IGTAAVARSWSAY-FDEL------LNKQIGQFRRTYFKLNYDGLAEypdfFAVCLILLLA 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  173 IIALIGTGG-----------------WMIATGWTSPDGVTASLSHLTDPTAFMPHGITGFFAGFQIAIFSFTGIELLGTM 235
Cdd:TIGR00906 174 VLLSFGVKEsawvnkiftainilvllFVIIAGFTKADVANWSITEEKGAGGFMPYGFTGVLSGAATCFFAFIGFDAIATT 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  236 TAETRDPQRILPKAINALPLRIIIFYLLSMVVIIAVASWPGVSaETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSG 315
Cdd:TIGR00906 254 GEEVKNPQRAIPIGIVTSLLVCFVAYFLMSAALTLMMPYYLLD-PDAPFPVAFEYVGWDPAKYIVAVGALCGMSTSLLGG 332

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  316 VFSSTRMLYGLSvekHAHWQFRILSR---STRIPVrsllfscfcmlIGTLLLFLVPNVMTLFTIVSTLAAIMVV---FSW 389
Cdd:TIGR00906 333 MFPLPRVIYAMA---RDGLLFKWLAQinsKTKTPI-----------NATVVSGAIAALMAFLFDLKALVDLLSIgtlLAY 398

                         410
                  ....*....|...
gi 488992311  390 GMILVAYLVYRRQ 402
Cdd:TIGR00906 399 SLVAACVLILRYQ 411
frlA PRK11357
amino acid permease;
16-426 1.02e-06

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 51.01  E-value: 1.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  16 GASQLKRGLSARHIQMIALGGAIGTGLFMGAGRNIAVAGTSILVI--YVLVGFFTYMVMRAMGELLLTRHDYRSFADFVG 93
Cdd:PRK11357   2 GSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVlaFVIGGLIVIPQMCVYAELSTAYPENGADYVYLK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311  94 EYLGPQASFYLGW-TYWLSWVVTCIADVVVCGSYMQYWFP--ELSAWMPALSMLAILFLLNLLSVKMFGEAEFWFALIKV 170
Cdd:PRK11357  82 NAGSRPLAFLSGWaSFWANDAPSLSIMALAIVSNLGFLTPidPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 171 ITIIALIGTGGWmiatgWTSPDGVTASLSHLTDPTAfmphGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAI 250
Cdd:PRK11357 162 IPFTIVIGLGIF-----WFKAENFAAPTTTAIGATG----SFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRAL 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 251 NALPLRIIIFYLLSMVVIIAVASWPGVSAETSPFVTLFAK--AGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSV 328
Cdd:PRK11357 233 IGSCLLVLVLYTLLALVISGLMPFDKLANSETPISDALTWipALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAK 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 329 EKHAHWQFRILSRSTRIPVRSLLFSCfcmLIGTLLLFL--VPNVMTLFTIVSTLAAIMVVFSWgmilvaylVYRRQRPDL 406
Cdd:PRK11357 313 DNLFFKCFGHVHPKYNTPDVSIILQG---ALGIFFIFVsdLTSLLGYFTLVMCFKNTLTFGSI--------IWCRKRDDY 381

                        410       420
                 ....*....|....*....|
gi 488992311 407 HagSIFKMPAGVVMSWVSLL 426
Cdd:PRK11357 382 K--PLWRTPAFGLMTTLAIA 399
PRK11021 PRK11021
putative transporter; Provisional
 196-366 7.57e-03

putative transporter; Provisional


Pssm-ID: 236823 [Multi-domain]  Cd Length: 410  Bit Score: 38.74  E-value: 7.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 196 ASLSHLTDPTAFMPhGITGFFAGFQIAIFSFTGIELLGTMTAETRDPQRILPKAINALPLRIIIFYLLSMVVIIAVASWP 275
Cdd:PRK11021 161 IKPADIPFPAPGSI-EWSGLFAALGVMFWCFVGIEAFAHLASEFKNPERDFPRALMIGLLLAGLVYWACTVVVLHFPAYG 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488992311 276 GVSAETSPFVTLFAKAGLPAAAAVINFVALTSAMSSANSGVFSSTRMLYGLSVEKHAHWQFRILSRStRIPVRSLLFSCF 355
Cdd:PRK11021 240 DKQAAAASLPGIFVQLFGGYALWVICVIGYLACFASVNIYTQSFARLVWSQAREGRPPSYLARLSAR-GVPVNALNAVLG 318

                        170
                 ....*....|.
gi 488992311 356 CMLIGTLLLFL 366
Cdd:PRK11021 319 CCAVSILLIYA 329
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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