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Conserved domains on  [gi|488974237|ref|WP_002885141|]
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MULTISPECIES: DUF485 domain-containing protein [Klebsiella]

Protein Classification

DUF485 domain-containing protein( domain architecture ID 10006997)

DUF485 domain-containing protein similar to Escherichia coli inner membrane protein YjcH and Bacillus subtilis rotein YwcB

Gene Ontology:  GO:0016020
TCDB:  9.B.136

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YjcH COG3162
Uncharacterized membrane protein, DUF485 family [Function unknown];
2-103 2.39e-42

Uncharacterized membrane protein, DUF485 family [Function unknown];


:

Pssm-ID: 442396  Cd Length: 104  Bit Score: 134.16  E-value: 2.39e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974237   2 NEQLCQRIENSSHFRELVASRQRFAAILSVIMLVIYVGFILLIAFAPGWLGTPLhaGTSVTRGIPLGIGVIVISFILTGI 81
Cdd:COG3162    4 PEEDYERIQASPEFQELVRRRRRFAFPLTAIFLVWYFGFILLIAFAPGFLATPV--GGVITVGIPLGLGQFVSTFVLTGI 81

                         90       100
                 ....*....|....*....|..
gi 488974237  82 YVWRANGEFDRLTKSVLNEVKA 103
Cdd:COG3162   82 YVRRANREFDPLAEEIREEVEK 103
 
Name Accession Description Interval E-value
YjcH COG3162
Uncharacterized membrane protein, DUF485 family [Function unknown];
2-103 2.39e-42

Uncharacterized membrane protein, DUF485 family [Function unknown];


Pssm-ID: 442396  Cd Length: 104  Bit Score: 134.16  E-value: 2.39e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974237   2 NEQLCQRIENSSHFRELVASRQRFAAILSVIMLVIYVGFILLIAFAPGWLGTPLhaGTSVTRGIPLGIGVIVISFILTGI 81
Cdd:COG3162    4 PEEDYERIQASPEFQELVRRRRRFAFPLTAIFLVWYFGFILLIAFAPGFLATPV--GGVITVGIPLGLGQFVSTFVLTGI 81

                         90       100
                 ....*....|....*....|..
gi 488974237  82 YVWRANGEFDRLTKSVLNEVKA 103
Cdd:COG3162   82 YVRRANREFDPLAEEIREEVEK 103
DUF485 pfam04341
Protein of unknown function, DUF485; This family represents a putative component of ActP-like ...
 10-99 6.24e-35

Protein of unknown function, DUF485; This family represents a putative component of ActP-like carboxylate transporters. Several members are cofit with adjacent ActP-like permeases, and the family appears to represent a membrane protein. It has been suggested to be involved in pyruvate utilization.


Pssm-ID: 461268  Cd Length: 89  Bit Score: 114.87  E-value: 6.24e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974237   10 ENSSHFRELVASRQRFAAILSVIMLVIYVGFILLIAFAPGWLGTPLHAGtSVTRGIPLGIGVIVISFILTGIYVWRANGE 89
Cdd:pfam04341   1 QASPKFQELVRRRRRFAWPLTAIFLVWYFGFVLLAAFAPDFLATPVGEG-VITVGIPLGLGQFVLTFLLTGIYVRRANRE 79

                          90
                  ....*....|
gi 488974237   90 FDRLTKSVLN 99
Cdd:pfam04341  80 FDPLAEEIRE 89
 
Name Accession Description Interval E-value
YjcH COG3162
Uncharacterized membrane protein, DUF485 family [Function unknown];
2-103 2.39e-42

Uncharacterized membrane protein, DUF485 family [Function unknown];


Pssm-ID: 442396  Cd Length: 104  Bit Score: 134.16  E-value: 2.39e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974237   2 NEQLCQRIENSSHFRELVASRQRFAAILSVIMLVIYVGFILLIAFAPGWLGTPLhaGTSVTRGIPLGIGVIVISFILTGI 81
Cdd:COG3162    4 PEEDYERIQASPEFQELVRRRRRFAFPLTAIFLVWYFGFILLIAFAPGFLATPV--GGVITVGIPLGLGQFVSTFVLTGI 81

                         90       100
                 ....*....|....*....|..
gi 488974237  82 YVWRANGEFDRLTKSVLNEVKA 103
Cdd:COG3162   82 YVRRANREFDPLAEEIREEVEK 103
DUF485 pfam04341
Protein of unknown function, DUF485; This family represents a putative component of ActP-like ...
 10-99 6.24e-35

Protein of unknown function, DUF485; This family represents a putative component of ActP-like carboxylate transporters. Several members are cofit with adjacent ActP-like permeases, and the family appears to represent a membrane protein. It has been suggested to be involved in pyruvate utilization.


Pssm-ID: 461268  Cd Length: 89  Bit Score: 114.87  E-value: 6.24e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488974237   10 ENSSHFRELVASRQRFAAILSVIMLVIYVGFILLIAFAPGWLGTPLHAGtSVTRGIPLGIGVIVISFILTGIYVWRANGE 89
Cdd:pfam04341   1 QASPKFQELVRRRRRFAWPLTAIFLVWYFGFVLLAAFAPDFLATPVGEG-VITVGIPLGLGQFVLTFLLTGIYVRRANRE 79

                          90
                  ....*....|
gi 488974237   90 FDRLTKSVLN 99
Cdd:pfam04341  80 FDPLAEEIRE 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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