|
Name |
Accession |
Description |
Interval |
E-value |
| uvrD |
PRK11773 |
DNA-dependent helicase II; Provisional |
1-720 |
0e+00 |
|
DNA-dependent helicase II; Provisional
Pssm-ID: 236976 [Multi-domain] Cd Length: 721 Bit Score: 1604.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 1 MDVSYLLDSLNDKQREAVAASRTNMLVLAGAGSGKTRVLVHRIAWLLSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGT 80
Cdd:PRK11773 1 MDVSYLLDSLNDKQREAVAAPLGNMLVLAGAGSGKTRVLVHRIAWLMQVENASPYSIMAVTFTNKAAAEMRHRIEQLLGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 81 TQGGMWVGTFHGLAHRLLRAHHLDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ 160
Cdd:PRK11773 81 SQGGMWVGTFHGLAHRLLRAHWQDANLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPPRQAQWYINGQKDEGLRPQHIQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 161 SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT 240
Cdd:PRK11773 161 SYGDPVEQTWLKIYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYQERFTHILVDEFQDTNAIQYAWIRLLAGDT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISL 320
Cdd:PRK11773 241 GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTANILKAANALIANNNGRLGKELWTDGGDGEPISL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 321 YCAFNDLDEARFVVNRIKTWQENGGALEQCAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIAN 400
Cdd:PRK11773 321 YCAFNELDEARFVVERIKTWQDNGGALSDCAILYRSNAQSRVLEEALLQAGIPYRIYGGMRFFERQEIKDALAYLRLIAN 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 401 RNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQASRELLKEKALAGRAASALQRFMELIDALAQETTDMPLHVQ 480
Cdd:PRK11773 401 RNDDAAFERVVNTPTRGIGDRTLDVVRQTARDRQLTLWQACRALLQEKVLAGRAASALQRFIELIDALAQETADMPLHEQ 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 481 TDRVIKDSGLRAMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLH 560
Cdd:PRK11773 481 TDRVIKDSGLRAMYEQEKGEKGQARIENLEELVTATRQFSYPDEDEDLTPLQAFLSHAALEAGEGQADAHEDAVQLMTLH 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 561 SAKGLEFPQVFIVGVEEGMFPSQMALDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPQEC 640
Cdd:PRK11773 561 SAKGLEFPLVFIVGMEEGLFPSQMSLEEGGRLEEERRLAYVGITRAMQKLTLTYAESRRLYGKEVYHRPSRFIREIPEEC 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 641 VEEVRLRATVSRPVNHQRLGAPIA-ESDTGYKLGQRVRHPKFGEGTIVNLEGSGEHSRLQVAFQGQGIKWLVAAYARLEA 719
Cdd:PRK11773 641 VEEVRLRATVSRPVSHQRMGTPAVeANDSGFKLGQRVRHPKFGEGTIVNFEGSGAHARVQVAFQGQGIKWLVAAYAKLEA 720
|
.
gi 488972480 720 V 720
Cdd:PRK11773 721 V 721
|
|
| uvrD |
TIGR01075 |
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, ... |
6-718 |
0e+00 |
|
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130147 [Multi-domain] Cd Length: 715 Bit Score: 1403.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 6 LLDSLNDKQREAVAASRTNMLVLAGAGSGKTRVLVHRIAWLLSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTTQGGM 85
Cdd:TIGR01075 1 LLDGLNDKQREAVAAPPGNLLVLAGAGSGKTRVLTHRIAWLLSVENASPHSIMAVTFTNKAAAEMRHRIGALLGTSARGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 86 WVGTFHGLAHRLLRAHHLDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNP 165
Cdd:TIGR01075 81 WIGTFHGLAHRLLRAHHLDAGLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPPRQAMWYINNQKDEGLRPSHIQAFDNP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 166 VEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVMI 245
Cdd:TIGR01075 161 VERTWIKIYQAYQEACDRAGLVDFAELLLRAHELLRNKPHILQHYQERFTHILVDEFQDTNKIQYAWIRLLAGNTGNVMI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 246 VGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFN 325
Cdd:TIGR01075 241 VGDDDQSIYGWRGAQVENIQKFLKDFPGAETIRLEQNYRSTANILAAANALIANNDERLGKNLWTDGEVGEPISLYSAFN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 326 DLDEARFVVNRIKTWQENGGALEQCAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDA 405
Cdd:TIGR01075 321 ELDEARFVVSRIKTWQRNGGALDECAVLYRSNAQSRVLEEALLQASIPYRIYGGMRFFERQEIKDALAYLRLIANRNDDA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 406 AFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQASRELLKEKALAGRAASALQRFMELIDALAQETTDMPLHVQTDRVI 485
Cdd:TIGR01075 401 AFERVINTPTRGIGDRTLDVVRQAARDRGLTLWQAARELTQEKVLAGRAASALQRFVELIEALANETADMPLHVQTDHVI 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 486 KDSGLRAMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGL 565
Cdd:TIGR01075 481 KDSGLREMYQQEKGEKGQARIENLEELVTATRQFSLPENDEDMTPLTAFLSHAALEAGEGQADAGQDAVQLMTLHSAKGL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 566 EFPQVFIVGVEEGMFPSQMALDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPQECVEEVR 645
Cdd:TIGR01075 561 EFPLVFLVGMEEGMFPSQMSLDEGGRLEEERRLAYVGITRAMQKLTITYAETRRLYGKEVYHIPSRFIRELPEECLHEVR 640
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488972480 646 LRATVSRPVNHQRLGAPIAES--DTGYKLGQRVRHPKFGEGTIVNLEGSGEHSRLQVAFQGQGIKWLVAAYARLE 718
Cdd:TIGR01075 641 LRAQVSRPTNLGRVGTPSVDEinDAGFKLGQRVRHPKFGEGTIINAEGSGEHSRLQIAFQGQGIKWLVAAYAKLE 715
|
|
| UvrD |
COG0210 |
Superfamily I DNA or RNA helicase [Replication, recombination and repair]; |
6-720 |
0e+00 |
|
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain] Cd Length: 721 Bit Score: 968.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 6 LLDSLNDKQREAVAASRTNMLVLAGAGSGKTRVLVHRIAWLLSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTTQGGM 85
Cdd:COG0210 3 LLAGLNPEQRAAVEHPEGPLLVLAGAGSGKTRVLTHRIAYLIAEGGVDPEQILAVTFTNKAAREMRERIEALLGRLARGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 86 WVGTFHGLAHRLLRAHHLDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSY--G 163
Cdd:COG0210 83 WVGTFHSLALRILRRHAELLGLPPNFTILDGDDQLRLIKELLKELGLDEKRFPPRELLSLISRAKNEGLTPEELAELlaA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 164 NPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKV 243
Cdd:COG0210 163 DPEWRAAAELYEAYQERLRANNALDFDDLLLLAVRLLEENPEVLEKYQNRFRYILVDEYQDTNPAQYELLRLLAGDGRNL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 244 MIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCA 323
Cdd:COG0210 243 CVVGDDDQSIYGFRGADPENILRFEKDFPDAKVIKLEQNYRSTQNILDAANAVIANNPGRLGKNLWTDNGEGEKVRLYVA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 324 FNDLDEARFVVNRIKTWQENGGALEQCAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRND 403
Cdd:COG0210 323 PDEEEEARFVADEIRELHEEGVPLSDIAVLYRTNAQSRALEEALRRAGIPYRVVGGLRFYERAEIKDLLAYLRLLANPDD 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 404 DAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQASRELLKEKALAGRAASALQRFMELIDALAQETTDMPLHVQTDR 483
Cdd:COG0210 403 DVALLRILNVPRRGIGAATLERLREAAREEGISLLEALRDLGELAGLSGRAAKALRRFAELLEALRAAAERLPLEELLEA 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 484 VIKDSGLRAMYEQEKGEKGQTRIENLEELVTATRQFsynEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAK 563
Cdd:COG0210 483 LLDESGYEEELREEAGEEAERRLENLEELVDAAARF---EERNPGASLEAFLEELALLSDLDAADEDEDAVTLMTLHAAK 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 564 GLEFPQVFIVGVEEGMFPSQMALDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPQECVEE 643
Cdd:COG0210 560 GLEFPVVFLVGLEEGLFPHQRSLDDEEELEEERRLFYVAITRARERLYLTYAASRRLWGETQDNEPSRFLDELPEELLEW 639
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488972480 644 VRLRATVSRPVNHQRLGAPIAESDTGYKLGQRVRHPKFGEGTIVNLEGSGEHSRLQVAFQGQGIKWLVAAYARLEAV 720
Cdd:COG0210 640 VRPKAEAAAAAASAAAALPASGAGAAALAAGAAAAAAAAGGGAAVAGAGLGRAAAAGGADGGAAGAGGGLAAVALTV 716
|
|
| pcrA |
TIGR01073 |
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. ... |
6-718 |
0e+00 |
|
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273429 [Multi-domain] Cd Length: 726 Bit Score: 780.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 6 LLDSLNDKQREAVAASRTNMLVLAGAGSGKTRVLVHRIAWLLSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTTQGGM 85
Cdd:TIGR01073 1 LLAHLNPEQREAVKTTEGPLLIMAGAGSGKTRVLTHRIAHLIAEKNVAPWNILAITFTNKAAREMKERVEKLLGPVAEDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 86 WVGTFHGLAHRLLRAHHLDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ-SYGN 164
Cdd:TIGR01073 81 WISTFHSMCVRILRRDIDRIGINRNFSIIDPTDQLSLMKTILKDKNLDPKKFEPRSILGTISNAKNELLPPEDFAkEATN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 165 PVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVM 244
Cdd:TIGR01073 161 YFEKVVAEVYQEYQKRLLRNNALDFDDLIMTTINLFQRVPDVLEYYQRKFQYIHVDEYQDTNRAQYTLVRLLASRFRNLC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 245 IVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAF 324
Cdd:TIGR01073 241 VVGDADQSIYGWRGADIQNILSFEKDYPNATTILLEQNYRSTKNILQAANEVIEHNSNRKPKNLWTENSSGDKITYYEAD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 325 NDLDEARFVVNRIKTWQENG-GALEQCAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRND 403
Cdd:TIGR01073 321 TERDEAQFVAGEIDKLVKNGeRKYGDFAILYRTNAQSRVFEETLLKANIPYKIVGGLKFYDRKEIKDILAYLRVIANPDD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 404 DAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQASRELLKEKALAGRAASALQRFMELIDALAQETTDMPLHVQTDR 483
Cdd:TIGR01073 401 DLSLLRIINVPKRGIGASSLEKIVNYALELNISLFEAIGEIDEIGGLAAKSANALLAFATMIENLRQQQEYLSPTELVEE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 484 VIKDSGLRAMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEdlmPLQAFLSHAALEAGEGQADTWQ--DAVQLMTLHS 561
Cdd:TIGR01073 481 VLDKSGYREMLKAEKTEEAQSRLENLDEFLSVTKEFEDESEDK---SLIDFLTDLALVSDLDELEETEegGAVTLMTLHA 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 562 AKGLEFPQVFIVGVEEGMFPSQMALDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPQECV 641
Cdd:TIGR01073 558 AKGLEFPVVFLIGMEEGVFPHSRSLMDEKELEEERRLAYVGITRAEEELYLTHATMRTLFGRIQMNPPSRFLNEIPAELL 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 642 EEVR---------------LRATVSRPVNHQrlgaPIAESDTG-YKLGQRVRHPKFGEGTIVNLEGSGEHSRLQVAFQGQ 705
Cdd:TIGR01073 638 ETAStgrrtgatdpkgpsiRQAGASRPTTSQ----PTAGGDTLsWAVGDRVNHKKWGIGTVVSVKGGGDDQELDIAFPSI 713
|
730
....*....|...
gi 488972480 706 GIKWLVAAYARLE 718
Cdd:TIGR01073 714 GVKRLLAAFAPIE 726
|
|
| rep |
TIGR01074 |
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. ... |
9-664 |
0e+00 |
|
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130146 [Multi-domain] Cd Length: 664 Bit Score: 565.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 9 SLNDKQREAVAASRTNMLVLAGAGSGKTRVLVHRIAWLlsVENC--SPYSIMAVTFTNKAAAEMRHRIGQLMGTTQG-GM 85
Cdd:TIGR01074 1 KLNPQQQEAVEYVTGPCLVLAGAGSGKTRVITNKIAYL--IQNCgyKARNIAAVTFTNKAAREMKERVAKTLGKGEArGL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 86 WVGTFHGLAHRLLRAHHLDANLPQDFQILDSEDQLRLLKRLIKAMnLDEKQWPPRQAMWYINSQKDEGLRPHHI-QSYGN 164
Cdd:TIGR01074 79 TISTFHTLGLDIIKREYNALGYKSNFSLFDETDQLALLKELTEGL-IKDDKDLLDKLISTISNWKNDLLTPEQAlASARG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 165 PVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVM 244
Cdd:TIGR01074 158 EREQTFAHCYALYQAHLRAYNALDFDDLILLPTLLLQQNEEVRNRWQNKIRYLLVDEYQDTNTSQYELVKLLVGDRARFT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 245 IVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAF 324
Cdd:TIGR01074 238 VVGDDDQSIYSWRGARPENLVLLKEDFPQLKVIKLEQNYRSTGRILKAANILIANNPHVFEKKLFSELGYGEKIKVIECN 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 325 NDLDEARFVVNRIKTWQENGGA-LEQCAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRND 403
Cdd:TIGR01074 318 NEEHEAERIAGEIIAHKLVNKTqYKDYAILYRGNHQSRLLEKALMQNRIPYKLSGGTSFFSRPEIKDLLSYLRLLVNPDD 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 404 DAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQASRELLKEKALAGRAASALQRFMELIDALAQETTDMPLHVQTDR 483
Cdd:TIGR01074 398 DAAFLRIVNTPKREIGPATLEKLGELAMERNKSLFTASFDMGLLQTLSGRGYESLQRFTDWLVEIRRLAERSEPIEAVRS 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 484 VIKDSGLRA-MYEQEKGEKG-QTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAAL----EAGEGQADTwqDAVQLM 557
Cdd:TIGR01074 478 LIEDIDYENwLYETSPSPKAaEMRMKNVNTLFSWFKEMLEGDEEDEPMTLTQVVTRLTLrdmlERGEDEEEL--DQVQLM 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 558 TLHSAKGLEFPQVFIVGVEEGMFPSQMALDEgGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELP 637
Cdd:TIGR01074 556 TLHASKGLEFPYVFIVGMEEGILPHQSSIEE-DNVEEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLDELP 634
|
650 660
....*....|....*....|....*..
gi 488972480 638 QECVEEVRLRATVSRPVNHQRLGAPIA 664
Cdd:TIGR01074 635 QEDLQWEGDDPVVSAEEKMEKGQAHLA 661
|
|
| PRK10919 |
PRK10919 |
ATP-dependent DNA helicase Rep; Provisional |
10-651 |
3.52e-149 |
|
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain] Cd Length: 672 Bit Score: 450.06 E-value: 3.52e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 10 LNDKQREAVAASRTNMLVLAGAGSGKTRVLVHRIAWLLSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTTQG-GMWVG 88
Cdd:PRK10919 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVAQTLGRKEArGLMIS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 89 TFHGLAHRLLRAHHLDANLPQDFQILDSEDQLRLLKRLIKAMnLDEKQWPPRQAMWYINSQKDEGLRPHH-IQSYGNPVE 167
Cdd:PRK10919 83 TFHTLGLDIIKREYAALGMKSNFSLFDDTDQLALLKELTEGL-IEDDKVLLQQLISTISNWKNDLKTPAQaAAGAKGERD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 168 QTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVMIVG 247
Cdd:PRK10919 162 RIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 248 DDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNDL 327
Cdd:PRK10919 242 DDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVLSANNEE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 328 DEARFVVNR-IKTWQENGGALEQCAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAA 406
Cdd:PRK10919 322 HEAERVTGElIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 407 FERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQASRELLKEKALAGRAASALQRFMELIDALAQETTDMPLHVQTDRVIK 486
Cdd:PRK10919 402 FLRIVNTPKREIGPATLQKLGEWAMTRNKSLFTASFDMGLSQTLSGRGYESLTRFTHWLAEIQRLAEREPVAAVRDLIHG 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 487 DSGLRAMYEQEKGEK-GQTRIENLEELVT-ATRQFSYNEEDEDLMPLQA---FLSHAALEAGEGQADTwqDAVQLMTLHS 561
Cdd:PRK10919 482 IDYESWLYETSPSPKaAEMRMKNVNQLFSwMTEMLEGSELDEPMTLTQVvtrFTLRDMMERGESEEEL--DQVQLMTLHA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 562 AKGLEFPQVFIVGVEEGMFPSQMALDEGGrLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPQECV 641
Cdd:PRK10919 560 SKGLEFPYVYLVGMEEGLLPHQSSIDEDN-IDEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELPQDDL 638
|
650
....*....|
gi 488972480 642 EEVRLRATVS 651
Cdd:PRK10919 639 IWEQERKVVS 648
|
|
| UvrD-helicase |
pfam00580 |
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural ... |
10-272 |
1.13e-118 |
|
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Swiss:P23478, Swiss:P08394 have large insertions near to the carboxy-terminus relative to other members of the family.
Pssm-ID: 395462 [Multi-domain] Cd Length: 267 Bit Score: 356.56 E-value: 1.13e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 10 LNDKQREAVAASRTNMLVLAGAGSGKTRVLVHRIAWLLSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTTQ-GGMWVG 88
Cdd:pfam00580 1 LNPEQRKAVTHLGGPLLVLAGAGSGKTRVLTERIAYLILEGGIDPEEILAVTFTNKAAREMKERILKLLGKAElSELNIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 89 TFHGLAHRLLRAHHLDANLPQDFQILDSEDQLRLLKRLIKA--MNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSY-GNP 165
Cdd:pfam00580 81 TFHSFCLRILRKYANRIGLLPNFSILDELDQLALLKELLEKdrLNLDPKLLRKLELKELISKAKNRLLSPEELQQGaADP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 166 VEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVMI 245
Cdd:pfam00580 161 RDKLAAEFYQEYQERLKENNALDFDDLLLLTLELLRSDPELLEAYRERFKYILVDEFQDTNPIQYRLLKLLAGGHENLFL 240
|
250 260
....*....|....*....|....*..
gi 488972480 246 VGDDDQSIYGWRGAQVENIQRFLNDFP 272
Cdd:pfam00580 241 VGDPDQSIYGFRGADIENILKFEKDFP 267
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
9-619 |
3.53e-103 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 335.39 E-value: 3.53e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 9 SLNDKQREAVAASRTNMLVLAGAGSGKTRVLVHRIAWLLSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMG--------- 79
Cdd:COG1074 5 PWTDAQRRALDPLGGSVLVEASAGSGKTYTLVARYLRLLLERGLDPEEILVVTFTRAAAAEMRERIRERLAeaadledpd 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 80 ---------------TTQGGMWVGTFHGLAHRLLRAHHLDANLPQDFQILDSEDQL------------------------ 120
Cdd:COG1074 85 leelararrrlaralENLDRAAISTIHSFCQRLLREFAFEAGLDPNFELLDDAEALlleeavddllreayapldalalar 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 121 -------------RLLKRLIKAMNldEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQK--------------V 173
Cdd:COG1074 165 lldafgrdddsleELLLALYKLRS--RPDWLEELAELDEALEALREALLKAKEALAALREALAAAaapllaallrllaaV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 174 YQAYQEACDRAGLVDFAELLLRAHELwLNKPH---ILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGD----TGKVMIV 246
Cdd:COG1074 243 LARYERRKRERGLLDFDDLLHRALRL-LRDEDapwVAERLRERYRHILVDEFQDTSPLQWEILRRLAGEaladGRTLFLV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 247 GDDDQSIYGWRGAQVENIQRFLNDFPG---AETIRLEQNYRSTSNILSAANALIENNNG--------------RLGK--- 306
Cdd:COG1074 322 GDPKQSIYRFRGADPELFLEARRALEGrvdGERLTLTTNFRSTPEVVDAVNALFAQLMGagfgeipyepvealRPGAypa 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 307 -KLWTDGADGEPISLYcafnDLDEARFVVNRIKTWQENGGALEQC---------AILYRSNAQSRVLEEALLQASMPYRI 376
Cdd:COG1074 402 vELWPLEPDDVSEEDA----REREARAVAARIRRLLAEGTTVEGGgrpvrpgdiAVLVRTRSEAAAIARALKAAGIPVAA 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 377 YGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQtsRDRQLTLWQAsrellkekaLagRAAS 456
Cdd:COG1074 478 SDRLSLFESPEVRDLLALLRALLNPEDDLALAAVLRSPLFGLSDEDLAALAA--DRKGESLWEA---------L--RAYE 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 457 ALQRFMELIDALAQETTDMPLHVQTDRVIKDSGLRAMY-EQEKGEKGQTRIENLEELVTATRQFSyNEEDEDLMPLQAFL 535
Cdd:COG1074 545 RLARALERLRALRELARRLGLAELLERLLEETGLLERLlALPGGERRLANLLHLDELLQLALEYE-QTGGPGLAGFLRWL 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 536 SHAALEAGEGQA---DTWQDAVQLMTLHSAKGLEFPQVFIVGVEEgmfpsqMALDEggRLEEERRLAYVGVTRAMQKLTL 612
Cdd:COG1074 624 ERLIEDGGDEEKrrlESDADAVRIMTIHKSKGLEFPVVFLPALRE------RARAE--ELAEELRLLYVALTRARDRLVL 695
|
....*..
gi 488972480 613 TYAETRR 619
Cdd:COG1074 696 SGAVKKK 702
|
|
| UvrD_C |
pfam13361 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
277-617 |
6.33e-91 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain] Cd Length: 377 Bit Score: 288.92 E-value: 6.33e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 277 IRLEQNYRSTSNILSAANALIENNNGR----LGKKLWTDGADGEPISLYCAFNDLDEARFVVNRIKTWQENGGALEQCAI 352
Cdd:pfam13361 1 IHLEINYRSTKNLLKAANEFINNNFGRatiyPKKILAETVEDGEKIKIIEAETEEEEAEWIALEIKKLVARDEKYNDIAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 353 LYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSR- 431
Cdd:pfam13361 81 LTRSNSDADLIEEALKKLGIPYFVVGQTKFFRREEIKDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERIREYKKr 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 432 -----DRQLTLWQASRELLKEKALAGR---------------------AASALQRFMELIDALAqettdmpLHVQTDRVI 485
Cdd:pfam13361 161 glrlsDFINPDTLTYGDPFVIALEQDNivvfdvettgldttedeiiqiAAIKLNKKGVVIESFE-------RFLRLKKPV 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 486 KDS----GLRAMYEQEKGEKGQT-------RIENLEELVTATRQFSYNEEDEDLM-PLQAFLSHAALEAGEGQADTWQDA 553
Cdd:pfam13361 234 GDSlqvhGFSDEFLQENGETPAEalrdfleKLENLRELYSILREYDDIEETPEPEdALRNFLEIATLSNSELEGSDIKER 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488972480 554 VQLMTLHSAKGLEFPQVFIVGVEEGMFPSQMALDEGGRLEEERRLAYVGVTRAMQKLTLTYAET 617
Cdd:pfam13361 314 IPIMTIHQAKGLEFDTVFLAGLEEGIFPSYRSIKDEGNLEEERRLFYVAITRAKKRLYISYSKS 377
|
|
| DEXQc_UvrD |
cd17932 |
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch ... |
11-283 |
1.85e-86 |
|
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. UvrD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350690 [Multi-domain] Cd Length: 189 Bit Score: 270.16 E-value: 1.85e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 11 NDKQREAVAASRTNMLVLAGAGSGKTRVLVHRIAWLLSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTTQ-GGMWVGT 89
Cdd:cd17932 1 NPEQREAVTHPDGPLLVLAGAGSGKTRVLTHRIAYLILEGGVPPERILAVTFTNKAAKEMRERLRKLLGEQLaSGVWIGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 90 FHGLAHRLLRAHHldanlpqdfqildsedqlrllkrlikamnldekqwpprqamwyinsqkdeglrphhiqsygnpveqt 169
Cdd:cd17932 81 FHSFALRILRRYG------------------------------------------------------------------- 93
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 170 wqkvyqayqeacdraglvDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVMIVGDD 249
Cdd:cd17932 94 ------------------DFDDLLLYALELLEENPDVREKLQSRFRYILVDEYQDTNPLQYELLKLLAGDGKNLFVVGDD 155
|
250 260 270
....*....|....*....|....*....|....
gi 488972480 250 DQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNY 283
Cdd:cd17932 156 DQSIYGFRGADPENILDFEKDFPDAKVIKLEENY 189
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
285-614 |
1.85e-34 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 128.50 E-value: 1.85e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 285 STSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNDLDEARFVVNRIKTWQENGG-ALEQCAILYRSNAQSRVL 363
Cdd:cd18807 1 STKNILDAANSLIKQNKNRPKKPLKAGNKSGGPVELLLAKDEADEAKAIADEIKRLIESGPvQYSDIAILVRTNRQARVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 364 EEALLqasmpyriyggmrfferqeikdalsylrlianrnddaafervvntptrgigdrtldvvrqtsrdrqltlwqasre 443
Cdd:cd18807 81 EEALR--------------------------------------------------------------------------- 85
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 444 llkekalagraasalqrfmelidalaqettdmplhvqtdrvikdsglramyeqekgekgqtrienleelvtatrqfsyne 523
Cdd:cd18807 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 524 ededlmplqaflshaaleagegqadtwqdaVQLMTLHSAKGLEFPQVFIVGVEEGMFPSQMA----LDEGGRLEEERRLA 599
Cdd:cd18807 86 ------------------------------VTLMTIHASKGLEFPVVFIVGLGEGFIPSDASyhaaKEDEERLEEERRLL 135
|
330
....*....|....*
gi 488972480 600 YVGVTRAMQKLTLTY 614
Cdd:cd18807 136 YVALTRAKKELYLVG 150
|
|
| addA_Gpos |
TIGR02785 |
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, ... |
12-612 |
6.89e-34 |
|
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274299 [Multi-domain] Cd Length: 1230 Bit Score: 139.84 E-value: 6.89e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 12 DKQREAVAASRTNMLVLAGAGSGKTRVLVHRI-AWLLSVENCSpySIMAVTFTNKAAAEMRHRIGQ-------------- 76
Cdd:TIGR02785 4 DEQWQAIYTRGQDILVSASAGSGKTAVLVERIiRKITRGVDVD--RLLVVTFTNAAAREMKERIAEalekelvqepnskh 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 77 ------LMGTTQggmwVGTFHGLAHRLLRAHHLDANLPQDFQILDSEDQLRLLK-------------------------- 124
Cdd:TIGR02785 82 lrrqlaLLNTAN----ISTLHSFCLKVIRKHYYLLDLDPSFRILTDTEQLLLIKevlddvfeeeyykedkeaffelvdnf 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 125 ----------RLIKAM---------------NL------------DEKQW------------------------------ 137
Cdd:TIGR02785 158 sgdrsddglrDLILQLydfsrstpnpekwlnNLaeayevkekftiESLKLqqqikellkneleglqeklqralelfmaed 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 138 ---PPRQAMWYINSQKDEGLRPHHIQSYGNPV------------------------------------------------ 166
Cdd:TIGR02785 238 glaPRLENFQLDLQNIDELIQESLAQADWNELrkavaafkfknlkaakgdeedadlleeadklreeakkqleklktdyft 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 167 --EQTWQKVYQ------------------AYQEACDRAGLVDFAELLLRAHELWLNKPH----ILQHYRERFTNILVDEF 222
Cdd:TIGR02785 318 rsEEDHLRIMQemkpvvktlvqlvkdfieRFGAEKREKNILDFSDLEHYALQILTNENEspseAAEFYREKFHEVLVDEY 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 223 QDTNNIQYAWIRLLAGD---TGKVMIVGDDDQSIYGWRGAQ----VENIQRFLNDFPGA-ETIRLEQNYRSTSNILSAAN 294
Cdd:TIGR02785 398 QDTNLVQESILQLVKRGpeeEGNLFMVGDVKQSIYRFRQADpllfLEKYHRFAQEGEEHgKRIDLAENFRSRAEVLDTTN 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 295 -------------------------------ALIENNNGRLGKKLWTDGADGEPISLYCAFNDLD--EARFVVNRIK--- 338
Cdd:TIGR02785 478 flfkqlmdeevgeidydeeaqlkfgaakypeNPDNKTEELLYEKLLIEEAEEEEIDEEAEILDKAqqEATMVAERIKali 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 339 ----------TWQENGGALEQCAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFE 408
Cdd:TIGR02785 558 kegfkvydkkTGTYRPVTYRDIVILTRSRGWNLQIMEEFKKYGIPVFANDAENYFQTTEVRVMLSLLRVIDNPYQDIPLV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 409 RVVNTPTRGIGDRTLDVVRQTSRDRqlTLWQASRELLKEKALAGRAASALQRFMELIDALAQETTDMPLHVQTDRVIKDS 488
Cdd:TIGR02785 638 AVLRSPIVGFDENELALIRLENKDS--SYYEAVKDYVKAGLIEDELYEKLNTFLDSLQKWREFARTHSVSELIWKIYNDT 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 489 GLramYEQEKG-EKGQTRIENLEELVTATRQFSYN----------------EEDEDLmplqaflshaALEAGEGQADtwq 551
Cdd:TIGR02785 716 GY---YDYVGGlPGGKQRQANLYALYERARQYESTsfkglfqfirfiermqERQKDL----------ASAVAVGEAE--- 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 552 DAVQLMTLHSAKGLEFPQVFIVGV-----------------------------EEGMFPS--QMALDEGGRLE---EERR 597
Cdd:TIGR02785 780 NAVRLMTIHKSKGLEFPVVFVLGMgkqfnkqdlnssylldrqlglgikyidpqERLSYPSlpKVAIKQKMKREllsEEMR 859
|
890
....*....|....*
gi 488972480 598 LAYVGVTRAMQKLTL 612
Cdd:TIGR02785 860 VLYVALTRAKEKLIL 874
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
24-283 |
1.60e-28 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 110.27 E-value: 1.60e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 24 NMLVLAGAGSGKTRVLVHRIAWLLSVENCSPYSIMAVTFTNKAAAEMRhrigqlmgttqggmwvgtfhglahrllrahhl 103
Cdd:cd17914 1 LSLIQGPPGTGKTRVLVKIVAALMQNKNGEPGRILLVTPTNKAAAQLD-------------------------------- 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 104 danlpqdfqildsedqlrllkrlikamnldekqwpprqamwyinsqkdeglrphhiqsygnpveqtwqkvyqayqeacdr 183
Cdd:cd17914 --------------------------------------------------------------------------------
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 184 aglvdfaelllrahelwlnkphilqhyrerftNILVDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVEN 263
Cdd:cd17914 49 --------------------------------NILVDEAAQILEPETSRLIDLALDQGRVILVGDHDQLGPVWRGAVLAK 96
|
250 260
....*....|....*....|....*
gi 488972480 264 -----IQRFLNDFPGAETIRLEQNY 283
Cdd:cd17914 97 icneqSLFTRLVRLGVSLIRLQVQY 121
|
|
| addA_alphas |
TIGR02784 |
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, ... |
14-628 |
4.40e-26 |
|
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274298 [Multi-domain] Cd Length: 1135 Bit Score: 114.78 E-value: 4.40e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 14 QREAVAAS-RTNMLVLAGAGSGKTRVLVHRIAWLLsVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGT------------ 80
Cdd:TIGR02784 1 ARQAQAADpAASAWVSANAGSGKTHVLTQRVIRLL-LAGTEPSKILCLTYTKAAAAEMQNRVFKRLGEwavlddadlrar 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 81 --------------------------TQGGMWVGTFHGLAHRLLRAHHLDANLPQDFQILDSEDQLRLLK---------- 124
Cdd:TIGR02784 80 lealegkrpdaaklaearrlfaraleTPGGLKIQTIHAFCEALLHQFPLEANVAGHFSVIDDRAAATLLEearrallagp 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 125 ---------------------------------------------------RLIKAMNLD---------EKQWP------ 138
Cdd:TIGR02784 160 aapddaladalatvleaagetgleallaeivarrdalmafldeaggegaeaRLRRALGLApgdtaedllEAVWPlpglpr 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 139 ------PRQAMWYINSQ------------KDEGLRPHHIQSY--------GNPVEQTW------QKVYQAYQEACDRA-- 184
Cdd:TIGR02784 240 lalaliAALLKSGGGSKdaaaalsqlreaAAEPDPVARLDLLlgafltskGEPKSASFvikkaiQKSLPDLAEALEDAas 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 185 ---------------------------------------GLVDFAELLLRAHELwLNKPHILQ--HYR-ERFTN-ILVDE 221
Cdd:TIGR02784 320 rvealrerlralrmaqrtlaalrlaarllqryarlkkarGLLDFNDLIERTVAL-LARPGAGAwvHYKlDRGIDhILVDE 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 222 FQDTNNIQYAWIRLLA-----GDTGK------VMIVGDDDQSIYGWRGAQVENIQR----FLNDFPGAET----IRLEQN 282
Cdd:TIGR02784 399 AQDTSPEQWDIIQALAeeffsGEGARsgvertIFAVGDEKQSIYSFQGADPERFAEerreFSRKVRAVGRkfedLSLNYS 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 283 YRSTSNILSAANALIENNNGRLG----------------------------------KKLWTDGADGEPISlyCAFNDLd 328
Cdd:TIGR02784 479 FRSTPDVLAAVDLVFADPENARGlsadsdapvheafrddlpgrvdlwdliskeegeePEDWTDPVDELGER--APEVRL- 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 329 eARFVVNRIKTWQENGGALE---------QCAILYRS-----NAQSRvleeALLQASMPyrIYGGMRFFERQEI--KDAL 392
Cdd:TIGR02784 556 -AERIAAEIRAWLDRGTPIPgrgravrpgDILVLVRKrdaffSALIR----ALKRRGIP--VAGADRLKLTSHIavKDLM 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 393 SYLRLIANRNDDAAFERVVNTPTRGIGDRtlDVVRQTSRDRQLTLWQASRellkekalagRAASALQRFMELIDALAQET 472
Cdd:TIGR02784 629 ALGRFVLQPEDDLSLAALLKSPLFGLDED--DLFRLAAGRSGGSLWAALR----------RREAEFAATLAVLRDWLSLA 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 473 TDMPLHVQTDRVI-KDSGLRAMYEQEKGEKGqtriENLEELVTatrqFSYNEEDEDLMPLQAFLShaALEAGE----GQA 547
Cdd:TIGR02784 697 DFLTPFEFYARLLgRDGGRRKLLARLGAEAE----DILDEFLS----QALAYERTGLPGLQAFLS--WLEADDpeikREM 766
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 548 DTWQDAVQLMTLHSAKGLEFPQVFIVGVEEGMFPSQMALD---EGGR-----------------------------LEEE 595
Cdd:TIGR02784 767 DQARDEVRVMTVHGAKGLEAPVVFLVDTGSKPFASQRAPLllaTGGSggkaplwrpasafdpslsaaarerlkeraEDEY 846
|
890 900 910
....*....|....*....|....*....|...
gi 488972480 596 RRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHR 628
Cdd:TIGR02784 847 RRLLYVAMTRAEDRLIVCGYRGKRESPKDSWHA 879
|
|
| recB |
TIGR00609 |
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with ... |
26-617 |
3.40e-25 |
|
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with potent ATP-dependent exodeoxyribonuclease activity. Ejection of RecD, as occurs at chi recombinational hotspots, cripples exonuclease activity in favor of recombinagenic helicase activity. All proteins in this family for which functions are known are DNA-DNA helicases that are used as part of an exonuclease-helicase complex (made up of RecBCD homologs) that function to generate substrates for the initiation of recombination and recombinational repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273172 [Multi-domain] Cd Length: 1087 Bit Score: 112.14 E-value: 3.40e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 26 LVLAGAGSGKT--------RVLVHriAWLLSVENcspysIMAVTFTNKAAAEMRHRI----GQLMGTTQG---------- 83
Cdd:TIGR00609 13 LIEASAGTGKTftiaqlylRLLLE--GGPLTVEE-----ILVVTFTNAATEELKTRIrgriHQALRALKAaltsqelpep 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 84 -------------------------GMWVGTFHGLAHRLLRAHHLDANLPQDFQILDSEDQLRL---------------- 122
Cdd:TIGR00609 86 lkeaiqdekvkqaitrlrnalatmdEAAIYTIHGFCQRMLEQHAFESDEIFDVELIEDESLLLAeitkdfwrrnfynlpf 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 123 ------LKRLIKAMNL-----------DEKQWPPRQA------MWYINSQKDEGLRPHHI--------------QSYGNP 165
Cdd:TIGR00609 166 diaqivLKTKKSPQAVltqiladlllqSYLAFPSPPLdleqliKWHEQIYKDLDKLDHAVfeeidklnaernnlFCLKDR 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 166 VEQTWQK-VYQAYQEACDRAGLVDFAELLLRAHELwLNKPH---ILQHYRERFTNILVDEFQDTNNIQYAWIRLL--AGD 239
Cdd:TIGR00609 246 VFLTLLKeVQEELKKEKKRRREIGFDDLLSRLETA-LKSAEgekLAQAIREQYPIALIDEFQDTDPQQYRIFSKLfiAQK 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 240 TGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETirLEQNYRSTSNILSAANALIENN---------------NGRL 304
Cdd:TIGR00609 325 ETSLFLIGDPKQAIYSFRGADIFTYLQAKSKADARYT--LGTNWRSTPALVGSLNKLFSLIsnpflekpifipvlaHQKN 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 305 GK-KLWTDGADGEPISlycaFNDLDEARFVVNRIKTWQENGGALE-----QCAILYRSNAQSRVLEEALLQASMPYRIYG 378
Cdd:TIGR00609 403 SKgSFVINGQEQPPIH----FFTTEVESEGVDDYRQTIAQKCAREialwlASAALGLANFIATFGGRPLRAGDIAVLVRG 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 379 gmrffeRQE---IKDALSYLRLIAN--RNDDAAFE-----------RVVNTPTRgigDRTLDVVrQTSRDRQLTlWQASR 442
Cdd:TIGR00609 479 ------RKEanqIRKALKKAQIPSVylSDKSSVFAteeaqellallEALLEPEN---EGTLRAA-LASSIFGLS-ALELE 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 443 ELLKEKALAGRAASALQRFMELIDALAQETTDMplhvqtdRVIKDSGL-RAMYEQEKGEKGQTRIENLEELVTATRQFSY 521
Cdd:TIGR00609 548 TLNQDEITWERVVEKFREYHDIWRKIGVLAMFQ-------RLMLEKGIgERLLSQPGGERILTNLLHLAELLQEAAHQER 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 522 NEededLMPLQAFLSHAALE-AGEGQA---DTWQDAVQLMTLHSAKGLEFPQVFIVGVEEGMFPSQMALD---------- 587
Cdd:TIGR00609 621 NK----LSLLRWLEDQISNEeEEEEEIirlESDAELVKIVTIHKSKGLEYPIVFLPFITDAKKSNFASLHdqhsheyqly 696
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 488972480 588 ------------EGGRLEEERRLAYVGVTRAMQKLTLTYAET 617
Cdd:TIGR00609 697 dfnqseenqklaRVERLAEDLRLLYVALTRAKKQLFIGIAPL 738
|
|
| AddB |
COG3857 |
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair]; |
26-639 |
3.57e-25 |
|
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain] Cd Length: 1019 Bit Score: 111.76 E-value: 3.57e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 26 LVLAGAGSGKTRVLVHRIAwllsvENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTtqGGMW---VGTFHGLAHRLLRAHH 102
Cdd:COG3857 2 FILGRAGSGKTTYLLEEIK-----EELKEGKPIILLVPEQMTFQAERALLKRLGL--GGSIraqVLSFSRLAWRVLQETG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 103 LDAnlpqdFQILDSEDQLRLLKRLIKAmNLDEKQWPPRQAMWY-----INSQ----KDEGLRPHHIQSYGNPVEQTWQ-- 171
Cdd:COG3857 75 GAT-----RPLLSDAGKRMLLRKILEE-HKDELKVFARAADKPgfieqLAELitelKRYGITPEDLEEAAELLKEKLRdl 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 172 -KVYQAYQEACdRAGLVDFAELLLRAHElWLNKPHILQHyrerfTNILVDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDD 250
Cdd:COG3857 149 aLIYEAYEEKL-AGRYIDSEDLLRLLAE-KLEKSEFLEG-----AEIYIDGFTDFTPQELELLEALLKKAKEVTITLTLD 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 251 QSIYGWRGAQVENIQRFLNDfpgAETIRLEQNYRSTSNIlsaanALIENNNGRLGKKlwtdgADGEPISLYCAFNDLDEA 330
Cdd:COG3857 222 PDELDLFSATGETYERLLEL---AKENGVEVEFKKSPEL-----AHLERNLFAYPPE-----EEPEGIEIIEAANRRAEV 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 331 RFVVNRIKTW-QENGGALEQCAILYRS-NAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFE 408
Cdd:COG3857 289 EAVAREIRRLvREEGYRYRDIAVVVRDlEAYAPLIERVFAEYGIPYFIDEKRPLSHHPLVELILSLLELVRSNFRYEDVF 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 409 RVVNTP-----TRGIGDRTLDVVR----------QTSRDRQLTLWQASRELLKE-KALAGRAASALQRFM---------- 462
Cdd:COG3857 369 RLLKTGllrplSREEIDRLENYVLaygirgrrwlERYLEEEEELTDEEEEDLERlNELRDRLLEPLLPLRerlkkaktvr 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 463 ELIDALAQ--ETTDMPLHVQTDRVIKDSGLRAMYEqekgEKGQTR---IENLEELVTatrqfsynEEDEDLMPLQAF--- 534
Cdd:COG3857 449 EWAEALYEflEELGVPEKLEEWREAEEAGDLEEAR----EHEQAWnalIELLDELVE--------VLGDEKLSLEEFlri 516
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 535 LSHAALEAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGVEEGMFPSQM------------ALDEGG---------RLE 593
Cdd:COG3857 517 LESGLEELTFGLIPPSLDQVQVGGLDRARGLDFKAVFVLGLNEGVFPARPredgllsdeereRLNELGlelpptsreRLL 596
|
650 660 670 680
....*....|....*....|....*....|....*....|....*.
gi 488972480 594 EERRLAYVGVTRAMQKLTLTYAETRRLyGKEVyhRPSRFIGELPQE 639
Cdd:COG3857 597 EERFLFYRALTRASERLYLSYPLADEE-GKAL--LPSPLIDRLREL 639
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
10-308 |
1.40e-22 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 103.11 E-value: 1.40e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 10 LNDKQREAVAASRTNMLVLAGAGSGKTRVLVHRIAWLLSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTTqgGMWVGT 89
Cdd:PRK11054 197 LNPSQARAVVNGEDSLLVLAGAGSGKTSVLVARAGWLLARGQAQPEQILLLAFGRQAAEEMDERIRERLGTE--DITART 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 90 FHGLAHRLLRAHH----------LDANLPQDFQILDSEDQLRLLKRLIKAMnldeKQWPPRQAMWYI---NSQKDEGL-- 154
Cdd:PRK11054 275 FHALALHIIQQGSkkvpviskleNDSKARHALLIAEWRKQCSEKKAQAKGW----RQWLTEELQWDVpegNFWDDEKLqr 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 155 -------------RPHH------IQSYGNPVEQTWQK-------VYQAYQEACDRAGLVDFAELLLRAHELwLNKphilq 208
Cdd:PRK11054 351 rlasrlerwvslmRMHGgsqaemIAQAPEEVRDLFQKrlklmapLLKAWKKALKAENAVDFSGLIHQAVNY-LEK----- 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 209 hyrERFTN----ILVDEFQDtnnIQYAWIRLLAGDTGK-----VMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRL 279
Cdd:PRK11054 425 ---GRFISpwkhILVDEFQD---ISPQRAALLAALRKQnsqttLFAVGDDWQAIYRFSGADLSLTTAFHERFGEGDRCHL 498
|
330 340
....*....|....*....|....*....
gi 488972480 280 EQNYRSTSNILSAANALIENNNGRLGKKL 308
Cdd:PRK11054 499 DTTYRFNSRIGEVANRFIQQNPHQLKKPL 527
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
14-139 |
7.19e-19 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 83.42 E-value: 7.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 14 QREAV--AASRTNMLVLAGAGSGKTRVLVHRIAWLLSVeNCSPYSIMAVTFTNKAAAEMRHRIGQ-------LMGTTQGG 84
Cdd:pfam13245 1 QREAVrtALPSKVVLLTGGPGTGKTTTIRHIVALLVAL-GGVSFPILLAAPTGRAAKRLSERTGLpastihrLLGFDDLE 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 488972480 85 MwvGTFHGLAHRLLRAHHLdanLPQDFQILDSEDQLRLLKRLIKAMNL----DEKQWPP 139
Cdd:pfam13245 80 A--GGFLRDEEEPLDGDLL---IVDEFSMVDLPLAYRLLKALPDGAQLllvgDPDQLPS 133
|
|
| PRK13909 |
PRK13909 |
RecB-like helicase; |
29-300 |
2.21e-18 |
|
RecB-like helicase;
Pssm-ID: 237554 [Multi-domain] Cd Length: 910 Bit Score: 90.03 E-value: 2.21e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 29 AGAGSGKTRVLVHR-IAWLLSVENcsPYSIMAVTFTNKAAAEMRHRI----------------GQLMGTT---------- 81
Cdd:PRK13909 5 ASAGSGKTFALSVRfLALLFKGAN--PSEILALTFTKKAANEMKERIidtllnlekekeeselNELEEKLglskeellnk 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 82 ---------QGGMWVGTFHGLAHRLLRAHHLDANLPQDFQIlDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINS---- 148
Cdd:PRK13909 83 rdkvyqeflNSELKISTIDAFFQKILRKFCLNLGLSPDFSI-KEDTKEELNEKFLSALSKEELLELLAFIKQCESKknns 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 149 ---------QKDEGLRphHIQSYGNPVEQTWQKV----------YQAYQEACDRAG-LVDF--AELLLRAHELWLNK--- 203
Cdd:PRK13909 162 ffelleklyEKNNELK--LFEKAKNPIEFDEEKFleelrslkqqIQSIETASKNAKkAFKKedFEELLNSSKTWLEKese 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 204 --------------------------------------PHILQHYRE--------------------------------- 212
Cdd:PRK13909 240 yryfkklyneeldaefeelknalkryydakenyklsklFKLLQLYKEaknelnkkknaldfddiskkvyellgeeeidkd 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 213 --------RFTNILVDEFQDTNNIQYAWIR-----LLAG----DTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFpGAE 275
Cdd:PRK13909 320 flyfrldsKISHILIDEFQDTSVLQYKILLplideIKSGegqkKFRSFFYVGDVKQSIYRFRGGKKELFDKVSKDF-KQK 398
|
410 420
....*....|....*....|....*
gi 488972480 276 TIRLEQNYRSTSNILSAANALIENN 300
Cdd:PRK13909 399 VDNLDTNYRSAPLIVDFVNEVFKKK 423
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
24-70 |
3.74e-10 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 56.76 E-value: 3.74e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 488972480 24 NMLVLAGAGSGKTRVLVHRIAWLLSvencSPYSIMAVTFTNKAAAEM 70
Cdd:cd17912 1 NILHLGPTGSGKTLVAIQKIASAMS----SGKSVLVVTPTKLLAHEI 43
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
12-370 |
4.21e-10 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 62.93 E-value: 4.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 12 DKQREAVAASRT--NMLVLAGAGSGKTRVLVHRIAWLLSVENCSPysiMAVTFTNKA-AAEMRHRIGQ-LMGTTQGGMW- 86
Cdd:COG3972 161 DLQQERIARSIPdgPQRIRGVAGSGKTVLLAAKAAYLALKHPGWR---ILVTCFNRSlADHLRDLIPRfLRRFSNGEPEd 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 87 ---VGTFHGLAHRLLRAHHLDanlpqdfqildsedqlrllkrlikamnldekqwPPRQamwyinSQKDEglrphhiqsyg 163
Cdd:COG3972 238 nvkLIVFHAWGGKLLKQYGIP---------------------------------PLTF------SQPNE----------- 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 164 npveqtwqkvyqAYQEACDRaglvdfaelLLRAhelwLNKPHILQHYRErftnILVDEFQDTNNIqyaWIRL----LAGD 239
Cdd:COG3972 268 ------------AFDEACKA---------LLEA----IQGEIIPPIYDA----ILIDEAQDFEPE---FLRLlyqlLKPP 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 240 TGKVMIVGDDDQSIYG---WRGAQVENIQRflndfpgaETIRLEQNYRSTSNILSAANALI---------------ENNN 301
Cdd:COG3972 316 KKRLIWAYDEAQNIYGrkiPSAGGIPAGIG--------RDTILKKNYRNTRPILTFAHAFGmgllrppgllqgdaeDYEV 387
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488972480 302 GRLGKK------LWTDGADGEPISLYCAFNDLDEARFVVNRIKTW-QENGGALEQCAILYRSNAQSRVLEEALLQA 370
Cdd:COG3972 388 ERPGDKvtlirpPEPAGRKGPLPEFKKYDDRAEELEAIAEEIKKNlRDEGLRPSDIAVIYLGNNEAKELGDRLAAA 463
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
552-613 |
2.38e-09 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 54.75 E-value: 2.38e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488972480 552 DAVQLMTLHSAKGLEFPQVFIVGVEEGMfpsqmaldeggrleEERRLAYVGVTRAMQKLTLT 613
Cdd:cd18786 41 QLVGAITIDSSQGLTFDVVTLYLPTANS--------------LTPRRLYVALTRARKRLVIY 88
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
213-367 |
3.97e-09 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 59.88 E-value: 3.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 213 RFTNILVDEFQDTNNIQYAWIRLLaGDTGKVMIVGDDDQSIYGWRGAqvENIQRFLNDFPG--AETIRLEQNYRSTSNIL 290
Cdd:COG3973 469 TYGHVVVDEAQDLSPMQWRVLKRR-FPSASFTIVGDLAQAIHPYRGA--ESWEEVLEPLGGdrARLVELTKSYRSTAEIM 545
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 291 SAANALIENNNG---------RLGKKLWTDGADGEPislycafnDLDEArfVVNRIKTWQENGGalEQCAILYRSNAQSR 361
Cdd:COG3973 546 EFANRVLRAAGPdlpppesvrRHGEPPRVVRVPSEA--------ELAAA--VVEAVRELLAEGE--GTIAVICKTAREAE 613
|
....*.
gi 488972480 362 VLEEAL 367
Cdd:COG3973 614 ALYAAL 619
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
557-613 |
8.73e-08 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 49.11 E-value: 8.73e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 488972480 557 MTLHSAKGLEFPQVFIVGVEegmfpsqmaLDEGGRLEEERRLAYVGVTRAMQKLTLT 613
Cdd:pfam13538 5 LTVHKAQGSEFPAVFLVDPD---------LTAHYHSMLRRRLLYTAVTRARKKLVLV 52
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
537-617 |
7.26e-07 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 52.56 E-value: 7.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 537 HAALEAGEG------QADTWQDAVQLMTLHSAKGLEFPQVFIVGVEEgmfpsqmaldEGGRLEEERRLAYVGVTRAMQKL 610
Cdd:COG3973 616 YAALKAGLPvtliddESEELEAGVVVLPAYLAKGLEFDAVVVVDPDE----------IVYESPRGRRLLYVALTRATHRL 685
|
....*..
gi 488972480 611 TLTYAET 617
Cdd:COG3973 686 TVLHTGE 692
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
211-606 |
1.61e-06 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 51.90 E-value: 1.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 211 RERFTNILVDEFQDTNNIQYAWIRLLAG---DTGKVMIvGDDDQSIYGWRGAQVENIQRFLNDFPGAETirLEQNYRSTS 287
Cdd:PRK10876 375 RTRYPVAMIDEFQDTDPQQYRIFRRIYRhqpETALLLI-GDPKQAIYAFRGADIFTYMKARSEVSAHYT--LDTNWRSAP 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 288 NILSAANALI--------------------ENNNGRL----GKK-----LWTDGADGEPISLYCAFndldEARFVVNRIK 338
Cdd:PRK10876 452 GMVNSVNKLFsqtddpflfreipfipvkaaGKNQALRfvvkGETqpamkFWLMEGEGVGVGDYQQT----MAQQCAAQIR 527
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 339 TWQENGGalEQCAILYRSNAQSRVleeallQASmpyRIYGGMRffERQE---IKDALSYLRL----IANRndDAAFErvv 411
Cdd:PRK10876 528 DWLQAGQ--RGEALLMNGDDSRPV------RAS---DITVLVR--SRQEaalIRDALTLLAIpsvyLSNR--DSVFE--- 589
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 412 ntptrgigdrtldvvrqTSRDRQLtLW--QASRELLKEKALAGRAASALqrfMEL----IDALAQETTdmplhvQTDRVI 485
Cdd:PRK10876 590 -----------------TLEAQEM-LWllQAVLAPERERTLRSALATSM---MGLdaldIDALNNDER------AWDALV 642
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 486 KD-SGLRAMYeQEKGEkgqtrIENLEELVTAtRQFSYN----EEDE----DLMPLQAFLSHAALEAG------------- 543
Cdd:PRK10876 643 EEfDGYRQIW-RKRGV-----LPMLRALMSA-RNIAENllatAGGErrltDILHIGELLQEASSQLDsehalvrwlaqqi 715
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 544 ---EGQADTWQ-------DAVQLMTLHSAKGLEFPQV---FIVG--VEEGMF----------------PSQMALDEGGRL 592
Cdd:PRK10876 716 lepDSQASSQQlrlesdkHLVQIVTIHKSKGLEYPLVwlpFITNfrVQDQAFyhdrhsfeavldlnaaEESVALAEEERL 795
|
490
....*....|....
gi 488972480 593 EEERRLAYVGVTRA 606
Cdd:PRK10876 796 AEDLRLLYVALTRS 809
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
202-249 |
2.08e-06 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 45.97 E-value: 2.08e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 488972480 202 NKPHILQHYrerftnILVDEFQDTNNIQYAW----IRLLAGDTGKVMIVGDD 249
Cdd:cd17912 36 TKLLAHEIL------IVIDEIQ*ILDPAAGWawatRALLGLKAEKVIGVGAT 81
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
10-76 |
2.53e-05 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 47.28 E-value: 2.53e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 10 LNDKQREAVAA---SRTNMLVLAGAGSGKTRvLVHRIAWLLSVENcspYSIMAVTFTNKAAAEMRHRIGQ 76
Cdd:COG0507 125 LSDEQREAVALaltTRRVSVLTGGAGTGKTT-TLRALLAALEALG---LRVALAAPTGKAAKRLSESTGI 190
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
544-612 |
7.76e-05 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 41.39 E-value: 7.76e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488972480 544 EGQADTWQDAVQL--MTLHSAKGLEFPQVFIVgveegmfpsqmaLDEGGRLEEeRRLAYVGVTRAMQKLTL 612
Cdd:cd18809 21 KGGVDALNERLQAyaMTIHKSQGSEFDRVIVV------------LPTSHPMLS-RGLLYTALTRARKLLTL 78
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
557-634 |
5.20e-04 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 43.04 E-value: 5.20e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488972480 557 MTLHSAKGLEFPQVFIVgveegmfpsqmaLDEGGRLEEERRLAYVGVTRAMQKLTLTYaeTRRLYGKEVYHRPSRFIG 634
Cdd:COG0507 445 ITVHKSQGSTFDRVILV------------LPSEHSPLLSRELLYTALTRARELLTLVG--DRDALARAVRRDTARATG 508
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
9-75 |
5.64e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 38.70 E-value: 5.64e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488972480 9 SLNDKQREAVAASRTN----MLVLAGAGSGKTRVLVH-RIAWllsveNCSPYSIMAVTFTNKAAAEMRHRIG 75
Cdd:pfam13604 1 TLNAEQAAAVRALLTSgdrvAVLVGPAGTGKTTALKAlREAW-----EAAGYRVIGLAPTGRAAKVLGEELG 67
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
13-139 |
8.56e-03 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 37.53 E-value: 8.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488972480 13 KQREAV-AASRTNMLVLAG-AGSGKTRVLVhRIAWLLSVENcspYSIMAVTFTNKAAAEMRHRIGQLMGTTqggmwvgtf 90
Cdd:cd17933 1 EQKAAVrLVLRNRVSVLTGgAGTGKTTTLK-ALLAALEAEG---KRVVLAAPTGKAAKRLSESTGIEASTI--------- 67
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488972480 91 hglaHRLLRA-------HHLDAN-LPQDFQILDsE----DqLRLLKRLIKAMNL--------DEKQWPP 139
Cdd:cd17933 68 ----HRLLGInpggggfYYNEENpLDADLLIVD-EasmvD-TRLMAALLSAIPAgarlilvgDPDQLPS 130
|
|
| |
