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Conserved domains on  [gi|488409365|ref|WP_002478750|]
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MULTISPECIES: helix-turn-helix domain-containing protein [Staphylococcus]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 11443570)

helix-turn-helix domain-containing protein such as an XRE (Xenobiotic Response Element) family transcriptional regulator

Gene Ontology:  GO:0003677
PubMed:  37972151

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-76 1.32e-20

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


:

Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 78.50  E-value: 1.32e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488409365   1 MKLAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELLTGENMSNFTKELNE 76
Cdd:COG1396    6 KALGERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGADEELPEALLSE 81
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-76 1.32e-20

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 78.50  E-value: 1.32e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488409365   1 MKLAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELLTGENMSNFTKELNE 76
Cdd:COG1396    6 KALGERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGADEELPEALLSE 81
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 4-61 5.41e-18

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 71.43  E-value: 5.41e-18
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 488409365   4 AEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDEL 61
Cdd:cd00093    1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
7-61 2.20e-16

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 67.16  E-value: 2.20e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 488409365     7 IKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDEL 61
Cdd:smart00530   2 LKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 7-61 3.61e-16

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 66.41  E-value: 3.61e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 488409365    7 IKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDEL 61
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
couple_hipB TIGR03070
transcriptional regulator, y4mF family; Members of this family belong to a clade of ...
 2-57 1.89e-08

transcriptional regulator, y4mF family; Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions]


Pssm-ID: 213767 [Multi-domain]  Cd Length: 58  Bit Score: 46.88  E-value: 1.89e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 488409365    2 KLAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNIT 57
Cdd:TIGR03070   2 QIGILVRARRKALGLTQADLADLAGVGLRFIRDLENGKPTVRLDKVLRVLDALGLE 57
PRK09706 PRK09706
transcriptional repressor DicA; Reviewed
 3-65 1.11e-06

transcriptional repressor DicA; Reviewed


Pssm-ID: 182039 [Multi-domain]  Cd Length: 135  Bit Score: 44.07  E-value: 1.11e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488409365   3 LAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELLTGE 65
Cdd:PRK09706   6 LGQRIRYRRKQLKLSQRSLAKAVKVSHVSISQWERDETEPTGKNLFALAKALQCSPTWLLFGD 68
lysogeny_AimR NF038310
AimR family lysis-lysogeny pheromone receptor; The founding member of this family, AimR ...
 7-55 7.95e-03

AimR family lysis-lysogeny pheromone receptor; The founding member of this family, AimR (arbitrium receptor), is a DNA-binding phage regulatory protein that acts as a receptor for a 6-amino acid signaling peptide cleaved from the C-terminus of AimP. AimR controls expression of AimX, the third member of the quorum sensing-like arbitrium system and an inhibitor of phage lysogeny.


Pssm-ID: 468467  Cd Length: 363  Bit Score: 34.43  E-value: 7.95e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 488409365   7 IKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFN 55
Cdd:NF038310   1 IKNDLESKGITNRKLAKKIGVSKSTLSKFFNGKGEISFDSLLKILRVLY 49
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-76 1.32e-20

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 78.50  E-value: 1.32e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488409365   1 MKLAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELLTGENMSNFTKELNE 76
Cdd:COG1396    6 KALGERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGADEELPEALLSE 81
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-66 3.19e-19

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 74.50  E-value: 3.19e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488409365   1 MKLAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELLTGEN 66
Cdd:COG1476    3 KKLGNRLKELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELFSLEE 68
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 4-61 5.41e-18

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 71.43  E-value: 5.41e-18
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 488409365   4 AEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDEL 61
Cdd:cd00093    1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
7-61 2.20e-16

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 67.16  E-value: 2.20e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 488409365     7 IKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDEL 61
Cdd:smart00530   2 LKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 7-61 3.61e-16

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 66.41  E-value: 3.61e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 488409365    7 IKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDEL 61
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
 3-60 2.82e-15

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 64.57  E-value: 2.82e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 488409365   3 LAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDE 60
Cdd:COG1813   13 YGERIREAREARGLSQEELAEKLGVSESTIRRIERGEATPSLDTLRKLEKALGISLAE 70
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 5-66 4.22e-14

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 61.54  E-value: 4.22e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488409365    5 EQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELLTGEN 66
Cdd:pfam12844   2 ERLRKAREERGLTQEELAERLGISRSQLSAIENGKSVPPAETLYKIAELLGVPANWLLQGEG 63
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
4-53 1.47e-11

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 54.94  E-value: 1.47e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 488409365   4 AEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQM 53
Cdd:COG2944    8 PEEIRALRERLGLSQAEFAALLGVSVSTVRRWEQGRRKPSGAALKLLRLL 57
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
 1-66 2.33e-09

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 50.40  E-value: 2.33e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488409365   1 MKLAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELLTGEN 66
Cdd:COG3620   16 DTLGEALRLMRKELGLSQLPVAELVGVSQSDILRIESGKRDPTVSTLEKIAEALGKELSAVLVVDD 81
couple_hipB TIGR03070
transcriptional regulator, y4mF family; Members of this family belong to a clade of ...
 2-57 1.89e-08

transcriptional regulator, y4mF family; Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions]


Pssm-ID: 213767 [Multi-domain]  Cd Length: 58  Bit Score: 46.88  E-value: 1.89e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 488409365    2 KLAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNIT 57
Cdd:TIGR03070   2 QIGILVRARRKALGLTQADLADLAGVGLRFIRDLENGKPTVRLDKVLRVLDALGLE 57
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 3-61 2.04e-08

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 47.14  E-value: 2.04e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409365    3 LAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIE-PNAQMIVNLAQMFNITTDEL 61
Cdd:pfam13560   2 LGARLRRLRERAGLSQEALARRLGVSRSTLSRLETGRRGrPSPAVVERLARALGVDGAER 61
PRK09706 PRK09706
transcriptional repressor DicA; Reviewed
 3-65 1.11e-06

transcriptional repressor DicA; Reviewed


Pssm-ID: 182039 [Multi-domain]  Cd Length: 135  Bit Score: 44.07  E-value: 1.11e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488409365   3 LAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELLTGE 65
Cdd:PRK09706   6 LGQRIRYRRKQLKLSQRSLAKAVKVSHVSISQWERDETEPTGKNLFALAKALQCSPTWLLFGD 68
RodZ COG1426
Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell ...
 1-62 4.16e-06

Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441035 [Multi-domain]  Cd Length: 71  Bit Score: 41.33  E-value: 4.16e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488409365   1 MKLAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIE--PNAQ----MIVNLAQMFNITTDELL 62
Cdd:COG1426    4 ETIGELLRQAREAKGLSLEDVAERTKISVSYLEAIEEGDFDalPGPVyvrgFLRSYARALGLDPEELL 71
VapI COG3093
Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense ...
 10-62 1.12e-05

Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense mechanisms];


Pssm-ID: 442327 [Multi-domain]  Cd Length: 87  Bit Score: 40.56  E-value: 1.12e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 488409365  10 YRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELL 62
Cdd:COG3093   17 FLEPLGLSQTELAKALGVSRQRISEILNGKRAITADTALRLARAFGTSAEFWL 69
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 4-50 3.24e-05

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 39.92  E-value: 3.24e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 488409365    4 AEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMiVNL 50
Cdd:TIGR03830  67 GPEIRRIRKKLGLSQREAAELLGGGVNAFSRYERGEVRPSKAL-DKL 112
DeoR COG2390
DNA-binding transcriptional regulator LsrR, DeoR family [Transcription];
13-52 3.66e-05

DNA-binding transcriptional regulator LsrR, DeoR family [Transcription];


Pssm-ID: 441955 [Multi-domain]  Cd Length: 301  Bit Score: 40.88  E-value: 3.66e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 488409365  13 EQGLTQDQLAAELHTTRQTVSK-----WEQG----SIEPNAQMIVNLAQ 52
Cdd:COG2390    8 VEGLTQREIAERLGISRRTVSRllaeaREEGlvriSITDPLAGLLELER 56
tfx PRK03975
putative transcriptional regulator; Provisional
 6-44 1.42e-04

putative transcriptional regulator; Provisional


Pssm-ID: 179690 [Multi-domain]  Cd Length: 141  Bit Score: 38.33  E-value: 1.42e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 488409365   6 QIK--KYRKeQGLTQDQLAAELHTTRQTVSkweqgSIEPNA 44
Cdd:PRK03975  11 QIEvlRLRE-RGLTQQEIADILGTSRANVS-----SIEKRA 45
COG1356 COG1356
Transcriptional regulator [Transcription];
9-44 1.55e-04

Transcriptional regulator [Transcription];


Pssm-ID: 440967 [Multi-domain]  Cd Length: 139  Bit Score: 38.30  E-value: 1.55e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 488409365   9 KYRkEQGLTQDQLAAELHTTRQTVSkweqgSIEPNA 44
Cdd:COG1356   18 ALR-ERGLTQQEIADILGTSRANVS-----SIEKSA 47
COG1395 COG1395
Predicted transcriptional regulator [Transcription];
5-55 1.95e-04

Predicted transcriptional regulator [Transcription];


Pssm-ID: 441005 [Multi-domain]  Cd Length: 313  Bit Score: 39.05  E-value: 1.95e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 488409365   5 EQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFN 55
Cdd:COG1395  130 EKLRELREERGLSLGELASELGVSRRTISKYERGEMDASIEVALKLEEILG 180
PRK04140 PRK04140
transcriptional regulator;
5-77 2.32e-04

transcriptional regulator;


Pssm-ID: 235224 [Multi-domain]  Cd Length: 317  Bit Score: 38.68  E-value: 2.32e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488409365   5 EQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFN--ITTD-ELLTGENMSNFTKELNET 77
Cdd:PRK04140 129 DVLREAREELGLSLGELASELGVSRRTISKYENGGMNASIEVAIKLEEILDvpLTKPiDILEKVRDDEVTPEDPEE 204
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
 4-65 2.34e-03

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 35.87  E-value: 2.34e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488409365   4 AEQIKKYRKEQGLTQDQLA-----AELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELLTGE 65
Cdd:PRK13355   5 AERLKQAMKARGLKQEDLVhaaeaRGVKLGKSHISQYVSGKTGPRRDVLPFLAAILGVSEDWLLGGE 71
PHA01976 PHA01976
helix-turn-helix protein
 1-64 2.62e-03

helix-turn-helix protein


Pssm-ID: 177330 [Multi-domain]  Cd Length: 67  Bit Score: 33.78  E-value: 2.62e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488409365   1 MKLAEQIKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFNITTDELLTG 64
Cdd:PHA01976   1 MSFAIQLIKARNARAWSAPELSRRAGVRHSLIYDFEADKRLPNLKTLLRLADALGVTLDWLCGR 64
lysogeny_AimR NF038310
AimR family lysis-lysogeny pheromone receptor; The founding member of this family, AimR ...
 7-55 7.95e-03

AimR family lysis-lysogeny pheromone receptor; The founding member of this family, AimR (arbitrium receptor), is a DNA-binding phage regulatory protein that acts as a receptor for a 6-amino acid signaling peptide cleaved from the C-terminus of AimP. AimR controls expression of AimX, the third member of the quorum sensing-like arbitrium system and an inhibitor of phage lysogeny.


Pssm-ID: 468467  Cd Length: 363  Bit Score: 34.43  E-value: 7.95e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 488409365   7 IKKYRKEQGLTQDQLAAELHTTRQTVSKWEQGSIEPNAQMIVNLAQMFN 55
Cdd:NF038310   1 IKNDLESKGITNRKLAKKIGVSKSTLSKFFNGKGEISFDSLLKILRVLY 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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