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Conserved domains on  [gi|488409192|ref|WP_002478577|]
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MULTISPECIES: DUF896 domain-containing protein [Staphylococcus]

Protein Classification

DUF896 domain-containing protein( domain architecture ID 10008366)

DUF896 family protein similar to Bacillus subtilis SOS response protein YnzC and Lactococcus lactis UPF0291 protein YlaC

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YnzC COG4224
Uncharacterized conserved protein YnzC, UPF0291/DUF896 family [Function unknown];
1-72 6.08e-25

Uncharacterized conserved protein YnzC, UPF0291/DUF896 family [Function unknown];


:

Pssm-ID: 443368  Cd Length: 75  Bit Score: 87.98  E-value: 6.08e-25
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488409192  1 MNNLLERINQLANKEKIQTLSIEEKQEQQALRQDYLAMIRGQVLHTFSTMKVLDPLGQDVTPDKVYDLREQY 72
Cdd:COG4224   3 MKEKIDRINELAKKAKEEGLTEEEKKEQKKLRQEYLKNFRGSFRNQLENIKVVDPEGNDVTPEKLKEIQRKK 74
 
Name Accession Description Interval E-value
YnzC COG4224
Uncharacterized conserved protein YnzC, UPF0291/DUF896 family [Function unknown];
1-72 6.08e-25

Uncharacterized conserved protein YnzC, UPF0291/DUF896 family [Function unknown];


Pssm-ID: 443368  Cd Length: 75  Bit Score: 87.98  E-value: 6.08e-25
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488409192  1 MNNLLERINQLANKEKIQTLSIEEKQEQQALRQDYLAMIRGQVLHTFSTMKVLDPLGQDVTPDKVYDLREQY 72
Cdd:COG4224   3 MKEKIDRINELAKKAKEEGLTEEEKKEQKKLRQEYLKNFRGSFRNQLENIKVVDPEGNDVTPEKLKEIQRKK 74
DUF896 pfam05979
Bacterial protein of unknown function (DUF896); In B. subtilis, one small SOS response operon ...
3-64 2.82e-24

Bacterial protein of unknown function (DUF896); In B. subtilis, one small SOS response operon under the control of LexA, the yneA operon, is comprised of three genes: yneA, yneB, and ynzC. This family consists of several short, hypothetical bacterial proteins of unknown function. These proteins are mainly found in gram-positive firmicutes. Structures show that the N-terminus is composed of two alpha helices forming a helix-loop-helix motif. The structure of ynzC from B. subtilis forms a trimeric complex. Structural modelling suggests this domain may bind nucleic acids. This family is also known as UPF0291.


Pssm-ID: 428703  Cd Length: 62  Bit Score: 86.02  E-value: 2.82e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488409192   3 NLLERINQLANKEKIQTLSIEEKQEQQALRQDYLAMIRGQVLHTFSTMKVLDPLGQDVTPDK 64
Cdd:pfam05979  1 EKIDRINELAKKAKTEGLTEEEKAEQKKLRKEYLKAFRASFKSQLENVKVVDPNGNDVTPEK 62
PRK02539 PRK02539
DUF896 family protein;
5-71 5.19e-15

DUF896 family protein;


Pssm-ID: 179440  Cd Length: 85  Bit Score: 63.37  E-value: 5.19e-15
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488409192  5 LERINQLANKEKIQTLSIEEKQEQQALRQDYLAMIRGQVLHTFSTMKVLDPLGQDVTPDKVYDLREQ 71
Cdd:PRK02539  6 IARINELAKKKKTEGLTGEEKVEQAKLREEYIEGYRRSVRHHIEGIKIVDEEGNDVTPEKLRQVQRE 72
 
Name Accession Description Interval E-value
YnzC COG4224
Uncharacterized conserved protein YnzC, UPF0291/DUF896 family [Function unknown];
1-72 6.08e-25

Uncharacterized conserved protein YnzC, UPF0291/DUF896 family [Function unknown];


Pssm-ID: 443368  Cd Length: 75  Bit Score: 87.98  E-value: 6.08e-25
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488409192  1 MNNLLERINQLANKEKIQTLSIEEKQEQQALRQDYLAMIRGQVLHTFSTMKVLDPLGQDVTPDKVYDLREQY 72
Cdd:COG4224   3 MKEKIDRINELAKKAKEEGLTEEEKKEQKKLRQEYLKNFRGSFRNQLENIKVVDPEGNDVTPEKLKEIQRKK 74
DUF896 pfam05979
Bacterial protein of unknown function (DUF896); In B. subtilis, one small SOS response operon ...
3-64 2.82e-24

Bacterial protein of unknown function (DUF896); In B. subtilis, one small SOS response operon under the control of LexA, the yneA operon, is comprised of three genes: yneA, yneB, and ynzC. This family consists of several short, hypothetical bacterial proteins of unknown function. These proteins are mainly found in gram-positive firmicutes. Structures show that the N-terminus is composed of two alpha helices forming a helix-loop-helix motif. The structure of ynzC from B. subtilis forms a trimeric complex. Structural modelling suggests this domain may bind nucleic acids. This family is also known as UPF0291.


Pssm-ID: 428703  Cd Length: 62  Bit Score: 86.02  E-value: 2.82e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488409192   3 NLLERINQLANKEKIQTLSIEEKQEQQALRQDYLAMIRGQVLHTFSTMKVLDPLGQDVTPDK 64
Cdd:pfam05979  1 EKIDRINELAKKAKTEGLTEEEKAEQKKLRKEYLKAFRASFKSQLENVKVVDPNGNDVTPEK 62
PRK02539 PRK02539
DUF896 family protein;
5-71 5.19e-15

DUF896 family protein;


Pssm-ID: 179440  Cd Length: 85  Bit Score: 63.37  E-value: 5.19e-15
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488409192  5 LERINQLANKEKIQTLSIEEKQEQQALRQDYLAMIRGQVLHTFSTMKVLDPLGQDVTPDKVYDLREQ 71
Cdd:PRK02539  6 IARINELAKKKKTEGLTGEEKVEQAKLREEYIEGYRRSVRHHIEGIKIVDEEGNDVTPEKLRQVQRE 72
PRK01546 PRK01546
hypothetical protein; Provisional
4-78 5.51e-10

hypothetical protein; Provisional


Pssm-ID: 100891  Cd Length: 79  Bit Score: 50.41  E-value: 5.51e-10
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488409192  4 LLERINQLANKEKIQTLSIEEKQEQQALRQDYLAMIRGQVLHTFSTMKVLDPLGQDVTPDKVYDLREQyDNIQEN 78
Cdd:PRK01546  6 LVERINFLAKKAKAEGLTEEEQRERQSLREQYLKGFRQNMLNELKGIKVVNEQGTDVTPAKLKALKKQ-DNAKLN 79
PRK01631 PRK01631
hypothetical protein; Provisional
1-67 4.83e-09

hypothetical protein; Provisional


Pssm-ID: 167247  Cd Length: 76  Bit Score: 47.80  E-value: 4.83e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488409192  1 MNNLLERINQLANKEKIQTLSIEEKQEQQALRQDYLAMIRGQVLHTFSTMKVLDPLGQDVTPDKVYD 67
Cdd:PRK01631  1 MKNILFRINELSKKEKATGLTVDEKQEQQMLRQNYTQTFRGSLDSILLNTKIVDQNGLNVTPAALQD 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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