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Conserved domains on  [gi|488409182|ref|WP_002478567|]
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MULTISPECIES: L-lactate permease [Staphylococcus]

Protein Classification

L-lactate permease( domain architecture ID 10004073)

L-lactate permease plays a role in L-lactate utilization by transporting L-lactate across the membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
11-533 5.53e-150

L-lactate permease [Energy production and conversion];


:

Pssm-ID: 441227  Cd Length: 520  Bit Score: 439.95  E-value: 5.53e-150
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  11 NMLISAIVAAVPIILFLLCLTVFKMKGVYAALTTLIVTALVAMICFKLPARIAGGATFEGFYQGIiPIGFIVIMAVWLYK 90
Cdd:COG1620    2 SLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGL-PILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  91 IATESGQFNIVQDSIASISQDQRIQLLLIGYLFNGFLEGAAGFGVPIAICAVLLMQLGFKALPAAMYCLVANAAAGAYGA 170
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 171 VGIPIAitdTLNLAGGVKASQVALIGNLTLGLISFFVPFLLMFIIDGLKGVKETFPATLIAASVFTGLQVLIAAFAGPEL 250
Cdd:COG1620  161 VGTPII---VGAQVTGLDALEIGAMVGRQLPILSLLIPFLLVWILDGWRGIKEVWPAALVAGLSFAVPQFLTANFLGPEL 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 251 ADIIPGLGAMVALALFSRKFQPKNIFRLEDNEAVGK----VEKHSIKQIVYGWSPFIILTVIVMVWSL-PAFKALfekgg 325
Cdd:COG1620  238 PDIIAGLVGLAALVLFLRFWKPKEIWDFAPEEEWPAeeedAEKLSAMSLLKAWSPYLLLIVLLVLTRLpPPVKAL----- 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 326 aLSALVVNFNAPGTMNNVTHHpNVLTFNFIAQTGTAILVTAIITILIAKhMSFKTAGKLLGVTVKELWVSVLTICFILAV 405
Cdd:COG1620  313 -LNSTTLKIPWPGLLGAGTTG-ASYSFNPLYAPGTAILLAALITILLLR-MSPGQAKRAFKETLKQLRGPILTLAFVLAL 389
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 406 SKITTYGGLSNAMGQGIA-KTGAIFPLLSPVLGWIGVFMTGSVVNNNSLFAPIQASVATQIGTKGSLLVAANVAGGVTAK 484
Cdd:COG1620  390 AYVMNYSGMPATLGLALAaATGAAFPFFAPFLGWLGVFITGSDTSSNALFGGLQFTTAEQLGLSPTLIVAAQSVGGVMGK 469
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*....
gi 488409182 485 IVSPQSIAIATAAVNKVGKESELMKMAMRFSIGLLIFACIWTFMLSLFV 533
Cdd:COG1620  470 MISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
 
Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
11-533 5.53e-150

L-lactate permease [Energy production and conversion];


Pssm-ID: 441227  Cd Length: 520  Bit Score: 439.95  E-value: 5.53e-150
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  11 NMLISAIVAAVPIILFLLCLTVFKMKGVYAALTTLIVTALVAMICFKLPARIAGGATFEGFYQGIiPIGFIVIMAVWLYK 90
Cdd:COG1620    2 SLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGL-PILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  91 IATESGQFNIVQDSIASISQDQRIQLLLIGYLFNGFLEGAAGFGVPIAICAVLLMQLGFKALPAAMYCLVANAAAGAYGA 170
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 171 VGIPIAitdTLNLAGGVKASQVALIGNLTLGLISFFVPFLLMFIIDGLKGVKETFPATLIAASVFTGLQVLIAAFAGPEL 250
Cdd:COG1620  161 VGTPII---VGAQVTGLDALEIGAMVGRQLPILSLLIPFLLVWILDGWRGIKEVWPAALVAGLSFAVPQFLTANFLGPEL 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 251 ADIIPGLGAMVALALFSRKFQPKNIFRLEDNEAVGK----VEKHSIKQIVYGWSPFIILTVIVMVWSL-PAFKALfekgg 325
Cdd:COG1620  238 PDIIAGLVGLAALVLFLRFWKPKEIWDFAPEEEWPAeeedAEKLSAMSLLKAWSPYLLLIVLLVLTRLpPPVKAL----- 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 326 aLSALVVNFNAPGTMNNVTHHpNVLTFNFIAQTGTAILVTAIITILIAKhMSFKTAGKLLGVTVKELWVSVLTICFILAV 405
Cdd:COG1620  313 -LNSTTLKIPWPGLLGAGTTG-ASYSFNPLYAPGTAILLAALITILLLR-MSPGQAKRAFKETLKQLRGPILTLAFVLAL 389
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 406 SKITTYGGLSNAMGQGIA-KTGAIFPLLSPVLGWIGVFMTGSVVNNNSLFAPIQASVATQIGTKGSLLVAANVAGGVTAK 484
Cdd:COG1620  390 AYVMNYSGMPATLGLALAaATGAAFPFFAPFLGWLGVFITGSDTSSNALFGGLQFTTAEQLGLSPTLIVAAQSVGGVMGK 469
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*....
gi 488409182 485 IVSPQSIAIATAAVNKVGKESELMKMAMRFSIGLLIFACIWTFMLSLFV 533
Cdd:COG1620  470 MISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
Lactate_perm pfam02652
L-lactate permease; L-lactate permease is an integral membrane protein probably involved in ...
14-529 1.66e-133

L-lactate permease; L-lactate permease is an integral membrane protein probably involved in L-lactate transport.


Pssm-ID: 280762  Cd Length: 522  Bit Score: 397.90  E-value: 1.66e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   14 ISAIVAAVPIILFLLCLTVFKMKGVYAALTTLIVTALVAMICFKLPARIAGGATFEGFYQGIIPIGFIVIMAVWLYKIAT 93
Cdd:pfam02652   1 LSALVALTPILLFFFLLAVLKMKGYYAAPISLAVTVIIALLYYKMPVENTISSVLYGALYGLWPIAWIIIAAIFLYKISV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   94 ESGQFNIVQDSIASISQDQRIQLLLIGYLFNGFLEGAAGFGVPIAICAVLLMQLGFKALPAAMYCLVANAAAGAYGAVGI 173
Cdd:pfam02652  81 KSGAFEIIRSSILNISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAVGI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  174 PIAitdTLNLAGGVKASQVALIGNLTLGLISFFVPFLLMFIIDGLKGVKETFPATLIAASVFTGLQVLIAAFAGPELADI 253
Cdd:pfam02652 161 PIT---AGAGATGLSALEISSMVGFQLPFISLLIPFFLVFLMDGFKGIKETFPAVLVSGLSFAIPQFLSSNVLGPELPSI 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  254 IPGLGAMVALALFSRKFQPKNIFRLEDNEAVGKVEKHSIKQIVYGWSPFIILTVIVMVWSLPAFKALFEKGGALSALVVN 333
Cdd:pfam02652 238 LGALVSLVITALFLKFWQPKEIFRFAGKGDSGATSALRAGKIVKAWSPFVLLTAFIVLWSIPQFKALFQEGGALYTSTFN 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  334 ----------FNAPGTMNNVTHHPNVLTFNFIAQTGTAILVTAIITILIAKhMSFKTAGKLLGVTVKELWVSVLTICFIL 403
Cdd:pfam02652 318 fefpeisqliFSIPPIVGEATPFPVVFKFKLLYSPGTIIFLAALLSIFILK-VSSSDALSIFKETLKEMALPIITIIFVL 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  404 AVSKITTYGGLSNAMGQGIAKTGAIFPLLSPVLGWIGVFMTGSVVNNNSLFAPIQASVATQIGTKGSLLVAANVAGGVTA 483
Cdd:pfam02652 397 AFANLMNYSGMSKTLALALAHTGSAFTFFSPFLGWLGVFLTGSDTSSNLLFGSLQLVTAEQIGLPPVLLLAANTVGGVMG 476
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 488409182  484 KIVSPQSIAIATAAVNKVGKESELMKMAMRFSIGLLIFACIWTFML 529
Cdd:pfam02652 477 KMISPQSIAIACAAVGLAGKESDLFRKTIKYSLIYAIIVGVVAFLL 522
PRK10420 PRK10420
L-lactate permease; Provisional
4-524 4.67e-131

L-lactate permease; Provisional


Pssm-ID: 182445  Cd Length: 551  Bit Score: 392.67  E-value: 4.67e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   4 ESFNPFNNMLISAIVAAVPIILFLLCLTVFKMKGVYAALTTLIVTALVAMICFKLPARIAGGATFEGFYQGIIPIGFIVI 83
Cdd:PRK10420   6 QNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIII 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  84 MAVWLYKIATESGQFNIVQDSIASISQDQRIQLLLIGYLFNGFLEGAAGFGVPIAICAVLLMQLGFKALPAAMYCLVANA 163
Cdd:PRK10420  86 AAVFVYKISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLIVNT 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 164 AAGAYGAVGIPIAITDTLNlagGVKASQVALIGNLTLGLISFFVPFLLMFIIDGLKGVKETFPATLIAASVFTGLQVLIA 243
Cdd:PRK10420 166 APVAFGAMGIPILVAGQVT---GIDSFEIGQMVGRQLPFLTIIVLFWIMAIMDGWRGVKETWPAVVVAGGSFAIAQYLSS 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 244 AFAGPELADIIPGLGAMVALALFSRKFQPKNIFRLEDNEAVG-----KVEKHSIKQIVYGWSPFIILTVIVMVWSLPAFK 318
Cdd:PRK10420 243 NFIGPELPDIISSLVSLVCLTLFLKRWQPVRIFRFGDLGASQvdmtlAHTGYTAGQVLRAWSPFLFLTATVTLWSIPPFK 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 319 ALFEKGGALSALVVNFNAPGTMNNVTHHPNVL----------TFNFIAQTGTAILVTAIITILIAKhMSFKTAGKLLGVT 388
Cdd:PRK10420 323 ALFASGGALYEWVINIPVPYLDKLVARMPPVVseatayaavyKFDWFSATGTAILFAALLSIVWLK-MKPSDAISTFGST 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 389 VKELWVSVLTICFILAVSKITTYGGLSNAMGQGIAKTGAIFPLLSPVLGWIGVFMTGSVVNNNSLFAPIQASVATQIGTK 468
Cdd:PRK10420 402 LKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLGWLGVFLTGSDTSSNALFAALQATAAQQIGVS 481
                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 488409182 469 GSLLVAANVAGGVTAKIVSPQSIAIATAAVNKVGKESELMKMAMRFSiglLIFACI 524
Cdd:PRK10420 482 DVLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHS---LIFTCM 534
lctP TIGR00795
L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized ...
12-529 1.05e-130

L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized member of this family, from E. coli, appears to catalyze lactate:H+ uptake. Members of this family have 12 probable TMS. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 162041  Cd Length: 530  Bit Score: 390.98  E-value: 1.05e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   12 MLISAIVAAVPIILFLLCLTVFKMKGVYAALTTLIVTALVAMICFKLPARIAGGATFEGFYQGIIPIGFIVIMAVWLYKI 91
Cdd:TIGR00795   5 DWLSAIVALLPILLFFFLLAVLKLKGYYAAPISVALSVIIALFYYKMPVIMTSAAFLYGFLYGLWPIAWIIIAAIFLYKL 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   92 ATESGQFNIVQDSIASISQDQRIQLLLIGYLFNGFLEGAAGFGVPIAICAVLLMQLGFKALPAAMYCLVANAAAGAYGAV 171
Cdd:TIGR00795  85 SVKSGAFEIIRSSILSISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAV 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  172 GIPIAitdTLNLAGGVKASQVALIGNLTLGLISFFVPFLLMFIIDGLKGVKETFPATLIAASVFTGLQVLIAAFAGPELA 251
Cdd:TIGR00795 165 GIPIW---AGAQATGLSALEISSMTGFQLPFISLLIPFFLVFLMDGWKGIKETFPAVLVAGLSFAIPQFLSSNYLGPELP 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  252 DIIPGLGAMVALALFSRKFQPKNIFRLEDNEAVGKVEKHSIKQIVYGWSPFIILTVIVMVWSLPAFKALFEKGGALSALV 331
Cdd:TIGR00795 242 SILGALVSLVITALFLKFWQPKEIFRFNGKLDAGEVSAHHICKIVKAWSPFVLLTAFIVLWSIPPFKALFMKGGALIFSS 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  332 VNFNAPGTMNNV----------THHPNVLTFNFIAQTGTAILVTAIITILIAKhMSFKTAGKLLGVTVKELWVSVLTICF 401
Cdd:TIGR00795 322 FTFGSPGLSQHIfklppivnqaTNFPAVFKLLLIIATGTSILLAAIVSFFILR-VSISDAIGVFGETLKEMRLPILTIGM 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  402 ILAVSKITTYGGLSNAMGQGIAKTGAIFPLLSPVLGWIGVFMTGSVVNNNSLFAPIQASVATQIGTKGSLLVAANVAGGV 481
Cdd:TIGR00795 401 VLAFANVSNYSGMSKTLALALAHTGLAFTFFSPFLGWLGVFLTGSDTSSNLLFGSLQLLTAEQIGLPETLLLAANTVGGV 480
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 488409182  482 TAKIVSPQSIAIATAAVNKVGKESELMKMAMRFSIGLLIFACIWTFML 529
Cdd:TIGR00795 481 MGKMISPQSIAIACAAVGLVGQESDLFRKTVKYSLIYAIIVGVVALLL 528
 
Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
11-533 5.53e-150

L-lactate permease [Energy production and conversion];


Pssm-ID: 441227  Cd Length: 520  Bit Score: 439.95  E-value: 5.53e-150
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  11 NMLISAIVAAVPIILFLLCLTVFKMKGVYAALTTLIVTALVAMICFKLPARIAGGATFEGFYQGIiPIGFIVIMAVWLYK 90
Cdd:COG1620    2 SLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGL-PILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  91 IATESGQFNIVQDSIASISQDQRIQLLLIGYLFNGFLEGAAGFGVPIAICAVLLMQLGFKALPAAMYCLVANAAAGAYGA 170
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 171 VGIPIAitdTLNLAGGVKASQVALIGNLTLGLISFFVPFLLMFIIDGLKGVKETFPATLIAASVFTGLQVLIAAFAGPEL 250
Cdd:COG1620  161 VGTPII---VGAQVTGLDALEIGAMVGRQLPILSLLIPFLLVWILDGWRGIKEVWPAALVAGLSFAVPQFLTANFLGPEL 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 251 ADIIPGLGAMVALALFSRKFQPKNIFRLEDNEAVGK----VEKHSIKQIVYGWSPFIILTVIVMVWSL-PAFKALfekgg 325
Cdd:COG1620  238 PDIIAGLVGLAALVLFLRFWKPKEIWDFAPEEEWPAeeedAEKLSAMSLLKAWSPYLLLIVLLVLTRLpPPVKAL----- 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 326 aLSALVVNFNAPGTMNNVTHHpNVLTFNFIAQTGTAILVTAIITILIAKhMSFKTAGKLLGVTVKELWVSVLTICFILAV 405
Cdd:COG1620  313 -LNSTTLKIPWPGLLGAGTTG-ASYSFNPLYAPGTAILLAALITILLLR-MSPGQAKRAFKETLKQLRGPILTLAFVLAL 389
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 406 SKITTYGGLSNAMGQGIA-KTGAIFPLLSPVLGWIGVFMTGSVVNNNSLFAPIQASVATQIGTKGSLLVAANVAGGVTAK 484
Cdd:COG1620  390 AYVMNYSGMPATLGLALAaATGAAFPFFAPFLGWLGVFITGSDTSSNALFGGLQFTTAEQLGLSPTLIVAAQSVGGVMGK 469
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*....
gi 488409182 485 IVSPQSIAIATAAVNKVGKESELMKMAMRFSIGLLIFACIWTFMLSLFV 533
Cdd:COG1620  470 MISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
Lactate_perm pfam02652
L-lactate permease; L-lactate permease is an integral membrane protein probably involved in ...
14-529 1.66e-133

L-lactate permease; L-lactate permease is an integral membrane protein probably involved in L-lactate transport.


Pssm-ID: 280762  Cd Length: 522  Bit Score: 397.90  E-value: 1.66e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   14 ISAIVAAVPIILFLLCLTVFKMKGVYAALTTLIVTALVAMICFKLPARIAGGATFEGFYQGIIPIGFIVIMAVWLYKIAT 93
Cdd:pfam02652   1 LSALVALTPILLFFFLLAVLKMKGYYAAPISLAVTVIIALLYYKMPVENTISSVLYGALYGLWPIAWIIIAAIFLYKISV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   94 ESGQFNIVQDSIASISQDQRIQLLLIGYLFNGFLEGAAGFGVPIAICAVLLMQLGFKALPAAMYCLVANAAAGAYGAVGI 173
Cdd:pfam02652  81 KSGAFEIIRSSILNISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAVGI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  174 PIAitdTLNLAGGVKASQVALIGNLTLGLISFFVPFLLMFIIDGLKGVKETFPATLIAASVFTGLQVLIAAFAGPELADI 253
Cdd:pfam02652 161 PIT---AGAGATGLSALEISSMVGFQLPFISLLIPFFLVFLMDGFKGIKETFPAVLVSGLSFAIPQFLSSNVLGPELPSI 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  254 IPGLGAMVALALFSRKFQPKNIFRLEDNEAVGKVEKHSIKQIVYGWSPFIILTVIVMVWSLPAFKALFEKGGALSALVVN 333
Cdd:pfam02652 238 LGALVSLVITALFLKFWQPKEIFRFAGKGDSGATSALRAGKIVKAWSPFVLLTAFIVLWSIPQFKALFQEGGALYTSTFN 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  334 ----------FNAPGTMNNVTHHPNVLTFNFIAQTGTAILVTAIITILIAKhMSFKTAGKLLGVTVKELWVSVLTICFIL 403
Cdd:pfam02652 318 fefpeisqliFSIPPIVGEATPFPVVFKFKLLYSPGTIIFLAALLSIFILK-VSSSDALSIFKETLKEMALPIITIIFVL 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  404 AVSKITTYGGLSNAMGQGIAKTGAIFPLLSPVLGWIGVFMTGSVVNNNSLFAPIQASVATQIGTKGSLLVAANVAGGVTA 483
Cdd:pfam02652 397 AFANLMNYSGMSKTLALALAHTGSAFTFFSPFLGWLGVFLTGSDTSSNLLFGSLQLVTAEQIGLPPVLLLAANTVGGVMG 476
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 488409182  484 KIVSPQSIAIATAAVNKVGKESELMKMAMRFSIGLLIFACIWTFML 529
Cdd:pfam02652 477 KMISPQSIAIACAAVGLAGKESDLFRKTIKYSLIYAIIVGVVAFLL 522
PRK10420 PRK10420
L-lactate permease; Provisional
4-524 4.67e-131

L-lactate permease; Provisional


Pssm-ID: 182445  Cd Length: 551  Bit Score: 392.67  E-value: 4.67e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   4 ESFNPFNNMLISAIVAAVPIILFLLCLTVFKMKGVYAALTTLIVTALVAMICFKLPARIAGGATFEGFYQGIIPIGFIVI 83
Cdd:PRK10420   6 QNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIII 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  84 MAVWLYKIATESGQFNIVQDSIASISQDQRIQLLLIGYLFNGFLEGAAGFGVPIAICAVLLMQLGFKALPAAMYCLVANA 163
Cdd:PRK10420  86 AAVFVYKISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLIVNT 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 164 AAGAYGAVGIPIAITDTLNlagGVKASQVALIGNLTLGLISFFVPFLLMFIIDGLKGVKETFPATLIAASVFTGLQVLIA 243
Cdd:PRK10420 166 APVAFGAMGIPILVAGQVT---GIDSFEIGQMVGRQLPFLTIIVLFWIMAIMDGWRGVKETWPAVVVAGGSFAIAQYLSS 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 244 AFAGPELADIIPGLGAMVALALFSRKFQPKNIFRLEDNEAVG-----KVEKHSIKQIVYGWSPFIILTVIVMVWSLPAFK 318
Cdd:PRK10420 243 NFIGPELPDIISSLVSLVCLTLFLKRWQPVRIFRFGDLGASQvdmtlAHTGYTAGQVLRAWSPFLFLTATVTLWSIPPFK 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 319 ALFEKGGALSALVVNFNAPGTMNNVTHHPNVL----------TFNFIAQTGTAILVTAIITILIAKhMSFKTAGKLLGVT 388
Cdd:PRK10420 323 ALFASGGALYEWVINIPVPYLDKLVARMPPVVseatayaavyKFDWFSATGTAILFAALLSIVWLK-MKPSDAISTFGST 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 389 VKELWVSVLTICFILAVSKITTYGGLSNAMGQGIAKTGAIFPLLSPVLGWIGVFMTGSVVNNNSLFAPIQASVATQIGTK 468
Cdd:PRK10420 402 LKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLGWLGVFLTGSDTSSNALFAALQATAAQQIGVS 481
                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 488409182 469 GSLLVAANVAGGVTAKIVSPQSIAIATAAVNKVGKESELMKMAMRFSiglLIFACI 524
Cdd:PRK10420 482 DVLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHS---LIFTCM 534
lctP TIGR00795
L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized ...
12-529 1.05e-130

L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized member of this family, from E. coli, appears to catalyze lactate:H+ uptake. Members of this family have 12 probable TMS. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 162041  Cd Length: 530  Bit Score: 390.98  E-value: 1.05e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   12 MLISAIVAAVPIILFLLCLTVFKMKGVYAALTTLIVTALVAMICFKLPARIAGGATFEGFYQGIIPIGFIVIMAVWLYKI 91
Cdd:TIGR00795   5 DWLSAIVALLPILLFFFLLAVLKLKGYYAAPISVALSVIIALFYYKMPVIMTSAAFLYGFLYGLWPIAWIIIAAIFLYKL 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   92 ATESGQFNIVQDSIASISQDQRIQLLLIGYLFNGFLEGAAGFGVPIAICAVLLMQLGFKALPAAMYCLVANAAAGAYGAV 171
Cdd:TIGR00795  85 SVKSGAFEIIRSSILSISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAV 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  172 GIPIAitdTLNLAGGVKASQVALIGNLTLGLISFFVPFLLMFIIDGLKGVKETFPATLIAASVFTGLQVLIAAFAGPELA 251
Cdd:TIGR00795 165 GIPIW---AGAQATGLSALEISSMTGFQLPFISLLIPFFLVFLMDGWKGIKETFPAVLVAGLSFAIPQFLSSNYLGPELP 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  252 DIIPGLGAMVALALFSRKFQPKNIFRLEDNEAVGKVEKHSIKQIVYGWSPFIILTVIVMVWSLPAFKALFEKGGALSALV 331
Cdd:TIGR00795 242 SILGALVSLVITALFLKFWQPKEIFRFNGKLDAGEVSAHHICKIVKAWSPFVLLTAFIVLWSIPPFKALFMKGGALIFSS 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  332 VNFNAPGTMNNV----------THHPNVLTFNFIAQTGTAILVTAIITILIAKhMSFKTAGKLLGVTVKELWVSVLTICF 401
Cdd:TIGR00795 322 FTFGSPGLSQHIfklppivnqaTNFPAVFKLLLIIATGTSILLAAIVSFFILR-VSISDAIGVFGETLKEMRLPILTIGM 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  402 ILAVSKITTYGGLSNAMGQGIAKTGAIFPLLSPVLGWIGVFMTGSVVNNNSLFAPIQASVATQIGTKGSLLVAANVAGGV 481
Cdd:TIGR00795 401 VLAFANVSNYSGMSKTLALALAHTGLAFTFFSPFLGWLGVFLTGSDTSSNLLFGSLQLLTAEQIGLPETLLLAANTVGGV 480
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 488409182  482 TAKIVSPQSIAIATAAVNKVGKESELMKMAMRFSIGLLIFACIWTFML 529
Cdd:TIGR00795 481 MGKMISPQSIAIACAAVGLVGQESDLFRKTVKYSLIYAIIVGVVALLL 528
PRK09695 PRK09695
glycolate permease GlcA;
4-524 7.14e-102

glycolate permease GlcA;


Pssm-ID: 182032  Cd Length: 560  Bit Score: 317.77  E-value: 7.14e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182   4 ESFNPFNNMLISAIVAAVPIILFLLCLTVFKMKGVYAALTTLIVTALVAMICFKLPARIAGGATFEGFYQGIIPIGFIVI 83
Cdd:PRK09695   6 QMYMPMGGLGLSALVALIPIIFFFVALAVLRLKGHVAGAITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLWPIAWIIV 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182  84 MAVWLYKIATESGQFNIVQDSIASISQDQRIQLLLIGYLFNGFLEGAAGFGVPIAICAVLLMQLGFKALPAAMYCLVANA 163
Cdd:PRK09695  86 AAVFLYKLTVASGQFDIIRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLCLIANT 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 164 AAGAYGAVGIPIAITDTLNlagGVKASQVALIGNLTLGLISFFVPFLLMFIIDGLKGVKETFPATLIAASVFTGLQVLIA 243
Cdd:PRK09695 166 APVAFGALGVPILVAGQVT---GIDPFHIGAMAGRQLPFLSVLVPFWLVAMMDGWKGVKETWPAALVAGGSFAVTQFFTS 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 244 AFAGPELADIIPGLGAMVALALFSRKFQPKNI-FRLEDNEAVGKV------------EKHSIKQIVYGWSPFIILTVIVM 310
Cdd:PRK09695 243 NYIGPELPDITSALVSIVSLALFLKVWRPKNTeTAISMGQSAGAMvvnkpssggpvpSEYSLGQIIRAWSPFLILTVLVT 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 311 VWSLPAFKALFEKGGALSALVVNFNAPGTMNNV----------THHPNVLTFNFIAQTGTAILVTAIITILIAKhMSFKT 380
Cdd:PRK09695 323 IWTMKPFKALFAPGGAFYSLVINFQIPHLHQQVlkaapivaqpTPMDAVFKFDPLSAGGTAIFIAAIISIFILG-VGIKK 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488409182 381 AGKLLGVTVKELWVSVLTICFILAVSKITTYGGLSNAMGQGIAKTGAIFPLLSPVLGWIGVFMTGSVVNNNSLFAPIQAS 460
Cdd:PRK09695 402 GIGVFAETLISLKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGVMFPFFSPFLGWLGVFLTGSDTSSNALFGSLQST 481
                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488409182 461 VATQIGTKGSLLVAANVAGGVTAKIVSPQSIAIATAAVNKVGKESELMKMAMRFSiglLIFACI 524
Cdd:PRK09695 482 TAQQINVSDTLLVAANTSGGVTGKMISPQSIAVACAATGMVGRESELFRYTVKHS---LIFASV 542
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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