malate:quinone oxidoreductase catalyzes the oxidation of malate to oxaloacetate using quinone as the electron acceptor as part of the citric acid cycle
L-lactate dehydrogenase (quinone), SACOL2623 family; Members of this family, found primarily ...
7-495
0e+00
L-lactate dehydrogenase (quinone), SACOL2623 family; Members of this family, found primarily in the genus Streptococcus, were shown to be L-lactate dehydrogenase (quinone) (Lqo) although they have generally been misannotated as malate dehydrogenase (quinone). Staphylococcus can survive nitrous oxide exposure from host defense through a response in which L-lactate is excreted in large amounts. Lqo acts in L-lactate consumption after its reuptake.
:
Pssm-ID: 468783 Cd Length: 489 Bit Score: 1091.00 E-value: 0e+00
L-lactate dehydrogenase (quinone), SACOL2623 family; Members of this family, found primarily ...
7-495
0e+00
L-lactate dehydrogenase (quinone), SACOL2623 family; Members of this family, found primarily in the genus Streptococcus, were shown to be L-lactate dehydrogenase (quinone) (Lqo) although they have generally been misannotated as malate dehydrogenase (quinone). Staphylococcus can survive nitrous oxide exposure from host defense through a response in which L-lactate is excreted in large amounts. Lqo acts in L-lactate consumption after its reuptake.
Pssm-ID: 468783 Cd Length: 489 Bit Score: 1091.00 E-value: 0e+00
Malate:quinone oxidoreductase (Mqo); This family consists of several bacterial Malate:quinone ...
6-492
0e+00
Malate:quinone oxidoreductase (Mqo); This family consists of several bacterial Malate:quinone oxidoreductase (Mqo) proteins (EC:1.1.99.16). Mqo takes part in the citric acid cycle. It oxidizes L-malate to oxaloacetate and donates electrons to ubiquinone-1 and other artificial acceptors or, via the electron transfer chain, to oxygen. NAD is not an acceptor and the natural direct acceptor for the enzyme is most likely a quinone. The enzyme is therefore called malate:quinone oxidoreductase, abbreviated to Mqo. Mqo is a peripheral membrane protein and can be released from the membrane by addition of chelators.
Pssm-ID: 461809 Cd Length: 488 Bit Score: 895.65 E-value: 0e+00
malate:quinone-oxidoreductase; This membrane-associated enzyme is an alternative to the ...
8-490
0e+00
malate:quinone-oxidoreductase; This membrane-associated enzyme is an alternative to the better-known NAD-dependent malate dehydrogenase as part of the TCA cycle. The reduction of a quinone rather than NAD+ makes the reaction essentially irreversible in the direction of malate oxidation to oxaloacetate. Both forms of malate dehydrogenase are active in E. coli; disruption of this form causes less phenotypic change. In some bacteria, this form is the only or the more important malate dehydrogenase. [Energy metabolism, TCA cycle]
Pssm-ID: 130387 Cd Length: 483 Bit Score: 629.94 E-value: 0e+00
L-lactate dehydrogenase (quinone), SACOL2623 family; Members of this family, found primarily ...
7-495
0e+00
L-lactate dehydrogenase (quinone), SACOL2623 family; Members of this family, found primarily in the genus Streptococcus, were shown to be L-lactate dehydrogenase (quinone) (Lqo) although they have generally been misannotated as malate dehydrogenase (quinone). Staphylococcus can survive nitrous oxide exposure from host defense through a response in which L-lactate is excreted in large amounts. Lqo acts in L-lactate consumption after its reuptake.
Pssm-ID: 468783 Cd Length: 489 Bit Score: 1091.00 E-value: 0e+00
Malate:quinone oxidoreductase (Mqo); This family consists of several bacterial Malate:quinone ...
6-492
0e+00
Malate:quinone oxidoreductase (Mqo); This family consists of several bacterial Malate:quinone oxidoreductase (Mqo) proteins (EC:1.1.99.16). Mqo takes part in the citric acid cycle. It oxidizes L-malate to oxaloacetate and donates electrons to ubiquinone-1 and other artificial acceptors or, via the electron transfer chain, to oxygen. NAD is not an acceptor and the natural direct acceptor for the enzyme is most likely a quinone. The enzyme is therefore called malate:quinone oxidoreductase, abbreviated to Mqo. Mqo is a peripheral membrane protein and can be released from the membrane by addition of chelators.
Pssm-ID: 461809 Cd Length: 488 Bit Score: 895.65 E-value: 0e+00
malate:quinone-oxidoreductase; This membrane-associated enzyme is an alternative to the ...
8-490
0e+00
malate:quinone-oxidoreductase; This membrane-associated enzyme is an alternative to the better-known NAD-dependent malate dehydrogenase as part of the TCA cycle. The reduction of a quinone rather than NAD+ makes the reaction essentially irreversible in the direction of malate oxidation to oxaloacetate. Both forms of malate dehydrogenase are active in E. coli; disruption of this form causes less phenotypic change. In some bacteria, this form is the only or the more important malate dehydrogenase. [Energy metabolism, TCA cycle]
Pssm-ID: 130387 Cd Length: 483 Bit Score: 629.94 E-value: 0e+00
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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