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Conserved domains on  [gi|488384083|ref|WP_002453468|]
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MULTISPECIES: DUF948 domain-containing protein [Staphylococcus]

Protein Classification

DUF948 domain-containing protein( domain architecture ID 10008827)

uncharacterized DUF948 domain-containing protein similar to Bacillus subtilis YtxG, may be involved in stress response

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4768 COG4768
Uncharacterized conserved protein YoxC, contains an MCP-like domain [Function unknown];
17-134 3.96e-48

Uncharacterized conserved protein YoxC, contains an MCP-like domain [Function unknown];


:

Pssm-ID: 443800 [Multi-domain]  Cd Length: 132  Bit Score: 152.70  E-value: 3.96e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488384083  17 LILCIGIVVVLISVKKNLDYVAKTLDGVEGQVQGITRETTDLLHKANRLTEDIQGKVDRLNSVVDAVKGIGDSVQTLNGS 96
Cdd:COG4768   15 LVLVIYLVKTLKKVKKTLNEVNKTLEGLEKQLDGITTETTDLLHKTNRLAEDVNGKVEKLDPLFDAVKDVGESVSDLNSS 94

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 488384083  97 VDRVTNSITHNISQNEDKISQVVQWSNVAMEIADKWQN 134
Cdd:COG4768   95 LRDVTSSVSSKVEKNSEKVAQVVKWGKVALGLFKKKKK 132
 
Name Accession Description Interval E-value
COG4768 COG4768
Uncharacterized conserved protein YoxC, contains an MCP-like domain [Function unknown];
17-134 3.96e-48

Uncharacterized conserved protein YoxC, contains an MCP-like domain [Function unknown];


Pssm-ID: 443800 [Multi-domain]  Cd Length: 132  Bit Score: 152.70  E-value: 3.96e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488384083  17 LILCIGIVVVLISVKKNLDYVAKTLDGVEGQVQGITRETTDLLHKANRLTEDIQGKVDRLNSVVDAVKGIGDSVQTLNGS 96
Cdd:COG4768   15 LVLVIYLVKTLKKVKKTLNEVNKTLEGLEKQLDGITTETTDLLHKTNRLAEDVNGKVEKLDPLFDAVKDVGESVSDLNSS 94

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 488384083  97 VDRVTNSITHNISQNEDKISQVVQWSNVAMEIADKWQN 134
Cdd:COG4768   95 LRDVTSSVSSKVEKNSEKVAQVVKWGKVALGLFKKKKK 132
DUF948 pfam06103
Bacterial protein of unknown function (DUF948); This family consists of bacterial sequences ...
 13-89 1.14e-19

Bacterial protein of unknown function (DUF948); This family consists of bacterial sequences several of which are thought to be general stress proteins.


Pssm-ID: 428770 [Multi-domain]  Cd Length: 83  Bit Score: 78.34  E-value: 1.14e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488384083   13 AIAFLILCIGIVVVLISVKKNLDYVAKTLDGVEGQVQGITRETTDLLHKANRLTEDIQGKVDRLNSVVDAVKGIGDS 89
Cdd:pfam06103   7 AIAFVVLVIFLIPTLKKLGKTLDEVRKTIEGLEKQVDPILKETTDLLAKTNELLEDVNGKLEKVDPVFEAVADLGES 83
Mtu_fam_mce TIGR00996
virulence factor Mce family protein; Members of this paralogous family are found as six tandem ...
 34-130 1.29e-03

virulence factor Mce family protein; Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis]


Pssm-ID: 273384 [Multi-domain]  Cd Length: 291  Bit Score: 38.04  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488384083   34 LDYVAKTLDGVEGQVQGITRETTDLLHKANRLTEDIQGKVDRLNSVVDAVkgiGDSVQTLNGSVDRVtNSITHNISQNED 113
Cdd:TIGR00996 155 LNALAQALAGQGPQLRNLLDGLAQLTAALNERDGDIGELIRNLNRVLDVL---ADRSDQLDRLLDNL-PTLIATLADRSD 230

                          90
                  ....*....|....*...
gi 488384083  114 KISQVV-QWSNVAMEIAD 130
Cdd:TIGR00996 231 ALDDALaALSAASAQVRD 248
 
Name Accession Description Interval E-value
COG4768 COG4768
Uncharacterized conserved protein YoxC, contains an MCP-like domain [Function unknown];
17-134 3.96e-48

Uncharacterized conserved protein YoxC, contains an MCP-like domain [Function unknown];


Pssm-ID: 443800 [Multi-domain]  Cd Length: 132  Bit Score: 152.70  E-value: 3.96e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488384083  17 LILCIGIVVVLISVKKNLDYVAKTLDGVEGQVQGITRETTDLLHKANRLTEDIQGKVDRLNSVVDAVKGIGDSVQTLNGS 96
Cdd:COG4768   15 LVLVIYLVKTLKKVKKTLNEVNKTLEGLEKQLDGITTETTDLLHKTNRLAEDVNGKVEKLDPLFDAVKDVGESVSDLNSS 94

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 488384083  97 VDRVTNSITHNISQNEDKISQVVQWSNVAMEIADKWQN 134
Cdd:COG4768   95 LRDVTSSVSSKVEKNSEKVAQVVKWGKVALGLFKKKKK 132
DUF948 pfam06103
Bacterial protein of unknown function (DUF948); This family consists of bacterial sequences ...
 13-89 1.14e-19

Bacterial protein of unknown function (DUF948); This family consists of bacterial sequences several of which are thought to be general stress proteins.


Pssm-ID: 428770 [Multi-domain]  Cd Length: 83  Bit Score: 78.34  E-value: 1.14e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488384083   13 AIAFLILCIGIVVVLISVKKNLDYVAKTLDGVEGQVQGITRETTDLLHKANRLTEDIQGKVDRLNSVVDAVKGIGDS 89
Cdd:pfam06103   7 AIAFVVLVIFLIPTLKKLGKTLDEVRKTIEGLEKQVDPILKETTDLLAKTNELLEDVNGKLEKVDPVFEAVADLGES 83
Mtu_fam_mce TIGR00996
virulence factor Mce family protein; Members of this paralogous family are found as six tandem ...
 34-130 1.29e-03

virulence factor Mce family protein; Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis]


Pssm-ID: 273384 [Multi-domain]  Cd Length: 291  Bit Score: 38.04  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488384083   34 LDYVAKTLDGVEGQVQGITRETTDLLHKANRLTEDIQGKVDRLNSVVDAVkgiGDSVQTLNGSVDRVtNSITHNISQNED 113
Cdd:TIGR00996 155 LNALAQALAGQGPQLRNLLDGLAQLTAALNERDGDIGELIRNLNRVLDVL---ADRSDQLDRLLDNL-PTLIATLADRSD 230

                          90
                  ....*....|....*...
gi 488384083  114 KISQVV-QWSNVAMEIAD 130
Cdd:TIGR00996 231 ALDDALaALSAASAQVRD 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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