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Conserved domains on  [gi|488363483|ref|WP_002432868|]
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AraC family transcriptional regulator Rsp [Staphylococcus capitis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
viru_reg_Rsp NF033869
AraC family transcriptional regulator Rsp; Rsp (repressor of surface proteins), as described ...
 1-701 0e+00

AraC family transcriptional regulator Rsp; Rsp (repressor of surface proteins), as described in Staphylococcus aureus, is a large protein with an AraC-like helix-turn-helix DNA-binding domain. Regulatory targets include the accessory gene regulator (agr) operon, which in turn regulates a large number of virulence factors.


:

Pssm-ID: 411433 [Multi-domain]  Cd Length: 701  Bit Score: 1235.36  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483   1 MTCHLNIYQQYHSPPTRNINRIILMFSLTNHLEITINGETKDLDNHIAIINQADIFYVNQSSNLVMPSIPVFYFYSEDEN 80
Cdd:NF033869   1 MTCTLNIHEQLSTAPSRNINQIIILFSLTNELRITINGETKDLDNHIAIINHGDIYNINQGSNLVELSIPVFYFYIEDND 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483  81 FFKCYFDRHLLQSSGFVKNIILQSIHHYMNEEEQDTQAISKIIQTLFKETVIRYKEKYIPQVAINHPIFIQGLSYIHSKV 160
Cdd:NF033869  81 FFNCYFDRHLLQSSHYIKSLILQLIHHDSNNEEQDDQVISKIIQTLYKEAVVRHPHLYIPNIAVNNPVFINCLTFIHDHI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 161 SDTLSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLLSTDDSINAISERSGFSSHTNFTNQFKNHLGF 240
Cdd:NF033869 161 SSNLSLRDVAQHCNISESYCSNLFVRYLNMNFKDYFTSLKLCHAIQLLLSTNHSINAISELSGFSSHTNFTNQFKNYLNF 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 241 SPKQFRSMISKISLNPVMDFSQTHFWDYKDLINQFEFNDQLATEITEIDLNQFNPKDHTKSSKAFIRFENFNKLFQFVFN 320
Cdd:NF033869 241 SPKQFRTLLSKIDPLPQIHFSSDIVAQFLELISQFEFTDQLATETTEIDIDHFNPKDHTQRSKAFIRFNNFNELFQFVFN 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 321 EYYDIDFSYLPQPVVFIQDINDIAISHINLNLLNRCFEKLFEMDIGLAMQINSTQQFEAINQIILSFLQSNQDYKNNKKL 400
Cdd:NF033869 321 EYYDIDLSYLPKPVILINDISDIEMSQINYNLLNRCFEKLFEKNIGLAMTIKSTQQFETIYQLILTFLQNNQDYKKNKKL 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 401 VKLMLVFNSEYMTVNEIHLCHLKIKNKNREIRYGITVEGLLRDSPSIDQTYDIMKRLNFDYYFIDIENLETKNLLLTKRK 480
Cdd:NF033869 401 VKFMLVFDSESMTIHDIHLCHLKIKNKNRNIKYGVTVDGLLHQYSTLQETYDIMKRLNFDYYFIDIENIETKNLLITKSK 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 481 TYHHSSTHFENYKQFMLDSGIPTTNFVYNNLSLKCFKYTNNGTNPLQLSDLVCHLIALMRYGGGISYQLIDDHSQYIALF 560
Cdd:NF033869 481 GFTHTSTHFENYKQFILDSGIPSTKFVYNNLSLKCFKYTNNGTNPLQLSDLVCHLIALLRYGGGISYQLIEDDSMYISLF 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 561 NNYGSPLPLMHIYKMGDSFVDEPLELGNNYLISRKDGNYHILLFNKINDRYLSDSKQKFIFKNNLKKNSLIIIKTLNNEH 640
Cdd:NF033869 561 NKYGSPLPLMHLYKMVAAFVNEPIEITNNYLMSRKDGNYHFLLFNKINDRYLSDSKQHFIFKNNLKENSLIIVKTLNHEH 640

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488363483 641 GSIQNLLPKSKELLYIERNILEELDKCNRPKTELAIQEENNKPFQMTLKHDEVKYICFKPI 701
Cdd:NF033869 641 GSIQNLLPQDKQLVYIEKEILDQLDRSNYPKTELAIQEEDNKTFEITLKHDEVKYICIKPS 701
 
Name Accession Description Interval E-value
viru_reg_Rsp NF033869
AraC family transcriptional regulator Rsp; Rsp (repressor of surface proteins), as described ...
 1-701 0e+00

AraC family transcriptional regulator Rsp; Rsp (repressor of surface proteins), as described in Staphylococcus aureus, is a large protein with an AraC-like helix-turn-helix DNA-binding domain. Regulatory targets include the accessory gene regulator (agr) operon, which in turn regulates a large number of virulence factors.


Pssm-ID: 411433 [Multi-domain]  Cd Length: 701  Bit Score: 1235.36  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483   1 MTCHLNIYQQYHSPPTRNINRIILMFSLTNHLEITINGETKDLDNHIAIINQADIFYVNQSSNLVMPSIPVFYFYSEDEN 80
Cdd:NF033869   1 MTCTLNIHEQLSTAPSRNINQIIILFSLTNELRITINGETKDLDNHIAIINHGDIYNINQGSNLVELSIPVFYFYIEDND 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483  81 FFKCYFDRHLLQSSGFVKNIILQSIHHYMNEEEQDTQAISKIIQTLFKETVIRYKEKYIPQVAINHPIFIQGLSYIHSKV 160
Cdd:NF033869  81 FFNCYFDRHLLQSSHYIKSLILQLIHHDSNNEEQDDQVISKIIQTLYKEAVVRHPHLYIPNIAVNNPVFINCLTFIHDHI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 161 SDTLSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLLSTDDSINAISERSGFSSHTNFTNQFKNHLGF 240
Cdd:NF033869 161 SSNLSLRDVAQHCNISESYCSNLFVRYLNMNFKDYFTSLKLCHAIQLLLSTNHSINAISELSGFSSHTNFTNQFKNYLNF 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 241 SPKQFRSMISKISLNPVMDFSQTHFWDYKDLINQFEFNDQLATEITEIDLNQFNPKDHTKSSKAFIRFENFNKLFQFVFN 320
Cdd:NF033869 241 SPKQFRTLLSKIDPLPQIHFSSDIVAQFLELISQFEFTDQLATETTEIDIDHFNPKDHTQRSKAFIRFNNFNELFQFVFN 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 321 EYYDIDFSYLPQPVVFIQDINDIAISHINLNLLNRCFEKLFEMDIGLAMQINSTQQFEAINQIILSFLQSNQDYKNNKKL 400
Cdd:NF033869 321 EYYDIDLSYLPKPVILINDISDIEMSQINYNLLNRCFEKLFEKNIGLAMTIKSTQQFETIYQLILTFLQNNQDYKKNKKL 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 401 VKLMLVFNSEYMTVNEIHLCHLKIKNKNREIRYGITVEGLLRDSPSIDQTYDIMKRLNFDYYFIDIENLETKNLLLTKRK 480
Cdd:NF033869 401 VKFMLVFDSESMTIHDIHLCHLKIKNKNRNIKYGVTVDGLLHQYSTLQETYDIMKRLNFDYYFIDIENIETKNLLITKSK 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 481 TYHHSSTHFENYKQFMLDSGIPTTNFVYNNLSLKCFKYTNNGTNPLQLSDLVCHLIALMRYGGGISYQLIDDHSQYIALF 560
Cdd:NF033869 481 GFTHTSTHFENYKQFILDSGIPSTKFVYNNLSLKCFKYTNNGTNPLQLSDLVCHLIALLRYGGGISYQLIEDDSMYISLF 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 561 NNYGSPLPLMHIYKMGDSFVDEPLELGNNYLISRKDGNYHILLFNKINDRYLSDSKQKFIFKNNLKKNSLIIIKTLNNEH 640
Cdd:NF033869 561 NKYGSPLPLMHLYKMVAAFVNEPIEITNNYLMSRKDGNYHFLLFNKINDRYLSDSKQHFIFKNNLKENSLIIVKTLNHEH 640

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488363483 641 GSIQNLLPKSKELLYIERNILEELDKCNRPKTELAIQEENNKPFQMTLKHDEVKYICFKPI 701
Cdd:NF033869 641 GSIQNLLPQDKQLVYIEKEILDQLDRSNYPKTELAIQEEDNKTFEITLKHDEVKYICIKPS 701
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
164-253 1.06e-20

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.15  E-value: 1.06e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 164 LSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLLSTDDSINAISERSGFSSHTNFTNQFKNHLGFSPK 243
Cdd:COG2207  169 LTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPS 248

                         90
                 ....*....|
gi 488363483 244 QFRSMISKIS 253
Cdd:COG2207  249 EYRKRLRARA 258
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
164-246 1.80e-20

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 86.07  E-value: 1.80e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483   164 LSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLLSTDDSINAISERSGFSSHTNFTNQFKNHLGFSPK 243
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 488363483   244 QFR 246
Cdd:smart00342  82 EYR 84
HTH_18 pfam12833
Helix-turn-helix domain;
169-246 3.60e-16

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 73.78  E-value: 3.60e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488363483  169 VANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLL-STDDSINAISERSGFSSHTNFTNQFKNHLGFSPKQFR 246
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLeDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYR 79
PRK10371 PRK10371
transcriptional regulator MelR;
128-246 7.05e-12

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 66.77  E-value: 7.05e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 128 KETVIRYKEKYIPQVainhpifiqgLSYIHSKVSDTLSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKL 207
Cdd:PRK10371 182 KNSVSRHAQFYVSQM----------LGFIAENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRAL 251

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 488363483 208 LLSTDDSINAISERSGFSSHTNFTNQFKNHLGFSPKQFR 246
Cdd:PRK10371 252 LSDTDKSILDIALTAGFRSSSRFYSTFGKYVGMSPQQYR 290
 
Name Accession Description Interval E-value
viru_reg_Rsp NF033869
AraC family transcriptional regulator Rsp; Rsp (repressor of surface proteins), as described ...
 1-701 0e+00

AraC family transcriptional regulator Rsp; Rsp (repressor of surface proteins), as described in Staphylococcus aureus, is a large protein with an AraC-like helix-turn-helix DNA-binding domain. Regulatory targets include the accessory gene regulator (agr) operon, which in turn regulates a large number of virulence factors.


Pssm-ID: 411433 [Multi-domain]  Cd Length: 701  Bit Score: 1235.36  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483   1 MTCHLNIYQQYHSPPTRNINRIILMFSLTNHLEITINGETKDLDNHIAIINQADIFYVNQSSNLVMPSIPVFYFYSEDEN 80
Cdd:NF033869   1 MTCTLNIHEQLSTAPSRNINQIIILFSLTNELRITINGETKDLDNHIAIINHGDIYNINQGSNLVELSIPVFYFYIEDND 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483  81 FFKCYFDRHLLQSSGFVKNIILQSIHHYMNEEEQDTQAISKIIQTLFKETVIRYKEKYIPQVAINHPIFIQGLSYIHSKV 160
Cdd:NF033869  81 FFNCYFDRHLLQSSHYIKSLILQLIHHDSNNEEQDDQVISKIIQTLYKEAVVRHPHLYIPNIAVNNPVFINCLTFIHDHI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 161 SDTLSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLLSTDDSINAISERSGFSSHTNFTNQFKNHLGF 240
Cdd:NF033869 161 SSNLSLRDVAQHCNISESYCSNLFVRYLNMNFKDYFTSLKLCHAIQLLLSTNHSINAISELSGFSSHTNFTNQFKNYLNF 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 241 SPKQFRSMISKISLNPVMDFSQTHFWDYKDLINQFEFNDQLATEITEIDLNQFNPKDHTKSSKAFIRFENFNKLFQFVFN 320
Cdd:NF033869 241 SPKQFRTLLSKIDPLPQIHFSSDIVAQFLELISQFEFTDQLATETTEIDIDHFNPKDHTQRSKAFIRFNNFNELFQFVFN 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 321 EYYDIDFSYLPQPVVFIQDINDIAISHINLNLLNRCFEKLFEMDIGLAMQINSTQQFEAINQIILSFLQSNQDYKNNKKL 400
Cdd:NF033869 321 EYYDIDLSYLPKPVILINDISDIEMSQINYNLLNRCFEKLFEKNIGLAMTIKSTQQFETIYQLILTFLQNNQDYKKNKKL 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 401 VKLMLVFNSEYMTVNEIHLCHLKIKNKNREIRYGITVEGLLRDSPSIDQTYDIMKRLNFDYYFIDIENLETKNLLLTKRK 480
Cdd:NF033869 401 VKFMLVFDSESMTIHDIHLCHLKIKNKNRNIKYGVTVDGLLHQYSTLQETYDIMKRLNFDYYFIDIENIETKNLLITKSK 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 481 TYHHSSTHFENYKQFMLDSGIPTTNFVYNNLSLKCFKYTNNGTNPLQLSDLVCHLIALMRYGGGISYQLIDDHSQYIALF 560
Cdd:NF033869 481 GFTHTSTHFENYKQFILDSGIPSTKFVYNNLSLKCFKYTNNGTNPLQLSDLVCHLIALLRYGGGISYQLIEDDSMYISLF 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 561 NNYGSPLPLMHIYKMGDSFVDEPLELGNNYLISRKDGNYHILLFNKINDRYLSDSKQKFIFKNNLKKNSLIIIKTLNNEH 640
Cdd:NF033869 561 NKYGSPLPLMHLYKMVAAFVNEPIEITNNYLMSRKDGNYHFLLFNKINDRYLSDSKQHFIFKNNLKENSLIIVKTLNHEH 640

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488363483 641 GSIQNLLPKSKELLYIERNILEELDKCNRPKTELAIQEENNKPFQMTLKHDEVKYICFKPI 701
Cdd:NF033869 641 GSIQNLLPQDKQLVYIEKEILDQLDRSNYPKTELAIQEEDNKTFEITLKHDEVKYICIKPS 701
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
164-253 1.06e-20

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.15  E-value: 1.06e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 164 LSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLLSTDDSINAISERSGFSSHTNFTNQFKNHLGFSPK 243
Cdd:COG2207  169 LTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPS 248

                         90
                 ....*....|
gi 488363483 244 QFRSMISKIS 253
Cdd:COG2207  249 EYRKRLRARA 258
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
164-246 1.80e-20

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 86.07  E-value: 1.80e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483   164 LSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLLSTDDSINAISERSGFSSHTNFTNQFKNHLGFSPK 243
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 488363483   244 QFR 246
Cdd:smart00342  82 EYR 84
HTH_18 pfam12833
Helix-turn-helix domain;
169-246 3.60e-16

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 73.78  E-value: 3.60e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488363483  169 VANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLL-STDDSINAISERSGFSSHTNFTNQFKNHLGFSPKQFR 246
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLeDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYR 79
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 140-246 1.25e-12

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 69.42  E-value: 1.25e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 140 PQVAINHPIFIQGLSYIHSKVSDTLSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLLSTDDSINAIS 219
Cdd:COG4977  203 VPLGHRDPRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIA 282

                         90       100
                 ....*....|....*....|....*..
gi 488363483 220 ERSGFSSHTNFTNQFKNHLGFSPKQFR 246
Cdd:COG4977  283 AACGFGSASHFRRAFRRRFGVSPSAYR 309
PRK10371 PRK10371
transcriptional regulator MelR;
128-246 7.05e-12

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 66.77  E-value: 7.05e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 128 KETVIRYKEKYIPQVainhpifiqgLSYIHSKVSDTLSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKL 207
Cdd:PRK10371 182 KNSVSRHAQFYVSQM----------LGFIAENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRAL 251

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 488363483 208 LLSTDDSINAISERSGFSSHTNFTNQFKNHLGFSPKQFR 246
Cdd:PRK10371 252 LSDTDKSILDIALTAGFRSSSRFYSTFGKYVGMSPQQYR 290
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 140-246 5.68e-09

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 58.53  E-value: 5.68e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 140 PQVAINHPIFIQGLSYIHSKVSDTLSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAiKLLLSTDDSINAIS 219
Cdd:COG2169   77 PGSPPRADLVARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRA-RQLLQTGLSVTDAA 155

                         90       100
                 ....*....|....*....|....*..
gi 488363483 220 ERSGFSSHTNFTNQFKNHLGFSPKQFR 246
Cdd:COG2169  156 YAAGFGSLSRFYEAFKKLLGMTPSAYR 182
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
155-246 1.26e-05

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 47.66  E-value: 1.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 155 YIHSKVSDTLSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLLSTDDSINAISERSGFSSHTNFTNQF 234
Cdd:PRK10572 191 YISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVF 270

                         90
                 ....*....|..
gi 488363483 235 KNHLGFSPKQFR 246
Cdd:PRK10572 271 KKCTGASPSEFR 282
PRK11511 PRK11511
MDR efflux pump AcrAB transcriptional activator MarA;
153-246 4.88e-05

MDR efflux pump AcrAB transcriptional activator MarA;


Pssm-ID: 236920 [Multi-domain]  Cd Length: 127  Bit Score: 43.55  E-value: 4.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488363483 153 LSYIHSKVSDTLSLREVANYCNISESYCSNLFVRYLNMNFKDYFTSLKVIYAIKLLLSTDDSINAISERSGFSSHTNFTN 232
Cdd:PRK11511  15 LDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTR 94

                         90
                 ....*....|....
gi 488363483 233 QFKNHLGFSPKQFR 246
Cdd:PRK11511  95 TFKNYFDVPPHKYR 108
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
195-247 3.26e-04

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 43.13  E-value: 3.26e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 488363483 195 YFTSLKVIYAIKLLLSTDDSINAISERSGFSSHTNFTNQFKNHLGFSPKQFRS 247
Cdd:PRK13503 219 YLNRLRLLKARHLLRHSDASVTDIAYRCGFGDSNHFSTLFRREFSWSPRDIRQ 271
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 212-248 1.25e-03

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 41.56  E-value: 1.25e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 488363483 212 DDSINAISERSGFSSHTNFTNQFKNHLGFSPKQFRSM 248
Cdd:PRK09685 264 DEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRRK 300
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 205-246 3.07e-03

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 35.98  E-value: 3.07e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 488363483  205 IKLLLSTDDSINAISERSGFSShTNFTNQFKNHLGFSPKQFR 246
Cdd:pfam00165   1 LRENLSTNLTIADIADELGFSR-SYFSRLFKKYTGVTPSQYR 41
ftrA PRK09393
transcriptional activator FtrA; Provisional
 200-246 3.53e-03

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 39.95  E-value: 3.53e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 488363483 200 KVIYAIKLLLSTDDSINAISERSGFSSHTNFTNQFKNHLGFSPKQFR 246
Cdd:PRK09393 271 RLARARDLLESSALSIDQIAERAGFGSEESLRHHFRRRAATSPAAYR 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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