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Conserved domains on  [gi|488193081|ref|WP_002264289|]
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ABC transporter permease [Streptococcus mutans]

Protein Classification

ABC transporter permease( domain architecture ID 10790725)

ABC transporter permease is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

Gene Ontology:  GO:0043190|GO:0140359|GO:0042626|GO:0016020|GO:0006826
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
CeuB COG4606
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
 6-319 1.12e-146

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 443656  Cd Length: 318  Bit Score: 415.29  E-value: 1.12e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   6 TVPVLGAAAVFLSLVSIFIGVKSLSLFELGSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAG 85
Cdd:COG4606    3 KLRLLILLLLVLSILSLFIGVSDVSLSDLLSLDPEALQILLISRLPRTLAILLAGASLSVAGLIMQQLTRNRFVEPTTAG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  86 TMDWAKLGVVVTIILFSKSSLLLQLIISSVFVIFGSLFFIYLLKVIKFKDDVFIPLVGLMLGKVVSAISTFLGVQFQILQ 165
Cdd:COG4606   83 TMESAKLGILVALLLFPGASLLGKMLVAFVFALAGTLLFLAILRRIPFKDALLVPLVGLMLGGVISAITTFFAYRFDLLQ 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 166 SVNSWLEGHFSIMTSHRYEILFLVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMTAIIVTVVGSL 245
Cdd:COG4606  163 SLSSWLQGDFSGVLRGRYELLWLSAPLAVLAYLYADRFTIAGMGEDFATNLGLNYRRVVNLGLVIVALITAVVVVTVGSI 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488193081 246 PFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFLYFLMKGRRR 319
Cdd:COG4606  243 PFLGLIVPNIVSLYMGDNLRRTLPWVALLGAGFVLACDILGRLIIYPYEIPIGTVVGVVGSAIFLYLLLRRRRR 316
 
Name Accession Description Interval E-value
CeuB COG4606
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
 6-319 1.12e-146

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443656  Cd Length: 318  Bit Score: 415.29  E-value: 1.12e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   6 TVPVLGAAAVFLSLVSIFIGVKSLSLFELGSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAG 85
Cdd:COG4606    3 KLRLLILLLLVLSILSLFIGVSDVSLSDLLSLDPEALQILLISRLPRTLAILLAGASLSVAGLIMQQLTRNRFVEPTTAG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  86 TMDWAKLGVVVTIILFSKSSLLLQLIISSVFVIFGSLFFIYLLKVIKFKDDVFIPLVGLMLGKVVSAISTFLGVQFQILQ 165
Cdd:COG4606   83 TMESAKLGILVALLLFPGASLLGKMLVAFVFALAGTLLFLAILRRIPFKDALLVPLVGLMLGGVISAITTFFAYRFDLLQ 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 166 SVNSWLEGHFSIMTSHRYEILFLVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMTAIIVTVVGSL 245
Cdd:COG4606  163 SLSSWLQGDFSGVLRGRYELLWLSAPLAVLAYLYADRFTIAGMGEDFATNLGLNYRRVVNLGLVIVALITAVVVVTVGSI 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488193081 246 PFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFLYFLMKGRRR 319
Cdd:COG4606  243 PFLGLIVPNIVSLYMGDNLRRTLPWVALLGAGFVLACDILGRLIIYPYEIPIGTVVGVVGSAIFLYLLLRRRRR 316
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 15-315 2.52e-56

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 184.65  E-value: 2.52e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   15 VFLSLVSIFIGVKSLSLFE-----LGSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAGTMDW 89
Cdd:pfam01032   3 LLLILLSLFIGAVKISPSDvfsalLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   90 AKLGVVVTIILFSKSSLLLQLIISSVFVIFGSLFFIYLLKVIKFKDDVFIPLVGLMLGKVVSAISTFLGVQF--QILQSV 167
Cdd:pfam01032  83 AALGAVLAILLGGSLSLFALPLAAFIGALLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSLLLLLLnpEALQSI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  168 NSWLEGHFSIMT-SHRYEILFLVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMTAIIVTVVGSLP 246
Cdd:pfam01032 163 LFWLMGSLSGANwSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIG 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488193081  247 FLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFLYFLMK 315
Cdd:pfam01032 243 FVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 53-313 2.43e-30

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 115.35  E-value: 2.43e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  53 TVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAGTMDWAKLGVVVTIILFSKSSLLLQLIIssVFVIFGSLFFIYLLKVIK 132
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAF--AFAGALAIALLVLLLASR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 133 FKDDVF-IPLVGLMLGKVVSAISTFLGVQF-QILQSVNSWLEGHFSIMT-SHRYEILFLVLPCMVLIYLYAHQFTIAGLG 209
Cdd:cd06550   79 GGLSPSkLILIGIVLSAFFSAGVILISLLSdDSLQDLNIWLFGSILGVTwEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 210 EDFSKNLGLNYQFIINLGLVLVSVMTAIIVTVVGSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLv 289
Cdd:cd06550  159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRT- 237

                        250       260
                 ....*....|....*....|....
gi 488193081 290 IFPYEVSIGLTMGIIGSIFFLYFL 313
Cdd:cd06550  238 LLPSELPVGPVTALLGAPYFLYLL 261
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
9-319 2.12e-27

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 112.24  E-value: 2.12e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   9 VLGAAAVFLSLVSIFIGVkslSLFELGSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAGTMD 88
Cdd:PRK10577 360 ALGLLLLLALVVALSFGR---DAHGWNWLSGQLLDALLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISS 436

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  89 WAKLGVVVTIILFSKSSLLLQLIISSVFViFGSLFFIYLL-KVIKFKDDVFIpLVGLMLGKVVSAISTFLGVQ-----FQ 162
Cdd:PRK10577 437 GAGLGVVLALFLVPGAGFGWLLAAALLGA-LAALALILLLaRRGGFAPERLL-LTGIALSALFTALIQLLLASgdpraAQ 514

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 163 ILqsvnSWLEGHfsimTSHR-YEILFLVLPCMVLI----YLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMTAI 237
Cdd:PRK10577 515 LL----TWLSGS----TYGVtWAQALPLLIVAVLLlalaLLLRRWLDLLPLGDDTARALGLPVTRARLALLLLAALLTAA 586

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 238 IVTVVGSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFLYFLMKGR 317
Cdd:PRK10577 587 ATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSR 666


                 ..
gi 488193081 318 RR 319
Cdd:PRK10577 667 RR 668
 
Name Accession Description Interval E-value
CeuB COG4606
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
 6-319 1.12e-146

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443656  Cd Length: 318  Bit Score: 415.29  E-value: 1.12e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   6 TVPVLGAAAVFLSLVSIFIGVKSLSLFELGSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAG 85
Cdd:COG4606    3 KLRLLILLLLVLSILSLFIGVSDVSLSDLLSLDPEALQILLISRLPRTLAILLAGASLSVAGLIMQQLTRNRFVEPTTAG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  86 TMDWAKLGVVVTIILFSKSSLLLQLIISSVFVIFGSLFFIYLLKVIKFKDDVFIPLVGLMLGKVVSAISTFLGVQFQILQ 165
Cdd:COG4606   83 TMESAKLGILVALLLFPGASLLGKMLVAFVFALAGTLLFLAILRRIPFKDALLVPLVGLMLGGVISAITTFFAYRFDLLQ 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 166 SVNSWLEGHFSIMTSHRYEILFLVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMTAIIVTVVGSL 245
Cdd:COG4606  163 SLSSWLQGDFSGVLRGRYELLWLSAPLAVLAYLYADRFTIAGMGEDFATNLGLNYRRVVNLGLVIVALITAVVVVTVGSI 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488193081 246 PFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFLYFLMKGRRR 319
Cdd:COG4606  243 PFLGLIVPNIVSLYMGDNLRRTLPWVALLGAGFVLACDILGRLIIYPYEIPIGTVVGVVGSAIFLYLLLRRRRR 316
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 15-315 2.52e-56

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 184.65  E-value: 2.52e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   15 VFLSLVSIFIGVKSLSLFE-----LGSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAGTMDW 89
Cdd:pfam01032   3 LLLILLSLFIGAVKISPSDvfsalLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   90 AKLGVVVTIILFSKSSLLLQLIISSVFVIFGSLFFIYLLKVIKFKDDVFIPLVGLMLGKVVSAISTFLGVQF--QILQSV 167
Cdd:pfam01032  83 AALGAVLAILLGGSLSLFALPLAAFIGALLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSLLLLLLnpEALQSI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  168 NSWLEGHFSIMT-SHRYEILFLVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMTAIIVTVVGSLP 246
Cdd:pfam01032 163 LFWLMGSLSGANwSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIG 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488193081  247 FLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFLYFLMK 315
Cdd:pfam01032 243 FVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 21-317 3.98e-43

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 150.22  E-value: 3.98e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  21 SIFIGVKSLSLFEL------GSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAGTMDWAKLGV 94
Cdd:COG0609    1 SLSLGAVPISLSDVlrallgPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  95 VVTIILFSKSSLLLQLIISSVFViFGSLFFIYLL-KVIKFKDDVFIPLVGLMLGKVVSAISTFLGVQF--QILQSVNSWL 171
Cdd:COG0609   81 VLAIVLGGGLSALGLPLAAFLGA-LLAALLVYLLaRRGGGLSPLRLVLAGVAVSALFSALTSLLLLLAdpEQLRSIVFWL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 172 EGHFSIMT-SHRYEILFLVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMTAIIVTVVGSLPFLGL 250
Cdd:COG0609  160 MGSLAGASwDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGL 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488193081 251 IVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFLYFLMKGR 317
Cdd:COG0609  240 VVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 53-313 2.43e-30

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 115.35  E-value: 2.43e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  53 TVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAGTMDWAKLGVVVTIILFSKSSLLLQLIIssVFVIFGSLFFIYLLKVIK 132
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAF--AFAGALAIALLVLLLASR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 133 FKDDVF-IPLVGLMLGKVVSAISTFLGVQF-QILQSVNSWLEGHFSIMT-SHRYEILFLVLPCMVLIYLYAHQFTIAGLG 209
Cdd:cd06550   79 GGLSPSkLILIGIVLSAFFSAGVILISLLSdDSLQDLNIWLFGSILGVTwEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 210 EDFSKNLGLNYQFIINLGLVLVSVMTAIIVTVVGSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLv 289
Cdd:cd06550  159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRT- 237

                        250       260
                 ....*....|....*....|....
gi 488193081 290 IFPYEVSIGLTMGIIGSIFFLYFL 313
Cdd:cd06550  238 LLPSELPVGPVTALLGAPYFLYLL 261
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
9-319 2.12e-27

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 112.24  E-value: 2.12e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   9 VLGAAAVFLSLVSIFIGVkslSLFELGSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAGTMD 88
Cdd:PRK10577 360 ALGLLLLLALVVALSFGR---DAHGWNWLSGQLLDALLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISS 436

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  89 WAKLGVVVTIILFSKSSLLLQLIISSVFViFGSLFFIYLL-KVIKFKDDVFIpLVGLMLGKVVSAISTFLGVQ-----FQ 162
Cdd:PRK10577 437 GAGLGVVLALFLVPGAGFGWLLAAALLGA-LAALALILLLaRRGGFAPERLL-LTGIALSALFTALIQLLLASgdpraAQ 514

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 163 ILqsvnSWLEGHfsimTSHR-YEILFLVLPCMVLI----YLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMTAI 237
Cdd:PRK10577 515 LL----TWLSGS----TYGVtWAQALPLLIVAVLLlalaLLLRRWLDLLPLGDDTARALGLPVTRARLALLLLAALLTAA 586

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 238 IVTVVGSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFLYFLMKGR 317
Cdd:PRK10577 587 ATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSR 666


                 ..
gi 488193081 318 RR 319
Cdd:PRK10577 667 RR 668
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-320 3.33e-24

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 102.99  E-value: 3.33e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   1 MKKVLTVPVLGAAAVFLSLVSIFIGVKSLSLFELGSL------DDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLT 74
Cdd:PRK10577   8 RRARLPALLLALLLLLALALTLTQLSAALPLSQWLQAlwgpdaDDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQQVL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  75 QNKFVSPTTAGTMDWAKLGVVVTIILFsksslLLQLIISSVFVIF-GSLF---FIYLLKVIKFKDDVFIPLVGLMLGKVV 150
Cdd:PRK10577  88 RNPLASPTTLGVAAGAQLALVLATLFA-----PALLALASQLAAFaGGLLaaaLVFALAGGKRLSPLRLVLAGMVVSLYL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 151 SAISTFLGV-QFQILQSVNSWLEGhfSIMTSHRYEILFL---VLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINL 226
Cdd:PRK10577 163 GALTTLLLLfNEQYLQGLFLWGAG--SLAQNDWSGVQRLlprLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 227 GLVLVSVMTAIIVTVVGSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPY--EVSIGLTMGII 304
Cdd:PRK10577 241 ALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLAGVGgeLLPTGAVTALI 320

                        330
                 ....*....|....*.
gi 488193081 305 GSIFFLYFLMKGRRRS 320
Cdd:PRK10577 321 GAPLLLWLLPRLRSAQ 336
btuC PRK09535
cobalamin ABC transporter permease BtuC;
5-319 1.79e-21

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 93.28  E-value: 1.79e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   5 LTVPVLGAAAVFLSLVSIFIGVKSLSLFELGsLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTA 84
Cdd:PRK09535  52 VAVTTHGVPVLSVGLSLPAPDLEYASPFSFA-VPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSII 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  85 GTMDWAKLGVVVTIILFSKSSLLLQLiisSVFVifGSLFFIYLLKVIKFKDDVfIPLVGLMLGKVvsAISTFLG--VQFQ 162
Cdd:PRK09535 131 GVSSGAAVGAVAAIVLPLAVPFGLQA---AAFA--GALVAAFGVYAIATENGR-TPVATLLLAGV--AVQTFLGavISYL 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 163 ILQSVNS------WLEGHFSIMTSHRYEI-LFLVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMT 235
Cdd:PRK09535 203 LLHSGESlrravyWLMGHLHGSTWSDVEVaLPVVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVT 282

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 236 AIIVTVVGSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVifPYEVSIGLTMGIIGSIFFLYFLmk 315
Cdd:PRK09535 283 AAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLPTSALAGASFLVATDTVARSG--PAEVPVGIVTAALGAPFFLYLL-- 358


                 ....
gi 488193081 316 gRRR 319
Cdd:PRK09535 359 -RTR 361
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 9-320 2.01e-19

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 86.93  E-value: 2.01e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   9 VLGAAAVFLSLVSIFIGVKSLSLFELGSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAGTMD 88
Cdd:PRK03784  18 LLGLSVLLLLALLLSLCAGEQWISPGDWLSPRGELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSN 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  89 WAKLGVVVTIILFSKsslLLQLIISSVFVIFGSLFFIYLLKVIKFKDDVF---IPLVGLMLGKVVSAISTFLgVQF---Q 162
Cdd:PRK03784  98 GAGVALVAAVLLGQG---LLPPWALSLCAIAGALLITLILLRFARRHRLStsrLLLAGVALGIICSALMTWA-VYFstsL 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 163 ILQSVNSWLEGHFSIMTSHRYEILFLVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMTAIIVTVV 242
Cdd:PRK03784 174 DLRQLMYWMMGGFGGVDWRQSWLMLALLPVLIWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALA 253

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488193081 243 GSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFLYFLMKGRRRS 320
Cdd:PRK03784 254 GAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSHRAR 331
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
7-319 1.32e-18

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 84.75  E-value: 1.32e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   7 VPVLGAAAVF-LSLVSIF----IGVKSLSLFELGSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSP 81
Cdd:PRK11228   4 LPVAALIGLFwLSLFCYSaipiSAADALNALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  82 TTAGTMDWAKLGVVVTIILfsKSSLLLQLIISSVFVIFGSLFFIYLLKVIKFKDDVFIPLVGLMLGKVVSAISTFLGVQF 161
Cdd:PRK11228  84 SLLGINSGAALAMALTSAL--SPTPFAGYSLAFIAACGGGLSWLLVMTAGGGWRHTHDRNRLILAGIALSALCMALTRIT 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 162 QIL-----QSVNSWLEGHFSIMTSHRYEILF-LVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMT 235
Cdd:PRK11228 162 LLLaedhaYGIFYWLAGGVSHARWQEVWQLLpFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLV 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 236 AIIVTVVGSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFLYFlmk 315
Cdd:PRK11228 242 GACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWL--- 318


                 ....
gi 488193081 316 GRRR 319
Cdd:PRK11228 319 ARRR 322
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
2-317 1.64e-18

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 84.33  E-value: 1.64e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   2 KKVLTVPVLGAAAVFLSLVSIFIGVKSLSLFELGS---LDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKF 78
Cdd:PRK09777   1 MKIALVIFITLALAGCALLSLRMGVIPLPWRALLTdwqAGDEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  79 VSPTTAGTMDWAKLGVVVTIILFSKssllLQLIISSVFVIFGSLFFIYLLKVI-KFKDDVFIPLVGLMLGKVVSAISTFL 157
Cdd:PRK09777  81 ASPDILGVNHAASLASVGALLLFPS----LPVMWLPLLAFIGGMAGLILLKMLaGTHQPMKLALTGVALSALWASLTDYL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 158 GVQFQilQSVNS---WLEGHfsiMTSHRYEILFLVLPCMVLI----YLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVL 230
Cdd:PRK09777 157 MLSRP--QDINNallWLTGS---LWGRDWSFVKVALPWLILLlplsLSFCRDLDLLALGDARATTLGVSVPHTQFWALLL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 231 VSVMTAIIVTVVGSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIFPYEVSIGLTMGIIGSIFFL 310
Cdd:PRK09777 232 AVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFF 311


                 ....*..
gi 488193081 311 YFLMKGR 317
Cdd:PRK09777 312 WLLVRMR 318
CeuC COG4605
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
 9-319 5.45e-18

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443655  Cd Length: 317  Bit Score: 82.85  E-value: 5.45e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   9 VLGAAAVFLSLVSIFIGVKslslfelGSLDdsqlnILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNKFVSPTTAGtMD 88
Cdd:COG4605   11 LLALLALLAAALFLFYGLP-------GNWD-----YILPRRGTKLAAMLLVAIAIAVSTVLFQTITNNRILTPSIMG-FD 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  89 WAKLGVVVTIILFSKSSLLLQL------IISSVFVIFGSLFFIYLLKVIKFKDDVFIPLVGLMLGKVVSAISTFLGV--- 159
Cdd:COG4605   78 SLYVLIQTLLVFFLGSAGLAALnpllnfLLEVALMVGFSLLLYRWLFRGGRRNLHLLLLVGVVLGTLFRSLSSFLQRlid 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 160 --QFQILQSVnswLEGHFSIMTSHRYEI-LFLVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSVMTA 236
Cdd:COG4605  158 pnEFDVLQDR---LFASFNNVNTDLLLIaAVIVLLALLLLWRLRRRLDVLALGRDQAINLGVDYRRVVRRLLILVAVLVA 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 237 IIVTVVGSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLicdIFGRLV---IFPYEVSIGLTMGIIGSIFFLYFL 313
Cdd:COG4605  235 VSTALVGPITFLGLLVANLAYQLFGTYRHRYLLPAAALIGVIAL---VGGQFVvehVFNFSTTLSVIIEFVGGIYFLYLL 311


                 ....*.
gi 488193081 314 MKGRRR 319
Cdd:COG4605  312 LRKRRL 317
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
3-319 1.80e-15

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 75.90  E-value: 1.80e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081   3 KVLTVPVLGAAAVFLSLVSIFIGVKSLSLFE-----LGSLDDSQLNILLSSRIPRTVSILIAGSSLAVCGLIMQQLTQNK 77
Cdd:PRK10441   9 RAIAVPGLLLLLIIATALSLLIGAKSLPASVvlealSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNP 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081  78 FVSPTTAGTMDWAKLGVVVTIILFSKSSLLLQLIISSVFVIFGSL--FFIYLLKVIKFkDDVFIPLVGLMLGKVVSAIST 155
Cdd:PRK10441  89 LADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLivAFTGSQGGGQL-SPVRLTLAGVALAAVLEGLTS 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 156 FLGV-QFQILQSVNSWLEGHFSIMTSHRYE-ILFLVLPCMVLIYLYAHQFTIAGLGEDFSKNLGLNYQFIINLGLVLVSV 233
Cdd:PRK10441 168 GIALlNPDVYDQLRFWQAGSLDIRNLHTLKvVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIGLLAITV 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488193081 234 MTAIIVTVVGSLPFLGLIVPNSISAIKGDNMKNNLILTSFLGAVIVLICDIFGRLVIfPYEVSIGLTMGIIGSIfFLYFL 313
Cdd:PRK10441 248 LCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLV-PGELRVSVVSAFIGAP-VLIFL 325


                 ....*.
gi 488193081 314 MKGRRR 319
Cdd:PRK10441 326 VRRKTR 331
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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