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Conserved domains on  [gi|488164603|ref|WP_002235811|]
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MULTISPECIES: DUF4400 domain-containing protein [Neisseria]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4400 super family cl14023
Domain of unknown function (DUF4400); This family of proteins is functionally uncharacterized. ...
 109-218 5.82e-14

Domain of unknown function (DUF4400); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 209 and 249 amino acids in length. There is a single completely conserved residue P that may be functionally important.


The actual alignment was detected with superfamily member pfam14348:

Pssm-ID: 449324  Cd Length: 204  Bit Score: 68.18  E-value: 5.82e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488164603  109 DFGYKFKNYLVPRMKYLQQFDTTLKVISLRLGNLALIVGISVIFAIPVLIDGLVMRAIRQENASRESAGIYHRAKYWRTG 188
Cdd:pfam14348  84 DFNNNLSWVYRYLEAYLLAAWYVTYVFLVRLAVLLLWLPLFLLLALVALVDGLVRRDLRRFGAGRESPFVYHHAKHLLIP 163

                          90       100       110
                  ....*....|....*....|....*....|....
gi 488164603  189 IIWLGCMIYMCVPISIPPYLLYLPLVA----AIW 218
Cdd:pfam14348 164 LFVLPWVLYLALPFSVHPNLILLPAALllglAIS 197
 
Name Accession Description Interval E-value
DUF4400 pfam14348
Domain of unknown function (DUF4400); This family of proteins is functionally uncharacterized. ...
 109-218 5.82e-14

Domain of unknown function (DUF4400); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 209 and 249 amino acids in length. There is a single completely conserved residue P that may be functionally important.


Pssm-ID: 433890  Cd Length: 204  Bit Score: 68.18  E-value: 5.82e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488164603  109 DFGYKFKNYLVPRMKYLQQFDTTLKVISLRLGNLALIVGISVIFAIPVLIDGLVMRAIRQENASRESAGIYHRAKYWRTG 188
Cdd:pfam14348  84 DFNNNLSWVYRYLEAYLLAAWYVTYVFLVRLAVLLLWLPLFLLLALVALVDGLVRRDLRRFGAGRESPFVYHHAKHLLIP 163

                          90       100       110
                  ....*....|....*....|....*....|....
gi 488164603  189 IIWLGCMIYMCVPISIPPYLLYLPLVA----AIW 218
Cdd:pfam14348 164 LFVLPWVLYLALPFSVHPNLILLPAALllglAIS 197
conj_TIGR03747 TIGR03747
integrating conjugative element membrane protein, PFL_4697 family; Members of this protein ...
 99-231 1.93e-13

integrating conjugative element membrane protein, PFL_4697 family; Members of this protein family are found occasionally on plasmids such as the Pseudomonas putida TOL plasmid pWWO_p085. Usually, however, they are found on the bacterial main chromosome in regions flanked by markers of conjugative transfer and/or transposition. [Mobile and extrachromosomal element functions, Plasmid functions]


Pssm-ID: 163459  Cd Length: 233  Bit Score: 66.92  E-value: 1.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488164603   99 NESLKAKSEADFGYKFKNYLVPRMKYLQQFDTTLKVISLRLGNLALIVGISVIFAIPVLIDGLVMRAIRQENASRESAGI 178
Cdd:TIGR03747 100 TVAAAGGRGRSLRYWAAWLYVYARDYLLAAVYVTLVFLVRLVILVLAIPLFLLAAFVGLVDGLVRRDLRRFGAGRESSFV 179

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 488164603  179 YHRAKYWRTGIIWLGCMIYMCVPISIPPYLLYLPLVAAI-WMIFMQAKYLKKYL 231
Cdd:TIGR03747 180 YHHAKRFVKPLMILPWVLYLSLPISIYPNLILLPAALLLgLAVSITASTFKKYL 233
 
Name Accession Description Interval E-value
DUF4400 pfam14348
Domain of unknown function (DUF4400); This family of proteins is functionally uncharacterized. ...
 109-218 5.82e-14

Domain of unknown function (DUF4400); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 209 and 249 amino acids in length. There is a single completely conserved residue P that may be functionally important.


Pssm-ID: 433890  Cd Length: 204  Bit Score: 68.18  E-value: 5.82e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488164603  109 DFGYKFKNYLVPRMKYLQQFDTTLKVISLRLGNLALIVGISVIFAIPVLIDGLVMRAIRQENASRESAGIYHRAKYWRTG 188
Cdd:pfam14348  84 DFNNNLSWVYRYLEAYLLAAWYVTYVFLVRLAVLLLWLPLFLLLALVALVDGLVRRDLRRFGAGRESPFVYHHAKHLLIP 163

                          90       100       110
                  ....*....|....*....|....*....|....
gi 488164603  189 IIWLGCMIYMCVPISIPPYLLYLPLVA----AIW 218
Cdd:pfam14348 164 LFVLPWVLYLALPFSVHPNLILLPAALllglAIS 197
conj_TIGR03747 TIGR03747
integrating conjugative element membrane protein, PFL_4697 family; Members of this protein ...
 99-231 1.93e-13

integrating conjugative element membrane protein, PFL_4697 family; Members of this protein family are found occasionally on plasmids such as the Pseudomonas putida TOL plasmid pWWO_p085. Usually, however, they are found on the bacterial main chromosome in regions flanked by markers of conjugative transfer and/or transposition. [Mobile and extrachromosomal element functions, Plasmid functions]


Pssm-ID: 163459  Cd Length: 233  Bit Score: 66.92  E-value: 1.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488164603   99 NESLKAKSEADFGYKFKNYLVPRMKYLQQFDTTLKVISLRLGNLALIVGISVIFAIPVLIDGLVMRAIRQENASRESAGI 178
Cdd:TIGR03747 100 TVAAAGGRGRSLRYWAAWLYVYARDYLLAAVYVTLVFLVRLVILVLAIPLFLLAAFVGLVDGLVRRDLRRFGAGRESSFV 179

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 488164603  179 YHRAKYWRTGIIWLGCMIYMCVPISIPPYLLYLPLVAAI-WMIFMQAKYLKKYL 231
Cdd:TIGR03747 180 YHHAKRFVKPLMILPWVLYLSLPISIYPNLILLPAALLLgLAVSITASTFKKYL 233
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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