|
Name |
Accession |
Description |
Interval |
E-value |
| mpl |
TIGR01081 |
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Alternate name: ... |
3-458 |
0e+00 |
|
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Alternate name: murein tripeptide ligase [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 130153 [Multi-domain] Cd Length: 448 Bit Score: 801.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 3 HIHIIGIGGTFMGGLAAIAKEAGFEVSGCDAKMYPPMSTQLEALGIDVYEGFDAAQLDEfKADVYVIGNVAKRGMDVVEA 82
Cdd:TIGR01081 1 HIHILGICGTFMGGLAMIAKQLGHEVTGSDANVYPPMSTQLEAQGIEIIEGFDAAQLEP-KPDLVVIGNAMKRGNPCVEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 83 ILNLGLPYISGPQWLSENVLHHHWVLGVAGTHGKTTTASMLAWVLEYAGLAPGFLIGGVPENFGVSARLPQtprqdpnsq 162
Cdd:TIGR01081 80 VLNLNLPYTSGPQWLHDFVLHDRWVLAVAGTHGKTTTASMLAWVLEQCGLKPGFLIGGVPGNFGVSARLGE--------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 163 SPFFVIEADEYDTAFFDKRSKFVHYRPRTAVLNNLEFDHADIFADLGAIQTQFHYLVRTVPSEGLIVCNGRQQSLQDTLD 242
Cdd:TIGR01081 151 SPFFVIEADEYDTAFFDKRSKFVHYRPRTLVLNNLEFDHADIFDDLKAIQRQFHHLVRTVPGEGLILCPGRDQSLKDTLA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 243 KGCWTPVEKFGTEHGWQAGEANADGS-FDVLLDGKTAGRVKWDLMGRHNRMNALAVIAAARHVGVDIQTACEALGAFKNV 321
Cdd:TIGR01081 231 KGCWSEQEFFGEQGEWQAEKITADGShFDVLLDGEKVGEVKWSLVGRHNMHNALMAIAAARHVGVAIEDACEALGSFVNA 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 322 KRRMEIKGTANGITVYDDFAHHPTAIETTIQGLRQRVGGARILAVLEPRSNTMKLGTMKSALPVSLKEADQVFCYAGG-V 400
Cdd:TIGR01081 311 KRRLELKGEANGITVYDDFAHHPTAIEATLQGLRQKVGGARILAVLEPRSNTMKLGVHKDDLAPSLGRADQVFLYQPGqI 390
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 488154010 401 DWDVAEALAPLGGRLNVGKDFDAFVAEIVKNAEVGDHILVMSNGGFGGIHGKLLEALR 458
Cdd:TIGR01081 391 PWDVAEVAAQCVQPANVSADFDAFVAMIVKNAQPGDHILVMSNGGFGGIHGKLLDALR 448
|
|
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
1-455 |
0e+00 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 572.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 1 MKHIHIIGIGGTFMGGLAAIAKEAGFEVSGCDAKMYPpMSTQLEALGIDVYEGFDAAQLDEfkADVYVIGNVAKRGMDVV 80
Cdd:COG0773 4 IMHIHFIGIGGIGMSGLAEILLALGYKVSGSDLAESP-MTERLEALGIPVFIGHDAENIDD--ADLVVVSSAIPRDNPEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 81 EAILNLGLPYISGPQWLSENvLHHHWVLGVAGTHGKTTTASMLAWVLEYAGLAPGFLIGGVPENFGVSARLpqtprqdpn 160
Cdd:COG0773 81 VAARERGIPVLSRAEMLAEL-MRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFGTNARL--------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 161 SQSPFFVIEADEYDTAFfdkrskfVHYRPRTAVLNNLEFDHADIFADLGAIQTQFHYLVRTVPSEGLIVCNGRQQSLQDT 240
Cdd:COG0773 151 GDGDYFVAEADESDGSF-------LHYSPDIAVVTNIEADHLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLREL 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 241 LDKgCWTPVEKFGTEHG--WQAGEANADG---SFDVLLDGKTAGRVKWDLMGRHNRMNALAVIAAARHVGVDIQTACEAL 315
Cdd:COG0773 224 LPR-CGRPVITYGFSEDadYRAENIRIDGggsTFDVLRRGEELGEVELNLPGRHNVLNALAAIAVALELGVDPEAIAEAL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 316 GAFKNVKRRMEIKGTANGITVYDDFAHHPTAIETTIQGLRQRVGGARILAVLEPRSNTMkLGTMKSALPVSLKEADQVFC 395
Cdd:COG0773 303 ASFKGVKRRFELKGEVGGVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYSR-TRDFLDEFAEALSLADEVIL 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 396 Y----AG-----GVD-WDVAEALAPLGGRLNVGKDFDAFVAEIVKNAEVGDHILVMSNGGFGGIHGKLLE 455
Cdd:COG0773 382 LdiyaARekpipGVSsEDLAEAIRKRGKDVVYVPDLDELVEALAEIARPGDVVLTMGAGDIGGLGEKLLE 451
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
3-454 |
3.39e-76 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 244.91 E-value: 3.39e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 3 HIHIIGIGGTFMGGLAAIAKEAGFEVSGCDAKMYPpMSTQLEALGIDVYEGFDAAQLDEfkADVYVIGNVAKRGMDVVEA 82
Cdd:TIGR01082 1 KIHFVGIGGIGMSGIAEILLNRGYQVSGSDIAENA-TTKRLEALGIPIYIGHSAENLDD--ADVVVVSAAIKDDNPEIVE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 83 ILNLGLPYISGPQWLSEnVLHHHWVLGVAGTHGKTTTASMLAWVLEYAGLAPGFLIGGVPENFGVSARLpqtprqdpnSQ 162
Cdd:TIGR01082 78 AKERGIPVIRRAEMLAE-LMRFRHSIAVAGTHGKTTTTAMIAVILKEAGLDPTVVVGGLVKEAGTNARL---------GS 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 163 SPFFVIEADEYDtaffdkrSKFVHYRPRTAVLNNLEFDHADIF-ADLGAIQTQFHYLVRTVPSEGLIVCNGRQQSLQDTL 241
Cdd:TIGR01082 148 GEYLVAEADESD-------ASFLHLQPNVAIVTNIEPDHLDTYgSSFERLKAAFEKFIHNLPFYGLAVICADDPVLRELV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 242 DKGCWTPVEKFGTEHGWQAGEAN-----ADGSFDVLLDGKTAGRVKWDLMGRHNRMNALAVIAAARHVGVDIQTACEALG 316
Cdd:TIGR01082 221 PKATEQVITYGGSGEDADYRAENiqqsgAEGKFSVRGKGKLYLEFTLNLPGRHNVLNALAAIAVALELGIDFEAILRALA 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 317 AFKNVKRRMEIKGTANGITVYDDFAHHPTAIETTIQGLRQRVGGARILAVLEPR--SNTMKLGT--MKsalpvSLKEADQ 392
Cdd:TIGR01082 301 NFQGVKRRFEILGEFGGVLLIDDYAHHPTEIKATLKAARQGYPDKRIVVVFQPHrySRTRDLFDdfAK-----VLSDADE 375
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488154010 393 VF---CYA------GGVDW-DVAEALAPLGGR-LNVGKDFDAFVAEIVKNAEVGDHILVMSNGGFGGIHGKLL 454
Cdd:TIGR01082 376 LIlldIYAageepiNGIDGkSLARKITQLGKIePYFVPDLAELVEFLAAVLQSGDLILTMGAGDIIKLARELL 448
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
3-393 |
2.53e-42 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 159.98 E-value: 2.53e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 3 HIHIIGIGGTFMGGLAAIAKEAGFEVSGCDAKMYPPMStQLEALGIDVYEGFDAAQLDEFKADVYVIGnVAKRGMDVVEA 82
Cdd:PRK14573 6 FYHFIGIGGIGMSALAHILLDRGYSVSGSDLSEGKTVE-KLKAKGARFFLGHQEEHVPEDAVVVYSSS-ISKDNVEYLSA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 83 IlNLGLPYISGPQWLSENVLHHHWVLgVAGTHGKTTTASMLAWVLEYAGLAPGFLIGGVPENF--GVSArlpqtprqdpn 160
Cdd:PRK14573 84 K-SRGNRLVHRAELLAELMQEQISIL-VSGSHGKTTVSSLITAIFQEAKKDPSYAIGGLNQEGlnGYSG----------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 161 sQSPFFVIEADEYDTAFfdkrskfVHYRPRTAVLNNLEFDHADIFA-DLGAIQTQFHYLVRTVPSEGLIVCNGRQQSLQD 239
Cdd:PRK14573 151 -SSEYFVAEADESDGSL-------KHYTPEFSVITNIDNEHLSNFEgDRELLLASIQDFARKVQQINKCFYNGDCPRLKG 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 240 TL-------DKGCWTPVEKFGTEhGWQAgeanadgSFDVLLDGKTAGRVKWDLMGRHNRMNALAVIAAARHVGVDIQTAC 312
Cdd:PRK14573 223 CLqghsygfSSSCDLHILSYYQE-GWRS-------YFSAKFLGVVYQDIELNLVGMHNVANAAAAMGIALTLGIDEGAIR 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 313 EALGAFKNVKRRMEIKGTANGITVYDDFAHHPTAIETTIQGLRQRVGGARILAVLEPRSNTMKLGTMKSaLPVSLKEADQ 392
Cdd:PRK14573 295 NALKGFSGVQRRLERKNSSETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQPHRFSRLRECLDS-FPSAFQDADE 373
|
.
gi 488154010 393 V 393
Cdd:PRK14573 374 V 374
|
|
| MurD |
COG0771 |
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ... |
1-339 |
3.33e-25 |
|
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440534 [Multi-domain] Cd Length: 445 Bit Score: 107.47 E-value: 3.33e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 1 MKHIHIIGIGGTfmgGLAAI--AKEAGFEVSGCDAKMYPPMS-TQLEALGIDVYEG-FDAAQLDEFkaDVYVI--GnVAK 74
Cdd:COG0771 4 GKKVLVLGLGKS---GLAAArlLAKLGAEVTVSDDRPAPELAaAELEAPGVEVVLGeHPEELLDGA--DLVVKspG-IPP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 75 RgMDVVEAILNLGLPYISGPQWLSEnVLHHHWVlGVAGTHGKTTTASMLAWVLEYAGLAPGflIGGvpeNFGVSA--RLP 152
Cdd:COG0771 78 D-HPLLKAARAAGIPVIGEIELAYR-LSPAPII-AITGTNGKTTTTTLIGHILKAAGLRVA--VGG---NIGTPLldLLL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 153 QTPRQDpnsqspFFVIEAdeydtaffdkrSKF-----VHYRPRTAVLNNLEFDHADIFADLGA-IQTQFHyLVRTVPSEG 226
Cdd:COG0771 150 EPEPPD------VYVLEL-----------SSFqlettPSLRPDVAVILNITPDHLDRHGSMEAyAAAKAR-IFANQTPDD 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 227 LIVCNGRQQSLQDTLDKGCwTPVEKFGTEHGwQAGEANADGsfDVLLDGKTAGRV----KWDLMGRHNRMNALAVIAAAR 302
Cdd:COG0771 212 YAVLNADDPLTRALAEEAK-ARVVPFSLKEP-LEGGAGLED--GKLVDRASGEELlpvdDLRLPGRHNLENALAALAAAR 287
|
330 340 350
....*....|....*....|....*....|....*..
gi 488154010 303 HVGVDIQTACEALGAFKNVKRRMEIKGTANGITVYDD 339
Cdd:COG0771 288 ALGVPPEAIREALRSFKGLPHRLEFVAEINGVRFIND 324
|
|
| MurE |
COG0769 |
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
106-366 |
3.86e-24 |
|
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440532 [Multi-domain] Cd Length: 459 Bit Score: 104.39 E-value: 3.86e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 106 WVLGVAGTHGKTTTASMLAWVLEYAGLAPGfLIGGVpeNFGVSARLPQTPRQDPNS---QSPFFVIEADEYDTAFFD--- 179
Cdd:COG0769 81 KLIGVTGTNGKTTTTYLLAQILRALGKKTG-LIGTV--GNGIGGELIPSSLTTPEAldlQRLLAEMVDAGVTHVVMEvss 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 180 -----KRSKFVHYRprTAVLNNLEFDHADifadlgaiqtqFH-----Y------LVRTVPSEGLIVCN-----GRQqsLQ 238
Cdd:COG0769 158 haldqGRVDGVRFD--VAVFTNLTRDHLD-----------YHgtmeaYfaakarLFDQLGPGGAAVINaddpyGRR--LA 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 239 DTLDKGCWTpvekFGTEHG--WQAG--EANADG-SFDVLLDGKTaGRVKWDLMGRHNRMNALAVIAAARHVGVDIQTACE 313
Cdd:COG0769 223 AAAPARVIT----YGLKADadLRATdiELSADGtRFTLVTPGGE-VEVRLPLIGRFNVYNALAAIAAALALGIDLEEILA 297
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 488154010 314 ALGAFKNVKRRMEIKGTANGITVYDDFAHHPTAIETTIQGLRQRVGGaRILAV 366
Cdd:COG0769 298 ALEKLKGVPGRMERVDGGQGPTVIVDYAHTPDALENVLEALRPHTKG-RLIVV 349
|
|
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
79-440 |
4.17e-21 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 95.17 E-value: 4.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 79 VVEAILNLGLPYIsgpqwLSENVLH------HHW-------VLGVAGTHGKTTTASMLAWVLE--YAGLAPgfliggvPE 143
Cdd:COG0770 66 LVSRPLPADLPLI-----VVDDTLKalqqlaAAHrarfnipVIAITGSNGKTTTKEMLAAVLStkGKVLAT-------PG 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 144 NF----GVS---ARLPQTPRqdpnsqspFFVIEA--------DEYdtaffdkrSKFVhyRPRTAVLNNLEFDHADIFADL 208
Cdd:COG0770 134 NFnneiGVPltlLRLPEDHE--------FAVLEMgmnhpgeiAYL--------ARIA--RPDIAVITNIGPAHLEGFGSL 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 209 GAI-QTQFHyLVRTVPSEGLIVCNG---RQQSLQDTLDKGCWTpvekFGTEHG--WQAG--EANADG-SFDVLLDGKTAg 279
Cdd:COG0770 196 EGIaRAKGE-IFEGLPPGGVAVLNAddpLLAALAERAKARVLT----FGLSEDadVRAEdiELDEDGtRFTLHTPGGEL- 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 280 RVKWDLMGRHNRMNALAVIAAARHVGVDIQTACEALGAFKNVKRRMEIKGTANGITVYDDfAHH--PTAIETTIQGLRQR 357
Cdd:COG0770 270 EVTLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLAAFQPVKGRLEVIEGAGGVTLIDD-SYNanPDSMKAALDVLAQL 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 358 VGGARILAVLeprsNTMK-LGTMKSAL------PVSLKEADQVFCYaGgvdwDVAEALAPLGGRLNVG--KDFDAFVAEI 428
Cdd:COG0770 349 PGGGRRIAVL----GDMLeLGEESEELhrevgeLAAELGIDRLFTV-G----ELARAIAEAAGGERAEhfEDKEELLAAL 419
|
410
....*....|..
gi 488154010 429 VKNAEVGDHILV 440
Cdd:COG0770 420 KALLRPGDVVLV 431
|
|
| murD |
TIGR01087 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation ... |
3-439 |
5.73e-20 |
|
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273436 [Multi-domain] Cd Length: 433 Bit Score: 91.63 E-value: 5.73e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 3 HIHIIGIGGTfMGGLAAIAKEAGFEVSGCDAK--MYPPMSTQLEALGIDVYEGFDAAQLDEFKADVYVIGNVAKRGMDVV 80
Cdd:TIGR01087 1 KILILGLGKT-GRAVARFLHKKGAEVTVTDLKpnEELEPSMGQLRLNEGSVLHTGLHLEDLNNADLVVKSPGIPPDHPLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 81 EAILNLGLPYISGPQ---WLSENVlhhhwVLGVAGTHGKTTTASMLAWVLEYAGLaPGFLIGgvpeNFGVSARlpQTPRQ 157
Cdd:TIGR01087 80 QAAAKRGIPVVGDIElflRLVPLP-----VVAITGTNGKTTTTSLLYHLLKAAGL-KAFLGG----NIGTPAL--EVLDQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 158 DPnsqSPFFVIEAdeydtaffdkrSKF-VHY----RPRTAVLNNLEFDHADIFADLGA-IQTQFHYLVRTvPSEGLIVCN 231
Cdd:TIGR01087 148 EG---AELYVLEL-----------SSFqLETteslRPEIALILNISEDHLDWHGSFEDyVAAKLKIFARQ-TEGDVAVLN 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 232 grqqslQDtlDKGCWTPVEKFGTEHGWQAGEANADGSFdVLLDGKTAGRVKWD---LMGRHNRMNALAVIAAARHVGVDI 308
Cdd:TIGR01087 213 ------AD--DPRFARLAQKSKAQVIWFSVEKDAERGL-CIRDGGLYLKPNDLegsLLGLHNAENILAAIALAKSLGLNL 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 309 QTACEALGAFKNVKRRMEIKGTANGITVYDDFAhhPTAIETTIQGLRQrVGGARILAVleprsntmkLGTMKSALPVSLK 388
Cdd:TIGR01087 284 EAILEALRSFKGLPHRLEYVGQKNGVHFYNDSK--ATNVHATLAALSA-FDNPVILIV---------GGDDKGADFSPLA 351
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 488154010 389 EADQ---VFCYAGGVDwdvAEALAPLGGRLNVG----KDFDAFVAEIVKNAEVGDHIL 439
Cdd:TIGR01087 352 PAAAgkvKAVLAIGED---AAKIAPLLKEAGLSvylvESLEEAVQAAREVASPGDVVL 406
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
110-301 |
8.83e-18 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 81.20 E-value: 8.83e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 110 VAGTHGKTTTASMLAWVLEYAGLA---PGFLIGGVPENFGVSARLPQTPRQDPNSQSPFFVIEADEYdtAFFDKRSKFVh 186
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGGVigtIGTYIGKSGNTTNNAIGLPLTLAEMVEAGAEYAVLEVSSH--GLGEGRLSGL- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 187 YRPRTAVLNNLEFDHADIFADLGAIQTQFHYLVRTVPSEGLIVCNG----RQQSLQDTLDKGCwtPVEKFGTE--HGWQA 260
Cdd:pfam08245 78 LKPDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINAddpyGAFLIAKLKKAGV--RVITYGIEgeADLRA 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 488154010 261 GEANAD---GSFDVL-LDGKTAGrVKWDLMGRHNRMNALAVIAAA 301
Cdd:pfam08245 156 ANIELSsdgTSFDLFtVPGGELE-IEIPLLGRHNVYNALAAIAAA 199
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
107-440 |
1.49e-15 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 79.36 E-value: 1.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 107 VLGVAGTHGKTTTASMLAWVLeyAGLAPGFLIGGVPENFGVSARLPQTP-RQDPNSQspFFVIEADEYDTAFFDKRSKFV 185
Cdd:PRK11929 605 VVAITGSNGKTTTKEMIAAIL--AAWQGEDRVLATEGNFNNEIGVPLTLlRLRAQHR--AAVFELGMNHPGEIAYLAAIA 680
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 186 hyRPRTAVLNNLEFDHADIFADLGAIQTQFHYLVRTVPSEGLIVCNG--RQQSLQDTLDKG-----------------CW 246
Cdd:PRK11929 681 --APTVALVTNAQREHQEFMHSVEAVARAKGEIIAALPEDGVAVVNGddPYTAIWAKLAGArrvlrfglqpgadvyaeKI 758
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 247 TPVEKFGTEHGWQageanadgsFDVLLDGKTAgRVKWDLMGRHNRMNALAVIAAARHVGVDIQTACEALGAFKNVKRRME 326
Cdd:PRK11929 759 AKDISVGEAGGTR---------CQVVTPAGSA-EVYLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQPVAGRMQ 828
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 327 IKGTANGITVYDD-FAHHPTAIETTIQGLRQRVGGARILAvleprsntmkLGTMKSALPVSLKEADQVFCYAG--GVD-- 401
Cdd:PRK11929 829 RRRLSCGTRIIDDtYNANPDSMRAAIDVLAELPNGPRALV----------LGDMLELGDNGPAMHREVGKYARqlGIDal 898
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 488154010 402 WDVAEALAPLG-----GRLNVGKDFDAFVAEIVKNAEVGDHILV 440
Cdd:PRK11929 899 ITLGEAARDAAaafgaGARGVCASVDEIIAALRGALPEGDSVLI 942
|
|
| murE |
PRK00139 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional |
285-366 |
2.08e-15 |
|
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Pssm-ID: 234660 [Multi-domain] Cd Length: 460 Bit Score: 77.86 E-value: 2.08e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 285 LMGRHNRMNALAVIAAARHVGVDIQTACEALGAFKNVKRRMEIKGTANGITVYDDFAHHPTAIETTIQGLRQRVGGaRIL 364
Cdd:PRK00139 274 LIGRFNVSNLLAALAALLALGVPLEDALAALAKLQGVPGRMERVDAGQGPLVIVDYAHTPDALEKVLEALRPHAKG-RLI 352
|
..
gi 488154010 365 AV 366
Cdd:PRK00139 353 CV 354
|
|
| murF |
TIGR01143 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the ... |
107-440 |
2.50e-14 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the strictly bacterial MurF gene of peptidoglycan biosynthesis. This enzyme is almost always UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, but in a few species, MurE adds lysine rather than diaminopimelate. This enzyme acts on the product from MurE activity, and so is also subfamily rather than equivalog. Staphylococcus aureus is an example of species in this MurF protein would differ. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273468 [Multi-domain] Cd Length: 417 Bit Score: 74.61 E-value: 2.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 107 VLGVAGTHGKTTTASMLAWVLE--YAGLAPgfliggvPENFGVSARLPQTPRQDPNSQSpFFVIE---------ADEYDT 175
Cdd:TIGR01143 76 VIGITGSSGKTTTKEMLAAILShkYKVFAT-------PGNFNNEIGLPLTLLRAPGDHD-YAVLEmgashpgeiAYLAEI 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 176 AffdkrskfvhyRPRTAVLNNLEFDHADIFADLGAIQTQFHYLVRTVPSEGLIVCNGRQQSLQDTLDKGCWTPVEKFGTE 255
Cdd:TIGR01143 148 A-----------KPDIAVITNIGPAHLEGFGSLEGIAEAKGEILQGLKENGIAVINADDPAFADLAKRLPNRNILSFGFE 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 256 HGWQAGEA---NADGS--FDVLLDGKTAgRVKWDLMGRHNRMNALAVIAAARHVGVDIQTACEALGAFKNVKRRMEIKgT 330
Cdd:TIGR01143 217 GGDFVAKDisySALGStsFTLVAPGGEF-EVSLPLLGRHNVMNALAAAALALELGIPLEEIAEGLAELKLVKGRFEVQ-T 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 331 ANGITVYDD-FAHHPTAIETTIQGLrQRVGGARILaVLeprsNTMK-LG----TMKSALPVSLKEADQVFCYAGGVDWDV 404
Cdd:TIGR01143 295 KNGLTLIDDtYNANPDSMRAALDAL-ARFPGKKIL-VL----GDMAeLGeyseELHAEVGRYANSLGIDLVFLVGEEAAV 368
|
330 340 350
....*....|....*....|....*....|....*.
gi 488154010 405 AEALAPLGGRlnVGKDFDAFVAEIVKNAEVGDHILV 440
Cdd:TIGR01143 369 IYDSFGKQGK--HFADKDELLAFLKTLVRKGDVVLV 402
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
3-105 |
2.98e-14 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 67.64 E-value: 2.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 3 HIHIIGIGGTFMGGLAAIAKEAGFEVSGCDAKmyppmsTQLEALGIDVYEGFDAAqldefkadvyvigNVAKRGMDVVEA 82
Cdd:pfam01225 1 EIHFVGIDGRGMSPGALFLALKGYRVDGSDFI------ESLIALGAAAVVGHDAA-------------NNISPDNPELEA 61
|
90 100
....*....|....*....|...
gi 488154010 83 ILNLGLPYISGPQWLSENVLHHH 105
Cdd:pfam01225 62 AKVPGIPVIDRREALAELAAAFY 84
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
107-355 |
6.55e-14 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 74.36 E-value: 6.55e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 107 VLGVAGTHGKTTTASMLAWVLEYAGLAPGFlIGGVpeNFGVSARLPQTPRQDPNS---QSPFFVIEADEYDTAFFDKRS- 182
Cdd:PRK11929 114 LVAVTGTNGKTSCAQLLAQLLTRLGKPCGS-IGTL--GARLDGRLIPGSLTTPDAiilHRILARMRAAGADAVAMEASSh 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 183 -----KFVHYRPRTAVLNNLEFDHADIFADLGAIQTQFHYLVRTVPSEGLIVCNGRQQSLQDTLDKGCwtpvekFGTEHG 257
Cdd:PRK11929 191 gleqgRLDGLRIAVAGFTNLTRDHLDYHGTMQDYEEAKAALFSKLPGLGAAVINADDPAAARLLAALP------RGLKVG 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 258 WQAGEANADGSFDVLLDGKTA---------GRVKWD--LMGRHNRMNALAVIAAARHVGVDIQTACEALGAFKNVKRRME 326
Cdd:PRK11929 265 YSPQNAGADVQARDLRATAHGqvftlatpdGSYQLVtrLLGRFNVSNLLLVAAALKKLGLPLAQIARALAAVSPVPGRME 344
|
250 260 270
....*....|....*....|....*....|..
gi 488154010 327 ---IKGTANGITVYDDFAHHPTAIETTIQGLR 355
Cdd:PRK11929 345 rvgPTAGAQGPLVVVDYAHTPDALAKALTALR 376
|
|
| Mur_ligase_C |
pfam02875 |
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase ... |
321-367 |
4.43e-11 |
|
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460731 [Multi-domain] Cd Length: 87 Bit Score: 58.89 E-value: 4.43e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 488154010 321 VKRRMEIKGTANGITVYDDFAHHPTAIETTIQGLRQRVGGaRILAVL 367
Cdd:pfam02875 1 VPGRLEVVGENNGVLVIDDYAHNPDAMEAALRALRNLFPG-RLILVF 46
|
|
| murE |
TIGR01085 |
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, ... |
107-366 |
7.17e-11 |
|
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase. An exception is Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is EC 6.3.2.7. The Mycobacteria, part of the closest neighboring branch outside of the low-GC Gram-positive bacteria, use diaminopimelate. A close homolog, scoring just below the trusted cutoff, is found (with introns) in Arabidopsis thaliana. Its role is unknown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273435 [Multi-domain] Cd Length: 464 Bit Score: 63.87 E-value: 7.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 107 VLGVAGTHGKTTTASMLAWVLEYAGLAPGFlIGGVPENFGVSARLPQTPRQD-PNS---QS----------PFFVIEADE 172
Cdd:TIGR01085 87 VIGVTGTNGKTTTTSLIAQLLRLLGKKTGL-IGTIGYRLGGNDLIKNPAALTtPEAltlQStlaemveagaQYAVMEVSS 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 173 YdtAFFDKRSKFVHYRprTAVLNNLEFDHADI---FADLGAIQTQfhyLVRTVPSEGLIVCN-----GRQqsLQDTLDKG 244
Cdd:TIGR01085 166 H--ALAQGRVRGVRFD--AAVFTNLSRDHLDFhgtMENYFAAKAS---LFTELGLKRFAVINlddeyGAQ--FVKRLPKD 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 245 CwtPVEKFGTEHGWQAG---EANADGSFD----VLLDGKTAGRVKWDLMGRHNRMNALAVIAAARHVG-VDIQTACEALG 316
Cdd:TIGR01085 237 I--TVSAITQPADGRAQdikITDSGYSFEgqqfTFETPAGEGHLHTPLIGRFNVYNLLAALATLLHLGgIDLEDIVAALE 314
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 488154010 317 AFKNVKRRMEIKGTANGITVYDDFAHHPTAIETTIQGLRQRVGGaRILAV 366
Cdd:TIGR01085 315 KFRGVPGRMELVDGGQKFLVIVDYAHTPDALEKALRTLRKHKDG-RLIVV 363
|
|
| murD |
PRK14106 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional |
2-339 |
1.14e-10 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
Pssm-ID: 184511 [Multi-domain] Cd Length: 450 Bit Score: 63.45 E-value: 1.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 2 KHIHIIGIGGTfmgGLAAIA--KEAGFEVSGCDAKMYPPMSTQLEAL---GIDVYEGFDAaqlDEFKADVYVIgnVAKRG 76
Cdd:PRK14106 6 KKVLVVGAGVS---GLALAKflKKLGAKVILTDEKEEDQLKEALEELgelGIELVLGEYP---EEFLEGVDLV--VVSPG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 77 M----DVVEAILNLGLPYISgpqwlsENVL----HHHWVLGVAGTHGKTTTASMLAWVLEYAGLAPgfLIGGvpeNFGVS 148
Cdd:PRK14106 78 VpldsPPVVQAHKKGIEVIG------EVELayrfSKAPIVAITGTNGKTTTTTLLGEIFKNAGRKT--LVAG---NIGYP 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 149 arlpqtprqdpnsqspfFVIEADEY--DTAFFDKRSKF-----VHYRPRTAVLNNLEFDHADifadlgaiqtqfhylvRT 221
Cdd:PRK14106 147 -----------------LIDAVEEYgeDDIIVAEVSSFqletiKEFKPKVGCILNITPDHLD----------------RH 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 222 VPSEGLIVCNGR---QQSLQD------------TLDKGCWTPVEKFGTEHGWQAGEANADGSFDVLLDGKTAGRVKWD-- 284
Cdd:PRK14106 194 KTMENYIKAKARifeNQRPSDytvlnyddprtrSLAKKAKARVIFFSRKSLLEEGVFVKNGKIVISLGGKEEEVIDIDei 273
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 488154010 285 -LMGRHNRMNALAVIAAARHVGVDIQTACEALGAFKNVKRRMEIKGTANGITVYDD 339
Cdd:PRK14106 274 fIPGEHNLENALAATAAAYLLGISPDVIANTLKTFKGVEHRIEFVAEINGVKFIND 329
|
|
| PRK14093 |
PRK14093 |
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; ... |
282-457 |
7.32e-07 |
|
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; Provisional
Pssm-ID: 184501 [Multi-domain] Cd Length: 479 Bit Score: 51.31 E-value: 7.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 282 KWDLMGRHNRMNALAVIAAARHVGVDIQTACEALGAFK-----NVKRRMEIK-GTAngiTVYDD-FAHHPTAIETTIQGL 354
Cdd:PRK14093 284 KLGMPGRHIAMNSLAVLAAAELAGADLALAALALSQVQpaagrGVRHTLEVGgGEA---TLIDEsYNANPASMAAALGVL 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 355 -RQRVGG-ARILAVLeprSNTMKLGTMKSALPVSLKEA------DQVFCyAGGVDWDVAEALaPLGGRLNVGKDFDAFVA 426
Cdd:PRK14093 361 gRAPVGPqGRRIAVL---GDMLELGPRGPELHRGLAEAiranaiDLVFC-CGPLMRNLWDAL-SSGKRGGYAEDAAALES 435
|
170 180 190
....*....|....*....|....*....|.
gi 488154010 427 EIVKNAEVGDhiLVMSNGGFGGIHGKLLEAL 457
Cdd:PRK14093 436 QVVAAIRAGD--VIMVKGSLGSRMKTIVTAL 464
|
|
| PRK14022 |
PRK14022 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase; |
108-366 |
9.11e-07 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase;
Pssm-ID: 237588 [Multi-domain] Cd Length: 481 Bit Score: 51.19 E-value: 9.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 108 LGVAGTHGKTTTASMLAWVLE-------YAGLApGFLIG--------GVPENFGVSARLPQTPRQDPNSqspfFVIEADE 172
Cdd:PRK14022 113 LAFTGTKGKTTAAYFAYHILKqlhkpamLSTMN-TTLDGetffksalTTPESLDLFKMMAEAVDNGMTH----LIMEVSS 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 173 YdtAFFDKRSKFVHYRprTAVLNNLEFDHADiFADLGAIQTQFHYLVRTVPSEGLIVCNGRQQSLQDTLDKGCWTPVEKF 252
Cdd:PRK14022 188 Q--AYLVGRVYGLTFD--VGVFLNITPDHIG-PIEHPTFEDYFYHKRLLMENSKAVVVNSDMDHFSELLEQVTPQEHDFY 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 253 GTEHGWQAGEANAdgsFDVLLDGKTAGRVKWDLMGRHNRMNALAVIAAARHVGV---DIQTACEAlgafKNVKRRMEIKG 329
Cdd:PRK14022 263 GIDSENQIMASNA---FSFEATGKLAGTYDIQLIGKFNQENAMAAGLACLRLGAsleDIQKGIAQ----TPVPGRMEVLT 335
|
250 260 270
....*....|....*....|....*....|....*..
gi 488154010 330 TANGITVYDDFAHHPTAIETTIQGLRQRVGGARILAV 366
Cdd:PRK14022 336 QSNGAKVFIDYAHNGDSLNKLIDVVEEHQKGKLILLL 372
|
|
| FolC |
COG0285 |
Folylpolyglutamate synthase/Dihydropteroate synthase [Coenzyme transport and metabolism]; ... |
74-440 |
7.41e-05 |
|
Folylpolyglutamate synthase/Dihydropteroate synthase [Coenzyme transport and metabolism]; Folylpolyglutamate synthase/Dihydropteroate synthase is part of the Pathway/BioSystem: Folate biosynthesis
Pssm-ID: 440054 [Multi-domain] Cd Length: 423 Bit Score: 44.71 E-value: 7.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 74 KRGMDVVEAILN-LGLPYISGPqwlsenVLHhhwvlgVAGTHGKTTTASMLAWVLEYAGLAPG-------------FLIG 139
Cdd:COG0285 20 KLGLERIRALLErLGNPQRKLP------VIH------VAGTNGKGSTAAMLESILRAAGYRVGlytsphlvrfnerIRIN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 140 GVPenfgVS-ARL--------PQTPRQDPNSQSPFfvieadEYDTA-----FFDKRskfVHY-----------------R 188
Cdd:COG0285 88 GEP----ISdEELvealeevePAVEEVDAGPPTFF------EVTTAaaflyFAEAP---VDVavlevglggrldatnviD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 189 PRTAVLNNLEFDHADIfadLGAiqtqfhylvrTVPS---E--GLI------VCNGRQQSLQDTL-----DKGCwtPVEKF 252
Cdd:COG0285 155 PLVSVITSIGLDHTDF---LGD----------TLEEiarEkaGIIkpgvpvVTGDQQPEALEVIeeraaELGA--PLYRA 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 253 GTEHGWqagEANADGSFDVLLDGKTAGRVKWDLMGRHNRMNALAVIAAARHV---GVDI-QTACEAlgAFKNVKR--RME 326
Cdd:COG0285 220 GRDFSV---EEREGAVFSYQGPGGEYEDLPLPLLGAHQAENAALALAALEALrelGLPIsEEAIRE--GLANARWpgRLE 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488154010 327 IKGTanGITVYDDFAHHPTAIETTIQGLRQRVGGARILAVleprsntmkLGTMK--------SALPvslKEADQVFC--- 395
Cdd:COG0285 295 VLSR--GPLVILDGAHNPAGARALAETLKELFPFRKLHLV---------FGMLAdkdiegmlAALA---PLADEVIVttp 360
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 488154010 396 -YAGGVDWD-VAEALAPLGGRLNVGKDFDAFVAEIVKNAEVGDHILV 440
Cdd:COG0285 361 pSPRALDAEeLAEAARELGLRVEVAPDVEEALEAALELADPDDLILV 407
|
|
| PRK14016 |
PRK14016 |
cyanophycin synthetase; Provisional |
107-136 |
3.58e-04 |
|
cyanophycin synthetase; Provisional
Pssm-ID: 237586 [Multi-domain] Cd Length: 727 Bit Score: 43.22 E-value: 3.58e-04
10 20 30
....*....|....*....|....*....|
gi 488154010 107 VLGVAGTHGKTTTASMLAWVLEYAGLAPGF 136
Cdd:PRK14016 482 IVAVTGTNGKTTTTRLIAHILKLSGKRVGM 511
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