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Conserved domains on  [gi|488141980|ref|WP_002213188|]
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MULTISPECIES: carbohydrate ABC transporter permease [Yersinia pseudotuberculosis complex]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 10003067)

carbohydrate ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of carbohydrate substrates including trehalose, lactose, arabinose, and maltodextrin

Gene Ontology:  GO:0042626|GO:0140359|GO:0008643|GO:0055085
PubMed:  25750732|24638992|30626703
TCDB:  3.A.1.1.-

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
23-286 5.07e-91

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 272.01  E-value: 5.07e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  23 FYTLGYAIYLSVHDIDLMSPPPfDFIGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISRDFFGRKLVR 102
Cdd:COG1175   36 LYPLLYTLYLSFTDWNLLGPPP-EFVGLDNYARLFTDPRFWNALGNTLLFTVVSVPLQLVLGLLLALLLNRKLRGRGFFR 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 103 ALLLLPMIVTPIVAGLIWRIFYDPNAGLFNWLAGLIGIPPIDWLGNPSTAMASLILADIWQWTPFIILLVSAGLDALPSE 182
Cdd:COG1175  115 TLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRE 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 183 PLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMIDAFKSFDLIYVMTRGGPALATETTNMYAYLTGFQDFRISAAVV 262
Cdd:COG1175  195 LYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGGGPGNSTTTLVLYIYQTAFQQFDFGYASA 274

                        250       260
                 ....*....|....*....|....
gi 488141980 263 IAIInTLLVIAVLSFASKKVMKDE 286
Cdd:COG1175  275 IAVV-LFLIILVLTLLQLRLLRRR 297
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
23-286 5.07e-91

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 272.01  E-value: 5.07e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  23 FYTLGYAIYLSVHDIDLMSPPPfDFIGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISRDFFGRKLVR 102
Cdd:COG1175   36 LYPLLYTLYLSFTDWNLLGPPP-EFVGLDNYARLFTDPRFWNALGNTLLFTVVSVPLQLVLGLLLALLLNRKLRGRGFFR 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 103 ALLLLPMIVTPIVAGLIWRIFYDPNAGLFNWLAGLIGIPPIDWLGNPSTAMASLILADIWQWTPFIILLVSAGLDALPSE 182
Cdd:COG1175  115 TLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRE 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 183 PLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMIDAFKSFDLIYVMTRGGPALATETTNMYAYLTGFQDFRISAAVV 262
Cdd:COG1175  195 LYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGGGPGNSTTTLVLYIYQTAFQQFDFGYASA 274

                        250       260
                 ....*....|....*....|....
gi 488141980 263 IAIInTLLVIAVLSFASKKVMKDE 286
Cdd:COG1175  275 IAVV-LFLIILVLTLLQLRLLRRR 297
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
27-272 2.93e-25

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 101.44  E-value: 2.93e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  27 GYAIYLSVHDIDlmsppPF----DFIGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISRDFFGRKLVR 102
Cdd:PRK10561  19 GEALWYSLQSVD-----PFgfssQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAALVDYVVRGSRFYQ 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 103 ALLLLPMIVTPIVAGLIWRIFYDPNAGLFNWLAGLIGippIDW--LGNPSTAMASLILADIWQWTPFIILLVSAGLDALP 180
Cdd:PRK10561  94 TLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFG---YDWnhAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIP 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 181 SEPLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMIDA-FKSFDLIYVMTRGGPALATETTNMYAYLTGFQDFRISA 259
Cdd:PRK10561 171 RSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAfFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLSS 250

                        250
                 ....*....|...
gi 488141980 260 AVVIAIINTLLVI 272
Cdd:PRK10561 251 SAAQSVVLMFLVI 263
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 66-272 2.21e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.00  E-value: 2.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  66 LWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGLIWrifydpnaglfnwlaGLIGIPPID 144
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARkRGKLDRLLRRIIDLLLSLPSLVLGLLL---------------VLLFGVLLG 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 145 WLGNPSTAMASLILADIWqWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMIDAFKS 224
Cdd:cd06261   66 WGILPGLGLPALILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGE 144

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 488141980 225 FDLIYVMTRGGPALAteTTNMYAYLTGFQDFRISAAVVIAIINTLLVI 272
Cdd:cd06261  145 FALVSFLGGGEAPGP--GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 46-284 1.57e-11

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 64.32  E-value: 1.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980   46 DFIGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGlIWRIFY 124
Cdd:TIGR03262  36 DFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRsRIPGKGAFRLVALLPLLAPSLLPA-ISLIYL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  125 DPNAGLFNWLAGligippidwlGNPSTAMASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLP 204
Cdd:TIGR03262 115 FGNQGLLKGLLG----------GFSIYGFWGIVIGEVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLP 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  205 MMKPIILMALFLRMIDAFKSFDLIYVMTRGGPALATEttnMYAYLTGFQDFRISAavVIAIIntLLVIAVLSFASKKVMK 284
Cdd:TIGR03262 185 GAKYGLISAAFVVFTLVITDFGVPKVIGGDYNVLATD---IYKQVIGQQNFPMGA--VVGVL--LLLPALLAFGIDRAIQ 257
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 143-284 6.95e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 51.53  E-value: 6.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  143 IDWLGNPSTAMASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMIDAF 222
Cdd:pfam00528  42 IAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGAL 121

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488141980  223 KSFDLIYVMTRGGPALATETTNMYAYLTGFQDFRISAAVVIAIINTLLVIAVLSFASKKVMK 284
Cdd:pfam00528 122 GGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
23-286 5.07e-91

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 272.01  E-value: 5.07e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  23 FYTLGYAIYLSVHDIDLMSPPPfDFIGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISRDFFGRKLVR 102
Cdd:COG1175   36 LYPLLYTLYLSFTDWNLLGPPP-EFVGLDNYARLFTDPRFWNALGNTLLFTVVSVPLQLVLGLLLALLLNRKLRGRGFFR 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 103 ALLLLPMIVTPIVAGLIWRIFYDPNAGLFNWLAGLIGIPPIDWLGNPSTAMASLILADIWQWTPFIILLVSAGLDALPSE 182
Cdd:COG1175  115 TLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRE 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 183 PLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMIDAFKSFDLIYVMTRGGPALATETTNMYAYLTGFQDFRISAAVV 262
Cdd:COG1175  195 LYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGGGPGNSTTTLVLYIYQTAFQQFDFGYASA 274

                        250       260
                 ....*....|....*....|....
gi 488141980 263 IAIInTLLVIAVLSFASKKVMKDE 286
Cdd:COG1175  275 IAVV-LFLIILVLTLLQLRLLRRR 297
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
47-278 1.14e-29

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 117.18  E-value: 1.14e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  47 FIGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGLIWRIFYD 125
Cdd:COG1178   37 TDGLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARtDFPGRRLLRWLLLLPLALPPYVVALAWIALFG 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 126 PNAGLFNWLAGLIGIPPIDWLGnpstaMASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPM 205
Cdd:COG1178  117 PNGLLNTLLRALFGLEPPDIYG-----LGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPL 191

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488141980 206 MKPIILMALFLRMIDAFKSFDLIYVMTRGGPALATEttnmyAYLTGFQDFRISAAVVIAIIntLLVIAVLSFA 278
Cdd:COG1178  192 LRPAIAAGALLVFLLCLADFGTPLVLGGGYTTLTTA-----IYQAWLGDFDLGAAAALALV--LLLLVLLLLL 257
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 46-282 1.35e-26

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 105.94  E-value: 1.35e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  46 DFIGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFIS--RDFFGRKLVRALLLLPMIVTPIVAGLIWRIF 123
Cdd:COG4209   68 PWVGLKNFKFLFSSPDFWRVLRNTLLISLLKLVFGFPLPIILALLLNelRSKRFKKTVQTISYLPHFLSWVVVAGIVYQF 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 124 YDPNAGLFNWLAGLIGIPPIDWLGNPSTAMASLILADIWQWTPF--IILLvsAGLDALPSEPLEAAELDGARGWRLLAFI 201
Cdd:COG4209  148 LSPDTGLVNQLLRALGGEPINFLTEPKYFRPIYVFSGIWKEAGWgsIIYL--AAITGIDPELYEAAAIDGAGRWQQIWHI 225

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 202 KLPMMKPIILMALFLRMIDAFKS-FDLIYVMTRGGPALATETTNMYAYLTGFQDFRISAAVVI----AIINTLLVIAVlS 276
Cdd:COG4209  226 TLPGIRPTIVILLILNIGNILNVgFEQIYLLYNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVglfkSVVGLILVLIA-N 304


                 ....*.
gi 488141980 277 FASKKV 282
Cdd:COG4209  305 KIAKKL 310
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
27-272 2.93e-25

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 101.44  E-value: 2.93e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  27 GYAIYLSVHDIDlmsppPF----DFIGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISRDFFGRKLVR 102
Cdd:PRK10561  19 GEALWYSLQSVD-----PFgfssQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAALVDYVVRGSRFYQ 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 103 ALLLLPMIVTPIVAGLIWRIFYDPNAGLFNWLAGLIGippIDW--LGNPSTAMASLILADIWQWTPFIILLVSAGLDALP 180
Cdd:PRK10561  94 TLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFG---YDWnhAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIP 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 181 SEPLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMIDA-FKSFDLIYVMTRGGPALATETTNMYAYLTGFQDFRISA 259
Cdd:PRK10561 171 RSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAfFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLSS 250

                        250
                 ....*....|...
gi 488141980 260 AVVIAIINTLLVI 272
Cdd:PRK10561 251 SAAQSVVLMFLVI 263
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 26-286 1.30e-21

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 91.75  E-value: 1.30e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  26 LGYAIYLSVHDIDLMSPPPFDFiGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRAL 104
Cdd:COG1176   30 LLLLLVYSFTTRDPYGGVVPGF-TLENYARLFTDPLYLKVLLRTLWIALLTTLICLLLGYPIAYFLARaPPRWRNLLLLL 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 105 LLLPMIVTPIVAGLIWRIFYDPNaGLFNWLAGLIGI--PPIDWLGNPstamASLILADIWQWTPFIILLVSAGLDALPSE 182
Cdd:COG1176  109 VILPFWTSFLVRTYAWIVLLGRN-GLLNSLLLALGLidEPLRLLYTE----FAVVIGLVYVYLPFMVLPLYAALEKIDPS 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 183 PLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMIDAFKSFDLIYVMtrGGPALATETTNMYAYLTGFQDFRISAAvv 262
Cdd:COG1176  184 LLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALL--GGGKVLMIGNLIYQQFLSALNWPLAAA-- 259

                        250       260
                 ....*....|....*....|....
gi 488141980 263 IAIINTLLVIAVLSFASKKVMKDE 286
Cdd:COG1176  260 LAVVLLLIVLLVLLLYLRLLRRRR 283
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 48-277 4.14e-21

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 89.81  E-value: 4.14e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  48 IGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGLIWRIFYDP 126
Cdd:COG0555   38 LGWAEFWAVLTSPRVLAALKLSLGTALIAALINLVFGLPLAWVLVRyRFPGKRLVDALVDLPFALPTAVAGIALLLLFGP 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 127 NAGLFNWLAGLiGIPPID-WLGnpstamasLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPM 205
Cdd:COG0555  118 NGWLGQLLAPL-GIKVAFtPLG--------IVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPL 188

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488141980 206 MKPIILMAL---FLRMIDAFKSFdliyVMTRGGPALATETTNMYAYLTgFQDFRISAAVVIAIIntLLVIAVLSF 277
Cdd:COG0555  189 LLPALLTGFalaFARALGEFGAV----IFIAGNLPMKTEILPLLIYLK-LEEGDYAGATAIALV--LLLISFLLL 256
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 26-281 1.67e-18

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 82.85  E-value: 1.67e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  26 LGYAIYLSVHDIDLMSPPPFDFiGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRAL 104
Cdd:COG1177   24 ILVLVLYSFNDSWFLTFPPEGF-TLRWYAELFSDPRLLDALLNSLLIALLSTLLATVLGTPAALALARyRFRGRRLLLAL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 105 LLLPMIVTPIVAGLIWRIFYdpnaglfnwlaGLIGIPPidwlgnpstAMASLILADIWQWTPFIILLVSAGLDALPSEPL 184
Cdd:COG1177  103 LLLPLVVPGIVLGVALLLLF-----------SALGLSG---------GLWGLILAHVVFTLPFVVLVVLARLQGFDPSLE 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 185 EAAELDGARGWRLLAFIKLPMMKPIILMALFLrmidAF-KSFDlIYVMTR--GGPALATETTNMYAYLTGFQDFRISAAV 261
Cdd:COG1177  163 EAARDLGASPWQTFRRVTLPLIAPGILAGALL----AFtLSFD-EFVITLflAGPGVTTLPVYIYSMIRRGISPEINALS 237

                        250       260
                 ....*....|....*....|
gi 488141980 262 VIAIINTLLVIAVLSFASKK 281
Cdd:COG1177  238 TLLILLSLLLLLLAERLRRR 257
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 38-275 2.44e-17

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 79.75  E-value: 2.44e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  38 DLMSPPPFDF---IGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVtP 113
Cdd:COG0395   45 EIFSGPPSLLpseFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLAAYALARfRFRGRKLLFLLILATLMI-P 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 114 IVAGLIwrifydPNAGLFNWLagligippiDWLGNpstaMASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGAR 193
Cdd:COG0395  124 GQVLLI------PLYLLFRQL---------GLLNT----YWGLILPYLAFGLPFGIFLLRQFFRSIPRELEEAARIDGAS 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 194 GWRLLAFIKLPMMKPIILMALFLRMIDAFKSFDLIYVMTRgGPALATETTNMYAYLTGFQDF--RISAAVVIAIINTLLV 271
Cdd:COG0395  185 EFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLT-SPDLRTLPVGLASFQGQYGTDwgLLMAAAVIATLPVLIL 263


                 ....
gi 488141980 272 IAVL 275
Cdd:COG0395  264 FLFL 267
malF PRK10999
maltose ABC transporter permease MalF;
47-271 6.94e-16

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 77.31  E-value: 6.94e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  47 FIGMANFIEVL-----QEPRMWSSLWnTLVYVAGSTVAELVLGSAIALFISRDFF-GRKLVRALLLLPMIVTPIVAGLIW 120
Cdd:PRK10999 264 TIGWKNFTRVFtdegiQKPFIAIFIW-TVVFSLLTVVLTVAVGMVLACLVQWEALkGKAVYRVLLILPYAVPSFISILIF 342

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 121 RIFYDPNAGLFN-WLAGLIGIPPiDWLGNPSTAMASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLA 199
Cdd:PRK10999 343 KGLFNQSFGEINmMLSALFGIKP-AWFSDPTLAKTMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFF 421

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 200 FIKLPMM-KPiiLMALflrMIDA----FKSFDLIYVMTRGGPALATETTNM--------YAYLTGF-----QDFRISAAv 261
Cdd:PRK10999 422 KITLPLLiKP--LTPL---MIASfafnFNNFVLIQLLTNGGPDMIGTTTPAgytdllvsYTYRIAFeggggQDFGLAAA- 495

                        250
                 ....*....|
gi 488141980 262 vIAIINTLLV 271
Cdd:PRK10999 496 -IATLIFLLV 504
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
50-281 1.51e-15

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 76.35  E-value: 1.51e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  50 MANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGLIWRIFydpna 128
Cdd:COG1178  324 LDNYRFVLLDPSLLRALLNSLLLALLAALLAVLLALLLAYLVRRrRGRLARLLDRLAMLPYAVPGIVLGLGLLLL----- 398

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 129 glFNWLAGLIgippidwlgnPSTAMASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMMKP 208
Cdd:COG1178  399 --FNRPLPLL----------LYGTLAILVLAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRP 466

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488141980 209 IILMALFLRMIDAFKSFDLIYVMtrGGPALATETTNMYAYLTGFQDFRISAAVVIAIINTLLVIAVLSFASKK 281
Cdd:COG1178  467 GLLAAALLVFVTSMKELSATLLL--RPPGFETLAVLIYQLASSGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 66-272 2.21e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.00  E-value: 2.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  66 LWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGLIWrifydpnaglfnwlaGLIGIPPID 144
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARkRGKLDRLLRRIIDLLLSLPSLVLGLLL---------------VLLFGVLLG 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 145 WLGNPSTAMASLILADIWqWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMIDAFKS 224
Cdd:cd06261   66 WGILPGLGLPALILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGE 144

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 488141980 225 FDLIYVMTRGGPALAteTTNMYAYLTGFQDFRISAAVVIAIINTLLVI 272
Cdd:cd06261  145 FALVSFLGGGEAPGP--GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 46-284 1.57e-11

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 64.32  E-value: 1.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980   46 DFIGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGlIWRIFY 124
Cdd:TIGR03262  36 DFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRsRIPGKGAFRLVALLPLLAPSLLPA-ISLIYL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  125 DPNAGLFNWLAGligippidwlGNPSTAMASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLP 204
Cdd:TIGR03262 115 FGNQGLLKGLLG----------GFSIYGFWGIVIGEVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLP 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  205 MMKPIILMALFLRMIDAFKSFDLIYVMTRGGPALATEttnMYAYLTGFQDFRISAavVIAIIntLLVIAVLSFASKKVMK 284
Cdd:TIGR03262 185 GAKYGLISAAFVVFTLVITDFGVPKVIGGDYNVLATD---IYKQVIGQQNFPMGA--VVGVL--LLLPALLAFGIDRAIQ 257
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 48-273 2.26e-10

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 60.02  E-value: 2.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  48 IGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFIS-RDFFGRKLV-RALLLLPMIVTPIVAGLIwrIFYD 125
Cdd:PRK15050  57 LGLATYRAVLGSPDFRGALLTTLQIAFASTAGCLVLGVLLALVLAfVPFPGASLVgRFIDTFVAFPSFLITLAF--TFLY 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 126 PNAGLFNWLAGLI---GIPPIDWLGNPstamASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIK 202
Cdd:PRK15050 135 GSAGSVNIALQRLfglEAPPLDFLYSP----GGVILAEITFYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVI 210

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488141980 203 LPMMKPIILMALFLRMIDAFKSFDLIYVMTrggpALATETTNMYAYLTGFQDFRISAAVVIAIINTLLVIA 273
Cdd:PRK15050 211 LPEAWPALAAGGSLCLLLTLNEFGIVLFTG----AKDVVTLPVLIYSKAIVDFDYPTACAIAVVNLALSLG 277
cysW PRK11602
sulfate/thiosulfate ABC transporter permease CysW;
49-232 7.51e-09

sulfate/thiosulfate ABC transporter permease CysW;


Pssm-ID: 183225  Cd Length: 283  Bit Score: 55.53  E-value: 7.51e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  49 GMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGLIWRIFYDPN 127
Cdd:PRK11602  49 GLMPVLQNLADPDMLHAIWLTVLIALIAVPVNLVFGILLAWLVTRfNFPGRQLLLTLLDIPFAVSPVVAGLVYLLFYGSN 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 128 AGLFNWLAGLIGIPPIDWLGnpstamasLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMMK 207
Cdd:PRK11602 129 GPLGGWLDEHNLQLMFSWPG--------MVLVTIFVTCPFVVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIR 200

                        170       180
                 ....*....|....*....|....*
gi 488141980 208 PIILMALFLRMIDAFKSFDLIYVMT 232
Cdd:PRK11602 201 WALLYGVVLTNARAIGEFGAVSVVS 225
PhnU TIGR03226
2-aminoethylphosphonate ABC transporter, permease protein; This ABC transporter permease ...
 50-274 7.62e-09

2-aminoethylphosphonate ABC transporter, permease protein; This ABC transporter permease (membrane-spanning) component is found in a region of the salmonella typhimurium LT2 genome responsible for the catabolism of 2-aminoethylphosphonate via the phnWX pathway (GenProp0238).


Pssm-ID: 274484  Cd Length: 288  Bit Score: 55.34  E-value: 7.62e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980   50 MANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIA-LFISRDFFGRKLVRALLLLPMIVTPIVAGLIWRIFYDPNA 128
Cdd:TIGR03226  54 LAAFRQFFASHDFIDALGNTLQIAFAAAGGALVLGSLLAaILFFIPFPGAQLVGRFIDLFIAFPSFLIAFAFIFIYGSAG 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  129 GLFNWLAGLIGI--PPIDWLgnpsTAMASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMM 206
Cdd:TIGR03226 134 LLNGALMAAFAFdaPPLDFL----FGAGGVILAEITFFTPFVMRPLLAGFAQIDKRLLEAASILGAHGLMLARQVIFPAA 209

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488141980  207 KPIILMALFLRMIDAFKSFDLIYVMTRGGpalaTETTNMYAYLTGFQDFRISAAVVIAIINTLLVIAV 274
Cdd:TIGR03226 210 LPAIAAGGILCFLLTLNEFGILLFIGAAG----LITLPMAIYSKAILDIDLPAAAAGALIMIALSLAL 273
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 143-284 6.95e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 51.53  E-value: 6.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  143 IDWLGNPSTAMASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMIDAF 222
Cdd:pfam00528  42 IAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGAL 121

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488141980  223 KSFDLIYVMTRGGPALATETTNMYAYLTGFQDFRISAAVVIAIINTLLVIAVLSFASKKVMK 284
Cdd:pfam00528 122 GGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
48-280 5.73e-07

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 49.75  E-value: 5.73e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  48 IGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGLIWRIFYDP 126
Cdd:PRK10971  42 MSWAQYWEVITNPQVVAAYKVTLLSAFVASIFNAVFGLLMAWILTRyRFPGRTLLDALMDLPFALPTAVAGLTLASLFSV 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 127 NAGLFNWLAGLIGIPPIDWLGnPSTAMASLILadiwqwtPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMM 206
Cdd:PRK10971 122 NGWYGEWLAKFDIKVTYTWLG-IAVAMAFTSI-------PFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPEL 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488141980 207 KPIILMALFLRMIDAFKSFDLIyVMTRGGPALATETTNMYAYLTgFQDFRISAAVVIA----IINTLLVIAVLSFASK 280
Cdd:PRK10971 194 SPALLAGVALSFTRSLGEFGAV-IFIAGNIAWKTEVTSLMIFVR-LQEFDYPAASAIAsvilAASLLLLFSINTLQSR 269
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 45-210 1.75e-06

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 48.22  E-value: 1.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  45 FDFIGMANFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIALFISR-DFFGRK-LVRALLLLPMIvtPIVAGL--IW 120
Cdd:COG3833   54 PENFTLENYKKLFTETPFLRWFLNSLIVAVVTAIISVFLAALAAYAFSRfRFKGRKaGLLALLLLQMF--PAFLALvaLY 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 121 RIFYdpNAGLFNWLAGLIGIppidWLGnpsTAMasliladiwqwtPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAF 200
Cdd:COG3833  132 LLLS--ALGLLNTLLGLILV----YLG---GAI------------PFNTWLMKGYFDTIPKELDEAAKIDGASHFQIFFR 190

                        170
                 ....*....|
gi 488141980 201 IKLPMMKPII 210
Cdd:COG3833  191 IILPLAKPIL 200
thiP TIGR01253
thiamine ABC transporter, permease protein; The model describes thiamine ABC transporter, ...
 64-280 3.62e-05

thiamine ABC transporter, permease protein; The model describes thiamine ABC transporter, permease protein in bacteria. The protein belongs to the larger ABC transport system. It consists of atleast three components: the inner mebrane permease; thiamine binding protein; an ATP-binding subunit. It has been experimentally demonstrated that the mutants in the various steps in the de novo synthesis of the thiamine and the biologically active form, namely thiamine pyrophosphate can be exogenously supplemented with thiamine, thiamine monophosphate (TMP) or thiamine pyrophosphate (TPP). [Transport and binding proteins, Other]


Pssm-ID: 130320 [Multi-domain]  Cd Length: 519  Bit Score: 44.91  E-value: 3.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980   64 SSLWNTLVYVAGSTVAELVLGSAIALFISRDFFGRKLVRALLLLPM----IVTPIVAGLIWRIFYDPNAGLFNWLAGLIG 139
Cdd:TIGR01253  43 DYLQHLILFSFGQAFLSALLSIFFAIFLARALFRKPFLGKKALLKLcaltFILPALVAIFGIIGIYGRQGWLATLANLFG 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  140 IppiDWLGNPsTAMASLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMMKPIILMALFLRMI 219
Cdd:TIGR01253 123 L---EWQFHI-YGLQGILIAHLFFNIPLAAQLFLQALENIPGEQRQLAAQLGLQGWHFFKFVEWPVFRQQCLPTAALIFM 198

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488141980  220 DAFKSFDLIYVMTrGGPALATETTNMYAYLTgfQDFRISAAVVIAIINTLLVIAVLSFASK 280
Cdd:TIGR01253 199 LCFASFATVLSLG-GGPQATTIELAIYQAIL--FDFDLAKAALFALLQFVCCLGLFLLSQR 256
thiP PRK09433
thiamine transporter membrane protein; Reviewed
 52-280 4.21e-04

thiamine transporter membrane protein; Reviewed


Pssm-ID: 181853 [Multi-domain]  Cd Length: 525  Bit Score: 41.36  E-value: 4.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  52 NFIEVLQEPRMWSSLWNTLVYVAGSTVAELVLGSAIAL-FISRDFFGRKLVRALLLLPMIVTPIVA--GLIwRIFydPNA 128
Cdd:PRK09433  32 DWDAVWQDSYLWHVLRFSFWQAFLSALLSVLPAIPLARaLYRRRFPGRGLLLRLCAMTLVLPVLVAvfGLL-SVY--GRS 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 129 GLFNWLAGLIGIP-PIDWLGnpstaMASLILADIWQWTPFIILLVSAGLDALPSEPLE-AAELdGARGWRLLAFIKLPMM 206
Cdd:PRK09433 109 GWLAQLLQALGLEwPFSIYG-----LQGILLAHVFFNLPLATRLLLQALESIPAEQRQlAAQL-GMRGWQFFRLVEWPYL 182

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488141980 207 KPIIL-MALFLRMIdAFKSFDLiyVMTRGG-PALATETTNMYAYLTgFqDFRISAAVVIAIINTLLVIAVLSFASK 280
Cdd:PRK09433 183 RRQLPpVAALIFML-CFTSFAT--VLTLGGgPKATTIELAIYQALS-F-DFDLARAALLALLQMVLCLGLVLLSQR 253
modB PRK09421
molybdate ABC transporter permease subunit;
76-211 1.12e-03

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 39.52  E-value: 1.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  76 STVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGLIWRIFYDPNAGLFNWLAGLIGIP-PIDWLGnpsTAM 153
Cdd:PRK09421  21 AVLFSLPFGILVAWLLARcRFPGKSLLDSLLHLPLVLPPVVTGYLLLISMGRRGFIGQWLYEWFGISfAFSWRG---AAL 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 488141980 154 ASLILAdiwqwTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMMKPIIL 211
Cdd:PRK09421  98 AAAVMA-----FPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGII 150
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 67-225 6.94e-03

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 37.27  E-value: 6.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980  67 WNTLVYVAGSTVAELVLGSAIALFISR-DFFGRKLVRALLLLPMIVTPIVAGLIWRIFYdpnaglfnwlaGLIGIPPIDW 145
Cdd:PRK09500  60 QHSLTMAVFSATFATLIGSLTAVALYRyRFRGKKFVSGMLFVVMMSPDIVMAISLLVLF-----------MLLGIQLGFW 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488141980 146 lgnpstamaSLILADIWQWTPFIILLVSAGLDALPSEPLEAAELDGARGWRLLAFIKLPMMKPII----LMALFLRMIDA 221
Cdd:PRK09500 129 ---------SLLFAHITFCLPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVaagwLLSFTLSLDDV 199


                 ....
gi 488141980 222 FKSF 225
Cdd:PRK09500 200 VVSS 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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