NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|487748523|ref|WP_001830555|]
View 

MULTISPECIES: ABC transporter permease [Staphylococcus]

Protein Classification

ABC transporter permease( domain architecture ID 10003065)

ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of substrates including gylcine betaine, choline, and carnitine

Gene Ontology:  GO:0140359|GO:0042626|GO:0055085|GO:0016020
PubMed:  25750732|24638992|31571164|27273632|26517919|18535149|17723295
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 5-190 8.53e-62

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 191.81  E-value: 8.53e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523   5 LIQQLVHYYQMNFGYLWELFVNHLLMSVYGVLLACLVGIPLGIIIARFGKLSGVIITIANIIQTVPVIAMLAILMLSMGL 84
Cdd:COG1174    1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  85 GMNTVIFTVFLYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFI 164
Cdd:COG1174   81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160

                        170       180
                 ....*....|....*....|....*.
gi 487748523 165 GAPTLGDIVIRGTNATDGTLfILAGA 190
Cdd:COG1174  161 GAGGLGDLIFDGLQLNNTAL-ILAGA 185
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 5-190 8.53e-62

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 191.81  E-value: 8.53e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523   5 LIQQLVHYYQMNFGYLWELFVNHLLMSVYGVLLACLVGIPLGIIIARFGKLSGVIITIANIIQTVPVIAMLAILMLSMGL 84
Cdd:COG1174    1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  85 GMNTVIFTVFLYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFI 164
Cdd:COG1174   81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160

                        170       180
                 ....*....|....*....|....*.
gi 487748523 165 GAPTLGDIVIRGTNATDGTLfILAGA 190
Cdd:COG1174  161 GAGGLGDLIFDGLQLNNTAL-ILAGA 185
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
36-176 3.95e-11

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 61.26  E-value: 3.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  36 LLACLV-GIPLGIIIARFGKLSGVIITIANIIQTVPVIAMLAILMLSMGLGMNTVIFTVFLYALLPIIKNTYTGINEVDP 114
Cdd:PRK10952 157 LLFCIViGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQVPA 236

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 487748523 115 NIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFIGAPTLGDIVIRG 176
Cdd:PRK10952 237 DLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRG 298
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 42-211 2.63e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 54.61  E-value: 2.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523   42 GIPLGIIIA--RFGKLSGVIITIANIIQTVPVIAMLAIL-----MLSMGLGMNTVIFTVFLYALLPIIKNTYTGINEVDP 114
Cdd:pfam00528   1 GIPLGIIAAlrRGRRLDRLLRPLIDLLQALPSFVLAILLvviaiLSILGHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  115 NIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFIGA-PTLGDIVIRGTNATD---GTLFILAGA 190
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSwPGLGLLLIEAILGYDypeIQGPVLAAA 160

                         170       180
                  ....*....|....*....|.
gi 487748523  191 IPIVIIVILIDVLLRLLEKKL 211
Cdd:pfam00528 161 LILLLLNLLVDILQRLLDPRV 181
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 24-190 1.00e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 53.05  E-value: 1.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  24 FVNHLLMSVYGVLLACLVGIPLGIIIARF-GKLSGVIITIANIIQTVPVIAMLAILMLSMGLGMN---------TVIFTV 93
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKrGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilpglglPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  94 FLYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFIGAPTLGDIV 173
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170
                 ....*....|....*..
gi 487748523 174 IRGTNATDGTLFILAGA 190
Cdd:cd06261  161 TGLLLIFAILFPGDLGV 177
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 17-131 5.95e-04

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 39.83  E-value: 5.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523   17 FGYLWELFVNHLLMSVYGVLLACLVGIPLGIIIAR----FGKLSGVIITIANIIQTVPVIAMLAILMLSMGLGMNTVIFT 92
Cdd:TIGR01097  53 LPRILKALLETLAMAILGTVLAAVLAVPLALLAARnitpSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLA 132

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 487748523   93 VFLYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVL 131
Cdd:TIGR01097 133 LAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVI 171
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 5-190 8.53e-62

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 191.81  E-value: 8.53e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523   5 LIQQLVHYYQMNFGYLWELFVNHLLMSVYGVLLACLVGIPLGIIIARFGKLSGVIITIANIIQTVPVIAMLAILMLSMGL 84
Cdd:COG1174    1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  85 GMNTVIFTVFLYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFI 164
Cdd:COG1174   81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160

                        170       180
                 ....*....|....*....|....*.
gi 487748523 165 GAPTLGDIVIRGTNATDGTLfILAGA 190
Cdd:COG1174  161 GAGGLGDLIFDGLQLNNTAL-ILAGA 185
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 21-151 8.42e-23

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 92.52  E-value: 8.42e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  21 WELFVNHLLMSVY----GVLLACLVGIPLGIIIARFGKLSGVIITIANIIQTVPVIAMLAILMLSMGLGMNTVIFTVFLY 96
Cdd:COG0600   56 SGELWEHLLASLLrvllGFALAALLGVPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLG 135

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 487748523  97 ALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIAL 151
Cdd:COG0600  136 AFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIAL 190
ProW COG4176
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 16-189 3.18e-17

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443335  Cd Length: 275  Bit Score: 77.83  E-value: 3.18e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  16 NFGYlWELFVNHLLMSVYGVLLACLVGIPLGIIIARFGKLSGVIITIANIIQTVPVIAMLA-ILMLsMGLGMNTVIFTVF 94
Cdd:COG4176   85 NLGL-WEEAMQTLALVLVAVLIALLIGIPLGILAARSDRVSRIVRPVLDFMQTMPAFVYLIpAVML-FGIGKVPGVIATV 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  95 LYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFIGAPTLGDIVI 174
Cdd:COG4176  163 IFALPPAIRLTNLGIRQVPKELVEAADAFGATPWQLLFKVQLPLALPTIMAGVNQTIMLALSMVVIASMIGAGGLGQEVL 242

                        170
                 ....*....|....*
gi 487748523 175 RGTNATDGTLFILAG 189
Cdd:COG4176  243 RALQRLDIGLGFEAG 257
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
36-176 3.95e-11

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 61.26  E-value: 3.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  36 LLACLV-GIPLGIIIARFGKLSGVIITIANIIQTVPVIAMLAILMLSMGLGMNTVIFTVFLYALLPIIKNTYTGINEVDP 114
Cdd:PRK10952 157 LLFCIViGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQVPA 236

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 487748523 115 NIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFIGAPTLGDIVIRG 176
Cdd:PRK10952 237 DLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRG 298
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 42-211 2.63e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 54.61  E-value: 2.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523   42 GIPLGIIIA--RFGKLSGVIITIANIIQTVPVIAMLAIL-----MLSMGLGMNTVIFTVFLYALLPIIKNTYTGINEVDP 114
Cdd:pfam00528   1 GIPLGIIAAlrRGRRLDRLLRPLIDLLQALPSFVLAILLvviaiLSILGHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  115 NIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFIGA-PTLGDIVIRGTNATD---GTLFILAGA 190
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSwPGLGLLLIEAILGYDypeIQGPVLAAA 160

                         170       180
                  ....*....|....*....|.
gi 487748523  191 IPIVIIVILIDVLLRLLEKKL 211
Cdd:pfam00528 161 LILLLLNLLVDILQRLLDPRV 181
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 24-190 1.00e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 53.05  E-value: 1.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  24 FVNHLLMSVYGVLLACLVGIPLGIIIARF-GKLSGVIITIANIIQTVPVIAMLAILMLSMGLGMN---------TVIFTV 93
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKrGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilpglglPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  94 FLYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFIGAPTLGDIV 173
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170
                 ....*....|....*..
gi 487748523 174 IRGTNATDGTLFILAGA 190
Cdd:cd06261  161 TGLLLIFAILFPGDLGV 177
PRK10160 PRK10160
taurine ABC transporter permease TauC;
20-151 4.17e-08

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 52.09  E-value: 4.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  20 LWELFVNHLLMSVYGVLLACLVGIPLGIIIARFGKLSGVIITIANIIQTVPVIAMLAILMLSMGLGMNTVIFTVFLYALL 99
Cdd:PRK10160  76 LWQHLAASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFA 155

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 487748523 100 PIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIAL 151
Cdd:PRK10160 156 PVAMSALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGL 207
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
18-151 1.11e-07

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 50.70  E-value: 1.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  18 GYLWElfvnHLLMSVYGVLLACLVGIPLGIIIARFGKLSG----VIITIANIIQTVPVIAMLAILMLSMGLGMNTVIFTV 93
Cdd:PRK11365  56 GELWQ----HLAISSWRALIGFSIGGSLGLILGLISGLSRwgerLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLV 131

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 487748523  94 FLYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIAL 151
Cdd:PRK11365 132 ALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRFAL 189
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 16-144 1.43e-05

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 44.30  E-value: 1.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  16 NFGYLWELFVNHLLMSVYGVLLACLVGIPLGII-IARFGKLSGVIITIANIIQTVPVIAMLaiLMLSMGLGMNTVIFTVF 94
Cdd:COG0765   11 YLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALArLSPNPVLRWLATAYVEFFRGTPLLVQL--FFIYFGLPLLGIDLSPF 88

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 487748523  95 LYALLPIIKNT--YT------GINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVII 144
Cdd:COG0765   89 VAAVIALTLNSaaYLaeivraGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIIL 146
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
9-146 2.89e-05

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 44.00  E-value: 2.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523   9 LVHYYQMNF-GYLWELFVNHLLMSVYGVLLACLVGIPLGIIIARF-GKLSGVIITIANIIQTVP--VIAMLAILMLSMGL 84
Cdd:COG1178  324 LDNYRFVLLdPSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRrGRLARLLDRLAMLPYAVPgiVLGLGLLLLFNRPL 403

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 487748523  85 GM---NTVIFTVFLYAL--LPI-IKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGG 146
Cdd:COG1178  404 PLllyGTLAILVLAYVVrfLPFaLRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAA 471
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 3-145 2.20e-04

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 40.83  E-value: 2.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523   3 GNLIQQLVHYYQMNFGYLWELF---VNHLLMSVYGVLLACLVGIPLGIIIAR----FGKLSGVIITIANIIQTVPVIAML 75
Cdd:COG3639   29 PNLADFLSRFFPPDWSYLPDLLsalLETLAIALLGTLLGAVLALPLAFLAARnlapNPWVRLLARRLLNVLRAIPELVWA 108

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523  76 AILMLSMGLGMNTVIFTVFLYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIG 145
Cdd:COG3639  109 LIFVAAVGLGPFAGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLPQVLPQFLS 178
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 17-131 5.95e-04

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 39.83  E-value: 5.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523   17 FGYLWELFVNHLLMSVYGVLLACLVGIPLGIIIAR----FGKLSGVIITIANIIQTVPVIAMLAILMLSMGLGMNTVIFT 92
Cdd:TIGR01097  53 LPRILKALLETLAMAILGTVLAAVLAVPLALLAARnitpSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLA 132

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 487748523   93 VFLYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVL 131
Cdd:TIGR01097 133 LAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVI 171
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 5-102 4.80e-03

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 36.97  E-value: 4.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487748523   5 LIQQLVHYY----QMNFGY-----------LWELFVNHLLMSVYGVLLACLVGIPLGIIIARF--GKLSGVIITIANIIQ 67
Cdd:COG0601   61 LLVQYLDWLggllRGDLGTsfvygrpvsdlIAERLPVTLELALLALLLALLIGIPLGILAALRrgSWLDRLITVLALLGI 140

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 487748523  68 TVP--VIAMLAILMLSMGLG---------MNTVIFTVFLYALLPII 102
Cdd:COG0601  141 SIPsfWLGLLLILLFAVKLGwlpvsgrvsPWEDFLDALRHLILPAL 186
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH