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Conserved domains on  [gi|486269498|ref|WP_001567701|]
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glycosyltransferase family 2 protein [Escherichia coli]

Protein Classification

glycosyltransferase family 2 protein( domain architecture ID 10455355)

glycosyltransferase family 2 protein catalyzes the transfer of saccharide moieties from a donor to an acceptor to form glycosidic bonds

CATH:  3.90.550.10
CAZY:  GT2
EC:  2.4.-.-
Gene Ontology:  GO:0016757|GO:0006486
PubMed:  9445404|10521532|12691742|12200473|10508766
SCOP:  3000077

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 5-112 2.26e-16

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


:

Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 75.89  E-value: 2.26e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498    5 SIVIPTRNRPQYLARVVE-LIASNTCESEVIVADNSDNDSLKDKLKKY-TESGLVKYYYTSENLSVVDNFEKALEKVTGK 82
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLEsLLNQTYPNFEIIVVDDGSTDGTVEIAEEYaKKDPRVRVIRLPENRGKAGARNAGLRAATGD 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 486269498   83 YIIFLGDDDGIGPQ-IENIAHWMDDNHVDAA 112
Cdd:pfam00535  81 YIAFLDADDEVPPDwLEKLVEALEEDGADVV 111
 
Name Accession Description Interval E-value
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 5-112 2.26e-16

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 75.89  E-value: 2.26e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498    5 SIVIPTRNRPQYLARVVE-LIASNTCESEVIVADNSDNDSLKDKLKKY-TESGLVKYYYTSENLSVVDNFEKALEKVTGK 82
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLEsLLNQTYPNFEIIVVDDGSTDGTVEIAEEYaKKDPRVRVIRLPENRGKAGARNAGLRAATGD 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 486269498   83 YIIFLGDDDGIGPQ-IENIAHWMDDNHVDAA 112
Cdd:pfam00535  81 YIAFLDADDEVPPDwLEKLVEALEEDGADVV 111
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 1-134 4.05e-15

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 73.58  E-value: 4.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   1 MAFLSIVIPTRNRPQYLARVVELIASNTCES-EVIVADNSDNDSLKDKLKKYTES-GLVKYYYTSENLSVVDNFEKALEK 78
Cdd:COG0463    1 MPLVSVVIPTYNEEEYLEEALESLLAQTYPDfEIIVVDDGSTDGTAEILRELAAKdPRIRVIRLERNRGKGAARNAGLAA 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 486269498  79 VTGKYIIFLGDDDGIGPQ-IENIAHWMDDNHVDAAFSYSDKFLVNYYWPGVKSKFFD 134
Cdd:COG0463   81 ARGDYIAFLDADDQLDPEkLEELVAALEEGPADLVYGSRLIREGESDLRRLGSRLFN 137
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 6-112 1.69e-12

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 64.83  E-value: 1.69e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   6 IVIPTRNRPQYLARVVE-LIASNTCESEVIVADNSDNDSLKDKLKKYTESG-LVKYYYTSENLSVVDNFEKALEKVTGKY 83
Cdd:cd00761    1 VIIPAYNEEPYLERCLEsLLAQTYPNFEVIVVDDGSTDGTLEILEEYAKKDpRVIRVINEENQGLAAARNAGLKAARGEY 80

                         90       100       110
                 ....*....|....*....|....*....|
gi 486269498  84 IIFLGDDDGIGPQ-IENIAHWMDDNHVDAA 112
Cdd:cd00761   81 ILFLDADDLLLPDwLERLVAELLADPEADA 110
glyco_TIGR04440 TIGR04440
glycosyltransferase domain; This model describes a putative glycotransferase domain, related ...
 4-107 3.81e-12

glycosyltransferase domain; This model describes a putative glycotransferase domain, related to the group 2 family glycosyltransferases of pfam00535.


Pssm-ID: 275233  Cd Length: 215  Bit Score: 65.01  E-value: 3.81e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498    4 LSIVIPTRNRPQYLARVVELIASNTCESEVIVADNSDNDSLKDKLKKYTESGLVKYYYTSENLSVVDNFEK---ALEKVT 80
Cdd:TIGR04440   2 LTIIIPTYNRPEYLKRWLRYYSDFGCDYRIIIADSSDEKFNENNLKVFKNYSNPNITYLHYPDLGVPFYEKlldALEQVE 81

                          90       100
                  ....*....|....*....|....*...
gi 486269498   81 GKYIIFLGDDDGIGPQ-IENIAHWMDDN 107
Cdd:TIGR04440  82 TPYVVICADDDFIIPSgLTECLSFLEAN 109
PRK10018 PRK10018
colanic acid biosynthesis glycosyltransferase WcaA;
3-145 9.07e-03

colanic acid biosynthesis glycosyltransferase WcaA;


Pssm-ID: 182197 [Multi-domain]  Cd Length: 279  Bit Score: 37.66  E-value: 9.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   3 FLSIVIPTRNRPQYLARVVELIASNTCES-EVIVADnsDNDSLKDKLKKYTES---GLVKYYYTSENLSVVDNFEKALEK 78
Cdd:PRK10018   6 LISIYMPTWNRQQLAIRAIKSVLRQDYSNwEMIIVD--DCSTSWEQLQQYVTAlndPRITYIHNDINSGACAVRNQAIML 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498  79 VTGKYIIFLGDDDGIGPQIENIAHWMDDNHVDAAFSYSDKFLVN---YYWPGVKSKFFDDKYSSRIFISK 145
Cdd:PRK10018  84 AQGEYITGIDDDDEWTPNRLSVFLAHKQQLVTHAFLYANDYVCQgevYSQPASLPLYPKSPYSRRLFYKR 153
 
Name Accession Description Interval E-value
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 5-112 2.26e-16

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 75.89  E-value: 2.26e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498    5 SIVIPTRNRPQYLARVVE-LIASNTCESEVIVADNSDNDSLKDKLKKY-TESGLVKYYYTSENLSVVDNFEKALEKVTGK 82
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLEsLLNQTYPNFEIIVVDDGSTDGTVEIAEEYaKKDPRVRVIRLPENRGKAGARNAGLRAATGD 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 486269498   83 YIIFLGDDDGIGPQ-IENIAHWMDDNHVDAA 112
Cdd:pfam00535  81 YIAFLDADDEVPPDwLEKLVEALEEDGADVV 111
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 1-134 4.05e-15

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 73.58  E-value: 4.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   1 MAFLSIVIPTRNRPQYLARVVELIASNTCES-EVIVADNSDNDSLKDKLKKYTES-GLVKYYYTSENLSVVDNFEKALEK 78
Cdd:COG0463    1 MPLVSVVIPTYNEEEYLEEALESLLAQTYPDfEIIVVDDGSTDGTAEILRELAAKdPRIRVIRLERNRGKGAARNAGLAA 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 486269498  79 VTGKYIIFLGDDDGIGPQ-IENIAHWMDDNHVDAAFSYSDKFLVNYYWPGVKSKFFD 134
Cdd:COG0463   81 ARGDYIAFLDADDQLDPEkLEELVAALEEGPADLVYGSRLIREGESDLRRLGSRLFN 137
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
1-91 6.54e-14

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 70.02  E-value: 6.54e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   1 MAFLSIVIPTRNRPQYLARVVELIASNTCES-EVIVADNSDNDSLKDKLKKYTESGlVKYYYTSENLSVVDNFEKALEKV 79
Cdd:COG1216    2 RPKVSVVIPTYNRPELLRRCLESLLAQTYPPfEVIVVDNGSTDGTAELLAALAFPR-VRVIRNPENLGFAAARNLGLRAA 80

                         90
                 ....*....|..
gi 486269498  80 TGKYIIFLGDDD 91
Cdd:COG1216   81 GGDYLLFLDDDT 92
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 6-112 1.69e-12

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 64.83  E-value: 1.69e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   6 IVIPTRNRPQYLARVVE-LIASNTCESEVIVADNSDNDSLKDKLKKYTESG-LVKYYYTSENLSVVDNFEKALEKVTGKY 83
Cdd:cd00761    1 VIIPAYNEEPYLERCLEsLLAQTYPNFEVIVVDDGSTDGTLEILEEYAKKDpRVIRVINEENQGLAAARNAGLKAARGEY 80

                         90       100       110
                 ....*....|....*....|....*....|
gi 486269498  84 IIFLGDDDGIGPQ-IENIAHWMDDNHVDAA 112
Cdd:cd00761   81 ILFLDADDLLLPDwLERLVAELLADPEADA 110
glyco_TIGR04440 TIGR04440
glycosyltransferase domain; This model describes a putative glycotransferase domain, related ...
 4-107 3.81e-12

glycosyltransferase domain; This model describes a putative glycotransferase domain, related to the group 2 family glycosyltransferases of pfam00535.


Pssm-ID: 275233  Cd Length: 215  Bit Score: 65.01  E-value: 3.81e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498    4 LSIVIPTRNRPQYLARVVELIASNTCESEVIVADNSDNDSLKDKLKKYTESGLVKYYYTSENLSVVDNFEK---ALEKVT 80
Cdd:TIGR04440   2 LTIIIPTYNRPEYLKRWLRYYSDFGCDYRIIIADSSDEKFNENNLKVFKNYSNPNITYLHYPDLGVPFYEKlldALEQVE 81

                          90       100
                  ....*....|....*....|....*...
gi 486269498   81 GKYIIFLGDDDGIGPQ-IENIAHWMDDN 107
Cdd:TIGR04440  82 TPYVVICADDDFIIPSgLTECLSFLEAN 109
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 1-112 1.39e-11

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 64.76  E-value: 1.39e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   1 MAFLSIVIPTRNRPQYLARVVELIASNTCES---EVIVADNSDNDSLKDKLKKYTESGL-VKYYYTSENLSVVDNFEKAL 76
Cdd:COG1215   28 LPRVSVIIPAYNEEAVIEETLRSLLAQDYPKeklEVIVVDDGSTDETAEIARELAAEYPrVRVIERPENGGKAAALNAGL 107

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 486269498  77 EKVTGKYIIFLGDDDGIGPQ-IENIAHWMDDNHVDAA 112
Cdd:COG1215  108 KAARGDIVVFLDADTVLDPDwLRRLVAAFADPGVGAS 144
GT2_RfbC_Mx_like cd04184
Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene ...
 4-118 1.19e-09

Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133027 [Multi-domain]  Cd Length: 202  Bit Score: 57.60  E-value: 1.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   4 LSIVIPTRNRPQ-YLARVVELIASNTCES-EV-IVADNSDNDSLKDKLKKYTES-GLVKYYYTSENLSVVDNFEKALEKV 79
Cdd:cd04184    3 ISIVMPVYNTPEkYLREAIESVRAQTYPNwELcIADDASTDPEVKRVLKKYAAQdPRIKVVFREENGGISAATNSALELA 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 486269498  80 TGKYIIFLGDDDGIGPQ--IENIAHWMDDNhvDAAFSYSDK 118
Cdd:cd04184   83 TGEFVALLDHDDELAPHalYEVVKALNEHP--DADLIYSDE 121
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 6-90 2.72e-07

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 49.87  E-value: 2.72e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   6 IVIPTRNRPQYLARVVE-LIASNTCESEVIVADNSDNDSLKDKLKKYteSGLVKYYYTSENLSVVDNFEKALEKVTGKYI 84
Cdd:cd04186    1 IIIVNYNSLEYLKACLDsLLAQTYPDFEVIVVDNASTDGSVELLREL--FPEVRLIRNGENLGFGAGNNQGIREAKGDYV 78


                 ....*.
gi 486269498  85 IFLGDD 90
Cdd:cd04186   79 LLLNPD 84
GT_2_WfgS_like cd06433
WfgS and WfeV are involved in O-antigen biosynthesis; Escherichia coli WfgS and Shigella ...
 5-91 2.83e-07

WfgS and WfeV are involved in O-antigen biosynthesis; Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133055 [Multi-domain]  Cd Length: 202  Bit Score: 50.62  E-value: 2.83e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   5 SIVIPTRNRPQYLARVVELIASNTCES-EVIVAD-NSDNDSLkDKLKKYtesGLVKYYYTSENlsvvDN-----FEKALE 77
Cdd:cd06433    1 SIITPTYNQAETLEETIDSVLSQTYPNiEYIVIDgGSTDGTV-DIIKKY---EDKITYWISEP----DKgiydaMNKGIA 72

                         90
                 ....*....|....
gi 486269498  78 KVTGKYIIFLGDDD 91
Cdd:cd06433   73 LATGDIIGFLNSDD 86
GT2_Chondriotin_Pol_N cd06420
N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Chondroitin ...
 6-89 5.88e-05

N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Chondroitin polymerase is a two domain, bi-functional protein. The N-terminal domain functions as a GalNAc transferase. The bacterial chondroitin polymerase catalyzes elongation of the chondroitin chain by alternatively transferring the GlcUA and GalNAc moiety from UDP-GlcUA and UDP-GalNAc to the non-reducing ends of the chondroitin chain. The enzyme consists of N-terminal and C-terminal domains in which the two active sites catalyze the addition of GalNAc and GlcUA, respectively. Chondroitin chains range from 40 to over 100 repeating units of the disaccharide. Sulfated chondroitins are involved in the regulation of various biological functions such as central nervous system development, wound repair, infection, growth factor signaling, and morphogenesis, in addition to its conventional structural roles. In Caenorhabditis elegans, chondroitin is an essential factor for the worm to undergo cytokinesis and cell division. Chondroitin is synthesized as proteoglycans, sulfated and secreted to the cell surface or extracellular matrix.


Pssm-ID: 133042 [Multi-domain]  Cd Length: 182  Bit Score: 43.34  E-value: 5.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   6 IVIPTRNRPQYLARVVELIASNTC-ESEVIVADNSDNDSLKDKLKKYTESGLVKYYYT-SEN----LSVVDNfeKALEKV 79
Cdd:cd06420    1 LIITTYNRPEALELVLKSVLNQSIlPFEVIIADDGSTEETKELIEEFKSQFPIPIKHVwQEDegfrKAKIRN--KAIAAA 78

                         90
                 ....*....|.
gi 486269498  80 TGKYIIFL-GD 89
Cdd:cd06420   79 KGDYLIFIdGD 89
GT_2_like_b cd04185
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 7-115 5.34e-03

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133028 [Multi-domain]  Cd Length: 202  Bit Score: 37.61  E-value: 5.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   7 VIPTRNRPQYLARVVELIASNTCE-SEVIVADNSDNDSLKDKLKKYTESGLVKYYYTSENLSVVDNFEKALEKV--TGKY 83
Cdd:cd04185    2 VVVTYNRLDLLKECLDALLAQTRPpDHIIVIDNASTDGTAEWLTSLGDLDNIVYLRLPENLGGAGGFYEGVRRAyeLGYD 81

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 486269498  84 IIFLGDDDGIgP---QIENIAHWMDDNHVDAAFSY 115
Cdd:cd04185   82 WIWLMDDDAI-PdpdALEKLLAYADKDNPQFLAPL 115
PRK10018 PRK10018
colanic acid biosynthesis glycosyltransferase WcaA;
3-145 9.07e-03

colanic acid biosynthesis glycosyltransferase WcaA;


Pssm-ID: 182197 [Multi-domain]  Cd Length: 279  Bit Score: 37.66  E-value: 9.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498   3 FLSIVIPTRNRPQYLARVVELIASNTCES-EVIVADnsDNDSLKDKLKKYTES---GLVKYYYTSENLSVVDNFEKALEK 78
Cdd:PRK10018   6 LISIYMPTWNRQQLAIRAIKSVLRQDYSNwEMIIVD--DCSTSWEQLQQYVTAlndPRITYIHNDINSGACAVRNQAIML 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486269498  79 VTGKYIIFLGDDDGIGPQIENIAHWMDDNHVDAAFSYSDKFLVN---YYWPGVKSKFFDDKYSSRIFISK 145
Cdd:PRK10018  84 AQGEYITGIDDDDEWTPNRLSVFLAHKQQLVTHAFLYANDYVCQgevYSQPASLPLYPKSPYSRRLFYKR 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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