|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
4-465 |
0e+00 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 767.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 4 IRLHKDAAATWLSRLLPAAIFILVGLFSIMVIRDYGRESAAARQTLLEKGNVLIRALESGTRVGMGMRMHHAQQQTLLEE 83
Cdd:PRK10364 1 MQRSKDSLAKWLSALLPVVIVGLVGLFSVTVIRDYGRETAAARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 84 MAGQPGVLWFAVTDAQGVIITHSNPGMVGKSLYSASEMHQLNPGPQERWRRVDvAANGEtvPALEIYRQFQPLFGMRGHG 163
Cdd:PRK10364 81 MAGQPGVRWFAVTDEQGTIVAHSNPGMVGKQLYSPQEMQQLHPGDEEAWRRID-SADGE--PVLEIYRQFQPMFAAGMHG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 164 MRGHGMARSAnddePAKQTIFIAFDASELAATQAREWRNTLIVLSALAAVLLATLLAFFWHQRYQRSHRELLDAMKRKEK 243
Cdd:PRK10364 158 MRHMQQYAAA----NTPQAIFIAFDASNLVSAQAREQRNTLIILFALATVLLASLLAFFWYRRYLRSRQLLQDEMKRKEK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 244 LVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPAGGESHELAQVMAKEADRLNRVVSELLELVKPAHLTLQTVNLNDII 323
Cdd:PRK10364 234 LVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNDLI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 324 THSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGtDRVIITVTDSGKGI 403
Cdd:PRK10364 314 NHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESG-AGVKISVTDSGKGI 392
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 486168906 404 APDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPVIARQQD 465
Cdd:PRK10364 393 AADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPVNITRRD 454
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
231-465 |
1.12e-82 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 259.39 E-value: 1.12e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 231 HRELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPAGgESHELAQVMAKEADRLNRVVSELLELVKPA 310
Cdd:COG3852 119 RKRLERELRRAEKLAAVGELAAGLAHEIRNPLTGIRGAAQLLERELPDD-ELREYTQLIIEEADRLNNLVDRLLSFSRPR 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 311 HLTLQTVNLNDIITHSLNLVSQDAQSReIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISV-------- 382
Cdd:COG3852 198 PPEREPVNLHEVLERVLELLRAEAPKN-IRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIrtrverqv 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 383 -EAKESGTDRVIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPVIA 461
Cdd:COG3852 277 tLGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLPLEQ 356
|
....
gi 486168906 462 RQQD 465
Cdd:COG3852 357 AEEE 360
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
237-464 |
1.84e-76 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 245.26 E-value: 1.84e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 237 AMKRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPAGGES-----HELAQVMAKEADRLNRVVSELLELVKPAH 311
Cdd:COG5000 191 ELLRAERLAAWGELARRIAHEIKNPLTPIQLSAERLRRKLADKLEEdredlERALDTIIRQVDRLKRIVDEFLDFARLPE 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 312 LTLQTVNLNDIITHSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGtDR 391
Cdd:COG5000 271 PQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRRED-GR 349
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 486168906 392 VIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPVIARQQ 464
Cdd:COG5000 350 VRIEVSDNGPGIPEEVLERIFEPFFTTKPKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPLAEEAE 422
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
225-459 |
7.96e-76 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 241.63 E-value: 7.96e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 225 QRYQRSHRELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKG---LAKYFAERTPAGGESHELAQVMAKEADRLNRVVS 301
Cdd:COG4191 120 ERAEEELRELQEQLVQSEKLAALGELAAGIAHEINNPLAAILGnaeLLRRRLEDEPDPEELREALERILEGAERAAEIVR 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 302 ELLELVKPAHLTLQTVNLNDIITHSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAI--GRQGT 379
Cdd:COG4191 200 SLRAFSRRDEEEREPVDLNELIDEALELLRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIDAMeeGEGGR 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 380 ISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYFTTKA--DGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWL 457
Cdd:COG4191 280 ITISTRREG-DYVVISVRDNGPGIPPEVLERIFEPFFTTKPvgKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITL 358
|
..
gi 486168906 458 PV 459
Cdd:COG4191 359 PL 360
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
231-459 |
4.25e-73 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 241.41 E-value: 4.25e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 231 HRELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKyFAERTPAGGESHELAQVMAKEADRLNRVVSELLELVKPA 310
Cdd:PRK11360 374 RKRLQRRVARQERLAALGELVAGVAHEIRNPLTAIRGYVQ-IWRQQTSDPPSQEYLSVVLREVDRLNKVIDQLLEFSRPR 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 311 HLTLQTVNLNDIITHSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGTD 390
Cdd:PRK11360 453 ESQWQPVSLNALVEEVLQLFQTAGVQARVDFETELDNELPPIWADPELLKQVLLNILINAVQAISARGKIRIRTWQYSDG 532
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 486168906 391 RVIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:PRK11360 533 QVAVSIEDNGCGIDPELLKKIFDPFFTTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLPI 601
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
232-459 |
9.84e-70 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 229.48 E-value: 9.84e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 232 RELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERtpAGGESHELAQVMAKEADRLNRVVSELLELVKPAH 311
Cdd:COG5809 255 KKLEELLRKSEKLSVVGELAAGIAHEIRNPLTSLKGFIQLLKDT--IDEEQKTYLDIMLSELDRIESIISEFLVLAKPQA 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 312 LTLQTVNLNDIITHSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGTDR 391
Cdd:COG5809 333 IKYEPKDLNTLIEEVIPLLQPQALLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIEAMPEGGNITIETKAEDDDK 412
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 486168906 392 VIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:COG5809 413 VVISVTDEGCGIPEERLKKLGEPFYTTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLPI 480
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
169-459 |
6.13e-64 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 209.76 E-value: 6.13e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 169 MARSANDDEPAKQTIFIAFDASELAATQAREWRNTLIVLSALAAVLLATLLAFFWHQRYQRSHRELLDAMKRKEKLVAMG 248
Cdd:COG0642 32 LALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLEEANEAKS 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 249 HLAAGVAHEIRNPLSSIKGLAKYFAERTPAggESHELAQVMAKEADRLNRVVSELLELVK----PAHLTLQTVNLNDIIT 324
Cdd:COG0642 112 RFLANVSHELRTPLTAIRGYLELLLEELDE--EQREYLETILRSADRLLRLINDLLDLSRleagKLELEPEPVDLAELLE 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 325 HSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGtDRVIITVTDSGKGIA 404
Cdd:COG0642 190 EVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRREG-DRVRISVEDTGPGIP 268
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 486168906 405 PDQLEAIFTPYFTTKAD----GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:COG0642 269 PEDLERIFEPFFRTDPSrrggGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTLPL 327
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
115-459 |
1.01e-61 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 205.94 E-value: 1.01e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 115 LYSASEMHQLNPGPQERWRRVDVAANGETVPALEIYRQFQPLFGMRGHGMRGHGMARSANDDEPAKQTIFIAFDASELAA 194
Cdd:COG5002 39 LLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALL 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 195 TQAREWRNTLIVLSALAAVLLATLLAFFWHQRYQRSHRELLDAMKRKEKLVAMghlaagVAHEIRNPLSSIKG---LAKY 271
Cdd:COG5002 119 LLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRREFVAN------VSHELRTPLTSIRGyleLLLD 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 272 FAERTPAggESHELAQVMAKEADRLNRVVSELLELVK----PAHLTLQTVNLNDIITHSLNLVSQDAQSREIQLRFTANE 347
Cdd:COG5002 193 GAADDPE--ERREYLEIILEEAERLSRLVNDLLDLSRlesgELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPE 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 348 TLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYFTT------KAD 421
Cdd:COG5002 271 DPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREED-DQVRISVRDTGIGIPEEDLPRIFERFYRVdksrsrETG 349
|
330 340 350
....*....|....*....|....*....|....*...
gi 486168906 422 GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:COG5002 350 GTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLPL 387
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
240-460 |
1.63e-61 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 204.25 E-value: 1.63e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 240 RKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPaGGESHELAQVMAKEADRLNRVVSELLELVKPAHLTLQTVNL 319
Cdd:COG5807 140 RSEKLSVAGELAAGIAHEIRNPLTSIKGFLQLLQESRE-DSEREEYFNIIISEIDRINTIITELLVLSKPKKFNFKKLNL 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 320 NDIITHSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGtDRVIITVTDS 399
Cdd:COG5807 219 NDVLEDVIALLSTEAILKNISIKYDLADDEPVINGDKNQLKQVFINLIKNAIEAMETGGNITIKTYVEG-DFVVISVKDE 297
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 486168906 400 GKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPVI 460
Cdd:COG5807 298 GIGIPEEVLEKIGEPFFTTKEEGTGLGLSICKKIIEEHNGTIEVESKPGKGTTFTIYLPLY 358
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
228-461 |
1.06e-60 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 198.21 E-value: 1.06e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 228 QRSHRELLDAMKRKEKLVAMghlaagVAHEIRNPLSSIKGLAKYFAERTPAGGES-HELAQVMAKEADRLNRVVSELLEL 306
Cdd:COG2205 3 EEALEELEELERLKSEFLAN------VSHELRTPLTSILGAAELLLDEEDLSPEErRELLEIIRESAERLLRLIEDLLDL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 307 VK----PAHLTLQTVNLNDIITHSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISV 382
Cdd:COG2205 77 SRlesgKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 383 EAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYF----TTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:COG2205 157 SARREG-DGVRISVSDNGPGIPEEELERIFERFYrgdnSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLP 235
|
...
gi 486168906 459 VIA 461
Cdd:COG2205 236 LAE 238
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
238-459 |
2.34e-60 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 204.97 E-value: 2.34e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 238 MKRKEKLVAMGHLAAGVAHEIRNPLSSIKGlakyFAERTPAGGES-HELAQVMAKEADRLNRVVSELLELVKPAHLTLQT 316
Cdd:COG5805 278 MARSEKLSIAGQLAAGIAHEIRNPLTSIKG----FLQLLQPGIEDkEEYFDIMLSELDRIESIISEFLALAKPQAVNKEK 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 317 VNLNDIITHSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGTDrVIITV 396
Cdd:COG5805 354 ENINELIQDVVTLLETEAILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNS-VIIRV 432
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 486168906 397 TDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:COG5805 433 IDEGIGIPEERLKKLGEPFFTTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPL 495
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
229-459 |
7.93e-57 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 193.55 E-value: 7.93e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 229 RSHRELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPAGGESHELAQVMAKEADRLNRVVSELLELVK 308
Cdd:COG5806 183 IENILLRKELQRAEKLEVVSELAASIAHEVRNPLTVVRGFIQLLQEPELSDEKRKQYIRIALEELDRAEAIITDYLTFAK 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 309 PAHLTLQTVNLNDIITHSLNLVSQDAQSREIQLRFTANETLKrIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESG 388
Cdd:COG5806 263 PQPEKLEKIDVSEELEHVIDVLSPYANMNNVEIQTELEPGLY-IEGDRQKLQQCLINIIKNGIEAMPNGGTLTIDVSIDK 341
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 486168906 389 tDRVIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:COG5806 342 -NKVIISIKDTGVGMTKEQLERLGEPYFSTKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTTFTITLPL 411
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
222-461 |
2.76e-53 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 185.34 E-value: 2.76e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 222 FWHQRYQRSHRELLDAMKRKeKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPaGGESHELAQVMAKEADRLNRVVS 301
Cdd:COG5808 217 YNLLKRKTLLERVIQEINTQ-KLELIGTFAASTAHEIRNPLTSIKGFIQLLQEKYP-ELEDQKYFDIIQEEIQRINQIVS 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 302 ELLELVKPAHLTLQTVNLNDIITHSLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTIS 381
Cdd:COG5808 295 EFLVLGKPTAKKLELDDLNELIEEILSIIDSEANLKNIRVEKQSLDEPLHIKCDKDRIKQVLLNLIKNAIEAMKEGGKLT 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 382 VEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPVIA 461
Cdd:COG5808 375 ISIENDD-EKAVIEVIDNGEGIPEDIIDEIFEPFVTTKEGGTGLGLSVCKRIVEMHGGEIDIESEEGKGTTFTIRLPLKK 453
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
1-459 |
3.96e-39 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 148.01 E-value: 3.96e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 1 MSFIRLHKDAAATWLSRLLPAAIFILVGLFSIMVIRDYGRESAAARQTLLEKGNVLIRALESGTRVGMGMRMHHAQQQTL 80
Cdd:COG4251 56 LSLLALLLLLLLLLLLLLVLAALALLLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 81 LEEMAGQPGVLWFAVTDAQGVIITHSNPGMVGKSLYSASEMHQLNPGPQERWRRVDVAANGETVPALEIYRQFQPLFGMR 160
Cdd:COG4251 136 LLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEA 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 161 GHGMRGHGMARSANDDEPAKQTIFIAFDASELAATQAREWRNTLIVLSALaavllatllaffwhQRYQRSHRELLDAMKR 240
Cdd:COG4251 216 ELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELE--------------EELEERTAELERSNEE 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 241 KEklvamgHLAAGVAHEIRNPLSSIKGLAKYFAERTPA--GGESHELAQVMAKEADRLNRVVSELLEL--VKPAHLTLQT 316
Cdd:COG4251 282 LE------QFAYVASHDLREPLRKISGFSQLLEEDYGDklDEEGREYLERIRDAAERMQALIDDLLAYsrVGRQELEFEP 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 317 VNLNDIITHSLNLVSQDAQSREIQLRFtanETLKRIQADPDRLTQVLLNLYLNAI--HAIGRQGTISVEAKESGtDRVII 394
Cdd:COG4251 356 VDLNELLEEVLEDLEPRIEERGAEIEV---GPLPTVRGDPTLLRQVFQNLISNAIkySRPGEPPRIEIGAEREG-GEWVF 431
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 486168906 395 TVTDSGKGIAPDQLEAIFTPYFT----TKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:COG4251 432 SVRDNGIGIDPEYAEKIFEIFQRlhsrDEYEGTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTLPK 500
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
225-463 |
4.96e-38 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 147.52 E-value: 4.96e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 225 QRYQRSHRELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPAGGESHELAQVMAKEADRLNRVVSELL 304
Cdd:PRK13837 428 RRLETERDALERRLEHARRLEAVGTLASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGARARLIIDQIL 507
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 305 ELVKPAHLTLQTVNLNDIITHSLNLVSQDAQSR-EIQLRFTANETlkRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVE 383
Cdd:PRK13837 508 AFGRKGERNTKPFDLSELVTEIAPLLRVSLPPGvELDFDQDQEPA--VVEGNPAELQQVLMNLCSNAAQAMDGAGRVDIS 585
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 384 AK----------ESGT----DRVIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGK 449
Cdd:PRK13837 586 LSraklrapkvlSHGVlppgRYVLLRVSDTGAGIDEAVLPHIFEPFFTTRAGGTGLGLATVHGIVSAHAGYIDVQSTVGR 665
|
250
....*....|....
gi 486168906 450 GAVFTIWLPVIARQ 463
Cdd:PRK13837 666 GTRFDVYLPPSSKV 679
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
354-459 |
8.53e-36 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 128.15 E-value: 8.53e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 354 ADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYFTTKAD-----GTGLGLA 428
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDG-DHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRsrkigGTGLGLS 79
|
90 100 110
....*....|....*....|....*....|.
gi 486168906 429 VVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:smart00387 80 IVKKLVELHGGEISVESEPGGGTTFTITLPL 110
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
356-459 |
1.15e-35 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 127.54 E-value: 1.15e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 356 PDRLTQVLLNLYLNAIHAIGRQGTISVEAKESgTDRVIITVTDSGKGIAPDQLEAIFTPYFTTK--ADGTGLGLAVVQNI 433
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAMEGRGRITIRTWAH-VDQVLIEVEDTGSGIDPEILGRIFDPFFTTKpvGEGTGLGLSLSYRI 79
|
90 100
....*....|....*....|....*.
gi 486168906 434 IEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:cd16943 80 IQKHGGTIRVASVPGGGTRFTIILPI 105
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
255-458 |
8.98e-32 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 125.35 E-value: 8.98e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 255 AHEIRNPLSSIKGLAKyfaertpaGGESHELAQVMAKEADRLNRVVSELLELVKPAHLtlqtvnlnDIIthsLNLVSQDA 334
Cdd:COG3290 197 RHDFRNHLHTISGLLQ--------LGEYDEALEYIDEISEELQELIDSLLSRIGNPVL--------AAL---LLGKAARA 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 335 QSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQ----GTISVEAKESGtDRVIITVTDSGKGIAPDQLEA 410
Cdd:COG3290 258 RERGIDLTIDIDSDLPDLPLSDTDLVTILGNLLDNAIEAVEKLpeeeRRVELSIRDDG-DELVIEVEDSGPGIPEELLEK 336
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 486168906 411 IFTPYFTTKA-DGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:COG3290 337 IFERGFSTKLgEGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLP 385
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
354-459 |
2.34e-30 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 113.62 E-value: 2.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 354 ADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESgtDRVIITVTDSGKGIAPDQLEAIFTPYFT---TKADGTGLGLAVV 430
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSEG--GELTLTVEDNGIGIPPEDLPRIFEPFSTadkRGGGGTGLGLSIV 78
|
90 100
....*....|....*....|....*....
gi 486168906 431 QNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:pfam02518 79 RKLVELLGGTITVESEPGGGTTVTLTLPL 107
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
359-457 |
2.70e-30 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 113.08 E-value: 2.70e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHAIGRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYFTTKAD----GTGLGLAVVQNII 434
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEG-DGVVLEVEDNGPGIPEEDLERIFERFYRGDKSreggGTGLGLAIVRRIV 79
|
90 100
....*....|....*....|...
gi 486168906 435 EQHGGAIKVKSIEGKGAVFTIWL 457
Cdd:cd00075 80 EAHGGRITVESEPGGGTTFTVTL 102
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
245-459 |
1.25e-27 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 112.87 E-value: 1.25e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 245 VAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPaGGESHELAQVMAKEADRLNRVVSELLELVKPAhlTLQTVNLNDIIT 324
Cdd:PRK11073 128 VAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP-DPALTEYTKVIIEQADRLRNLVDRLLGPQRPG--THVTESIHKVAE 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 325 HSLNLVSQDAQSrEIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQ-GTISVEAKesgTDRVI---------- 393
Cdd:PRK11073 205 RVVQLVSLELPD-NVRLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEgGTITLRTR---TAFQLtlhgeryrla 280
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 486168906 394 --ITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKgAVFTIWLPV 459
Cdd:PRK11073 281 arIDIEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTSWPGH-TEFSVYLPI 347
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
255-461 |
2.26e-27 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 114.17 E-value: 2.26e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 255 AHEIRNPLSSIKGLAKYFAERTPAGGESHELAQVMAkEADRLNRVVSELLELVK----PAHLTLQTVNLNDIITHSLNLV 330
Cdd:PRK11100 264 THELKSPLAAIRGAAELLQEDPPPEDRARFTGNILT-QSARLQQLIDRLLELARleqrQELEVLEPVALAALLEELVEAR 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 331 SQDAQSREIQLRFTANETlkRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAkESGTDRVIITVTDSGKGIaPD-QLE 409
Cdd:PRK11100 343 EAQAAAKGITLRLRPDDA--RVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSA-EVDGEQVALSVEDQGPGI-PDyALP 418
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 486168906 410 AIF-----TPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPVIA 461
Cdd:PRK11100 419 RIFerfysLPRPANGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPRHF 475
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-458 |
2.50e-27 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 105.17 E-value: 2.50e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHAI------GRQGTISVEakESGTDRVIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQN 432
Cdd:cd16920 1 IQQVLINLVRNGIEAMseggceRRELTIRTS--PADDRAVTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICRS 78
|
90 100
....*....|....*....|....*.
gi 486168906 433 IIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:cd16920 79 IIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
233-459 |
3.92e-26 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 109.27 E-value: 3.92e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 233 ELLDAMKRKEKLVAMghlaagVAHEIRNPLS-------SIK-GLAKYFAERTPAGGESheLAQVMAKEADRLNRVVSELL 304
Cdd:PRK09303 143 TLLEQLKFKDRVLAM------LAHDLRTPLTaaslaleTLElGQIDEDTELKPALIEQ--LQDQARRQLEEIERLITDLL 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 305 ELVKPAHLTLQtvnlndIITHSLNL--VSQDA--------QSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAI 374
Cdd:PRK09303 215 EVGRTRWEALR------FNPQKLDLgsLCQEVilelekrwLAKSLEIQTDIPSDLPSVYADQERIRQVLLNLLDNAIKYT 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 375 GRQGTISVEAKESGTDRVIITVTDSGKGIAPDQLEAIFTPYFTTKAD----GTGLGLAVVQNIIEQHGGAIKVKSIEGKG 450
Cdd:PRK09303 289 PEGGTITLSMLHRTTQKVQVSICDTGPGIPEEEQERIFEDRVRLPRDegteGYGIGLSVCRRIVRVHYGQIWVDSEPGQG 368
|
....*....
gi 486168906 451 AVFTIWLPV 459
Cdd:PRK09303 369 SCFHFTLPV 377
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
254-461 |
1.14e-24 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 107.33 E-value: 1.14e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 254 VAHEIRNPLSSIKGLAKYFAErTPAGGESHELAQVMAKEADRLNRVVSELLELVK----PAHLTLQTVNLNDIITHSLNL 329
Cdd:PRK11091 290 ISHELRTPLNGIVGLSRILLD-TELTAEQRKYLKTIHVSAITLGNIFNDIIDMDKmerrKLQLDNQPIDFTDFLADLENL 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 330 VSQDAQSREIQLRFTANETL-KRIQADPDRLTQVLLNLYLNAIHaIGRQGTISVEAKESGTDRVIITVTDSGKGIAPDQL 408
Cdd:PRK11091 369 SGLQAEQKGLRFDLEPLLPLpHKVITDGTRLRQILWNLISNAVK-FTQQGGVTVRVRYEEGDMLTFEVEDSGIGIPEDEL 447
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 409 EAIFTPYFTTK-------ADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPVIA 461
Cdd:PRK11091 448 DKIFAMYYQVKdshggkpATGTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIHAPA 507
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
221-459 |
8.42e-24 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 103.98 E-value: 8.42e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 221 FFWHQRYQRSHRELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYF---AERTPAGGESHELAQVMAKEA-DRL 296
Cdd:PRK13557 137 FFGSQLDVSRRRDAEDALRQAQKMEALGQLTGGIAHDFNNLLQVMSGYLDVIqaaLSHPDADRGRMARSVENIRAAaERA 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 297 NRVVSELLELVKPAHLTLQTVNLNDIITHSLNLVSQdAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGR 376
Cdd:PRK13557 217 ATLTQQLLAFARKQRLEGRVLNLNGLVSGMGELAER-TLGDAVTIETDLAPDLWNCRIDPTQAEVALLNVLINARDAMPE 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 377 QGTISVEAKESGTDR--------------VIITVTDSGKGIAPDQLEAIFTPYFTTKAD--GTGLGLAVVQNIIEQHGGA 440
Cdd:PRK13557 296 GGRVTIRTRNVEIEDedlamyhglppgryVSIAVTDTGSGMPPEILARVMDPFFTTKEEgkGTGLGLSMVYGFAKQSGGA 375
|
250
....*....|....*....
gi 486168906 441 IKVKSIEGKGAVFTIWLPV 459
Cdd:PRK13557 376 VRIYSEVGEGTTVRLYFPA 394
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
359-459 |
1.16e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 95.25 E-value: 1.16e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHaIGRQGTISV----EAKESGTDRVIITVTDSGKGIAPDQLEAIFTPY------FTTKADGTGLGLA 428
Cdd:cd16922 1 LRQILLNLLGNAIK-FTEEGEVTLrvslEEEEEDGVQLRFSVEDTGIGIPEEQQARLFEPFsqadssTTRKYGGTGLGLA 79
|
90 100 110
....*....|....*....|....*....|.
gi 486168906 429 VVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:cd16922 80 ISKKLVELMGGDISVESEPGQGSTFTFTLPL 110
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-458 |
3.28e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 93.93 E-value: 3.28e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHAigRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYF------TTKADGTGLGLAVVQN 432
Cdd:cd16949 1 LARALENVLRNALRY--SPSKILLDISQDG-DQWTITITDDGPGVPEDQLEQIFLPFYrvdsarDRESGGTGLGLAIAER 77
|
90 100
....*....|....*....|....*.
gi 486168906 433 IIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:cd16949 78 AIEQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-457 |
4.70e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 93.29 E-value: 4.70e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHAIGRQ--GTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYFTTK--ADGTGLGLAVVQNII 434
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVenPRIRIAARRLG-GRLVLVVRDNGPGIAEEHLSRVFDPFFTTKpvGKGTGLGLSISYGIV 79
|
90 100
....*....|....*....|...
gi 486168906 435 EQHGGAIKVKSIEGKGAVFTIWL 457
Cdd:cd16976 80 EEHGGRLSVANEEGAGARFTFDL 102
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
224-452 |
6.02e-23 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 102.07 E-value: 6.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 224 HQRYQRSHRELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKglAKYFAERTPAGGESHELAQV----MAKEADRLNRV 299
Cdd:COG4192 410 RKRIEKNLRQTQDELIQAAKMAVVGQTMTSLAHELNQPLNAMS--MYLFSAKKALEQENYAQLPTsldkIEGLIERMDKI 487
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 300 VSELLELVKPAHLTLQTVNLNDIITHSLNLVSQDAQSREIQLRFtanETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGT 379
Cdd:COG4192 488 IKSLRQFSRKSDTPLQPVDLRQVIEQAWELVESRAKPQQITLHI---PDDLMVQGDQVLLEQVLVNLLVNALDAVATQPQ 564
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 486168906 380 ISVEAKESgTDRVIITVTDSGKGIApdQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAV 452
Cdd:COG4192 565 ISVDLLSN-AENLRVAISDNGNGWP--LVDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLYLASTLERGAM 634
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
228-461 |
2.49e-22 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 100.49 E-value: 2.49e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 228 QRSHrELLDAMKRKEKLVAMG--HLAAgVAHEIRNPLSSIKGlAKYFAERTPAGGESHELAQVMAKEADRLNRVVSELLE 305
Cdd:PRK15347 379 ERTQ-ALAEAKQRAEQANKRKseHLTT-ISHEIRTPLNGVLG-ALELLQNTPLTAEQMDLADTARQCTLSLLAIINNLLD 455
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 306 L--VKPAHLTL--QTVNLNDIITHSLNLVSQDAQSREIQLR-FTANETLKRIQADPDRLTQVLLNLYLNAIHaIGRQGTI 380
Cdd:PRK15347 456 FsrIESGQMTLslEETALLPLLDQAMLTIQGPAQSKSLTLRtFVGAHVPLYLHLDSLRLRQILVNLLGNAVK-FTETGGI 534
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 381 SVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYFTT--KADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:PRK15347 535 RLRVKRHE-QQLCFTVEDTGCGIDIQQQQQIFTPFYQAdtHSQGTGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLP 613
|
...
gi 486168906 459 VIA 461
Cdd:PRK15347 614 LNE 616
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
355-458 |
3.03e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 91.06 E-value: 3.03e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 355 DPDRLTQVLLNLYLNAIHAI-GR-----QGTISVEAKESGtdRVIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLA 428
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIeGRpsdvgEVRIRVEADQDG--RIVLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGLA 78
|
90 100 110
....*....|....*....|....*....|
gi 486168906 429 VVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:cd16944 79 IVKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
254-458 |
4.98e-22 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 98.08 E-value: 4.98e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 254 VAHEIRNPLSSIKgLAKYFAERTpaGGESHELAQVmAKEADRLNRVVSELLEL----VKpAHLTLQTVNLNDIITHSLNL 329
Cdd:PRK09470 250 ISHELRTPLTRLQ-LATALLRRR--QGESKELERI-ETEAQRLDSMINDLLVLsrnqQK-NHLERETFKANSLWSEVLED 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 330 VSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGtdrVIITVTDSGKGIAPDQLE 409
Cdd:PRK09470 325 AKFEAEQMGKSLTVSAPPGPWPINGNPNALASALENIVRNALRYSHTKIEVAFSVDKDG---LTITVDDDGPGVPEEERE 401
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 486168906 410 AIFTPYFTT------KADGTGLGLAVVQNIIEQHGGAIKV-KSIEGkGAVFTIWLP 458
Cdd:PRK09470 402 QIFRPFYRVdeardrESGGTGLGLAIVENAIQQHRGWVKAeDSPLG-GLRLTIWLP 456
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
250-459 |
7.03e-22 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 97.67 E-value: 7.03e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 250 LAAGVAHEIRNPLSSIKgLAkyfAERTPAggESHELAQVMAKEADRLNRVVSELLELVKP-AHLTLQTVNLNDIITHSLN 328
Cdd:PRK09467 232 LMAGVSHDLRTPLTRIR-LA---TEMMSE--EDGYLAESINKDIEECNAIIEQFIDYLRTgQEMPMEMADLNALLGEVIA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 329 lvSQDAQSREIQLRFtaNETLKRIQADPDRLTQVLLNLYLNAIhaigRQGTISVEAkESGTD--RVIITVTDSGKGIAPD 406
Cdd:PRK09467 306 --AESGYEREIETAL--QPGPIEVPMNPIAIKRALANLVVNAA----RYGNGWIKV-SSGTEgkRAWFQVEDDGPGIPPE 376
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 486168906 407 QLEAIFTPYftTKAD------GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:PRK09467 377 QLKHLFQPF--TRGDsargssGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLPL 433
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
359-458 |
4.10e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 88.21 E-value: 4.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHAIGRQGTISVEAKE---------------SGtDRVIITVTDSGKGIAPDQLEAIFTPYFTTK--AD 421
Cdd:cd16919 1 LELAILNLAVNARDAMPEGGRLTIETSNqrvdadyalnyrdliPG-NYVCLEVSDTGSGMPAEVLRRAFEPFFTTKevGK 79
|
90 100 110
....*....|....*....|....*....|....*..
gi 486168906 422 GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:cd16919 80 GTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
355-458 |
1.17e-20 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 86.78 E-value: 1.17e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 355 DPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGTDRVIITVTDSGKGIAPDQLEAIFTPY------FTTKADGTGLGLA 428
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRCILEKFRLNRFLLTVSDSGPGIPPNLREEIFERFrqgdgsSTRAHGGTGLGLS 80
|
90 100 110
....*....|....*....|....*....|
gi 486168906 429 VVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:cd16925 81 IVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-458 |
3.60e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 85.53 E-value: 3.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHAI-GRQGTISVEAKesgTDRVI------------ITVTDSGKGIAPDQLEAIFTPYFTTKADGTGL 425
Cdd:cd16918 1 LIQVFLNLVRNAAQALaGSGGEIILRTR---TQRQVtlghprhrlalrVSVIDNGPGIPPDLQDTIFYPMVSGRENGTGL 77
|
90 100 110
....*....|....*....|....*....|...
gi 486168906 426 GLAVVQNIIEQHGGAIKVKSIEGKgAVFTIWLP 458
Cdd:cd16918 78 GLAIAQNIVSQHGGVIECDSQPGH-TVFSVSLP 109
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
252-458 |
5.81e-20 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 92.07 E-value: 5.81e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 252 AGVAHEIRNPLSSIKGLAKYFAERTPAGGESHELAQVMAKEADRLNRVVSELLELVKP----AHLTLQTVNLNDIITHSL 327
Cdd:TIGR01386 246 ADLAHELRTPLTNLLGQTQVALSQPRTGEEYREVLESNLEELERLSRMVSDMLFLARAdngqLALERVRLDLAAELAKVA 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 328 NLVSQDAQSREIQLRFTANETLKriqADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGtDRVIITVTDSGKGIAPDQ 407
Cdd:TIGR01386 326 EYFEPLAEERGVRIRVEGEGLVR---GDPQMFRRAISNLLSNALRHTPDGGTITVRIERRS-DEVRVSVSNPGPGIPPEH 401
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 486168906 408 LEAIFTPYF------TTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKgAVFTIWLP 458
Cdd:TIGR01386 402 LSRLFDRFYrvdparSNSGEGTGLGLAIVRSIMEAHGGRASAESPDGK-TRFILRFP 457
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-458 |
2.77e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 82.72 E-value: 2.77e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 365 NLYLNAIHAIGRQG----TISVEAKESGTDrVIITVTDSGKGIAPDQLEAIFTPYFTTKADGT-GLGLAVVQNIIEQHGG 439
Cdd:cd16915 7 NLIDNALDALAATGapnkQVEVFLRDEGDD-LVIEVRDTGPGIAPELRDKVFERGVSTKGQGErGIGLALVRQSVERLGG 85
|
90
....*....|....*....
gi 486168906 440 AIKVKSIEGKGAVFTIWLP 458
Cdd:cd16915 86 SITVESEPGGGTTFSIRIP 104
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
252-459 |
4.75e-18 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 87.27 E-value: 4.75e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 252 AGVAHEIRNPLSSIKGLAKYFAERtPAGGESHELAQVMAKEADRLNRVVSELLELvKPAHLTLQTVNLND-------IIT 324
Cdd:PRK11466 449 AAMSHEIRTPLYGILGTAQLLADN-PALNAQRDDLRAITDSGESLLTILNDILDY-SAIEAGGKNVSVSDepfeprpLLE 526
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 325 HSLNLVSQDAQSREIQLRFTANETLKR-IQADPDRLTQVLLNLYLNAIHAIGRqGTISVEAKESGTdRVIITVTDSGKGI 403
Cdd:PRK11466 527 STLQLMSGRVKGRPIRLATDIADDLPTaLMGDPRRIRQVITNLLSNALRFTDE-GSIVLRSRTDGE-QWLVEVEDSGCGI 604
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 486168906 404 APDQLEAIFTPY--FTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:PRK11466 605 DPAKLAEIFQPFvqVSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPL 662
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
250-459 |
5.27e-18 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 87.01 E-value: 5.27e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 250 LAAGVAHEIRNPLSSIKGLAKYF-----AERTPAGGESHELAQVMakeadrLN--RVVSELLELVKPA----HLTLQTVN 318
Cdd:PRK10490 667 LLAALSHDLRTPLTVLFGQAEILtldlaSEGSPHARQASEIRQQV------LNttRLVNNLLDMARIQsggfNLRKEWLT 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 319 LNDIITHSLNLVSQDAQSREIQLRFTANETLkrIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGtDRVIITVTD 398
Cdd:PRK10490 741 LEEVVGSALQMLEPGLSGHPINLSLPEPLTL--IHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEG-ERLQLDVWD 817
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 486168906 399 SGKGIAPDQLEAIFTPYftTKAD------GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:PRK10490 818 NGPGIPPGQEQLIFDKF--ARGNkesaipGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLPL 882
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
252-458 |
1.57e-17 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 84.29 E-value: 1.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 252 AGVAHEIRNPLSSIKGLAKYFAERTPAGGESHELAQVMAKEADRLNRVVSELLELVK----PAHLTLQTVNLNDIithsL 327
Cdd:PRK11006 209 ANVSHELRTPLTVLQGYLEMMQDQPLEGALREKALHTMREQTQRMEGLVKQLLTLSKieaaPTIDLNEKVDVPMM----L 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 328 NLVSQDAQS---REIQLRFTANETLKrIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGTDrVIITVTDSGKGIA 404
Cdd:PRK11006 285 RVLEREAQTlsqGKHTITFEVDNSLK-VFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQG-AEFSVEDNGPGIA 362
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 486168906 405 PDQLEAI---FtpYFTTKA-----DGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:PRK11006 363 PEHIPRLterF--YRVDKArsrqtGGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLP 422
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
252-459 |
5.47e-16 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 80.06 E-value: 5.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 252 AGVAHEIRNPLSSIKG----LAKYFAERTPaggesHELAQVMAkEADRLNRVVSEL--LELVKPAHLTLQ--TVNLNDII 323
Cdd:PRK10549 245 ADISHELRTPLAVLRGeleaIQDGVRKFTP-----ESVASLQA-EVGTLTKLVDDLhqLSLSDEGALAYRktPVDLVPLL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 324 THSLNLVSQDAQSREIQLRFTANETLkRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAkESGTDRVIITVTDSGKGI 403
Cdd:PRK10549 319 EVAGGAFRERFASRGLTLQLSLPDSA-TVFGDPDRLMQLFNNLLENSLRYTDSGGSLHISA-EQRDKTLRLTFADSAPGV 396
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 486168906 404 APDQLEAIFTPYFTTKAD------GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:PRK10549 397 SDEQLQKLFERFYRTEGSrnrasgGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPL 458
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
350-457 |
1.39e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 72.44 E-value: 1.39e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 350 KRIQADPDRLTQVLLNLYLNAIHAIGrQGTIsVEAKESGTDRVIITVTDSGKGIAPDQLEAIFTPYF---TTKADGTGLG 426
Cdd:cd16940 5 IQVQGDALLLFLLLRNLVDNAVRYSP-QGSR-VEIKLSADDGAVIRVEDNGPGIDEEELEALFERFYrsdGQNYGGSGLG 82
|
90 100 110
....*....|....*....|....*....|.
gi 486168906 427 LAVVQNIIEQHGGAIKVKSIEGKGAVFTIWL 457
Cdd:cd16940 83 LSIVKRIVELHGGQIFLGNAQGGGLEAWVRL 113
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
357-458 |
3.36e-15 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 73.39 E-value: 3.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 357 DRLTQVLLNLYLNAI-HAI-----------GRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEA-------------- 410
Cdd:cd16916 37 EKLADPLTHLLRNAVdHGIeapeerlaagkPPEGTITLRAEHQG-NQVVIEVSDDGRGIDREKIREkaierglitadeaa 115
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 486168906 411 ----------IFTPYFTTKAD-----GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:cd16916 116 tlsddevlnlIFAPGFSTAEQvtdvsGRGVGMDVVKRSIESLGGTIEVESEPGQGTTFTIRLP 178
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
359-458 |
4.04e-15 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 77.65 E-value: 4.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHAIGRQ--GTISVeAKESGTDRVIITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQ 436
Cdd:PRK11086 434 LITILGNLIENALEAVGGEegGEISV-SLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTKGSNRGVGLYLVKQSVEN 512
|
90 100
....*....|....*....|..
gi 486168906 437 HGGAIKVKSIEGKGAVFTIWLP 458
Cdd:PRK11086 513 LGGSIAVESEPGVGTQFFVQIP 534
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-458 |
4.69e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 70.82 E-value: 4.69e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHAI--GRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYFTTKAD----GTGLGLAVVQN 432
Cdd:cd16921 1 LGQVLTNLLGNAIKFRrpRRPPRIEVGAEDVG-EEWTFYVRDNGIGIDPEYAEKVFGIFQRLHSReeyeGTGVGLAIVRK 79
|
90 100
....*....|....*....|....*.
gi 486168906 433 IIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:cd16921 80 IIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
251-458 |
6.27e-15 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 76.73 E-value: 6.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 251 AAGVAHEIRNPLSSIKGLAKYFAERTPAGGESHELAQVMAKEADRLNRVVSELLELVKP----AHLTLQTVNLNDIITHS 326
Cdd:PRK09835 266 SADIAHEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQAdnnqLIPEKKMLDLADEVGKV 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 327 LNLVSQDAQSREIQLRFTANETlkRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESgTDRVIITVTDSGKGIAPD 406
Cdd:PRK09835 346 FDFFEAWAEERGVELRFVGDPC--QVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEV-DHQVQLVVENPGTPIAPE 422
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 486168906 407 QLEAIFTPYFTT------KADGTGLGLAVVQNIIEQHGGAIKVKSiEGKGAVFTIWLP 458
Cdd:PRK09835 423 HLPRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVVAHKGTVAVTS-DARGTRFVISLP 479
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-458 |
7.60e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 70.17 E-value: 7.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIhaigRQGTISVE-AKESGTDRVIITVTDSGKGIAPDQLEAIFTPYFTTKA----DGTGLGLAVVQNI 433
Cdd:cd16950 1 LKRVLSNLVDNAL----RYGGGWVEvSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNargtSGTGLGLAIVQRI 76
|
90 100
....*....|....*....|....*
gi 486168906 434 IEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:cd16950 77 SDAHGGSLTLANRAGGGLCARIELP 101
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
355-458 |
2.64e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 69.03 E-value: 2.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 355 DPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESgTDRVIITVTDSGKGIAPDQLEAIFTPYFTTK------ADGTGLGLA 428
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQT-PQEVRLDVEDSAPGVSDDQLARLFERFYRVEssrnraSGGSGLGLA 79
|
90 100 110
....*....|....*....|....*....|
gi 486168906 429 VVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:cd16946 80 ICHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
232-464 |
4.45e-14 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 74.77 E-value: 4.45e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 232 RELLDAM-----KRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPAGGESHELAQVMAKEADRLNRVVSELLEL 306
Cdd:PRK09959 692 RDLIHALevernKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDV 771
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 307 VKPA----HLTLQTVNLNDIITHSLNLVSQDAQSREIQLRFTA---NETLKRIqaDPDRLTQVLLNLYLNAIHaIGRQGT 379
Cdd:PRK09959 772 DKIEsgnyQLQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSStfpDHYLVKI--DPQAFKQVLSNLLSNALK-FTTEGA 848
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 380 ISVEAKESGTDR----VIITVTDSGKGIAPDQLEAIFTPYFTTKA----DGTGLGLAVVQNIIEQHGGAIKVKSIEGKGA 451
Cdd:PRK09959 849 VKITTSLGHIDDnhavIKMTIMDSGSGLSQEEQQQLFKRYSQTSAgrqqTGSGLGLMICKELIKNMQGDLSLESHPGIGT 928
|
250
....*....|...
gi 486168906 452 VFTIWLPVIARQQ 464
Cdd:PRK09959 929 TFTITIPVEISQQ 941
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
253-459 |
1.72e-13 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 71.94 E-value: 1.72e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 253 GVAHEIRNPLSSIKglakYFAERTPagGESHELAQVMAKEADRLNRVVSELL---ELVKP-AHLTLQTVNLNDIITHSLN 328
Cdd:PRK10604 218 GIAHELRTPLVRLR----YRLEMSD--NLSAAESQALNRDIGQLEALIEELLtyaRLDRPqNELHLSEPDLPAWLSTHLA 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 329 LVSQDAQSREIQLRFTANETLKRiqADPDRLTQVLLNLYLNAI-HAigrQGTISVEAKESGtDRVIITVTDSGKGIAPDQ 407
Cdd:PRK10604 292 DIQAVTPEKTVRLDTPHQGDYGA--LDMRLMERVLDNLLNNALrYA---HSRVRVSLLLDG-NQACLIVEDDGPGIPPEE 365
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 486168906 408 LEAIFTPYF------TTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:PRK10604 366 RERVFEPFVrldpsrDRATGGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWPV 423
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-458 |
1.86e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 66.44 E-value: 1.86e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIH-AIGRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYFTTKADG------TGLGLAVVQ 431
Cdd:cd16953 1 LGQVLRNLIGNAISfSPPDTGRITVSAMPTG-KMVTISVEDEGPGIPQEKLESIFDRFYTERPANeafgqhSGLGLSISR 79
|
90 100 110
....*....|....*....|....*....|.
gi 486168906 432 NIIEQHGGAIKVKSIE----GKGAVFTIWLP 458
Cdd:cd16953 80 QIIEAHGGISVAENHNqpgqVIGARFTVQLP 110
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
283-459 |
3.07e-13 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 71.75 E-value: 3.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 283 HELAQVMAKEADRLNRVVSELLELVkpahLTLQTVNLnDIITHSLN-LVSQDAQS--REIQLRFTANETL--KRIQadpD 357
Cdd:COG0643 205 DESLRELEEALEQLSRLTRELQDGV----MRLRMVPI-STVFNRFPrMVRDLARElgKEVELVIEGEETEldRTVL---E 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 358 RLTQVLLNLYLNAI-HAI---------G--RQGTISVEAKESGtDRVIITVTDSGKGI---------------APDQLEA 410
Cdd:COG0643 277 RLGDPLVHLVRNAVdHGIetpeerlaaGkpETGTITLSAYHEG-GRVVIEVSDDGRGLdlekirakaiekgliTAEEAAA 355
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 486168906 411 ---------IFTPYFTTKAD-----GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:COG0643 356 lsdeellelIFAPGFSTAEEvtdlsGRGVGMDVVKTNIEALGGTIEIESEPGKGTTFTLRLPL 418
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
340-460 |
4.62e-13 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 70.82 E-value: 4.62e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 340 QLRFtaNETLK-RIQADPDRLTQVLLNLYL-----NAI-HAI---GRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLE 409
Cdd:COG2972 314 KLRF--GDRLEvEIEIDEELLDLLIPKLILqplveNAIeHGIepkEGGGTIRISIRKEG-DRLVITVEDNGVGMPEEKLE 390
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 486168906 410 AIFTPyFTTKADGTGLGLAVVQNIIEQH---GGAIKVKSIEGKGAVFTIWLPVI 460
Cdd:COG2972 391 KLLEE-LSSKGEGRGIGLRNVRERLKLYygeEYGLEIESEPGEGTTVTIRIPLE 443
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
255-438 |
6.79e-13 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 70.45 E-value: 6.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 255 AHEIRNPLSSIKGLAKY--FAERTPAGGEsHELAQvMAKEADRLNRVVSELLELVK---PAHL-TLQTVNLNDIITHSLN 328
Cdd:PRK10337 245 AHELRSPLAALKVQTEVaqLSDDDPQARK-KALLQ-LHAGIDRATRLVDQLLTLSRldsLDNLqDVAEIPLEDLLQSAVM 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 329 LVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTISVEAKESGtdrviITVTDSGKGIAPDQL 408
Cdd:PRK10337 323 DIYHTAQQAGIDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARN-----FTVRDNGPGVTPEAL 397
|
170 180 190
....*....|....*....|....*....|....
gi 486168906 409 EAI----FTPYFTTKAdGTGLGLAVVQNIIEQHG 438
Cdd:PRK10337 398 ARIgerfYRPPGQEAT-GSGLGLSIVRRIAKLHG 430
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-459 |
7.52e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 64.37 E-value: 7.52e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHAIGRqgTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYF------TTKADGTGLGLAVVQN 432
Cdd:cd16939 1 MARALDNLLRNALRYAHR--TVRIALLVSG-GRLTLIVEDDGPGIPAAARERVFEPFVrldpsrDRATGGFGLGLAIVHR 77
|
90 100
....*....|....*....|....*..
gi 486168906 433 IIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:cd16939 78 VALWHGGHVECDDSELGGACFRLTWPR 104
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
244-308 |
3.15e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 61.46 E-value: 3.15e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 486168906 244 LVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERTPAGGESHELAQVMAKEADRLNRVVSELLELVK 308
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
246-308 |
3.79e-12 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 61.43 E-value: 3.79e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 486168906 246 AMGHLAAGVAHEIRNPLSSIKGLAKyFAERTPAGGESHELAQVMAKEADRLNRVVSELLELVK 308
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLE-LLLDTELSEEQREYLETILREAERLLRLINDLLDLSR 62
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
246-308 |
4.55e-12 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 61.07 E-value: 4.55e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 486168906 246 AMGHLAAGVAHEIRNPLSSIKGLAKyFAERTPAGGESHELAQVMAKEADRLNRVVSELLELVK 308
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLE-LLRDEKLDEEQREYLETILRSAERLLRLINDLLDLSR 62
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
251-458 |
1.41e-11 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 65.76 E-value: 1.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 251 AAGVAHEIRNPLSSIKgLAKYFAERTpaggeSHELAQVMAKEADRLNRVVSELLELVKP----AHLTLQTVNL-NDIITH 325
Cdd:PRK10755 141 TADVAHELRTPLAGIR-LHLELLEKQ-----HHIDVAPLIARLDQMMHTVEQLLQLARAgqsfSSGHYQTVKLlEDVILP 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 326 SLNLVSQDAQSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAiHAIGRQG---TISVEAKESGTdrvIITVTDSGKG 402
Cdd:PRK10755 215 SQDELSEMLEQRQQTLLLPESAADITVQGDATLLRLLLRNLVENA-HRYSPEGstiTIKLSQEDGGA---VLAVEDEGPG 290
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 486168906 403 IAPDQLEAIFTPY--FTTKADGTGLGLAVVQNIIEQHGGAIKVKS-IEGKGAVFTIWLP 458
Cdd:PRK10755 291 IDESKCGELSKAFvrMDSRYGGIGLGLSIVSRITQLHHGQFFLQNrQERSGTRAWVWLP 349
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
355-457 |
1.48e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 60.94 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 355 DPDRLTQVLLNLYLNAIHAIGRQGTISVEAkESGTDRVIITVTDSGKGIAPDQLEAIFTPYFT-----TKADGTGLGLAV 429
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQL-EADTEGIELLVFDEGSGIPDYALNRVFERFYSlprphSGQKSTGLGLAF 79
|
90 100
....*....|....*....|....*...
gi 486168906 430 VQNIIEQHGGAIKVKSIEGkGAVFTIWL 457
Cdd:cd16945 80 VQEVAQLHGGRITLRNRPD-GVLAFLTL 106
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
355-458 |
1.63e-11 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 66.80 E-value: 1.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 355 DPDRLTQVLLNLYLNAIHaIGRQGTI--SVEAKESGTDRVII--TVTDSGKGIAPDQLEAIFTPYftTKAD--------G 422
Cdd:PRK11107 405 DPLRLQQIITNLVGNAIK-FTESGNIdiLVELRALSNTKVQLevQIRDTGIGISERQQSQLFQAF--RQADasisrrhgG 481
|
90 100 110
....*....|....*....|....*....|....*.
gi 486168906 423 TGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:PRK11107 482 TGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHLP 517
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-458 |
1.68e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 60.48 E-value: 1.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 359 LTQVLLNLYLNAIHAIGRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYF----TTKADGTGLGLAVVQNII 434
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTRIYITSFLTD-DVVNIMFKNPSSHPLDFKLEKLFERFYrgdnSRNTEGAGLGLSIAKAII 79
|
90 100
....*....|....*....|....
gi 486168906 435 EQHGGAIKVkSIEGKGAVFTIWLP 458
Cdd:cd16923 80 ELHGGSASA-EYDDNHDLFKVRLP 102
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-457 |
1.80e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 61.38 E-value: 1.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 353 QADPDRLTQVLLNLYLNAIH--AIGRQGTISVEAKESgtdRVIITVTDSGKGIAPDQLEAIFTPYFTTKAD------GTG 424
Cdd:cd16947 15 NANTEALQRILKNLISNAIKygSDGKFLGMTLREDEK---HVYIDIWDKGKGISETEKDHVFERLYTLEDSrnsakqGNG 91
|
90 100 110
....*....|....*....|....*....|...
gi 486168906 425 LGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWL 457
Cdd:cd16947 92 LGLTITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
222-458 |
2.61e-10 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 62.68 E-value: 2.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 222 FWHQRYQRSHRE---LLDA---MKRKEKLVAMGHLA-----------AGVAHEIRNPLSSIKG---LAKyfaertpagge 281
Cdd:PRK10841 405 FVHSRYRNENVAicvLVDVsarVKMEESLQEMAQAAeqasqsksmflATVSHELRTPLYGIIGnldLLQ----------- 473
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 282 SHELAQvmakEADRL----NRVVSELLELVkpahltlqtvnlNDIITHS------LNLVSQDAQSREIQLRFTANE---- 347
Cdd:PRK10841 474 TKELPK----GVDRLvtamNNSSSLLLKII------------SDILDFSkieseqLKIEPREFSPREVINHITANYlplv 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 348 -----TL---------KRIQADPDRLTQVLLNLYLNAIHaIGRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFT 413
Cdd:PRK10841 538 vkkrlGLycfiepdvpVALNGDPMRLQQVISNLLSNAIK-FTDTGCIVLHVRVDG-DYLSFRVRDTGVGIPAKEVVRLFD 615
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 486168906 414 PYFTTKA------DGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:PRK10841 616 PFFQVGTgvqrnfQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIP 666
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
369-458 |
3.08e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 57.30 E-value: 3.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 369 NAIHAIGRQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFTPYFTTKAD-----GTGLGLAVVQNIIEQHGGAIKV 443
Cdd:cd16948 16 NALKYSKQGGKIEIYSETNE-QGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGrnfqeSTGMGLYLVKKLCDKLGHKIDV 94
|
90
....*....|....*
gi 486168906 444 KSIEGKGAVFTIWLP 458
Cdd:cd16948 95 ESEVGEGTTFTITFP 109
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
355-456 |
5.93e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 56.32 E-value: 5.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 355 DPDRLTQVLLNLYLNAIHAIGRQGTISVEAKEsgtDRVIIT--VTDSGKGIAPDQLEAIFTPYFTTKADGT-----GLGL 427
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYD---EEEYLYfeIWDNGHGFSEQDLKKALELFYRDDTSRRsgghyGMGL 77
|
90 100
....*....|....*....|....*....
gi 486168906 428 AVVQNIIEQHGGAIKVKSIEGKGAVFTIW 456
Cdd:cd16975 78 YIAKNLVEKHGGSLIIENSQKGGAEVTVK 106
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
327-455 |
5.01e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 54.56 E-value: 5.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 327 LNLVSQDaQSREIQLRFTANEtlkRIQADPDRLTQVLLNLYLNAI-HAIGRqgtISVEAKEsGTDRVIITVTDSGKGIAP 405
Cdd:cd16954 10 LNKVYQR-KGVSISLDISPEL---RFPGERNDLMELLGNLLDNACkWCLEF---VEVTARQ-TDGGLHLIVDDDGPGVPE 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 486168906 406 DQLEAIFTPyfTTKAD----GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTI 455
Cdd:cd16954 82 SQRSKIFQR--GQRLDeqrpGQGLGLAIAKEIVEQYGGELSLSDSPLGGARFEV 133
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
314-464 |
1.06e-08 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 57.22 E-value: 1.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 314 LQTVNLNDIITHSLNLVSQDAQSREIQLRFTANEtlkrIQADPDRLTQV--LLN-LYLNAI-HAI--GRQGTISVEAKES 387
Cdd:COG3920 356 WEGVDLRDYLRELLEPLRDSYGGRGIRIELDGPD----VELPADAAVPLglILNeLVTNALkHAFlsGEGGRIRVSWRRE 431
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 486168906 388 GtDRVIITVTDSGKGIAPDqleaiftpyfTTKADGTGLGLAVVQNIIEQHGGAIKVKSieGKGAVFTIWLPVIARQQ 464
Cdd:COG3920 432 D-GRLRLTVSDNGVGLPED----------VDPPARKGLGLRLIRALVRQLGGTLELDR--PEGTRVRITFPLAELAA 495
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-458 |
2.60e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 51.82 E-value: 2.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 365 NLYLNAIHAIGRQGTISV--EAKESGTDrviITVTDSGKGIAPDQLEAIFTPYF------TTKADGTGLGLAVVQNIIEQ 436
Cdd:cd16952 7 NLVSNAVKYTPPSDTITVrwSQEESGAR---LSVEDTGPGIPPEHIPRLTERFYrvdierCRNTGGTGLGLAIVKHVMSR 83
|
90 100
....*....|....*....|..
gi 486168906 437 HGGAIKVKSIEGKGAVFTIWLP 458
Cdd:cd16952 84 HDARLLIASELGKGSRFTCLFP 105
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
253-459 |
2.79e-07 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 51.54 E-value: 2.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 253 GVAHEirnpLSSIK---GLAKYFAERTPAggESHELAQVMAKEADRLNRVVSELLELVKPAhlTLQTVNLNDIIThslNL 329
Cdd:COG4585 64 GVGQS----LSAIKlqlEAARRLLDADPE--AAREELEEIRELAREALAELRRLVRGLRPP--ALDDLGLAAALE---EL 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 330 VSQDAQSREIQLRFTANETLKRIQADpdrltqVLLNLYL-------NAI-HAIGRQGTISVEAKEsgtDRVIITVTDSGK 401
Cdd:COG4585 133 AERLLRAAGIRVELDVDGDPDRLPPE------VELALYRivqealtNALkHAGATRVTVTLEVDD---GELTLTVRDDGV 203
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 486168906 402 GIAPDQleaiftpyfttkADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPV 459
Cdd:COG4585 204 GFDPEA------------APGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRATLPL 249
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
256-465 |
3.60e-07 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 52.63 E-value: 3.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 256 HEIRNPLSSIKGLAKYFAERTPAGGESHELAQvMAKEADRLNRVVSEL-----LELV--KPAH--LTLQTVnLNDIITHS 326
Cdd:PRK10618 459 DELKQPLQSLAQLAAQLRQTSDEEQQQPELDQ-LAEQSDVLVRLVDNIqllnmLETQdwKPEQelFSLQDL-IDEVLPEV 536
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 327 LNLVSQDAQSREIQLRFTANETlkRIqADPDRLTQVLLNLYLNAI--HAIGRQgTISVEAKESGTDRVIITVTDSGKGIA 404
Cdd:PRK10618 537 LPAIKRKGLQLLIHNHLKAEQL--RI-GDRDALRKILLLLLNYAIttTAYGKI-TLEVDQDESSPDRLTIRILDTGAGVS 612
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 486168906 405 PDQLEAIFTPYFT-TKAD----GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLPVIARQQD 465
Cdd:PRK10618 613 IKELDNLHFPFLNqTQGDrygkASGLTFFLCNQLCRKLGGHLTIKSREGLGTRYSIHLKMLAADPE 678
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
355-465 |
1.57e-05 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 47.13 E-value: 1.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 355 DPDRLTQVLLNLYLNAIHAIGR--QGTISVEAKESGT-DRVIITVTDSGKGIAPDQLEAIFTPYFTTKADGT---GLGLA 428
Cdd:PRK15053 429 DSTEFAAIVGNLLDNAFEASLRsdEGNKIVELFLSDEgDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPgehGIGLY 508
|
90 100 110
....*....|....*....|....*....|....*..
gi 486168906 429 VVQNIIEQHGGAIKVKSIEGKGAVFTIWLPVIARQQD 465
Cdd:PRK15053 509 LIASYVTRCGGVITLEDNDPCGTLFSIFIPKVKPNDS 545
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
390-465 |
2.56e-05 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 46.55 E-value: 2.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 390 DRVIITVTDSGKGIAPDQLEAIFTPyfTTKAD----GTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIwlpVIARQQD 465
Cdd:PRK10815 407 EHLHIVVEDDGPGIPESKRELIFDR--GQRADtlrpGQGLGLSVAREITEQYEGKISAGDSPLGGARMEV---IFGRQHS 481
|
|
| HATPase_SpoIIAB-like |
cd16942 |
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein ... |
338-455 |
2.63e-05 |
|
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of SpoIIAB, an anti sigma-F factor and a serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli where, early in sporulation, the cell divides into two unequal compartments: a larger mother cell and a smaller forespore. Sigma-F transcription factor is activated in the forespore directly after the asymmetric septum forms, and its spatial and temporal activation is required for sporulation. Free sigma-F can associate with the RNA polymerase core and activate transcription of the sigma-F regulon, its regulation may comprise a partner-switching mechanism involving SpoIIAB, SpoIIAA, and sigma-F as follows: SpoIIAB can form alternative complexes with either: i) sigma-F, holding it in an inactive form and preventing its association with RNA polymerase, or ii) unphosphorylated SpoIIAA and a nucleotide, either ATP or ADP. In the presence of ATP, SpoIIAB acts as a kinase to specifically phosphorylate a serine residue of SpoIIAA; this phosphorylated form has low affinity for SpoIIAB and dissociates, making SpoIIAB available to capture sigma-F. SpoIIAA may then be dephosphorylated by a SpoIIE serine phosphatase and be free to attack the SpoIIAB sigma-F complex to induce the release of sigma-F.
Pssm-ID: 340418 [Multi-domain] Cd Length: 135 Bit Score: 43.68 E-value: 2.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 338 EIQLRFTA---NETLKRI-------QADP--DRLTQ---VLLNLYLNA-IHAIGRQG----TISVEAKEsgtDRVIITVT 397
Cdd:cd16942 3 EMHLQFSArseNESFARVtvaafvaQLDPtiDELTEiktVVSEAVTNAiIHGYNNDPngivSISVIIED---GVVHLTVR 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 398 DSGKGIaPDqLEAIFTPYFTTKA--DGTGLGLAVVQNIIEQhggaIKVKSIEGKGAVFTI 455
Cdd:cd16942 80 DEGVGI-PD-IEEARQPLFTTKPelERSGMGFTIMENFMDE----VIVESEVNKGTTVYL 133
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
340-433 |
1.04e-04 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 41.82 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 340 QLRFTANETLKRIQADPDRLTQVLLNLY---LNAI-HAIGRQ--GTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIFT 413
Cdd:COG2172 13 LARRAVRALLRELGLDEDDADDLVLAVSeavTNAVrHAYGGDpdGPVEVELELDP-DGLEIEVRDEGPGFDPEDLPDPYS 91
|
90 100
....*....|....*....|
gi 486168906 414 PyfttkADGTGLGLAVVQNI 433
Cdd:COG2172 92 T-----LAEGGRGLFLIRRL 106
|
|
| HATPase_MutL-MLH-PMS-like |
cd16926 |
Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, ... |
357-419 |
4.37e-04 |
|
Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, human MutL homologs (MLH/ PMS), and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of Escherichia coli MutL, human MLH1 (mutL homolog 1), human PMS1 (PMS1 homolog 1, mismatch repair system component), human MLH3 (mutL homolog 3), and human PMS2 (PMS1 homolog 2, mismatch repair system component). MutL homologs (MLH/PMS) participate in MMR (DNA mismatch repair), and in addition have role(s) in DNA damage signaling and suppression of homologous recombination (recombination between partially homologous parental DNAs). The primary role of MutL in MMR is to mediate protein-protein interactions during mismatch recognition and strand removal; a ternary complex is formed between MutS, MutL, and the mismatched DNA, which activates the MutH endonuclease.
Pssm-ID: 340403 [Multi-domain] Cd Length: 188 Bit Score: 41.27 E-value: 4.37e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 486168906 357 DRLTQVLLNLYLNAIHAigrqG--TISVEAKESGTDRviITVTDSGKGIAPDQLEAIFTPYFTTK 419
Cdd:cd16926 12 ERPASVVKELVENSIDA----GatRIDVEIEEGGLKL--IRVTDNGSGISREDLELAFERHATSK 70
|
|
| HATPase_c_2 |
pfam13581 |
Histidine kinase-like ATPase domain; |
334-433 |
5.28e-04 |
|
Histidine kinase-like ATPase domain;
Pssm-ID: 433327 [Multi-domain] Cd Length: 127 Bit Score: 39.96 E-value: 5.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 334 AQSREIQLRFTANetLKRIQADPDRLTQVLLNLY---LNAI-HA--IGRQGTISVEAkESGTDRVIITVTDSGKGIAPDQ 407
Cdd:pfam13581 6 EQLRAARRVLEAV--LRRAGLPEELLDEVELAVGeacTNAVeHAyrEGPEGPVEVRL-TSDGGGLVVTVADSGPPFDPLT 82
|
90 100
....*....|....*....|....*.
gi 486168906 408 LEAIFTPYFTTKADGTGLGLAVVQNI 433
Cdd:pfam13581 83 LPPPDLEEPDEDRKEGGRGLALIRGL 108
|
|
| HATPase_YpdA-like |
cd16955 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
369-458 |
7.45e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli YpdA, a HK of the two-component system (TCS) YpdA-YpdB which is involved in a nutrient sensing regulatory network with YehU-YehT. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), and some have a GAF sensor domain; some contain a DUF3816 domain; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340431 [Multi-domain] Cd Length: 102 Bit Score: 38.98 E-value: 7.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 369 NAI-HAI---GRQGTISVEAKESGTDRVIITVTDSGKGIAPDQLEAIFTPYFttkaDGTGLGLAVV-QNIIEQHGGAIKV 443
Cdd:cd16955 12 NAIvHGIqekKGKGVVKISVKKQLKNRLHIAVEDNGIGISPKVIERVEQDEM----PGNKIGLLNVhQRLKLGYGEGLHI 87
|
90
....*....|....*
gi 486168906 444 KSIEGKGAVFTIWLP 458
Cdd:cd16955 88 RSRPDPGTLIAFYIP 102
|
|
| PRK10547 |
PRK10547 |
chemotaxis protein CheA; Provisional |
411-458 |
1.55e-03 |
|
chemotaxis protein CheA; Provisional
Pssm-ID: 236712 [Multi-domain] Cd Length: 670 Bit Score: 40.87 E-value: 1.55e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 486168906 411 IFTPYFTT-----KADGTGLGLAVVQNIIEQHGGAIKVKSIEGKGAVFTIWLP 458
Cdd:PRK10547 470 IFAPGFSTaeqvtDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGKGTTIRILLP 522
|
|
| HATPase_YpdA-YehU-LytS-like |
cd16924 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
369-458 |
2.80e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA, YehU, Bacillus subtilis LytS, and some hybrid sensor histidine kinases; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. It also includes the HATPase domains of Escherichia coli YpdA and YehU, HKs of YpdA-YpdB and YehU-YehTCSs, which are involved together in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), some having accessory sensor domain(s) such as Cache, HAMP or GAF; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340401 [Multi-domain] Cd Length: 103 Bit Score: 37.43 E-value: 2.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 369 NAI-HAIG---RQGTISVEAKESGtDRVIITVTDSGKGIAPDQLEAIftpyFTTKADGTGLGLAVV-QNIIEQHGG--AI 441
Cdd:cd16924 12 NAIqHGLSpltDKGVVTISALKED-NHVMIEVEDNGRGIDPKVLNIL----GKKPKEGNGIGLYNVhQRLILLFGEdyGI 86
|
90
....*....|....*..
gi 486168906 442 KVKSIEGKGAVFTIWLP 458
Cdd:cd16924 87 HIASEPDKGTRITFTIP 103
|
|
| HATPase_AgrC-ComD-like |
cd16935 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
319-444 |
3.97e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Staphylococcus aureus AgrC which is an HK of the accessory gene regulator (agr) quorum sensing two-component regulatory system (TCS) AgrC-AgrA. The agr system plays a part in the transition from persistent to virulent phenotype. This family also includes Streptococcus pneumoniae ComD HK of the ComD-ComE TCS, involved in quorum sensing and genetic competence.
Pssm-ID: 340412 [Multi-domain] Cd Length: 134 Bit Score: 37.56 E-value: 3.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486168906 319 LNDIITHSLNLvsqdAQSREIQLRFTANETLKrIQADPDRLTQVLLNLYLNAIHAIGRQGT----ISVEAKESGtDRVII 394
Cdd:cd16935 2 LDSLLSEKLEL----AREKGIEFTIEIDIPIL-LPISPLDLCIIFGNLLDNAIEACAKIDKenrfIHLKIRQKK-GFLII 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 486168906 395 TVTDSGKGiapdQLEAIFTPYFTTKAD-GTGLGLAVVQNIIEQHGGAIKVK 444
Cdd:cd16935 76 SIENSYEG----ELKKKNGLFLSTKKDkNHGIGLKSIREIVKKYNGNLSIE 122
|
|
| |
