|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10764 |
PRK10764 |
potassium-tellurite ethidium and proflavin transporter; Provisional |
1-324 |
7.05e-177 |
|
potassium-tellurite ethidium and proflavin transporter; Provisional
Pssm-ID: 236756 Cd Length: 324 Bit Score: 492.54 E-value: 7.05e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 1 MQSDKVLNLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLS 80
Cdd:PRK10764 1 MQSDKVLPLPAGYFGIVLGLIGLGFAWRYAAQLWPLPAWIGEALVALASIIWALLILAYLYKWIRFPESVLAELRHPVQS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 81 SFVSLFPATTMLVAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALG 160
Cdd:PRK10764 81 SFVSLIPITTMLVAIGLVPYSRPLAVVLFSFGVVGQLAFAAWRTAGLWRGGHPEEATTPGLYLPTVANNFVSAMALGALG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 161 YTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLF 240
Cdd:PRK10764 161 YHDAGLLFLGAGVFSWLSLEPVILQRLRSSGELPTALRPSLGIQLAPAFVGCSAYLSVNGGEGDTLAKMLFGYGLLQLLF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 241 MLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLIRTER 320
Cdd:PRK10764 241 LLRLMPWILSQGFNASFWSFSFGVAALATTGLHLGHGSDNGFFHTLAVPLFIFANFIIALLLLRTLALLMQGKLLVRTER 320
|
....
gi 485833286 321 AVLM 324
Cdd:PRK10764 321 AVLM 324
|
|
| TDT_TehA |
cd09324 |
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; This ... |
10-310 |
6.65e-138 |
|
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; This subfamily includes Tellurite resistance protein TehA that belongs to the C4-dicarboxylate transporter/malic acid transport (TDT) protein family and is a homolog of plant Slow Anion Channel-Associated 1 (SLAC1). The tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.
Pssm-ID: 187764 Cd Length: 301 Bit Score: 392.78 E-value: 6.65e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 10 PAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFPAT 89
Cdd:cd09324 1 PVGYFGIVLGLAALGLAWRYAAQLWPLPAIVGESLLALASVVWLLLIGAYAYKWLKYREEARAELRHPVQCCFISLIPIT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 90 TMLVAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALGYTDAGLVFL 169
Cdd:cd09324 81 TMLVGIALYPYSRLLAEVLIVLGIIGQLAFAAWRTGGLWQGGHFPEATTPVLYLPTVAGNFVSASALAALGYHDLGMLFF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 170 GAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLFMLRLMPWYL 249
Cdd:cd09324 161 GAGMFSWLSLEPVILQRLRTSPPLPPALRPTLGIQLAPAFVGCSAYLSLNGGEVDLLAKMLWGYGLLQLLFLLRLLPWIA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 485833286 250 SQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLM 310
Cdd:cd09324 241 EQGFSMGFWAFSFGLAAMATSGLHLYHGGVLGPLSLLALALFNVANGLIALLTLGTLTLGL 301
|
|
| tdt |
TIGR00816 |
C4-dicarboxylate transporter/malic acid transport protein; The Tellurite-Resistance ... |
9-312 |
4.68e-102 |
|
C4-dicarboxylate transporter/malic acid transport protein; The Tellurite-Resistance/Dicarboxylate Transporter (TDT) Family (TC 2.A.16)Two members of the TDT family have been functionally characterized. One is the TehA protein of E. coli which has been implicated in resistance to tellurite; the other is the Mae1 protein of S. pombe which functions in the uptake of malate and other dicarboxylates by a proton symportmechanism. These proteins exhibit 10 putative transmembrane a-helicalspanners (TMSs). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273285 Cd Length: 320 Bit Score: 302.40 E-value: 4.68e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 9 LPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFPA 88
Cdd:TIGR00816 1 FPWGWFAIVLGTGGLALASLSYSFYLPILKDLSDVLFILAIALFFLFTSCWLARLIRYPSNVLAELKHPVLSSFIPLIPI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 89 TTMLVAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRG-SHPEEATTPGLYLPTVANNFISAMACGALGYTDAGL- 166
Cdd:TIGR00816 81 STMLLGIDFIIWGYPLALGLWYIGAIGQLLFSVIVPFYLFKNeSIEIEHTHPGWYLPPVALIFISAAALAILPYLTHELt 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 167 ----VFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLS-VNGGEGDT-------LAKMLFGYG 234
Cdd:TIGR00816 161 vlfyFGWGAGFFLYLSLEAVLLLRLRLHGLLPSALRPTMFINLAPIGVGIVALINiVNHGEFITikepfliLAIILWGFG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 235 LLQLLFMLRLMPWYLSQ--PFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQG 312
Cdd:TIGR00816 241 LWQLLFAIRLLLWYVKLklPFAMGWWAFIFPLAAYANSTHLVYKGFDFKVFQYIGFGLYVFLNFFWAILLIRTVNKLYVG 320
|
|
| TehA |
COG1275 |
Tellurite resistance protein TehA and related permeases [Defense mechanisms]; |
8-319 |
1.80e-81 |
|
Tellurite resistance protein TehA and related permeases [Defense mechanisms];
Pssm-ID: 440886 Cd Length: 323 Bit Score: 250.15 E-value: 1.80e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 8 NLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFP 87
Cdd:COG1275 11 NLPPAWFALVMGTGGLGLAWRLAAALLPGPAAIAEVLLALAALLFLVLLLLYLLKWLRYPAAVRADLRHPVRGSFFPTIP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 88 ATTMLVAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPE-EATTPGLYLPTVANNFISAMACGALGYTDAGL 166
Cdd:COG1275 91 MALLLLGTGLLPLAPALALVLWLLGVALHLALTVYFPYRLFTGEKFEiEHITPAWFIPVVGNIVVAVAGALLGPLLELSY 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 167 VFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLFMLRLMP 246
Cdd:COG1275 171 AFFGVGLFLYLVLLPLVLYRLIFHKPLPEALRPTLWILLAPPAVGLLAYLALGGGPLDGFALILWGFGLWWLLLLLLLTP 250
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 485833286 247 WYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLIRTE 319
Cdd:COG1275 251 RLLRLPFSPSWWAFTFPLAAYATATLRLAEATGLPFLAVLALALLVLATLVWLYVLVRTLRALARGKLFVPEP 323
|
|
| SLAC1 |
pfam03595 |
Voltage-dependent anion channel; This family of transporters has ten alpha helical ... |
8-297 |
2.64e-33 |
|
Voltage-dependent anion channel; This family of transporters has ten alpha helical transmembrane segments. The structure of a bacterial homolog of SLAC1 shows it to have a trimeric arrangement. The pore is composed of five helices with a conserved Phe residue involved in gating. One homolog, Mae1 from the yeast Schizosaccharomyces pombe, functions as a malate uptake transporter; another, Ssu1 from Saccharomyces cerevisiae and other fungi including Aspergillus fumigatus, is characterized as a sulfite efflux pump; and TehA from Escherichia coli is identified as a tellurite resistance protein by virtue of its association in the tehA/tehB operon. In plants, this family is found in the stomatal guard cells functioning as an anion-transporting pore. Many homologs are incorrectly annotated as tellurite resistance or dicarboxylate transporter (TDT) proteins.
Pssm-ID: 460983 Cd Length: 321 Bit Score: 125.04 E-value: 2.64e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 8 NLPAGYFGIVLGTIGMGFAWRYASqVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFP 87
Cdd:pfam03595 1 HFTPAWFAIVMGTGGLALLLHHLP-YGRGLRTIGLILFILNLVLFLLLLLLYLLRFILYPEAVRAELRHPVESLFLGTFP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 88 ATTMLVAIGFV------PWFRPLAVCLF-SFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMA----C 156
Cdd:pfam03595 80 MGFATIINGLVlvpvpgPWLVTLAWVLWwWIGVALALAFAVGVPFLLFTRHHLLEAMTPAWLLPVVPLMVVAALGallaA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 157 GALGYTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTL---------- 226
Cdd:pfam03595 160 LLLPILVVSYLLWGLGLFLALVILAIYLYRLFTHGLPPAELRPSLFIPLGPPGQGALALLLLGGAAPTILpaltalagei 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 227 --------AKMLFGYGLLQLLFMLRLM---PWYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTN 295
Cdd:pfam03595 240 lyvvalllALFLWGFGLWWFFIAALSVlsaLRRGGLPFNLGWWAFTFPLGAFALATIELGKALDSPFFRVLGTILSVLLV 319
|
..
gi 485833286 296 FI 297
Cdd:pfam03595 320 LV 321
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10764 |
PRK10764 |
potassium-tellurite ethidium and proflavin transporter; Provisional |
1-324 |
7.05e-177 |
|
potassium-tellurite ethidium and proflavin transporter; Provisional
Pssm-ID: 236756 Cd Length: 324 Bit Score: 492.54 E-value: 7.05e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 1 MQSDKVLNLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLS 80
Cdd:PRK10764 1 MQSDKVLPLPAGYFGIVLGLIGLGFAWRYAAQLWPLPAWIGEALVALASIIWALLILAYLYKWIRFPESVLAELRHPVQS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 81 SFVSLFPATTMLVAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALG 160
Cdd:PRK10764 81 SFVSLIPITTMLVAIGLVPYSRPLAVVLFSFGVVGQLAFAAWRTAGLWRGGHPEEATTPGLYLPTVANNFVSAMALGALG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 161 YTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLF 240
Cdd:PRK10764 161 YHDAGLLFLGAGVFSWLSLEPVILQRLRSSGELPTALRPSLGIQLAPAFVGCSAYLSVNGGEGDTLAKMLFGYGLLQLLF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 241 MLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLIRTER 320
Cdd:PRK10764 241 LLRLMPWILSQGFNASFWSFSFGVAALATTGLHLGHGSDNGFFHTLAVPLFIFANFIIALLLLRTLALLMQGKLLVRTER 320
|
....
gi 485833286 321 AVLM 324
Cdd:PRK10764 321 AVLM 324
|
|
| TDT_TehA |
cd09324 |
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; This ... |
10-310 |
6.65e-138 |
|
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; This subfamily includes Tellurite resistance protein TehA that belongs to the C4-dicarboxylate transporter/malic acid transport (TDT) protein family and is a homolog of plant Slow Anion Channel-Associated 1 (SLAC1). The tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.
Pssm-ID: 187764 Cd Length: 301 Bit Score: 392.78 E-value: 6.65e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 10 PAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFPAT 89
Cdd:cd09324 1 PVGYFGIVLGLAALGLAWRYAAQLWPLPAIVGESLLALASVVWLLLIGAYAYKWLKYREEARAELRHPVQCCFISLIPIT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 90 TMLVAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALGYTDAGLVFL 169
Cdd:cd09324 81 TMLVGIALYPYSRLLAEVLIVLGIIGQLAFAAWRTGGLWQGGHFPEATTPVLYLPTVAGNFVSASALAALGYHDLGMLFF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 170 GAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLFMLRLMPWYL 249
Cdd:cd09324 161 GAGMFSWLSLEPVILQRLRTSPPLPPALRPTLGIQLAPAFVGCSAYLSLNGGEVDLLAKMLWGYGLLQLLFLLRLLPWIA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 485833286 250 SQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLM 310
Cdd:cd09324 241 EQGFSMGFWAFSFGLAAMATSGLHLYHGGVLGPLSLLALALFNVANGLIALLTLGTLTLGL 301
|
|
| tdt |
TIGR00816 |
C4-dicarboxylate transporter/malic acid transport protein; The Tellurite-Resistance ... |
9-312 |
4.68e-102 |
|
C4-dicarboxylate transporter/malic acid transport protein; The Tellurite-Resistance/Dicarboxylate Transporter (TDT) Family (TC 2.A.16)Two members of the TDT family have been functionally characterized. One is the TehA protein of E. coli which has been implicated in resistance to tellurite; the other is the Mae1 protein of S. pombe which functions in the uptake of malate and other dicarboxylates by a proton symportmechanism. These proteins exhibit 10 putative transmembrane a-helicalspanners (TMSs). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273285 Cd Length: 320 Bit Score: 302.40 E-value: 4.68e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 9 LPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFPA 88
Cdd:TIGR00816 1 FPWGWFAIVLGTGGLALASLSYSFYLPILKDLSDVLFILAIALFFLFTSCWLARLIRYPSNVLAELKHPVLSSFIPLIPI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 89 TTMLVAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRG-SHPEEATTPGLYLPTVANNFISAMACGALGYTDAGL- 166
Cdd:TIGR00816 81 STMLLGIDFIIWGYPLALGLWYIGAIGQLLFSVIVPFYLFKNeSIEIEHTHPGWYLPPVALIFISAAALAILPYLTHELt 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 167 ----VFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLS-VNGGEGDT-------LAKMLFGYG 234
Cdd:TIGR00816 161 vlfyFGWGAGFFLYLSLEAVLLLRLRLHGLLPSALRPTMFINLAPIGVGIVALINiVNHGEFITikepfliLAIILWGFG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 235 LLQLLFMLRLMPWYLSQ--PFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQG 312
Cdd:TIGR00816 241 LWQLLFAIRLLLWYVKLklPFAMGWWAFIFPLAAYANSTHLVYKGFDFKVFQYIGFGLYVFLNFFWAILLIRTVNKLYVG 320
|
|
| TehA |
COG1275 |
Tellurite resistance protein TehA and related permeases [Defense mechanisms]; |
8-319 |
1.80e-81 |
|
Tellurite resistance protein TehA and related permeases [Defense mechanisms];
Pssm-ID: 440886 Cd Length: 323 Bit Score: 250.15 E-value: 1.80e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 8 NLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFP 87
Cdd:COG1275 11 NLPPAWFALVMGTGGLGLAWRLAAALLPGPAAIAEVLLALAALLFLVLLLLYLLKWLRYPAAVRADLRHPVRGSFFPTIP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 88 ATTMLVAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPE-EATTPGLYLPTVANNFISAMACGALGYTDAGL 166
Cdd:COG1275 91 MALLLLGTGLLPLAPALALVLWLLGVALHLALTVYFPYRLFTGEKFEiEHITPAWFIPVVGNIVVAVAGALLGPLLELSY 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 167 VFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLFMLRLMP 246
Cdd:COG1275 171 AFFGVGLFLYLVLLPLVLYRLIFHKPLPEALRPTLWILLAPPAVGLLAYLALGGGPLDGFALILWGFGLWWLLLLLLLTP 250
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 485833286 247 WYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLIRTE 319
Cdd:COG1275 251 RLLRLPFSPSWWAFTFPLAAYATATLRLAEATGLPFLAVLALALLVLATLVWLYVLVRTLRALARGKLFVPEP 323
|
|
| TDT_TehA_like |
cd09322 |
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA proteins; The ... |
13-302 |
8.52e-76 |
|
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA proteins; The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes members from all three kingdoms, but only three members of the family have been functionally characterized: the TehA protein of E. coli functioning as a tellurite-resistance uptake permease, the Mae1 protein of S. pombe functioning in the uptake of malate and other dicarboxylates, and the sulfite efflux pump (SSU1) of Saccharomyces cerevisiae. In plants, the plasma membrane protein SLAC1 (Slow Anion Channel-Associated 1), which is preferentially expressed in guard cells, encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. SLAC1 is essential in mediating stomatal responses to physiological and stress stimuli. Members of the TDT family exhibit 10 putative transmembrane a-helical spanners (TMSs).
Pssm-ID: 187762 Cd Length: 289 Bit Score: 234.36 E-value: 8.52e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 13 YFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFPATTML 92
Cdd:cd09322 1 LFPIVLGLLGLGLAWLGALLLLGLPSIVGEILGILALLLWLLLLLKYLLKLLRYPEAVKAELRHPVRASFFATFSMSLML 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 93 VAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACgALGYTDAGLVFLGAG 172
Cdd:cd09322 81 LSIYLLPYSPLLARVLWILGAVLHLVFTLYFVSRWIRGGKFLEHVTPSWFIPYVGNIVVPVTGP-ALGGPELGWFFFGVG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 173 VFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLFMLRLMPWYLSQP 252
Cdd:cd09322 160 LIFWLVLLPLVLYRLIFHEPLPEPLRPTLAILLAPPSLGLAAYLALFGGPIDLFALILLGLALFLFLLLLRLLPRLLKLP 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 485833286 253 FNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILL 302
Cdd:cd09322 240 FSPSWWAFTFPLAALAIALLKMAAYLGSGFLQLLALVLLELLTAVILVLY 289
|
|
| TDT_SLAC1_like |
cd09323 |
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes SLAC1 (Slow Anion ... |
8-305 |
1.75e-50 |
|
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes SLAC1 (Slow Anion Channel-Associated 1); SLAC1 (Slow Anion Channel-Associated 1) is a plasma membrane protein, preferentially expressed in guard cells, which encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. It is essential for stomatal closure in response to carbon dioxide, abscisic acid, ozone, light/dark transitions, humidity change, calcium ions, hydrogen peroxide and nitric oxide. In the Arabidopsis genome, SLAC1 is part of a gene family with five members and encodes a membrane protein that has ten putative transmembrane domains flanked by large N- and C-terminal domains. Mutations in SLAC1 impair slow (S-type) anion channel currents that are activated by cytosolic calcium ions and abscisic acid, but do not affect rapid (R-type) anion channel currents or calcium ion channel function.
Pssm-ID: 187763 Cd Length: 297 Bit Score: 169.65 E-value: 1.75e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 8 NLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFP 87
Cdd:cd09323 1 HFPVSLFAIVMGLSGLALAWRKAAELLGLPAAISEALGWLAVAVFVVLAALYALKILRYPEAVKAEFNHPVRINFFPAIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 88 ATTMLVAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEAT-TPGLYLPTVAnNFISAMACGALGYTDAGL 166
Cdd:cd09323 81 ISLLLLSIALLPYSPVLALALWIIGAVLQLALTLYVVSRWISHRQFQIGHaNPAWFIPVVG-NLVVPIAGVPLGYAEVSW 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 167 VFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNgGEGDTLAKMLFGYGLLQLLFMLRLMP 246
Cdd:cd09323 160 FFFSVGLFFWLVLFTIVFNRLIFHEPLPAKLLPTLFILIAPPAVGFLAYLKLT-GSLDAFARILYYIALFLFLLLLFQVR 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 485833286 247 WYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILLIRT 305
Cdd:cd09323 239 RFRKLPFFLSWWAYSFPLAALAIATLRMAELTGSLFLQVLALVLLALLTLVVAVLLVRT 297
|
|
| SLAC1 |
pfam03595 |
Voltage-dependent anion channel; This family of transporters has ten alpha helical ... |
8-297 |
2.64e-33 |
|
Voltage-dependent anion channel; This family of transporters has ten alpha helical transmembrane segments. The structure of a bacterial homolog of SLAC1 shows it to have a trimeric arrangement. The pore is composed of five helices with a conserved Phe residue involved in gating. One homolog, Mae1 from the yeast Schizosaccharomyces pombe, functions as a malate uptake transporter; another, Ssu1 from Saccharomyces cerevisiae and other fungi including Aspergillus fumigatus, is characterized as a sulfite efflux pump; and TehA from Escherichia coli is identified as a tellurite resistance protein by virtue of its association in the tehA/tehB operon. In plants, this family is found in the stomatal guard cells functioning as an anion-transporting pore. Many homologs are incorrectly annotated as tellurite resistance or dicarboxylate transporter (TDT) proteins.
Pssm-ID: 460983 Cd Length: 321 Bit Score: 125.04 E-value: 2.64e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 8 NLPAGYFGIVLGTIGMGFAWRYASqVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFP 87
Cdd:pfam03595 1 HFTPAWFAIVMGTGGLALLLHHLP-YGRGLRTIGLILFILNLVLFLLLLLLYLLRFILYPEAVRAELRHPVESLFLGTFP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 88 ATTMLVAIGFV------PWFRPLAVCLF-SFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMA----C 156
Cdd:pfam03595 80 MGFATIINGLVlvpvpgPWLVTLAWVLWwWIGVALALAFAVGVPFLLFTRHHLLEAMTPAWLLPVVPLMVVAALGallaA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 157 GALGYTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTL---------- 226
Cdd:pfam03595 160 LLLPILVVSYLLWGLGLFLALVILAIYLYRLFTHGLPPAELRPSLFIPLGPPGQGALALLLLGGAAPTILpaltalagei 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 227 --------AKMLFGYGLLQLLFMLRLM---PWYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTN 295
Cdd:pfam03595 240 lyvvalllALFLWGFGLWWFFIAALSVlsaLRRGGLPFNLGWWAFTFPLGAFALATIELGKALDSPFFRVLGTILSVLLV 319
|
..
gi 485833286 296 FI 297
Cdd:pfam03595 320 LV 321
|
|
| TDT |
cd09299 |
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; The Tellurite-resistance ... |
13-305 |
5.43e-16 |
|
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes members from all three kingdoms, but only three members of the family have been functionally characterized: the TehA protein of E. coli functioning as a tellurite-resistance uptake permease, the Mae1 protein of S. pombe functioning in the uptake of malate and other dicarboxylates, and the sulfite efflux pump (SSU1) of Saccharomyces cerevisiae. In plants, the plasma membrane protein SLAC1 (Slow Anion Channel-Associated 1), which is preferentially expressed in guard cells, encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. SLAC1 is essential in mediating stomatal responses to physiological and stress stimuli. Members of the TDT family exhibit 10 putative transmembrane alpha-helical spanners (TMSs).
Pssm-ID: 187756 Cd Length: 326 Bit Score: 77.37 E-value: 5.43e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 13 YFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRH-PVLSSFVSLFPATTM 91
Cdd:cd09299 1 WFGIVMGTGILSLALYLLPYQFPGLRIIGKILFILAIVIFILFFALWLLRLIRYPRHVVRESHHnPVEASFLAAVPISLF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 92 LVAIGFVPWFRP--------LAVCLFSFGVVVQLAYAAWQTAGLWRGSHPE-EATTPGLYLPTVANNFISAMACGALGYT 162
Cdd:cd09299 81 TIIDFLALYGGAntgrlvilIAYVLWWIGLALSLVSAVGVPYLLFTNHVYEiEHISPAWLLPIVPPMTSAALAGALLPYS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 163 DA----------GLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGG----------- 221
Cdd:cd09299 161 PGgaiqlsviflGYLFFGIGFFLFIFIGAIIFSRLVINKLPPGQLAPTLMIVLGPMGQSIFALLLLGKNarlifflyasf 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 222 ---EGDTLAKMLFGYGLLQLLFMLRLMPWYL--SQPFNASFWSFSF--GVSALATTGLHLGSGSDngFFHTLAvplFIFT 294
Cdd:cd09299 241 lqaLAVFASIILWGFGLWWLLLALVSILRTLrkKLPFSLGWWSYVFplGVYTNGTYALYKLMDLP--AFSIFA---TILL 315
|
330
....*....|.
gi 485833286 295 NFIIAILLIRT 305
Cdd:cd09299 316 IILVALWILCT 326
|
|
| TDT_like_3 |
cd09321 |
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; The Tellurite-resistance ... |
12-306 |
6.61e-16 |
|
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes members from all three kingdoms, but only three members of the family have been functionally characterized: the TehA protein of E. coli functioning as a tellurite-resistance uptake permease, the Mae1 protein of S. pombe functioning in the uptake of malate and other dicarboxylates, and the sulfite efflux pump (SSU1) of Saccharomyces cerevisiae. In plants, the plasma membrane protein SLAC1 (Slow Anion Channel-Associated 1), which is preferentially expressed in guard cells, encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. SLAC1 is essential in mediating stomatal responses to physiological and stress stimuli. Members of the TDT family exhibit 10 putative transmembrane a-helical spanners (TMSs).
Pssm-ID: 187761 Cd Length: 327 Bit Score: 76.96 E-value: 6.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 12 GYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFPATTM 91
Cdd:cd09321 4 SWFASVMGTGALAIASYLYSAYFPFLKTLAVFLTYLNFLLFFVLLVPWLLRWILYPKEALADLKHPVLSNFYPTMPIALL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 92 LVA-----IGFVPWFRPLAVCLFSFGVVVQLAYAAWQTAGLWRGSH-PEEATTPGLYLPTVAN-------NFISAMACGA 158
Cdd:cd09321 84 VLAtniliVGQGPLGYSLALTLWILGSILIFIFSFIVSYIMFINEEiPIEHINPAWFIPPVGLiviplagNFLIPHFPGA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 159 LGYTDA--GLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLS-VNGGEGDTL--------- 226
Cdd:cd09321 164 WQESILviNLFGFGIGFFLFLFLLAIILHRLILHEPPPPELAPTFWINLAPIGAGVVALINlVKALPFAGLenlvdlani 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 227 -AKMLFGYGLLQLLFMLRLMPWYLSQ---PFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAILL 302
Cdd:cd09321 244 fALILWGFGLWWLILAVLLTLYYLKRgnlPFSLGWWAFIFPLGAYTIATYLVAKVLNFSFLSGLGIFLYWLLLILWAITL 323
|
....
gi 485833286 303 IRTF 306
Cdd:cd09321 324 FKTL 327
|
|
| TDT_C4-dicarb_trans |
cd09325 |
C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) ... |
8-304 |
3.08e-11 |
|
C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.
Pssm-ID: 187765 Cd Length: 293 Bit Score: 62.95 E-value: 3.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 8 NLPAGYFGIVLGTIGMGFAWRYASqvwqvSHWLGDGLVILAMIIWGLLtgafITRLIRFPHSVLAEVRHPVLSSFVSLFP 87
Cdd:cd09325 1 KIPIPIAGLALGLASLGNLLELSY-----GSILRNICGLIALILLILL----LLKIILFPKTLKEELKNPVIASVFPTFP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 88 ATTMLVAIGFVPWFRPLAVCLFSFGVVVQL---AYAAWQTAGLWRGSHPeeatTPGLYLPTVAnNFISAMACGALGYTDA 164
Cdd:cd09325 72 MALMLLSTYLKPFFPALAQLLWLLAIILHIiliIYFTYKRILKFNLEHV----FPSWFVVYVG-IVVASVTAPAFGQPLL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485833286 165 GLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLFMLRL 244
Cdd:cd09325 147 GQIAFWFGFVAYLILLPLVLYRLVKIKELPDAALPTIAIFAAPASLCLAGYLNSFPEPNPVLVLFLLILSQLLYFFVLLQ 226
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 485833286 245 MPWYLSQPFNASFWSFSF----GVSALATTGLHLGS-GSDNGFFHTLAVPLFIFTNFIIAILLIR 304
Cdd:cd09325 227 LPRLLKLPFYPSFAAFTFplviSATALKKTSTYLASyGLYLPILKYLALFEILIATVIVLYVLIR 291
|
|
| |
