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Conserved domains on  [gi|485768082|ref|WP_001392526|]
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MULTISPECIES: IS1 family transposase, partial [Gammaproteobacteria]

Protein Classification

IS1-like element transposase( domain architecture ID 1750064)

IS1-like element transposase acting on a specific type of insertion sequences (IS), the simplest class of procaryotic transposable elements which are capable of integrating into numerous sites within genomes via a transposition pathway independent of homologous re combination.

Gene Ontology:  GO:0006313

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS1 super family cl41321
IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family ...
 8-52 1.11e-15

IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family elements usually through a translational frameshift mechanism.


The actual alignment was detected with superfamily member NF033558:

Pssm-ID: 468085 [Multi-domain]  Cd Length: 199  Bit Score: 66.53  E-value: 1.11e-15
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 485768082   8 CPSCsATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTYTASQPGT 52
Cdd:NF033558   1 CPRC-QSDNVVKNGKSVRGKQRYRCKDCGRQFQLDYEYRGYSEGT 44
 
Name Accession Description Interval E-value
transpos_IS1 NF033558
IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family ...
 8-52 1.11e-15

IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family elements usually through a translational frameshift mechanism.


Pssm-ID: 468085 [Multi-domain]  Cd Length: 199  Bit Score: 66.53  E-value: 1.11e-15
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 485768082   8 CPSCsATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTYTASQPGT 52
Cdd:NF033558   1 CPRC-QSDNVVKNGKSVRGKQRYRCKDCGRQFQLDYEYRGYSEGT 44
InsA COG3677
Transposase InsA [Mobilome: prophages, transposons];
1-45 3.49e-11

Transposase InsA [Mobilome: prophages, transposons];


Pssm-ID: 442893 [Multi-domain]  Cd Length: 241  Bit Score: 55.26  E-value: 3.49e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 485768082   1 MASVSISCPSCSATDgVVRNGKSTAGHQRYLCSHCRKTWQLQFTY 45
Cdd:COG3677   12 RWPNGPVCPHCGSTR-IVKNGKTRNGRQRYRCKDCGRTFTVTTGT 55
Zn_Tnp_IS1 pfam03811
InsA N-terminal domain; This appears to be a short zinc binding domain found in IS1 InsA ...
 1-36 4.93e-10

InsA N-terminal domain; This appears to be a short zinc binding domain found in IS1 InsA family protein. It is found at the N-terminus of the protein and may be a DNA-binding domain.


Pssm-ID: 281762 [Multi-domain]  Cd Length: 35  Bit Score: 48.36  E-value: 4.93e-10
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 485768082   1 MASVSISCPSCSATDgVVRNGKSTAGHQRYLCSHCR 36
Cdd:pfam03811  1 MASVSIHCPRCSSTD-VYRHGKSTAGHQRFRCRHCR 35
transpos_ISL3 NF033550
ISL3 family transposase;
7-43 1.78e-03

ISL3 family transposase;


Pssm-ID: 468079 [Multi-domain]  Cd Length: 369  Bit Score: 33.71  E-value: 1.78e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 485768082   7 SCPSC-SATDGVVRNGKSTAGH--------------QRYLCSHCRKTWQLQF 43
Cdd:NF033550  12 TCPECgKPSRRVHDTGKRRIRHlpifgrpvylelrvRRFKCPECGKTFTEEL 63
 
Name Accession Description Interval E-value
transpos_IS1 NF033558
IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family ...
 8-52 1.11e-15

IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family elements usually through a translational frameshift mechanism.


Pssm-ID: 468085 [Multi-domain]  Cd Length: 199  Bit Score: 66.53  E-value: 1.11e-15
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 485768082   8 CPSCsATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTYTASQPGT 52
Cdd:NF033558   1 CPRC-QSDNVVKNGKSVRGKQRYRCKDCGRQFQLDYEYRGYSEGT 44
InsA COG3677
Transposase InsA [Mobilome: prophages, transposons];
1-45 3.49e-11

Transposase InsA [Mobilome: prophages, transposons];


Pssm-ID: 442893 [Multi-domain]  Cd Length: 241  Bit Score: 55.26  E-value: 3.49e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 485768082   1 MASVSISCPSCSATDgVVRNGKSTAGHQRYLCSHCRKTWQLQFTY 45
Cdd:COG3677   12 RWPNGPVCPHCGSTR-IVKNGKTRNGRQRYRCKDCGRTFTVTTGT 55
Zn_Tnp_IS1 pfam03811
InsA N-terminal domain; This appears to be a short zinc binding domain found in IS1 InsA ...
 1-36 4.93e-10

InsA N-terminal domain; This appears to be a short zinc binding domain found in IS1 InsA family protein. It is found at the N-terminus of the protein and may be a DNA-binding domain.


Pssm-ID: 281762 [Multi-domain]  Cd Length: 35  Bit Score: 48.36  E-value: 4.93e-10
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 485768082   1 MASVSISCPSCSATDgVVRNGKSTAGHQRYLCSHCR 36
Cdd:pfam03811  1 MASVSIHCPRCSSTD-VYRHGKSTAGHQRFRCRHCR 35
transpos_ISL3 NF033550
ISL3 family transposase;
7-43 1.78e-03

ISL3 family transposase;


Pssm-ID: 468079 [Multi-domain]  Cd Length: 369  Bit Score: 33.71  E-value: 1.78e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 485768082   7 SCPSC-SATDGVVRNGKSTAGH--------------QRYLCSHCRKTWQLQF 43
Cdd:NF033550  12 TCPECgKPSRRVHDTGKRRIRHlpifgrpvylelrvRRFKCPECGKTFTEEL 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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