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Conserved domains on  [gi|447189999|ref|WP_001267255|]
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MULTISPECIES: mechanosensitive channel protein [Enterobacteriaceae]

Protein Classification

mechanosensitive ion channel family protein( domain architecture ID 11485356)

mechanosensitive ion channel family protein functions in osmotic regulation in response to changing environmental and developmental signals; similar to Escherichia coli moderate conductance mechanosensitive channel YbiO

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK11465 PRK11465
putative mechanosensitive channel protein; Provisional
 1-741 0e+00

putative mechanosensitive channel protein; Provisional


:

Pssm-ID: 183147 [Multi-domain]  Cd Length: 741  Bit Score: 1462.30  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999   1 MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQKKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEP 80
Cdd:PRK11465   1 MRWILFILFCLLGAPAHAVSIPGVTTTTSTDSTTEPAPEPDIEQKKAAYAALADVLDNDTSRKELIDQLRTAAATPPAEP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999  81 VPKIVPPTLVEEQTVLQKVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL 160
Cdd:PRK11465  81 VPKIVPPTLVEEKTVLQNVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFLMLAVLVFGFYWLIRLCAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 161 PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAVL 240
Cdd:PRK11465 161 PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQLLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 241 RLIFCPNVAELRPFTIQDESARYWSRRLSWLSSLIGYGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKE 320
Cdd:PRK11465 241 RLIFCPNVPELRPFTIQDASARYWNRRLSWLSSLIGYGLIVAVPIISNQVNVQVGALANVIIMLCMTVWALYLIFRNKKE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 321 ITQHLLNFAEHSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFSRWLAK 400
Cdd:PRK11465 321 ITQHLLNLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFTRWIAK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 401 TITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFDFWNWLQNGAGQKTVDILIRIALILFFSAVG 480
Cdd:PRK11465 401 TITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLNAWGLFDFWNWLQNGAGEKTVDILIRIALILFFSAVG 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 481 WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 560
Cdd:PRK11465 481 WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 561 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 640
Cdd:PRK11465 561 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 640

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 641 KANQALKDAVAELMENEEIRGLVIGEPNFAGIVGLSNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY 720
Cdd:PRK11465 641 KANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY 720

                        730       740
                 ....*....|....*....|.
gi 447189999 721 QVLPAPGAAPAEPLPPGEPTL 741
Cdd:PRK11465 721 QVLPAPGATPAEPLPPGEPTL 741
 
Name Accession Description Interval E-value
PRK11465 PRK11465
putative mechanosensitive channel protein; Provisional
 1-741 0e+00

putative mechanosensitive channel protein; Provisional


Pssm-ID: 183147 [Multi-domain]  Cd Length: 741  Bit Score: 1462.30  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999   1 MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQKKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEP 80
Cdd:PRK11465   1 MRWILFILFCLLGAPAHAVSIPGVTTTTSTDSTTEPAPEPDIEQKKAAYAALADVLDNDTSRKELIDQLRTAAATPPAEP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999  81 VPKIVPPTLVEEQTVLQKVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL 160
Cdd:PRK11465  81 VPKIVPPTLVEEKTVLQNVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFLMLAVLVFGFYWLIRLCAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 161 PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAVL 240
Cdd:PRK11465 161 PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQLLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 241 RLIFCPNVAELRPFTIQDESARYWSRRLSWLSSLIGYGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKE 320
Cdd:PRK11465 241 RLIFCPNVPELRPFTIQDASARYWNRRLSWLSSLIGYGLIVAVPIISNQVNVQVGALANVIIMLCMTVWALYLIFRNKKE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 321 ITQHLLNFAEHSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFSRWLAK 400
Cdd:PRK11465 321 ITQHLLNLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFTRWIAK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 401 TITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFDFWNWLQNGAGQKTVDILIRIALILFFSAVG 480
Cdd:PRK11465 401 TITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLNAWGLFDFWNWLQNGAGEKTVDILIRIALILFFSAVG 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 481 WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 560
Cdd:PRK11465 481 WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 561 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 640
Cdd:PRK11465 561 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 640

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 641 KANQALKDAVAELMENEEIRGLVIGEPNFAGIVGLSNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY 720
Cdd:PRK11465 641 KANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY 720

                        730       740
                 ....*....|....*....|.
gi 447189999 721 QVLPAPGAAPAEPLPPGEPTL 741
Cdd:PRK11465 721 QVLPAPGATPAEPLPPGEPTL 741
MscS COG0668
Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];
440-722 4.68e-43

Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440432 [Multi-domain]  Cd Length: 276  Bit Score: 156.96  E-value: 4.68e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 440 MLLLSAWGLFDFWNWLQNGAGQkTVDILIRIALILFFSAVGWTVLASLIENRLASdihgrplpSARTRTLLTLFRNALAV 519
Cdd:COG0668    1 EALAQLWSLLGLLLLLGELLLA-LLPKLLLALLILLIGWLLIRLLRRLIRRLLRR--------ARRDRTLLPLLRNILKI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 520 IISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGV 599
Cdd:COG0668   72 LIVIIAILLILSILGVNITSLLAGLGAAGLAIGLAAQDLLSNFIAGIFILLERPFRVGDWIEVGGVEGTVEEIGLRSTRL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 600 RQDTGAYHIIPWSSI--TTFANFVRGIGS-VVANYDVDRHEDADKANQALKDAVAELmeneeirGLVIGEPNFAGIVGLS 676
Cdd:COG0668  152 RTLDGRLVTIPNSKIlsSPITNYSRGPTRrVDVTIGVDYDTDIDKARELLKEILEEL-------PRILKDPAVVGVTELG 224

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 447189999 677 NTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQV 722
Cdd:COG0668  225 DSSVNLRVRAWTKPGDYWDVRRDIRERIKAALDEAGIEIPFPTRTV 270
MS_channel pfam00924
Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss: ...
 514-714 1.14e-41

Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss:Q58543 of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.


Pssm-ID: 459999 [Multi-domain]  Cd Length: 203  Bit Score: 150.83  E-value: 1.14e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999  514 RNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMS 593
Cdd:pfam00924   1 KKILKYLIIVVGILIVLSYLGVNVSALLAGLGALGLALGFALQDLVSNLVSGIIILFEKPFKIGDWIEIGDIEGTVEDIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999  594 IRSVGVRQDTGAYHIIPWSSITT--FANFVR-GIGSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLvIGEPNFA 670
Cdd:pfam00924  81 LRTTTIRTFDGRLVTIPNSSILTsnIINYSRsPTRRVELSIGVAYSSDPDKLEKVIEILKEAAYEHPLVLKD-PEPPVVF 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 447189999  671 GIVGLSNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVR 714
Cdd:pfam00924 160 GEFGDSSLNFELRVWVKTLPGEYFNVRSELNLRIKKALEENGIE 203
 
Name Accession Description Interval E-value
PRK11465 PRK11465
putative mechanosensitive channel protein; Provisional
 1-741 0e+00

putative mechanosensitive channel protein; Provisional


Pssm-ID: 183147 [Multi-domain]  Cd Length: 741  Bit Score: 1462.30  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999   1 MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQKKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEP 80
Cdd:PRK11465   1 MRWILFILFCLLGAPAHAVSIPGVTTTTSTDSTTEPAPEPDIEQKKAAYAALADVLDNDTSRKELIDQLRTAAATPPAEP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999  81 VPKIVPPTLVEEQTVLQKVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL 160
Cdd:PRK11465  81 VPKIVPPTLVEEKTVLQNVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFLMLAVLVFGFYWLIRLCAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 161 PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAVL 240
Cdd:PRK11465 161 PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQLLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 241 RLIFCPNVAELRPFTIQDESARYWSRRLSWLSSLIGYGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKE 320
Cdd:PRK11465 241 RLIFCPNVPELRPFTIQDASARYWNRRLSWLSSLIGYGLIVAVPIISNQVNVQVGALANVIIMLCMTVWALYLIFRNKKE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 321 ITQHLLNFAEHSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFSRWLAK 400
Cdd:PRK11465 321 ITQHLLNLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFTRWIAK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 401 TITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFDFWNWLQNGAGQKTVDILIRIALILFFSAVG 480
Cdd:PRK11465 401 TITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLNAWGLFDFWNWLQNGAGEKTVDILIRIALILFFSAVG 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 481 WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 560
Cdd:PRK11465 481 WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK 560

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 561 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 640
Cdd:PRK11465 561 DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD 640

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 641 KANQALKDAVAELMENEEIRGLVIGEPNFAGIVGLSNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY 720
Cdd:PRK11465 641 KANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY 720

                        730       740
                 ....*....|....*....|.
gi 447189999 721 QVLPAPGAAPAEPLPPGEPTL 741
Cdd:PRK11465 721 QVLPAPGATPAEPLPPGEPTL 741
MscS COG0668
Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];
440-722 4.68e-43

Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440432 [Multi-domain]  Cd Length: 276  Bit Score: 156.96  E-value: 4.68e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 440 MLLLSAWGLFDFWNWLQNGAGQkTVDILIRIALILFFSAVGWTVLASLIENRLASdihgrplpSARTRTLLTLFRNALAV 519
Cdd:COG0668    1 EALAQLWSLLGLLLLLGELLLA-LLPKLLLALLILLIGWLLIRLLRRLIRRLLRR--------ARRDRTLLPLLRNILKI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 520 IISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGV 599
Cdd:COG0668   72 LIVIIAILLILSILGVNITSLLAGLGAAGLAIGLAAQDLLSNFIAGIFILLERPFRVGDWIEVGGVEGTVEEIGLRSTRL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 600 RQDTGAYHIIPWSSI--TTFANFVRGIGS-VVANYDVDRHEDADKANQALKDAVAELmeneeirGLVIGEPNFAGIVGLS 676
Cdd:COG0668  152 RTLDGRLVTIPNSKIlsSPITNYSRGPTRrVDVTIGVDYDTDIDKARELLKEILEEL-------PRILKDPAVVGVTELG 224

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 447189999 677 NTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQV 722
Cdd:COG0668  225 DSSVNLRVRAWTKPGDYWDVRRDIRERIKAALDEAGIEIPFPTRTV 270
MS_channel pfam00924
Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss: ...
 514-714 1.14e-41

Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss:Q58543 of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.


Pssm-ID: 459999 [Multi-domain]  Cd Length: 203  Bit Score: 150.83  E-value: 1.14e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999  514 RNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMS 593
Cdd:pfam00924   1 KKILKYLIIVVGILIVLSYLGVNVSALLAGLGALGLALGFALQDLVSNLVSGIIILFEKPFKIGDWIEIGDIEGTVEDIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999  594 IRSVGVRQDTGAYHIIPWSSITT--FANFVR-GIGSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLvIGEPNFA 670
Cdd:pfam00924  81 LRTTTIRTFDGRLVTIPNSSILTsnIINYSRsPTRRVELSIGVAYSSDPDKLEKVIEILKEAAYEHPLVLKD-PEPPVVF 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 447189999  671 GIVGLSNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVR 714
Cdd:pfam00924 160 GEFGDSSLNFELRVWVKTLPGEYFNVRSELNLRIKKALEENGIE 203
MscK COG3264
Small-conductance mechanosensitive channel MscK [Cell wall/membrane/envelope biogenesis];
458-722 2.69e-21

Small-conductance mechanosensitive channel MscK [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442495 [Multi-domain]  Cd Length: 281  Bit Score: 94.50  E-value: 2.69e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 458 GAGQKTVDILIRIALILFFSAVGWTVLASLIENRLASDIHGRPlpsartrTLLTLFRNALAVIISTITIMIVLSEIGVNI 537
Cdd:COG3264   14 GGISISLPNLLLALLILVVTYLLARLLSRLLERRLLRRTRLDP-------GLRYLISKLIRYLIIVLGLLIALSALGIDL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 538 APLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITT- 616
Cdd:COG3264   87 TALAALAGALGVGIGFGLQDIVSNFISGLILLFERPFRVGDWIEIGGTEGTVEEIGLRSTRIRTFDGEEVIIPNSELITn 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447189999 617 -FANFVRG--IGSVVANYDVDRHEDADKANQALKDAVAELmeneeirGLVIGEPN-FAGIVGLSNTAFTLRVSFTTL-PL 691
Cdd:COG3264  167 pVINWSLSdpRRRVEIPVGVAYGSDLEKVRELLLEAAREH-------PRVLKDPApSVLFTEFGDSSVNFELRFWVNdPR 239

                        250       260       270
                 ....*....|....*....|....*....|.
gi 447189999 692 KQWTVRFALDSQVKKHFDLAGVRAPVQTYQV 722
Cdd:COG3264  240 DRLRVRSDLNEAIKKAFREEGIEIPFPQRDV 270
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 553-595 5.30e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 40.42  E-value: 5.30e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 447189999  553 FGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIR 595
Cdd:PRK10929  915 FGLQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTR 957
PRK11281 PRK11281
mechanosensitive channel MscK;
553-596 8.08e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 39.89  E-value: 8.08e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 447189999  553 FGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRS 596
Cdd:PRK11281  918 FGLQEIFANFVSGLIILFERPVRIGDTVTIGTFSGTVSKIRIRA 961
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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