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Conserved domains on  [gi|447182855|ref|WP_001260111|]
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MULTISPECIES: lipase family protein [Bacillus]

Protein Classification

Lip2 family protein( domain architecture ID 11466931)

Lip2 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Lip2 COG3675
Predicted lipase [Lipid transport and metabolism];
15-240 4.94e-82

Predicted lipase [Lipid transport and metabolism];


:

Pssm-ID: 442891 [Multi-domain]  Cd Length: 266  Bit Score: 246.20  E-value: 4.94e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  15 LASCCELTYEqykqngifeipdgfqyvqgfqgKAIQTTEWFGFILESEDTIIVAFRGTQTDPDWIIDSLVNQKPYPYALN 94
Cdd:COG3675    1 MASLCKLAYP----------------------VTQGDPEVFGFILRSDDEVIVAFRGTESLTDWLTNLNAAQVPYPFAKT 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  95 GGNVHNGFLSIYESCRDSIMDMLVSLPAHKKLLATGHSLGGALATLHILDARINTAFAQYGLYTFASPKVGDIAFRNYYK 174
Cdd:COG3675   59 GGKVHRGFYRALQSLRELLEDALRPLSPGKRLYVTGHSLGGALATLAAADLERNYIFPVRGLYTFGQPRVGDRSFAKYYN 138

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447182855 175 LQVASSFRFVNLFDVVPLLPPrninfndHDWEYAHVHHNMTFTKNTKSITNNHSITTYK--TCLTSHF 240
Cdd:COG3675  139 LHVPNSYRIVNNNDIVPLLPP-------VWMGYDHVGKLLWLDSLRKDMLTDHSMDNYIhhTDLSQLL 199
 
Name Accession Description Interval E-value
Lip2 COG3675
Predicted lipase [Lipid transport and metabolism];
15-240 4.94e-82

Predicted lipase [Lipid transport and metabolism];


Pssm-ID: 442891 [Multi-domain]  Cd Length: 266  Bit Score: 246.20  E-value: 4.94e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  15 LASCCELTYEqykqngifeipdgfqyvqgfqgKAIQTTEWFGFILESEDTIIVAFRGTQTDPDWIIDSLVNQKPYPYALN 94
Cdd:COG3675    1 MASLCKLAYP----------------------VTQGDPEVFGFILRSDDEVIVAFRGTESLTDWLTNLNAAQVPYPFAKT 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  95 GGNVHNGFLSIYESCRDSIMDMLVSLPAHKKLLATGHSLGGALATLHILDARINTAFAQYGLYTFASPKVGDIAFRNYYK 174
Cdd:COG3675   59 GGKVHRGFYRALQSLRELLEDALRPLSPGKRLYVTGHSLGGALATLAAADLERNYIFPVRGLYTFGQPRVGDRSFAKYYN 138

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447182855 175 LQVASSFRFVNLFDVVPLLPPrninfndHDWEYAHVHHNMTFTKNTKSITNNHSITTYK--TCLTSHF 240
Cdd:COG3675  139 LHVPNSYRIVNNNDIVPLLPP-------VWMGYDHVGKLLWLDSLRKDMLTDHSMDNYIhhTDLSQLL 199
Lipase_3 cd00519
Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into ...
 8-216 8.82e-49

Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238287 [Multi-domain]  Cd Length: 229  Bit Score: 159.95  E-value: 8.82e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855   8 DKDTAILLASCCELTYE-------QYKQNGIFEIPDGFQYVQGFQGKAIQTTEWFGFILESEDTIIVAFRGTQTDPDWII 80
Cdd:cd00519    1 DYEKLKYYAKLAAAAYCvdanilaKAVVFADIALLNVFSPDKLLKTDKQYDTQGYVAVDHDRKTIVIAFRGTVSLADWLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  81 DSLVNQKPYPYAL-NGGNVHNGFLSIYESCRDSIMDMLVSLPA---HKKLLATGHSLGGALATLHILDARINTAFAQYGL 156
Cdd:cd00519   81 DLDFSPVPLDPPLcSGGKVHSGFYSAYKSLYNQVLPELKSALKqypDYKIIVTGHSLGGALASLLALDLRLRGPGSDVTV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447182855 157 YTFASPKVGDIAFRNYYKLQVASSFRFVNLFDVVPLLPPRNINFNdhdWEYAHV------HHNMTF 216
Cdd:cd00519  161 YTFGQPRVGNAAFAEYLESTKGRVYRVVHGNDIVPRLPPGSLTPP---EGYTHVgtevwiDHLPYF 223
Lipase_3 pfam01764
Lipase (class 3);
66-197 1.51e-35

Lipase (class 3);


Pssm-ID: 396362 [Multi-domain]  Cd Length: 139  Bit Score: 123.14  E-value: 1.51e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855   66 IVAFRGTQTDPDWIIDSLVNQKPY-PYALNGGNVHNGFLSIYESCRDSIMDMLVSL-PAHK--KLLATGHSLGGALATLH 141
Cdd:pfam01764   1 VVAFRGTNSILDWLTDFDFSLTPFkDFFLGGGKVHSGFLSAYTSVREQVLAELKRLlEKYPdySIVVTGHSLGGALASLA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 447182855  142 ILDARINTAFAQY--GLYTFASPKVGDIAFRNYYKLQVAS-SFRFVNLFDVVPLLPPRN 197
Cdd:pfam01764  81 ALDLVENGLRLSSrvTVVTFGQPRVGNLEFAKLHDSQGPKfSYRVVHQRDIVPRLPPIV 139
PLN03037 PLN03037
lipase class 3 family protein; Provisional
 52-210 9.49e-17

lipase class 3 family protein; Provisional


Pssm-ID: 215547  Cd Length: 525  Bit Score: 78.84  E-value: 9.49e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  52 TEWFGFILESEDT---------IIVAFRGTQTDPDWIIDSLVNQKPY----PYALNGGNVHNGFLSIY-----------E 107
Cdd:PLN03037 215 SNWMGFVAVSGDResqrigrrdIVVAWRGTVAPTEWFMDLRTSLEPFdcdgDHGKNVVKVQSGFLSIYkskseltrynkL 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 108 SCRDSIMDMLVSLPAHKK-------LLATGHSLGGALATLHILDARINT-AFAQYGLYTFASPKVGDIAFRNYYKLQVAS 179
Cdd:PLN03037 295 SASEQVMEEVKRLVNFFKdrgeevsLTITGHSLGGALALLNAYEAARSVpALSNISVISFGAPRVGNLAFKEKLNELGVK 374

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 447182855 180 SFRFVNLFDVVPLLPP-------RNINFNDH--DWEYAHV 210
Cdd:PLN03037 375 VLRVVNKQDIVPKLPGiifnkilNKLNPITSrlNWVYRHV 414
 
Name Accession Description Interval E-value
Lip2 COG3675
Predicted lipase [Lipid transport and metabolism];
15-240 4.94e-82

Predicted lipase [Lipid transport and metabolism];


Pssm-ID: 442891 [Multi-domain]  Cd Length: 266  Bit Score: 246.20  E-value: 4.94e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  15 LASCCELTYEqykqngifeipdgfqyvqgfqgKAIQTTEWFGFILESEDTIIVAFRGTQTDPDWIIDSLVNQKPYPYALN 94
Cdd:COG3675    1 MASLCKLAYP----------------------VTQGDPEVFGFILRSDDEVIVAFRGTESLTDWLTNLNAAQVPYPFAKT 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  95 GGNVHNGFLSIYESCRDSIMDMLVSLPAHKKLLATGHSLGGALATLHILDARINTAFAQYGLYTFASPKVGDIAFRNYYK 174
Cdd:COG3675   59 GGKVHRGFYRALQSLRELLEDALRPLSPGKRLYVTGHSLGGALATLAAADLERNYIFPVRGLYTFGQPRVGDRSFAKYYN 138

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447182855 175 LQVASSFRFVNLFDVVPLLPPrninfndHDWEYAHVHHNMTFTKNTKSITNNHSITTYK--TCLTSHF 240
Cdd:COG3675  139 LHVPNSYRIVNNNDIVPLLPP-------VWMGYDHVGKLLWLDSLRKDMLTDHSMDNYIhhTDLSQLL 199
Lipase_3 cd00519
Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into ...
 8-216 8.82e-49

Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238287 [Multi-domain]  Cd Length: 229  Bit Score: 159.95  E-value: 8.82e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855   8 DKDTAILLASCCELTYE-------QYKQNGIFEIPDGFQYVQGFQGKAIQTTEWFGFILESEDTIIVAFRGTQTDPDWII 80
Cdd:cd00519    1 DYEKLKYYAKLAAAAYCvdanilaKAVVFADIALLNVFSPDKLLKTDKQYDTQGYVAVDHDRKTIVIAFRGTVSLADWLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  81 DSLVNQKPYPYAL-NGGNVHNGFLSIYESCRDSIMDMLVSLPA---HKKLLATGHSLGGALATLHILDARINTAFAQYGL 156
Cdd:cd00519   81 DLDFSPVPLDPPLcSGGKVHSGFYSAYKSLYNQVLPELKSALKqypDYKIIVTGHSLGGALASLLALDLRLRGPGSDVTV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447182855 157 YTFASPKVGDIAFRNYYKLQVASSFRFVNLFDVVPLLPPRNINFNdhdWEYAHV------HHNMTF 216
Cdd:cd00519  161 YTFGQPRVGNAAFAEYLESTKGRVYRVVHGNDIVPRLPPGSLTPP---EGYTHVgtevwiDHLPYF 223
Lipase_3 pfam01764
Lipase (class 3);
66-197 1.51e-35

Lipase (class 3);


Pssm-ID: 396362 [Multi-domain]  Cd Length: 139  Bit Score: 123.14  E-value: 1.51e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855   66 IVAFRGTQTDPDWIIDSLVNQKPY-PYALNGGNVHNGFLSIYESCRDSIMDMLVSL-PAHK--KLLATGHSLGGALATLH 141
Cdd:pfam01764   1 VVAFRGTNSILDWLTDFDFSLTPFkDFFLGGGKVHSGFLSAYTSVREQVLAELKRLlEKYPdySIVVTGHSLGGALASLA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 447182855  142 ILDARINTAFAQY--GLYTFASPKVGDIAFRNYYKLQVAS-SFRFVNLFDVVPLLPPRN 197
Cdd:pfam01764  81 ALDLVENGLRLSSrvTVVTFGQPRVGNLEFAKLHDSQGPKfSYRVVHQRDIVPRLPPIV 139
Lipase cd00741
Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and ...
 100-220 5.10e-20

Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238382 [Multi-domain]  Cd Length: 153  Bit Score: 83.32  E-value: 5.10e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 100 NGFLSIYESCRDSIMDMLVSLPA---HKKLLATGHSLGGALATLHILDARINTAFAQYGLYTFASPKVGDIAFRN--YYK 174
Cdd:cd00741    1 KGFYKAARSLANLVLPLLKSALAqypDYKIHVTGHSLGGALAGLAGLDLRGRGLGRLVRVYTFGPPRVGNAAFAEdrLDP 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 447182855 175 LQVASSFRFVNLFDVVPLLPPRNinfndhdWEYAHVHHNMTFTKNT 220
Cdd:cd00741   81 SDALFVDRIVNDNDIVPRLPPGG-------EGYPHGGAEFYINGGK 119
PLN03037 PLN03037
lipase class 3 family protein; Provisional
 52-210 9.49e-17

lipase class 3 family protein; Provisional


Pssm-ID: 215547  Cd Length: 525  Bit Score: 78.84  E-value: 9.49e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  52 TEWFGFILESEDT---------IIVAFRGTQTDPDWIIDSLVNQKPY----PYALNGGNVHNGFLSIY-----------E 107
Cdd:PLN03037 215 SNWMGFVAVSGDResqrigrrdIVVAWRGTVAPTEWFMDLRTSLEPFdcdgDHGKNVVKVQSGFLSIYkskseltrynkL 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 108 SCRDSIMDMLVSLPAHKK-------LLATGHSLGGALATLHILDARINT-AFAQYGLYTFASPKVGDIAFRNYYKLQVAS 179
Cdd:PLN03037 295 SASEQVMEEVKRLVNFFKdrgeevsLTITGHSLGGALALLNAYEAARSVpALSNISVISFGAPRVGNLAFKEKLNELGVK 374

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 447182855 180 SFRFVNLFDVVPLLPP-------RNINFNDH--DWEYAHV 210
Cdd:PLN03037 375 VLRVVNKQDIVPKLPGiifnkilNKLNPITSrlNWVYRHV 414
PLN02802 PLN02802
triacylglycerol lipase
 46-210 9.61e-16

triacylglycerol lipase


Pssm-ID: 215432  Cd Length: 509  Bit Score: 75.58  E-value: 9.61e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  46 GKAIQTTEWFGFILESEDT----------IIVAFRGTQTDPDW---IIDSLVnQKPYPYALNGG----NVHNGFLSIYES 108
Cdd:PLN02802 224 GWMTQRSSWVGYVAVCDSPreirrmgrrdIVIALRGTATCLEWaenLRAGLV-PMPGDDDDAGDqeqpKVECGFLSLYKT 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 109 CRD---SIMDMLVSlpAHKKLL-----------ATGHSLGGALATLhILD--ARINTAFAQYGLYTFASPKVGDIAFRNY 172
Cdd:PLN02802 303 AGAhvpSLSESVVG--EVRRLMekykgeelsitVTGHSLGAALALL-VADelATCVPAAPPVAVFSFGGPRVGNRAFADR 379

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 447182855 173 YKLQVASSFRFVNLFDVVPLLPPRNINFNDHDWEYAHV 210
Cdd:PLN02802 380 LNARGVKVLRVVNAQDVVTRVPGIAPREELHKWAYAHV 417
PLN02408 PLN02408
phospholipase A1
 54-202 2.23e-14

phospholipase A1


Pssm-ID: 215228  Cd Length: 365  Bit Score: 71.41  E-value: 2.23e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  54 WFGFILESEDT----------IIVAFRGTQTDPDWI------IDSLVNqKPYPYALNGGN----VHNGFLSIYES---CR 110
Cdd:PLN02408  99 WIGYVAVCQDKeeiarlgrrdVVIAFRGTATCLEWLenlratLTRLPN-APTDMNGSGDGsgpmVESGFLSLYTSgtaMG 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 111 DSIMDML---VSLPAHK------KLLATGHSLGGALATLHILDarINTAFAQYGLYT---FASPKVGDIAFRNYYKLQVA 178
Cdd:PLN02408 178 PSLQEMVreeIARLLQSygdeplSLTITGHSLGAALATLTAYD--IKTTFKRAPMVTvisFGGPRVGNRSFRRQLEKQGT 255

                        170       180
                 ....*....|....*....|....
gi 447182855 179 SSFRFVNLFDVVPLLPPRNINFND 202
Cdd:PLN02408 256 KVLRIVNSDDVITKVPGFVIDGEN 279
PLN02310 PLN02310
triacylglycerol lipase
 36-194 1.62e-13

triacylglycerol lipase


Pssm-ID: 215176  Cd Length: 405  Bit Score: 68.86  E-value: 1.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  36 DGFQYVQGFQGKAIQTTEWFGFILESEDT---------IIVAFRGTQTDPDWIIDSLVNQKpypyALNGGNV--HNGFLS 104
Cdd:PLN02310  96 DVPHWLKRSQATWSKDSNWMGYVAVSRDEesqrigrrdIMVAWRGTVAPSEWFLDLETKLE----HIDNTNVkvQEGFLK 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 105 IY----ESCR-------DSIMDMLVSLPAHKK-------LLATGHSLGGALATLHILDARINTAFAQYGLYTFASPKVGD 166
Cdd:PLN02310 172 IYkskdESTRynklsasEQVMQEVKRLVNFYRgkgeevsLTVTGHSLGGALALLNAYEAATTIPDLFVSVISFGAPRVGN 251

                        170       180
                 ....*....|....*....|....*...
gi 447182855 167 IAFRNYYKLQVASSFRFVNLFDVVPLLP 194
Cdd:PLN02310 252 IAFKEKLNELGVKTLRVVVKQDKVPKLP 279
PLN00413 PLN00413
triacylglycerol lipase
 30-209 1.34e-12

triacylglycerol lipase


Pssm-ID: 165792  Cd Length: 479  Bit Score: 66.58  E-value: 1.34e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  30 GIFEIPDGFQYVQGFQGKAIQTTEwfgfilESEDTIIVAFRGTqtDP----DWIIDSLVNqkpYPYALNGGNVHNGFLSI 105
Cdd:PLN00413 173 GFYSCPNDFDKQRSTEVIVIKDTK------DDPNLIIVSFRGT--DPfdadDWCTDLDLS---WHEVKNVGKIHGGFMKA 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 106 -------------------------YESCRDSIMDMLVSLPAHKKLLaTGHSLGGALATLH----ILDARINTAFAQYGL 156
Cdd:PLN00413 242 lglpkegwpeeinldetqnatsllaYYTILRHLKEIFDQNPTSKFIL-SGHSLGGALAILFtavlIMHDEEEMLERLEGV 320

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 447182855 157 YTFASPKVGDIAFRNYYKLQVaSSF-----RFVNLFDVVPLLPprninFNDHDWEYAH 209
Cdd:PLN00413 321 YTFGQPRVGDEDFGIFMKDKL-KEFdvkyeRYVYCNDMVPRLP-----FDDKTLMFKH 372
PLN02753 PLN02753
triacylglycerol lipase
 50-229 1.76e-12

triacylglycerol lipase


Pssm-ID: 178354  Cd Length: 531  Bit Score: 66.28  E-value: 1.76e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  50 QTTEWFGFILESEDT----------IIVAFRGTQTDPDWIIDslvnQKPYPYALNGGN---------VHNGFLSIYE--- 107
Cdd:PLN02753 204 KNANWMGYVAVSDDEtsrnrlgrrdIAIAWRGTVTKLEWIAD----LKDYLKPVSENKircpdpavkVESGFLDLYTdkd 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 108 --------SCRDSIMDMLVSL--------PAHKKLLATGHSLGGALATLHILD-ARINTAFAQYG------LYTFASPKV 164
Cdd:PLN02753 280 ttckfakfSAREQILTEVKRLveehgdddDSDLSITVTGHSLGGALAILSAYDiAEMGLNRSKKGkvipvtVLTYGGPRV 359

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 165 GDIAFRNYYKLQVASSFRFVNLFDVVPLLPPRNINFNDHD----------WEYAHV-------HHNMTFTKNTKSITNNH 227
Cdd:PLN02753 360 GNVRFKDRMEELGVKVLRVVNVHDVVPKSPGLFLNESRPHalmkiaeglpWCYSHVgeelaldHQNSPFLKPSVDLSTAH 439


                 ..
gi 447182855 228 SI 229
Cdd:PLN02753 440 NL 441
PLN02571 PLN02571
triacylglycerol lipase
 52-195 2.94e-12

triacylglycerol lipase


Pssm-ID: 215309  Cd Length: 413  Bit Score: 65.29  E-value: 2.94e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  52 TEWFGFILESEDT---------IIVAFRGTQTDPDWIID---SLVN-QKPYPYALNGGNVHNGFLSIYES---------- 108
Cdd:PLN02571 125 SNWMGYVAVATDEgkallgrrdIVIAWRGTVQTLEWVNDfefNLVSaSKIFGESNDQPKVHQGWYSIYTSdderspfnkt 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 109 -CRDSIMDMLVSLPAHKK-----LLATGHSLGGALATLHILDARIN---------------TAFaqyglyTFASPKVGDI 167
Cdd:PLN02571 205 sARDQVLNEVGRLVEKYKdeeisITICGHSLGAALATLNAVDIVANgfnrsksrpnkscpvTAF------VFASPRVGDS 278

                        170       180
                 ....*....|....*....|....*....
gi 447182855 168 AFRNYYK-LQVASSFRFVNLFDVVPLLPP 195
Cdd:PLN02571 279 DFKKLFSgLKDLRVLRVRNLPDVIPNYPL 307
PLN02761 PLN02761
lipase class 3 family protein
 50-229 1.26e-09

lipase class 3 family protein


Pssm-ID: 215406 [Multi-domain]  Cd Length: 527  Bit Score: 57.75  E-value: 1.26e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  50 QTTEWFGFILESEDT----------IIVAFRGTQTDPDWIIDslvnQKPYPYALNGGN-----VHNGFLSIYESCRDSIM 114
Cdd:PLN02761 189 QHANWMGYVAVATDEeevkrlgrrdIVIAWRGTVTYLEWIYD----LKDILCSANFGDdpsikIELGFHDLYTKKEDSCK 264

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 115 dmLVSLPAHKKLLA----------------------TGHSLGGALATLHILD-ARINTAFA-------QYGLYTFASPKV 164
Cdd:PLN02761 265 --FSSFSAREQVLAevkrlveyygteeegheisitvTGHSLGASLALVSAYDiAELNLNHVpennykiPITVFSFSGPRV 342

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 165 GDIAFRNYYKLQVASSFRFVNLFDVVPLLPP--RNINFN---------DHDWEYAHV-------HHNMTFTKNTKSITNN 226
Cdd:PLN02761 343 GNLRFKERCDELGVKVLRVVNVHDKVPSVPGifTNEKFQfqkyveektSFPWSYAHVgvelaldHKKSPFLKPTKDLGCA 422


                 ...
gi 447182855 227 HSI 229
Cdd:PLN02761 423 HNL 425
PLN02324 PLN02324
triacylglycerol lipase
 52-232 3.92e-09

triacylglycerol lipase


Pssm-ID: 177958  Cd Length: 415  Bit Score: 56.18  E-value: 3.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  52 TEWFGFILESEDT---------IIVAFRGT------QTDPDWIIDSLVNQKPYPYALNGGNVHNGFLSIYE--------- 107
Cdd:PLN02324 112 TNWMGYIAVATDQgkamlgrrdIVVAWRGTlqpyewANDFDFPLESAISVFPVTDPKDNPRIGSGWLDIYTasdsrspyd 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 108 --SCRDSIMDMLVSLPAHKK-----LLATGHSLGGALATLHILD------ARINTAFAQYGL----YTFASPKVGDIAFR 170
Cdd:PLN02324 192 ttSAQEQVQGELKRLLELYKneeisITFTGHSLGAVMSVLSAADlvygkkNKINISLQKKQVpitvFAFGSPRIGDHNFK 271

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 447182855 171 NYYK-LQVASSFRFVNLFDVVPLLPPrnINFNDHDWEYAHVHHNMTFTKNTKSITNNHSITTY 232
Cdd:PLN02324 272 NLVDsLQPLNILRIVNVPDVAPHYPL--LLYTEIGEVLEINTLNSTYLKRSLNFRNYHNLEAY 332
CVT17 COG5153
Putative lipase ATG15 (essential for vacuolar disintegration of autophagic bodies) ...
 15-191 1.55e-08

Putative lipase ATG15 (essential for vacuolar disintegration of autophagic bodies) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444061  Cd Length: 405  Bit Score: 54.25  E-value: 1.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  15 LASCCELTYEQYKQNGIFEIPDGFQYvqgfqgKAIQTTEWFGFILESE---DTIIvAFRGTQTDPDWIIDslVNQKPYPY 91
Cdd:COG5153    1 MQSISEIVYEKLADAATALDIDPFRA------ANDDIDGHFAVALDEKaiyDTII-AFRGTQGKPDWKTD--INASLHDY 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  92 ALNG--------GNVHNGFLSIYESCRDSIMDMLVSL--PAHK-----KLLATGHSLGGALATLHILDARINTAfaqygl 156
Cdd:COG5153   72 DEKNkeadeklpLQVHEGFEQYAAQVMDLDYDGAEELaaEVKKqypdaELSLTGHSLGGALASLVAVATGLSKV------ 145

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 447182855 157 yTFASPKVGDIAFRNYYKLQVASSfRFVNLFDVVP 191
Cdd:COG5153  146 -TFAAPGSGNHALADDLGKRIDAG-EFVKSLDAVA 178
PLN02719 PLN02719
triacylglycerol lipase
 50-229 4.14e-08

triacylglycerol lipase


Pssm-ID: 178321  Cd Length: 518  Bit Score: 53.17  E-value: 4.14e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  50 QTTEWFGFILESEDT-----------IIVAFRGTQTDPDWIIDslVNQKPYPYALNGG-------NVHNGFLSIYE---- 107
Cdd:PLN02719 189 KNANWIGYVAVSDDDeatrcrlgrrdIAIAWRGTVTRLEWIAD--LKDFLKPVSGNGFrcpdpavKAESGFLDLYTdkdt 266

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 108 -------SCRDSIMDMLVSLPAHK--------KLLATGHSLGGALATLHILDArintafAQYGL-------------YTF 159
Cdd:PLN02719 267 ccnfskfSAREQVLTEVKRLVERYgdeegeelSITVTGHSLGGALAVLSAYDV------AEMGLnrtrkgkvipvtaFTY 340

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 160 ASPKVGDIAFRNYYKLQVASSFRFVNLFDVVPLLPPRNINFNDHD----------WEYAHV-------HHNMTFTKNTKS 222
Cdd:PLN02719 341 GGPRVGNIRFKERIEELGVKVLRVVNEHDVVAKSPGLFLNERAPQalmklagglpWCYSHVgemlpldHQKSPFLKPTVD 420


                 ....*..
gi 447182855 223 ITNNHSI 229
Cdd:PLN02719 421 LSTAHNL 427
PLN02934 PLN02934
triacylglycerol lipase
 65-209 1.08e-07

triacylglycerol lipase


Pssm-ID: 215504  Cd Length: 515  Bit Score: 52.09  E-value: 1.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  65 IIVAFRGTQ--TDPDWIIDslvnqkpYPYAL----NGGNVHNGFL----------------------------------- 103
Cdd:PLN02934 223 IVISFRGTEpfDADDWGTD-------FDYSWyeipKVGKVHMGFLeamglgnrddtttfqtslqtkatselkeeeskknl 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 104 ------SIYESCRdSIMDMLVSLPAHKKLLATGHSLGGALATLH--ILDARINTAFAQ--YGLYTFASPKVGDIAF---- 169
Cdd:PLN02934 296 lemverSAYYAVR-SKLKSLLKEHKNAKFVVTGHSLGGALAILFptVLVLQEETEVMKrlLGVYTFGQPRIGNRQLgkfm 374

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 447182855 170 RNYYKLQVASSFRFVNLFDVVPLLPprninFNDHDWEYAH 209
Cdd:PLN02934 375 EAQLNYPVPRYFRVVYCNDLVPRLP-----YDDKTFLYKH 409
PLN02454 PLN02454
triacylglycerol lipase
 52-196 1.39e-06

triacylglycerol lipase


Pssm-ID: 215249  Cd Length: 414  Bit Score: 48.30  E-value: 1.39e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  52 TEWFGFILESEDT---------IIVAFRGTQTDPDWII---DSLVNQKP-YPYALNGGN-----------------VHNG 101
Cdd:PLN02454 110 SNWIGYIAVTSDErtkalgrreIYVAWRGTTRNYEWVDvlgAKLTSADPlLPGPEQDGVvsgsssdsddddekgpkVMLG 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 102 FLSIYE-----------SCRDSIMDMLVSLPAHKK-----LLATGHSLGGALATLHILDARIN---------TAFaqygl 156
Cdd:PLN02454 190 WLTIYTsddprspftklSARSQLLAKIKELLERYKdeklsIVLTGHSLGASLATLAAFDIVENgvsgadipvTAI----- 264

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 447182855 157 yTFASPKVGDIAFRNYYKLQvaSSFRFV---NLFDVVPLLPPR 196
Cdd:PLN02454 265 -VFGSPQVGNKEFNDRFKEH--PNLKILhvrNTIDLIPHYPGG 304
PLN02162 PLN02162
triacylglycerol lipase
 38-194 1.42e-06

triacylglycerol lipase


Pssm-ID: 177821  Cd Length: 475  Bit Score: 48.50  E-value: 1.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855  38 FQYVQGFQGKAIQTTEWFGFILESEDTIIVAFRGTQ--TDPDWIIDSLVNQkpypYAL-NGGNVHNGF------------ 102
Cdd:PLN02162 173 YDFYNAFQESKLTQAFVFKTSSTNPDLIVVSFRGTEpfEAADWCTDLDLSW----YELkNVGKVHAGFsralglqkdggw 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447182855 103 ----LSI-----YESCRDSIMDMLVSLPAHKKLLaTGHSLGGALATL-------HILDARINTAfaqYGLYTFASPKVGD 166
Cdd:PLN02162 249 pkenISLlhqyaYYTIRQMLRDKLARNKNLKYIL-TGHSLGGALAALfpailaiHGEDELLDKL---EGIYTFGQPRVGD 324

                        170       180       190
                 ....*....|....*....|....*....|..
gi 447182855 167 IAFRNYY----KLQVASSFRFVNLFDVVPLLP 194
Cdd:PLN02162 325 EDFGEFMkgvvKKHGIEYERFVYNNDVVPRVP 356
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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