|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10820 |
PRK10820 |
transcriptional regulator TyrR; |
1-513 |
0e+00 |
|
transcriptional regulator TyrR;
Pssm-ID: 236769 [Multi-domain] Cd Length: 520 Bit Score: 1098.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 1 MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTDFSSLMAEIRRISGVTDVRTVPWMPSEREHL 80
Cdd:PRK10820 1 MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFESFSSLMAEIRRIAGVTDVRTVPFMPSEREHR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 81 ALSALLEALPEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNPQSSHNEHVVINGQNFLME 160
Cdd:PRK10820 81 ALSALLEALPEPVLSIDMKGKVELANPASCQLFGQSEEKLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQDFLME 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 161 ITPVHLQNENDEYVLTGAVVMLRSTIRMGQQLQNLSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGK 240
Cdd:PRK10820 161 ITPVYLQDENDQHVLVGAVVMLRSTARMGRQLQNLAVNDDSAFSQIVAVSPKMRQVVEQARKLAMLDAPLLITGDTGTGK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 241 DLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAP-------EGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLR 313
Cdd:PRK10820 241 DLLAYACHLRSPRGKKPFLALNCASIPDDVVESELFGHAPgaypnalEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 314 FLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQG 393
Cdd:PRK10820 321 FLNDGTFRRVGEDHEVHVDVRVICATQKNLVELVQKGEFREDLYYRLNVLTLNLPPLRDRPQDIMPLTELFVARFADEQG 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 394 VPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAAtVAVGEDAMEGSLDDITSRFERSVL 473
Cdd:PRK10820 401 VPRPKLAADLNTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAA-VAVGEDAMEGSLDEITSRFERSVL 479
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 447158237 474 TQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQKKGEE 513
Cdd:PRK10820 480 TRLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQKKGEE 519
|
|
| TyrR |
COG3283 |
Transcriptional regulator TyrR of aromatic amino acids metabolism [Transcription, Amino acid ... |
1-508 |
0e+00 |
|
Transcriptional regulator TyrR of aromatic amino acids metabolism [Transcription, Amino acid transport and metabolism];
Pssm-ID: 442513 [Multi-domain] Cd Length: 514 Bit Score: 946.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 1 MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTDFSSLMAEIRRISGVTDVRTVPWMPSEREHL 80
Cdd:COG3283 1 MRLEVTCEDRLGITRELLDLLVERNIDLRGIEIDPSGRIYLNFPELDFEQFQHLMPEIRRIPGVTDVRTVPFMPSEREHL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 81 ALSALLEALPEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNPQSSHNEHVVINGQNFLME 160
Cdd:COG3283 81 ELDALLEALPDPVFSIDLKGKIELANPAALSLLGLSEEELIGQPLSELLKGFNFSRWLESNEPRPQSERVVINGQDYLAD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 161 ITPVHLQNENDEYVLTGAVVMLRSTIRMGQQLQNLSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGK 240
Cdd:COG3283 161 ILPIYLPDEEGKSILAGAVVTLKSAARLGEQLQALQVNDDSGFDHIVASSPKMRQVIRQAKKMAMLDAPLLIQGETGTGK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 241 DLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAP-------EGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLR 313
Cdd:COG3283 241 ELLARACHLASPRGDKPFLALNCAALPDDVAESELFGYAPgafgnarEGKKGLFEQANGGTVFLDEIGEMSPQLQAKLLR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 314 FLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQG 393
Cdd:COG3283 321 FLQDGTFRRVGEEQEVKVDVRVICATQKDLAELVQEGEFREDLYYRLNVLTLTLPPLRERKSDILPLAEHFVARFSQQLG 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 394 VPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAAtVAVGEDAMEGSLDDITSRFERSVL 473
Cdd:COG3283 401 RPRPRLSPDLVDFLQSYPWPGNVRQLENALYRAVSLLEGDELTPEDLQLPEYAAS-AGLLDDLLEGSLDEIVKRFERSLL 479
|
490 500 510
....*....|....*....|....*....|....*
gi 447158237 474 TQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQ 508
Cdd:COG3283 480 RRLYPSYPSTRKLAKRLGVSHTAIANKLREYGIGK 514
|
|
| Sigma54_activat |
pfam00158 |
Sigma-54 interaction domain; |
206-365 |
4.05e-88 |
|
Sigma-54 interaction domain;
Pssm-ID: 425491 [Multi-domain] Cd Length: 168 Bit Score: 267.73 E-value: 4.05e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 206 IIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGH------- 278
Cdd:pfam00158 1 IIGESPAMQEVLEQAKRVAPTDAPVLITGESGTGKELFARAIHQLSPRADGPFVAVNCAAIPEELLESELFGHekgaftg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 279 APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYY 358
Cdd:pfam00158 81 ADSDRKGLFELADGGTLFLDEIGELPLELQAKLLRVLQEGEFERVGGTKPIKVDVRIIAATNRDLEEAVAEGRFREDLYY 160
|
....*..
gi 447158237 359 RLNVLTL 365
Cdd:pfam00158 161 RLNVIPI 167
|
|
| TF_PrdR |
NF041552 |
sigma-54 dependent transcriptional regulator PrdR; |
203-423 |
8.17e-85 |
|
sigma-54 dependent transcriptional regulator PrdR;
Pssm-ID: 469437 [Multi-domain] Cd Length: 577 Bit Score: 272.92 E-value: 8.17e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 203 FSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAkPYLALNCASIPEDAVESELFGHAP-- 280
Cdd:NF041552 266 FGKIIGKSKKIIKKIEIAKQVAKTNSSVLITGESGTGKEVFARAIHQASGRKG-PFVPVNCSAIPEELFESEFFGYEEga 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 281 ------EGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFRE 354
Cdd:NF041552 345 ftgalkKGKIGKFELANNGTLFLDEIGDMPLSMQAKLLRVLQEKQVRRVGGEKYIKINVRIISATNKDLKKMVKEGKFRE 424
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447158237 355 DLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNAI 423
Cdd:NF041552 425 DLYYRLNVVEIELPPLRERKEDIPLLINYFLKEICKENNKEIPKIDKEVYDILQNYKWKGNIRELKNTI 493
|
|
| nifA |
TIGR01817 |
Nif-specific regulatory protein; This model represents NifA, a DNA-binding regulatory protein ... |
206-442 |
7.62e-83 |
|
Nif-specific regulatory protein; This model represents NifA, a DNA-binding regulatory protein for nitrogen fixation. The model produces scores between the trusted and noise cutoffs for a well-described NifA homolog in Aquifex aeolicus (which lacks nitrogenase), for transcriptional activators of alternative nitrogenases (VFe or FeFe instead of MoFe), and truncated forms. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, DNA interactions]
Pssm-ID: 273817 [Multi-domain] Cd Length: 534 Bit Score: 266.58 E-value: 7.62e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 206 IIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGH------- 278
Cdd:TIGR01817 198 IIGKSPAMRQVVDQARVVARSNSTVLLRGESGTGKELIAKAIHYLSPRAKRPFVKVNCAALSETLLESELFGHekgaftg 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 279 APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYY 358
Cdd:TIGR01817 278 AIAQRKGRFELADGGTLFLDEIGEISPAFQAKLLRVLQEGEFERVGGNRTLKVDVRLVAATNRDLEEAVAKGEFRADLYY 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 359 RLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGvpRP-KLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRP 437
Cdd:TIGR01817 358 RINVVPIFLPPLRERREDIPLLAEAFLEKFNRENG--RPlTITPSAIRVLMSCKWPGNVRELENCLERTATLSRSGTITR 435
|
....*
gi 447158237 438 QDILL 442
Cdd:TIGR01817 436 SDFSC 440
|
|
| RNA_repair_RtcR |
NF038308 |
RNA repair transcriptional activator RtcR; |
190-506 |
8.93e-82 |
|
RNA repair transcriptional activator RtcR;
Pssm-ID: 468466 [Multi-domain] Cd Length: 527 Bit Score: 263.66 E-value: 8.93e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 190 QQLQNLSTQDLS-AFSQIIAVSAKMKHVVEQARKLAMLS-APLLITGDTGTGKDLFAYACHQASPRS---AKPYLALNCA 264
Cdd:NF038308 164 QRFAREQAEAVSfLKSGIATRNAAFNRLIEQIERVALRSrAPILLTGPTGAGKSFLARRIYELKKRRhqvSGPFVEVNCA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 265 SIPEDAVESELFGH-------APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVIC 337
Cdd:NF038308 244 TLRGDLAMSELFGHvkgaftgAQADRAGLLRAADGGTLFLDEIGELGLDEQAMLLRAIEEKRFLPVGSDKEVSSDFQLIA 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 338 ATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVP-RPKLSADLST----VLTRYGW 412
Cdd:NF038308 324 GTNRDLRQEVAEGRFREDLYARINLWTFRLPGLRERREDIEPNLDYELDRFARELGRQvRFNKEARFRYlafaTSPEALW 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 413 PGNVRQLKNAIYRALT------------QLEGYELRP--QDILLPDYDAATVAVGEDAMEGSLDditsRFERSVLTQLY- 477
Cdd:NF038308 404 PGNFRELSASVTRMATladggriteelvEEEIARLRAawQSAPAAADDDALADLLGGEQLAELD----LFDRVQLAAVLr 479
|
330 340 350
....*....|....*....|....*....|....*..
gi 447158237 478 --RSYPSTRKLAKRL-GVSHTAIAN-----KLREYGL 506
Cdd:NF038308 480 vcRQSRSLSAAGRRLfGVSRQQKASpndadRLRKYLA 516
|
|
| ACT_TyrR |
cd04877 |
N-terminal ACT domain of the TyrR protein; ACT_TyrR: N-terminal ACT domain of the TyrR protein. ... |
1-74 |
4.58e-37 |
|
N-terminal ACT domain of the TyrR protein; ACT_TyrR: N-terminal ACT domain of the TyrR protein. The TyrR protein of Escherichia coli controls the expression of a group of transcription units (TyrR regulon) whose gene products are involved in the biosynthesis or transport of the aromatic amino acids. Binding to specific DNA sequences known as TyrR boxes, the TyrR protein can either activate or repress transcription at different sigma70 promoters. Its regulatory activity occurs in response to intracellular levels of tyrosine, phenylalanine and tryptophan. The TyrR protein consists of an N-terminal region important for transcription activation with an ATP-independent aromatic amino acid binding site (contained within the ACT domain) and is involved in dimerization; a central region with an ATP binding site, an ATP-dependent aromatic amino acid binding site and is involved in hexamerization; and a helix turn helix DNA binding C-terminal region. In solution, in the absence of cofactors or in the presence of phenylalanine alone, the TyrR protein exists as a dimer. However, in the presence of ATP and tyrosine the TyrR protein self-aggregates to form a hexamer. Members of this CD belong to the superfamily of ACT regulatory domains.
Pssm-ID: 153149 [Multi-domain] Cd Length: 74 Bit Score: 131.24 E-value: 4.58e-37
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447158237 1 MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTDFSSLMAEIRRISGVTDVRTVPWMP 74
Cdd:cd04877 1 MRLEITCEDRLGITQEVLDLLVEHNIDLRGIEIDPKGRIYLNFPTIEFEKLQTLMPEIRRIDGVEDVKTVPYMP 74
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
229-360 |
1.12e-08 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 53.92 E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 229 PLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAPEGK---------KGFFEQANGGS---VL 296
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKasgsgelrlRLALALARKLKpdvLI 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447158237 297 LDEIGEMSPRMQAKLLRFLNDgtfRRVGEDHEIHVDVRVICATQ--KNLVELVQKGLFREDLYYRL 360
Cdd:smart00382 84 LDEITSLLDAEQEALLLLLEE---LRLLLLLKSEKNLTVILTTNdeKDLGPALLRRRFDRRIVLLL 146
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10820 |
PRK10820 |
transcriptional regulator TyrR; |
1-513 |
0e+00 |
|
transcriptional regulator TyrR;
Pssm-ID: 236769 [Multi-domain] Cd Length: 520 Bit Score: 1098.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 1 MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTDFSSLMAEIRRISGVTDVRTVPWMPSEREHL 80
Cdd:PRK10820 1 MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFESFSSLMAEIRRIAGVTDVRTVPFMPSEREHR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 81 ALSALLEALPEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNPQSSHNEHVVINGQNFLME 160
Cdd:PRK10820 81 ALSALLEALPEPVLSIDMKGKVELANPASCQLFGQSEEKLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQDFLME 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 161 ITPVHLQNENDEYVLTGAVVMLRSTIRMGQQLQNLSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGK 240
Cdd:PRK10820 161 ITPVYLQDENDQHVLVGAVVMLRSTARMGRQLQNLAVNDDSAFSQIVAVSPKMRQVVEQARKLAMLDAPLLITGDTGTGK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 241 DLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAP-------EGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLR 313
Cdd:PRK10820 241 DLLAYACHLRSPRGKKPFLALNCASIPDDVVESELFGHAPgaypnalEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 314 FLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQG 393
Cdd:PRK10820 321 FLNDGTFRRVGEDHEVHVDVRVICATQKNLVELVQKGEFREDLYYRLNVLTLNLPPLRDRPQDIMPLTELFVARFADEQG 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 394 VPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAAtVAVGEDAMEGSLDDITSRFERSVL 473
Cdd:PRK10820 401 VPRPKLAADLNTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAA-VAVGEDAMEGSLDEITSRFERSVL 479
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 447158237 474 TQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQKKGEE 513
Cdd:PRK10820 480 TRLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQKKGEE 519
|
|
| TyrR |
COG3283 |
Transcriptional regulator TyrR of aromatic amino acids metabolism [Transcription, Amino acid ... |
1-508 |
0e+00 |
|
Transcriptional regulator TyrR of aromatic amino acids metabolism [Transcription, Amino acid transport and metabolism];
Pssm-ID: 442513 [Multi-domain] Cd Length: 514 Bit Score: 946.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 1 MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTDFSSLMAEIRRISGVTDVRTVPWMPSEREHL 80
Cdd:COG3283 1 MRLEVTCEDRLGITRELLDLLVERNIDLRGIEIDPSGRIYLNFPELDFEQFQHLMPEIRRIPGVTDVRTVPFMPSEREHL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 81 ALSALLEALPEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNPQSSHNEHVVINGQNFLME 160
Cdd:COG3283 81 ELDALLEALPDPVFSIDLKGKIELANPAALSLLGLSEEELIGQPLSELLKGFNFSRWLESNEPRPQSERVVINGQDYLAD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 161 ITPVHLQNENDEYVLTGAVVMLRSTIRMGQQLQNLSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGK 240
Cdd:COG3283 161 ILPIYLPDEEGKSILAGAVVTLKSAARLGEQLQALQVNDDSGFDHIVASSPKMRQVIRQAKKMAMLDAPLLIQGETGTGK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 241 DLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAP-------EGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLR 313
Cdd:COG3283 241 ELLARACHLASPRGDKPFLALNCAALPDDVAESELFGYAPgafgnarEGKKGLFEQANGGTVFLDEIGEMSPQLQAKLLR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 314 FLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQG 393
Cdd:COG3283 321 FLQDGTFRRVGEEQEVKVDVRVICATQKDLAELVQEGEFREDLYYRLNVLTLTLPPLRERKSDILPLAEHFVARFSQQLG 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 394 VPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAAtVAVGEDAMEGSLDDITSRFERSVL 473
Cdd:COG3283 401 RPRPRLSPDLVDFLQSYPWPGNVRQLENALYRAVSLLEGDELTPEDLQLPEYAAS-AGLLDDLLEGSLDEIVKRFERSLL 479
|
490 500 510
....*....|....*....|....*....|....*
gi 447158237 474 TQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQ 508
Cdd:COG3283 480 RRLYPSYPSTRKLAKRLGVSHTAIANKLREYGIGK 514
|
|
| RocR |
COG3829 |
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis ... |
90-507 |
2.95e-143 |
|
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 443041 [Multi-domain] Cd Length: 448 Bit Score: 419.18 E-value: 2.95e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 90 PEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWL-DGNPQSSHNEHVVINGQNFLMEITPVHLQN 168
Cdd:COG3829 21 DDGIIVVDADGRITYVNRAAERILGLPREEVIGKNVTELIPNSPLLEVLkTGKPVTGVIQKTGGKGKTVIVTAIPIFEDG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 169 EndeyvLTGAVVMLRSTIRMGQQLQNLSTQDLS-------AFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKD 241
Cdd:COG3829 101 E-----VIGAVETFRDITELKRLERKLREEELErglsakyTFDDIIGKSPAMKELLELAKRVAKSDSTVLILGESGTGKE 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 242 LFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAP--------EGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLR 313
Cdd:COG3829 176 LFARAIHNASPRRDGPFVAVNCAAIPENLLESELFGYEKgaftgakkGGKPGLFELADGGTLFLDEIGEMPLSLQAKLLR 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 314 FLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQG 393
Cdd:COG3829 256 VLQEKEVRRVGGTKPIPVDVRIIAATNRDLEEMVEEGRFREDLYYRLNVIPIHIPPLRERKEDIPLLAEHFLEKFNKKYG 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 394 VPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDilLPDYDAATVAVGEDAMEGSLDDITSRFERSVL 473
Cdd:COG3829 336 KNIKGISPEALELLLAYDWPGNVRELENVIERAVVLSEGDVITPEH--LPEYLLEEAEAASAAEEGSLKEALEEVEKELI 413
|
410 420 430
....*....|....*....|....*....|....*
gi 447158237 474 TQLYRSYPSTR-KLAKRLGVSHTAIANKLREYGLS 507
Cdd:COG3829 414 EEALEKTGGNKsKAAKALGISRSTLYRKLKKYGIK 448
|
|
| AtoC |
COG2204 |
DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, ... |
182-505 |
7.40e-109 |
|
DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains [Signal transduction mechanisms];
Pssm-ID: 441806 [Multi-domain] Cd Length: 418 Bit Score: 330.39 E-value: 7.40e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 182 LRSTIRMGQQLQNLStQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLAL 261
Cdd:COG2204 110 LLAAVERALERRRLR-RENAEDSGLIGRSPAMQEVRRLIEKVAPSDATVLITGESGTGKELVARAIHRLSPRADGPFVAV 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 262 NCASIPEDAVESELFGH-------APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVR 334
Cdd:COG2204 189 NCAAIPEELLESELFGHekgaftgAVARRIGKFELADGGTLFLDEIGEMPLALQAKLLRVLQEREFERVGGNKPIPVDVR 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 335 VICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPrPKLSADLSTVLTRYGWPG 414
Cdd:COG2204 269 VIAATNRDLEELVEEGRFREDLYYRLNVFPIELPPLRERREDIPLLARHFLARFAAELGKP-VKLSPEALEALLAYDWPG 347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 415 NVRQLKNAIYRALTQLEGYELRPQDillpdydaatvavgedamegsLDDITSRFERS-VLTQLYRSYPSTRKLAKRLGVS 493
Cdd:COG2204 348 NVRELENVIERAVILADGEVITAED---------------------LPEALEEVERElIERALEETGGNVSRAAELLGIS 406
|
330
....*....|..
gi 447158237 494 HTAIANKLREYG 505
Cdd:COG2204 407 RRTLYRKLKKYG 418
|
|
| AcoR |
COG3284 |
Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription]; |
90-505 |
1.76e-107 |
|
Transcriptional regulator DhaR of acetoin/glycerol metabolism [Transcription];
Pssm-ID: 442514 [Multi-domain] Cd Length: 625 Bit Score: 333.41 E-value: 1.76e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 90 PEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLInGFNFQRWLDGNPQSShnehvvingqnflMEITPVHLQNE 169
Cdd:COG3284 226 SEGLLAFDEDGRIVAANRAARRLLGLADAALLGRPLEELF-GLDLEALPDGARRAP-------------ASPRPLRLRDG 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 170 NdeyvLTGAVVMLRSTIRMGQQlQNLSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQ 249
Cdd:COG3284 292 R----RLGALLRLRPARRAARA-APAGAPAPAALAALAGGDPAMRRALRRARRLADRDIPVLILGETGTGKELFARAIHA 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 250 ASPRSAKPYLALNCASIPEDAVESELFGHAP--------EGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFR 321
Cdd:COG3284 367 ASPRADGPFVAVNCAAIPEELIESELFGYEPgaftgarrKGRPGKIEQADGGTLFLDEIGDMPLALQARLLRVLQEREVT 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 322 RVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDcPQDIMPLTELFVARFADEQGVPRpkLSA 401
Cdd:COG3284 447 PLGGTKPIPVDVRLIAATHRDLRELVAAGRFREDLYYRLNGLTLTLPPLRE-REDLPALIEHLLRELAAGRGPLR--LSP 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 402 DLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDilLPDY---DAATVAVGEDAMEGSLDDItsrfERSVLTQLYR 478
Cdd:COG3284 524 EALALLAAYPWPGNVRELRNVLRTALALADGGVITVED--LPDElraELAAAAPAAAAPLTSLEEA----ERDAILRALR 597
|
410 420 430
....*....|....*....|....*....|.
gi 447158237 479 sypSTR----KLAKRLGVSHTAIANKLREYG 505
Cdd:COG3284 598 ---ACGgnvsAAARALGISRSTLYRKLKRYG 625
|
|
| Sigma54_activat |
pfam00158 |
Sigma-54 interaction domain; |
206-365 |
4.05e-88 |
|
Sigma-54 interaction domain;
Pssm-ID: 425491 [Multi-domain] Cd Length: 168 Bit Score: 267.73 E-value: 4.05e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 206 IIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGH------- 278
Cdd:pfam00158 1 IIGESPAMQEVLEQAKRVAPTDAPVLITGESGTGKELFARAIHQLSPRADGPFVAVNCAAIPEELLESELFGHekgaftg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 279 APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYY 358
Cdd:pfam00158 81 ADSDRKGLFELADGGTLFLDEIGELPLELQAKLLRVLQEGEFERVGGTKPIKVDVRIIAATNRDLEEAVAEGRFREDLYY 160
|
....*..
gi 447158237 359 RLNVLTL 365
Cdd:pfam00158 161 RLNVIPI 167
|
|
| TF_PrdR |
NF041552 |
sigma-54 dependent transcriptional regulator PrdR; |
203-423 |
8.17e-85 |
|
sigma-54 dependent transcriptional regulator PrdR;
Pssm-ID: 469437 [Multi-domain] Cd Length: 577 Bit Score: 272.92 E-value: 8.17e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 203 FSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAkPYLALNCASIPEDAVESELFGHAP-- 280
Cdd:NF041552 266 FGKIIGKSKKIIKKIEIAKQVAKTNSSVLITGESGTGKEVFARAIHQASGRKG-PFVPVNCSAIPEELFESEFFGYEEga 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 281 ------EGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFRE 354
Cdd:NF041552 345 ftgalkKGKIGKFELANNGTLFLDEIGDMPLSMQAKLLRVLQEKQVRRVGGEKYIKINVRIISATNKDLKKMVKEGKFRE 424
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447158237 355 DLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNAI 423
Cdd:NF041552 425 DLYYRLNVVEIELPPLRERKEDIPLLINYFLKEICKENNKEIPKIDKEVYDILQNYKWKGNIRELKNTI 493
|
|
| nifA |
TIGR01817 |
Nif-specific regulatory protein; This model represents NifA, a DNA-binding regulatory protein ... |
206-442 |
7.62e-83 |
|
Nif-specific regulatory protein; This model represents NifA, a DNA-binding regulatory protein for nitrogen fixation. The model produces scores between the trusted and noise cutoffs for a well-described NifA homolog in Aquifex aeolicus (which lacks nitrogenase), for transcriptional activators of alternative nitrogenases (VFe or FeFe instead of MoFe), and truncated forms. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, DNA interactions]
Pssm-ID: 273817 [Multi-domain] Cd Length: 534 Bit Score: 266.58 E-value: 7.62e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 206 IIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGH------- 278
Cdd:TIGR01817 198 IIGKSPAMRQVVDQARVVARSNSTVLLRGESGTGKELIAKAIHYLSPRAKRPFVKVNCAALSETLLESELFGHekgaftg 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 279 APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYY 358
Cdd:TIGR01817 278 AIAQRKGRFELADGGTLFLDEIGEISPAFQAKLLRVLQEGEFERVGGNRTLKVDVRLVAATNRDLEEAVAKGEFRADLYY 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 359 RLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGvpRP-KLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRP 437
Cdd:TIGR01817 358 RINVVPIFLPPLRERREDIPLLAEAFLEKFNRENG--RPlTITPSAIRVLMSCKWPGNVRELENCLERTATLSRSGTITR 435
|
....*
gi 447158237 438 QDILL 442
Cdd:TIGR01817 436 SDFSC 440
|
|
| RNA_repair_RtcR |
NF038308 |
RNA repair transcriptional activator RtcR; |
190-506 |
8.93e-82 |
|
RNA repair transcriptional activator RtcR;
Pssm-ID: 468466 [Multi-domain] Cd Length: 527 Bit Score: 263.66 E-value: 8.93e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 190 QQLQNLSTQDLS-AFSQIIAVSAKMKHVVEQARKLAMLS-APLLITGDTGTGKDLFAYACHQASPRS---AKPYLALNCA 264
Cdd:NF038308 164 QRFAREQAEAVSfLKSGIATRNAAFNRLIEQIERVALRSrAPILLTGPTGAGKSFLARRIYELKKRRhqvSGPFVEVNCA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 265 SIPEDAVESELFGH-------APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVIC 337
Cdd:NF038308 244 TLRGDLAMSELFGHvkgaftgAQADRAGLLRAADGGTLFLDEIGELGLDEQAMLLRAIEEKRFLPVGSDKEVSSDFQLIA 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 338 ATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVP-RPKLSADLST----VLTRYGW 412
Cdd:NF038308 324 GTNRDLRQEVAEGRFREDLYARINLWTFRLPGLRERREDIEPNLDYELDRFARELGRQvRFNKEARFRYlafaTSPEALW 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 413 PGNVRQLKNAIYRALT------------QLEGYELRP--QDILLPDYDAATVAVGEDAMEGSLDditsRFERSVLTQLY- 477
Cdd:NF038308 404 PGNFRELSASVTRMATladggriteelvEEEIARLRAawQSAPAAADDDALADLLGGEQLAELD----LFDRVQLAAVLr 479
|
330 340 350
....*....|....*....|....*....|....*..
gi 447158237 478 --RSYPSTRKLAKRL-GVSHTAIAN-----KLREYGL 506
Cdd:NF038308 480 vcRQSRSLSAAGRRLfGVSRQQKASpndadRLRKYLA 516
|
|
| PRK11361 |
PRK11361 |
acetoacetate metabolism transcriptional regulator AtoC; |
182-506 |
2.27e-80 |
|
acetoacetate metabolism transcriptional regulator AtoC;
Pssm-ID: 183099 [Multi-domain] Cd Length: 457 Bit Score: 257.85 E-value: 2.27e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 182 LRSTIRMGQQLQNLST------QDLSAFSQ---IIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASP 252
Cdd:PRK11361 112 LNLIVQRALQLQSMKKeirhlhQALSTSWQwghILTNSPAMMDICKDTAKIALSQASVLISGESGTGKELIARAIHYNSR 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 253 RSAKPYLALNCASIPEDAVESELFGH-------APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGE 325
Cdd:PRK11361 192 RAKGPFIKVNCAALPESLLESELFGHekgaftgAQTLRQGLFERANEGTLLLDEIGEMPLVLQAKLLRILQEREFERIGG 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 326 DHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLST 405
Cdd:PRK11361 272 HQTIKVDIRIIAATNRDLQAMVKEGTFREDLFYRLNVIHLILPPLRDRREDISLLANHFLQKFSSENQRDIIDIDPMAMS 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 406 VLTRYGWPGNVRQLKNAIYRALTQLEGY----ELRPQDILLPDYDAATVAVGEDAmEGSLDDITSRFERSVLTQ-LYRSY 480
Cdd:PRK11361 352 LLTAWSWPGNIRELSNVIERAVVMNSGPiifsEDLPPQIRQPVCNAGEVKTAPVG-ERNLKEEIKRVEKRIIMEvLEQQE 430
|
330 340
....*....|....*....|....*.
gi 447158237 481 PSTRKLAKRLGVSHTAIANKLREYGL 506
Cdd:PRK11361 431 GNRTRTALMLGISRRALMYKLQEYGI 456
|
|
| PRK05022 |
PRK05022 |
nitric oxide reductase transcriptional regulator NorR; |
182-494 |
3.05e-78 |
|
nitric oxide reductase transcriptional regulator NorR;
Pssm-ID: 235331 [Multi-domain] Cd Length: 509 Bit Score: 253.94 E-value: 3.05e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 182 LRSTIRMGQ-QLQNLSTQDLSAF--------SQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASP 252
Cdd:PRK05022 156 LRNALLIEQlESQAELPQDVAEFlrqealkeGEMIGQSPAMQQLKKEIEVVAASDLNVLILGETGVGKELVARAIHAASP 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 253 RSAKPYLALNCASIPEDAVESELFGH-------APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGE 325
Cdd:PRK05022 236 RADKPLVYLNCAALPESLAESELFGHvkgaftgAISNRSGKFELADGGTLFLDEIGELPLALQAKLLRVLQYGEIQRVGS 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 326 DHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLST 405
Cdd:PRK05022 316 DRSLRVDVRVIAATNRDLREEVRAGRFRADLYHRLSVFPLSVPPLRERGDDVLLLAGYFLEQNRARLGLRSLRLSPAAQA 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 406 VLTRYGWPGNVRQLKNAIYR----ALTQLEGYE--LRPQDILLPDYDA----ATVAVGEDAMEGSLDDITSRFERSVLTQ 475
Cdd:PRK05022 396 ALLAYDWPGNVRELEHVISRaallARARGAGRIvtLEAQHLDLPAEVAlpppEAAAAPAAVVSQNLREATEAFQRQLIRQ 475
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 447158237 476 ----------------------LYRsypstrkLAKRLGVSH 494
Cdd:PRK05022 476 alaqhqgnwaaaaraleldranLHR-------LAKRLGLKD 509
|
|
| PEP_resp_reg |
TIGR02915 |
PEP-CTERM-box response regulator transcription factor; Members of this protein family share ... |
195-507 |
3.99e-78 |
|
PEP-CTERM-box response regulator transcription factor; Members of this protein family share full-length homology with (but do not include) the acetoacetate metabolism regulatory protein AtoC (see SP|Q06065). These proteins have a Fis family DNA binding sequence (pfam02954), a response regulator receiver domain (pfam00072), and sigma-54 interaction domain (pfam00158). [Regulatory functions, DNA interactions]
Pssm-ID: 274348 [Multi-domain] Cd Length: 445 Bit Score: 251.59 E-value: 3.99e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 195 LSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESE 274
Cdd:TIGR02915 130 QSALGGTALRGLITSSPGMQKICRTIEKIAPSDITVLLLGESGTGKEVLARALHQLSDRKDKRFVAINCAAIPENLLESE 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 275 LFGHapegKKGFF-----------EQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNL 343
Cdd:TIGR02915 210 LFGY----EKGAFtgavkqtlgkiEYAHGGTLFLDEIGDLPLNLQAKLLRFLQERVIERLGGREEIPVDVRIVCATNQDL 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 344 VELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNAI 423
Cdd:TIGR02915 286 KRMIAEGTFREDLFYRIAEISITIPPLRSRDGDAVLLANAFLERFARELKRKTKGFTDDALRALEAHAWPGNVRELENKV 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 424 YRALTQLEGYELRPQDILLPDydaatVAVGEDAMEGSLDDITSRFERSVLTQLY-RSYPSTRKLAKRLGVSHTAIANKLR 502
Cdd:TIGR02915 366 KRAVIMAEGNQITAEDLGLDA-----RERAETPLEVNLREVRERAEREAVRKAIaRVDGNIARAAELLGITRPTLYDLMK 440
|
....*
gi 447158237 503 EYGLS 507
Cdd:TIGR02915 441 KHGIK 445
|
|
| glnG |
PRK10923 |
nitrogen regulation protein NR(I); Provisional |
190-506 |
2.35e-73 |
|
nitrogen regulation protein NR(I); Provisional
Pssm-ID: 182842 [Multi-domain] Cd Length: 469 Bit Score: 240.16 E-value: 2.35e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 190 QQLQNLSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPED 269
Cdd:PRK10923 124 EQQQPRNIQVNGPTTDIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKD 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 270 AVESELFGH-------APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKN 342
Cdd:PRK10923 204 LIESELFGHekgaftgANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQN 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 343 LVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNa 422
Cdd:PRK10923 284 LEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQLEN- 362
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 423 IYRALTQL-EGYELRPQDI---------------LLPDYDAATVAV-GEDAMEGSLDDITSR----FERSVLTQLYRSYP 481
Cdd:PRK10923 363 TCRWLTVMaAGQEVLIQDLpgelfestvpestsqMQPDSWATLLAQwADRALRSGHQNLLSEaqpeLERTLLTTALRHTQ 442
|
330 340
....*....|....*....|....*.
gi 447158237 482 STRKLAKR-LGVSHTAIANKLREYGL 506
Cdd:PRK10923 443 GHKQEAARlLGWGRNTLTRKLKELGM 468
|
|
| phageshock_pspF |
TIGR02974 |
psp operon transcriptional activator PspF; Members of this protein family are PspF, the ... |
216-504 |
1.13e-69 |
|
psp operon transcriptional activator PspF; Members of this protein family are PspF, the sigma-54-dependent transcriptional activator of the phage shock protein (psp) operon, in Escherichia coli and numerous other species. The psp operon is induced by a number of stress conditions, including heat shock, ethanol, and filamentous phage infection. Changed com_name to adhere to TIGR role notes conventions. 09/15/06 - DMH [Regulatory functions, DNA interactions]
Pssm-ID: 274371 [Multi-domain] Cd Length: 329 Bit Score: 226.02 E-value: 1.13e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 216 VVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGH-------APEGKKGFFE 288
Cdd:TIGR02974 11 VLEQVSRLAPLDRPVLIIGERGTGKELIAARLHYLSKRWQGPLVKLNCAALSENLLDSELFGHeagaftgAQKRHQGRFE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 289 QANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLP 368
Cdd:TIGR02974 91 RADGGTLFLDELATASLLVQEKLLRVIEYGEFERVGGSQTLQVDVRLVCATNADLPALAAEGRFRADLLDRLAFDVITLP 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 369 PLRDCPQDIMPLTELFVARFADEQGVPR-PKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILL----- 442
Cdd:TIGR02974 171 PLRERQEDIMLLAEHFAIRMARELGLPLfPGFTPQAREQLLEYHWPGNVRELKNVVERSVYRHGLEEAPIDEIIIdpfas 250
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447158237 443 -----PDYDAATVAVGEDAMEGSLDDITS-----------RFERSVLTQ-LYRSYPSTRKLAKRLGVSHTAIANKLREY 504
Cdd:TIGR02974 251 pwrpkQAAPAVDEVNSTPTDLPSPSSIAAafpldlkqaqqDYEIELLQQaLAEAQFNQRKAAELLGLTYHQLRGLLRKH 329
|
|
| PRK10365 |
PRK10365 |
sigma-54-dependent response regulator transcription factor ZraR; |
206-501 |
2.03e-64 |
|
sigma-54-dependent response regulator transcription factor ZraR;
Pssm-ID: 182412 [Multi-domain] Cd Length: 441 Bit Score: 215.66 E-value: 2.03e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 206 IIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGH------- 278
Cdd:PRK10365 141 MVGKSPAMQHLLSEIALVAPSEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHekgaftg 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 279 APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYY 358
Cdd:PRK10365 221 ADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQTISVDVRLIAATHRDLAAEVNAGRFRQDLYY 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 359 RLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQ 438
Cdd:PRK10365 301 RLNVVAIEVPSLRQRREDIPLLAGHFLQRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISER 380
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447158237 439 DILLPDYDAATVAVGEDAMEGSLDditsrFERSV-LTQLYRSYPSTRKLAKRLGVSHTAIANKL 501
Cdd:PRK10365 381 ELPLAIASTPIPLGQSQDIQPLVE-----VEKEViLAALEKTGGNKTEAARQLGITRKTLLAKL 439
|
|
| propionate_PrpR |
TIGR02329 |
propionate catabolism operon regulatory protein PrpR; At least five distinct pathways exists ... |
206-501 |
2.45e-62 |
|
propionate catabolism operon regulatory protein PrpR; At least five distinct pathways exists for the catabolism of propionate by way of propionyl-CoA. Members of this family represent the transcriptional regulatory protein PrpR, whose gene is found in most cases divergently transcribed from an operon for the methylcitric acid cycle of propionate catabolism. 2-methylcitric acid, a catabolite by this pathway, is a coactivator of PrpR. [Regulatory functions, DNA interactions]
Pssm-ID: 274079 [Multi-domain] Cd Length: 526 Bit Score: 212.41 E-value: 2.45e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 206 IIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAPE---- 281
Cdd:TIGR02329 214 LLGASAPMEQVRALVRLYARSDATVLILGESGTGKELVAQAIHQLSGRRDFPFVAINCGAIAESLLEAELFGYEEGaftg 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 282 ----GKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLY 357
Cdd:TIGR02329 294 arrgGRTGLIEAAHRGTLFLDEIGEMPLPLQTRLLRVLEEREVVRVGGTEPVPVDVRVVAATHCALTTAVQQGRFRRDLF 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 358 YRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVP----RPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGy 433
Cdd:TIGR02329 374 YRLSILRIALPPLRERPGDILPLAAEYLVQAAAALRLPdseaAAQVLAGVADPLQRYPWPGNVRELRNLVERLALELSA- 452
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447158237 434 elRPQDILLPDYDAATVAVGEDAMEGSLDDITSRFERSVLTQLyrsypSTRKLAKRLGVSHTAIANKL 501
Cdd:TIGR02329 453 --MPAGALTPDVLRALAPELAEASGKGKTSALSLRERSRVEAL-----AVRAALERFGGDRDAAAKAL 513
|
|
| FhlA |
COG3604 |
FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis ... |
218-507 |
2.67e-61 |
|
FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 442823 [Multi-domain] Cd Length: 338 Bit Score: 204.31 E-value: 2.67e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 218 EQARKLAMLSAPL--LITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESelfghapegkkgffeqanggsv 295
Cdd:COG3604 104 EDLRLLETLASLAavAILGETGTGKELVANAIHELSPRADKPFVKVNCAALPESLLES---------------------- 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 296 lldeigemsprmqakllrfLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQ 375
Cdd:COG3604 162 -------------------LQEGEFERVGGDETIKVDVRIIAATNRDLEEEVAEGRFREDLYYRLNVFPIRLPPLRERRE 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 376 DIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAatvavged 455
Cdd:COG3604 223 DIPLLAEHFLEKFSRRLGKPILRLSPEALEALMAYPWPGNVRELENVIERAVILAEGGVLDADDLAPGSREA-------- 294
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 447158237 456 amegslddiTSRFERSVLTQ-LYRSYPSTRKLAKRLGVSHTAIANKLREYGLS 507
Cdd:COG3604 295 ---------LEEVEREHILEaLERTGGNIAGAARLLGLTPSTLRSRMKKLGIK 338
|
|
| PRK15115 |
PRK15115 |
response regulator GlrR; Provisional |
205-428 |
2.02e-60 |
|
response regulator GlrR; Provisional
Pssm-ID: 185070 [Multi-domain] Cd Length: 444 Bit Score: 205.46 E-value: 2.02e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 205 QIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAP---- 280
Cdd:PRK15115 135 AIVTRSPLMLRLLEQARMVAQSDVSVLINGQSGTGKEILAQAIHNASPRASKPFIAINCGALPEQLLESELFGHARgaft 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 281 ---EGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLY 357
Cdd:PRK15115 215 gavSNREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISATHRDLPKAMARGEFREDLY 294
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447158237 358 YRLNVLTLNLPPLRDCPQDImPLTELFVARFADEQGVPRPK-LSADLSTVLTRYGWPGNVRQLKNAIYR--ALT 428
Cdd:PRK15115 295 YRLNVVSLKIPALAERTEDI-PLLANHLLRQAAERHKPFVRaFSTDAMKRLMTASWPGNVRQLVNVIEQcvALT 367
|
|
| PRK15424 |
PRK15424 |
propionate catabolism operon regulatory protein PrpR; Provisional |
210-508 |
1.97e-59 |
|
propionate catabolism operon regulatory protein PrpR; Provisional
Pssm-ID: 237963 [Multi-domain] Cd Length: 538 Bit Score: 204.95 E-value: 1.97e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 210 SAKMKHVveqaRKLAMLSAP----LLITGDTGTGKDLFAYACHQASP--------RSAKPYLALNCASIPEDAVESELFG 277
Cdd:PRK15424 225 SPQMEQV----RQTILLYARssaaVLIQGETGTGKELAAQAIHREYFarhdarqgKKSHPFVAVNCGAIAESLLEAELFG 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 278 HAPE--------GKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQK 349
Cdd:PRK15424 301 YEEGaftgsrrgGRAGLFEIAHGGTLFLDEIGEMPLPLQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCDLEEDVRQ 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 350 GLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVP-RPKLSADLST---VLTRYGWPGNVRQLKNAIYR 425
Cdd:PRK15424 381 GRFRRDLFYRLSILRLQLPPLRERVADILPLAESFLKQSLAALSAPfSAALRQGLQQcetLLLHYDWPGNVRELRNLMER 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 426 ALTQLEGyelRPQDILLPDY---------DAATVAVGEDAMEGSLDDITSRFErsvltqlyrsypSTRKLAKR-LGVSHT 495
Cdd:PRK15424 461 LALFLSV---EPTPDLTPQFlqlllpelaRESAKTPAPRLLAATLQQALERFN------------GDKTAAANyLGISRT 525
|
330
....*....|...
gi 447158237 496 AIANKLREYGLSQ 508
Cdd:PRK15424 526 TLWRRLKAEAKAQ 538
|
|
| PRK15429 |
PRK15429 |
formate hydrogenlyase transcriptional activator FlhA; |
190-506 |
2.24e-56 |
|
formate hydrogenlyase transcriptional activator FlhA;
Pssm-ID: 237965 [Multi-domain] Cd Length: 686 Bit Score: 199.67 E-value: 2.24e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 190 QQLQNLStqdlSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPED 269
Cdd:PRK15429 366 EQLNNVD----SEFGEIIGRSEAMYSVLKQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAG 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 270 AVESELFGH-------APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKN 342
Cdd:PRK15429 442 LLESDLFGHergaftgASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSNKIIQTDVRLIAATNRD 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 343 LVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNA 422
Cdd:PRK15429 522 LKKMVADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLVKAFTFKIARRMGRNIDSIPAETLRTLSNMEWPGNVRELENV 601
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 423 IYRA--LTQLEGYELRPQDILLPDYDAATVAVgEDAMEGslDDITSRFERsVLTQLYRSYPSTRKLAKRLGVSHTAIANK 500
Cdd:PRK15429 602 IERAvlLTRGNVLQLSLPDITLPEPETPPAAT-VVAQEG--EDEYQLIVR-VLKETNGVVAGPKGAAQRLGLKRTTLLSR 677
|
....*.
gi 447158237 501 LREYGL 506
Cdd:PRK15429 678 MKRLGI 683
|
|
| pspF |
PRK11608 |
phage shock protein operon transcriptional activator; Provisional |
216-427 |
6.20e-56 |
|
phage shock protein operon transcriptional activator; Provisional
Pssm-ID: 236936 [Multi-domain] Cd Length: 326 Bit Score: 189.88 E-value: 6.20e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 216 VVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGH-------APEGKKGFFE 288
Cdd:PRK11608 18 VLEQVSRLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHeagaftgAQKRHPGRFE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 289 QANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLP 368
Cdd:PRK11608 98 RADGGTLFLDELATAPMLVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVAEGKFRADLLDRLAFDVVQLP 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 369 PLRDCPQDIMPLTELFVARFADEQGVPR-PKLSADLSTVLTRYGWPGNVRQLKNAIYRAL 427
Cdd:PRK11608 178 PLRERQSDIMLMAEHFAIQMCRELGLPLfPGFTERARETLLNYRWPGNIRELKNVVERSV 237
|
|
| PRK11388 |
PRK11388 |
DNA-binding transcriptional regulator DhaR; Provisional |
191-511 |
2.20e-51 |
|
DNA-binding transcriptional regulator DhaR; Provisional
Pssm-ID: 183114 [Multi-domain] Cd Length: 638 Bit Score: 185.27 E-value: 2.20e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 191 QLQNLSTQDLS----AFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASI 266
Cdd:PRK11388 308 QMRQLMTSQLGkvshTFDHMPQDSPQMRRLIHFGRQAAKSSFPVLLCGEEGVGKALLAQAIHNESERAAGPYIAVNCQLY 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 267 PEDAVESELFGHAP----EGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKN 342
Cdd:PRK11388 388 PDEALAEEFLGSDRtdseNGRLSKFELAHGGTLFLEKVEYLSPELQSALLQVLKTGVITRLDSRRLIPVDVRVIATTTAD 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 343 LVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVpRPKLSADLSTVLTRYGWPGNVRQLKNA 422
Cdd:PRK11388 468 LAMLVEQNRFSRQLYYALHAFEITIPPLRMRREDIPALVNNKLRSLEKRFST-RLKIDDDALARLVSYRWPGNDFELRSV 546
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 423 IYRALTQLEGYELRPQDilLPDYDAATVAVGEDAMEGSLDDIT-SRFERSVLTQLYR-SYPSTRKLAKRLGVSHTAIANK 500
Cdd:PRK11388 547 IENLALSSDNGRIRLSD--LPEHLFTEQATDDVSATRLSTSLSlAELEKEAIINAAQvCGGRIQEMAALLGIGRTTLWRK 624
|
330
....*....|...
gi 447158237 501 LREYGL--SQKKG 511
Cdd:PRK11388 625 MKQHGIdaGQFKR 637
|
|
| ACT_TyrR |
cd04877 |
N-terminal ACT domain of the TyrR protein; ACT_TyrR: N-terminal ACT domain of the TyrR protein. ... |
1-74 |
4.58e-37 |
|
N-terminal ACT domain of the TyrR protein; ACT_TyrR: N-terminal ACT domain of the TyrR protein. The TyrR protein of Escherichia coli controls the expression of a group of transcription units (TyrR regulon) whose gene products are involved in the biosynthesis or transport of the aromatic amino acids. Binding to specific DNA sequences known as TyrR boxes, the TyrR protein can either activate or repress transcription at different sigma70 promoters. Its regulatory activity occurs in response to intracellular levels of tyrosine, phenylalanine and tryptophan. The TyrR protein consists of an N-terminal region important for transcription activation with an ATP-independent aromatic amino acid binding site (contained within the ACT domain) and is involved in dimerization; a central region with an ATP binding site, an ATP-dependent aromatic amino acid binding site and is involved in hexamerization; and a helix turn helix DNA binding C-terminal region. In solution, in the absence of cofactors or in the presence of phenylalanine alone, the TyrR protein exists as a dimer. However, in the presence of ATP and tyrosine the TyrR protein self-aggregates to form a hexamer. Members of this CD belong to the superfamily of ACT regulatory domains.
Pssm-ID: 153149 [Multi-domain] Cd Length: 74 Bit Score: 131.24 E-value: 4.58e-37
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447158237 1 MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTDFSSLMAEIRRISGVTDVRTVPWMP 74
Cdd:cd04877 1 MRLEITCEDRLGITQEVLDLLVEHNIDLRGIEIDPKGRIYLNFPTIEFEKLQTLMPEIRRIDGVEDVKTVPYMP 74
|
|
| RtcR |
COG4650 |
Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a ... |
217-432 |
1.18e-34 |
|
Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription, Signal transduction mechanisms];
Pssm-ID: 443688 [Multi-domain] Cd Length: 534 Bit Score: 136.50 E-value: 1.18e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 217 VEQARKLAMLS-APLLITGDTGTGKDLFA---YACHQASPRSAKPYLALNCASIPEDAVESELFGH-------APEGKKG 285
Cdd:COG4650 197 IEQIERVAIRSrAPILLTGPTGAGKSQLArriYELKKARHQVSGRFVEVNCATLRGDGAMSALFGHvkgaftgAVSDRAG 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 286 FFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTL 365
Cdd:COG4650 277 LLRSADGGVLFLDEIGELGLDEQAMLLRAIEEKRFLPVGSDKEVSSDFQLIAGTNRDLRQEVAEGRFREDLLARINLWTF 356
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 447158237 366 NLPPLRDCPQDIMPLTELFVARFADEQGVpRPKLSADLSTVLTRYG------WPGNVRQLKNAIYRALTQLEG 432
Cdd:COG4650 357 RLPGLAERREDIEPNLDYELARFAREQGR-RVRFNKEARARYLAFAtspealWSGNFRDLNASVTRMATLAEG 428
|
|
| PspF |
COG1221 |
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain ... |
201-423 |
4.00e-28 |
|
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription, Signal transduction mechanisms];
Pssm-ID: 440834 [Multi-domain] Cd Length: 835 Bit Score: 118.67 E-value: 4.00e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 201 SAFSQIIAVSAKMKHVVEQArKLAMLSAP----LLITGDTGTGKDLFA-----YACHQASPRSAKPYLALNCA---SIPE 268
Cdd:COG1221 101 DPFDNLIGANGSLKNAIEQA-KAAILYPPkglhTLILGPTGVGKSFFAelmyeYAIEIGVLPEDAPFVVFNCAdyaNNPQ 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 269 dAVESELFGH-------APEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGE-DHEIHVDVRVICATQ 340
Cdd:COG1221 180 -LLMSQLFGYvkgaftgADKDKEGLIEKADGGILFLDEVHRLPPEGQEMLFTFMDKGIYRRLGEtEKTRKANVRIIFATT 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 341 KNLVELVQKGLFRedlyyRLNVlTLNLPPLRDCP-QDIMPLTELFvarFADE-QGVPRP-KLSADLSTVLTRYGWPGNVR 417
Cdd:COG1221 259 EDPESSLLKTFLR-----RIPM-VIKLPSLEERSlEERLELIKHF---FKEEaKRLNKPiKVSKEVLKALLLYDCPGNIG 329
|
....*.
gi 447158237 418 QLKNAI 423
Cdd:COG1221 330 QLKSDI 335
|
|
| HTH_TypR |
TIGR04381 |
TyrR family helix-turn-helix domain; This model describes the C-terminal DNA-binding ... |
460-508 |
1.34e-26 |
|
TyrR family helix-turn-helix domain; This model describes the C-terminal DNA-binding helix-turn-helix domain of several regulators of aromatic amino acid metabolism. Examples include TyrR in Escherichia coli and PhhR in Pseudomonas putida. Most members of this family have a sigma-54 interaction domain. [Regulatory functions, DNA interactions]
Pssm-ID: 275174 [Multi-domain] Cd Length: 49 Bit Score: 101.67 E-value: 1.34e-26
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 447158237 460 SLDDITSRFERSVLTQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQ 508
Cdd:TIGR04381 1 SLDEIMKRFEASLLRRLYASYPSTRQLAKRLGVSHTAIANKLREYGIGK 49
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
213-361 |
3.86e-24 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 98.37 E-value: 3.86e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 213 MKHVVEQARKLAMLS--APLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGH-APEGKKGFFEQ 289
Cdd:cd00009 3 QEEAIEALREALELPppKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHfLVRLLFELAEK 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 447158237 290 ANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRvgedhEIHVDVRVICATQKNLvelvqKGLFREDLYYRLN 361
Cdd:cd00009 83 AKPGVLFIDEIDSLSRGAQNALLRVLETLNDLR-----IDRENVRVIGATNRPL-----LGDLDRALYDRLD 144
|
|
| Sigma54_activ_2 |
pfam14532 |
Sigma-54 interaction domain; |
207-370 |
5.53e-18 |
|
Sigma-54 interaction domain;
Pssm-ID: 434021 [Multi-domain] Cd Length: 138 Bit Score: 80.46 E-value: 5.53e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 207 IAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFA-YACHQASPRSAkPYLALNCASIPEDaveselfghapegkkg 285
Cdd:pfam14532 1 LGASAAIQEIKRRLEQAAQSTLPVFLTGEPGSGKEFCArYLHNPSTPWVQ-PFDIEYLAHAPLE---------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 286 FFEQANGGSVLLDEIGEMSPRMQAKLLRFLndgtfrRVGEDHeihvDVRVICATQKNLVELVQKGLFREDLYYRLNVLTL 365
Cdd:pfam14532 64 LLEQAKGGTLYLKDIADLSKALQKGLLLLL------AKAEGY----RVRLVCTSSKDLPQLAAAGLFDEQLYFELSALRL 133
|
....*
gi 447158237 366 NLPPL 370
Cdd:pfam14532 134 HVPPL 138
|
|
| HTH_50 |
pfam18024 |
Helix-turn-helix domain; The TyrR protein of Haemophilus influenzae is a 36-kD transcription ... |
458-507 |
3.38e-15 |
|
Helix-turn-helix domain; The TyrR protein of Haemophilus influenzae is a 36-kD transcription factor whose major function is to control the expression of genes important in the biosynthesis and transport of aromatic amino acids. This entry represents the C-terminal helix-turn-helix DNA-binding domain of TyrR and related proteins.
Pssm-ID: 407862 [Multi-domain] Cd Length: 50 Bit Score: 69.75 E-value: 3.38e-15
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 447158237 458 EGSLDDITSRFERSVLTQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLS 507
Cdd:pfam18024 1 EMSLKEYVSYIERELIGAAYENYKSARKVAKALGLSHTTIANKMKRYGIS 50
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
229-360 |
1.12e-08 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 53.92 E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 229 PLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAPEGK---------KGFFEQANGGS---VL 296
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKasgsgelrlRLALALARKLKpdvLI 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447158237 297 LDEIGEMSPRMQAKLLRFLNDgtfRRVGEDHEIHVDVRVICATQ--KNLVELVQKGLFREDLYYRL 360
Cdd:smart00382 84 LDEITSLLDAEQEALLLLLEE---LRLLLLLKSEKNLTVILTTNdeKDLGPALLRRRFDRRIVLLL 146
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
90-193 |
1.36e-04 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 44.07 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 90 PEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFN-----FQRWLDGNPQSSHNE--HVVINGQNFLMEIT 162
Cdd:COG3852 17 PDAVIVLDADGRITYVNPAAERLLGLSAEELLGRPLAELFPEDSplrelLERALAEGQPVTEREvtLRRKDGEERPVDVS 96
|
90 100 110
....*....|....*....|....*....|....
gi 447158237 163 PVHLQNENDEyvlTGAVVMLR---STIRMGQQLQ 193
Cdd:COG3852 97 VSPLRDAEGE---GGVLLVLRditERKRLERELR 127
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
93-162 |
2.52e-03 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 40.06 E-value: 2.52e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447158237 93 VLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNP----QSSHNEHV--VINGQNFLMEIT 162
Cdd:PRK11073 20 ILLLDDDLAIHYANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIELMRESlqagQGFTDNEVtlVIDGRSHILSLT 95
|
|
| PAS |
smart00091 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
90-139 |
3.82e-03 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels.
Pssm-ID: 214512 Cd Length: 67 Bit Score: 35.84 E-value: 3.82e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 447158237 90 PEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLD 139
Cdd:smart00091 11 PDGIFVLDLDGRILYANPAAEELLGYSPEELIGKSLLELIHPEDRERVQE 60
|
|
| PAS |
cd00130 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
90-175 |
3.97e-03 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction.
Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 36.84 E-value: 3.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447158237 90 PEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLD--------GNPQSSHNEHVVINGQNF--LM 159
Cdd:cd00130 2 PDGVIVLDLDGRILYANPAAEQLLGYSPEELIGKSLLDLIHPEDREELRErlenllsgGEPVTLEVRLRRKDGSVIwvLV 81
|
90
....*....|....*.
gi 447158237 160 EITPVHLQNENDEYVL 175
Cdd:cd00130 82 SLTPIRDEGGEVIGLL 97
|
|
| |
