|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09694 |
PRK09694 |
CRISPR-associated helicase/endonuclease Cas3; |
16-782 |
2.06e-129 |
|
CRISPR-associated helicase/endonuclease Cas3;
Pssm-ID: 182031 [Multi-domain] Cd Length: 878 Bit Score: 410.35 E-value: 2.06e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 16 TFFDFWGKTRRgEKDGGDDYHLLCWHSLDVAAmgylmvkrncfgLADYF--------RQLGISDKEQAAQFFAWLLCW-- 85
Cdd:PRK09694 6 YYCRYWGKASK-SLTKGNDYHLLPYHCLDVAA------------VADCWwdqspvlrSQFSANEMLSKQQVRAWLLFFva 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 86 -HDIGKFARSFQ-------QLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMP 157
Cdd:PRK09694 73 lHDIGKFDIRFQykapeiwLKLNPAGPSISGPSTQMCRKYDHGAAGLLWFRQDFRSNQASDDSFFDAAPHPYEAWFPWME 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 158 VTTGHHGR------PPDRM----DELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFwdDDEGIELIKHLSWYISatvvLA 227
Cdd:PRK09694 153 AVTGHHGYilhsqdQDDSRwempASLASYAEQDKQAREEWIQALEALFLTPAGLSL--NDIPPPCSPLLAGFCS----VS 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 228 DWTGSSTRFFPRVAH--PMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLdisQQGPQL 305
Cdd:PRK09694 227 DWLGSWTTTFTFLFNspILALRQYFQQRQQDAARVLELSGLVANKKPYGGVHALLDNGYQPRQLQTLVDAL---PLQPGL 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 306 FILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSpesRPSLVLAHSArtlmDRFNES 385
Cdd:PRK09694 304 TIIEAPTGSGKTEAALAYAWRLIDQGLADSIIFALPTQATANAMLSRLEALASKLFP---SPNLILAHGN----SRFNHL 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 386 LWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMS 465
Cdd:PRK09694 377 FQSLKSRAATEQGQEEAWVQCCEWLSQSNKRVFLGQIGVCTIDQVLISVLPVKHRFIRGFGLGRSVLIVDEVHAYDAYMY 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 466 CILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEApflekdDYPWLTH---VTKSDVNSHRVATRKDVE 542
Cdd:PRK09694 457 GLLEAVLKAQAQAGGSVILLSATLPATLKQKLLDTYGGHDPVELSS------AYPLITWrgvNGAQRFDLSAHPEQLPAR 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 543 RSVSVGWLHSEQEC-----IARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGViPASSLSLFHSRFAFSDRQRIETET 617
Cdd:PRK09694 531 FTIQLEPICLADMLpdltlLQRMIAAANAGAQVCLICNLVDDAQKLYQRLKELNN-TQVDIDLFHARFTLNDRREKEQRV 609
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 618 LARFGKYCSlQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDingqlKR-DGKDErspPELLILA 696
Cdd:PRK09694 610 IENFGKNGK-RNQGRILVATQVVEQSLDLDFDWLITQLCPVDLLFQRLGRLHRHHRK-----YRpAGFEI---PVATVLL 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 697 PVWDDSPGdewfgsamrnSAFVYPDHGRIWLTQRVLREQGAIQM--PHAARLLIESVYGED------VVMPEGFARSEQE 768
Cdd:PRK09694 681 PDGEGYGR----------SGYIYGNTRVLWRTEQLLEEHNAASLffPDAYREWIESVYDEAemdeepEWVISGMDKFEDK 750
|
810
....*....|....
gi 447156693 769 QVGKYYCDRAMAKK 782
Cdd:PRK09694 751 ECEKRYKARKMLKW 764
|
|
| Cas3 |
COG1203 |
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]; ... |
162-754 |
2.90e-113 |
|
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]; CRISPR-Cas type I system-associated endonuclease/helicase Cas3 is part of the Pathway/BioSystem: CRISPR-Cas system
Pssm-ID: 440816 [Multi-domain] Cd Length: 535 Bit Score: 357.47 E-value: 2.90e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 162 HHGRPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISAtVVLADWTGSSTRFFPRVA 241
Cdd:COG1203 27 LAALLLLLLAALLLALLLALLLLAALELALLLLLLLLLLLLLLLLLLDLLLDDLAFLFLLL-LIDADWLDSANFDMARQA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 242 HPMDIKgywqktliqaqnaltvfplkakvapfNGINTLFPFIENPT----PLQQKVLDLDISQ--QGPQLFILEDVTGAG 315
Cdd:COG1203 106 LDHLLA--------------------------ERLERLLPKKSKPRtpinPLQNEALELALEAaeEEPGLFILTAPTGGG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 316 KTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTwlafyspeSRPSLVLAHSARTLmdrfneslwsgdlvgsE 395
Cdd:COG1203 160 KTEAALLFALRLAAKHGGRRIIYALPFTSIINQTYDRLRDL--------FGEDVLLHHSLADL----------------D 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 396 EPDEQTFSQGCAAWFADsNKKALLAEIGVGTLDQAMMAVM-PFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIER 474
Cdd:COG1203 216 LLEEEEEYESEARWLKL-LKELWDAPVVVTTIDQLFESLFsNRKGQERRLHNLANSVIILDEVQAYPPYMLALLLRLLEW 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 475 QARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLekddypwlthvtksdvnshrvaTRKDVERSVSVGWLH-SE 553
Cdd:COG1203 295 LKNLGGSVILMTATLPPLLREELLEAYELIPDEPEELPEY----------------------FRAFVRKRVELKEGPlSD 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 554 QECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLlaRGVIPASSLSLFHSRFAFSDRQRIETETLARFGKycslqRASQV 633
Cdd:COG1203 353 EELAELILEALHKGKSVLVIVNTVKDAQELYEAL--KEKLPDEEVYLLHSRFCPADRSEIEKEIKERLER-----GKPCI 425
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 634 IVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDingqlkrdgkdeRSPPELLILAPVWDdspgdewfgsamr 713
Cdd:COG1203 426 LVSTQVVEAGVDIDFDVVIRDLAPLDSLIQRAGRCNRHGRK------------EEEGNVYVFDPEDE------------- 480
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 447156693 714 NSAFVYPDHGrIWLTQRVLREQGAIqMPHAARLLIESVYGE 754
Cdd:COG1203 481 GGGYVYDKPL-LERTRELLREHDEI-LPEDKRELIEEYYRE 519
|
|
| cas3_core |
TIGR01587 |
CRISPR-associated helicase Cas3; This model represents the highly conserved core region of an ... |
305-734 |
2.14e-66 |
|
CRISPR-associated helicase Cas3; This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.
Pssm-ID: 273707 [Multi-domain] Cd Length: 359 Bit Score: 226.18 E-value: 2.14e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 305 LFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAfyspesrpSLVLAHSartlmdrfne 384
Cdd:TIGR01587 1 LLVIEAPTGYGKTEAALLWALHSIKSQKADRVIIALPTRATINAMYRRAKELFGS--------ELVGLHH---------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 385 SLWSGDLvgSEEPDEQTFSQgCAAWFADSNKKALLAEIGVGTLDQAMMAVMP-FKHNNLRLLGLSNKILLADEIHACDAY 463
Cdd:TIGR01587 63 SSSFSRI--KEMGDSEEFEH-LFPLYIHSNDKLFLDPITVCTIDQVLKSVFGeFGHYEFTLASIANSLLIFDEVHFYDEY 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 464 MSCILEGLIERQARGGNSVILLSATLSqqqrdKLVAAFARGTEGQQEAPFLEKDDYPWLTHvtksdvnsHRVATRKDVer 543
Cdd:TIGR01587 140 TLALILAVLEVLKDNDVPILLMSATLP-----KFLKEYAEKIGYVEFNEPLDLKEERRFEN--------HRFILIESD-- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 544 svsvgWLHSEQEcIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGviPASSLSLFHSRFAFSDRQRIETETLARFGK 623
Cdd:TIGR01587 205 -----KVGEISS-LERLLEFIKKGGSIAIIVNTVDRAQEFYQQLKEKA--PEEEIILYHSRFTEKDRAKKEAELLREMKK 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 624 ycslQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHirdingqlkrdGKDERSPPELLILAPVWDDSp 703
Cdd:TIGR01587 277 ----SNEKFVIVATQVIEASLDISADVMITELAPIDSLIQRLGRLHRY-----------GRKIGENFEVYIITIAPEGK- 340
|
410 420 430
....*....|....*....|....*....|.
gi 447156693 704 gdewfgsamrnsaFVYPDHGRIWLTQRVLRE 734
Cdd:TIGR01587 341 -------------LFPYPYELVERTIQKLEE 358
|
|
| Cas3_I |
cd09639 |
CRISPR/Cas system-associated protein Cas3; CRISPR (Clustered Regularly Interspaced Short ... |
305-734 |
5.47e-62 |
|
CRISPR/Cas system-associated protein Cas3; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I
Pssm-ID: 187770 [Multi-domain] Cd Length: 353 Bit Score: 213.83 E-value: 5.47e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 305 LFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTwlaFYSPESRPSLVLahsartlMDRFne 384
Cdd:cd09639 1 LLVIEAPTGYGKTEAALLWALHSLKSQKADRVIIALPTRATINAMYRRAKEA---FGETGLYHSSIL-------SSRI-- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 385 slwsgdlvgSEEPDEQTFSQgCAAWFADSNKKALLAEIGVGTLDQAMMAVMP-FKHNNLRLLGLSNKILLADEIHACDAY 463
Cdd:cd09639 69 ---------KEMGDSEEFEH-LFPLYIHSNDTLFLDPITVCTIDQVLKSVFGeFGHYEFTLASIANSLLIFDEVHFYDEY 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 464 MSCILEGLIERQARGGNSVILLSATLSqqqrdKLVAAFARGTEGQQEAPFLEKDDYpwlthvtksdvnsHRVATRKDVER 543
Cdd:cd09639 139 TLALILAVLEVLKDNDVPILLMSATLP-----KFLKEYAEKIGYVEENEPLDLKPN-------------ERAPFIKIESD 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 544 SVSvgwlhsEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGviPASSLSLFHSRFAFSDRQRIETETLARFGK 623
Cdd:cd09639 201 KVG------EISSLERLLEFIKKGGSVAIIVNTVDRAQEFYQQLKEKG--PEEEIMLIHSRFTEKDRAKKEAELLLEFKK 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 624 ycslqRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHirdingqlkrdgkDERSPPELLILAPVwddSP 703
Cdd:cd09639 273 -----SEKFVIVATQVIEASLDISVDVMITELAPIDSLIQRLGRLHRY-------------GEKNGEEVYIITDA---PD 331
|
410 420 430
....*....|....*....|....*....|.
gi 447156693 704 GDEwfgsamrnsaFVYPDHGRIWLTQRVLRE 734
Cdd:cd09639 332 GKG----------QKPYPYDLVERTIELLEE 352
|
|
| HD_6 |
pfam18019 |
HD domain; This HD domain is found at the N-terminus of Cas3 enzymes fused to a helicase ... |
21-237 |
5.00e-39 |
|
HD domain; This HD domain is found at the N-terminus of Cas3 enzymes fused to a helicase domain. This domain is sometimes found as a separate protein. It acts as a nuclease that cleaves ssDNA.
Pssm-ID: 436216 Cd Length: 212 Bit Score: 144.12 E-value: 5.00e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 21 WGKTRRgekDGGDDYHLLCWHSLDVAAMGYLMVKRN-CFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLY 99
Cdd:pfam18019 1 WAKSDR---EGGGGWHPLVYHLLDVAAVAGALWDHWlAPGVRDLLARLLGLDEEAARRLLAFLAALHDIGKASPAFQAKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 100 LPPELKIQEG-----ARKNYEKISHSTLGYWLWNHYLSECQELlpssslsprkLRRVIEMWMPVTTGHHGRPPDRMDELD 174
Cdd:pfam18019 78 PELAEKLRDAglpfpSSLDESRARHGLAGAALLREWLEDEAGW----------DRGVARALAAAVGGHHGRPPAEDLRLA 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447156693 175 NFLP------------EDKAAARDFLLEIKPLFPLIEIPAFwdddegieliKHLSWYISATVVLADWTGSSTRFF 237
Cdd:pfam18019 148 RPALrpaggswqearrELLEAAAAFLGAAAVLLLPPARELS----------QPAQVLLAGLVILADWIASNEDFF 212
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
282-491 |
8.16e-07 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 50.57 E-value: 8.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 282 FIENPTPLQQKVLDldISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKtwlafY 361
Cdd:smart00487 5 GFEPLRPYQKEAIE--ALLSGLRDVILAAPTGSGKTLAALLPALEALKRGKGGRVLVLVPTRELAEQWAEELKK-----L 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 362 SPESRPSLVLAHSARTLMDRFNEslwsgdlVGSEEPDeqtfsqgcaawfadsnkkallaeIGVGTLDQA--MMAVMPFKH 439
Cdd:smart00487 78 GPSLGLKVVGLYGGDSKREQLRK-------LESGKTD-----------------------ILVTTPGRLldLLENDKLSL 127
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 447156693 440 NNLRLLglsnkILlaDEIHAC-DAYMSCILEGLIERqARGGNSVILLSATLSQ 491
Cdd:smart00487 128 SNVDLV-----IL--DEAHRLlDGGFGDQLEKLLKL-LPKNVQLLLLSATPPE 172
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09694 |
PRK09694 |
CRISPR-associated helicase/endonuclease Cas3; |
16-782 |
2.06e-129 |
|
CRISPR-associated helicase/endonuclease Cas3;
Pssm-ID: 182031 [Multi-domain] Cd Length: 878 Bit Score: 410.35 E-value: 2.06e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 16 TFFDFWGKTRRgEKDGGDDYHLLCWHSLDVAAmgylmvkrncfgLADYF--------RQLGISDKEQAAQFFAWLLCW-- 85
Cdd:PRK09694 6 YYCRYWGKASK-SLTKGNDYHLLPYHCLDVAA------------VADCWwdqspvlrSQFSANEMLSKQQVRAWLLFFva 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 86 -HDIGKFARSFQ-------QLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMP 157
Cdd:PRK09694 73 lHDIGKFDIRFQykapeiwLKLNPAGPSISGPSTQMCRKYDHGAAGLLWFRQDFRSNQASDDSFFDAAPHPYEAWFPWME 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 158 VTTGHHGR------PPDRM----DELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFwdDDEGIELIKHLSWYISatvvLA 227
Cdd:PRK09694 153 AVTGHHGYilhsqdQDDSRwempASLASYAEQDKQAREEWIQALEALFLTPAGLSL--NDIPPPCSPLLAGFCS----VS 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 228 DWTGSSTRFFPRVAH--PMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLdisQQGPQL 305
Cdd:PRK09694 227 DWLGSWTTTFTFLFNspILALRQYFQQRQQDAARVLELSGLVANKKPYGGVHALLDNGYQPRQLQTLVDAL---PLQPGL 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 306 FILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSpesRPSLVLAHSArtlmDRFNES 385
Cdd:PRK09694 304 TIIEAPTGSGKTEAALAYAWRLIDQGLADSIIFALPTQATANAMLSRLEALASKLFP---SPNLILAHGN----SRFNHL 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 386 LWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMS 465
Cdd:PRK09694 377 FQSLKSRAATEQGQEEAWVQCCEWLSQSNKRVFLGQIGVCTIDQVLISVLPVKHRFIRGFGLGRSVLIVDEVHAYDAYMY 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 466 CILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEApflekdDYPWLTH---VTKSDVNSHRVATRKDVE 542
Cdd:PRK09694 457 GLLEAVLKAQAQAGGSVILLSATLPATLKQKLLDTYGGHDPVELSS------AYPLITWrgvNGAQRFDLSAHPEQLPAR 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 543 RSVSVGWLHSEQEC-----IARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGViPASSLSLFHSRFAFSDRQRIETET 617
Cdd:PRK09694 531 FTIQLEPICLADMLpdltlLQRMIAAANAGAQVCLICNLVDDAQKLYQRLKELNN-TQVDIDLFHARFTLNDRREKEQRV 609
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 618 LARFGKYCSlQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDingqlKR-DGKDErspPELLILA 696
Cdd:PRK09694 610 IENFGKNGK-RNQGRILVATQVVEQSLDLDFDWLITQLCPVDLLFQRLGRLHRHHRK-----YRpAGFEI---PVATVLL 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 697 PVWDDSPGdewfgsamrnSAFVYPDHGRIWLTQRVLREQGAIQM--PHAARLLIESVYGED------VVMPEGFARSEQE 768
Cdd:PRK09694 681 PDGEGYGR----------SGYIYGNTRVLWRTEQLLEEHNAASLffPDAYREWIESVYDEAemdeepEWVISGMDKFEDK 750
|
810
....*....|....
gi 447156693 769 QVGKYYCDRAMAKK 782
Cdd:PRK09694 751 ECEKRYKARKMLKW 764
|
|
| Cas3 |
COG1203 |
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]; ... |
162-754 |
2.90e-113 |
|
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]; CRISPR-Cas type I system-associated endonuclease/helicase Cas3 is part of the Pathway/BioSystem: CRISPR-Cas system
Pssm-ID: 440816 [Multi-domain] Cd Length: 535 Bit Score: 357.47 E-value: 2.90e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 162 HHGRPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISAtVVLADWTGSSTRFFPRVA 241
Cdd:COG1203 27 LAALLLLLLAALLLALLLALLLLAALELALLLLLLLLLLLLLLLLLLDLLLDDLAFLFLLL-LIDADWLDSANFDMARQA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 242 HPMDIKgywqktliqaqnaltvfplkakvapfNGINTLFPFIENPT----PLQQKVLDLDISQ--QGPQLFILEDVTGAG 315
Cdd:COG1203 106 LDHLLA--------------------------ERLERLLPKKSKPRtpinPLQNEALELALEAaeEEPGLFILTAPTGGG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 316 KTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTwlafyspeSRPSLVLAHSARTLmdrfneslwsgdlvgsE 395
Cdd:COG1203 160 KTEAALLFALRLAAKHGGRRIIYALPFTSIINQTYDRLRDL--------FGEDVLLHHSLADL----------------D 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 396 EPDEQTFSQGCAAWFADsNKKALLAEIGVGTLDQAMMAVM-PFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIER 474
Cdd:COG1203 216 LLEEEEEYESEARWLKL-LKELWDAPVVVTTIDQLFESLFsNRKGQERRLHNLANSVIILDEVQAYPPYMLALLLRLLEW 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 475 QARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLekddypwlthvtksdvnshrvaTRKDVERSVSVGWLH-SE 553
Cdd:COG1203 295 LKNLGGSVILMTATLPPLLREELLEAYELIPDEPEELPEY----------------------FRAFVRKRVELKEGPlSD 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 554 QECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLlaRGVIPASSLSLFHSRFAFSDRQRIETETLARFGKycslqRASQV 633
Cdd:COG1203 353 EELAELILEALHKGKSVLVIVNTVKDAQELYEAL--KEKLPDEEVYLLHSRFCPADRSEIEKEIKERLER-----GKPCI 425
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 634 IVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDingqlkrdgkdeRSPPELLILAPVWDdspgdewfgsamr 713
Cdd:COG1203 426 LVSTQVVEAGVDIDFDVVIRDLAPLDSLIQRAGRCNRHGRK------------EEEGNVYVFDPEDE------------- 480
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 447156693 714 NSAFVYPDHGrIWLTQRVLREQGAIqMPHAARLLIESVYGE 754
Cdd:COG1203 481 GGGYVYDKPL-LERTRELLREHDEI-LPEDKRELIEEYYRE 519
|
|
| cas3_core |
TIGR01587 |
CRISPR-associated helicase Cas3; This model represents the highly conserved core region of an ... |
305-734 |
2.14e-66 |
|
CRISPR-associated helicase Cas3; This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.
Pssm-ID: 273707 [Multi-domain] Cd Length: 359 Bit Score: 226.18 E-value: 2.14e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 305 LFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAfyspesrpSLVLAHSartlmdrfne 384
Cdd:TIGR01587 1 LLVIEAPTGYGKTEAALLWALHSIKSQKADRVIIALPTRATINAMYRRAKELFGS--------ELVGLHH---------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 385 SLWSGDLvgSEEPDEQTFSQgCAAWFADSNKKALLAEIGVGTLDQAMMAVMP-FKHNNLRLLGLSNKILLADEIHACDAY 463
Cdd:TIGR01587 63 SSSFSRI--KEMGDSEEFEH-LFPLYIHSNDKLFLDPITVCTIDQVLKSVFGeFGHYEFTLASIANSLLIFDEVHFYDEY 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 464 MSCILEGLIERQARGGNSVILLSATLSqqqrdKLVAAFARGTEGQQEAPFLEKDDYPWLTHvtksdvnsHRVATRKDVer 543
Cdd:TIGR01587 140 TLALILAVLEVLKDNDVPILLMSATLP-----KFLKEYAEKIGYVEFNEPLDLKEERRFEN--------HRFILIESD-- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 544 svsvgWLHSEQEcIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGviPASSLSLFHSRFAFSDRQRIETETLARFGK 623
Cdd:TIGR01587 205 -----KVGEISS-LERLLEFIKKGGSIAIIVNTVDRAQEFYQQLKEKA--PEEEIILYHSRFTEKDRAKKEAELLREMKK 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 624 ycslQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHirdingqlkrdGKDERSPPELLILAPVWDDSp 703
Cdd:TIGR01587 277 ----SNEKFVIVATQVIEASLDISADVMITELAPIDSLIQRLGRLHRY-----------GRKIGENFEVYIITIAPEGK- 340
|
410 420 430
....*....|....*....|....*....|.
gi 447156693 704 gdewfgsamrnsaFVYPDHGRIWLTQRVLRE 734
Cdd:TIGR01587 341 -------------LFPYPYELVERTIQKLEE 358
|
|
| Cas3_I |
cd09639 |
CRISPR/Cas system-associated protein Cas3; CRISPR (Clustered Regularly Interspaced Short ... |
305-734 |
5.47e-62 |
|
CRISPR/Cas system-associated protein Cas3; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I
Pssm-ID: 187770 [Multi-domain] Cd Length: 353 Bit Score: 213.83 E-value: 5.47e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 305 LFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTwlaFYSPESRPSLVLahsartlMDRFne 384
Cdd:cd09639 1 LLVIEAPTGYGKTEAALLWALHSLKSQKADRVIIALPTRATINAMYRRAKEA---FGETGLYHSSIL-------SSRI-- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 385 slwsgdlvgSEEPDEQTFSQgCAAWFADSNKKALLAEIGVGTLDQAMMAVMP-FKHNNLRLLGLSNKILLADEIHACDAY 463
Cdd:cd09639 69 ---------KEMGDSEEFEH-LFPLYIHSNDTLFLDPITVCTIDQVLKSVFGeFGHYEFTLASIANSLLIFDEVHFYDEY 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 464 MSCILEGLIERQARGGNSVILLSATLSqqqrdKLVAAFARGTEGQQEAPFLEKDDYpwlthvtksdvnsHRVATRKDVER 543
Cdd:cd09639 139 TLALILAVLEVLKDNDVPILLMSATLP-----KFLKEYAEKIGYVEENEPLDLKPN-------------ERAPFIKIESD 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 544 SVSvgwlhsEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGviPASSLSLFHSRFAFSDRQRIETETLARFGK 623
Cdd:cd09639 201 KVG------EISSLERLLEFIKKGGSVAIIVNTVDRAQEFYQQLKEKG--PEEEIMLIHSRFTEKDRAKKEAELLLEFKK 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 624 ycslqRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHirdingqlkrdgkDERSPPELLILAPVwddSP 703
Cdd:cd09639 273 -----SEKFVIVATQVIEASLDISVDVMITELAPIDSLIQRLGRLHRY-------------GEKNGEEVYIITDA---PD 331
|
410 420 430
....*....|....*....|....*....|.
gi 447156693 704 GDEwfgsamrnsaFVYPDHGRIWLTQRVLRE 734
Cdd:cd09639 332 GKG----------QKPYPYDLVERTIELLEE 352
|
|
| DEXHc_cas3 |
cd17930 |
DEXH/Q-box helicase domain of Cas3; CRISPR-associated (Cas) 3 is a nuclease-helicase ... |
303-503 |
1.68e-55 |
|
DEXH/Q-box helicase domain of Cas3; CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350688 [Multi-domain] Cd Length: 186 Bit Score: 189.81 E-value: 1.68e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 303 PQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKtWLAFYSPEsrPSLVLAHSARTLMDRF 382
Cdd:cd17930 1 PGLVILEAPTGSGKTEAALLWALKLAARGGKRRIIYALPTRATINQMYERIRE-ILGRLDDE--DKVLLLHSKAALELLE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 383 NESLWSGDLVgseepdeqtfsqgCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDA 462
Cdd:cd17930 78 SDEEPDDDPV-------------EAVDWALLLKRSWLAPIVVTTIDQLLESLLKYKHFERRLHGLANSVVVLDEVQAYDP 144
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 447156693 463 -YMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFAR 503
Cdd:cd17930 145 eYMALLLKALLELLGELGGPVVLMTATLPALLRDELLEALLK 186
|
|
| HD_6 |
pfam18019 |
HD domain; This HD domain is found at the N-terminus of Cas3 enzymes fused to a helicase ... |
21-237 |
5.00e-39 |
|
HD domain; This HD domain is found at the N-terminus of Cas3 enzymes fused to a helicase domain. This domain is sometimes found as a separate protein. It acts as a nuclease that cleaves ssDNA.
Pssm-ID: 436216 Cd Length: 212 Bit Score: 144.12 E-value: 5.00e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 21 WGKTRRgekDGGDDYHLLCWHSLDVAAMGYLMVKRN-CFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLY 99
Cdd:pfam18019 1 WAKSDR---EGGGGWHPLVYHLLDVAAVAGALWDHWlAPGVRDLLARLLGLDEEAARRLLAFLAALHDIGKASPAFQAKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 100 LPPELKIQEG-----ARKNYEKISHSTLGYWLWNHYLSECQELlpssslsprkLRRVIEMWMPVTTGHHGRPPDRMDELD 174
Cdd:pfam18019 78 PELAEKLRDAglpfpSSLDESRARHGLAGAALLREWLEDEAGW----------DRGVARALAAAVGGHHGRPPAEDLRLA 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447156693 175 NFLP------------EDKAAARDFLLEIKPLFPLIEIPAFwdddegieliKHLSWYISATVVLADWTGSSTRFF 237
Cdd:pfam18019 148 RPALrpaggswqearrELLEAAAAFLGAAAVLLLPPARELS----------QPAQVLLAGLVILADWIASNEDFF 212
|
|
| Cas3''_I |
cd09641 |
CRISPR/Cas system-associated protein Cas3''; CRISPR (Clustered Regularly Interspaced Short ... |
30-238 |
3.37e-26 |
|
CRISPR/Cas system-associated protein Cas3''; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; HD-like nuclease, specifically digesting double-stranded oligonucleotides and preferably cleaving at G:C pairs; signature gene for Type I
Pssm-ID: 193608 [Multi-domain] Cd Length: 200 Bit Score: 106.97 E-value: 3.37e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 30 DGGDDYHLLCWHSLDVAAMGYLMVKRncfgladYFRQLGISDKEQAaQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEG 109
Cdd:cd09641 1 AKSGPWQPLLEHLLDVAAWDAELAEE-------FARKLGLELGLSR-ELLALAGLLHDLGKATPAFQKYLRGGKEALREG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 110 ARKnyeKISHSTLGYWLWNHYLSECQEllpssslsprkLRRVIEMWMPVTTGHHGRPPD------------------RMD 171
Cdd:cd09641 73 KRK---EVRHSLLGALLLYELLKELGL-----------DEELALLLAYAIAGHHGGLPDvlllldeddesalkerleELD 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447156693 172 ELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIelikhLSWYISATVVLADWTGSSTRFFP 238
Cdd:cd09641 139 EEKLLLELWEEELEELLDELLKELLLLLLPELLSFELYL-----LLRLLFSLLVDADWLASAEFFFP 200
|
|
| cas3_HD |
TIGR01596 |
CRISPR-associated endonuclease Cas3-HD; CRISPR/Cas systems are widespread, mobile systems for ... |
38-232 |
4.75e-26 |
|
CRISPR-associated endonuclease Cas3-HD; CRISPR/Cas systems are widespread, mobile systems for host defense against invasive elements such as phage. In these systems, Cas3 designates one of the core proteins shared widely by multiple types of CRISPR/Cas system. This model represents an HD-like endonuclease that occurs either separately or as the N-terminal region of Cas3, the helicase-containing CRISPR-associated protein.
Pssm-ID: 273711 [Multi-domain] Cd Length: 176 Bit Score: 105.75 E-value: 4.75e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 38 LCWHSLDVAAMGYLMVKRncfgLADYFRQLGIsdkeQAAQFFAWLLCWHDIGKFARSFQQLYLPPElkiqegARKNYEKI 117
Cdd:TIGR01596 1 LKEHLLDVAAVAEALPAL----RPRLAEKLGL----ELRELLKLAGLLHDLGKASPAFQKKLRKAE------ERGDRGEV 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 118 SHSTLGYWLWNHYLSECQELlpssslsprklRRVIEMWMPVTTGHHGRPPD------RMDELDNFLPEDKAAARDFLLEI 191
Cdd:TIGR01596 67 RHSTLSAALLYDLLEELGLE-----------EELALLLALAIAGHHGGLIDdddleeLLELLERELEEALGELLEELEEL 135
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 447156693 192 KPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGS 232
Cdd:TIGR01596 136 LDEVLKALPLRLLLDKEEPIELYLLARLLFGLLVDADWLAS 176
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
306-488 |
6.86e-10 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 58.18 E-value: 6.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 306 FILEDVTGAGKTEAALILAHRLIAAGKAQGLFFgLPTMATANAMYDRlvktwlafyspesrpslvlahsartLMDRFNES 385
Cdd:cd00046 4 VLITAPTGSGKTLAALLAALLLLLKKGKKVLVL-VPTKALALQTAER-------------------------LRELFGPG 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 386 LWSGDLVGSEEPDEQTfsqgcaawfadsNKKALLAEIGVGTLDQAMMAVMPfkhnNLRLLGLSNKILLADEIHACDAYMS 465
Cdd:cd00046 58 IRVAVLVGGSSAEERE------------KNKLGDADIIIATPDMLLNLLLR----EDRLFLKDLKLIIVDEAHALLIDSR 121
|
170 180
....*....|....*....|....*
gi 447156693 466 CILEGL--IERQARGGNSVILLSAT 488
Cdd:cd00046 122 GALILDlaVRKAGLKNAQVILLSAT 146
|
|
| Cas3_I |
cd09696 |
CRISPR/Cas system-associated protein Cas3; Distinct Cas3 family with HD domain fused to ... |
407-670 |
1.91e-07 |
|
CRISPR/Cas system-associated protein Cas3; Distinct Cas3 family with HD domain fused to C-termus of Helicase domain; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DNA helicase Cas3; This protein includes both DEAH and HD motifs; signature gene for Type I
Pssm-ID: 187827 [Multi-domain] Cd Length: 843 Bit Score: 55.03 E-value: 1.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 407 AAWFADSNKKALLaeigVGTLDQAMMAVM------PFKHNNLR--LLGlSNKILLADEIHACDAYMScileglierqarg 478
Cdd:cd09696 126 DEWMLDPHRPAVI----VGTVDMIGSRLLfsgygcGFKSRPLHagFLG-QDALIVHDEAHLEPAFQE------------- 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 479 gnsviLLSATLSQQQRDK--------LVAAFARgTEGQQEAPFLEKDDYpwlthvtKSDVNSHRVATRKdverSVSVGWL 550
Cdd:cd09696 188 -----LLKQIMNEQQRPPdflplrvvELTATSR-TDGPDRTTLLSAEDY-------KHPVLKKRLAAKK----IVKLVPP 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 551 HSEQECIARIESAV----SQGKCIAWIRNSVDDAIKVHRQLlaRGVIPasslSLFHSRFAFSDRQRI-ETETLARF---- 621
Cdd:cd09696 251 SDEKFLSTMVKELNllmkDSGGAILVFCRTVKHVRKVFAKL--PKEKF----ELLTGTLRGAERDDLvKKEIFNRFlpqm 324
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 447156693 622 --GKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQR 670
Cdd:cd09696 325 lsGSRARPQQGTVYLVCTSAGEVGVNISADHLVCDLAPFESMQQRFGRVNR 375
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
282-491 |
8.16e-07 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 50.57 E-value: 8.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 282 FIENPTPLQQKVLDldISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKtwlafY 361
Cdd:smart00487 5 GFEPLRPYQKEAIE--ALLSGLRDVILAAPTGSGKTLAALLPALEALKRGKGGRVLVLVPTRELAEQWAEELKK-----L 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447156693 362 SPESRPSLVLAHSARTLMDRFNEslwsgdlVGSEEPDeqtfsqgcaawfadsnkkallaeIGVGTLDQA--MMAVMPFKH 439
Cdd:smart00487 78 GPSLGLKVVGLYGGDSKREQLRK-------LESGKTD-----------------------ILVTTPGRLldLLENDKLSL 127
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 447156693 440 NNLRLLglsnkILlaDEIHAC-DAYMSCILEGLIERqARGGNSVILLSATLSQ 491
Cdd:smart00487 128 SNVDLV-----IL--DEAHRLlDGGFGDQLEKLLKL-LPKNVQLLLLSATPPE 172
|
|
| HELICc |
smart00490 |
helicase superfamily c-terminal domain; |
601-670 |
3.06e-03 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 37.58 E-value: 3.06e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 447156693 601 FHSRFafSDRQRIETETLARFGKycslqraSQVIVCTQVIEQSVDI-DLDEMISDLAP--VDLLIQRAGRLQR 670
Cdd:smart00490 17 LHGGL--SQEEREEILDKFNNGK-------IKVLVATDVAERGLDLpGVDLVIIYDLPwsPASYIQRIGRAGR 80
|
|
| |
