|
Name |
Accession |
Description |
Interval |
E-value |
| Chorismate_bind |
pfam00425 |
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ... |
117-376 |
6.70e-107 |
|
chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.
Pssm-ID: 425674 [Multi-domain] Cd Length: 255 Bit Score: 314.49 E-value: 6.70e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 117 EVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPIST--LYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGqfnn 194
Cdd:pfam00425 1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLPLAGDIDPlaLYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSVD---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 195 vDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSM 274
Cdd:pfam00425 77 -GGRIITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVST 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 275 VSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPteDDKMIFNIPIRTIEYKYGQAIY 354
Cdd:pfam00425 156 ISGRLKPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDP--DGDADFAVAIRTALVDNGRARL 233
|
250 260
....*....|....*....|..
gi 447140530 355 GVGAGITIDSKPKDEVNEFYAK 376
Cdd:pfam00425 234 YAGAGIVADSDPEAEWEETEAK 255
|
|
| pabB |
TIGR00553 |
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, ... |
58-380 |
4.70e-103 |
|
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, aminodeoxychorismate synthase, component I (PabB), were designated para-aminobenzoate synthase component I until it was recognized that PabC, a lyase, completes the pathway of PABA synthesis. This family is closely related to anthranilate synthase component I (trpE), and both act on chorismate. The clade of PabB enzymes represented by this model includes sequences from Gram-positive and alpha and gamma Proteobacteria as well as Chlorobium, Nostoc, Fusobacterium and Arabidopsis. A closely related clade of fungal PabB enzymes is identified by TIGR01823, while another bacterial clade of potential PabB enzymes is more closely related to TrpE (TIGR01824). [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid]
Pssm-ID: 273133 Cd Length: 328 Bit Score: 307.38 E-value: 4.70e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 58 YLSYEAAKYFNHVMCSHSLAKDDI---YAVAYSFEKAE-SINSTYEHQTSyVSKHHFSFVESSEVMMTN------IKRVQ 127
Cdd:TIGR00553 4 YLSYEAGPDAAFEPYDAALLADHRrtpLLRFLVFERVEaQPRAAVEAEDD-APADRQAPTSDIQSEMTRaeygeaIDQLQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 128 QAIVEGETYQVNYTARLTDNIYYPISTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGqfnnvDNVIISKPMKGT 207
Cdd:TIGR00553 83 DYIRAGDCYQANLTQQFHATWDGDPLAAFRKLRRRQPAPFSAFLDLGDGAILSLSPELFFSID-----GSEIETRPIKGT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 208 MPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQ 287
Cdd:TIGR00553 158 LPRGADPQEDRAQASALAESAKDRAENLMIVDLLRNDLGRIAEVGSVKVPELFVVETYPTVHQLVSTITARLREDLTLSD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 288 ILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDdkMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPK 367
Cdd:TIGR00553 238 LFRALFPGGSITGAPKVRAMEIIDELEPQPRGVYCGAIGYLSPEGD--MDFNVAIRTLTLDGGRAVYGVGGGIVADSDPE 315
|
330
....*....|...
gi 447140530 368 DEVNEFYAKTKIL 380
Cdd:TIGR00553 316 AEYRECLLKAAPL 328
|
|
| PRK07508 |
PRK07508 |
aminodeoxychorismate synthase component I; |
31-381 |
2.75e-89 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236035 [Multi-domain] Cd Length: 378 Bit Score: 273.81 E-value: 2.75e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 31 VATKLADVGEVIHFAQAQQRQGRYVSLYLSYEAAKYFNHVMCSHSLAKDDIYAVAYSFEKAESINSTYEHQTSYVSKHHF 110
Cdd:PRK07508 24 RARTPDEFAPALAAMERARAAGKWLAGYLSYEAGYLLEPKLAPLMPEGRETPLLCFGVFDAPSPEAPAPARPSENAARLR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 111 SFVE--SSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPISTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQ 188
Cdd:PRK07508 104 DPVArwDFADYAQRFERLHRHIRAGDCYQANLTFPLDARWGGDPLALFWALAARQPVGYGALVDLGGPVILSRSPELFFR 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 189 KgqfnNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTV 268
Cdd:PRK07508 184 V----DGEGWIETHPMKGTAPRGATPAEDARLRAALLNDEKNQAENRMIVDLLRNDISRISEVGSLDVPELFDIETYPTV 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 269 FQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPteDDKMIFNIPIRTIE-Y 347
Cdd:PRK07508 260 HQMVSRVRARLLPGLGLADIFAALFPCGSITGAPKIRAMEILRELEPGPRDLYCGAIGWIAP--DGRMRFNVAIRTLSlF 337
|
330 340 350
....*....|....*....|....*....|....
gi 447140530 348 KYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILE 381
Cdd:PRK07508 338 PGGRAVFNVGGGIVFDSTAEAEYEECLLKARFAV 371
|
|
| TrpE |
COG0147 |
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ... |
58-372 |
1.08e-88 |
|
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439917 [Multi-domain] Cd Length: 416 Bit Score: 273.52 E-value: 1.08e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 58 YLSYEAAKYFNHVmcsHSLAKDD---------IYAVAYSFEKaesinstYEHQTSYVSKHHFsfvessevmMTNIKRVQQ 128
Cdd:COG0147 105 YFGYDLVRYFERL---PDLAPDDlglpdaalgLYDRLLVFDH-------LKGTRSNFTREEY---------LAAVERAKE 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 129 AIVEGETYQVNYTARLTdnIYYPIS--TLYERLTQFSNGNYTALLQTDEIQVASISPELFFQkgqfnnV-DNVIISKPMK 205
Cdd:COG0147 166 YIRAGDIFQVVLSQRFS--APFEGDplALYRALRRINPSPYMFYLRFGDFAIVGSSPERLVR------VeDGRVETRPIA 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 206 GTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDL 285
Cdd:COG0147 238 GTRPRGATPEEDAALAEELLADEKERAEHLMLVDLARNDLGRVCEPGSVKVPELMVVERYSHVMHLVSTVTGRLRPGLDA 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 286 TQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLlpTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSK 365
Cdd:COG0147 318 LDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYL--SFDGNMDLAIAIRTAVVKDGRAYVQAGAGIVADSD 395
|
....*..
gi 447140530 366 PKDEVNE 372
Cdd:COG0147 396 PEAEYQE 402
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Chorismate_bind |
pfam00425 |
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ... |
117-376 |
6.70e-107 |
|
chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.
Pssm-ID: 425674 [Multi-domain] Cd Length: 255 Bit Score: 314.49 E-value: 6.70e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 117 EVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPIST--LYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGqfnn 194
Cdd:pfam00425 1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLPLAGDIDPlaLYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSVD---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 195 vDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSM 274
Cdd:pfam00425 77 -GGRIITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVST 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 275 VSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPteDDKMIFNIPIRTIEYKYGQAIY 354
Cdd:pfam00425 156 ISGRLKPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDP--DGDADFAVAIRTALVDNGRARL 233
|
250 260
....*....|....*....|..
gi 447140530 355 GVGAGITIDSKPKDEVNEFYAK 376
Cdd:pfam00425 234 YAGAGIVADSDPEAEWEETEAK 255
|
|
| pabB |
TIGR00553 |
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, ... |
58-380 |
4.70e-103 |
|
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, aminodeoxychorismate synthase, component I (PabB), were designated para-aminobenzoate synthase component I until it was recognized that PabC, a lyase, completes the pathway of PABA synthesis. This family is closely related to anthranilate synthase component I (trpE), and both act on chorismate. The clade of PabB enzymes represented by this model includes sequences from Gram-positive and alpha and gamma Proteobacteria as well as Chlorobium, Nostoc, Fusobacterium and Arabidopsis. A closely related clade of fungal PabB enzymes is identified by TIGR01823, while another bacterial clade of potential PabB enzymes is more closely related to TrpE (TIGR01824). [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid]
Pssm-ID: 273133 Cd Length: 328 Bit Score: 307.38 E-value: 4.70e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 58 YLSYEAAKYFNHVMCSHSLAKDDI---YAVAYSFEKAE-SINSTYEHQTSyVSKHHFSFVESSEVMMTN------IKRVQ 127
Cdd:TIGR00553 4 YLSYEAGPDAAFEPYDAALLADHRrtpLLRFLVFERVEaQPRAAVEAEDD-APADRQAPTSDIQSEMTRaeygeaIDQLQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 128 QAIVEGETYQVNYTARLTDNIYYPISTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGqfnnvDNVIISKPMKGT 207
Cdd:TIGR00553 83 DYIRAGDCYQANLTQQFHATWDGDPLAAFRKLRRRQPAPFSAFLDLGDGAILSLSPELFFSID-----GSEIETRPIKGT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 208 MPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQ 287
Cdd:TIGR00553 158 LPRGADPQEDRAQASALAESAKDRAENLMIVDLLRNDLGRIAEVGSVKVPELFVVETYPTVHQLVSTITARLREDLTLSD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 288 ILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDdkMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPK 367
Cdd:TIGR00553 238 LFRALFPGGSITGAPKVRAMEIIDELEPQPRGVYCGAIGYLSPEGD--MDFNVAIRTLTLDGGRAVYGVGGGIVADSDPE 315
|
330
....*....|...
gi 447140530 368 DEVNEFYAKTKIL 380
Cdd:TIGR00553 316 AEYRECLLKAAPL 328
|
|
| PRK07508 |
PRK07508 |
aminodeoxychorismate synthase component I; |
31-381 |
2.75e-89 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236035 [Multi-domain] Cd Length: 378 Bit Score: 273.81 E-value: 2.75e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 31 VATKLADVGEVIHFAQAQQRQGRYVSLYLSYEAAKYFNHVMCSHSLAKDDIYAVAYSFEKAESINSTYEHQTSYVSKHHF 110
Cdd:PRK07508 24 RARTPDEFAPALAAMERARAAGKWLAGYLSYEAGYLLEPKLAPLMPEGRETPLLCFGVFDAPSPEAPAPARPSENAARLR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 111 SFVE--SSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPISTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQ 188
Cdd:PRK07508 104 DPVArwDFADYAQRFERLHRHIRAGDCYQANLTFPLDARWGGDPLALFWALAARQPVGYGALVDLGGPVILSRSPELFFR 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 189 KgqfnNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTV 268
Cdd:PRK07508 184 V----DGEGWIETHPMKGTAPRGATPAEDARLRAALLNDEKNQAENRMIVDLLRNDISRISEVGSLDVPELFDIETYPTV 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 269 FQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPteDDKMIFNIPIRTIE-Y 347
Cdd:PRK07508 260 HQMVSRVRARLLPGLGLADIFAALFPCGSITGAPKIRAMEILRELEPGPRDLYCGAIGWIAP--DGRMRFNVAIRTLSlF 337
|
330 340 350
....*....|....*....|....*....|....
gi 447140530 348 KYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILE 381
Cdd:PRK07508 338 PGGRAVFNVGGGIVFDSTAEAEYEECLLKARFAV 371
|
|
| TrpE |
COG0147 |
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ... |
58-372 |
1.08e-88 |
|
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439917 [Multi-domain] Cd Length: 416 Bit Score: 273.52 E-value: 1.08e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 58 YLSYEAAKYFNHVmcsHSLAKDD---------IYAVAYSFEKaesinstYEHQTSYVSKHHFsfvessevmMTNIKRVQQ 128
Cdd:COG0147 105 YFGYDLVRYFERL---PDLAPDDlglpdaalgLYDRLLVFDH-------LKGTRSNFTREEY---------LAAVERAKE 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 129 AIVEGETYQVNYTARLTdnIYYPIS--TLYERLTQFSNGNYTALLQTDEIQVASISPELFFQkgqfnnV-DNVIISKPMK 205
Cdd:COG0147 166 YIRAGDIFQVVLSQRFS--APFEGDplALYRALRRINPSPYMFYLRFGDFAIVGSSPERLVR------VeDGRVETRPIA 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 206 GTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDL 285
Cdd:COG0147 238 GTRPRGATPEEDAALAEELLADEKERAEHLMLVDLARNDLGRVCEPGSVKVPELMVVERYSHVMHLVSTVTGRLRPGLDA 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 286 TQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLlpTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSK 365
Cdd:COG0147 318 LDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYL--SFDGNMDLAIAIRTAVVKDGRAYVQAGAGIVADSD 395
|
....*..
gi 447140530 366 PKDEVNE 372
Cdd:COG0147 396 PEAEYQE 402
|
|
| PabB-clade2 |
TIGR01824 |
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely ... |
121-380 |
1.41e-72 |
|
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely related to TrpE (anthranilate synthase, TIGR00564/TIGR01820/TIGR00565) than to the better characterized group of PabB enzymes (TIGR00553/TIGR01823). This clade includes one characterized enzyme from Lactococcus and the conserved function across the clade is supported by these pieces of evidence: 1) all genomes with a member in this clade also have a separate TrpE gene, 2) none of these genomes contain an aparrent PabB from any of the other PabB clades, 3) none of these sequences are found in a region of the genome in association with other Trp biosynthesis genes, 4) all of these genomes aparrently contain most if not all of the steps of the folate biosynthetic pathway (for which PABA is a precursor). Many of the sequences hit by this model are annotated as TrpE enzymes, however, we believe that all members of this clade are, in fact, PabB. The sequences from Bacillus halodurans and subtilus which score below the trusted cutoff for this model are also likely to be PabB enzymes, but are too closely related to TrpE to be separated at this time.
Pssm-ID: 130883 Cd Length: 355 Bit Score: 230.43 E-value: 1.41e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 121 TNIKRVQQAIVEGETYQVNYTARLTDNIYYPIS--TLYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGqfnnvDNV 198
Cdd:TIGR01824 101 TGVRRIKDYIRAGDVFQANLSRRLTAPIAADVDplQLFLALRAPNPAPYAIYLEEPGVDVASASPELFLARE-----GRV 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 199 IISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGT 278
Cdd:TIGR01824 176 VQTRPIAGTRPRGATLAEDGALAAELLQHDKDRAEHVMIVDLERNDLGRVCATGTVRVPELCAVESYSHVHHLVSRVTGR 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 279 LKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPteDDKMIFNIPIRTIEYKYGQAIYGVGA 358
Cdd:TIGR01824 256 LREGAGLADLIRALFPGGSITGAPKVRAMEIIDELEPQPRGPYTGSVGWIDA--DGNADLNILIRTLEGGGAQLHFRTGA 333
|
250 260
....*....|....*....|..
gi 447140530 359 GITIDSKPKDEVNEFYAKTKIL 380
Cdd:TIGR01824 334 GIVADSDPAGEWDETEAKARAL 355
|
|
| PRK09070 |
PRK09070 |
aminodeoxychorismate synthase component I; |
122-378 |
2.28e-57 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236371 [Multi-domain] Cd Length: 447 Bit Score: 193.38 E-value: 2.28e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 122 NIKRVQQAIVEGETYQVN----YTARLTDNIYYPisTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGqfnnvDN 197
Cdd:PRK09070 188 GVERVLDYIRAGDVFQVNlsraWQAQFANAVDPA--ALYARLRAANPAPFSGLFVAAGRAIVSSSPERLVSVQ-----GG 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 198 VIISKPMKGTMPRGKtEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSG 277
Cdd:PRK09070 261 VVQTRPIAGTRPRFA-GDDDAALIRELVGHPKERAEHVMLIDLERNDLGRICAPGSVEVDELMTVESYAHVHHIVSNVRG 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 278 TLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLlpTEDDKMIFNIPIRTIEYKYGQAIYGVG 357
Cdd:PRK09070 340 RLRDGVTPGEVIRAVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYL--NRDGDMDLNILIRTAEVQGNQVRFRTG 417
|
250 260
....*....|....*....|.
gi 447140530 358 AGITIDSKPKDEVNEFYAKTK 378
Cdd:PRK09070 418 AGIVVDSDPERELDETRAKAR 438
|
|
| PRK05877 |
PRK05877 |
aminodeoxychorismate synthase component I; Provisional |
123-372 |
1.50e-55 |
|
aminodeoxychorismate synthase component I; Provisional
Pssm-ID: 235634 [Multi-domain] Cd Length: 405 Bit Score: 187.60 E-value: 1.50e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 123 IKRVQQAIVEGETYQVNYTARLTDNIYYPISTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQKgqfnnVDNVIISK 202
Cdd:PRK05877 148 VLACLEAIAAGEVYQACVCTQFTGTVTGSPLDFFADGVARTAPARAAYLAGDWGAVASLSPELFLRR-----RGSVVTSS 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 203 PMKGTMPRGKTEAEdqqyyktLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTN 282
Cdd:PRK05877 223 PIKGTLPLDADPSA-------LRASAKDVAENIMIVDLVRNDLGRVARTGTVTVPELLVVRPAPGVWHLVSTVSAQVPDE 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 283 TDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDdkMIFNIPIRTIEYKY-GQAIYGVGAGIT 361
Cdd:PRK05877 296 LPMSDLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGTVGLASPVAG--CELNVAIRTVEFDAdGNAVLGVGGGIT 373
|
250
....*....|.
gi 447140530 362 IDSKPKDEVNE 372
Cdd:PRK05877 374 ADSDPDAEWQE 384
|
|
| pabB |
PRK15465 |
aminodeoxychorismate synthase component 1; |
124-383 |
2.12e-52 |
|
aminodeoxychorismate synthase component 1;
Pssm-ID: 185362 [Multi-domain] Cd Length: 453 Bit Score: 180.50 E-value: 2.12e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 124 KRVQQAIVEGETYQVNYTARLTDNIYYPISTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQkgqfnnVDNV-IISK 202
Cdd:PRK15465 198 RQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFIL------CDNSeIQTR 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 203 PMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTN 282
Cdd:PRK15465 272 PIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITARLPEQ 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 283 TDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLlpTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITI 362
Cdd:PRK15465 352 LHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYL--SFCGNMDTSITIRTLTAINGQIYCSAGGGIVA 429
|
250 260
....*....|....*....|..
gi 447140530 363 DSKPKDEVNEFYAK-TKILEML 383
Cdd:PRK15465 430 DSQEEAEYQETFDKvNRILRQL 451
|
|
| PLN02889 |
PLN02889 |
oxo-acid-lyase/anthranilate synthase |
102-378 |
1.29e-50 |
|
oxo-acid-lyase/anthranilate synthase
Pssm-ID: 215481 [Multi-domain] Cd Length: 918 Bit Score: 181.97 E-value: 1.29e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 102 TSYVSKHHFSFVESSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPIST-LYERLTQFSNGNYTALLQ--TDEIQV 178
Cdd:PLN02889 629 TFSPSKAGFLADKSREQYIKDVQKCLKYIKDGESYELCLTTQMRKRIGEIDSLgLYLHLREKNPAPYAAWLNfsNENLCI 708
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 179 ASISPELFFQKGQfnnvDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYK 258
Cdd:PLN02889 709 CSSSPERFLKLDR----NGMLEAKPIKGTIARGSTPEEDEQLKLQLQYSEKDQAENLMIVDLLRNDLGRVCEPGSVHVPN 784
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 259 LFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLlpTEDDKMIF 338
Cdd:PLN02889 785 LMDVESYTTVHTMVSTIRGKKRSNMSPVDCVRAAFPGGSMTGAPKLRSMELLDSLESSSRGIYSGSIGFF--SYNQTFDL 862
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 447140530 339 NIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAKTK 378
Cdd:PLN02889 863 NIVIRTVVIHEGEASIGAGGAIVALSNPEDEYEEMILKTR 902
|
|
| PRK05940 |
PRK05940 |
anthranilate synthase component I; |
91-378 |
1.02e-48 |
|
anthranilate synthase component I;
Pssm-ID: 235651 [Multi-domain] Cd Length: 463 Bit Score: 171.07 E-value: 1.02e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 91 AESINSTYEHQTSYVSKHHFSFVESSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPISTLYERLTQFSNGNYTAL 170
Cdd:PRK05940 164 EQPTPEPDLPLDLRTPPSSLIFYTTQQEYEAAVRQAKKYIQAGDIFQANLSLRFQTTTSADSWQIYRRLQQINPSPFASY 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 171 LQTDEIQVASISPELFFQKGqfnnvDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQ 250
Cdd:PRK05940 244 WRTPWGDVVSCSPERLVQLQ-----GNQAQTRPIAGTRPRGKTPAEDQQLAEELLSNIKERAEHIMLVDLERNDLGRVCQ 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 251 SGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLP 330
Cdd:PRK05940 319 WGSVEVDELLTIERYSHVIHLVSNVVGTLQPNRDAIDLIRALFPGGTITGCPKVRCMEIIEELEPVRRNLFYGSCGYLDQ 398
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 447140530 331 TEDdkMIFNIPIRTIEY----KYGQAIYG-VGAGITIDSKPKDEVNEFYAKTK 378
Cdd:PRK05940 399 RGN--LDLNILIRTLLYtplsRGLSTIWGqVGAGIVADSDPEKEWLESLQKAK 449
|
|
| PRK13572 |
PRK13572 |
anthranilate synthase component I; Provisional |
115-383 |
3.58e-42 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 237432 [Multi-domain] Cd Length: 435 Bit Score: 152.97 E-value: 3.58e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 115 SSEVMMTNIKRVQQAIVEGETYQV----NYTARlTDniYYPIsTLYERLTQFSNGNYTALLQTDEIQVASiSPELFfqkG 190
Cdd:PRK13572 171 DREEFVEMVEKAKEYIYSGDVFQVvlsrEYRLK-TD--LSPF-QLYRNLREINPSPYMFLLEFDKDVVGA-SPETM---A 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 191 QFNNvdNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQ 270
Cdd:PRK13572 243 SVEN--NILKINPIAGTAPRGKTEEEDKKLAEALLSDEKERAEHVMLVDLARNDVRKVSKSGSVRLERFFDVVKYSHVQH 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 271 MTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDDKMIfnIPIRTIEYKyG 350
Cdd:PRK13572 321 IESEVVGELKEDSTMFDAIEAAFPAGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLA--IAIRMAEID-K 397
|
250 260 270
....*....|....*....|....*....|....
gi 447140530 351 QAIYGVGAGITIDSKPKdevNEFY-AKTKILEML 383
Cdd:PRK13572 398 VCRVRAGAGIVADSVPE---KEFYeTERKMAAVL 428
|
|
| PRK13574 |
PRK13574 |
anthranilate synthase component I; Provisional |
155-382 |
1.85e-38 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184155 [Multi-domain] Cd Length: 420 Bit Score: 142.65 E-value: 1.85e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 155 LYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGqfnnvDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAEN 234
Cdd:PRK13574 196 IYYNLRRINPSPYMFYLKFDERYLIGSSPELLFRVQ-----DNIVETYPIAGTRPRGSDQEEDLKLELELMNSEKDKAEH 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 235 VMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLE 314
Cdd:PRK13574 271 LMLVDLARNDLGKVCVPGTVRVPELMYVEKYSHVQHIVSKVIGTLKKKYNALDVLKATFPAGTVSGAPKPMAMNIIETLE 350
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447140530 315 SSPRGIYCGAIGLLlpTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILEM 382
Cdd:PRK13574 351 EYKRGPYAGAVGFI--SADGNAEFAIAIRTAFLNKDLLRIQAGAGIVYDSNPESEYFETEHKLRALKT 416
|
|
| PLN02445 |
PLN02445 |
anthranilate synthase component I |
167-372 |
4.59e-38 |
|
anthranilate synthase component I
Pssm-ID: 215244 [Multi-domain] Cd Length: 523 Bit Score: 143.28 E-value: 4.59e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 167 YTALLQT-DEIQVASiSPELFFQKGQFNnvdnvIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDI 245
Cdd:PLN02445 286 YMIYLQArGCILVAS-SPEILTRVKKNK-----IVNRPLAGTRRRGKTPEEDKALEKDLLADEKQCAEHIMLVDLGRNDV 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 246 GRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAI 325
Cdd:PLN02445 360 GKVSKAGSVKVEKLMNIERYSHVMHISSTVTGELLDHLTSWDALRAALPVGTVSGAPKVRAMELIDELEVTRRGPYSGGF 439
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447140530 326 GLLLPTEDdkMIFNIPIRTI------------EYK----------YGQAiygvGAGITIDSKPKDEVNE 372
Cdd:PLN02445 440 GGVSFTGD--MDIALALRTMvfptaarydtmySYKdtnsrrewvaHLQA----GAGIVADSDPEDEYRE 502
|
|
| PRK07093 |
PRK07093 |
para-aminobenzoate synthase component I; Validated |
126-376 |
1.80e-37 |
|
para-aminobenzoate synthase component I; Validated
Pssm-ID: 235932 [Multi-domain] Cd Length: 323 Bit Score: 137.69 E-value: 1.80e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 126 VQQAIVEGETYQVNYTARLtdniyyPISTLY--ERLTQFSNGNYTALLQTDEIqvaSISPELFFqkgqfNNVDNVIISKP 203
Cdd:PRK07093 83 VQEEIQAGNSYLLNLTYPT------PIETNLslEEIFQASKAKYKLLFKDQFV---CFSPEPFV-----RIEDNKISTYP 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 204 MKGTMPRGKTEAEDQqyyktLQTSSKDRAENVMIVDLLRNDIGRISQSgsIKVYKLFFIEAYKT----VFQMTSMVSGTL 279
Cdd:PRK07093 149 MKGTIDASLPNAEEK-----LLNDEKEFAEHATIVDLLRNDLSMVAKN--VRVTRFRYIDKIKTnkgeILQTSSEISGTL 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 280 KTN--TDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLlptedDKMIFN--IPIRTIEYKYGQAIYG 355
Cdd:PRK07093 222 PENwqENIGDILAKLLPAGSITGAPKEKTVEIIEQAEGYERGFYTGVFGYF-----DGESLDsaVMIRFIEQENDGLYFK 296
|
250 260
....*....|....*....|.
gi 447140530 356 VGAGITIDSKPKDEVNEFYAK 376
Cdd:PRK07093 297 SGGGITIDSDLKDEYNELIQK 317
|
|
| PRK13571 |
PRK13571 |
anthranilate synthase component I; Provisional |
123-372 |
6.38e-36 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184152 [Multi-domain] Cd Length: 506 Bit Score: 137.08 E-value: 6.38e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 123 IKRVQQAIVEGETYQVNYTARL-TDNIYYPIStLYeRLTQFSNGN-YTALLQTDEIQ-------VASiSPELFFQKgqfn 193
Cdd:PRK13571 236 VEKLVEEIRAGEAFQVVPSQRFeMDTTADPLD-VY-RVLRVTNPSpYMYLLRVPNSDggtdfsiVGS-SPEALVTV---- 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 194 nVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTS 273
Cdd:PRK13571 309 -TDGRATTHPIAGTRWRGATPEEDALLEKELLADPKERAEHLMLVDLGRNDLGRVCRPGTVRVVDFSHIERYSHVMHLVS 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 274 MVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTED-DkmiFNIPIRTIEYKYGQA 352
Cdd:PRK13571 388 TVTGELAEGRTALDAVTACFPAGTLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFAGDaD---TAIAIRTALMRDGTA 464
|
250 260
....*....|....*....|
gi 447140530 353 IYGVGAGITIDSKPKDEVNE 372
Cdd:PRK13571 465 YVQAGGGVVADSDPDYEDNE 484
|
|
| PabB-fungal |
TIGR01823 |
aminodeoxychorismate synthase, fungal clade; This model represents the fungal clade of a ... |
87-376 |
1.42e-34 |
|
aminodeoxychorismate synthase, fungal clade; This model represents the fungal clade of a para-aminobenzoate synthesis enzyme, aminodeoxychorismate synthase, which acts on chorismate in a pathway that yields PABA, a precursor of folate.
Pssm-ID: 273821 [Multi-domain] Cd Length: 742 Bit Score: 135.03 E-value: 1.42e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 87 SFEKAESINSTYEHqtSYVSKHHFSFVES---SEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPIST---LYERLT 160
Cdd:TIGR01823 440 SFVRKKNIKQSLSW--PFYLPEEIDFVITfpdKEDYAKAFKACQDYLHAGDSYEMCLTTQTKVVPPAVISPdweIYQRLR 517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 161 QFSNGNYTALLQTDEIQVASISPELFFQKGQfnnvDNVIISKPMKGTMPRGKTEAEDQQYYKTLqtSSKDRAENVMIVDL 240
Cdd:TIGR01823 518 QRNPAPFSGFFRLKHIIFLSTSPEKFLEVGM----DTHAKLRPIKGTVKKGPQMNLEKARRILK--TPKEMGENLMILDL 591
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 241 LRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSG------TLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLE 314
Cdd:TIGR01823 592 IRNDLYELVPKNDVHVEELMSVEEHATVYQLVSVVKAhgltsaSKKTRYSGIDVLKHSLPPGSMTGAPKKRSVQLLQDVE 671
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447140530 315 SSPRGIYCGAIGLLLPTEDDKmiFNIPIRTIeYKYGQAIY---GVGAGITIDSKPKDEVNEFYAK 376
Cdd:TIGR01823 672 GGARGIYSGVTGYWDVNGNGD--FSVNIRCA-FSYNGGTSwriGAGGAVTVLSTPEGELEEMYNK 733
|
|
| PRK06404 |
PRK06404 |
anthranilate synthase component I; Reviewed |
86-378 |
8.90e-34 |
|
anthranilate synthase component I; Reviewed
Pssm-ID: 102361 [Multi-domain] Cd Length: 351 Bit Score: 128.45 E-value: 8.90e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 86 YSFEKAESINSTYEHQTSYVSKHHFSFveSSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIyypisTLYERLTQFSNG 165
Cdd:PRK06404 76 YSMDPETSYKRNIERKSFKTVKLKGNY--NDISLSLKIKELIELIRAGEVLQVVISREFEANI-----DFKEKLSEFINN 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 166 N---YTALLQTDEIQVASISPElffqkGQFNNVDNVIISKPMKGTMPRGKTEAEdqqyyktLQTSSKDRAENVMIVDLLR 242
Cdd:PRK06404 149 DrsrYVFYYRFGKYRVVGSSPE-----NVFTVNGNIINVDPIAGTYDDKILSNE-------LLNSEKDKLEHRMLLDLAR 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 243 NDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLkTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYC 322
Cdd:PRK06404 217 NDLSKFADIGTLNVDKVMKIEEFSSVKHLVSQVTAKF-SNASYRDILASMFPAGTVSGSPKERAIEIINKYEETPRGPYG 295
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 447140530 323 GAIGLllpTEDDKMIFNIPIRTIeYKYGQAIYG-VGAGITIDSKPKDEVNEFYAKTK 378
Cdd:PRK06404 296 GAIGI---ISKGYTDMALVIRTA-YSHGNGFRVrAGAGIVKDSDPEDEVNEIYSKAR 348
|
|
| PRK13567 |
PRK13567 |
anthranilate synthase component I; Provisional |
78-380 |
1.99e-33 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184148 [Multi-domain] Cd Length: 468 Bit Score: 129.49 E-value: 1.99e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 78 KDDIYAVA---YSFEKAESINSTYEHQTSYVSKHHF-----SFVESSEVMMTNI---------KRVQQAIVEGETYQV-- 138
Cdd:PRK13567 145 KDELYIIAtnqFSNSTKSDLENRVNKSIEDLTKIQPfmptqDFDFKTKEIQSNIseerfiemiQYFKEKITEGDMFQVvp 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 139 ----NYTARLTDNIYYPISTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGqfnnvDNVIISKPMKGTMPRGKTE 214
Cdd:PRK13567 225 sriyKYAHHASQHLNQLSFQLYQNLKRQNPSPYMYYLNIDQPYIVGSSPESFVSVK-----DQIVTTNPIAGTIQRGETT 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 215 AEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFP 294
Cdd:PRK13567 300 QIDNENMKQLLNDPKECSEHRMLVDLGRNDIHRVSKIGTSKITKLMVIEKYEHVMHIVSEVTGKINQNLSPMTVIANLLP 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 295 CGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDdkMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFY 374
Cdd:PRK13567 380 TGTVSGAPKLRAIERIYEQYPHKRGVYSGGVGYINCNHN--LDFALAIRTMMIDEQYINVEAGCGVVYDSIPEKELNETK 457
|
....*.
gi 447140530 375 AKTKIL 380
Cdd:PRK13567 458 LKAKSL 463
|
|
| PRK13564 |
PRK13564 |
anthranilate synthase component 1; |
203-372 |
2.76e-27 |
|
anthranilate synthase component 1;
Pssm-ID: 237428 [Multi-domain] Cd Length: 520 Bit Score: 113.01 E-value: 2.76e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 203 PMKGTMPRGKT-------------EAEdqqyyktLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVF 269
Cdd:PRK13564 325 PIAGTRPRGRRadgsidrdldsriELE-------LRTDHKELAEHLMLVDLARNDLARICQPGSRYVADLLKVDRYSHVM 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 270 QMTSMVSGTLKTNTDltqILTSLFPC---GSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLlpTEDDKMIFNIPIRTIE 346
Cdd:PRK13564 398 HLVSRVVGELRHDLD---ALHAYRACmnmGTLTGAPKVRAMQLIREVEGQRRGSYGGAVGYL--TGHGDLDTCIVIRSAF 472
|
170 180
....*....|....*....|....*.
gi 447140530 347 YKYGQAIYGVGAGITIDSKPKDEVNE 372
Cdd:PRK13564 473 VENGIATVQAGAGVVLDSDPQSEADE 498
|
|
| PRK13566 |
PRK13566 |
anthranilate synthase component I; |
153-376 |
2.47e-22 |
|
anthranilate synthase component I;
Pssm-ID: 237429 [Multi-domain] Cd Length: 720 Bit Score: 98.84 E-value: 2.47e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 153 STLYERLTQFSNGNYTALLQT-DEIQVASISPELFFQkgqfnnVDNVIISK-PMKGTMPRGKTEAEDQQYYKTLQTSSKD 230
Cdd:PRK13566 280 SEIFRRLKEINPSPYGFFINLgDGEYLVGASPEMFVR------VEGRRVETcPISGTIKRGADAIGDAEQIRKLLNSKKD 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 231 RAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTD-LTQILTSLFPCgSITGAPKLNTMKY 309
Cdd:PRK13566 354 ESELTMCTDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHVEGRLRPGFDaLDAFLTHAWAV-TVTGAPKLWAMQF 432
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447140530 310 IKQLESSPRGIYCGAIGLLlpTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAK 376
Cdd:PRK13566 433 IEDHERSPRRWYGGAVGMV--GFDGDMNTGLTLRTIRIKDGVAEVRVGATLLFDSDPEAEEAETELK 497
|
|
| PRK06772 |
PRK06772 |
salicylate synthase; |
115-372 |
9.06e-17 |
|
salicylate synthase;
Pssm-ID: 102546 [Multi-domain] Cd Length: 434 Bit Score: 81.32 E-value: 9.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 115 SSEVMMTNIKRVQQAIVEGETYQV--NYTARLTDNIYYPISTLYERltQFSNGNYTALLQTDEIQVASISPELFFqkgqf 192
Cdd:PRK06772 171 NGEAYKQQVARAVAEIRRGEYVKVivSRAIPLPSRIDMPATLLYGR--QANTPVRSFMFRQEGREALGFSPELVM----- 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 193 NNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMT 272
Cdd:PRK06772 244 SVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQHLG 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 273 SMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLlptEDDKMIFNIPIRTIEYKYGQA 352
Cdd:PRK06772 324 SGVSGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLL---DDTRFDAALVLRSVFQDSQRC 400
|
250 260
....*....|....*....|
gi 447140530 353 IYGVGAGITIDSKPKDEVNE 372
Cdd:PRK06772 401 WIQAGAGIIAQSTPERELTE 420
|
|
| PRK07912 |
PRK07912 |
salicylate synthase; |
170-372 |
5.18e-15 |
|
salicylate synthase;
Pssm-ID: 169151 [Multi-domain] Cd Length: 449 Bit Score: 75.98 E-value: 5.18e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 170 LLQTDEIQVASISPELFFQKgqfnNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRIS 249
Cdd:PRK07912 237 LLRLGGIRALGYSPELVTAV----RADGVVITEPLAGTRAFGRGAAIDRLARDDLESNSKEIVEHAISVRSSLAEITEIA 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 250 QSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLL 329
Cdd:PRK07912 313 EPGSAAVIDFMTVRERGSVQHLGSTVRGRLDASSDRMDALEALFPAVTASGIPKAAGVDAIFRLDEAPRGLYSGAVVMLS 392
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 447140530 330 PteDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNE 372
Cdd:PRK07912 393 A--DGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEE 433
|
|
| PLN02786 |
PLN02786 |
isochorismate synthase |
71-377 |
9.60e-15 |
|
isochorismate synthase
Pssm-ID: 178383 [Multi-domain] Cd Length: 533 Bit Score: 75.59 E-value: 9.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 71 MCSHSLAKDDiyAVAYSFEKA-ESINSTYEHQTSYVSKHHFSFVESSEVMMTN----------IKRVQQAIVEGETYQVN 139
Cdd:PLN02786 205 MLAATIAWDD--ALSWTWENAiEALQETMLQVSSVVMKLRKESLGVSVLSKNHvpskgawhlaVNKALQIIKRKSSPLKK 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 140 YT-AR----LTDNIYYPISTLyeRLTQFSNGN-YTALLQTDEIQvASI--SPELFFQKGQFNnvdnvIISKPMKGTMPRG 211
Cdd:PLN02786 283 VVlARssriITDTDIDPIAWL--ACLQVEGQNaYQFCLQPPDAP-AFIgnTPEQLFHRKGLG-----VCSEALAATRPRG 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 212 KTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLffIEAYKTVFQMTSMVSGTLKTNTDLTQILTS 291
Cdd:PLN02786 355 GSSARDLQIELDLLTSPKDDLEFSIVRENIREKLEAICDRVVVEPHKA--IRKLARVQHLYAQLAGRLRSEDDEFDILAA 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 292 LFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDDkmiFNIPIRT--IEYKYGQAIYGvGAGITIDSKPKDE 369
Cdd:PLN02786 433 LHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWFGGGESE---FAVGIRSalVEKGLGALIYA-GTGIVEGSNPSSE 508
|
....*...
gi 447140530 370 VNEFYAKT 377
Cdd:PLN02786 509 WNELELKI 516
|
|
| PRK07054 |
PRK07054 |
isochorismate synthase; |
206-372 |
4.29e-13 |
|
isochorismate synthase;
Pssm-ID: 235920 [Multi-domain] Cd Length: 475 Bit Score: 70.18 E-value: 4.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 206 GTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSI----KVYKLFFIEayktvfQMTSMVSGTLKT 281
Cdd:PRK07054 281 GTIARGADPAEDARLGAALMASAKDRLEHALVVDAIRAALAPLSRALDIpdqpSLHRLPRLQ------HLSTPIRATLAP 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 282 NTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDDKmiFNIPIRTIEYKYGQAIYGVGAGIT 361
Cdd:PRK07054 355 DATLLQVVAALHPTPAVGGHPRAAALDYIRAHEGFDRGWYAAPIGWLDAHGNGD--FAVALRSALITGGACRLFAGCGIV 432
|
170
....*....|.
gi 447140530 362 IDSKPKDEVNE 372
Cdd:PRK07054 433 ADSEPASEYRE 443
|
|
| MenF |
COG1169 |
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ... |
182-326 |
1.03e-12 |
|
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440783 [Multi-domain] Cd Length: 353 Bit Score: 68.64 E-value: 1.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 182 SPELFFQKgqfnnVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAEN--V--MIVDLLRNDIGRISQSGSIKVY 257
Cdd:COG1169 157 SPERLVRR-----RGGQLTTEALAGTAPRGADPEEDAALAAALLASEKDRREHalVvdSIREALAPLCSSLDVPEEPELL 231
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447140530 258 KLffieayKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIG 326
Cdd:COG1169 232 RL------RNVQHLATPITGTLDPGVSALDLAAALHPTPAVGGTPREAALALIRELEPFDRGWYAGPVG 294
|
|
| PRK06923 |
PRK06923 |
isochorismate synthase DhbC; Validated |
113-376 |
5.07e-12 |
|
isochorismate synthase DhbC; Validated
Pssm-ID: 235886 [Multi-domain] Cd Length: 399 Bit Score: 66.68 E-value: 5.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 113 VESSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPIST--LYERLTQFSNGNYTALL----QTDEIQVASI--SPE 184
Cdd:PRK06923 118 VPDPEVYMNGVKQGIAKIQDGDLKKIVLSRSLDVKSSEKIDKqkLLRELAEHNKHGYTFAVnlpkDENENSKTLIgaSPE 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 185 LFFQKGQFNnvdnvIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSgsIKVYKLFFIEA 264
Cdd:PRK06923 198 LLVSRHGMQ-----VISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYCHT--LHVPEKPSVIH 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447140530 265 YKTVFQMTSMVSGTLK-TNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDDKMIfnIPIR 343
Cdd:PRK06923 271 TEAMWHLSTEVKGELKdPNTSSLELAIALHPTPAVCGTPTEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWI--VTIR 348
|
250 260 270
....*....|....*....|....*....|...
gi 447140530 344 TIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAK 376
Cdd:PRK06923 349 CAEVEENTLRLYAGAGVVAESKPEDELAETSAK 381
|
|
| |
