|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
8-356 |
0e+00 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 622.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 8 MTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLTLLICYQA 87
Cdd:PRK10755 2 ISLRRRLLLTIGLILLVFQLISVFWLWHESTEQIQLLVQATLSARNNDEHVMKEIREAVASLLVPSLVMVSLTLLICFQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 88 VRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSGVRLHLEL 167
Cdd:PRK10755 82 VRWITRPLAELQKELEARTADNLTPIAIHSSTLEIEAVTSALNQLVSRLTSTLDQERLFTADVAHELRTPLAGIRLHLEL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 168 LSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPESAADVVV 247
Cdd:PRK10755 162 LEKQHHIDVAPLIARLDQMMHTVEQLLQLARAGQSFSSGHYQTVKLLEDVILPSQDELSEMLEQRQQTLLLPESAADITV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 248 RGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPD-AIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGLGLSIVS 326
Cdd:PRK10755 242 QGDATLLRLLLRNLVENAHRYSPEGSTITIKLSQEDGgAVLAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVS 321
|
330 340 350
....*....|....*....|....*....|
gi 447134933 327 RITQLHQGQFFLQNRTERTGTRAWVLLKKA 356
Cdd:PRK10755 322 RITQLHHGQFFLQNRQERSGTRAWVWLPKA 351
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
241-351 |
1.40e-46 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 154.10 E-value: 1.40e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 241 SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSR-YGGIG 319
Cdd:cd16940 1 SAADIQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLSADDGAVIRVEDNGPGIDEEELEALFERFYRSDGQnYGGSG 80
|
90 100 110
....*....|....*....|....*....|..
gi 447134933 320 LGLSIVSRITQLHQGQFFLQNRtERTGTRAWV 351
Cdd:cd16940 81 LGLSIVKRIVELHGGQIFLGNA-QGGGLEAWV 111
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
1-356 |
2.03e-45 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 159.72 E-value: 2.03e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 1 MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT 80
Cdd:COG5002 23 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 81 LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG 160
Cdd:COG5002 103 ILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRREFVANVSHELRTPLTS 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 161 VRLHLELLSKTHNVDVAPLIARLDQMMDS-------VSQLLQLARVGQSFSSGNYQEV---KLLEDVIlpsyDELNTMLE 230
Cdd:COG5002 183 IRGYLELLLDGAADDPEERREYLEIILEEaerlsrlVNDLLDLSRLESGELKLEKEPVdlaELLEEVV----EELRPLAE 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 231 TRQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPD-AIMAVEDEGPGIDESKCGKLSEAFV 309
Cdd:COG5002 259 EKGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDqVRISVRDTGIGIPEEDLPRIFERFY 338
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 447134933 310 RMDS----RYGGIGLGLSIVSRITQLHQGQFFLQNRTERtGTRAWVLLKKA 356
Cdd:COG5002 339 RVDKsrsrETGGTGLGLAIVKHIVEAHGGRIWVESEPGK-GTTFTITLPLA 388
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
41-356 |
2.14e-45 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 158.15 E-value: 2.14e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 41 IQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLTLLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTL 120
Cdd:COG0642 8 LVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 121 EIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSGVRLHLELLSKTHNVDVAPLIARL----DQMMDSVSQLLQL 196
Cdd:COG0642 88 LLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEELDEEQREYLETIlrsaDRLLRLINDLLDL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 197 ARVGQSFSSGNYQEV---KLLEDVIlpsyDELNTMLETRQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGT 273
Cdd:COG0642 168 SRLEAGKLELEPEPVdlaELLEEVV----ELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 274 HITIHISADPDAIM-AVEDEGPGIDESKCGKLSEAFVRMDS--RYGGIGLGLSIVSRITQLHQGQFFLQNRTERtGTRAW 350
Cdd:COG0642 244 TVTVSVRREGDRVRiSVEDTGPGIPPEDLERIFEPFFRTDPsrRGGGTGLGLAIVKRIVELHGGTIEVESEPGK-GTTFT 322
|
....*.
gi 447134933 351 VLLKKA 356
Cdd:COG0642 323 VTLPLA 328
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
146-356 |
7.07e-43 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 148.90 E-value: 7.07e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 146 FTADVAHELRTPLSGVRLHLELLSKTHNVDVAPLIARLDQMMDS-------VSQLLQLARVGQSFSSGNYQEVKLlEDVI 218
Cdd:COG2205 19 FLANVSHELRTPLTSILGAAELLLDEEDLSPEERRELLEIIRESaerllrlIEDLLDLSRLESGKLSLELEPVDL-AELL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 219 LPSYDELNTMLETRQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPD-AIMAVEDEGPGID 297
Cdd:COG2205 98 EEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREGDgVRISVSDNGPGIP 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447134933 298 ESKCGKLSEAFVRMDS--RYGGIGLGLSIVSRITQLHQGQFFLQNRtERTGTRAWVLLKKA 356
Cdd:COG2205 178 EEELERIFERFYRGDNsrGEGGTGLGLAIVKRIVEAHGGTIWVESE-PGGGTTFTVTLPLA 237
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
66-343 |
1.23e-36 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 137.47 E-value: 1.23e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 66 VASLIVPGVFMVSLTLLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERL 145
Cdd:PRK10337 160 VAGQLIPWLVALPIMLIILMVLLGRELAPLKKLALALRMRDPDSETPLNATGVPSEVRPLVEALNQLFARTHAMMVRERR 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 146 FTADVAHELRTPLSGVRLHLELLSKTHNVDVA--PLIARLDQMMDS----VSQLLQLARVGQSFSSGNYQEVKLLEdvIL 219
Cdd:PRK10337 240 FTSDAAHELRSPLAALKVQTEVAQLSDDDPQArkKALLQLHAGIDRatrlVDQLLTLSRLDSLDNLQDVAEIPLED--LL 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 220 PSydELNTMLETRQQ---TLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPdaiMAVEDEGPGI 296
Cdd:PRK10337 318 QS--AVMDIYHTAQQagiDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARN---FTVRDNGPGV 392
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 447134933 297 DESKCGKLSEAFVRMDSR-YGGIGLGLSIVSRITQLHQGQFFLQNRTE 343
Cdd:PRK10337 393 TPEALARIGERFYRPPGQeATGSGLGLSIVRRIAKLHGMNVSFGNAPE 440
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
133-335 |
1.01e-29 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 116.54 E-value: 1.01e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 133 VTRLTTTLDNERLFTADVAHELRTPLSGVRLHLELLSKTHNVDVAPLIARLDQM------MDS-VSQLLQLARVGQSFSS 205
Cdd:TIGR02966 104 VTRLRRLEQMRRDFVANVSHELRTPLTVLRGYLETLADGPDEDPEEWNRALEIMleqsqrMQSlVEDLLTLSRLESAASP 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 206 GNYQEVKLLEdVILPSYDELNTMLETRQQTLLLpESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPD- 284
Cdd:TIGR02966 184 LEDEPVDMPA-LLDHLRDEAEALSQGKNHQITF-EIDGGVDVLGDEDELRSAFSNLVSNAIKYTPEGGTITVRWRRDGGg 261
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 447134933 285 AIMAVEDEGPGIDESKCGKLSEAFVRMD---SR-YGGIGLGLSIVSRITQLHQGQ 335
Cdd:TIGR02966 262 AEFSVTDTGIGIAPEHLPRLTERFYRVDksrSRdTGGTGLGLAIVKHVLSRHHAR 316
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
249-356 |
1.42e-25 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 98.88 E-value: 1.42e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 249 GDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVEDEGPGIDESKCGKLSEAFVRMD---SRYGGIGLGLSI 324
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVeITVEDNGPGIPPEDLEKIFEPFFRTDkrsRKIGGTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|..
gi 447134933 325 VSRITQLHQGQFFLQNRTERtGTRAWVLLKKA 356
Cdd:smart00387 81 VKKLVELHGGEISVESEPGG-GTTFTITLPLE 111
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
249-356 |
3.24e-25 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 98.21 E-value: 3.24e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 249 GDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSR-YGGIGLGLSIVSR 327
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRgGGGTGLGLSIVRK 80
|
90 100
....*....|....*....|....*....
gi 447134933 328 ITQLHQGQFFLQNRtERTGTRAWVLLKKA 356
Cdd:pfam02518 81 LVELLGGTITVESE-PGGGTTVTLTLPLA 108
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
88-343 |
4.90e-25 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 104.99 E-value: 4.90e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 88 VRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLvTRLTTTLDNER-LFTADVAHELRTPLSGVRLHLE 166
Cdd:PRK09467 174 IRIQNRPLVALEHAALQVGKGEIPPPLREYGASEVRSVTRAFNQM-AAGIKQLEDDRtLLMAGVSHDLRTPLTRIRLATE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 167 LLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVIL--PSYDelntmletRQQTLLLPESAAD 244
Cdd:PRK09467 253 MMSEEDGYLAESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLNALLGEVIAaeSGYE--------REIETALQPGPIE 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 245 VVVRGDAtlLRMLLRNLVENAHRYspeGTHiTIHISADPD---AIMAVEDEGPGIDESKCGKLSEAFVRMDSRYG--GIG 319
Cdd:PRK09467 325 VPMNPIA--IKRALANLVVNAARY---GNG-WIKVSSGTEgkrAWFQVEDDGPGIPPEQLKHLFQPFTRGDSARGssGTG 398
|
250 260
....*....|....*....|....
gi 447134933 320 LGLSIVSRITQLHQGQFFLQNRTE 343
Cdd:PRK09467 399 LGLAIVKRIVDQHNGKVELGNSEE 422
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
151-356 |
5.76e-25 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 105.31 E-value: 5.76e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 151 AHELRTPLSGVRLHLELLSK----------THNVDVAPliARLDQMMDsvsQLLQLARVGQSfssgnyQEVKLLEDVilp 220
Cdd:PRK11100 264 THELKSPLAAIRGAAELLQEdpppedrarfTGNILTQS--ARLQQLID---RLLELARLEQR------QELEVLEPV--- 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 221 sydELNTMLET---------RQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVE 290
Cdd:PRK11100 330 ---ALAALLEElveareaqaAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVaLSVE 406
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447134933 291 DEGPGIDESKCGKLSEAF---VRMDSRYGGIGLGLSIVSRITQLHQGQFFLQNRTErTGTRAWVLLKKA 356
Cdd:PRK11100 407 DQGPGIPDYALPRIFERFyslPRPANGRKSTGLGLAFVREVARLHGGEVTLRNRPE-GGVLATLTLPRH 474
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
81-356 |
6.42e-25 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 104.66 E-value: 6.42e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 81 LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAInQLVTRLtttLDNERL-----FTADVAHELR 155
Cdd:COG5000 138 LLPELDLAELLREALERGWQEEIELTRDGRRTLLVRASPLRDDGYVIVF-DDITEL---LRAERLaawgeLARRIAHEIK 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 156 TPLSGVRLHLELLSKTHNVDVAPLIARLDQMMDS-----------VSQLLQLARVGQSfssgNYQEV---KLLEDVIlps 221
Cdd:COG5000 214 NPLTPIQLSAERLRRKLADKLEEDREDLERALDTiirqvdrlkriVDEFLDFARLPEP----QLEPVdlnELLREVL--- 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 222 yDELNTMLETRQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVEDEGPGIDESK 300
Cdd:COG5000 287 -ALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRVrIEVSDNGPGIPEEV 365
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 447134933 301 CGKLSEAFVrmDSRYGGIGLGLSIVSRITQLHQGQFFLQNRTERtGTRAWVLLKKA 356
Cdd:COG5000 366 LERIFEPFF--TTKPKGTGLGLAIVKKIVEEHGGTIELESRPGG-GTTFTIRLPLA 418
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
2-335 |
1.08e-24 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 104.87 E-value: 1.08e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 2 RFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLTL 81
Cdd:COG4251 141 ALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLS 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 82 LICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTldNERL--FTADVAHELRTPLS 159
Cdd:COG4251 221 LGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAELERS--NEELeqFAYVASHDLREPLR 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 160 GVRLHLELLSKTHNVDVAPLIAR-LDQMMDSVSQ-------LLQLARVGQSfsSGNYQEV---KLLEDVIlpsyDELNTM 228
Cdd:COG4251 299 KISGFSQLLEEDYGDKLDEEGREyLERIRDAAERmqaliddLLAYSRVGRQ--ELEFEPVdlnELLEEVL----EDLEPR 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 229 LETRQQTLllpESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPD---AIMAVEDEGPGIDESKCGKLS 305
Cdd:COG4251 373 IEERGAEI---EVGPLPTVRGDPTLLRQVFQNLISNAIKYSRPGEPPRIEIGAEREggeWVFSVRDNGIGIDPEYAEKIF 449
|
330 340 350
....*....|....*....|....*....|..
gi 447134933 306 EAFVRMDSR--YGGIGLGLSIVSRITQLHQGQ 335
Cdd:COG4251 450 EIFQRLHSRdeYEGTGIGLAIVKKIVERHGGR 481
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
52-334 |
9.33e-24 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 101.70 E-value: 9.33e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 52 RNNDRHIMHEIREAvasLIVPGVFMVSLTLLICYQAVRRITRPLAELQKELEARTADNLA-PIAIHSSTLEIESVVSAIN 130
Cdd:TIGR01386 152 INAHTHLLDALRKW---LILIAVLLVLLTALLGWWITRLGLEPLRRLSAVAARISPESLDqRLDPSRAPAELRELAQSFN 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 131 QLVTRLTTTLDNERLFTADVAHELRTPLSGVRLHLE-LLSKTHNVD-----VAPLIARLDQMMDSVSQLLQLARVGQSFS 204
Cdd:TIGR01386 229 AMLGRLEDAFQRLSQFSADLAHELRTPLTNLLGQTQvALSQPRTGEeyrevLESNLEELERLSRMVSDMLFLARADNGQL 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 205 SGNYQEVKL---LEDVIlpsyDELNTMLETRQQTLLLPESAadvVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISA 281
Cdd:TIGR01386 309 ALERVRLDLaaeLAKVA----EYFEPLAEERGVRIRVEGEG---LVRGDPQMFRRAISNLLSNALRHTPDGGTITVRIER 381
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 447134933 282 DPDAI-MAVEDEGPGIDESKCGKLSEAFVRMD-SRYG---GIGLGLSIVSRITQLHQG 334
Cdd:TIGR01386 382 RSDEVrVSVSNPGPGIPPEHLSRLFDRFYRVDpARSNsgeGTGLGLAIVRSIMEAHGG 439
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
59-335 |
6.68e-23 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 99.46 E-value: 6.68e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 59 MHEIREAVASLIVPGVFMVSLTLLICYQAVRRITRPLAELQKELEARTADNL-APIAIHSSTLEIESVVSAINQLVTRLT 137
Cdd:PRK09835 177 LHYINDLKNKLIMTASVISLLIVFIVLLAVHKGHAPIRSVSRQIQNITSKDLdVRLDPQTVPIELEQLVLSFNHMIERIE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 138 TTLDNERLFTADVAHELRTPLSGVRLHLEL-LSKTHNV----DVapLIARLDQ---MMDSVSQLLQLArvgQSFSSGNYQ 209
Cdd:PRK09835 257 DVFTRQSNFSADIAHEIRTPITNLITQTEIaLSQSRSQkeleDV--LYSNLEEltrMAKMVSDMLFLA---QADNNQLIP 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 210 EVKLLE--DVILPSYDELNTMLETRQQTLLLPESAAdvVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI- 286
Cdd:PRK09835 332 EKKMLDlaDEVGKVFDFFEAWAEERGVELRFVGDPC--QVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVq 409
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 447134933 287 MAVEDEGPGIDESKCGKLSEAFVRMD---SRYG-GIGLGLSIVSRITQLHQGQ 335
Cdd:PRK09835 410 LVVENPGTPIAPEHLPRLFDRFYRVDpsrQRKGeGSGIGLAIVKSIVVAHKGT 462
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
79-334 |
1.16e-20 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 92.58 E-value: 1.16e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 79 LTLLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPL 158
Cdd:NF012163 176 LAALAAFLLARGLLAPVKRLVEATHRLAAGDYTTRVTPTSNDELGKLAQDFNQLASTLEKNEQMRRDFMADISHELRTPL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 159 SGVRLHLELLSKthnvDVAPLI-ARLDQMMDSVSQLLQ----LARVGQSFSSG-NYQEVKL-LEDVILPSYDELNTMLET 231
Cdd:NF012163 256 AVLRAELEAIQD----GIRKFTpESLDSLQAEVGTLTKlvddLHDLSMSDEGAlAYQKASVdLVPLLEVEGGAFRERFAS 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 232 RQQTLL--LPESAadvVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVEDEGPGIDESKCGKLSEAF 308
Cdd:NF012163 332 AGLELEvsLPDSS---LVFGDRDRLMQLFNNLLENSLRYTDSGGSLHISASQRPKEVtLTVADSAPGVSDEQLARLFERF 408
|
250 260 270
....*....|....*....|....*....|
gi 447134933 309 VRMDSRY----GGIGLGLSIVSRITQLHQG 334
Cdd:NF012163 409 YRVEVSRnrasGGSGLGLAISLNIVQAHGG 438
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
128-335 |
2.02e-20 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 91.59 E-value: 2.02e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 128 AINQLVTRLTTTLDNERLFTADVAHELRTPLSGVRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQsfssgn 207
Cdd:PRK10604 197 AFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSDNLSAAESQALNRDIGQLEALIEELLTYARLDR------ 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 208 yQEVKL-LEDVILPSY-----DELNTMLETRQQTLLLPESAAdvVVRGDATLLRMLLRNLVENAHRYSpeGTHITIHISA 281
Cdd:PRK10604 271 -PQNELhLSEPDLPAWlsthlADIQAVTPEKTVRLDTPHQGD--YGALDMRLMERVLDNLLNNALRYA--HSRVRVSLLL 345
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 447134933 282 DPD-AIMAVEDEGPGIDESKCGKLSEAFVRMD-SR---YGGIGLGLSIVSRITQLHQGQ 335
Cdd:PRK10604 346 DGNqACLIVEDDGPGIPPEERERVFEPFVRLDpSRdraTGGCGLGLAIVHSIALAMGGS 404
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
142-335 |
2.35e-20 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 91.96 E-value: 2.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 142 NERL-----FTADVAHELRTPLSGVRLHLELLSKTHNVDVAP----LIARLDQMMDSVSQLLQLARVgqsfSSGNYQEV- 211
Cdd:COG5809 264 SEKLsvvgeLAAGIAHEIRNPLTSLKGFIQLLKDTIDEEQKTyldiMLSELDRIESIISEFLVLAKP----QAIKYEPKd 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 212 --KLLEDVI---LPSYDELNTMLETrqqtlllpESAADVV-VRGDATLLRMLLRNLVENAHRYSPEGTHITIHISA-DPD 284
Cdd:COG5809 340 lnTLIEEVIpllQPQALLKNVQIEL--------ELEDDIPdILGDENQLKQVFINLLKNAIEAMPEGGNITIETKAeDDD 411
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 447134933 285 AIM-AVEDEGPGIDESKCGKLSEAFvrMDSRYGGIGLGLSIVSRITQLHQGQ 335
Cdd:COG5809 412 KVViSVTDEGCGIPEERLKKLGEPF--YTTKEKGTGLGLMVSYKIIEEHGGK 461
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
89-334 |
2.03e-19 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 88.84 E-value: 2.03e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 89 RRITRPLAELQKELEARTADNLApiaIH----SSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSGVRLH 164
Cdd:PRK09470 188 WSLAKPARKLKNAADEVAQGNLR---QHpeleTGPQEFRQAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLA 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 165 LELL-------SKTHNVDVAplIARLDQMmdsVSQLLQLARvgqsfssgnyQEVKL-LEDVILPSYDELNTML------- 229
Cdd:PRK09470 265 TALLrrrqgesKELERIETE--AQRLDSM---INDLLVLSR----------NQQKNhLERETFKANSLWSEVLedakfea 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 230 ETRQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSpeGTHITIHISADPDAIM-AVEDEGPGIDESKCGKLSEAF 308
Cdd:PRK09470 330 EQMGKSLTVSAPPGPWPINGNPNALASALENIVRNALRYS--HTKIEVAFSVDKDGLTiTVDDDGPGVPEEEREQIFRPF 407
|
250 260 270
....*....|....*....|....*....|
gi 447134933 309 VRMDS----RYGGIGLGLSIVSRITQLHQG 334
Cdd:PRK09470 408 YRVDEardrESGGTGLGLAIVENAIQQHRG 437
|
|
| marine_sort_HK |
TIGR03785 |
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is ... |
74-353 |
5.15e-19 |
|
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is paired with an adjacent response regulator (TIGR03787) gene. It co-occurs with a variant sortase enzyme (TIGR03784), usually in the same gene neighborhood, in proteobacterial species most of which are marine, and with an LPXTG motif-containing sortase target conserved protein (TIGR03788). Sortases and LPXTG proteins are far more common in Gram-positive bacteria, where sortase systems mediate attachment to the cell wall or cross-linking of pilin structures. We give this predicted sensor histidine kinase the gene symbol psdS, for Proteobacterial Dedicated Sortase system Sensor histidine kinase.
Pssm-ID: 163497 [Multi-domain] Cd Length: 703 Bit Score: 88.26 E-value: 5.15e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 74 VFMVSLTL-------LICYqAVR---RITRplaeLQKELEARTADN---LAPIAIHSSTLEIESVVSAINQLVTRL---T 137
Cdd:TIGR03785 408 LFNVILAImsigtlaLFGF-ASWiswRIRR----LSDDAEAAIDSQgriSGAIPASRSRDEIGDLSRSFAQMVARLrqyT 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 138 TTLDNerlFTADVAHELRTPLSGVRLHLELLS-------KTHNVDVAPL-IARLDQMMDSVSqllQLARVGQSFSSGNYQ 209
Cdd:TIGR03785 483 HYLEN---MSSRLSHELRTPVAVVRSSLENLElqaleqeKQKYLERAREgTERLSMILNNMS---EATRLEQAIQSAEVE 556
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 210 EVKLLEdvILPSYDELNTMLETRQQ-TLLLPESaaDVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISA-DPDAIM 287
Cdd:TIGR03785 557 DFDLSE--VLSGCMQGYQMTYPPQRfELNIPET--PLVMRGSPELIAQMLDKLVDNAREFSPEDGLIEVGLSQnKSHALL 632
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 288 AVEDEGPGIDESKCGKLSEAFVRM----DSRYGGIGLGLSIVSRITQLHQGQFFLQNRTERTGTRAWVLL 353
Cdd:TIGR03785 633 TVSNEGPPLPEDMGEQLFDSMVSVrdqgAQDQPHLGLGLYIVRLIADFHQGRIQAENRQQNDGVVFRISL 702
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
144-325 |
1.44e-18 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 86.22 E-value: 1.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 144 RLFTADVAHELRTPLSGVRLHLELLSKthNVDVAPLIAR-LDQM------MDS-VSQLLQLARVGQSfssgnyQEVKLLE 215
Cdd:PRK11006 205 RNFFANVSHELRTPLTVLQGYLEMMQD--QPLEGALREKaLHTMreqtqrMEGlVKQLLTLSKIEAA------PTIDLNE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 216 DVILPSYDElntMLETRQQTL------LLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPD-AIMA 288
Cdd:PRK11006 277 KVDVPMMLR---VLEREAQTLsqgkhtITFEVDNSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQgAEFS 353
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 447134933 289 VEDEGPGIDESKCGKLSEAFVRMD---SRY-GGIGLGLSIV 325
Cdd:PRK11006 354 VEDNGPGIAPEHIPRLTERFYRVDkarSRQtGGSGLGLAIV 394
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
18-353 |
4.57e-18 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 84.08 E-value: 4.57e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 18 IGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLTLLICYQAVRRITRPLAE 97
Cdd:COG4191 5 LLLLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 98 LQKELEARTADNLAPIAIHSSTLEIESVVSAINQL---VTRLTTT----LDNERL-----FTADVAHELRTPLSGVRLHL 165
Cdd:COG4191 85 LLLLLLEALLLLLLAALDAEENAELEELERDITELeraEEELRELqeqlVQSEKLaalgeLAAGIAHEINNPLAAILGNA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 166 ELLSK--THNVDVAPLIARLDQMMDS-------VSQLLQLARVgqsfSSGNYQEV---KLLEDVIlpsyDELNTMLETRQ 233
Cdd:COG4191 165 ELLRRrlEDEPDPEELREALERILEGaeraaeiVRSLRAFSRR----DEEEREPVdlnELIDEAL----ELLRPRLKARG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 234 QTLLLPESAADVVVRGDATLLRMLLRNLVENA-----HRYSPEgthITIHISADPDAIM-AVEDEGPGIDESKCGKLSEA 307
Cdd:COG4191 237 IEVELDLPPDLPPVLGDPGQLEQVLLNLLINAidameEGEGGR---ITISTRREGDYVViSVRDNGPGIPPEVLERIFEP 313
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 447134933 308 FVRMDSRYGGIGLGLSIVSRITQLHQGQFFLQNRTERtGTRAWVLL 353
Cdd:COG4191 314 FFTTKPVGKGTGLGLSISYGIVEKHGGRIEVESEPGG-GTTFTITL 358
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
68-334 |
6.55e-18 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 84.69 E-value: 6.55e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 68 SLIVPGVFMVSLTLLICYQAVRRITRPL------AE------LQKELEARTADNLAPIAIHSSTLEiESVVSAINQL--V 133
Cdd:NF040691 189 TLLLGGLALVVLLGLIAWLVTRQVVAPVrsaartAErfaagdLSERMPVKGEDDLARLARSFNQMA-DSLQRQIRQLeeL 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 134 TRLtttldnERLFTADVAHELRTPLSGVRLHLELLSKtHNVDVAPLIAR--------LDQMMDSVSQLLQLARvgqsFSS 205
Cdd:NF040691 268 SRL------QQRFVSDVSHELRTPLTTIRMAADVIHD-SRDDFDPATARsaellhteLDRFESLLSDLLEISR----FDA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 206 GNYQ---EVKLLEDVILPSYDELNTMLETRQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSpEGTHITIHISAD 282
Cdd:NF040691 337 GAAEldvEPVDLRPLVRRVVDALRQLAERAGVELRVDAPGTPVVAEVDPRRVERVLRNLVVNAIEHG-EGKPVVVTVAQD 415
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 447134933 283 PDAI-MAVEDEGPGIDESKCGKLSEAFVRMD-SR---YGGIGLGLSIVSRITQLHQG 334
Cdd:NF040691 416 DTAVaVTVRDHGVGLKPGEVALVFDRFWRADpARartTGGTGLGLAIALEDARLHGG 472
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
117-334 |
1.33e-17 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 83.53 E-value: 1.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 117 SSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSGVRLHLELLS----KTHNVDVAPL---IARLDQMMDS 189
Cdd:PRK10549 214 TSRDELGRLAQDFNQLASTLEKNEQMRRDFMADISHELRTPLAVLRGELEAIQdgvrKFTPESVASLqaeVGTLTKLVDD 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 190 VSQLLQLARVGQSFSSGNYQEVKLLEdVILPSYDELntmLETRQQTL--LLPESAadvVVRGDATLLRMLLRNLVENAHR 267
Cdd:PRK10549 294 LHQLSLSDEGALAYRKTPVDLVPLLE-VAGGAFRER---FASRGLTLqlSLPDSA---TVFGDPDRLMQLFNNLLENSLR 366
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 447134933 268 YSPEGTHITIHISADPDA-IMAVEDEGPGIDESKCGKLSEAFVRMD-SR---YGGIGLGLSIVSRITQLHQG 334
Cdd:PRK10549 367 YTDSGGSLHISAEQRDKTlRLTFADSAPGVSDEQLQKLFERFYRTEgSRnraSGGSGLGLAICLNIVEAHNG 438
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
254-354 |
2.86e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 76.38 E-value: 2.86e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 254 LRMLLRNLVENAHRYSPEGtHITIHISADPD------AIMAVEDEGPGIDESKCGKLSEAFVRMDS----RYGGIGLGLS 323
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEG-EVTLRVSLEEEeedgvqLRFSVEDTGIGIPEEQQARLFEPFSQADSsttrKYGGTGLGLA 79
|
90 100 110
....*....|....*....|....*....|.
gi 447134933 324 IVSRITQLHQGQFFLQNRtERTGTRAWVLLK 354
Cdd:cd16922 80 ISKKLVELMGGDISVESE-PGQGSTFTFTLP 109
|
|
| AdeS_HK |
NF012226 |
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component ... |
79-342 |
3.14e-17 |
|
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component regulatory system for the AdeABC efflux pump can confer adaptive resistance to certain antibiotics, including tigecycline.
Pssm-ID: 411090 [Multi-domain] Cd Length: 353 Bit Score: 81.58 E-value: 3.14e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 79 LTLLICYQAVRRITRP---LAELQKE-----LEARTADNlapiAIHSStlEIESVVSAINQLVTRLTTTLDNERLFTADV 150
Cdd:NF012226 72 ISLIIGMKLAQRFIVPinfLADAAKKisqgdLSARAEDS----QIHSA--EISELMHNFNDMAQKLESSVKNAQVWNAAI 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 151 AHELRTP---LSGvRLHlELLSKTHNVDVAPLIARLDQmMDSVSQLLQLARVGQSFSSG----NYQEVKLLEDVilpsyD 223
Cdd:NF012226 146 AHELRTPitiLQG-RLQ-GILDGVFEPDPALFKSLLNQ-VEGLSHLVEDLRTLSLVENQqlrlNYESVDLKDSI-----E 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 224 ELNTMLETR-QQTLLLPES-AADVVVRGDATLLRMLLRNLVENAHRYSPEGThITIHISADPDA-IMAVEDEGPGIDESK 300
Cdd:NF012226 218 KVLKMFEDRlEQAQLTIVLnLTATPVFCDRRRIEQVLIALIDNAIRYANAGK-LKISSSVIQDDwILQIEDEGPGIAEEY 296
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 447134933 301 CGKLSEAFVRM-DSR---YGGIGLGLSIVSRITQLHQGQFFLQNRT 342
Cdd:NF012226 297 QQDLFNPFFRLeQSRnkeFGGTGLGLAVVHAIVIAHKGSIEYSNSQ 342
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
147-334 |
1.00e-16 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 80.93 E-value: 1.00e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 147 TADVAHELRTPLSGVRLHLELLS-----KTHNVDVapLIARLDQMMDSVSQLLQLARVgqsfSSGNYQEV---KLLEDVI 218
Cdd:COG5805 291 AAGIAHEIRNPLTSIKGFLQLLQpgiedKEEYFDI--MLSELDRIESIISEFLALAKP----QAVNKEKEninELIQDVV 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 219 lpsydelnTMLET----RQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHI-SADPDAIMAVEDEG 293
Cdd:COG5805 365 --------TLLETeailHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTeEEDNSVIIRVIDEG 436
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 447134933 294 PGIDESKCGKLSEAFVRMDSRygGIGLGLSIVSRITQLHQG 334
Cdd:COG5805 437 IGIPEERLKKLGEPFFTTKEK--GTGLGLMVSYKIIENHNG 475
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
148-343 |
1.18e-16 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 81.24 E-value: 1.18e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 148 ADVAHELRTPLSGVRLHLELLS---KTHNVDVAPLIARLDQMMDS----VSQLLQLARVgqsfSSGNYQ---EVKLLEDV 217
Cdd:PRK10490 669 AALSHDLRTPLTVLFGQAEILTldlASEGSPHARQASEIRQQVLNttrlVNNLLDMARI----QSGGFNlrkEWLTLEEV 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 218 ILPSYDELNTMLETRQQTLLLPESAadVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVEDEGPGI 296
Cdd:PRK10490 745 VGSALQMLEPGLSGHPINLSLPEPL--TLIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGERLqLDVWDNGPGI 822
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 447134933 297 DESKCGKLSEAFVRMD--SRYGGIGLGLSIVSRITQLHQGQFFLQNRTE 343
Cdd:PRK10490 823 PPGQEQLIFDKFARGNkeSAIPGVGLGLAICRAIVEVHGGTIWAENRPE 871
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
150-335 |
1.63e-16 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 79.51 E-value: 1.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 150 VAHELRTPLSGVRLHLELLSktHNVDVAPLIARLDQMMDS-------VSQLLQLARvgqsFSSGNYQEV---KLLEDVIl 219
Cdd:COG3852 142 LAHEIRNPLTGIRGAAQLLE--RELPDDELREYTQLIIEEadrlnnlVDRLLSFSR----PRPPEREPVnlhEVLERVL- 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 220 psydelntmletrqqTLLLPESAADVV-----------VRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPD---- 284
Cdd:COG3852 215 ---------------ELLRAEAPKNIRivrdydpslpeVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTRVERQvtlg 279
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 447134933 285 -------AIMAVEDEGPGIDESKCGKLSEAFVRmdSRYGGIGLGLSIVSRITQLHQGQ 335
Cdd:COG3852 280 glrprlyVRIEVIDNGPGIPEEILDRIFEPFFT--TKEKGTGLGLAIVQKIVEQHGGT 335
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
140-335 |
1.65e-16 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 80.57 E-value: 1.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 140 LDNER-LFTADVAHELRTPLSGVRLHLELLSKT--HNVDVAPLIARLDQ-----MMDSVSQLLQLARvgqsFSSGNYQ-- 209
Cdd:NF033092 368 IEQERrEFVANVSHELRTPLTTMRSYLEALADGawKDPELAPRFLGVTQneterMIRLVNDLLQLSR----MDSKDYKln 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 210 -E----VKLLEDVIlpsyDELNTMLETRQQTLL--LPESAADVVVRGDatllRM--LLRNLVENAHRYSPEGTHITIHIS 280
Cdd:NF033092 444 kEwvnfNEFFNYII----DRFEMILKNKNITFKreFPKRDLWVEIDTD----KItqVLDNIISNAIKYSPEGGTITFRLL 515
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 281 ADPD-AIMAVEDEGPGIDESKCGKLSEAFVRMD---SR-YGGIGLGLSIVSRITQLHQGQ 335
Cdd:NF033092 516 ETHNrIIISISDQGLGIPKKDLDKIFDRFYRVDkarSRkMGGTGLGLAIAKEVVEAHGGR 575
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
150-335 |
4.42e-16 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 78.45 E-value: 4.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 150 VAHELRTPLSGVRLHLELLSKTHNVDVAP----LIARLD-------QMMDSVSQ-LLQLARVGQSFSSGNYQEV---KLL 214
Cdd:PRK09303 158 LAHDLRTPLTAASLALETLELGQIDEDTElkpaLIEQLQdqarrqlEEIERLITdLLEVGRTRWEALRFNPQKLdlgSLC 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 215 EDVILpsydELNTMLETRQQTLL------LPEsaadvvVRGDATLLRMLLRNLVENAHRYSPEGTHITI---H------- 278
Cdd:PRK09303 238 QEVIL----ELEKRWLAKSLEIQtdipsdLPS------VYADQERIRQVLLNLLDNAIKYTPEGGTITLsmlHrttqkvq 307
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 447134933 279 ISadpdaimaVEDEGPGIDESKCGKLSEAFVRM--DSRYGGIGLGLSIVSRITQLHQGQ 335
Cdd:PRK09303 308 VS--------ICDTGPGIPEEEQERIFEDRVRLprDEGTEGYGIGLSVCRRIVRVHYGQ 358
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
254-348 |
1.32e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 71.85 E-value: 1.32e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 254 LRMLLRNLVENAHRYSPEGTHITIHISADPD-AIMAVEDEGPGIDESKCGKLSEAFVRMD----SRYGGIGLGLSIVSRI 328
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESgARLSVEDTGPGIPPEHIPRLTERFYRVDiercRNTGGTGLGLAIVKHV 80
|
90 100
....*....|....*....|
gi 447134933 329 TQLHQGQFFLQNRTERtGTR 348
Cdd:cd16952 81 MSRHDARLLIASELGK-GSR 99
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
254-353 |
3.53e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 70.56 E-value: 3.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 254 LRMLLRNLVENAHRYSpeGTHITIHISADPDAI-MAVEDEGPGIDESKCGKLSEAFVRMDSRYG--GIGLGLSIVSRITQ 330
Cdd:cd16950 1 LKRVLSNLVDNALRYG--GGWVEVSSDGEGNRTrIQVLDNGPGIAPEEVDELFQPFYRGDNARGtsGTGLGLAIVQRISD 78
|
90 100
....*....|....*....|...
gi 447134933 331 LHQGQFFLQNRtERTGTRAWVLL 353
Cdd:cd16950 79 AHGGSLTLANR-AGGGLCARIEL 100
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
250-350 |
5.17e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 70.18 E-value: 5.17e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 250 DATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVEDEGPGIDESKCGKLSEAFV---RMDSRYGGIGLGLSIV 325
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIeLLVFDEGSGIPDYALNRVFERFYslpRPHSGQKSTGLGLAFV 80
|
90 100
....*....|....*....|....*
gi 447134933 326 SRITQLHQGQFFLQNRTERTGTRAW 350
Cdd:cd16945 81 QEVAQLHGGRITLRNRPDGVLAFLT 105
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
250-334 |
7.90e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 69.80 E-value: 7.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 250 DATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVEDEGPGIDESKCGKLSEAFVRMDSR----YGGIGLGLSI 324
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVrLDVEDSAPGVSDDQLARLFERFYRVESSrnraSGGSGLGLAI 80
|
90
....*....|
gi 447134933 325 VSRITQLHQG 334
Cdd:cd16946 81 CHNIALAHGG 90
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
258-348 |
8.78e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 69.28 E-value: 8.78e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 258 LRNLVENAHRYSPEgtHITIHISADPDAI-MAVEDEGPGIDESKCGKLSEAFVRMDSRY----GGIGLGLSIVSRITQLH 332
Cdd:cd16949 5 LENVLRNALRYSPS--KILLDISQDGDQWtITITDDGPGVPEDQLEQIFLPFYRVDSARdresGGTGLGLAIAERAIEQH 82
|
90
....*....|....*.
gi 447134933 333 QGQFFLQNRtERTGTR 348
Cdd:cd16949 83 GGKIKASNR-KPGGLR 97
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
148-339 |
1.96e-13 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 71.60 E-value: 1.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 148 ADVAHELRTPLSGVRLHLELLSKThnvdvaPLIARLDQMMDSVSQ-----------LLQLARVGQSFSSGNYQEVKLLed 216
Cdd:PRK15347 403 TTISHEIRTPLNGVLGALELLQNT------PLTAEQMDLADTARQctlsllaiinnLLDFSRIESGQMTLSLEETALL-- 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 217 vilPSYDelNTMLETRQQ---------TLLLPESAADVVVrgDATLLRMLLRNLVENAHRYSPEGtHITIHI-SADPDAI 286
Cdd:PRK15347 475 ---PLLD--QAMLTIQGPaqsksltlrTFVGAHVPLYLHL--DSLRLRQILVNLLGNAVKFTETG-GIRLRVkRHEQQLC 546
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 447134933 287 MAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGLGLSIVSRITQLHQGQFFLQ 339
Cdd:PRK15347 547 FTVEDTGCGIDIQQQQQIFTPFYQADTHSQGTGLGLTIASSLAKMMGGELTLF 599
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
143-354 |
9.77e-13 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 69.23 E-value: 9.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 143 ERL-----FTADVAHELRTPLSGVRLHLELLSKTHNVDVAP----LIAR-LDQMMDSVSQLLQLARVGQSfssgNYQEVK 212
Cdd:PRK11360 385 ERLaalgeLVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQeylsVVLReVDRLNKVIDQLLEFSRPRES----QWQPVS 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 213 LLEDVilpsYDELNTMLETRQQ-----TLLLPESAADVVVrgDATLLRMLLRNLVENAHRYSPEGTHITI--HISADPDA 285
Cdd:PRK11360 461 LNALV----EEVLQLFQTAGVQarvdfETELDNELPPIWA--DPELLKQVLLNILINAVQAISARGKIRIrtWQYSDGQV 534
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447134933 286 IMAVEDEGPGIDESKCGKLSEAFvrMDSRYGGIGLGLSIVSRITQLHQGQFFLQNRTERtGTRAWVLLK 354
Cdd:PRK11360 535 AVSIEDNGCGIDPELLKKIFDPF--FTTKAKGTGLGLALSQRIINAHGGDIEVESEPGV-GTTFTLYLP 600
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
254-339 |
2.86e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 62.34 E-value: 2.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 254 LRMLLRNLVENAHRYSPEGTHITIHISADPDA---IMAVEDEGPGIDESKCGKLSEAFVRMDSR--YGGIGLGLSIVSRI 328
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRPPRIEVGAEDVGeewTFYVRDNGIGIDPEYAEKVFGIFQRLHSReeYEGTGVGLAIVRKI 80
|
90
....*....|.
gi 447134933 329 TQLHQGQFFLQ 339
Cdd:cd16921 81 IERHGGRIWLE 91
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
258-334 |
3.10e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 62.45 E-value: 3.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 258 LRNLVENAHRYSpegtHITIHISA---DPDAIMAVEDEGPGIDESKCGKLSEAFVRMDS----RYGGIGLGLSIVSRITQ 330
Cdd:cd16939 5 LDNLLRNALRYA----HRTVRIALlvsGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPsrdrATGGFGLGLAIVHRVAL 80
|
....
gi 447134933 331 LHQG 334
Cdd:cd16939 81 WHGG 84
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
235-353 |
2.24e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 60.72 E-value: 2.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 235 TLLLPESAADVVVRGDatlLRMLLRNLVENAHRYSPEGTHITIHiSADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSR 314
Cdd:cd16954 22 SLDISPELRFPGERND---LMELLGNLLDNACKWCLEFVEVTAR-QTDGGLHLIVDDDGPGVPESQRSKIFQRGQRLDEQ 97
|
90 100 110
....*....|....*....|....*....|....*....
gi 447134933 315 YGGIGLGLSIVSRITQLHQGQFFLqNRTERTGTRAWVLL 353
Cdd:cd16954 98 RPGQGLGLAIAKEIVEQYGGELSL-SDSPLGGARFEVVF 135
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
250-354 |
5.59e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 59.09 E-value: 5.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 250 DATLLRMLLRNLVENAH-----RYSPEGtHITIHISADPDA--IMAVEDEGPGIDESKCGKLSEAFVrmDSRYGGIGLGL 322
Cdd:cd16944 1 DTTQISQVLTNILKNAAeaiegRPSDVG-EVRIRVEADQDGriVLIVCDNGKGFPREMRHRATEPYV--TTRPKGTGLGL 77
|
90 100 110
....*....|....*....|....*....|..
gi 447134933 323 SIVSRITQLHQGQFFLQNRTERTgtrAWVLLK 354
Cdd:cd16944 78 AIVKKIMEEHGGRISLSNREAGG---ACIRII 106
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
37-330 |
5.83e-11 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 63.77 E-value: 5.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 37 STEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLTLLICYQAV-RRITRPLAE----LQKELEA------- 104
Cdd:PRK11466 301 SSEVSQLVDTIELRNQHGLAHLEKASARGQYSLLLLGMVSLCALILILWRVVyRSVTRPLAEqtqaLQRLLDGdidspfp 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 105 --------------------------RTADNLAPIaIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPL 158
Cdd:PRK11466 381 etagvreldtigrlmdafrsnvhalnRHREQLAAQ-VKARTAELQELVIEHRQARAEAEKASQAKSAFLAAMSHEIRTPL 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 159 SGVRLHLELLSKThnvdvaPLIAR----LDQMMDSVSQLLQLARVGQSFSS--GNYQEVKLLEDVILPSyDELNTMLE-- 230
Cdd:PRK11466 460 YGILGTAQLLADN------PALNAqrddLRAITDSGESLLTILNDILDYSAieAGGKNVSVSDEPFEPR-PLLESTLQlm 532
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 231 ---TRQQTLLLPESAADVV---VRGDATLLRMLLRNLVENAHRYSPEGtHITIHISADPDA-IMAVEDEGPGIDESKCGK 303
Cdd:PRK11466 533 sgrVKGRPIRLATDIADDLptaLMGDPRRIRQVITNLLSNALRFTDEG-SIVLRSRTDGEQwLVEVEDSGCGIDPAKLAE 611
|
330 340
....*....|....*....|....*..
gi 447134933 304 LSEAFVRMDSRYGGIGLGLSIVSRITQ 330
Cdd:PRK11466 612 IFQPFVQVSGKRGGTGLGLTISSRLAQ 638
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
254-336 |
8.01e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 55.47 E-value: 8.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 254 LRMLLRNLVENAHRYSPEGT--HITIHISADPDAIMaVEDEGPGIDESKCGKLSEAFVRMD-SRY-GGIGLGLSIVSRIT 329
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTriYITSFLTDDVVNIM-FKNPSSHPLDFKLEKLFERFYRGDnSRNtEGAGLGLSIAKAII 79
|
....*..
gi 447134933 330 QLHQGQF 336
Cdd:cd16923 80 ELHGGSA 86
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
250-340 |
2.37e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 54.39 E-value: 2.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 250 DATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVEDEGPGIDESKCGKLSEAFVRMD-SRYGG--IGLGLSIV 325
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLyFEIWDNGHGFSEQDLKKALELFYRDDtSRRSGghYGMGLYIA 80
|
90
....*....|....*
gi 447134933 326 SRITQLHQGQFFLQN 340
Cdd:cd16975 81 KNLVEKHGGSLIIEN 95
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
56-334 |
5.20e-09 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 57.34 E-value: 5.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 56 RHIMHEIREAVASLIVPGVFMVSLTLLICYQAVRRITRPLAELQKELEARTADNLAPIAIhSSTLEIESVVSAINQLVTR 135
Cdd:COG2972 146 SELFRGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLVRLEV-SGNDEIGILARSFNEMVER 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 136 LTTTLDNERlftadvAHELRtplsgvRLHLEL---------------------LSKTHNVDvapliaRLDQMMDSVSQLL 194
Cdd:COG2972 225 IKELIEEVY------ELELE------KKEAELkalqaqinphflfntlnsirwLAELEDPE------EAEEMLEALSKLL 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 195 QlarvgQSFSSGN-----YQEVKLLEdvilpSY---------DELNTMLEtrqqtllLPESAADVVVrgdatlLRMLLRN 260
Cdd:COG2972 287 R-----YSLSKGDelvtlEEELELIK-----SYleiqklrfgDRLEVEIE-------IDEELLDLLI------PKLILQP 343
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447134933 261 LVENA--H--RYSPEGTHITIHISADPDAIM-AVEDEGPGIDESKcgkLSEAFVRMDSRYGGIGLGLSIVSRITQLHQG 334
Cdd:COG2972 344 LVENAieHgiEPKEGGGTIRISIRKEGDRLViTVEDNGVGMPEEK---LEKLLEELSSKGEGRGIGLRNVRERLKLYYG 419
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
253-334 |
1.04e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 52.42 E-value: 1.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 253 LLRMLLRNLVENA-HRYSPEGThITIHISADPD-AIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGLGLSIVSRITQ 330
Cdd:cd16943 3 QLNQVLLNLLVNAaQAMEGRGR-ITIRTWAHVDqVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGEGTGLGLSLSYRIIQ 81
|
....
gi 447134933 331 LHQG 334
Cdd:cd16943 82 KHGG 85
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
249-345 |
1.27e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 52.90 E-value: 1.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 249 GDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVEDEGPGIDESKCGKLSEAFVRMD----SRYGGIGLGLS 323
Cdd:cd16947 16 ANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVyIDIWDKGKGISETEKDHVFERLYTLEdsrnSAKQGNGLGLT 95
|
90 100
....*....|....*....|...
gi 447134933 324 IVSRITQLHQGQFFLQNRT-ERT 345
Cdd:cd16947 96 ITKRLAESMGGSIYVNSKPyEKT 118
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
250-334 |
1.94e-08 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 51.72 E-value: 1.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 250 DATLLRMLLRNLVENAHRYSPEGTHIT--IHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDS----RYGGIGLGLS 323
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRciLEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGsstrAHGGTGLGLS 80
|
90
....*....|.
gi 447134933 324 IVSRITQLHQG 334
Cdd:cd16925 81 IVKEFVELHGG 91
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
254-343 |
3.46e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 51.03 E-value: 3.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 254 LRMLLRNLVENAHRYSPEGT-HITIHISADPDAI-MAVEDEGPGIDESKCGKLSEAFV--RMDSRYGGI--GLGLSIVSR 327
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDTgRITVSAMPTGKMVtISVEDEGPGIPQEKLESIFDRFYteRPANEAFGQhsGLGLSISRQ 80
|
90
....*....|....*.
gi 447134933 328 ITQLHQGQFFLQNRTE 343
Cdd:cd16953 81 IIEAHGGISVAENHNQ 96
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
257-335 |
4.89e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 50.47 E-value: 4.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 257 LLRNLVENAHRYSPEGTHITIHIS-ADPDA-IMAVEDEGPGIDESKCGKLSEAFVrmDSRYGGIGLGLSIVSRITQLHQG 334
Cdd:cd16920 8 LVRNGIEAMSEGGCERRELTIRTSpADDRAvTISVKDTGPGIAEEVAGQLFDPFY--TTKSEGLGMGLSICRSIIEAHGG 85
|
.
gi 447134933 335 Q 335
Cdd:cd16920 86 R 86
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
150-338 |
6.12e-08 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 54.31 E-value: 6.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 150 VAHELRTPLSGVRLHLELLSK-----------THNVDVAPLIARLDQMMDSvsqLLQLARVGQSfssgNYQEVkLLEDVI 218
Cdd:COG4192 440 LAHELNQPLNAMSMYLFSAKKaleqenyaqlpTSLDKIEGLIERMDKIIKS---LRQFSRKSDT----PLQPV-DLRQVI 511
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 219 LPSYDELNTMLETRQQTLLLPEsaaDVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVEDEGPGID 297
Cdd:COG4192 512 EQAWELVESRAKPQQITLHIPD---DLMVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLrVAISDNGNGWP 588
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 447134933 298 ESKcgKLSEAFVrmDSRYGGIGLGLSIVSRITQLHQGQFFL 338
Cdd:COG4192 589 LVD--KLFTPFT--TTKEVGLGLGLSICRSIMQQFGGDLYL 625
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
146-340 |
1.21e-07 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 53.58 E-value: 1.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 146 FTADVAHELRTPLSGVRLHLEL-----LSKTHNVDVAPLIARLDQ-MMDSVSQLLQLARVgqsfSSGNYQevklledvIL 219
Cdd:PRK09959 715 FLATMSHEIRTPISSIMGFLELlsgsgLSKEQRVEAISLAYATGQsLLGLIGEILDVDKI----ESGNYQ--------LQ 782
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 220 PSYDELNTMLETR---------QQTLLLPESAA---DVVVRGDATLLRMLLRNLVENAHRYSPEG----THITIHISADP 283
Cdd:PRK09959 783 PQWVDIPTLVQNTchsfgaiaaSKSIALSCSSTfpdHYLVKIDPQAFKQVLSNLLSNALKFTTEGavkiTTSLGHIDDNH 862
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 284 DAI-MAVEDEGPGIDESKCGKLSEAFVRMDS--RYGGIGLGLSIVSRITQLHQGQFFLQN 340
Cdd:PRK09959 863 AVIkMTIMDSGSGLSQEEQQQLFKRYSQTSAgrQQTGSGLGLMICKELIKNMQGDLSLES 922
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
144-201 |
1.28e-07 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 47.98 E-value: 1.28e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 447134933 144 RLFTADVAHELRTPLSGVRLHLELLSKTHNVDVAP-----LIARLDQMMDSVSQLLQLARVGQ 201
Cdd:pfam00512 3 SEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQReyletILRSAERLLRLINDLLDLSRIEA 65
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
144-198 |
1.62e-07 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 47.98 E-value: 1.62e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447134933 144 RLFTADVAHELRTPLSGVRLHLELLSKTHNVD------VAPLIARLDQMMDSVSQLLQLAR 198
Cdd:cd00082 5 GEFLANVSHELRTPLTAIRGALELLEEELLDDeeqreyLERIREEAERLLRLINDLLDLSR 65
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
144-201 |
3.00e-07 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 47.18 E-value: 3.00e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 447134933 144 RLFTADVAHELRTPLSGVRLHLELLSKTHNVD-----VAPLIARLDQMMDSVSQLLQLARVGQ 201
Cdd:smart00388 3 REFLANLSHELRTPLTAIRGYLELLLDTELSEeqreyLETILREAERLLRLINDLLDLSRIEA 65
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
93-335 |
1.29e-06 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 50.02 E-value: 1.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 93 RP---LAELQKELEARTADNLAPiaihSSTLEIESVVSAINQLV-------TRLTTTLdnerlftADVAHELRTPLSGVR 162
Cdd:PRK10815 217 RPieaLAKQVRELEEGEREQLDP----NPPRELTSLVRNLNRLLknereryTKYRTTL-------TDLTHSLKTPLAVLQ 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 163 LHLELL--SKTHNVDVAPLIarldqMMDSVSQLLQL---------ARVGQSFSSGNYQEVKLLEDVILPSydeLNTMLET 231
Cdd:PRK10815 286 STLRSLrsGKQMSVEQAEPI-----MLEQISRISQQigyylhrasMRSEHNLLSRELHSVAPLLDNLTSA---LNKVYQR 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 232 RQQTLLL---PEsaadVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMaVEDEGPGIDESKCGKLSEAF 308
Cdd:PRK10815 358 KGVNITLdisPE----ITFVGEKNDFMEVMGNVLDNACKYCLEFVEISARQTDEHLHIV-VEDDGPGIPESKRELIFDRG 432
|
250 260
....*....|....*....|....*..
gi 447134933 309 VRMDSRYGGIGLGLSIVSRITQLHQGQ 335
Cdd:PRK10815 433 QRADTLRPGQGLGLSVAREITEQYEGK 459
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
145-324 |
3.66e-06 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 48.82 E-value: 3.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 145 LFTADVAHELRTPLSGVRLHLELL-SKTHNVDVapliARLDQMMDSVSQLL----------------QLARVGQSFS--- 204
Cdd:PRK10841 449 MFLATVSHELRTPLYGIIGNLDLLqTKELPKGV----DRLVTAMNNSSSLLlkiisdildfskieseQLKIEPREFSpre 524
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 205 -----SGNYqevklledviLPsydelntmLETRQQTLL--LPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGThITI 277
Cdd:PRK10841 525 vinhiTANY----------LP--------LVVKKRLGLycFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGC-IVL 585
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 447134933 278 HISADPDAI-MAVEDEGPGIDESKCGKLSEAFVRM----DSRYGGIGLGLSI 324
Cdd:PRK10841 586 HVRVDGDYLsFRVRDTGVGIPAKEVVRLFDPFFQVgtgvQRNFQGTGLGLAI 637
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
250-323 |
2.17e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 43.04 E-value: 2.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 250 DATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAI-MAVEDEGPGIDESKCGKLSEAFV-----RMDSRYGGIGLGLS 323
Cdd:cd16948 2 DAKWLSFIIGQIVSNALKYSKQGGKIEIYSETNEQGVvLSIKDFGIGIPEEDLPRVFDKGFtgengRNFQESTGMGLYLV 81
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
146-348 |
2.56e-05 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 46.21 E-value: 2.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 146 FTADVAHELRTPLSGVRLHLEL---LSKTHNV---DVAPLIARLDQMMDSVSQLLQLARVGQSfssgNYQEVKL--LEDV 217
Cdd:PRK13837 453 LASGIAHNFNNILGAILGYAEMalnKLARHSRaarYIDEIISAGARARLIIDQILAFGRKGER----NTKPFDLseLVTE 528
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 218 ILPsydeLNTMLETRQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISA----DPDAI------- 286
Cdd:PRK13837 529 IAP----LLRVSLPPGVELDFDQDQEPAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSRaklrAPKVLshgvlpp 604
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447134933 287 -----MAVEDEGPGIDESKCGKLSEAFvrMDSRYGGIGLGLSIVSRITQLHQGQFFLQNRTERtGTR 348
Cdd:PRK13837 605 gryvlLRVSDTGAGIDEAVLPHIFEPF--FTTRAGGTGLGLATVHGIVSAHAGYIDVQSTVGR-GTR 668
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
146-337 |
2.81e-05 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 46.00 E-value: 2.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 146 FTADVAHELRTPLSGV----RLHLELLSKTHNVDVAPLIARldqmmdSVSQLLQLARVGQSFSsgnyqevKL------LE 215
Cdd:PRK11107 296 FLANMSHELRTPLNGVigftRQTLKTPLTPTQRDYLQTIER------SANNLLAIINDILDFS-------KLeagklvLE 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 216 DVILP---SYDELNTMLETRQQ------TLLLPESAADVVVrGDATLLRMLLRNLVENAHRYSPEGT-HITIHISADPDA 285
Cdd:PRK11107 363 NIPFSlreTLDEVVTLLAHSAHekglelTLNIDPDVPDNVI-GDPLRLQQIITNLVGNAIKFTESGNiDILVELRALSNT 441
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447134933 286 IMAVE----DEGPGIDESKCGKLSEAFVRMDS----RYGGIGLGLSIVSRI-----------TQLHQGQFF 337
Cdd:PRK11107 442 KVQLEvqirDTGIGISERQQSQLFQAFRQADAsisrRHGGTGLGLVITQKLvnemggdisfhSQPNRGSTF 512
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
250-335 |
3.54e-05 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 45.70 E-value: 3.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 250 DATLLRMLLRNLVENAHRYSPEGtHITIHISADPDA--IMAVEDEGPGIDESKCGKLSEAFVRMDSRYG-----GIGLGL 322
Cdd:PRK11091 395 DGTRLRQILWNLISNAVKFTQQG-GVTVRVRYEEGDmlTFEVEDSGIGIPEDELDKIFAMYYQVKDSHGgkpatGTGIGL 473
|
90
....*....|...
gi 447134933 323 SIVSRITQLHQGQ 335
Cdd:PRK11091 474 AVSKRLAQAMGGD 486
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
233-334 |
5.13e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 42.00 E-value: 5.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 233 QQTLLLPESAADVVVRGDATLLrmlLRNLVENAHRYSPEGTHITIHISadpdaimaVEDEGPGIDESKCGKLSEAFVrmD 312
Cdd:cd16918 3 QVFLNLVRNAAQALAGSGGEII---LRTRTQRQVTLGHPRHRLALRVS--------VIDNGPGIPPDLQDTIFYPMV--S 69
|
90 100
....*....|....*....|..
gi 447134933 313 SRYGGIGLGLSIVSRITQLHQG 334
Cdd:cd16918 70 GRENGTGLGLAIAQNIVSQHGG 91
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
257-329 |
5.32e-05 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 42.21 E-value: 5.32e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447134933 257 LLRNLVENAHRYSPEGThITIHISADPDAI-MAVEDEGPGIDESkcgKLSEAFvrmDSRYGGiGLGLSIVSRIT 329
Cdd:COG2172 42 AVTNAVRHAYGGDPDGP-VEVELELDPDGLeIEVRDEGPGFDPE---DLPDPY---STLAEG-GRGLFLIRRLM 107
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
254-343 |
9.47e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 40.90 E-value: 9.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 254 LRMLLRNLVENAHRYSPEGTHITIHISAD---PDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGLGLSIVSRITQ 330
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVENPRIRIAARrlgGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPVGKGTGLGLSISYGIVE 80
|
90
....*....|...
gi 447134933 331 LHQGQFFLQNRTE 343
Cdd:cd16976 81 EHGGRLSVANEEG 93
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
89-141 |
3.16e-03 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 35.30 E-value: 3.16e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 447134933 89 RRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLD 141
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
250-356 |
5.99e-03 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 38.29 E-value: 5.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 250 DATLLRMLLRNLVENAHRYSPEGT----HITIHISADPDAIM-AVEDEGPGIDESKcgkLSEAFVRMDS--RYGGIGLGL 322
Cdd:COG3290 278 SDTDLVTILGNLLDNAIEAVEKLPeeerRVELSIRDDGDELViEVEDSGPGIPEEL---LEKIFERGFStkLGEGRGLGL 354
|
90 100 110
....*....|....*....|....*....|....
gi 447134933 323 SIVSRITQLHQGQFFLQNRtERTGTRAWVLLKKA 356
Cdd:COG3290 355 ALVKQIVEKYGGTIEVESE-EGEGTVFTVRLPKE 387
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
260-340 |
6.28e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 35.73 E-value: 6.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447134933 260 NLVENAH----RYSPEGTHITIHISAD-PDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRyGGIGLGLSIVSRITQLHQG 334
Cdd:cd16915 7 NLIDNALdalaATGAPNKQVEVFLRDEgDDLVIEVRDTGPGIAPELRDKVFERGVSTKGQ-GERGIGLALVRQSVERLGG 85
|
....*.
gi 447134933 335 QFFLQN 340
Cdd:cd16915 86 SITVES 91
|
|
| |
