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Conserved domains on  [gi|447123634|ref|WP_001200890|]
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MULTISPECIES: FUSC family protein [Enterobacteriaceae]

Protein Classification

FUSC family protein( domain architecture ID 11441727)

FUSC family protein containing a fusaric acid resistance protein (FUSC_2) domain; may be involved in membrane transport

Gene Ontology:  GO:0055085|GO:0022857|GO:0005886
TCDB:  2.A.85

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
16-247 9.21e-40

Uncharacterized membrane protein YccC [Function unknown];


:

Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 141.69  E-value: 9.21e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634  16 RHYRIVHGTRVALAFLLTFLIIRLFTIPESTWPLVTMVVIMGPisFWGNVVPRAFERIGGTVLGSILGLIALQLeLISLP 95
Cdd:COG1289   43 DSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQP--SYGATLSRALQRILGTLLGALAGLLLLAL-FPQPL 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634  96 LMLVWCAAAMFLCgWLALGKKPYQGLLIGVTLAIVVGSPTGE---IDTALWRSGDVILGSLLAMLFTG-IWPQRAFIHWR 171
Cdd:COG1289  120 LLLLALALVLGLC-FFALLTRSYAFALAGITAAVVLLFALLGpgvFDVALARVLDTLIGILIALLVSYlLWPRWARRRLR 198
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447123634 172 IQLAKSLTEYNRVYQSAFSP-NLLERPRLESHLQKLLTDAVKMRGLIAPASKETRIPKSI-YEGIQTINRNLVCMLEL 247
Cdd:COG1289  199 ARLARALRANARYLRALLSQgDPADDLALRAARRRLAAALAALEALLQRALSEPPRGRRReLRALLALNHRLLSLLSA 276
 
Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
16-247 9.21e-40

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 141.69  E-value: 9.21e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634  16 RHYRIVHGTRVALAFLLTFLIIRLFTIPESTWPLVTMVVIMGPisFWGNVVPRAFERIGGTVLGSILGLIALQLeLISLP 95
Cdd:COG1289   43 DSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQP--SYGATLSRALQRILGTLLGALAGLLLLAL-FPQPL 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634  96 LMLVWCAAAMFLCgWLALGKKPYQGLLIGVTLAIVVGSPTGE---IDTALWRSGDVILGSLLAMLFTG-IWPQRAFIHWR 171
Cdd:COG1289  120 LLLLALALVLGLC-FFALLTRSYAFALAGITAAVVLLFALLGpgvFDVALARVLDTLIGILIALLVSYlLWPRWARRRLR 198
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447123634 172 IQLAKSLTEYNRVYQSAFSP-NLLERPRLESHLQKLLTDAVKMRGLIAPASKETRIPKSI-YEGIQTINRNLVCMLEL 247
Cdd:COG1289  199 ARLARALRANARYLRALLSQgDPADDLALRAARRRLAAALAALEALLQRALSEPPRGRRReLRALLALNHRLLSLLSA 276
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
32-158 1.26e-12

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 64.19  E-value: 1.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634   32 LTFLIIRLFTIPESTWPLVTMVVIMGPisFWGNVVPRAFERIGGTVLGSILGLIALQleLISLPLMLVWCAAAMFLCGwL 111
Cdd:pfam13515   1 LAALIAELLGLPRGYWAPIAAAIVLQP--TLGATLRRAVQRILGTVLGVLLGLLLLA--LLPGPLQLILVVALLGFLA-E 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 447123634  112 ALGKKPYQGLLIGVTLAIVV----GSPTGEIDTALWRSGDVILGSLLAMLF 158
Cdd:pfam13515  76 YLIGRNYALAQVFVTPLALLlaslAGGGGPPELALLRILDTLIGALIALLV 126
 
Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
16-247 9.21e-40

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 141.69  E-value: 9.21e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634  16 RHYRIVHGTRVALAFLLTFLIIRLFTIPESTWPLVTMVVIMGPisFWGNVVPRAFERIGGTVLGSILGLIALQLeLISLP 95
Cdd:COG1289   43 DSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQP--SYGATLSRALQRILGTLLGALAGLLLLAL-FPQPL 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634  96 LMLVWCAAAMFLCgWLALGKKPYQGLLIGVTLAIVVGSPTGE---IDTALWRSGDVILGSLLAMLFTG-IWPQRAFIHWR 171
Cdd:COG1289  120 LLLLALALVLGLC-FFALLTRSYAFALAGITAAVVLLFALLGpgvFDVALARVLDTLIGILIALLVSYlLWPRWARRRLR 198
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447123634 172 IQLAKSLTEYNRVYQSAFSP-NLLERPRLESHLQKLLTDAVKMRGLIAPASKETRIPKSI-YEGIQTINRNLVCMLEL 247
Cdd:COG1289  199 ARLARALRANARYLRALLSQgDPADDLALRAARRRLAAALAALEALLQRALSEPPRGRRReLRALLALNHRLLSLLSA 276
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
32-158 1.26e-12

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 64.19  E-value: 1.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634   32 LTFLIIRLFTIPESTWPLVTMVVIMGPisFWGNVVPRAFERIGGTVLGSILGLIALQleLISLPLMLVWCAAAMFLCGwL 111
Cdd:pfam13515   1 LAALIAELLGLPRGYWAPIAAAIVLQP--TLGATLRRAVQRILGTVLGVLLGLLLLA--LLPGPLQLILVVALLGFLA-E 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 447123634  112 ALGKKPYQGLLIGVTLAIVV----GSPTGEIDTALWRSGDVILGSLLAMLF 158
Cdd:pfam13515  76 YLIGRNYALAQVFVTPLALLlaslAGGGGPPELALLRILDTLIGALIALLV 126
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
25-224 1.74e-10

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 62.30  E-value: 1.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634   25 RVALAFLLTFLIIRLFTIPESTWPLVTMVVIMGPISfwGNVVPRAFERIGGTVLGSI--LGLIALqleLISLP-LMLVWC 101
Cdd:pfam04632   6 KTFLAAMLALYIALRLELPQPYWAMTTVFIVSQPLS--GAVLSKSFYRLLGTLVGAAaaVLLVAL---FVQAPlLFLLAL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634  102 AAAMFLCGWLAL---GKKPYQGLLIGVTLAIV----VGSPTGEIDTALWRSGDVILGSLLAMLFTGI-WPQRAFIHWRIQ 173
Cdd:pfam04632  81 ALWIGLCLALSLldrNFRSYAFVLAGYTAAIIglpaVADPEAIFDIAVARVSEISLGILCAALVSALvFPRSVGPALRAR 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 447123634  174 LAKSLTEYNRVYQSAFSPNlLERPRLESHLQKLLTDAVKMRGLIAPASKET 224
Cdd:pfam04632 161 LRARLRDALRLAAAALAGA-PGAEAFEAARLRLAADILALEALRSHAAFES 210
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
25-190 6.49e-10

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 58.08  E-value: 6.49e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634  25 RVALAFLLTFLIIRLFTIPESTWPLVTMVVIMGPiSFWGNVVpRAFERIGGTVLGSILGLIALQL---ELISLPLMLVwc 101
Cdd:COG4129   16 KTALAAALAWLIAELLGLPYPFFAAIAAVLCLQP-TVGRSLR-RALERILGVLIGALVGVLFFLLlgyGPWQLGLAVL-- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634 102 aAAMFLCGWLALGkkpyQGLLIGVTLAIVV---GSPTGEIDTALWRSGDVILGSLLAMLFT-GIWPQRAFIHWRIQLAKS 177
Cdd:COG4129   92 -LAILLAVLLKLG----EGIVLAAVTALLVlllGSPDDSLGYALNRLLDTLIGVGVALLVNlLLLPPDPERRLRRAAAEL 166
                        170
                 ....*....|...
gi 447123634 178 LTEYNRVYQSAFS 190
Cdd:COG4129  167 LEELADILRELLR 179
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
13-173 1.69e-03

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 40.35  E-value: 1.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634   13 RVYRHYRIVHGTRVALAFLLTFLIIRLFTIpESTWP----LVTMVVIMGPI-SFWGNVVPRAFERIGGTVLGSILGLIAL 87
Cdd:pfam04632 335 RLARHRDHGAALLNGLRAALAILLAGAFWI-ATGWPsgatAVLLAAIVCSLfATLDNPAPAARQFLRGTLLAALAALLYL 413
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447123634   88 qleLISLPL-----MLVWCAAAMFLCGWLALGKKPY--QGLLIGVTLAIVVG---SPTGEIDTALWRSGDVILGSLLA-M 156
Cdd:pfam04632 414 ---FFVLPHvdgfpLLCLVLAPPLLLGGLLLARPRTagIGLGLAVFFALLLApqnPYTYDFAAFLNSALALLLGVLLAaV 490
                         170
                  ....*....|....*..
gi 447123634  157 LFTGIWPQRAfiHWRIQ 173
Cdd:pfam04632 491 VFRLIRPVSA--EWLAR 505
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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