|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
1-1040 |
0e+00 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 2067.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 1 MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQF 80
Cdd:PRK10503 1 MQVLPPSSTGGPSRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 81 GQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM 160
Cdd:PRK10503 81 GQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 161 TQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSA 240
Cdd:PRK10503 161 TQVEDMVETRVAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 241 NDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESL 320
Cdd:PRK10503 241 NDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 321 PKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMA 400
Cdd:PRK10503 321 PKSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 401 LTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAI 480
Cdd:PRK10503 401 LTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAI 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 481 LISAVVSLTLTPMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKG 560
Cdd:PRK10503 481 LISAVVSLTLTPMMCARMLSQESLRKQNRFSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKG 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 561 FFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKV 640
Cdd:PRK10503 561 FFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKV 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 641 IARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYV 720
Cdd:PRK10503 641 IARLQTAVAKVPGVDLYLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYV 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 721 NVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQ 800
Cdd:PRK10503 721 NVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIATIEQ 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 801 RFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIV 880
Cdd:PRK10503 801 RFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIV 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 881 LGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQA 960
Cdd:PRK10503 881 LGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQA 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 961 CLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFARHEEEA 1040
Cdd:PRK10503 961 CLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYLLFDRLALYTKSRFPRHEEEA 1040
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
13-1024 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 1426.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 93 SSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVA 172
Cdd:NF033617 81 SSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 173 QKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQ 252
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYED 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 253 LIIAYQ-NGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSD 331
Cdd:NF033617 241 LVIKYAdNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 332 RTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDD 411
Cdd:NF033617 321 RTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 412 AIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLT 491
Cdd:NF033617 401 AIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 492 PMMCARMLSQESlrKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQ 571
Cdd:NF033617 481 PMMCSRLLKANE--KPGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIF 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 572 GTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVdGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKV 651
Cdd:NF033617 559 GMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGV-GGNPGDNTGFGIINLKPWDERDVSAQEIIDRLRPKLAKV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 652 PGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLG 731
Cdd:NF033617 638 PGMDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLG 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 732 ISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLD 811
Cdd:NF033617 718 ISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFN 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 812 QFPVTTISFNVPDNYSLGDAVQAIMDTEKTLnLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHP 891
Cdd:NF033617 798 QFNSATLSFNLAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDP 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 892 ITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMT 971
Cdd:NF033617 877 LTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSRREAIYQAAALRLRPILMT 956
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|...
gi 447120619 972 TLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDR 1024
Cdd:NF033617 957 TLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
12-1023 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1200.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 12 PSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSS 91
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 92 QSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLpNPPVYSKVNPADPPIMTLAVTST--AMPMTQVEDMVET 169
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGV-QRPGISVIKTSLGPIMVLAVTSPdgSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 170 RVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEE 249
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAED 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 250 YRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVL 329
Cdd:pfam00873 240 FEKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 330 SDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVV 409
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 410 DDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSL 488
Cdd:pfam00873 400 DDAIVVVENIERVLeENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVAL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 489 TLTPMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNG 568
Cdd:pfam00873 480 TLTPALCATLLKPRREPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 569 IIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGV--DGTNPSLNSARLQINLKPLDER---DDRVQKVIAR 643
Cdd:pfam00873 560 VFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFafSGDNNGPNSGDAFISLKPWKERpgpEKSVQALIER 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 644 LQTAVDKVPGVDLFLQPTQDLTID--TQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVN 721
Cdd:pfam00873 640 LRKALKQIPGANVFLFQPIQLRGLgtISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQLQVN 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 722 VDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQR 801
Cdd:pfam00873 720 IDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFAKIEWG 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 802 FAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVL 881
Cdd:pfam00873 800 YGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLVVFLVL 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 882 GILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQAC 961
Cdd:pfam00873 880 AALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKSLEEAILEAC 959
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 447120619 962 LLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFD 1023
Cdd:pfam00873 960 RLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
13-1028 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1134.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
Cdd:COG0841 4 SRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITST 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 93 SSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLpNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVA 172
Cdd:COG0841 84 SSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDV-EPPGVTKVNPSDFPVMVLALSSDDLDELELSDYAERNIK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 173 QKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQ 252
Cdd:COG0841 163 DRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEEFEN 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 253 LIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDR 332
Cdd:COG0841 243 IVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTIVYDQ 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 333 TTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDA 412
Cdd:COG0841 323 SEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVVDDA 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 413 IVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTP 492
Cdd:COG0841 403 IVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALTLTP 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 493 MMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQG 572
Cdd:COG0841 483 ALCARLLKPHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIV 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 573 TLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVP 652
Cdd:COG0841 563 SVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDRSADEIIARLREKLAKIP 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 653 GVDLFLQPTQDltiDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGI 732
Cdd:COG0841 643 GARVFVFQPPA---GGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAALGV 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 733 SMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQ 812
Cdd:COG0841 720 TVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTGPSSINRYNG 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 813 FPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPI 892
Cdd:COG0841 800 QRSVTVSANLAPGVSLGEALAAIEELAAELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLAAQFESFIQPL 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 893 TILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALaAEREQGMSPREAIYQACLLRFRPILMTT 972
Cdd:COG0841 880 IILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFAN-QLREEGMSLREAILEAARLRLRPILMTS 958
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
gi 447120619 973 LAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALW 1028
Cdd:COG0841 959 LATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRR 1014
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
15-1025 |
0e+00 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 1060.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 15 LFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSS 94
Cdd:PRK10614 6 LFIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 95 GGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQK 174
Cdd:PRK10614 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGQLYDFASTQLAQT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 175 ISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLI 254
Cdd:PRK10614 166 ISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLI 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 255 IAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTT 334
Cdd:PRK10614 246 IHYNNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIAQDRSP 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 335 NIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIV 414
Cdd:PRK10614 326 TIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIV 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 415 VIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMM 494
Cdd:PRK10614 406 VLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLTLTPMM 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 495 CARMLSQESLRKQNRfSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTL 574
Cdd:PRK10614 486 CAWLLKSSKPREQKR-LRGFGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFPEQDTGRLMGFI 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 575 QAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTnpslNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGV 654
Cdd:PRK10614 565 QADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRV----NSGMMFITLKPLSERSETAQQVIDRLRVKLAKEPGA 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 655 DLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISM 734
Cdd:PRK10614 641 NLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKALAALPELADVNSDQQDKGAEMALTYDRDTMARLGIDV 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 735 ADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFP 814
Cdd:PRK10614 721 QAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSA 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 815 VTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITI 894
Cdd:PRK10614 801 ASTISFNLPTGKSLSDASAAIERAMTQLGVPSTVRGSFAGTAQVFQETMNSQLILILAAIATVYIVLGILYESYVHPLTI 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 895 LSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTTLA 974
Cdd:PRK10614 881 LSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGNLTAQEAIFQACLLRFRPIMMTTLA 960
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|.
gi 447120619 975 ALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRL 1025
Cdd:PRK10614 961 ALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL 1011
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
13-1025 |
7.30e-174 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 536.23 E-value: 7.30e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
Cdd:TIGR00915 2 AKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 93 SSG-GASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVysKVNPA-DPPIMTLAVTSTAMPMTQVE--DMVE 168
Cdd:TIGR00915 82 SDSdGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGV--RVEKAsSNFLMVIGLVSDDGSMTKEDlsDYAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 169 TRVAQKISQISGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDG-PSRA-----VTLSAND 242
Cdd:TIGR00915 160 SNMVDPLSRLEGVGDVQLFGSQY-AMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGlPAVPgqqlnATIIAQT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 243 QMQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLP 321
Cdd:TIGR00915 239 RLQTPEQFENILLkVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 322 KSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMAL 401
Cdd:TIGR00915 319 QGMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAM 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 402 TIATGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAI 480
Cdd:TIGR00915 399 VLAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAM 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 481 LISAVVSLTLTPMMCARML----SQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVF 556
Cdd:TIGR00915 479 ALSVLVALILTPALCATMLkpieKGEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVR 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 557 IPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAvQSLTSFVGVDGTNPS---LNSARLQINLKPLDER 633
Cdd:TIGR00915 559 LPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEK-ANVESVFTVNGFSFAgrgQNMGMAFIRLKDWEER 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 634 D---DRVQKVIARLQTAVDKVPgvDLFLQPTQDLTIDTQVSRTQYQFTLQA---TSLDALSTWVPQLMEKLQQLPQLSDV 707
Cdd:TIGR00915 638 TgkeNSVFAIAGRATGHFMQIK--DAMVIAFVPPAILELGNATGFDFFLQDragLGHEALLQARNQLLGLAAQNPALTRV 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 708 SSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDG 787
Cdd:TIGR00915 716 RPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASG 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 788 GVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKtlNLPVDITTQFQGSTLAFQSALGSTV 867
Cdd:TIGR00915 796 EMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQ--KLPPGFGFSWTGMSYEERLSGSQAP 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 868 WLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFAlAAER 947
Cdd:TIGR00915 874 ALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFA-KELM 952
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447120619 948 EQGMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRL 1025
Cdd:TIGR00915 953 AQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRL 1030
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
14-1024 |
1.13e-142 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 453.72 E-value: 1.13e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 14 RLFIMrpvattLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQS 93
Cdd:COG3696 13 RLLVL------LLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 94 SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDlpnppvyskVNPA-DPP------IMTLAVTSTAMPMTQVE-- 164
Cdd:COG3696 87 RFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAG---------VTPElGPIstglgeIYQYTLESDPGKYSLMElr 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 165 DMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQM 244
Cdd:COG3696 158 TLQDWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 245 QSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSwLGA--WANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPK 322
Cdd:COG3696 238 RSLEDIENIVVKTRNGTPVLLRDVAEVRIGPAPR-RGAatLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPE 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 323 SVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALT 402
Cdd:COG3696 317 GVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 403 IATGFVVDDAIVVIENISRYIEK------GEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITL 476
Cdd:COG3696 397 IDFGIIVDGAVVMVENILRRLEEnraagtPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTV 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 477 AVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRasekmfdRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVF 556
Cdd:COG3696 477 IFALLGALLLSLTLVPVLASLLLRGKVPEKENPLVR-------WLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPR 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 557 IPKGFFPVQDNG--IIQGTLqaPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGV--DGTNP-SLNSARLQINLKPLD 631
Cdd:COG3696 550 LGSEFLPELDEGdlLVMATL--PPGISLEESVELGQQVERILKSFPEVESVVSRTGRaeDATDPmGVNMSETFVILKPRS 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 632 E-RDDR-VQKVIARLQTAVDKVPGVDL-FLQPTQDlTIDTQVS--RTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSD 706
Cdd:COG3696 628 EwRSGRtKEELIAEMREALEQIPGVNFnFSQPIQM-RVDELLSgvRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAAD 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 707 VSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQY--RVVLEHNTENTPglAALDTIRLTS 784
Cdd:COG3696 707 VQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFdiVVRLPEELRDDP--EAIRNLPIPT 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 785 SDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVpDNYSLGDAVQAIMDT-EKTLNLPVDITTQFQGSTLAFQSAL 863
Cdd:COG3696 785 PSGAQVPLSQVADIEVVEGPNQISRENGRRRIVVQANV-RGRDLGSFVAEAQAKvAEQVKLPPGYYIEWGGQFENLQRAT 863
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 864 GSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSEL--------------DVIaiigiillig 929
Cdd:COG3696 864 ARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLsvsagvgfialfgvAVL---------- 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 930 ivkkNAIMMIDFALAAeREQGMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQV 1009
Cdd:COG3696 934 ----NGVVLVSYINQL-RAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTL 1008
|
1050
....*....|....*
gi 447120619 1010 LTLFTTPVIYLLFDR 1024
Cdd:COG3696 1009 LTLLVLPALYLLFGR 1023
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
15-1024 |
3.23e-137 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 438.88 E-value: 3.23e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 15 LFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSS 94
Cdd:PRK09579 6 PFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 95 GGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPpVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQK 174
Cdd:PRK09579 86 QNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDP-VLSKEAADASALMYISFYSEEMSNPQITDYLSRVIQPK 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 175 ISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLI 254
Cdd:PRK09579 165 LATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEAFAAIP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 255 IAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTT 334
Cdd:PRK09579 245 VKTSGDSRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIAYDATL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 335 NIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIV 414
Cdd:PRK09579 325 FIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDAIV 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 415 VIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMM 494
Cdd:PRK09579 405 VVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALTLSPMM 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 495 CARMLSQEslRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTL 574
Cdd:PRK09579 485 CALLLRHE--ENPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSELAPEEDQGIIFMMS 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 575 QAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSarlqINLKPLDERDDRVQKVIARLQTAVDKVPGV 654
Cdd:PRK09579 563 SSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQSGIGG----FLLKPWNERERTQMELLPLVQAKLEEIPGL 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 655 DLFLQPTQDLTIDTQvsRTQYQFTLQ-ATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQ-DKGLVAyVNVDRDSASRLGI 732
Cdd:PRK09579 639 QIFGFNLPSLPGTGE--GLPFQFVINtANDYESLLQVAQRVKQRAQESGKFAFLDIDLAfDKPEVV-VDIDRAKAAQMGV 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 733 SMADVDNALYNAFGQRLISTIYTQANQYRVV--LEHNTENTPGLaaLDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHL 810
Cdd:PRK09579 716 SMQDLGGTLATLLGEGEINRFTIDGRSYKVIaqVERPYRDNPGW--LNNYYVKNEQGQLLPLSTLITLSDRARPRQLNQF 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 811 DQFPVTTISfNVPdNYSLGDAVQAIMDTEKTlNLPVDITTQFQGSTLAFQSAlGSTVWLIVAAVVAM-YIVLGILYESFI 889
Cdd:PRK09579 794 QQLNSAIIS-GFP-IVSMGEAIETVQQIARE-EAPEGFAFDYAGASRQYVQE-GSALWVTFGLALAIiFLVLAAQFESFR 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 890 HPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPIL 969
Cdd:PRK09579 870 DPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLSRREAIEEAAAIRLRPVL 949
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*
gi 447120619 970 MTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDR 1024
Cdd:PRK09579 950 MTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAK 1004
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
13-1024 |
5.02e-128 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 415.00 E-value: 5.02e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
Cdd:PRK10555 2 ANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 93 SSG-GASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKvNPADPPIMTLAVTST--AMPMTQVEDMVET 169
Cdd:PRK10555 82 SSGtGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVR-KTGDTNILTIAFVSTdgSMDKQDIADYVAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 170 RVAQKISQISGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDG----PSRAV--TLSANDQ 243
Cdd:PRK10555 161 NIQDPLSRVNGVGDIDAYGSQY-SMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGtpsvDKQALnaTINAQSL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 244 MQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPK 322
Cdd:PRK10555 240 LQTPEQFRDITLrVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPH 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 323 SVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALT 402
Cdd:PRK10555 320 GLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 403 IATGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAIL 481
Cdd:PRK10555 400 LAIGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMV 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 482 ISAVVSLTLTPMMCARML---SQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHP--WLTLSVALSTLLLsvllWVF 556
Cdd:PRK10555 480 LSVLVAMILTPALCATLLkplKKGEHHGQKGFFGWFNRMFNRNAERYEKGVAKILHRSlrWILIYVLLLGGMV----FLF 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 557 I--PKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPA--VQSLTSFVGVDGTNPSLNSARLQINLKPLDE 632
Cdd:PRK10555 556 LrlPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKdnVMSVFATVGSGPGGNGQNVARMFIRLKDWDE 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 633 RDDRVQK---VIARLQTAVDKVPGVDLFlqPTQDLTIDTQVSRTQYQFTLQ---ATSLDALSTWVPQLMEKLQQLPQLSD 706
Cdd:PRK10555 636 RDSKTGTsfaIIERATKAFNKIKEARVI--ASSPPAISGLGSSAGFDMELQdhaGAGHDALMAARNQLLALAAKNPELTR 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 707 VSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLIS---------TIYTQAN-QYRVVlehntentPGLAA 776
Cdd:PRK10555 714 VRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNdfmdrgrvkKVYVQAAaPYRML--------PDDIN 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 777 LDTIRltSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAvqaiMDTEKTL--NLPVDITTQFQG 854
Cdd:PRK10555 786 LWYVR--NKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTA----MDIMESLvkQLPNGFGLEWTA 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 855 STLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKN 934
Cdd:PRK10555 860 MSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKN 939
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 935 AIMMIDFAlAAEREQGMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFT 1014
Cdd:PRK10555 940 AILIVEFA-NEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFF 1018
|
1050
....*....|
gi 447120619 1015 TPVIYLLFDR 1024
Cdd:PRK10555 1019 VPLFFVLVRR 1028
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
13-1025 |
7.25e-126 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 409.24 E-value: 7.25e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
Cdd:PRK09577 2 ARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSAT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 93 SSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKvNPADPPIMTLAVTSTAMPMTQVE--DMVETR 170
Cdd:PRK09577 82 SSAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVE-KAADNIQLIVSLTSDDGRLTGVElgEYASAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 171 VAQKISQISGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSL------DGPSRAVTLSANDQM 244
Cdd:PRK09577 161 VLQALRRVEGVGKVQFWGAEY-AMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIgrsavpDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 245 QSAEEYRQLIIAYQ-NGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKS 323
Cdd:PRK09577 240 KTPEDFGAIALRARaDGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 324 VKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTI 403
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 404 ATGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILI 482
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMvEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 483 SAVVSLTLTPMMCARMLSQESLRKQNR--FSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKG 560
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPVDGDHHEKrgFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPTA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 561 FFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVD--GTNPslNSARLQINLKPLDER---DD 635
Cdd:PRK09577 560 FLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNlyGEGP--NGGMIFVTLKDWKERkaaRD 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 636 RVQKVIARLQTAVDKVPGVDLF---LQPTQDLTidtqvSRTQYQFTLQ---ATSLDALSTWVPQLMEKLQQLPQLSDVSS 709
Cdd:PRK09577 638 HVQAIVARINERFAGTPNTTVFamnSPALPDLG-----STSGFDFRLQdrgGLGYAAFVAAREQLLAEGAKDPALTDLMF 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 710 DWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGV 789
Cdd:PRK09577 713 AGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEM 792
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 790 VPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTlnLPVDITTQFQGSTLAFQSALGSTVWL 869
Cdd:PRK09577 793 VPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAAT--LPAGIGYAWSGQSFEERLSGAQAPML 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 870 IVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFA--LAAer 947
Cdd:PRK09577 871 FALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAkdLVA-- 948
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447120619 948 eQGMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRL 1025
Cdd:PRK09577 949 -QRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGRL 1025
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
13-1039 |
2.57e-115 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 381.17 E-value: 2.57e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
Cdd:PRK15127 2 PNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 93 S-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVySKVNPADPPIMTLAVTSTAMPMTQ--VEDMVET 169
Cdd:PRK15127 82 SdSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGV-SVEKSSSSFLMVVGVINTDGTMTQedISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 170 RVAQKISQISGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDG--PSRAVTLSAN----DQ 243
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQY-AMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGtpPVKGQQLNASiiaqTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 244 MQSAEEYRQLIIAY-QNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPK 322
Cdd:PRK15127 240 LTSTEEFGKILLKVnQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 323 SVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALT 402
Cdd:PRK15127 320 GLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 403 IATGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAIL 481
Cdd:PRK15127 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 482 ISAVVSLTLTPMMCARMLSQ----ESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFI 557
Cdd:PRK15127 480 LSVLVALILTPALCATMLKPiakgDHGEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRL 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 558 PKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVIL--QDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDER-- 633
Cdd:PRK15127 560 PSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLtkEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRpg 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 634 -DDRVQKVIARLQTAVDKVPgvDLFLQPTQDLTIDTQVSRTQYQFTL--QAT-SLDALSTWVPQLMEKLQQLPQ-LSDVS 708
Cdd:PRK15127 640 eENKVEAITMRATRAFSQIK--DAMVFAFNLPAIVELGTATGFDFELidQAGlGHEKLTQARNQLLGEAAKHPDmLVGVR 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 709 SDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGG 788
Cdd:PRK15127 718 PNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQ 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 789 VVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVqAIMDtEKTLNLPVDITTQFQGstLAFQSALG--ST 866
Cdd:PRK15127 798 MVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAM-ELME-ELASKLPTGVGYDWTG--MSYQERLSgnQA 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 867 VWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAE 946
Cdd:PRK15127 874 PALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLM 953
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 947 REQGMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRla 1026
Cdd:PRK15127 954 DKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRR-- 1031
|
1050
....*....|...
gi 447120619 1027 lwtksRFARHEEE 1039
Cdd:PRK15127 1032 -----RFSRKNED 1039
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
25-1024 |
1.21e-89 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 310.15 E-value: 1.21e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 25 LLMVAILLAGIIG---YRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVIT 101
Cdd:TIGR00914 15 LVLLATLVMAILGiwsYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSRYGLSQVT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 102 LQFQLTLPLDVAEQEVQAAINAATNLLPSDlpnppvyskVNPADPPIMT----------LAVTSTAMPMTQVEDMVETRV 171
Cdd:TIGR00914 95 VIFKDGTDLYFARQLVNERLQQARDNLPEG---------VSPEMGPISTglgeiflytvEAEEGARKKDGGAYTLTDLRT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 172 AQ------KISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQ 245
Cdd:TIGR00914 166 IQdwiirpQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQVQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 246 SAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVK 325
Cdd:TIGR00914 246 SMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPEGVE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 326 VTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALtiAT 405
Cdd:TIGR00914 326 IVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGAL--DF 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 406 GFVVDDAIVVIENISRYIEKGEKPLAAALK----------GAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAIT 475
Cdd:TIGR00914 404 GLIVDGAVVIVENAHRRLAEAQHHHGRQLTlkerlhevfaASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPMAFT 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 476 LAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRasekmfdRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWV 555
Cdd:TIGR00914 484 VVLALAGAMILSLTFVPAAVALFIRGKVAEKENRLMR-------VLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIAS 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 556 FIPKGFFPVQDNG-IIQGTLQAPqSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVD--GTNPS-LNSARLQINLKPLD 631
Cdd:TIGR00914 557 RVGGEFIPSLNEGdLAYQALRIP-GTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAeiATDPMpPNASDTYIILKPES 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 632 ERDDRVQ---KVIARLQTAVDKVPG-VDLFLQPTQdLTIDTQVS--RTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLS 705
Cdd:TIGR00914 636 QWPEGKKtkeDLIEEIQEATVRIPGnNYEFTQPIQ-MRFNELISgvRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAA 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 706 DVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVL---EHNTENTPGLAALdTIRL 782
Cdd:TIGR00914 715 DVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIrlpESLRESPQALRQL-PIPL 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 783 TSSDGGV---VPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNySLG----DAVQAIMDTEKtlnLPVDITTQFQGS 855
Cdd:TIGR00914 794 PLSEDARkqfIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGR-DLGsfvdDAKKAIAEQVK---LPPGYWITWGGQ 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 856 TLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNA 935
Cdd:TIGR00914 870 FEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNG 949
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 936 IMMIDFaLAAEREQGMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTT 1015
Cdd:TIGR00914 950 LVMISF-IRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVL 1028
|
....*....
gi 447120619 1016 PVIYLLFDR 1024
Cdd:TIGR00914 1029 PALYRLVHR 1037
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
289-543 |
6.30e-17 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 86.07 E-value: 6.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 289 AIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSD---RTTNIRASVDDTQFELMMAIALVVMIIYLFLRNI 365
Cdd:COG1033 163 LIVVTLDPDPLSSDLDRKEVVAEIRAIIAKYEDPGVEVYLTGFpvlRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSL 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 366 PATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTII 445
Cdd:COG1033 243 RGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVL 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 446 SLTFSLIAVLIPLLFMgDIvgRLFREFAITLAVAILISAVVSLTLTPMmcarMLSQESLRKQNRFSRASEKMFDRIIAAY 525
Cdd:COG1033 323 LTSLTTAIGFLSLLFS-DI--PPIRDFGIVAAIGVLLAFLTSLTLLPA----LLSLLPRPKPKTRRLKKPPELGRLLAKL 395
|
250
....*....|....*...
gi 447120619 526 GRglaKVLNHPWLTLSVA 543
Cdd:COG1033 396 AR---FVLRRPKVILVVA 410
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
290-492 |
2.64e-15 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 80.67 E-value: 2.64e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 290 IVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFE-LMMAIALVVMIIYLFLRNIPAT 368
Cdd:COG1033 553 VTVRLKDLDSEEIKALVEEVRAFLAENFPPDGVEVTLTGSAVLFAAINESVIESQIRsLLLALLLIFLLLLLAFRSLRLG 632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 369 IIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLT 448
Cdd:COG1033 633 LISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTS 712
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 447120619 449 FSLIAVLIPLLFmGDIVGrlFREFAITLAVAILISAVVSLTLTP 492
Cdd:COG1033 713 LTLAAGFGVLLF-SSFPP--LADFGLLLALGLLVALLAALLLLP 753
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
319-506 |
2.07e-07 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 54.74 E-value: 2.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 319 SLPksVKVTVLSDRT-------TNIRASVddtqFELMMAIALVVMIIYLFLRnipatiIPGVAVPLSLIG----TFAVMV 387
Cdd:COG0342 248 ALP--APLEIVEERTvgptlgaDSIEKGL----IAGLIGLLLVALFMLLYYR------LPGLVANIALALnvvlLLGVLS 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 388 FLDFsinNLTL-----MALTIATGfvVDDAIVVIENISRYIEKGeKPLAAALkgagEIGF-----TIIS--LTfSLIAVL 455
Cdd:COG0342 316 LLGA---TLTLpgiagIILTIGMA--VDANVLIFERIREELRAG-RSLRAAI----EAGFkrafsTILDanVT-TLIAAV 384
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 447120619 456 IpLLFMGdiVGRLfREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRK 506
Cdd:COG0342 385 V-LFVLG--TGPV-KGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKK 431
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
303-496 |
2.76e-07 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 53.83 E-value: 2.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 303 ISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVD-DTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIG 381
Cdd:pfam03176 103 DESVAAVRDAVEQAPPPEGLKAYLTGPAATVADLRDAGDrDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGA 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 382 TFAVMVFL----DFSINNLT---LMALTIATGfvVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIislTFSLIAV 454
Cdd:pfam03176 183 AQGLVAILahilGIGLSTFAlnlLVVLLIAVG--TDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVV---TAAGLTV 257
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 447120619 455 LIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCA 496
Cdd:pfam03176 258 AIAMLALSFARLPVFAQVGPTIAIGVLVDVLAALTLLPALLA 299
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
283-488 |
1.18e-06 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 49.95 E-value: 1.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 283 WANKEQAIVMNVQRQPGANIIStADSIRQMLPQLTESLpksvkvtvlsdrttnIRASVddtqfeLMMAIALVVMIIYLFL 362
Cdd:TIGR00916 9 FADFAANIGKPAIVLDNAKVIS-APVVGTVGPTLGGEL---------------IKAGI------IALLIGLVLVLLYMLL 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 363 RNIPATIIPGVAVPLS-LIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGE-KPLAAALkgagEI 440
Cdd:TIGR00916 67 RYEWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFDRIREELRKYKgRTFREAI----NL 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 447120619 441 GF------TIISLTFSLIAVLIPLLFMGDIVgrlfREFAITLAVAILISAVVSL 488
Cdd:TIGR00916 143 GInqtlsrIIDTNVTTLLAVLALYVFGGGAI----KGFALTLGIGVIAGTYSSI 192
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
305-543 |
1.95e-06 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 52.08 E-value: 1.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 305 TADSIRQMLPQLTESLPKSVKVTV----LSDRTTNIRASVDDTQFELM-MAIALVVMIIylFLRNIPATIIPGVAVPLSL 379
Cdd:COG2409 130 AAEAVDALRDAVAAAPAPGLTVYVtgpaALAADLNEAFEEDLGRAELItLPVALVVLLL--VFRSLVAALLPLLTAGLAV 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 380 IGTFAVMVFL-------DFSINNLTLMALTIATgfvvDDAIVVIeniSRY---IEKGEKPLAA---ALKGAGEI----GF 442
Cdd:COG2409 208 GVALGLLALLaaftdvsSFAPNLLTMLGLGVGI----DYALFLV---SRYreeLRAGEDREEAvarAVATAGRAvlfsGL 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 443 TIIsltfslIAvLIPLLFMGDivgRLFREFAITLAVAILISAVVSLTLTPMMCA----RMLSQeSLRKQNRFSRASEKMF 518
Cdd:COG2409 281 TVA------IA-LLGLLLAGL---PFLRSMGPAAAIGVAVAVLAALTLLPALLAllgrRVFWP-RRPRRRRAAAPESGFW 349
|
250 260
....*....|....*....|....*
gi 447120619 519 DRIIAAygrglakVLNHPWLTLSVA 543
Cdd:COG2409 350 RRLARA-------VVRRPVPVLVAA 367
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
319-514 |
9.14e-06 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 49.45 E-value: 9.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 319 SLPksVKVTVLSDRT-------TNIRASVddtqFELMMAIALVV--MIIY--LFlrnipaTIIPGVAVPLSLIGTFAVMV 387
Cdd:PRK05812 274 ALP--APLEIVEERTigpslgaDSIRAGL----IAGLIGLALVLlfMILYyrLF------GLIANIALVANLVLILAVLS 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 388 FLDFSinnLTL-----MALTIatGFVVDdAIVVI-ENISRYIEKGEKPLAAAlkgagEIGF-----TIIS--LTfSLIAV 454
Cdd:PRK05812 342 LLGAT---LTLpgiagIVLTI--GMAVD-ANVLIfERIREELREGRSLRSAI-----EAGFkrafsTILDsnIT-TLIAA 409
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 455 LIpLLFMGdiVGrLFREFAITLAVAILISAVVSLTLTpmmcaRMLSQESLRKQNRFSRAS 514
Cdd:PRK05812 410 II-LYALG--TG-PVKGFAVTLGIGILTSMFTAITVT-----RALVNLLYGRRKRLKKLS 460
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
305-491 |
2.04e-05 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 48.05 E-value: 2.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 305 TADSIRQMLPQL-TESLPksVKVTVLSDRTT-------NIRASVddtqfeLMMAIALVVMIIYLFLRNIPATIIPGVAVP 376
Cdd:TIGR01129 210 TAEEANDLALVLrSGALP--APLQILEERTIgpslgadSIEAGI------KAGLIGLVLVLVFMILYYRLFGLIAAIALV 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 377 LSLIGTFAVMVFLDFSinnLTL-----MALTIatGFVVDDAIVVIENISRYIEKGEKPLAAAlkgagEIGF-----TIIS 446
Cdd:TIGR01129 282 INIVLILAILSAFGAT---LTLpgiagLILTI--GMAVDANVLIYERIKEELRLGKSVRQAI-----EAGFerafsTIFD 351
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 447120619 447 --LTfSLIAVLIPLLF-MGDIVGrlfreFAITLAVAILISAVVSLTLT 491
Cdd:TIGR01129 352 anIT-TLIAALILYVFgTGPVKG-----FAVTLAIGIIASLFTALVFT 393
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
343-491 |
2.09e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 45.62 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 343 TQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENIsry 422
Cdd:PRK12911 909 TQGIISVCLGLAVLIVLMSVYYRFGGVIASGAVLLNLLLIWAALQYLDAPLTLSGLAGIVLAMGMAVDANVLVFERI--- 985
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447120619 423 ieKGEKPLAAALKGAGEIG----FTII---SLTFSLIAVLIPLLFMGDIVGrlfreFAITLAVAILISAVVSLTLT 491
Cdd:PRK12911 986 --REEYLLSRSLSESVEAGykkaFSAIfdsNLTTILASALLLMLDTGPIKG-----FALTLIIGIFSSMFTALFMT 1054
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
319-511 |
1.37e-03 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 42.53 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 319 SLPksVKVTVLSDRTTN-------IRASVddtqfeLMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDF 391
Cdd:PRK13024 243 ALP--APLKIIESRSVGptlgqdaIDAGI------IAGIIGFALIFLFMLVYYGLPGLIANIALLLYIFLTLGALSSLGA 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 392 SINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTII--SLTfSLIAVLIplLFM---GDIvg 466
Cdd:PRK13024 315 VLTLPGIAGLVLGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILdsNIT-TLIAAAI--LFFfgtGPV-- 389
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 447120619 467 rlfREFAITLAVAILISAVVSLTLTpmmcaRMLSQESLRKQNRFS 511
Cdd:PRK13024 390 ---KGFATTLIIGILASLFTAVFLT-----RLLLELLVKRGDKKP 426
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
824-1026 |
2.47e-03 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 41.77 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 824 DNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLpTAGV 903
Cdd:COG1033 178 DRKEVVAEIRAIIAKYEDPGVEVYLTGFPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVV-LLAV 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 904 GALLALL-IAGSELDVIAiigiilligivkkNAIMMIDFALA------------AEREQGMSPREAIYQACLLRFRPILM 970
Cdd:COG1033 257 IWTLGLMgLLGIPLSPLT-------------ILVPPLLLAIGidygihllnryrEERRKGLDKREALREALRKLGPPVLL 323
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447120619 971 TTLaallgalplmlSTGVG------AELR--RPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLA 1026
Cdd:COG1033 324 TSL-----------TTAIGflsllfSDIPpiRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPK 376
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
347-543 |
3.80e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 41.36 E-value: 3.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 347 LMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKG 426
Cdd:TIGR00921 199 MAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIG 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447120619 427 EKPLAAALKGAGEIGFTIIsltFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPmmcARMLSQESLRK 506
Cdd:TIGR00921 279 RAKGEAIVTAVRRTGRAVL---IALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLP---ALLQSIDIGRE 352
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 447120619 507 QNRFSRASEKmfdRIIAAYGRGLAKVLN----HPWLTLSVA 543
Cdd:TIGR00921 353 KVKKEIIAIG---GKSSEIEEELSKVLSitvrHPVPALVAA 390
|
|
| |
