|
Name |
Accession |
Description |
Interval |
E-value |
| COG5001 |
COG5001 |
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ... |
10-686 |
0e+00 |
|
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];
Pssm-ID: 444025 [Multi-domain] Cd Length: 678 Bit Score: 621.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 10 LVAVSFAVAIFASYTALNMAGRVAGSARSNARIWLIGGGFALGVGIWAMHFVGMLAMDHAMNMRFDPFLTGLSMLIAIGS 89
Cdd:COG5001 1 LLALAALLLLLLALLLALLLLALLLLALLLAALLALALLLLLLLLLLALLLAALLLLALLALLALLLLAAALLALALAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 90 SLFALWLVSAEKLRLRRLLPGALVMGLGISAMHYTGMAALQFASIIVWNSAWVALSIIIALLAScGALWLTFRLRHEGTD 169
Cdd:COG5001 81 LLAALLAALLLLLLLLLALLVLLLLLLLLLALLALLAALLARALAALLLAAASAALLAAALGAA-LLAALALALLLALAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 170 VALRRAGAAVLMGIAIAGMHYAGMKAAHFPQNWPMEHRGVDSNWLAVLVSVVALTILGITLLVSLFDARLQARTALLASS 249
Cdd:COG5001 160 ALLALLLLLLLALLLLLLLLLLLALLLLLLLALLLRLLLLLRGGRLLRLALRLLLGLLLLGLLLLLLLVAVLAIARLITE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 250 LAQANQELAQLALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQP 329
Cdd:COG5001 240 RKRAEERLRHLAYHDPLTGLPNRRLFLDRLEQALARARRSGRRLALLFIDLDRFKEINDTLGHAAGDELLREVARRLRAC 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 330 LSGQFTLARIGGDEF-VLLAEVSAPDEAASLASALVHSIDAPFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMY 408
Cdd:COG5001 320 LREGDTVARLGGDEFaVLLPDLDDPEDAEAVAERILAALAEPFELDGHELYVSASIGIALYPDDGADAEELLRNADLAMY 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 409 HTKHTGRNGYHFFQPSMNMLAQTQLQLMNDLWLALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPL 488
Cdd:COG5001 400 RAKAAGRNRYRFFDPEMDERARERLELEADLRRALERGELELHYQPQVDLATGRIVGAEALLRWQHPERGLVSPAEFIPL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 489 AEKTGLIVTIGSWVIDEACRQLREWHLQGYALWSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKP 568
Cdd:COG5001 480 AEETGLIVPLGEWVLREACRQLAAWQDAGLPDLRVAVNLSARQLRDPDLVDRVRRALAETGLPPSRLELEITESALLEDP 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 569 EQSVAILTRLTEMGVKASIDDFGTGYSSLLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVE 648
Cdd:COG5001 560 EEALETLRALRALGVRIALDDFGTGYSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEVVAEGVE 639
|
650 660 670
....*....|....*....|....*....|....*...
gi 447068068 649 NETQQQFLTQLGCHTLQGFLLGKPRTAEEIARDIRDPA 686
Cdd:COG5001 640 TEEQLEFLRELGCDYAQGYLFSRPLPAEELEALLRARA 677
|
|
| PRK10060 |
PRK10060 |
cyclic di-GMP phosphodiesterase; |
253-680 |
5.21e-109 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 236645 [Multi-domain] Cd Length: 663 Bit Score: 344.74 E-value: 5.21e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 253 ANQELAQLALHDTLTRLPNRVLLEDRLEQAISKANRESTsfALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSG 332
Cdd:PRK10060 229 AQERLRILANTDSITGLPNRNAIQELIDHAINAADNNQV--GIVYLDLDNFKKVNDAYGHMFGDQLLQDVSLAILSCLEE 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 333 QFTLARIGGDEFVLLAEVSAPDEAASLASALVHSIDAPFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMYHTKH 412
Cdd:PRK10060 307 DQTLARLGGDEFLVLASHTSQAALEAMASRILTRLRLPFRIGLIEVYTGCSIGIALAPEHGDDSESLIRSADTAMYTAKE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 413 TGRNGYHFFQPSMNMLAQTQLQLMNDLWLALERQELRLVYQPKFQApAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKT 492
Cdd:PRK10060 387 GGRGQFCVFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITW-RGEVRSLEALVRWQSPERGLIPPLEFISYAEES 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 493 GLIVTIGSWVIDEACRQLREWHLQGYALwSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKPEQSV 572
Cdd:PRK10060 466 GLIVPLGRWVMLDVVRQVAKWRDKGINL-RVAVNVSARQLADQTIFTALKQALQELNFEYCPIDVELTESCLIENEELAL 544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 573 AILTRLTEMGVKASIDDFGTGYSSLLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQ 652
Cdd:PRK10060 545 SVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVETAKE 624
|
410 420
....*....|....*....|....*...
gi 447068068 653 QQFLTQLGCHTLQGFLLGKPRTAEEIAR 680
Cdd:PRK10060 625 DAFLTKNGVNERQGFLFAKPMPAVAFER 652
|
|
| EAL |
cd01948 |
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
437-677 |
1.06e-104 |
|
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.
Pssm-ID: 238923 [Multi-domain] Cd Length: 240 Bit Score: 318.72 E-value: 1.06e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 437 NDLWLALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWVIDEACRQLREWHLQ 516
Cdd:cd01948 1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 517 GYALWsVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKPEQSVAILTRLTEMGVKASIDDFGTGYSS 596
Cdd:cd01948 81 GPDLR-LSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 597 LLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKPRTAE 676
Cdd:cd01948 160 LSYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAE 239
|
.
gi 447068068 677 E 677
Cdd:cd01948 240 E 240
|
|
| EAL |
smart00052 |
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ... |
436-677 |
2.37e-94 |
|
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.
Pssm-ID: 214491 [Multi-domain] Cd Length: 242 Bit Score: 292.20 E-value: 2.37e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 436 MNDLWLALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWVIDEACRQLREWHL 515
Cdd:smart00052 1 ERELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 516 QGYALWSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKPEQSVAILTRLTEMGVKASIDDFGTGYS 595
Cdd:smart00052 81 QGPPPLLISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 596 SLLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKPRTA 675
Cdd:smart00052 161 SLSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPL 240
|
..
gi 447068068 676 EE 677
Cdd:smart00052 241 DD 242
|
|
| EAL |
pfam00563 |
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
436-672 |
4.41e-75 |
|
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.
Pssm-ID: 425752 [Multi-domain] Cd Length: 235 Bit Score: 241.45 E-value: 4.41e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 436 MNDLWLALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWVIDEACRQLREWHL 515
Cdd:pfam00563 1 ARALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQLQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 516 QGYAlwSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKPEQSVAILTRLTEMGVKASIDDFGTGYS 595
Cdd:pfam00563 81 GPDI--KLSINLSPASLADPGFLELLRALLKQAGPPPSRLVLEITESDLLARLEALREVLKRLRALGIRIALDDFGTGYS 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447068068 596 SLLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKP 672
Cdd:pfam00563 159 SLSYLLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
|
|
| T2SS_HK |
NF038348 |
histidine kinase; |
6-281 |
3.24e-67 |
|
histidine kinase;
Pssm-ID: 439642 [Multi-domain] Cd Length: 574 Bit Score: 231.38 E-value: 3.24e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 6 YNHILVAVSFAVAIFASYTALNMAGRVAGSARSNARI-WLIGGGFALGVGIWAMHFVGMLAMDHAMNMRFDPFLTGLSML 84
Cdd:NF038348 5 YDLSLVLLSLVIATLASYTALDLSALISLLDKPRLRRaWLAGGAAAMGTGIWAMHFVGMLAFSLPIPLGYDLRETGLSLA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 85 IAIGSSLFALWLVSAEKLRLRRLLPGALVMGLGISAMHYTGMAALQFASIIVWNSAWVALSIIIALLASCGALWLTFRLR 164
Cdd:NF038348 85 IAMVVSYFALNAVTRAKLTRERLAAGGVLMGLGIAGMHYTGMAALQMQPGIRYDSALFVASIGIAILASTAALWLAHRLR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 165 HEGTD-VALRRAGAAVLMGIAIAGMHYAGMKAAHFPQNWP-MEHRGVDSNWLAVLVSVVALTILGITLLVSLFDAR---- 238
Cdd:NF038348 165 TENAGrVIVKRIGAATVMGVAITGMHYTGMAAAHFAPNARcGAANGISGPWLGTTIALFTATILIVTLVISRFDARtmfl 244
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 447068068 239 ----------LQARTALLASSLAQanQELAQLALHDTltrlpnRVLLEDRLEQ 281
Cdd:NF038348 245 rgitdaledlVQLRTAELEGALRQ--YELTTETLQRT------RVHMEREIEE 289
|
|
| GGDEF |
TIGR00254 |
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by ... |
260-418 |
1.15e-39 |
|
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by many proteins carrying the domain. There is evidence that the domain has diguanylate cyclase activity. Several proteins carrying this domain also carry domains with functions relating to environmental sensing. These include PleD, a response regulator protein involved in the swarmer-to-stalked cell transition in Caulobacter crescentus, and FixL, a heme-containing oxygen sensor protein. [Regulatory functions, Small molecule interactions, Signal transduction, Other]
Pssm-ID: 272984 [Multi-domain] Cd Length: 165 Bit Score: 143.63 E-value: 1.15e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 260 LALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSGQFTLARI 339
Cdd:TIGR00254 1 QAVRDPLTGLYNRRYLEEMLDSELKRARRFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 340 GGDEFVLLAEVSAPDEAASLASALVHSIDA-PFTIDPYELV-VTLSVGIALYPLDGKNERELMFNADAAMYHTKHTGRNG 417
Cdd:TIGR00254 81 GGEEFVVILPGTPLEDALSKAERLRDAINSkPIEVAGSETLtVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAGRNR 160
|
.
gi 447068068 418 Y 418
Cdd:TIGR00254 161 V 161
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG5001 |
COG5001 |
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ... |
10-686 |
0e+00 |
|
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];
Pssm-ID: 444025 [Multi-domain] Cd Length: 678 Bit Score: 621.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 10 LVAVSFAVAIFASYTALNMAGRVAGSARSNARIWLIGGGFALGVGIWAMHFVGMLAMDHAMNMRFDPFLTGLSMLIAIGS 89
Cdd:COG5001 1 LLALAALLLLLLALLLALLLLALLLLALLLAALLALALLLLLLLLLLALLLAALLLLALLALLALLLLAAALLALALAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 90 SLFALWLVSAEKLRLRRLLPGALVMGLGISAMHYTGMAALQFASIIVWNSAWVALSIIIALLAScGALWLTFRLRHEGTD 169
Cdd:COG5001 81 LLAALLAALLLLLLLLLALLVLLLLLLLLLALLALLAALLARALAALLLAAASAALLAAALGAA-LLAALALALLLALAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 170 VALRRAGAAVLMGIAIAGMHYAGMKAAHFPQNWPMEHRGVDSNWLAVLVSVVALTILGITLLVSLFDARLQARTALLASS 249
Cdd:COG5001 160 ALLALLLLLLLALLLLLLLLLLLALLLLLLLALLLRLLLLLRGGRLLRLALRLLLGLLLLGLLLLLLLVAVLAIARLITE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 250 LAQANQELAQLALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQP 329
Cdd:COG5001 240 RKRAEERLRHLAYHDPLTGLPNRRLFLDRLEQALARARRSGRRLALLFIDLDRFKEINDTLGHAAGDELLREVARRLRAC 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 330 LSGQFTLARIGGDEF-VLLAEVSAPDEAASLASALVHSIDAPFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMY 408
Cdd:COG5001 320 LREGDTVARLGGDEFaVLLPDLDDPEDAEAVAERILAALAEPFELDGHELYVSASIGIALYPDDGADAEELLRNADLAMY 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 409 HTKHTGRNGYHFFQPSMNMLAQTQLQLMNDLWLALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPL 488
Cdd:COG5001 400 RAKAAGRNRYRFFDPEMDERARERLELEADLRRALERGELELHYQPQVDLATGRIVGAEALLRWQHPERGLVSPAEFIPL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 489 AEKTGLIVTIGSWVIDEACRQLREWHLQGYALWSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKP 568
Cdd:COG5001 480 AEETGLIVPLGEWVLREACRQLAAWQDAGLPDLRVAVNLSARQLRDPDLVDRVRRALAETGLPPSRLELEITESALLEDP 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 569 EQSVAILTRLTEMGVKASIDDFGTGYSSLLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVE 648
Cdd:COG5001 560 EEALETLRALRALGVRIALDDFGTGYSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEVVAEGVE 639
|
650 660 670
....*....|....*....|....*....|....*...
gi 447068068 649 NETQQQFLTQLGCHTLQGFLLGKPRTAEEIARDIRDPA 686
Cdd:COG5001 640 TEEQLEFLRELGCDYAQGYLFSRPLPAEELEALLRARA 677
|
|
| EAL |
COG2200 |
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) ... |
126-683 |
9.07e-116 |
|
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) [Signal transduction mechanisms];
Pssm-ID: 441802 [Multi-domain] Cd Length: 576 Bit Score: 359.87 E-value: 9.07e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 126 MAALQFASIIVWNSAWVALSIIIALLASCGALWLTFRLRHEGTDVALRRAGAAVLMGIAIAGMHYAGMKAAHFPQNWPME 205
Cdd:COG2200 20 LAEALALLLLLALLLLALASALLLAVAALLAALLAALLLLLALALLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLLL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 206 HRGVDSNWLAVLVSVVALTILGITLLVSLFDARLQARTALLASSLAQANQELAQLALHDTLTRLPNRVLLEDRLEQAISK 285
Cdd:COG2200 100 LLLLALLLAALLALLLLLLLLLLLLLLSLLLLLVLVLLRLALELLLALLLLALLALLDLLLLLLLRRLLLLLLLLLLLLL 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 286 ANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSGQFTLARIGGDEFVLLAEVSAPDEAASLASALVH 365
Cdd:COG2200 180 LALALLALLLLLLLLLLLLLDNDGLGGAGLLLLLLLALLLLLLLARLLLALLGGGGGGFLLLLLLLAAAAAAAAALRLLL 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 366 SIDAPFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMYHTKHTGRNGYHFFQPSMNMLAQTQLQLMNDLWLALER 445
Cdd:COG2200 260 LLLLEPLLLGGGLVVVASSGGGAAAPDDGADAALLLAAAAAAAAAAAGGGRGRVVFFAAAEARARRRLALESELREALEE 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 446 QELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWVIDEACRQLREWHLQGYALWsVAV 525
Cdd:COG2200 340 GELRLYYQPIVDLRTGRVVGYEALLRWRHPDGGLISPAEFIPAAERSGLIVELDRWVLERALRQLARWPERGLDLR-LSV 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 526 NLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKPEQSVAILTRLTEMGVKASIDDFGTGYSSLLYLKRLPA 605
Cdd:COG2200 419 NLSARSLLDPDFLERLLELLAEYGLPPERLVLEITESALLEDLEAAIELLARLRALGVRIALDDFGTGYSSLSYLKRLPP 498
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447068068 606 CELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKPRTAEEIARDIR 683
Cdd:COG2200 499 DYLKIDRSFVRDIARDPRDQAIVRAIVALAHRLGLKVVAEGVETEEQLEALRELGCDYAQGYLFGRPLPLEELEALLR 576
|
|
| PRK10060 |
PRK10060 |
cyclic di-GMP phosphodiesterase; |
253-680 |
5.21e-109 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 236645 [Multi-domain] Cd Length: 663 Bit Score: 344.74 E-value: 5.21e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 253 ANQELAQLALHDTLTRLPNRVLLEDRLEQAISKANRESTsfALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSG 332
Cdd:PRK10060 229 AQERLRILANTDSITGLPNRNAIQELIDHAINAADNNQV--GIVYLDLDNFKKVNDAYGHMFGDQLLQDVSLAILSCLEE 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 333 QFTLARIGGDEFVLLAEVSAPDEAASLASALVHSIDAPFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMYHTKH 412
Cdd:PRK10060 307 DQTLARLGGDEFLVLASHTSQAALEAMASRILTRLRLPFRIGLIEVYTGCSIGIALAPEHGDDSESLIRSADTAMYTAKE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 413 TGRNGYHFFQPSMNMLAQTQLQLMNDLWLALERQELRLVYQPKFQApAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKT 492
Cdd:PRK10060 387 GGRGQFCVFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITW-RGEVRSLEALVRWQSPERGLIPPLEFISYAEES 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 493 GLIVTIGSWVIDEACRQLREWHLQGYALwSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKPEQSV 572
Cdd:PRK10060 466 GLIVPLGRWVMLDVVRQVAKWRDKGINL-RVAVNVSARQLADQTIFTALKQALQELNFEYCPIDVELTESCLIENEELAL 544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 573 AILTRLTEMGVKASIDDFGTGYSSLLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQ 652
Cdd:PRK10060 545 SVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVETAKE 624
|
410 420
....*....|....*....|....*...
gi 447068068 653 QQFLTQLGCHTLQGFLLGKPRTAEEIAR 680
Cdd:PRK10060 625 DAFLTKNGVNERQGFLFAKPMPAVAFER 652
|
|
| PRK11359 |
PRK11359 |
cyclic-di-GMP phosphodiesterase; Provisional |
234-678 |
8.32e-109 |
|
cyclic-di-GMP phosphodiesterase; Provisional
Pssm-ID: 183097 [Multi-domain] Cd Length: 799 Bit Score: 347.91 E-value: 8.32e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 234 LFDARLQARTALLASSLAQANQELAQLAL--------------HDTLTRLPNRVLLEDRLEQAISKAnresTSFALLFMD 299
Cdd:PRK11359 335 QIKTSSGAETSAFIERVADISQHLAALALeqeksrqhieqliqFDPLTGLPNRNNLHNYLDDLVDKA----VSPVVYLIG 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 300 LDGFKAVNDAYGHDIGDKLLVAVTHRLNQPL-SGQFtLARIGGDEFVLLAEVSAPDEAASLASALVHSIDAPFTIDPYEL 378
Cdd:PRK11359 411 VDHFQDVIDSLGYAWADQALLEVVNRFREKLkPDQY-LCRIEGTQFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPF 489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 379 VVTLSVGIAlYPLdGKNERELMFNADAAMYHTKHTGRNGYHFFQPSMNMLAQTQLQLMNDLWLALERQELRLVYQPKFQA 458
Cdd:PRK11359 490 PLTLSIGIS-YDV-GKNRDYLLSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIFA 567
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 459 PAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWVIDEACRQLREWHLQGYALWSVAVNLSALQFEQPGLV 538
Cdd:PRK11359 568 ETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRSQNIHIPALSVNLSALHFRSNQLP 647
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 539 DTITRSLARHSIRPDLLILEITETTAMNKPEQSVAILTRLTEMGVKASIDDFGTGYSSLLYLKRLPACELKIDRAFVHEL 618
Cdd:PRK11359 648 NQVSDAMQAWGIDGHQLTVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRC 727
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 619 SEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKPRTAEEI 678
Cdd:PRK11359 728 LTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEI 787
|
|
| EAL |
cd01948 |
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
437-677 |
1.06e-104 |
|
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.
Pssm-ID: 238923 [Multi-domain] Cd Length: 240 Bit Score: 318.72 E-value: 1.06e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 437 NDLWLALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWVIDEACRQLREWHLQ 516
Cdd:cd01948 1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 517 GYALWsVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKPEQSVAILTRLTEMGVKASIDDFGTGYSS 596
Cdd:cd01948 81 GPDLR-LSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 597 LLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKPRTAE 676
Cdd:cd01948 160 LSYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAE 239
|
.
gi 447068068 677 E 677
Cdd:cd01948 240 E 240
|
|
| MHYT |
COG3300 |
MHYT domain, NO-binding membrane sensor [Signal transduction mechanisms]; |
3-444 |
1.90e-100 |
|
MHYT domain, NO-binding membrane sensor [Signal transduction mechanisms];
Pssm-ID: 442529 [Multi-domain] Cd Length: 440 Bit Score: 315.36 E-value: 1.90e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 3 VSEYNHILVAVSFAVAIFASYTALNMAGRVAGSARSNARIWLIGGGFALGVGIWAMHFVGMLAMDHAMNMRFDPFLTGLS 82
Cdd:COG3300 4 AGSHDPWLVALSVLIAVLGSYTALDLARRARAASGRARRAWLALAALALGGGIWSMHFIAMLAFRLPVPVGYDPPLTLLS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 83 MLIAIGSSLFALWLVSAEKLRLRRLLPGALVMGLGISAMHYTGMAALQFASIIVWNSAWVALSIIIALLASCGALWLTFR 162
Cdd:COG3300 84 LLVAILASGLALALASRRRLSRLRLLLGGLLMGLGIAAMHYTGMAAMRMAGAISYDPALVALSVLIAVVASTAALWLAFR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 163 LRHegtdvALRRAGAAVLMGIAIAGMHYAGMKAAHFPQNW--PMEHRGVDSNWLAVLVSVVALTILGITLLVSLFDARLq 240
Cdd:COG3300 164 LRS-----LRRRLGAALVMGLAICGMHYTGMAAATFVPDPgaPAPAPGLSPTLLALAVAVVTLLILGLALLASLLDDAR- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 241 aRTALLASSLAQANQELAQLALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLV 320
Cdd:COG3300 238 -RRARAARELASLRLLAALALAGLLLTGLLLALEARGALAALLGAALDELLLDLLLLLDLDGDAALLLALGELLADLLLA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 321 AVTHRLNQPLSGQFTLARIGGDEFVLLAEVSAPDEAASLASALVHSIDAPFTIDPYELVVTLSVGIALYPLDGKNERELM 400
Cdd:COG3300 317 LVAARVVARVRLVARVGGDERDEIVAEDRLRRAEAEAAADAARLALAAAASALSLDALLLLALLAAAALALALAALLALR 396
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 447068068 401 FNADAAMYHTKHTGRNGYHFFQPSMNMLAQTQLQLMNDLWLALE 444
Cdd:COG3300 397 ALAAADALTVEADASSAAAELLLAAALLLLLLLLLLLLLLLARD 440
|
|
| EAL |
smart00052 |
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ... |
436-677 |
2.37e-94 |
|
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.
Pssm-ID: 214491 [Multi-domain] Cd Length: 242 Bit Score: 292.20 E-value: 2.37e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 436 MNDLWLALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWVIDEACRQLREWHL 515
Cdd:smart00052 1 ERELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 516 QGYALWSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKPEQSVAILTRLTEMGVKASIDDFGTGYS 595
Cdd:smart00052 81 QGPPPLLISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 596 SLLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKPRTA 675
Cdd:smart00052 161 SLSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPL 240
|
..
gi 447068068 676 EE 677
Cdd:smart00052 241 DD 242
|
|
| PRK13561 |
PRK13561 |
putative diguanylate cyclase; Provisional |
249-680 |
5.62e-89 |
|
putative diguanylate cyclase; Provisional
Pssm-ID: 184143 [Multi-domain] Cd Length: 651 Bit Score: 291.62 E-value: 5.62e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 249 SLAQANQELAQLALHDTLTRLPNRVLLEDRLEQAISKANRestsFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQ 328
Cdd:PRK13561 219 LLQRQYEEQSRNATRFPVSDLPNKALLMALLEQVVARKQT----TALMIITCETLRDTAGVLKEAQREILLLTLVEKLKS 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 329 PLSGQFTLARIGGDEFVLLAE-VSAPDEAASLASALVHSIDAPFTIDPYELVVTLSVGIALYpLDGKNERELMFNADAAM 407
Cdd:PRK13561 295 VLSPRMVLAQISGYDFAIIANgVKEPWHAITLGQQVLTIINERLPIQRIQLRPSCSIGIAMF-YGDLTAEQLYSRAISAA 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 408 YHTKHTGRNGYHFFQPSMNMLAQTQLQLMNDLWLALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLP 487
Cdd:PRK13561 374 FTARRKGKNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMRSGKLVSAEALLRMQQPDGSWDLPEGLID 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 488 LAEKTGLIVTIGSWVIDEACRQLREWHLQGYALwSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNK 567
Cdd:PRK13561 454 RIESCGLMVTVGHWVLEESCRLLAAWQERGIML-PLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDD 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 568 PEQSVAILTRLTEMGVKASIDDFGTGYSSLLYL---KRLPACELKIDRAFVHELSEASdgaTIVAAIVALAKALNLQIVA 644
Cdd:PRK13561 533 PHAAVAILRPLRNAGVRVALDDFGMGYAGLRQLqhmKSLPIDVLKIDKMFVDGLPEDD---SMVAAIIMLAQSLNLQVIA 609
|
410 420 430
....*....|....*....|....*....|....*.
gi 447068068 645 EGVENETQQQFLTQLGCHTLQGFLLGKPRTAEEIAR 680
Cdd:PRK13561 610 EGVETEAQRDWLLKAGVGIAQGFLFARALPIEIFEE 645
|
|
| EAL |
pfam00563 |
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
436-672 |
4.41e-75 |
|
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.
Pssm-ID: 425752 [Multi-domain] Cd Length: 235 Bit Score: 241.45 E-value: 4.41e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 436 MNDLWLALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWVIDEACRQLREWHL 515
Cdd:pfam00563 1 ARALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQLQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 516 QGYAlwSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKPEQSVAILTRLTEMGVKASIDDFGTGYS 595
Cdd:pfam00563 81 GPDI--KLSINLSPASLADPGFLELLRALLKQAGPPPSRLVLEITESDLLARLEALREVLKRLRALGIRIALDDFGTGYS 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447068068 596 SLLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKP 672
Cdd:pfam00563 159 SLSYLLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
|
|
| PRK11829 |
PRK11829 |
biofilm formation regulator HmsP; Provisional |
250-672 |
2.44e-73 |
|
biofilm formation regulator HmsP; Provisional
Pssm-ID: 183329 [Multi-domain] Cd Length: 660 Bit Score: 250.24 E-value: 2.44e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 250 LAQANQELAQLALHDTLTRLPNRVLLEDRLEQAISKANREStSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQP 329
Cdd:PRK11829 221 LADAYADMGRISHRFPVTELPNRSLFISLLEKEIASSTRTD-HFHLLVIGIETLQEVSGAMSEAQHQQLLLTIVQRIEQC 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 330 LSGQFTLARIGGDEFVLLA-EVSAPDEAASLASALVHSIDAPFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMY 408
Cdd:PRK11829 300 IDDSDLLAQLSKTEFAVLArGTRRSFPAMQLARRIMSQVTQPLFFDEITLRPSASIGITRYQAQQDTAESMMRNASTAMM 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 409 HTKHTGRNGYHFFQPSMNMLAQTQLQLMNDLWLALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPL 488
Cdd:PRK11829 380 AAHHEGRNQIMVFEPHLIEKTHKRLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSYVLPSGFVHF 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 489 AEKTGLIVTIGSWVIDEACRQLREWHLQGYALwSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNKP 568
Cdd:PRK11829 460 AEEEGMMVPLGNWVLEEACRILADWKARGVSL-PLSVNISGLQVQNKQFLPHLKTLISHYHIDPQQLLLEITETAQIQDL 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 569 EQSVAILTRLTEMGVKASIDDFGTGYSSLLYL---KRLPACELKIDRAFVHELSEasDGAtIVAAIVALAKALNLQIVAE 645
Cdd:PRK11829 539 DEALRLLRELQGLGLLIALDDFGIGYSSLRYLnhlKSLPIHMIKLDKSFVKNLPE--DDA-IARIISCVSDVLKVRVMAE 615
|
410 420
....*....|....*....|....*..
gi 447068068 646 GVENETQQQFLTQLGCHTLQGFLLGKP 672
Cdd:PRK11829 616 GVETEEQRQWLLEHGIQCGQGFLFSPP 642
|
|
| T2SS_HK |
NF038348 |
histidine kinase; |
6-281 |
3.24e-67 |
|
histidine kinase;
Pssm-ID: 439642 [Multi-domain] Cd Length: 574 Bit Score: 231.38 E-value: 3.24e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 6 YNHILVAVSFAVAIFASYTALNMAGRVAGSARSNARI-WLIGGGFALGVGIWAMHFVGMLAMDHAMNMRFDPFLTGLSML 84
Cdd:NF038348 5 YDLSLVLLSLVIATLASYTALDLSALISLLDKPRLRRaWLAGGAAAMGTGIWAMHFVGMLAFSLPIPLGYDLRETGLSLA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 85 IAIGSSLFALWLVSAEKLRLRRLLPGALVMGLGISAMHYTGMAALQFASIIVWNSAWVALSIIIALLASCGALWLTFRLR 164
Cdd:NF038348 85 IAMVVSYFALNAVTRAKLTRERLAAGGVLMGLGIAGMHYTGMAALQMQPGIRYDSALFVASIGIAILASTAALWLAHRLR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 165 HEGTD-VALRRAGAAVLMGIAIAGMHYAGMKAAHFPQNWP-MEHRGVDSNWLAVLVSVVALTILGITLLVSLFDAR---- 238
Cdd:NF038348 165 TENAGrVIVKRIGAATVMGVAITGMHYTGMAAAHFAPNARcGAANGISGPWLGTTIALFTATILIVTLVISRFDARtmfl 244
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 447068068 239 ----------LQARTALLASSLAQanQELAQLALHDTltrlpnRVLLEDRLEQ 281
Cdd:NF038348 245 rgitdaledlVQLRTAELEGALRQ--YELTTETLQRT------RVHMEREIEE 289
|
|
| YjcC |
COG4943 |
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ... |
442-680 |
6.61e-67 |
|
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];
Pssm-ID: 443970 [Multi-domain] Cd Length: 528 Bit Score: 229.42 E-value: 6.61e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 442 ALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWVIDEACRQLREWhLQGYALW 521
Cdd:COG4943 279 AIKRREFYVHYQPIVDLKTGRCVGAEALVRWRDPDGSVISPDIFIPLAEQSGLISPLTRQVIEQVFRDLGDL-LAADPDF 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 522 SVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMNkPEQSVAILTRLTEMGVKASIDDFGTGYSSLLYLK 601
Cdd:COG4943 358 HISINLSASDLLSPRFLDDLERLLARTGVAPQQIVLEITERGFID-PAKARAVIAALREAGHRIAIDDFGTGYSSLSYLQ 436
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447068068 602 RLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKPRTAEEIAR 680
Cdd:COG4943 437 TLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMAKTLNLDVVAEGVETEEQADYLRARGVQYGQGWLFAKPLPAEEFIA 515
|
|
| GGDEF |
cd01949 |
Diguanylate-cyclase (DGC) or GGDEF domain; Diguanylate-cyclase (DGC) or GGDEF domain: ... |
262-419 |
2.51e-58 |
|
Diguanylate-cyclase (DGC) or GGDEF domain; Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.
Pssm-ID: 143635 [Multi-domain] Cd Length: 158 Bit Score: 194.31 E-value: 2.51e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 262 LHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSGQFTLARIGG 341
Cdd:cd01949 1 YTDPLTGLPNRRAFEERLERLLARARRSGRPLALLLIDIDHFKQINDTYGHAAGDEVLKEVAERLRSSLRESDLVARLGG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447068068 342 DEFVLLAEVSAPDEAASLASALVHSIDAPFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMYHTKHTGRNGYH 419
Cdd:cd01949 81 DEFAILLPGTDLEEAEALAERLREAIEEPFFIDGQEIRVTASIGIATYPEDGEDAEELLRRADEALYRAKRSGRNRVV 158
|
|
| GGDEF |
COG2199 |
GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants ... |
195-421 |
2.66e-57 |
|
GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants [Signal transduction mechanisms];
Pssm-ID: 441801 [Multi-domain] Cd Length: 275 Bit Score: 195.58 E-value: 2.66e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 195 AAHFPQNWPMEHRGVDSNWLAVLVSVVALTILGITLLVSLFDARLQARTALLASSLAQANQELAQLALHDTLTRLPNRVL 274
Cdd:COG2199 48 LLLLLLLLLLLLLVLLLLALGLLLLALLLLSLVLELLLLLLALLLLLLALEDITELRRLEERLRRLATHDPLTGLPNRRA 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 275 LEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSGQFTLARIGGDEFVLLAEVSAPD 354
Cdd:COG2199 128 FEERLERELARARREGRPLALLLIDLDHFKRINDTYGHAAGDEVLKEVARRLRASLRESDLVARLGGDEFAVLLPGTDLE 207
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447068068 355 EAASLASALVHSIDA-PFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMYHTKHTGRNGYHFF 421
Cdd:COG2199 208 EAEALAERLREALEQlPFELEGKELRVTVSIGVALYPEDGDSAEELLRRADLALYRAKRAGRNRVVVY 275
|
|
| PRK09776 |
PRK09776 |
putative diguanylate cyclase; Provisional |
256-672 |
8.01e-55 |
|
putative diguanylate cyclase; Provisional
Pssm-ID: 182070 [Multi-domain] Cd Length: 1092 Bit Score: 203.37 E-value: 8.01e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 256 ELAQLALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSGQFT 335
Cdd:PRK09776 660 QLSYSASHDALTHLANRASFEKQLRRLLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSMLRSSDV 739
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 336 LARIGGDEFVLLAEVSAPDEAASLASALVHSI-DAPFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMYHTKHTG 414
Cdd:PRK09776 740 LARLGGDEFGLLLPDCNVESARFIATRIISAInDYHFPWEGRVYRVGASAGITLIDANNHQASEVMSQADIACYAAKNAG 819
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 415 RNGYHFFQP--SMNMLAQTQLQLMNDLWLALERQELRLVYQPKfqAPAGPI-VGF-EALLRWYHPKQGVLNPDQFLPLAE 490
Cdd:PRK09776 820 RGRVTVYEPqqAAAHSEHRALSLAEQWRMIKENQLMMLAHGVA--SPRIPEaRNHwLISLRLWDPEGEIIDEGAFRPAAE 897
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 491 KTGLIVTIGSWVIDEACRQlrewhlQGYAL----WSVAVNLSALQFEQPGLVDTITRSLARHSIRPDLLILEITETTAMN 566
Cdd:PRK09776 898 DPALMHALDRRVIHEFFRQ------AAKAVaskgLSIALPLSVAGLSSPTLLPFLLEQLENSPLPPRLLHLEITETALLN 971
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 567 KPEQSVAILTRLTEMGVKASIDDFGTGYSSLLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEG 646
Cdd:PRK09776 972 HAESASRLVQKLRLAGCRVVLSDFGRGLSSFNYLKAFMADYLKLDGELVANLHGNLMDEMLISIIQGHAQRLGMKTIAGP 1051
|
410 420
....*....|....*....|....*.
gi 447068068 647 VENETQQQFLTQLGCHTLQGFLLGKP 672
Cdd:PRK09776 1052 VELPLVLDTLSGIGVDLAYGYAIARP 1077
|
|
| GGDEF |
smart00267 |
diguanylate cyclase; Diguanylate cyclase, present in a variety of bacteria. |
259-421 |
7.67e-53 |
|
diguanylate cyclase; Diguanylate cyclase, present in a variety of bacteria.
Pssm-ID: 128563 [Multi-domain] Cd Length: 163 Bit Score: 179.75 E-value: 7.67e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 259 QLALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSGQFTLAR 338
Cdd:smart00267 1 RLAFRDPLTGLPNRRYFEEELEQELQRAQRQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPGDLLAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 339 IGGDEFVLLAEVSAPDEAASLASALVHSIDAPFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMYHTKHTGRNGY 418
Cdd:smart00267 81 LGGDEFALLLPETSLEEAIALAERILQQLREPIIIHGIPLYLTISIGVAAYPNPGEDAEDLLKRADTALYQAKKAGRNQV 160
|
...
gi 447068068 419 HFF 421
Cdd:smart00267 161 AVY 163
|
|
| GGDEF |
pfam00990 |
Diguanylate cyclase, GGDEF domain; This domain is found linked to a wide range of ... |
261-416 |
4.46e-50 |
|
Diguanylate cyclase, GGDEF domain; This domain is found linked to a wide range of non-homologous domains in a variety of bacteria. It has been shown to be homologous to the adenylyl cyclase catalytic domain and has diguanylate cyclase activity. This observation correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. In the WspR protein of Pseudomonas aeruginosa, the GGDEF domain acts as a diguanylate cyclase, PDB:3bre, when the whole molecule appears to form a tetramer consisting of two symmetrically-related dimers representing a biological unit. The active site is the GGD/EF motif, buried in the structure, and the cyclic dimeric guanosine monophosphate (c-di-GMP) bind to the inhibitory-motif RxxD on the surface. The enzyme thus catalyzes the cyclization of two guanosine triphosphate (GTP) molecules to one c-di-GMP molecule.
Pssm-ID: 425976 [Multi-domain] Cd Length: 160 Bit Score: 172.05 E-value: 4.46e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 261 ALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSGQFTLARIG 340
Cdd:pfam00990 1 AAHDPLTGLPNRRYFEEQLEQELQRALREGSPVAVLLIDLDNFKRINDTYGHSVGDEVLQEVAQRLSSSLRRSDLVARLG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447068068 341 GDEF-VLLAEVSAP--DEAASLASALVHSIDAPFTIDPYELVVTLSVGIALYPLDGKNERELMFNADAAMYHTKHTGRN 416
Cdd:pfam00990 81 GDEFaILLPETSLEgaQELAERIRRLLAKLKIPHTVSGLPLYVTISIGIAAYPNDGEDPEDLLKRADTALYQAKQAGRN 159
|
|
| PRK10551 |
PRK10551 |
cyclic di-GMP phosphodiesterase; |
441-680 |
6.03e-40 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 182541 [Multi-domain] Cd Length: 518 Bit Score: 153.99 E-value: 6.03e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 441 LALERQELRLVYQPKFQAPAGPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWV---IDEACRQLREWHLQG 517
Cdd:PRK10551 270 TGIKRGQFYVEYQPVVDTQTLRVTGLEALLRWRHPTAGEIPPDAFINYAEAQKLIVPLTQHLfelIARDAAELQKVLPVG 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 518 YALwsvAVNLSALQFEQPGLVDTITRSLArhSIRPD--LLILEITETTAMNKpEQSVAILTRLTEMGVKASIDDFGTGYS 595
Cdd:PRK10551 350 AKL---GINISPAHLHSDSFKADVQRLLA--SLPADhfQIVLEITERDMVQE-EEATKLFAWLHSQGIEIAIDDFGTGHS 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 596 SLLYLKRLPACELKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKPRTA 675
Cdd:PRK10551 424 ALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLRERGVNFLQGYWISRPLPL 503
|
....*
gi 447068068 676 EEIAR 680
Cdd:PRK10551 504 EDFVR 508
|
|
| GGDEF |
TIGR00254 |
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by ... |
260-418 |
1.15e-39 |
|
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by many proteins carrying the domain. There is evidence that the domain has diguanylate cyclase activity. Several proteins carrying this domain also carry domains with functions relating to environmental sensing. These include PleD, a response regulator protein involved in the swarmer-to-stalked cell transition in Caulobacter crescentus, and FixL, a heme-containing oxygen sensor protein. [Regulatory functions, Small molecule interactions, Signal transduction, Other]
Pssm-ID: 272984 [Multi-domain] Cd Length: 165 Bit Score: 143.63 E-value: 1.15e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 260 LALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSGQFTLARI 339
Cdd:TIGR00254 1 QAVRDPLTGLYNRRYLEEMLDSELKRARRFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 340 GGDEFVLLAEVSAPDEAASLASALVHSIDA-PFTIDPYELV-VTLSVGIALYPLDGKNERELMFNADAAMYHTKHTGRNG 417
Cdd:TIGR00254 81 GGEEFVVILPGTPLEDALSKAERLRDAINSkPIEVAGSETLtVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAGRNR 160
|
.
gi 447068068 418 Y 418
Cdd:TIGR00254 161 V 161
|
|
| pleD |
PRK09581 |
response regulator PleD; Reviewed |
237-416 |
1.37e-26 |
|
response regulator PleD; Reviewed
Pssm-ID: 236577 [Multi-domain] Cd Length: 457 Bit Score: 113.46 E-value: 1.37e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 237 ARLQAR----TALLASSLAQAnqelAQLALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGH 312
Cdd:PRK09581 268 VRTQIRrkryQDALRNNLEQS----IEMAVTDGLTGLHNRRYFDMHLKNLIERANERGKPLSLMMIDIDHFKKVNDTYGH 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 313 DIGDKLLVAVTHRLNQPLSGQFTLARIGGDEFVLLAEVSAPDEAASLASALVHSI-DAPFTI--DPYELVVTLSVGIALY 389
Cdd:PRK09581 344 DAGDEVLREFAKRLRNNIRGTDLIARYGGEEFVVVMPDTDIEDAIAVAERIRRKIaEEPFIIsdGKERLNVTVSIGVAEL 423
|
170 180
....*....|....*....|....*..
gi 447068068 390 PLDGKNERELMFNADAAMYHTKHTGRN 416
Cdd:PRK09581 424 RPSGDTIEALIKRADKALYEAKNTGRN 450
|
|
| PRK09894 |
PRK09894 |
diguanylate cyclase; Provisional |
264-416 |
5.26e-23 |
|
diguanylate cyclase; Provisional
Pssm-ID: 182133 [Multi-domain] Cd Length: 296 Bit Score: 99.76 E-value: 5.26e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 264 DTLTRLPNRVLLEDRLEQaiSKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSGQFTLARIGGDE 343
Cdd:PRK09894 132 DVLTGLPGRRVLDESFDH--QLRNREPQNLYLALLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEE 209
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447068068 344 FVLLAEVSAPDEAASLASALVHSIDA-PFTIDPYELVVTLSVGIA-LYPldGKNERELMFNADAAMYHTKHTGRN 416
Cdd:PRK09894 210 FIICLKAATDEEACRAGERIRQLIANhAITHSDGRINITATFGVSrAFP--EETLDVVIGRADRAMYEGKQTGRN 282
|
|
| PRK09966 |
PRK09966 |
diguanylate cyclase DgcN; |
238-412 |
1.08e-21 |
|
diguanylate cyclase DgcN;
Pssm-ID: 182171 [Multi-domain] Cd Length: 407 Bit Score: 98.15 E-value: 1.08e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 238 RLQARtallasslaqaNQELAQLALHDTLTRLPNRVLLEDRLEQAISKANRESTSfALLFMDLDGFKAVNDAYGHDIGDK 317
Cdd:PRK09966 236 RLQAK-----------NAQLLRTALHDPLTGLANRAAFRSGINTLMNNSDARKTS-ALLFLDGDNFKYINDTWGHATGDR 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 318 LLVAVTHRLNQPLSGQFTLARIGGDEFVL-LAEVSAPDEAASLASALVHSIDAPFTI-DPYELVVTLSVGIALyPLDGKN 395
Cdd:PRK09966 304 VLIEIAKRLAEFGGLRHKAYRLGGDEFAMvLYDVQSESEVQQICSALTQIFNLPFDLhNGHQTTMTLSIGYAM-TIEHAS 382
|
170
....*....|....*..
gi 447068068 396 ERELMFNADAAMYHTKH 412
Cdd:PRK09966 383 AEKLQELADHNMYQAKH 399
|
|
| PRK15426 |
PRK15426 |
cellulose biosynthesis regulator YedQ; |
194-416 |
2.72e-20 |
|
cellulose biosynthesis regulator YedQ;
Pssm-ID: 237964 [Multi-domain] Cd Length: 570 Bit Score: 95.08 E-value: 2.72e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 194 KAAHFPQNWPMEH---RGVDSNWLAVLVSVVAL-TILGITLLVSLFDARLQARTALLASSlaqanqELAQLALHDTLTRL 269
Cdd:PRK15426 333 RLDHFDGVLVRVHtlrEGVRGDFGSISIALTLLwALFTAMLLISWYVIRRMVSNMFVLQS------SLQWQAWHDPLTRL 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 270 PNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLSGQFTLARIGGDEF-VLLA 348
Cdd:PRK15426 407 YNRGALFEKARALAKRCQRDQQPFSVIQLDLDHFKSINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFcVVLP 486
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447068068 349 EVSApDEAASLASALVHSIDAPFT-IDPYE-LVVTLSVGIALYPLDGKNERE-LMFNADAAMYHTKHTGRN 416
Cdd:PRK15426 487 GASL-AEAAQVAERIRLRINEKEIlVAKSTtIRISASLGVSSAEEDGDYDFEqLQSLADRRLYLAKQAGRN 556
|
|
| adrA |
PRK10245 |
diguanylate cyclase AdrA; Provisional |
226-416 |
1.46e-17 |
|
diguanylate cyclase AdrA; Provisional
Pssm-ID: 182329 [Multi-domain] Cd Length: 366 Bit Score: 84.88 E-value: 1.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 226 LGITLLVSLFDARLQARTALlasSLAQANQELAQLALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKA 305
Cdd:PRK10245 173 LPVIVIYPLLFAWVSYQTAT---KLAEHKRRLQVMSTRDGMTGVYNRRHWETLLRNEFDNCRRHHRDATLLIIDIDHFKS 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 306 VNDAYGHDIGDKLLVAVTHRLNQPLSGQFTLARIGGDEFVLLAeVSAPDEAASLASALVHSIDAPFTID-PYELVVTLSV 384
Cdd:PRK10245 250 INDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIM-SGTPAESAITAMSRVHEGLNTLRLPnAPQVTLRISV 328
|
170 180 190
....*....|....*....|....*....|..
gi 447068068 385 GIALYPLDGKNERELMFNADAAMYHTKHTGRN 416
Cdd:PRK10245 329 GVAPLNPQMSHYREWLKSADLALYKAKNAGRN 360
|
|
| PRK11059 |
PRK11059 |
regulatory protein CsrD; Provisional |
240-672 |
1.16e-16 |
|
regulatory protein CsrD; Provisional
Pssm-ID: 236833 [Multi-domain] Cd Length: 640 Bit Score: 83.76 E-value: 1.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 240 QARTALLASsLAQANQELAQL-------ALHDTLTRLPNRVLLEDRLEQAISKANRESTSFALLFMDLDGFKAVNDAYGH 312
Cdd:PRK11059 201 RALDHLLSE-LQDAREERSRFdtfirsnAFQDAKTGLGNRLFFDNQLATLLEDQEMVGAHGVVMLIRLPDFDLLQEEWGE 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 313 DIGDKLLVAVTHRLNQPLSGQ--FTLARIGGDEF-VLLAEVSApDEAASLASALVHSIDA---PFTIDPYELvvtLSVGI 386
Cdd:PRK11059 280 SQVEELLFELINLLSTFVMRYpgALLARYSRSDFaVLLPHRSL-KEADSLASQLLKAVDAlppPKMLDRDDF---LHIGI 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 387 ALYPlDGKNERELMFNADAAMYHTKHTGRNGYHFFQPsmnmLAQTQLQLMNDLWL-----ALERQELRLvyqpkFQAPA- 460
Cdd:PRK11059 356 CAYR-SGQSTEQVMEEAEMALRSAQLQGGNGWFVYDK----AQLPEKGRGSVRWRtlleqTLVRGGPRL-----YQQPAv 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 461 ---GPIVGFEALLRWYHPKQGVLNPDQFLPLAEKTGLIVTIGSWVIDEACRQLREWHLQGYalwsvAVNLSALQFEQPG- 536
Cdd:PRK11059 426 trdGKVHHRELFCRIRDGQGELLSAELFMPMVQQLGLSEQYDRQVIERVLPLLRYWPEENL-----SINLSVDSLLSRAf 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 537 ---LVDTI---TRSLARHsirpdlLILEITETTAMNKPEQSVAILTRLTEMGVKASIDDFGTGYSSLLYLKRLPACELKI 610
Cdd:PRK11059 501 qrwLRDTLlqcPRSQRKR------LIFELAEADVCQHISRLRPVLRMLRGLGCRLAVDQAGLTVVSTSYIKELNVELIKL 574
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 447068068 611 DRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKP 672
Cdd:PRK11059 575 HPSLVRNIHKRTENQLFVRSLVGACAGTETQVFATGVESREEWQTLQELGVSGGQGDFFAES 636
|
|
| MHYT |
pfam03707 |
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat ... |
53-106 |
1.41e-14 |
|
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat in bacterial signalling proteins. Family includes CoxC and CoxH from P.carboxydovorans. Each repeat contains two transmembrane helices. Domain is also described as the MHYT domain.
Pssm-ID: 427453 [Multi-domain] Cd Length: 54 Bit Score: 68.39 E-value: 1.41e-14
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 447068068 53 VGIWAMHFVGMLAMDHAMNMRFDPFLTGLSMLIAIGSSLFALWLVSAEKLRLRR 106
Cdd:pfam03707 1 LGIWSMHFIGMLAFRLPGPIGYDPALTALSLVIAVVASGAALWLAFRRRDTRLR 54
|
|
| MHYT |
pfam03707 |
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat ... |
116-165 |
1.90e-12 |
|
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat in bacterial signalling proteins. Family includes CoxC and CoxH from P.carboxydovorans. Each repeat contains two transmembrane helices. Domain is also described as the MHYT domain.
Pssm-ID: 427453 [Multi-domain] Cd Length: 54 Bit Score: 62.23 E-value: 1.90e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 447068068 116 LGISAMHYTGMAALQFASIIVWNSAWVALSIIIALLASCGALWLTFRLRH 165
Cdd:pfam03707 1 LGIWSMHFIGMLAFRLPGPIGYDPALTALSLVIAVVASGAALWLAFRRRD 50
|
|
| Nucleotidyl_cyc_III |
cd07556 |
Class III nucleotidyl cyclases; Class III nucleotidyl cyclases are the largest, most diverse ... |
295-387 |
1.09e-08 |
|
Class III nucleotidyl cyclases; Class III nucleotidyl cyclases are the largest, most diverse group of nucleotidyl cyclases (NC's) containing prokaryotic and eukaryotic proteins. They can be divided into two major groups; the mononucleotidyl cyclases (MNC's) and the diguanylate cyclases (DGC's). The MNC's, which include the adenylate cyclases (AC's) and the guanylate cyclases (GC's), have a conserved cyclase homology domain (CHD), while the DGC's have a conserved GGDEF domain, named after a conserved motif within this subgroup. Their products, cyclic guanylyl and adenylyl nucleotides, are second messengers that play important roles in eukaryotic signal transduction and prokaryotic sensory pathways.
Pssm-ID: 143637 [Multi-domain] Cd Length: 133 Bit Score: 54.28 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 295 LLFMDLDGFKAVNDAYGHDIGDKLLVAVTHRLNQPLS-GQFTLARIGGDEFVLLAEVSAPDEAASLASALVHSIDApftI 373
Cdd:cd07556 4 ILFADIVGFTSLADALGPDEGDELLNELAGRFDSLIRrSGDLKIKTIGDEFMVVSGLDHPAAAVAFAEDMREAVSA---L 80
|
90
....*....|....*
gi 447068068 374 DPYELV-VTLSVGIA 387
Cdd:cd07556 81 NQSEGNpVRVRIGIH 95
|
|
| YuxH |
COG3434 |
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction ... |
552-674 |
1.92e-05 |
|
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction mechanisms];
Pssm-ID: 442660 [Multi-domain] Cd Length: 407 Bit Score: 47.49 E-value: 1.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 552 PDLLILEITETTAMNkpEQSVAILTRLTEMGVKASIDDF--GTGYSSLLylkrlPACE-LKIDrafvhelSEASDGATIv 628
Cdd:COG3434 83 PERVVLEILEDVEPD--EELLEALKELKEKGYRIALDDFvlDPEWDPLL-----PLADiIKID-------VLALDLEEL- 147
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 447068068 629 AAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFLLGKPRT 674
Cdd:COG3434 148 AELVARLKRYGIKLLAEKVETREEFELCKELGFDLFQGYFFSKPEI 193
|
|
| PleD |
COG3706 |
Two-component response regulator, PleD family, consists of two REC domains and a diguanylate ... |
335-408 |
1.84e-04 |
|
Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain [Signal transduction mechanisms, Transcription];
Pssm-ID: 442920 [Multi-domain] Cd Length: 179 Bit Score: 42.97 E-value: 1.84e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447068068 335 TLARIGGDEFVLLAEVSAPDEAASLASALVHSIDAPFTIDpyelvVTLSVGIAlypldgknERELMFNADaAMY 408
Cdd:COG3706 117 LVARYGGEEFAILLPGTDLEGALAVAERIREAVAELPSLR-----VTVSIGVA--------GDSLLKRAD-ALY 176
|
|
| MHYT |
pfam03707 |
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat ... |
183-240 |
3.97e-03 |
|
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat in bacterial signalling proteins. Family includes CoxC and CoxH from P.carboxydovorans. Each repeat contains two transmembrane helices. Domain is also described as the MHYT domain.
Pssm-ID: 427453 [Multi-domain] Cd Length: 54 Bit Score: 36.03 E-value: 3.97e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447068068 183 IAIAGMHYAGMKAAHFPQnwpmehrGVDSNWLAVLVSV---VALTILGITLLVSLFDARLQ 240
Cdd:pfam03707 1 LGIWSMHFIGMLAFRLPG-------PIGYDPALTALSLviaVVASGAALWLAFRRRDTRLR 54
|
|
| PRK11596 |
PRK11596 |
cyclic-di-GMP phosphodiesterase; Provisional |
440-672 |
8.65e-03 |
|
cyclic-di-GMP phosphodiesterase; Provisional
Pssm-ID: 183222 [Multi-domain] Cd Length: 255 Bit Score: 38.44 E-value: 8.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 440 WLALERqelRLVYQPKFQApAGPIVGFEALLRWYHPkqgvLNPDQFL-PLAEKTGLIVTIGSWVIDEACRQLREWH--LQ 516
Cdd:PRK11596 25 WLQCER---AYTFQPIYRT-SGRLMAIELLTAVTHP----SNPSQRLsPERYFAEITVSHRLDVVKEQLDLLAQWAdfFV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 517 GYALWsVAVN-----LSALQfEQPGLVDTITRSlarhsirPdLLILEITETTAMNKPEqsvaILTRLTEMGvKASIDDFG 591
Cdd:PRK11596 97 RHGLL-ASVNidgptLIALR-QQPAILRLIERL-------P-WLRFELVEHIRLPKDS----PFASMCEFG-PLWLDDFG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447068068 592 TG---YSSLLYLKRlpACeLKIDRAFVHELSEASDGATIVAAIVALAKALNLQIVAEGVENETQQQFLTQLGCHTLQGFL 668
Cdd:PRK11596 162 TGmanFSALSEVRY--DY-IKVARELFIMLRQSEEGRNLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQRSPAFAAQGYF 238
|
....
gi 447068068 669 LGKP 672
Cdd:PRK11596 239 LSRP 242
|
|
| |
