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Conserved domains on  [gi|447000937|ref|WP_001078193|]
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MULTISPECIES: ribonuclease E inhibitor RraB [Acinetobacter]

Protein Classification

ribonuclease E inhibitor RraB( domain architecture ID 10536389)

ribonuclease E inhibitor RraB globally modulates RNA abundance by binding to RNase E and regulating its endonucleolytic activity in a substrate-dependent manner

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RraB pfam06877
Regulator of ribonuclease activity B; This family of proteins regulate mRNA abundance by ...
 10-108 9.76e-23

Regulator of ribonuclease activity B; This family of proteins regulate mRNA abundance by binding to RNaseE and inhibiting its endonucleolytic activity. A subset of these proteins are predicted to function as immunity proteins.


:

Pssm-ID: 429168  Cd Length: 98  Bit Score: 85.01  E-value: 9.76e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447000937   10 DDDNGNVLWQMVEDGDDLTELHEIEFSIAFQDQQNAEQCAMHLLYQEQKISLFQDDSvEPNEWIITIFVTMEPEYSDIVD 89
Cdd:pfam06877   1 RDENREVLEALKEDGDDLDKPREIEHHFYFPDEEDLEKAAEELFKLGFEVEDAEEDE-EDGPWCLDLSREMALDYEAIDA 79

                          90
                  ....*....|....*....
gi 447000937   90 LEQWFSTIAEQFNGEYDGW 108
Cdd:pfam06877  80 ITEELEELAKKFGGEYDGW 98
 
Name Accession Description Interval E-value
RraB pfam06877
Regulator of ribonuclease activity B; This family of proteins regulate mRNA abundance by ...
 10-108 9.76e-23

Regulator of ribonuclease activity B; This family of proteins regulate mRNA abundance by binding to RNaseE and inhibiting its endonucleolytic activity. A subset of these proteins are predicted to function as immunity proteins.


Pssm-ID: 429168  Cd Length: 98  Bit Score: 85.01  E-value: 9.76e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447000937   10 DDDNGNVLWQMVEDGDDLTELHEIEFSIAFQDQQNAEQCAMHLLYQEQKISLFQDDSvEPNEWIITIFVTMEPEYSDIVD 89
Cdd:pfam06877   1 RDENREVLEALKEDGDDLDKPREIEHHFYFPDEEDLEKAAEELFKLGFEVEDAEEDE-EDGPWCLDLSREMALDYEAIDA 79

                          90
                  ....*....|....*....
gi 447000937   90 LEQWFSTIAEQFNGEYDGW 108
Cdd:pfam06877  80 ITEELEELAKKFGGEYDGW 98
RraB COG3076
Regulator of RNase E activity RraB [Translation, ribosomal structure and biogenesis];
21-110 5.34e-08

Regulator of RNase E activity RraB [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442310  Cd Length: 114  Bit Score: 47.59  E-value: 5.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447000937  21 VEDGDDLTELHEIEFSIAFQDQQNAEQCAMHLLYQEQKISLFQDDSVEPNE--WIITIFVTMEPEYSDIVDLEQWFSTIA 98
Cdd:COG3076   19 LEDGSDPDALYTIEHHFSFEDFDKLEKAAVDAFKLGFEVTDAEELELEDGEtlFCFDIISESELDAELIDAQVEQLLPLA 98

                         90
                 ....*....|..
gi 447000937  99 EQFNGEYDGWGC 110
Cdd:COG3076   99 EKFGVEYDGWGT 110
hyp_HI0040 TIGR01619
TIGR01619 family protein; This model represents a hypothetical equivalog of gamma ...
 16-110 1.19e-04

TIGR01619 family protein; This model represents a hypothetical equivalog of gamma proteobacteria, includes HI0040. These sequences do not have any similarity to known proteins by PSI-BLAST.


Pssm-ID: 130680 [Multi-domain]  Cd Length: 249  Bit Score: 39.96  E-value: 1.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447000937   16 VLWQMVEDGDDLTELHEIEFSIAFQDQQN----------AEQCAMHLLYQEQKISLFQDDsvEPnEWIITIFVTMEPEYS 85
Cdd:TIGR01619 145 LLDLLKKKGRDLAALYLIEHSFHFDEEAKmfafmdelhlGDISFTSLQYSALAIMFEEDD--EP-VFLVKLEQEISLDNS 221

                          90       100
                  ....*....|....*....|....*
gi 447000937   86 DIVDLEQWFSTIAEQFNGEYDGWGC 110
Cdd:TIGR01619 222 EIFEQVEQFEDIAEQFSGEYAGWEC 246
 
Name Accession Description Interval E-value
RraB pfam06877
Regulator of ribonuclease activity B; This family of proteins regulate mRNA abundance by ...
 10-108 9.76e-23

Regulator of ribonuclease activity B; This family of proteins regulate mRNA abundance by binding to RNaseE and inhibiting its endonucleolytic activity. A subset of these proteins are predicted to function as immunity proteins.


Pssm-ID: 429168  Cd Length: 98  Bit Score: 85.01  E-value: 9.76e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447000937   10 DDDNGNVLWQMVEDGDDLTELHEIEFSIAFQDQQNAEQCAMHLLYQEQKISLFQDDSvEPNEWIITIFVTMEPEYSDIVD 89
Cdd:pfam06877   1 RDENREVLEALKEDGDDLDKPREIEHHFYFPDEEDLEKAAEELFKLGFEVEDAEEDE-EDGPWCLDLSREMALDYEAIDA 79

                          90
                  ....*....|....*....
gi 447000937   90 LEQWFSTIAEQFNGEYDGW 108
Cdd:pfam06877  80 ITEELEELAKKFGGEYDGW 98
RraB COG3076
Regulator of RNase E activity RraB [Translation, ribosomal structure and biogenesis];
21-110 5.34e-08

Regulator of RNase E activity RraB [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442310  Cd Length: 114  Bit Score: 47.59  E-value: 5.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447000937  21 VEDGDDLTELHEIEFSIAFQDQQNAEQCAMHLLYQEQKISLFQDDSVEPNE--WIITIFVTMEPEYSDIVDLEQWFSTIA 98
Cdd:COG3076   19 LEDGSDPDALYTIEHHFSFEDFDKLEKAAVDAFKLGFEVTDAEELELEDGEtlFCFDIISESELDAELIDAQVEQLLPLA 98

                         90
                 ....*....|..
gi 447000937  99 EQFNGEYDGWGC 110
Cdd:COG3076   99 EKFGVEYDGWGT 110
hyp_HI0040 TIGR01619
TIGR01619 family protein; This model represents a hypothetical equivalog of gamma ...
 16-110 1.19e-04

TIGR01619 family protein; This model represents a hypothetical equivalog of gamma proteobacteria, includes HI0040. These sequences do not have any similarity to known proteins by PSI-BLAST.


Pssm-ID: 130680 [Multi-domain]  Cd Length: 249  Bit Score: 39.96  E-value: 1.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447000937   16 VLWQMVEDGDDLTELHEIEFSIAFQDQQN----------AEQCAMHLLYQEQKISLFQDDsvEPnEWIITIFVTMEPEYS 85
Cdd:TIGR01619 145 LLDLLKKKGRDLAALYLIEHSFHFDEEAKmfafmdelhlGDISFTSLQYSALAIMFEEDD--EP-VFLVKLEQEISLDNS 221

                          90       100
                  ....*....|....*....|....*
gi 447000937   86 DIVDLEQWFSTIAEQFNGEYDGWGC 110
Cdd:TIGR01619 222 EIFEQVEQFEDIAEQFSGEYAGWEC 246
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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