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Conserved domains on  [gi|446963851|ref|WP_001041107|]
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MULTISPECIES: RNA polymerase sigma factor SigB [Staphylococcus]

Protein Classification

RNA polymerase sigma factor SigB( domain architecture ID 11483366)

RNA polymerase sigma factor SigB may play a role in the ability of the bacterium to adapt to various stresses but is not essential for its survival under these conditions

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK08583 PRK08583
RNA polymerase sigma factor SigB; Validated
2-256 1.41e-167

RNA polymerase sigma factor SigB; Validated


:

Pssm-ID: 236306 [Multi-domain]  Cd Length: 257  Bit Score: 463.01  E-value: 1.41e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   2 AKESKSANEVSPEQINQWIKEHQENKNTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFER 81
Cdd:PRK08583   1 MKESSQPTKLTKEEVNKWIAEYQENQDEEAQEKLVKHYKNLVESLAYKYSKGQSHHEDLVQVGMVGLLGAIRRYDPSFGR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  82 KFEAFLVPTVIGEIKRYLRDKTWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYN 161
Cdd:PRK08583  81 SFEAFAVPTIIGEIKRYLRDKTWSVHVPRRIKELGPKIKKAVDELTTELQRSPKISEIADRLGVSEEEVLEAMEMGKSYQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 162 ALSVDHSIEADKDGSTVTLLDIMGQQDDHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSR 241
Cdd:PRK08583 161 ALSVDHSIEADSDGSTVTLLDIVGQQEDGYELTEQRMILEKILPVLSDREKSIIQCTFIENLSQKETGERLGISQMHVSR 240
                        250
                 ....*....|....*
gi 446963851 242 LQRTAIKKLQEAAHK 256
Cdd:PRK08583 241 LQRQAIKKLREAAFL 255
 
Name Accession Description Interval E-value
PRK08583 PRK08583
RNA polymerase sigma factor SigB; Validated
2-256 1.41e-167

RNA polymerase sigma factor SigB; Validated


Pssm-ID: 236306 [Multi-domain]  Cd Length: 257  Bit Score: 463.01  E-value: 1.41e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   2 AKESKSANEVSPEQINQWIKEHQENKNTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFER 81
Cdd:PRK08583   1 MKESSQPTKLTKEEVNKWIAEYQENQDEEAQEKLVKHYKNLVESLAYKYSKGQSHHEDLVQVGMVGLLGAIRRYDPSFGR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  82 KFEAFLVPTVIGEIKRYLRDKTWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYN 161
Cdd:PRK08583  81 SFEAFAVPTIIGEIKRYLRDKTWSVHVPRRIKELGPKIKKAVDELTTELQRSPKISEIADRLGVSEEEVLEAMEMGKSYQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 162 ALSVDHSIEADKDGSTVTLLDIMGQQDDHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSR 241
Cdd:PRK08583 161 ALSVDHSIEADSDGSTVTLLDIVGQQEDGYELTEQRMILEKILPVLSDREKSIIQCTFIENLSQKETGERLGISQMHVSR 240
                        250
                 ....*....|....*
gi 446963851 242 LQRTAIKKLQEAAHK 256
Cdd:PRK08583 241 LQRQAIKKLREAAFL 255
Sigma_B TIGR02941
RNA polymerase sigma-B factor; This sigma factor is restricted to certain lineages of the ...
2-256 3.60e-153

RNA polymerase sigma-B factor; This sigma factor is restricted to certain lineages of the order Bacillales including Staphylococcus, Listeria, and Bacillus.


Pssm-ID: 131987 [Multi-domain]  Cd Length: 255  Bit Score: 426.62  E-value: 3.60e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851    2 AKESKSANEVSPEQINQWIKEHQENKNTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFER 81
Cdd:TIGR02941   1 MEIQSQPTNLTKEDVIQWIAEFQQNQNGEAQEKLVDHYQNLVYSIAYKYSKGGPMHEDLVQVGMLGLLGAIRRYDYSIGN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   82 KFEAFLVPTVIGEIKRYLRDKTWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYN 161
Cdd:TIGR02941  81 AFEPFAIPTIIGEIKRYLRDKTWSVHVPRRIKELGPKIKKAIDELTDHLQRSPKIIEIADHLGLSEEEVLEIMEMGQSYR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  162 ALSVDHSIEADKDGSTVTLLDIMGQQDDHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSR 241
Cdd:TIGR02941 161 ALSVDDVIEADSDGSTVARLDSVGEVEDGYDQTERRMVLEKILPILSEREKSIIHCTFEENLSQKETGERLGISQMHVSR 240
                         250
                  ....*....|....*
gi 446963851  242 LQRTAIKKLQEAAHK 256
Cdd:TIGR02941 241 LQRQAISKLKEAAFL 255
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
15-253 1.17e-64

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 201.21  E-value: 1.17e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  15 QINQWIKEHQENkNTDAQDKLVKHYQKLIESLAYKYS-KGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIG 93
Cdd:COG1191    1 DLEELLRRYQEG-DEEAREELIEEYLPLVKKIASRLAgRLPAELDDLIQVGLIGLIEAIDRFDPSKGVSFETYAVPRIRG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  94 EIKRYLRDKTWsvhVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEADK 173
Cdd:COG1191   80 AILDYLRDEDW---VPRSVRELARKIEEAIEELEQELGREPTDEEIAEELGISLEEVQEALEAANAYQLLSLDEPLEDGD 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 174 DgstvtLLDIM--GQQDDHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQ 251
Cdd:COG1191  157 D-----LLDLLesGDPEEELEHEELREALAEAIEQLPERERLVLSLYYFEELTLKEIAEVLGVSESRVSRLHKKALARLR 231

                 ..
gi 446963851 252 EA 253
Cdd:COG1191  232 EY 233
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
35-104 1.01e-18

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 77.63  E-value: 1.01e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   35 LVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDKTW 104
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIIDYLRKQRR 70
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
200-251 2.48e-10

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 54.80  E-value: 2.48e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446963851 200 LEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQ 251
Cdd:cd06171    4 LEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
204-256 2.31e-03

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 35.58  E-value: 2.31e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 446963851   204 LPILSDREREIIQCTfIEGLSQKETGERIGLS----QMHVSRLQR-TAIKKLQEAAHK 256
Cdd:smart00421   1 LASLTPREREVLRLL-AEGLTNKEIAERLGISektvKTHLSNIMRkLGVRSRTQAVRL 57
 
Name Accession Description Interval E-value
PRK08583 PRK08583
RNA polymerase sigma factor SigB; Validated
2-256 1.41e-167

RNA polymerase sigma factor SigB; Validated


Pssm-ID: 236306 [Multi-domain]  Cd Length: 257  Bit Score: 463.01  E-value: 1.41e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   2 AKESKSANEVSPEQINQWIKEHQENKNTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFER 81
Cdd:PRK08583   1 MKESSQPTKLTKEEVNKWIAEYQENQDEEAQEKLVKHYKNLVESLAYKYSKGQSHHEDLVQVGMVGLLGAIRRYDPSFGR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  82 KFEAFLVPTVIGEIKRYLRDKTWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYN 161
Cdd:PRK08583  81 SFEAFAVPTIIGEIKRYLRDKTWSVHVPRRIKELGPKIKKAVDELTTELQRSPKISEIADRLGVSEEEVLEAMEMGKSYQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 162 ALSVDHSIEADKDGSTVTLLDIMGQQDDHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSR 241
Cdd:PRK08583 161 ALSVDHSIEADSDGSTVTLLDIVGQQEDGYELTEQRMILEKILPVLSDREKSIIQCTFIENLSQKETGERLGISQMHVSR 240
                        250
                 ....*....|....*
gi 446963851 242 LQRTAIKKLQEAAHK 256
Cdd:PRK08583 241 LQRQAIKKLREAAFL 255
Sigma_B TIGR02941
RNA polymerase sigma-B factor; This sigma factor is restricted to certain lineages of the ...
2-256 3.60e-153

RNA polymerase sigma-B factor; This sigma factor is restricted to certain lineages of the order Bacillales including Staphylococcus, Listeria, and Bacillus.


Pssm-ID: 131987 [Multi-domain]  Cd Length: 255  Bit Score: 426.62  E-value: 3.60e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851    2 AKESKSANEVSPEQINQWIKEHQENKNTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFER 81
Cdd:TIGR02941   1 MEIQSQPTNLTKEDVIQWIAEFQQNQNGEAQEKLVDHYQNLVYSIAYKYSKGGPMHEDLVQVGMLGLLGAIRRYDYSIGN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   82 KFEAFLVPTVIGEIKRYLRDKTWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYN 161
Cdd:TIGR02941  81 AFEPFAIPTIIGEIKRYLRDKTWSVHVPRRIKELGPKIKKAIDELTDHLQRSPKIIEIADHLGLSEEEVLEIMEMGQSYR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  162 ALSVDHSIEADKDGSTVTLLDIMGQQDDHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSR 241
Cdd:TIGR02941 161 ALSVDDVIEADSDGSTVARLDSVGEVEDGYDQTERRMVLEKILPILSEREKSIIHCTFEENLSQKETGERLGISQMHVSR 240
                         250
                  ....*....|....*
gi 446963851  242 LQRTAIKKLQEAAHK 256
Cdd:TIGR02941 241 LQRQAISKLKEAAFL 255
SigBFG TIGR02980
RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; This group of similar sigma-70 factors ...
30-254 3.22e-109

RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.


Pssm-ID: 274373 [Multi-domain]  Cd Length: 227  Bit Score: 314.16  E-value: 3.22e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   30 DAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDKTWSVHVP 109
Cdd:TIGR02980   3 EAREKLVELNLPLVRSIARRFRNRGEPHEDLVQVGTIGLVKAIDRFDPSYGVKFSTFAVPTIMGEIKRFFRDDTWAVRVP 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  110 RRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEADkDGSTVTLLDIMGQQDD 189
Cdd:TIGR02980  83 RRLKELGVKINKATEELTQRLGRSPTIAEIAERLGVSEEEVVEALEAGNAYQALSLDASIEDD-DGDPIALLDTLGDEDD 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446963851  190 HYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQEAA 254
Cdd:TIGR02980 162 ALETVEDRLALKPLLAALPERERRILLLRFFEDKTQSEIAERLGISQMHVSRLLRRALKKLREQL 226
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
15-253 1.17e-64

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 201.21  E-value: 1.17e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  15 QINQWIKEHQENkNTDAQDKLVKHYQKLIESLAYKYS-KGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIG 93
Cdd:COG1191    1 DLEELLRRYQEG-DEEAREELIEEYLPLVKKIASRLAgRLPAELDDLIQVGLIGLIEAIDRFDPSKGVSFETYAVPRIRG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  94 EIKRYLRDKTWsvhVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEADK 173
Cdd:COG1191   80 AILDYLRDEDW---VPRSVRELARKIEEAIEELEQELGREPTDEEIAEELGISLEEVQEALEAANAYQLLSLDEPLEDGD 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 174 DgstvtLLDIM--GQQDDHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQ 251
Cdd:COG1191  157 D-----LLDLLesGDPEEELEHEELREALAEAIEQLPERERLVLSLYYFEELTLKEIAEVLGVSESRVSRLHKKALARLR 231

                 ..
gi 446963851 252 EA 253
Cdd:COG1191  232 EY 233
PRK07122 PRK07122
RNA polymerase sigma factor SigF; Reviewed
32-252 1.10e-50

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 168831 [Multi-domain]  Cd Length: 264  Bit Score: 166.49  E-value: 1.10e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  32 QDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDKTWSVHVPRR 111
Cdd:PRK07122  42 RDRIVTRCLPLADHIARRFDGRGEPRDDLVQVARVGLVNAVNRFDVETGSDFVSFAVPTIMGEVRRHFRDNSWSVKVPRR 121
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 112 IKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEADKDGsTVTLLDIMGQQDDHY 191
Cdd:PRK07122 122 LKELHLRLGRATAELSQRLGRAPTASELAAELGMDREEVVEGLVAGSAYNTLSIDSGGGSGDDD-ARAIADTLGDVDAGL 200
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446963851 192 DLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQE 252
Cdd:PRK07122 201 DQIENREALRPLLAALPERERTVLVLRFFESMTQTQIAERVGISQMHVSRLLAKTLARLRD 261
spore_sigF TIGR02885
RNA polymerase sigma-F factor; Members of this protein family are the RNA polymerase sigma ...
20-252 9.54e-44

RNA polymerase sigma-F factor; Members of this protein family are the RNA polymerase sigma factor F. Sigma-F is specifically and universally a component of the Firmicutes lineage endospore formation program, and is expressed in the forespore to turn on expression of dozens of genes. It is closely homologous to sigma-G, which is also expressed in the forespore. [Transcription, Transcription factors, Cellular processes, Sporulation and germination]


Pssm-ID: 131931 [Multi-domain]  Cd Length: 231  Bit Score: 147.55  E-value: 9.54e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   20 IKEHQENkNTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYL 99
Cdd:TIGR02885   2 IKLAQNG-DKEARDKLIECNLRLVWSIVKRFLNRGYEPEDLFQIGCIGLVKAIDKFDLSYDVKFSTYAVPMIMGEIKRFL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  100 RDKTwSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALsvdHSIEADKDGSTVT 179
Cdd:TIGR02885  81 RDDG-IIKVSRSLKELARKIRYMKEELSKELGREPTINELAEALGVSPEEIVMALESARSPQSL---YDTVHQDDGDPIY 156
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446963851  180 LLDIMGQQDDHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQE 252
Cdd:TIGR02885 157 LLDQIADKGSEDSDWLEKIALKEAISKLDERERQIIMLRYFKDKTQTEVANMLGISQVQVSRLEKKVLKKMKE 229
PRK05572 PRK05572
RNA polymerase sporulation sigma factor, SigF/SigG family;
3-252 9.81e-42

RNA polymerase sporulation sigma factor, SigF/SigG family;


Pssm-ID: 180137 [Multi-domain]  Cd Length: 252  Bit Score: 143.19  E-value: 9.81e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   3 KESKSANEVSPEQINQWIKEHQENkNTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERK 82
Cdd:PRK05572   6 KNKKKKPQLKDEENKELIKKSQDG-DQEARDTLVEKNLRLVWSVVQRFLNRGYEPDDLFQIGCIGLLKAVDKFDLSYDVK 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  83 FEAFLVPTVIGEIKRYLRDKTwSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEmgqSYNA 162
Cdd:PRK05572  85 FSTYAVPMIIGEIQRFLRDDG-TVKVSRSLKETANKIRKDKDELSKELGREPTIEELAEYLGVTPEEVVLAQE---ASRS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 163 LSVDHSIEADKDGSTVTLLDIMGQQDDHyDLTEKrMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRL 242
Cdd:PRK05572 161 PQSIHETVHENDGDPITLLDQIADQSEE-DWFDK-IALKEAIRELDERERLIVYLRYFKDKTQSEVAKRLGISQVQVSRL 238
                        250
                 ....*....|
gi 446963851 243 QRTAIKKLQE 252
Cdd:PRK05572 239 EKKILKQMKE 248
PRK07408 PRK07408
RNA polymerase sigma factor SigF; Reviewed
15-252 2.17e-40

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 180965 [Multi-domain]  Cd Length: 256  Bit Score: 139.67  E-value: 2.17e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  15 QINQWIKEHQENKNTDAQDKLVKHYQKLIESLAYKYSkGQSH--HEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVI 92
Cdd:PRK07408  10 ETMELLRAYQQNPSIALRNQLVELNLGLVRKEAHRWS-NQCSepYEDLVQVGSLGLIRAIERFDPSKGHAFSSFAIPYIR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  93 GEIKRYLRDKTWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEAD 172
Cdd:PRK07408  89 GEIQHYLRDKSPTVRIPRRWQELQRQAKKVRQELRQELGRQPTDQEIAQALDISLEEWQEIKLALQNRTPLSLDAPVNQD 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 173 KDGSTvTLLDIMgqQDDHYDL----TEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIK 248
Cdd:PRK07408 169 EDGST-SLGDLL--PDPRYRSfqlaQEDRIRLQQALAQLEERTREVLEFVFLHDLTQKEAAERLGISPVTVSRRVKKGLD 245

                 ....
gi 446963851 249 KLQE 252
Cdd:PRK07408 246 QLKK 249
PRK08215 PRK08215
RNA polymerase sporulation sigma factor SigG;
25-251 1.08e-32

RNA polymerase sporulation sigma factor SigG;


Pssm-ID: 181296 [Multi-domain]  Cd Length: 258  Bit Score: 119.67  E-value: 1.08e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  25 ENKNTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDKTw 104
Cdd:PRK08215  32 QNGDKEAREKLINGNLRLVLSVIQRFNNRGENVDDLFQVGCIGLMKAIDNFDLSQNVKFSTYAVPMIIGEIRRYLRDNN- 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 105 SVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSynALSVDHSIEADkDGSTVTLLDIM 184
Cdd:PRK08215 111 PIRVSRSLRDIAYKALQVREKLINENSKEPTVEEIAKELEVPREEVVFALDAIQD--PVSLFEPIYHD-GGDPIYVMDQI 187
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446963851 185 GQQDDHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQ 251
Cdd:PRK08215 188 SDEKNKDENWLEEIALKEAMKKLNDREKLILNLRFFQGKTQMEVAEEIGISQAQVSRLEKAALKHMR 254
FliA_WhiG TIGR02479
RNA polymerase sigma factor, FliA/WhiG family; Most members of this family are the flagellar ...
35-252 3.25e-27

RNA polymerase sigma factor, FliA/WhiG family; Most members of this family are the flagellar operon sigma factor FliA, controlling transcription of bacterial flagellar genes by RNA polymerase. An exception is the sigma factor WhiG in the genus Streptomyces, involved in the production of sporulating aerial mycelium.


Pssm-ID: 274153 [Multi-domain]  Cd Length: 224  Bit Score: 104.66  E-value: 3.25e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   35 LVKHYQKLIESLAYKYSKGQSHH---EDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDKTWsvhVPRR 111
Cdd:TIGR02479   1 LIRRYLPLVKRIAGRLSVGLPSSvelDDLIQAGMFGLLDAIERYDPSRGAKFETYAVQRIRGAMLDELRRLDW---VPRS 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  112 IKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEADKDGSTVTLL---DIMGQQD 188
Cdd:TIGR02479  78 LRQKARKLERAIRELEARLGREPTEEEIAEELGMDLKEYRQALNEINALSLVSLDELLESGDDGGSLIDRiedDKSEDPE 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446963851  189 DHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQE 252
Cdd:TIGR02479 158 EELEREELREALAEAIESLSEREQLVLSLYYYEELNLKEIGEVLGLTESRVSQIHSQALKKLRA 221
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
30-253 2.25e-23

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 92.41  E-value: 2.25e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   30 DAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMsfERKFEAFLVPTVIGEIKRYLRDKTWsvhvp 109
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDP--EGSFKAWLFRIARNLILDYLRRKRR----- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  110 rrikeigprIKKVSDELTAELERSPSIseiadrlevseeevleamemgqsynalsvdhsieadkdgstvtlldimgqqDD 189
Cdd:TIGR02937  74 ---------LRRELDLLEELLDSDPSP---------------------------------------------------EE 93
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446963851  190 HYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQEA 253
Cdd:TIGR02937  94 ELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRARKKLREL 157
PRK06288 PRK06288
RNA polymerase sigma factor WhiG; Reviewed
2-250 9.02e-20

RNA polymerase sigma factor WhiG; Reviewed


Pssm-ID: 235770 [Multi-domain]  Cd Length: 268  Bit Score: 85.51  E-value: 9.02e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   2 AKESKSANEVSPEQINQWIKEHQENKNTDAQDKLVKHYQKLIESLAYKYSKGQSHH---EDLVQVGMVGLIGAINRFDMS 78
Cdd:PRK06288   3 KKMSGKIPKYAQQDETELWREYKKTGDPKIREYLILKYSPLVKYVAGRIAVGMPQNvefDDLVSYGVFGLIDAIEKFDPE 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  79 FERKFEAFLVPTVIGEIKRYLRDKTWsvhVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQ 158
Cdd:PRK06288  83 REIKFKTYAVTRIRGAIFDELRSIDW---IPRSVRQKARQIERAIAMLEARLGRTPSDEEIADELGISLEEYNSLLSKLS 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 159 SYNALSVDHSIEADKDGSTVTLLDIM--GQQDDHYDLTEKRMILEKI---LPILSDREREIIQCTFIEGLSQKETGERIG 233
Cdd:PRK06288 160 GTSVVSLNDLWFGGDEGDEVSLMDTLesPAALNPDEIAEREEIKRVIveaIKTLPEREKKVLILYYYEDLTLKEIGKVLG 239
                        250
                 ....*....|....*..
gi 446963851 234 LSQMHVSRLQRTAIKKL 250
Cdd:PRK06288 240 VTESRISQLHTKAVLQL 256
PRK07670 PRK07670
FliA/WhiG family RNA polymerase sigma factor;
17-256 4.47e-19

FliA/WhiG family RNA polymerase sigma factor;


Pssm-ID: 181075 [Multi-domain]  Cd Length: 251  Bit Score: 83.56  E-value: 4.47e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  17 NQWIKEHQEnkntDAQDKLVKHYQKLIESLAYKYSKG---QSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIG 93
Cdd:PRK07670  13 DRWKEERDP----DAADELIRRYMPLVHYHVQRISVGlpkSVSKDDLKSLGMLGLYDALEKFDPSRDLKFDTYASFRIRG 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  94 EIKRYLRDKTWsvhVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEADK 173
Cdd:PRK07670  89 AIIDGLRKEDW---LPRSMREKTKKVEAAIEKLEQRYMRNVTPKEVAAELGMTEEEVEATMNEGFFANLLSIDEKTHDQD 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 174 DGSTVTLLDImgqqDDHYDLTEKRMI-------LEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTA 246
Cdd:PRK07670 166 DGENVSVTIR----DDKTPTPEEKLLkeelieeLAEKIKQLSEKEQLVISLFYKEELTLTEIGQVLNLSTSRISQIHSKA 241
                        250
                 ....*....|
gi 446963851 247 IKKLQEAAHK 256
Cdd:PRK07670 242 LFKLKKLLEK 251
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
35-104 1.01e-18

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 77.63  E-value: 1.01e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   35 LVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDKTW 104
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIIDYLRKQRR 70
fliA PRK06986
flagellar biosynthesis sigma factor; Validated
58-252 5.40e-17

flagellar biosynthesis sigma factor; Validated


Pssm-ID: 235901 [Multi-domain]  Cd Length: 236  Bit Score: 77.58  E-value: 5.40e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  58 EDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDKTWsvhVPRRIKEIGPRIKKVSDELTAELERSPSIS 137
Cdd:PRK06986  39 DDLIQAGMIGLLEAARRYDGEQGASFETYAGQRIRGAMLDELRSLDW---VPRSVRRNAREVAQAIRQLEQELGREPTDT 115
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 138 EIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEADKDGSTVTLLDimgQQDDHYDLTEK---RMILEKILPILSDREREI 214
Cdd:PRK06986 116 EVAEKLGLSLEEYREMLLDTNISQLFSIDELRGEHGDSILVTEDH---QDEDPLQQLEDeelREALVEAIESLPEREQLV 192
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 446963851 215 IQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQE 252
Cdd:PRK06986 193 LSLYYQEELNLKEIGAVLGVSESRVSQIHSQAIKRLRA 230
RpoD COG0568
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
25-256 1.78e-16

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 76.63  E-value: 1.78e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  25 ENKNTDAQDKLVKHYQKLIESLAYKYS-KGQSHhEDLVQVGMVGLIGAINRFDMSFERKF--------EAflvptvigEI 95
Cdd:COG0568   25 QAGDEEAKRKLVEANLRLVVSIAKKYQgRGLPL-LDLIQEGNLGLMKAVEKFDPERGFRFstyatwwiRQ--------AI 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  96 KRYLRDKtWS-----VHVPRRIKeigpRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQsyNALSVDHSIE 170
Cdd:COG0568   96 TRAIADQ-WRtirlpVHMAETLN----KLRRAKRQLLQELGREPTPEEIAEELGVPEEKVREMLRLAR--EPVSLDAPVG 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 171 ADKDGstvTLLDI-----MGQQDDHYDLTEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGlSQMHVSR---- 241
Cdd:COG0568  169 DDEDS---ELGDLledeeAPSPEEALEEELLREELREALDTLTEREREILRLRFGLDDGEPHTLEEIG-KEFGVSRervr 244
                        250
                 ....*....|....*.
gi 446963851 242 -LQRTAIKKLQEAAHK 256
Cdd:COG0568  245 qIEAKALRKLRHPLRS 260
PRK05911 PRK05911
RNA polymerase sigma factor sigma-28; Reviewed
25-253 1.58e-15

RNA polymerase sigma factor sigma-28; Reviewed


Pssm-ID: 235644 [Multi-domain]  Cd Length: 257  Bit Score: 73.88  E-value: 1.58e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  25 ENKNTDAQDKLVKHYQKLIESLAYKYSKGQSHH---EDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRD 101
Cdd:PRK05911  18 STQEIEYRDVLIEFYLPLVKNVAHRLISGMPSHvktEDLYASGVEGLVRAVERFDPEKSRRFEGYALFLIKAAIIDDLRK 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 102 KTWsvhVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEA-DKDGSTVTL 180
Cdd:PRK05911  98 QDW---VPRSVHQKANKLADAMDSLRQSLGKEPTDGELCEYLNISQQELSGWFSSARPALILSLNEEFPCqSDDEAGLAL 174
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446963851 181 LDIMGQQ--DDHYDLTEKR---MILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQEA 253
Cdd:PRK05911 175 EERIADEraETGYDVVDKKefsSILAEAILALEEKERKVMALYYYEELVLKEIGKILGVSESRVSQIHSKALLKLRAT 252
PRK05803 PRK05803
RNA polymerase sporulation sigma factor SigK;
31-250 6.36e-15

RNA polymerase sporulation sigma factor SigK;


Pssm-ID: 180266 [Multi-domain]  Cd Length: 233  Bit Score: 71.90  E-value: 6.36e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  31 AQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDktwsvhvpr 110
Cdd:PRK05803  50 ARNILIERNLRLVAHIVKKFENTGEDVDDLISIGTIGLIKAIESFDAGKGTKLATYAARCIENEILMHLRN--------- 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 111 rikeigprIKKVSDELtaelerspsiseiadrlevseeevleamemgqsynalSVDHSIEADKDGSTVTLLDIMG-QQDD 189
Cdd:PRK05803 121 --------LKKTKKEV-------------------------------------SLQDPIGVDKEGNEISLIDILGsEEDD 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 190 HYDLTEKRMILEKI---LPILSDREREIIQCTFieGL------SQKETGERIGLSQMHVSRLQRTAIKKL 250
Cdd:PRK05803 156 VIEQVELKMEVEKLykkIDILDEREKEVIEMRY--GLgngkekTQREIAKALGISRSYVSRIEKRALKKL 223
PRK05949 PRK05949
RNA polymerase sigma factor; Validated
3-251 9.74e-13

RNA polymerase sigma factor; Validated


Pssm-ID: 180321 [Multi-domain]  Cd Length: 327  Bit Score: 66.79  E-value: 9.74e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   3 KESKSANEVSPEQINQWIKEHQEnkntdAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERK 82
Cdd:PRK05949  69 PEWAEAVNLSETELKQTLKQGKR-----AKQKMIEANLRLVVAIAKKYQKRNMEFLDLIQEGTLGLERGVEKFDPTRGYK 143
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  83 FEAFLVPTVIGEIKRYLRDKTWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQsyNA 162
Cdd:PRK05949 144 FSTYAYWWIRQAITRAIAQQARTIRLPIHITEKLNKIKKTQRELSQKLGRSATPAEIAKELELEPSQIREYLSMAR--QP 221
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 163 LSVDHSIEADKDGSTVTLLDIMGQQDDHYDLTEK-RMILEKILPILSDREREIIQCTF----IEGLSQKETGERIGLSQM 237
Cdd:PRK05949 222 ISLDVRVGDNQDTELSELLEDEGPSPDQYITQELlRQDLNNLLAELTPQQREVLTLRFgledGKELSLAKVGERLNLSRE 301
                        250
                 ....*....|....
gi 446963851 238 HVSRLQRTAIKKLQ 251
Cdd:PRK05949 302 RVRQLEHQALAHLR 315
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
204-252 3.65e-12

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 59.36  E-value: 3.65e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 446963851  204 LPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQE 252
Cdd:pfam04545   2 LASLPPRERQVLVLRYGEGLTLEEIGERLGISRERVRQIEKRALRKLRK 50
PRK07405 PRK07405
RNA polymerase sigma factor SigD; Validated
4-253 2.42e-11

RNA polymerase sigma factor SigD; Validated


Pssm-ID: 180963 [Multi-domain]  Cd Length: 317  Bit Score: 62.47  E-value: 2.42e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851   4 ESKSANEVSPEQINQWIKEHQEnkntdAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKF 83
Cdd:PRK07405  60 EWAKAAKLSEEELRSAIAEGEA-----AKRKMVEANLRLVVSVAKKYLKRNVDLLDLIQEGTIGMQRGVEKFDPTKGYRF 134
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  84 EAFLVPTVIGEIKRYLRDKTWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEmgQSYNAL 163
Cdd:PRK07405 135 STYAYWWIRQAITRAIAEKSRTIRLPIHITEKLNKIKKAQRQLSQQLGRAATIGELAEELELTPKQVREYLE--RARQPL 212
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 164 SVDHSIEADKDGSTVTLLDIMGQQDDHYDL-TEKRMILEKILPILSDREREIIQCTF--IEG--LSQKETGERIGLSQMH 238
Cdd:PRK07405 213 SLDLRVGDNQDTELGELLEDTGASPEDFATqSSLQLDLERLMEDLTPQQKEVIALRFglEDGqpLTLAKIGERLNISRER 292
                        250
                 ....*....|....*
gi 446963851 239 VSRLQRTAIKKLQEA 253
Cdd:PRK07405 293 VRQIEREALSKLRKR 307
PRK07406 PRK07406
RNA polymerase sigma factor RpoD; Validated
31-156 3.80e-11

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 236012 [Multi-domain]  Cd Length: 373  Bit Score: 62.11  E-value: 3.80e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  31 AQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDKTWSVHVPR 110
Cdd:PRK07406 137 AKEKMVQSNLRLVVSIAKKYMNRGLSFQDLIQEGSLGLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQSRTIRLPV 216
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 446963851 111 RIKEIGPRIKKVSDELTAELERSPSISEIADRlevseeevleaMEM 156
Cdd:PRK07406 217 HLYETISRIKKTTKVLSQEFGRKPTEEEIAES-----------MEM 251
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
28-253 1.21e-10

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 58.85  E-value: 1.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  28 NTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDmsFERKFEAFLVPTVIGEIKRYLRDKTwsvh 107
Cdd:COG1595   15 DEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFR--GRGSFRAWLYRIARNLAIDHLRKRR---- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 108 vprrikeigpRIKKVSDELTAELERSpsiseiadrlevseeevleamemgqsynALSVDHSIEADkdgstvtlldimgqq 187
Cdd:COG1595   89 ----------RRRELLDELAEELPDE----------------------------AADPEEALEAE--------------- 115
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446963851 188 ddhydltEKRMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHV-SRLQRtAIKKLQEA 253
Cdd:COG1595  116 -------ELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVkSRLSR-ARKKLREA 174
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
200-251 2.48e-10

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 54.80  E-value: 2.48e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446963851 200 LEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQ 251
Cdd:cd06171    4 LEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
Sigma70_r3 pfam04539
Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the ...
114-188 5.04e-09

Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the sigma-factor. Region is not normally involved in the recognition of promoter DNA, but as some specific bacterial promoters containing an extended -10 promoter element, residues within region 3 play an important role. Region 3 primarily is involved in binding the core RNA polymerase in the holoenzyme.


Pssm-ID: 427997 [Multi-domain]  Cd Length: 78  Bit Score: 51.84  E-value: 5.04e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446963851  114 EIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEADKD-GSTVTLLDIMGQQD 188
Cdd:pfam04539   1 ELLNKIKRAQRELEQELGREPTPEEIAEELGLSPEKVREVLEAAREPVSLDTPVGEEEDGElGDLLEDDDIESPEE 76
PRK07598 PRK07598
RNA polymerase sigma factor SigC; Validated
10-252 7.98e-09

RNA polymerase sigma factor SigC; Validated


Pssm-ID: 236067 [Multi-domain]  Cd Length: 415  Bit Score: 55.65  E-value: 7.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  10 EVSPEQINQWIKEHQEnkntdAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVP 89
Cdd:PRK07598 160 KLTVEELEQIQKQGLR-----AKEHMIKANLRLVVSVAKKYQNRGLELLDLVQEGTLGLERAVEKFDPTKGYRFSTYAYW 234
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  90 TVIGEIKRYLRDKTWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEmgQSYNALSVDHSI 169
Cdd:PRK07598 235 WIRQGITRAIATQSRTIRLPVHITEKLNKIKKAQRKISQEKGRTPTIEDIAQELEMTPTQVREVLL--RVPRSVSLETKV 312
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 170 EADKDGSTVTLLDIMGQQDDHYDLTEK-RMILEKILPILSDREREIIQCTFieGL------SQKETGERIGLSQMHVSRL 242
Cdd:PRK07598 313 GKDKDTELGDLLETDDISPEEMLMRESlQRDLQHLLADLTSRERDVIRMRF--GLadghtySLAEIGRALDLSRERVRQI 390
                        250
                 ....*....|
gi 446963851 243 QRTAIKKLQE 252
Cdd:PRK07598 391 ESKALQKLRQ 400
PRK08301 PRK08301
RNA polymerase sporulation sigma factor SigE;
58-256 9.88e-09

RNA polymerase sporulation sigma factor SigE;


Pssm-ID: 236228 [Multi-domain]  Cd Length: 234  Bit Score: 54.09  E-value: 9.88e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  58 EDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRdktwsvhvprrikeigpRIKKVSDELtaelerspsis 137
Cdd:PRK08301  80 EDLISIGTIGLIKAVNTFNPEKKIKLATYASRCIENEILMYLR-----------------RNNKVKAEV----------- 131
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 138 eiadrlevseeevleamemgqsynalSVDHSIEADKDGSTVTLLDIMGQQDD--HYDLTEK--RMILEKILPILSDRERE 213
Cdd:PRK08301 132 --------------------------SFDEPLNIDWDGNELLLSDVLGTDNDiiYKDIEDEvdRKLLKKALKKLSDREKQ 185
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446963851 214 IIQCTFieGLS------QKETGERIGLSQMHVSRLQRTAIKKLQEAAHK 256
Cdd:PRK08301 186 IMELRF--GLNggeektQKEVADMLGISQSYISRLEKRIIKRLKKEINK 232
PRK08295 PRK08295
RNA polymerase sporulation sigma factor SigH;
28-233 6.43e-08

RNA polymerase sporulation sigma factor SigH;


Pssm-ID: 181361 [Multi-domain]  Cd Length: 208  Bit Score: 51.45  E-value: 6.43e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  28 NTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDKTWSVH 107
Cdd:PRK08295  22 DKEALEYLIEKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDYDKDKLSSFKSFAELCITRQIITAIKTANRQKH 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 108 VPrrikeigprikkvsdeLTaelerspsiseiadrlevseeevleamemgqsyNALSVDHSIEADKDGStvTLLDIMGQ- 186
Cdd:PRK08295 102 IP----------------LN---------------------------------SYVSLDKPIYDEESDR--TLLDVISEa 130
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446963851 187 --QDDHYDL---TEKRMILEKILPILSDREREIIQcTFIEGLSQKETGERIG 233
Cdd:PRK08295 131 kvTDPEELIiskEELEDIEEKIEELLSELEKEVLE-LYLDGKSYQEIAEELN 181
PRK07921 PRK07921
RNA polymerase sigma factor SigB; Reviewed
31-252 6.09e-07

RNA polymerase sigma factor SigB; Reviewed


Pssm-ID: 181169 [Multi-domain]  Cd Length: 324  Bit Score: 49.73  E-value: 6.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  31 AQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDKTWSVHVPR 110
Cdd:PRK07921  87 ARRHLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYTKGFKFSTYATWWIRQAITRGMADQSRTIRLPV 166
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 111 RIKEIGPRIKKVSDELTAELERSPSISEIAdrLEVSEEEVLEAMEMGQSYNALSVDHSIEADKD---GSTVTLLDIMgQQ 187
Cdd:PRK07921 167 HLVEQVNKLARIKRELHQQLGREATDEELA--EESGIPEEKIADLLEHSRDPVSLDMPVGSDEEaplGDFIEDSEAT-SA 243
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446963851 188 DDHYDLTEKRMILEKILPILSDREREIIQCTFieGLSQ------KETGERIGLSQMHVSRLQRTAIKKLQE 252
Cdd:PRK07921 244 ENAVIAGLLHTDIRSVLATLDEREQQVIRLRF--GLDDgqprtlDQIGKLFGLSRERVRQIEREVMSKLRN 312
PRK12427 PRK12427
FliA/WhiG family RNA polymerase sigma factor;
24-252 8.50e-06

FliA/WhiG family RNA polymerase sigma factor;


Pssm-ID: 183523 [Multi-domain]  Cd Length: 231  Bit Score: 45.62  E-value: 8.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  24 QENKNTDAQDKLVKhyqKLIESLAYKYSkGQSHHEDLVQVGMVGLIGAINRFDMSFErKFEAFLVPTVIGEIKRYLRDKT 103
Cdd:PRK12427  16 EEGKYLNAYLPLVK---KVVRQLAFQAD-SVIDREDMEQIALMGLLEALRRYGHPDE-QFAAYAVHRIRGAILDELRELD 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 104 WSvhvPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSYNALSVDHSIEADKDGstvtllDI 183
Cdd:PRK12427  91 WR---PRRLRQKTHKTNDAIREIAKRLGHEPNFEEISAELNLTAEEYQEYLLLENAGTLESLDELLALEAHN------DI 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446963851 184 MGQQDDHYDLTEKRMiLEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQE 252
Cdd:PRK12427 162 LQSRDLEENIIIEDN-LKQALSQLDEREQLILHLYYQHEMSLKEIALVLDLTEARICQLNKKIAQKIKS 229
rpoH2 PRK07500
RNA polymerase factor sigma-32; Reviewed
25-253 1.24e-05

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 236033 [Multi-domain]  Cd Length: 289  Bit Score: 45.41  E-value: 1.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  25 ENKNTDAQDKLVKHYQKLIESLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRY-LRDkt 103
Cdd:PRK07500  35 DHRDEDALHRIISAHMRLVISMAGKFRRFGLPMNDLIQEGYVGLLEAAARFEPDREVRFSTYATWWIRASIQDYiLRN-- 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 104 WSVhVP--------------RRIKeigPRIKKVSDELT-AELERspsisEIADRLEVSEEEVLEaMEMGQSYNALSVDHS 168
Cdd:PRK07500 113 WSI-VRggtssaqkalffnlRRLR---ARLAQADEELTkQEIHR-----EIATALGVSLSDVEM-MDARLSGPDASLNAP 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 169 IEADKDGSTV---TLLDIMGQQD----DHYDLTEKRMILEKILPILSDREREIIQCTFI--EGLSQKETGERIGLSQMHV 239
Cdd:PRK07500 183 QSEEDEGRSErmdFLVDDSPLPDeqveSSIDGERRRRWLTQALQTLNERELRIIRERRLreDGATLEALGEELGISKERV 262
                        250
                 ....*....|....
gi 446963851 240 SRLQRTAIKKLQEA 253
Cdd:PRK07500 263 RQIEARALEKLRRA 276
PRK05657 PRK05657
RNA polymerase sigma factor RpoS; Validated
40-252 6.74e-05

RNA polymerase sigma factor RpoS; Validated


Pssm-ID: 235548 [Multi-domain]  Cd Length: 325  Bit Score: 43.41  E-value: 6.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851  40 QKLIES---LAYKYSKGQSHHE----DLVQVGMVGLIGAINRFDMsfERKFeaflvptvigeikRYLRDKTW-------- 104
Cdd:PRK05657  89 QRMIESnlrLVVKIAKRYLNRGlallDLIEEGNLGLIRAVEKFDP--ERGF-------------RFSTYATWwirqtier 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 105 -----------SVHVprrIKEIGP--RIKKvsdELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSynALSVDHSIEA 171
Cdd:PRK05657 154 aimnqtrtirlPVHV---VKELNVylRAAR---ELEHKLDHEPSAEEIAELLDKPVDDVSRMLALNER--ITSLDTPLGG 225
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446963851 172 DkdgSTVTLLDIMgqQDDHY----DLTEKR---MILEKILPILSDREREIIQCTF----IEGLSQKETGERIGLSQMHVS 240
Cdd:PRK05657 226 D---PEKSLLDIL--ADEQEngpeDTTQDDdmkQSIVKWLFELNDKQREVLARRFgllgYEAATLEDVAREIGLTRERVR 300
                        250
                 ....*....|..
gi 446963851 241 RLQRTAIKKLQE 252
Cdd:PRK05657 301 QIQVEALRRLRE 312
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
178-244 4.76e-04

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 39.11  E-value: 4.76e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446963851 178 VTLLDIMGQQDDHYDLTEKrmilekilpILSDREREIIQCtFIEGLSQKETGERIGLSQ----MHVSRLQR 244
Cdd:COG2197   50 VVLLDIRMPGMDGLEALRR---------LLTPREREVLRL-LAEGLSNKEIAERLGISErtvkTHVSNILR 110
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
197-250 1.75e-03

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 35.51  E-value: 1.75e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 446963851  197 RMILEKILPILSDREREIIQCTFIEGLSQKETGERIGLSQMHV-SRLQRtAIKKL 250
Cdd:pfam08281   1 LEALLRALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVkSRLSR-ARKKL 54
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
204-256 2.31e-03

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 35.58  E-value: 2.31e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 446963851   204 LPILSDREREIIQCTfIEGLSQKETGERIGLS----QMHVSRLQR-TAIKKLQEAAHK 256
Cdd:smart00421   1 LASLTPREREVLRLL-AEGLTNKEIAERLGISektvKTHLSNIMRkLGVRSRTQAVRL 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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