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Conserved domains on  [gi|446922456|ref|WP_000999712|]
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aromatic acid exporter family protein [Staphylococcus aureus]

Protein Classification

FUSC family protein( domain architecture ID 11467894)

FUSC family protein containing a fusaric acid resistance protein (FUSC_2) domain; may be involved in membrane transport

Gene Ontology:  GO:0055085|GO:0022857|GO:0005886
PubMed:  1370369

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
1-201 5.83e-40

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


:

Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 138.97  E-value: 5.83e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456   1 MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLT-PIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFG 79
Cdd:COG4129    1 MKRRRALRRIGLRTLKTALAAALAWLIAELLGLPyPFFAAIAAVLCLQPTVGRSLRRALERILGVLIGALVGVLFFLLLG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456  80 DqSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLA-MIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQV 158
Cdd:COG4129   81 Y-GPWQLGLAVLLAILLAVLLKLGEGIVLAAVTALLvLLLGSPDDSLGYALNRLLDTLIGVGVALLVNLLLLPPDPERRL 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 446922456 159 EEKLSKTDALMYKLFynrcqELILSRLQSDKSEKAYKNIFNLN 201
Cdd:COG4129  160 RRAAAELLEELADIL-----RELLRLRDASDAEEALKRLRELQ 197
 
Name Accession Description Interval E-value
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
1-201 5.83e-40

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 138.97  E-value: 5.83e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456   1 MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLT-PIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFG 79
Cdd:COG4129    1 MKRRRALRRIGLRTLKTALAAALAWLIAELLGLPyPFFAAIAAVLCLQPTVGRSLRRALERILGVLIGALVGVLFFLLLG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456  80 DqSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLA-MIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQV 158
Cdd:COG4129   81 Y-GPWQLGLAVLLAILLAVLLKLGEGIVLAAVTALLvLLLGSPDDSLGYALNRLLDTLIGVGVALLVNLLLLPPDPERRL 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 446922456 159 EEKLSKTDALMYKLFynrcqELILSRLQSDKSEKAYKNIFNLN 201
Cdd:COG4129  160 RRAAAELLEELADIL-----RELLRLRDASDAEEALKRLRELQ 197
ArAE_1 pfam06081
Aromatic acid exporter family member 1; This family consists of bacterial proteins with three ...
10-148 9.15e-31

Aromatic acid exporter family member 1; This family consists of bacterial proteins with three transmembrane regions that are purported to be aromatic acid exporters.


Pssm-ID: 428756 [Multi-domain]  Cd Length: 141  Bit Score: 113.04  E-value: 9.15e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456   10 IGARTIKTGIAIFLTAVFCMALDL-TPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGdQSPFTYAL 88
Cdd:pfam06081   3 IGYRTLKTAIAVTLAIIIAELLGLpYPVSAGIIAILCIQPTKKRSLRTALARFQACVIGAIIAVVFFELFG-YHPFSIGL 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456   89 SATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYiFNFLSRTLTAIIGLVTSGLINFM 148
Cdd:pfam06081  82 FLLLFIPLTVKLKLEEGIVVSSVTVIHLLESKSISF-FLILNELLLITIGIGVALLVNLY 140
 
Name Accession Description Interval E-value
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
1-201 5.83e-40

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 138.97  E-value: 5.83e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456   1 MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLT-PIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFG 79
Cdd:COG4129    1 MKRRRALRRIGLRTLKTALAAALAWLIAELLGLPyPFFAAIAAVLCLQPTVGRSLRRALERILGVLIGALVGVLFFLLLG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456  80 DqSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLA-MIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQV 158
Cdd:COG4129   81 Y-GPWQLGLAVLLAILLAVLLKLGEGIVLAAVTALLvLLLGSPDDSLGYALNRLLDTLIGVGVALLVNLLLLPPDPERRL 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 446922456 159 EEKLSKTDALMYKLFynrcqELILSRLQSDKSEKAYKNIFNLN 201
Cdd:COG4129  160 RRAAAELLEELADIL-----RELLRLRDASDAEEALKRLRELQ 197
ArAE_1 pfam06081
Aromatic acid exporter family member 1; This family consists of bacterial proteins with three ...
10-148 9.15e-31

Aromatic acid exporter family member 1; This family consists of bacterial proteins with three transmembrane regions that are purported to be aromatic acid exporters.


Pssm-ID: 428756 [Multi-domain]  Cd Length: 141  Bit Score: 113.04  E-value: 9.15e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456   10 IGARTIKTGIAIFLTAVFCMALDL-TPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGdQSPFTYAL 88
Cdd:pfam06081   3 IGYRTLKTAIAVTLAIIIAELLGLpYPVSAGIIAILCIQPTKKRSLRTALARFQACVIGAIIAVVFFELFG-YHPFSIGL 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456   89 SATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYiFNFLSRTLTAIIGLVTSGLINFM 148
Cdd:pfam06081  82 FLLLFIPLTVKLKLEEGIVVSSVTVIHLLESKSISF-FLILNELLLITIGIGVALLVNLY 140
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
15-246 4.43e-15

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 74.28  E-value: 4.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456  15 IKTGIAIFLTAVFCMALDLT-PIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFT 93
Cdd:COG1289   51 LRLALAALLALLIALLLGLPhPYWALLTVLIVLQPSYGATLSRALQRILGTLLGALAGLLLLALFPQPLLLLLALALVLG 130
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456  94 ILFCTKLKLQVGTNVAVLTSLAMI-PGIHDAYIFNF-LSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYK 171
Cdd:COG1289  131 LCFFALLTRSYAFALAGITAAVVLlFALLGPGVFDVaLARVLDTLIGILIALLVSYLLWPRWARRRLRARLARALRANAR 210
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446922456 172 LFynrcqELILSRLQSDKS---EKAYKNIFNLNNQVETLISYQRDELSYHKKKEcdWKLLNQLtkraytNRLFITHLS 246
Cdd:COG1289  211 YL-----RALLSQGDPADDlalRAARRRLAAALAALEALLQRALSEPPRGRRRE--LRALLAL------NHRLLSLLS 275
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
14-151 2.26e-12

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 67.69  E-value: 2.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456   14 TIKTGIAIFLtAVFC-MALDL-TPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGdQSPFTYALSAT 91
Cdd:pfam04632   4 ALKTFLAAML-ALYIaLRLELpQPYWAMTTVFIVSQPLSGAVLSKSFYRLLGTLVGAAAAVLLVALFV-QAPLLFLLALA 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446922456   92 FTILFCTKLKLQVGTN---VAVLT--SLAMI--PGIHDAY-IFNF-LSRTLTAIIGLVTSGLINFMVFP 151
Cdd:pfam04632  82 LWIGLCLALSLLDRNFrsyAFVLAgyTAAIIglPAVADPEaIFDIaVARVSEISLGILCAALVSALVFP 150
ALMT pfam11744
Aluminium activated malate transporter;
36-214 8.60e-07

Aluminium activated malate transporter;


Pssm-ID: 432042 [Multi-domain]  Cd Length: 408  Bit Score: 50.05  E-value: 8.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456   36 IYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYL---FGDQ--------SPFTYALSATFTILFCT-KLKLQ 103
Cdd:pfam11744  42 VWAILTVVVVFEFSVGATLSKGLNRGLATLIAGGLAFGVHHLassSGKIgepivigvSVFIIGFAATFSRFHPAiKARYD 121
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446922456  104 VGTNVAVLT-SLAMIPGIHDAYIFNF-LSRTLTAIIGLVTSGLINFMVFP----PKYYGQVEEKLSKTDALMYKLFYNRC 177
Cdd:pfam11744 122 YGFRVFLLTfCLVTVSGYRTDEFIETaHQRFYTIAIGAGICLIVSIFIFPiwagEDLHKLVAKNFEKLANSLEGCVNEYL 201
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 446922456  178 QELILSRLQSDKSEKA-------YKNIFNLNNQVETLISYQRDE 214
Cdd:pfam11744 202 EEVEYERSILEYEDDSddslyngYKSVLNSKSQEESLANFAKWE 245
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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